314:
291:
6207:
188:
213:
565:
320:
219:
6146:
1375:
has been discovered. TNFR2 plays a significant role in tumor cell growth as it has been found that the loss of TNFR2 expression is linked with increased death of associated tumor cells and a significant standstill of further growth. There is therapeutic potential in the targeting of TNFR2 for cancer
63:
2193:"Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1"
5529:
1944:
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, et al. (February 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway".
1909:
Komata T, Tsuchiya N, Matsushita M, Hagiwara K, Tokunaga K (June 1999). "Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus".
5104:
3338:
2269:"TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation"
2477:
327:
226:
1384:
A small scale study of 289 Japanese patients suggested a minor increased predisposition from an amino acid substitution of the 196 allele at exon 6. Genomic testing of 81
5522:
120:, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR, tumor necrosis factor receptor superfamily member 1B, TNF receptor superfamily member 1B
2383:"A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: a case-control study and a meta-analysis"
2360:
Holtmann MH, Schuchmann M, Zeller G, Galle PR, Neurath MF (2003). "The emerging distinct role of TNF-receptor 2 (p80) signaling in chronic inflammatory disorders".
1805:"Plasma Levels of Soluble Tumor Necrosis Factor Receptor 2 (sTNFR2) Are Associated with Hippocampal Volume and Cognitive Performance in Patients with Schizophrenia"
5227:
3328:
2232:
Carpentier I, Coornaert B, Beyaert R (October 2008). "Smurf2 is a TRAF2 binding protein that triggers TNF-R2 ubiquitination and TNF-R2-induced JNK activation".
5515:
4514:
1268:. TNFR1 and TNFR2 possess different functions when bound to TNFα due to differences in their intracellular structures, such as TNFR2 lacking a death domain (
3308:
978:
959:
4904:
4170:
2494:
2470:
149:
5475:
5193:
5189:
5172:
3901:
6277:
6248:
5306:
5281:
5145:
3889:
3667:
2430:
2308:
1987:
1852:
1564:
1341:
6191:
5963:
5310:
5285:
5136:
3953:
3948:
3894:
3674:
2455:
1499:
1481:
6267:
5463:
5162:
5097:
3407:
3333:
2463:
5813:
5157:
4436:
4431:
4426:
4421:
3348:
2052:"Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins"
313:
1185:
1178:
4401:
290:
5601:
5036:
4733:
4507:
3637:
1733:
1261:
1352:
Targeting of TNRF2 in tumor cells is associated with increased tumor cell death and decreased progression of tumor cell growth.
1320:
studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
5838:
5384:
4682:
4205:
3699:
3385:
1468:
1447:
5592:
5379:
5327:
4718:
3844:
3380:
1281:
1464:
1304:
activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced
212:
187:
60:
4631:
4593:
4588:
4341:
3813:
3808:
3753:
3487:
2936:
1443:
6272:
4636:
4035:
3758:
326:
225:
129:
2331:(2003). "Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments".
1388:
patients and 207 healthy patients in a
Japanese study showed 37% of SLE patients had a polymorphism on position 196 of
6282:
5663:
5627:
5348:
5344:
4500:
3353:
2003:"Association of a RING finger protein with the cytoplasmic domain of the human type-2 tumour necrosis factor receptor"
1405:
1257:
5049:
1866:
Medler J, Wajant H (April 2019). "Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target".
319:
218:
6241:
5364:
4980:
4536:
4065:
2490:
6184:
5889:
5552:
5340:
5264:
4963:
4749:
2931:
5884:
5538:
5494:
5458:
4989:
4115:
3010:
2449:
1624:"Tumor necrosis factor receptor 2: its contribution to acute cellular rejection and clear cell renal carcinoma"
1023:
137:
5413:
5391:
5315:
5302:
5289:
5277:
5245:
5232:
5222:
5198:
5185:
5141:
5132:
5059:
5032:
5023:
4618:
4079:
1004:
6098:
5450:
5374:
5127:
5093:
5084:
5054:
5045:
5028:
4626:
4546:
3422:
3417:
3412:
3402:
2709:
2637:
2328:
6234:
5152:
2766:
2684:
2424:
2302:
1981:
1846:
1558:
1392:
6 compared to 18.8% of healthy patients. The TNFR2 196R allele polymorphism suggests that even one 196R
1265:
5917:
1264:, the extracellular region of TNFR2 consists of four cysteine-rich domains which allow for binding to
6177:
5272:
5180:
5122:
5079:
5006:
4003:
3716:
2145:
201:
116:
6058:
5993:
5909:
5489:
5484:
5322:
4030:
3849:
2267:
Pype S, Declercq W, Ibrahimi A, Michiels C, Van
Rietschoten JG, Dewulf N, et al. (June 2000).
