408:. The US FDA announced the approval of pralatrexate in 2009 for the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL). Research on drugs of this class began at SRI International in the 1950s. Pralatrexate was first prepared there by Dr. Joseph DeGraw and Dr. William Colwell. Dr. Robert Piper at Southern Research synthesized the key starting material (a bromomethyl compound) which was used to prepare the intermediates needed to make multigram quantities of high purity final compound. Multiple issued patents on this compound are jointly owned by Southern Research, SRI International and Memorial Sloan Kettering and licensed to Allos Therapeutics.
461:, clean air, and clean water. Southern Research develops and tests air and water emissions control technologies for leading utilities, industrial manufacturers, municipal water utilities, and related trade organizations. The division has also historically partnered with private sector firms and government agencies to develop new technologies that transform
105:
Before joining
Southern Research, Carpenter served as director of the Innovation and Economic Opportunity Department for the City of Birmingham, where he led the city's efforts in workforce development, COVID recovery and business expansion. Previously, he worked as the director of External Affairs
73:
15,000 per year for five years, $ 75,000 total, and this was enough for the organization to finance laboratory space and hire researchers and staff. The following year, 1944, the decision was made to change the institute's name from
Alabama Research Institute, to Southern Research Institute.
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MLP was founded by the NIH to fund research aimed at identifying new chemical probes against biological targets that might be amenable for drug therapy. Southern
Research was one of eight extramural institutes selected for this initiative along with the
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Around this same time, Southern
Research Institute hired its first director, Wilbur Lazier. Though he only stayed in this role for four years, Lazier is credited with recruiting many figures that shaped the history of the organization, including
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of
Materials; Electrical, EO/IR, and Mechanical Systems; Hypersonic Structures; Space Structures Characterization; Mechanical Testing of Materials Structures and Components; and Thermal Testing of Materials.
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Bonate, Peter L.; Arthaud, Larry; Cantrell, William R.; Stephenson, Katherine; Secrist, John A.; Weitman, Steve (2006). "Discovery and development of clofarabine: a nucleoside analogue for treating cancer".
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235:(CRO), Southern Research provides commercial and government clients with nonclinical and clinical trial support services. They offer studies including both in vitro and in vivo testing of small
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Michael D. Johns is the vice president of
Engineering at Southern Research. He also serves on NASA Space Technology Mission Directorate's Technology, Innovation and Engineering Committee.
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298:(SOM). The UAB Center for Clinical and Translational Science (CCTS), and the UAB Comprehensive Cancer Center (CCC) are also crucial contributors to the ADDA.
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at the
University of Alabama at Birmingham, as an assistant professor of economics at UAB and as a non-resident senior fellow at The Brookings Institution.
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In 2014, Southern
Research and the University of Alabama at Birmingham formed the Alliance for Innovative Medical Technology (AIMTech) to develop new
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is another anticancer drug whose discovery was a result of contributions from medicinal chemists at
Southern Research along with chemists from
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Although Martin was named chairman of the newly chartered organization in
December, 1941, activities were put on hold in the aftermath of the
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research organization that conducts basic and applied research for commercial and non-commercial organizations across four divisions:
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1273:"Southern Research awarded $ 500,000 U.S. Department of Commerce grant to expand medical device innovation and commercialization"
1244:"Southern Research awarded $ 500,000 U.S. Department of Commerce grant to expand medical device innovation and commercialization"
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at the end of 2004 for the treatment of paediatric patients 1–21 years old with relapsed or refractory acute lymphoblastic
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Southern Research celebrated its 75th anniversary in October 2016. In celebration of this milestone the director of
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Southern Research's Drug Development division is the largest of the organization's four divisions. Set up like a
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305:(NAI) in recognition of his wide-ranging contributions to pharmaceutical research and drug discovery efforts.
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1047:"The NIH Molecular Libraries Program: Identifying Chemical Probes for New Medicines | BioScreening.net"
66:, Martin reengaged the Alabama's industrial leaders and received over $ 100,000 in philanthropic donations.
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Mark J. Suto is vice president of Drug Discovery at Southern Research. He has been named a Fellow of the
759:"Cyclenium Pharma and Southern Research Institute Announce Drug Discovery and Development Collaboration"
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in more than a decade, and the first to receive approval for paediatric use before adult use.
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after at least two prior regimens. It is the first such drug to be approved for paediatric
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255:. Current service areas include: Bioanalytical Analysis; Anticancer Efficacy Services;
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838:"Southern Research Institute names Dr. Mark Suto as VP of Drug Discovery Division"
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research program was started in 1946 with a $ 25,000 philanthropic donation from
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to hit the market by 2020. By comparison, it can take 10 years to create an
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51:, on October 11, 1941, by Thomas Martin as the Alabama Research Institute.
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809:"Southern Research: Making Strides in Life-Changing Science for 75 Years"
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is a nucleoside discovered at Southern Research that eventually received
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Southern Research's Drug Discovery division conducts research focused on
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62:. Two years later, in December 1943, with a promise of support from the
716:"Southern Research at 75: Discovering cancer drugs and extending lives"
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The organization's scientists are credited with the discovery of seven
93:, produced a video congratulating the organization on its anniversary.
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The creation of medical devices are across all five specializations:
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630:"Tom Martin, Alabama Power and the founding of Southern Research"
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grant to expand medical device innovation and commercialization.
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Southern Research's Energy & Environment division focuses on
1161:"How Southern Research helped the program log 542 million miles"
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Current areas include: Non destructive evaluation of materials;
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researchers who worked at the institute include Y Fulmer Shealy
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1103:"Southern Research New NASA Contract of Nearly $ 10 million"
997:"FDA Approval for Pralatrexate - National Cancer Institute"
247:, and other test articles in therapeutic areas including
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784:"Southern Research contracted for Zika drug discovery"
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University of Alabama at Birmingham School of Medicine
662:"Alabama Power and the founding of Southern Research"
547:. The goal is for the first group of AIMTech-created
368:, John Montgomery, Frank Schabel and Lee Bennett Jr.
1022:"Molecular Libraries Program » Pilot Program"
1335:Medical and health organizations based in Alabama
1325:Medical research institutes in the United States
1132:"Michael D. Johns Named to Top Engineering Post"
1330:Cancer organizations based in the United States
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558:In 2016, AIMTech was awarded a $ 500,000 U.S.
491:National Aeronautics and Space Administration
103:named president and CEO of Southern Research.
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332:(FDA) approved anti-cancer drugs, including
69:Alabama Power Company pledged an additional
1186:"U.S. Economic Development Administration"
423:Sanford-Burnham Medical Research Institute
1219:U.S. Economic Development Administration
1190:U.S. Economic Development Administration
921:"Ben May's Gift Launches Cancer Program"
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58:and the beginning of US involvement in
1340:BSL3 laboratories in the United States
406:Memorial Sloan-Kettering Cancer Center
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1071:Harney, Erin (23 September 2016).
112:Southern Research Past Presidents
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101:In June 2021, Josh Carpenter was
47:Southern Research was founded in
1101:Beyerle, Dana (11 August 2016).
35:, Energy & Environment, and
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1254:from the original on 2016-12-21
1225:from the original on 2018-09-07
1196:from the original on 2018-09-07
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1142:from the original on 2016-12-20
1113:from the original on 2019-07-08
1083:from the original on 2019-02-13
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902:from the original on 2017-08-19
873:from the original on 2017-05-29
848:from the original on 2018-09-08
819:from the original on 2017-02-01
790:from the original on 2017-06-10
786:. Birmingham Business Journal.
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697:from the original on 2019-05-22
672:from the original on 2019-02-16
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611:from the original on 2016-10-13
344:developed by Y Fulmer Shealy,
233:contract research organization
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955:Nature Reviews Drug Discovery
303:National Academy of Inventors
87:National Institutes of Health
360:(approved in 2009). Notable
330:Food and Drug Administration
1107:Business Council of Alabama
412:Molecular libraries program
210:William M. Murray Jr., PhD
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844:. AL.com. 12 August 2011.