1580:"Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization"
1301:
6128:
5796:
5692:
5658:
5648:
5622:
5612:
5582:
5544:
5479:
5250:
4998:
4531:
3437:
3171:
1969:
1891:
1546:
161:
6108:
5978:
5973:
5757:
5717:
2381:
Horiuchi T, Kiyohara C, Tsukamoto H, Sawabe T, Furugo I, Yoshizawa S, et al. (March 2007).
2093:"Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b"
1161:
1140:
1114:
1093:
5737:
1340:
Patients with schizophrenia have increased levels of soluble tumor necrosis factor receptor 2 (
564:
5742:
5653:
5617:
5567:
4523:
2412:
2369:
2348:
2290:
2249:
2214:
2173:
2114:
2073:
2032:
1961:
1926:
1883:
1834:
1785:
1715:
1655:
1601:
1538:
1364:
157:
109:
53:
6218:
6161:
2134:"I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction"
6206:
5571:
5438:
5241:
5114:
4955:
4947:
4848:
4840:
4832:
4824:
4210:
3943:
3864:
3427:
2620:
2546:
2402:
2394:
2340:
2280:
2241:
2204:
2163:
2153:
2104:
2063:
2022:
2014:
1953:
1918:
1875:
1824:
1816:
1775:
1767:
1705:
1695:
1645:
1635:
1591:
1530:
406:
337:
281:
236:
5933:
5913:
5879:
4864:
4270:
2806:
2801:
2724:
2445:
1360:
1334:
381:
804:
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
2149:
5948:
5828:
4765:
4055:
3477:
2988:
2791:
2407:
2382:
2027:
2002:
1829:
1804:
1803:
Kudo N, Yamamori H, Ishima T, Nemoto K, Yasuda Y, Fujimoto M, et al. (July 2018).
1780:
1755:
1710:
1683:
1650:
1623:
1372:
1309:
5507:
2344:
1922:
893:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
838:
833:
828:
823:
818:
813:
808:
803:
798:
793:
788:
783:
778:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
723:
718:
713:
697:
692:
687:
682:
677:
672:
667:
662:
657:
652:
647:
642:
637:
621:
616:
611:
606:
6261:
5217:
5011:
4025:
3482:
2573:
2168:
2133:
1534:
1368:
1356:
1317:
593:
1973:
1895:
1550:
141:
6214:
6157:
6093:
6018:
5874:
5833:
5818:
5747:
5712:
5405:
4773:
4381:
3689:
3679:
3210:
3176:
1754:
Chadwick W, Magnus T, Martin B, Keselman A, Mattson MP, Maudsley S (October 2008).
1292:
form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins,
1269:
399:
178:
1879:
1517:
Schall TJ, Lewis M, Koller KJ, Lee A, Rice GC, Wong GH, et al. (April 1990).
165:
6073:
6068:
6063:
6038:
6033:
6028:
6003:
5998:
5938:
5851:
5787:
5707:
5563:
4598:
4573:
4391:
4040:
3818:
3793:
3492:
3114:
3040:
2514:
2109:
2092:
1519:"Molecular cloning and expression of a receptor for human tumor necrosis factor"
1504:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1486:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2245:
2138:
Proceedings of the
National Academy of Sciences of the United States of America
1771:
482:
6118:
6088:
6083:
6048:
6023:
6013:
5923:
5767:
5732:
5722:
5702:
5687:
5682:
4321:
4045:
3726:
3467:
3343:
2976:
2971:
2966:
2821:
2605:
298:
195:
145:
2209:
2192:
2191:
Marsters SA, Ayres TM, Skubatch M, Gray CL, Rothe M, Ashkenazi A (May 1997).
2132:
Rothe M, Xiong J, Shu HB, Williamson K, Goddard A, Goeddel DV (August 1996).