431:Scripps Research Institute
691:"Encyclopedia of Alabama"
601:"About Southern Research"
497:and other organizations.
140:John A. Secrist III, PhD
111:
439:University of New Mexico
427:Johns Hopkins University
668:. Alabama News Center.
666:Alabama%20News%20Center
524:to improve healthcare.
200:Howard E. Skipper, PhD
180:John W. Rouse Jr., PhD
560:Department of Commerce
449:Energy and environment
220:Wilbur A. Lazier, PhD
160:J. David Prejean, PhD
130:Arthur J. Tipton, PhD
56:attack on Pearl Harbor
1163:. Southern Research.
1073:"Alabama News Center"
718:. Southern Research.
580:U.S. patent 5,661,136
573:U.S. patent 5,384,310
489:have worked with the
435:Vanderbilt University
64:Alabama Power Company
1138:. The Free Library.
443:University of Kansas
1077:Alabama News Center
925:Alabama News Center
867:"Southern Research"
813:Protective Newsroom
634:Alabama News Center
190:Sabert Oglesby Jr.
150:Robert C. Lonergan
49:Birmingham, Alabama
927:. 3 October 2016.
636:. 7 October 2016.
485:Southern Research
475:water purification
467:chemical synthesis
313:Southern Research
285:infectious disease
261:Infectious Disease
249:infectious disease
1277:Southern Research
745:Southern Research
605:Southern Research
402:SRI International
366:Howard E. Skipper
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170:Gilbert E. Dwyer
80:Howard E. Skipper
17:Southern Research
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493:(NASA), the
484:
465:generation,
459:clean energy
452:
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398:Pralatrexate
396:
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358:pralatrexate
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533:Orthopedics
481:Engineering
380:Clofarabine
372:Clofarabine
354:clofarabine
346:fludarabine
342:dacarbazine
239:compounds,
216:1944 - 1948
206:1948 - 1974
196:1974 - 1980
186:1981 - 1987
176:1987 - 1997
166:1997 - 1999
156:1999 - 2000
146:2001 - 2006
136:2006 - 2013
126:2013 – 2019
37:Engineering
1314:Categories
1287:2020-03-04
1258:2020-03-04
1229:2020-03-04
1200:2020-03-04
1171:2020-03-04
1146:2020-03-04
1117:2020-03-04
1087:2020-03-04
1057:2011-03-06
1032:2011-03-06
1007:2009-12-05
935:2020-03-04
906:2020-03-04
877:2020-03-04
852:2020-03-04
823:2020-03-04
794:2020-03-04
769:2020-03-04
726:2020-03-04
701:2020-03-04
676:2020-03-04
644:2020-03-04
615:2016-11-15
587:References
529:Cardiology
455:technology
378:approval.
350:amifostine
334:carmustine
323:Ben E. May
319:Mobile, AL
269:Consulting
257:Immunology
251:, CNS and
97:Leadership
1250:. Yahoo.
1215:"EDA.gov"
502:Chemistry
487:engineers
392:leukaemia
388:leukaemia
338:lomustine
265:Pathology
245:biologics
25:501(c)(3)
1281:Archived
1252:Archived
1223:Archived
1194:Archived
1165:Archived
1140:Archived
1111:Archived
1081:Archived
1051:Archived
1001:Archived
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817:Archived
788:Archived
763:Archived
720:Archived
695:Archived
670:Archived
638:Archived
609:Archived
441:and the
281:oncology
241:vaccines
237:molecule
566:Patents
516:AIMTech
506:Physics
89:(NIH),
43:History
981:
973:
842:AL.com
545:Trauma
469:, and
463:energy
362:cancer
315:cancer
287:, and
267:; and
253:cancer
1248:Yahoo
979:S2CID
896:Yahoo
120:Name
117:Year
19:is a
971:PMID
543:and
504:and
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