2068:
2051:
1734:"Entrez Gene: TNFRSF1B tumor necrosis factor receptor superfamily, member 1B"
1700:
1596:
1579:
6053:
6008:
5988:
5781:
5772:
5697:
4888:
4880:
4872:
4160:
4155:
4150:
4140:
4135:
4130:
4125:
2398:
2158:
1518:
1305:
923:
542:
420:
365:
352:
264:
251:
153:
2416:
2373:
2352:
2294:
2285:
2268:
2253:
2118:
1965:
1930:
1887:
1838:
1789:
1719:
1659:
2218:
2177:
2077:
2036:
1820:
1640:
1605:
1542:
1333:
At least partly because TNFR2 has no intracellular death domain, TNFR2 is
1225:
1220:
6078:
6043:
5807:
5803:
5791:
5777:
4928:
4920:
4912:
4896:
4466:
4366:
4180:
4165:
3368:
3363:
3271:
2961:
1289:
1285:
1209:
1068:
1049:
5958:
5928:
5297:
5293:
5040:
4416:
4411:
4406:
4306:
4120:
4110:
3937:
3916:
3911:
3879:
3684:
3604:
3599:
3594:
3589:
3584:
3502:
3195:
3035:
3030:
3025:
3020:
3015:
2486:
1035:
990:
2018:
86:
82:
5433:
5428:
5423:
5418:
5395:
5335:
5331:
5071:
4704:
4492:
4356:
4316:
4301:
4285:
4280:
4260:
4255:
4190:
3998:
3968:
3932:
3923:
3736:
3704:
3568:
3563:
3533:
3512:
3472:
3432:
3298:
3276:
3235:
3159:
3154:
3149:
3144:
3139:
3134:
3003:
2998:
2993:
2941:
2926:
2796:
2786:
2749:
2744:
2662:
2657:
1393:
1193:
945:
17:
6145:
1957:
5953:
5943:
5904:
5899:
5846:
5468:
5088:
5019:
5015:
4805:
4757:
4699:
4663:
4658:
4653:
4648:
4643:
4608:
4568:
4558:
4481:
4456:
4376:
4371:
4361:
4351:
4336:
4331:
4326:
4311:
4265:
4250:
4215:
4200:
4195:
4185:
4105:
4100:
4095:
4074:
4070:
4060:
3973:
3874:
3869:
3828:
3778:
3773:
3768:
3763:
3748:
3741:
3721:
3709:
3652:
3647:
3642:
3632:
3627:
3620:
3558:
3548:
3543:
3538:
3528:
3507:
3497:
3462:
3457:
3452:
3447:
3442:
3397:
3392:
3358:
3323:
3318:
3313:
3303:
3291:
3286:
3266:
3261:
3256:
3251:
3205:
3097:
3092:
2911:
2895:
2888:
2883:
2878:
2873:
2868:
2863:
2838:
2816:
2811:
2704:
2630:
2625:
2615:
1418:
1412:
1313:
1297:
1293:
834:
positive regulation of apoptotic process involved in morphogenesis
908:
904:
824:
negative regulation of extracellular matrix constituent secretion
6153:
5894:
4856:
4797:
4789:
4781:
4692:
4603:
4583:
4578:
4563:
4554:
4476:
4471:
4461:
4451:
4446:
4441:
4396:
4386:
4346:
4275:
4245:
4240:
4235:
4230:
4225:
4220:
4175:
4145:
4050:
4018:
4013:
3993:
3983:
3978:
3963:
3958:
3859:
3854:
3823:
3803:
3798:
3788:
3783:
3662:
3615:
3575:
3230:
3225:
3220:
3215:
3200:
3191:
3186:
3181:
3166:
3124:
3119:
3109:
3104:
3087:
3082:
3077:
3072:
3067:
3062:
3057:
3052:
3047:
2983:
2956:
2951:
2946:
2921:
2916:
2853:
2848:
2843:
2833:
2828:
2781:
2776:
2771:
2761:
2756:
2739:
2734:
2729:
2719:
2714:
2699:
2694:
2689:
2679:
2674:
2669:
2652:
2647:
2642:
2593:
2561:
2556:
2551:
2534:
2529:
2524:
2519:
1389:
133:
5511:
4496:
2459:
1684:"TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors"
764:
intrinsic apoptotic signaling pathway in response to DNA damage
573:
5823:
3988:
2600:
2588:
2583:
2578:
2568:
2541:
2509:
1385:
729:
positive regulation of membrane protein ectodomain proteolysis
1371:. A link between the expression of TNRF2 in tumor cells and
389:
6222:
6165:
869:
positive regulation of oligodendrocyte differentiation
1756:"Targeting TNF-alpha receptors for neurotherapeutics"
1312:
and degradation of TNF-receptor-associated factor 2 (
554:
1809:
1280:
The protein encoded by this gene is a member of the
1246:
tumor necrosis factor receptor superfamily member 1B
5864:
5672:
5636:
5600:
5591:
5551:
5449:
5404:
5363:
5263:
5209:
5171:
5113:
5070:
4997:
4988:
4979:
4940:
4817:
4726:
4717:
4672:
4617:
4545:
4530:
4294:
4088:
3837:
3521:
3244:
2904:
2502:
2234:
1154:
1133:
1107:
1086:
1460:
1458:
1456:
1439:
1437:
1435:
698:tumor necrosis factor receptor superfamily complex
2362:Archivum Immunologiae et Therapiae Experimentalis
879:negative regulation of neuroinflammatory response
829:negative regulation of cardiac muscle hypertrophy
617:tumor necrosis factor-activated receptor activity
336:
235:
794:tumor necrosis factor-mediated signaling pathway
2050:Takeuchi M, Rothe M, Goeddel DV (August 1996).
1465:GRCm38: Ensembl release 89: ENSMUSG00000028599
1256:, is one of two membrane receptors that binds
6242:
6185:
5539:
5523:
4508:
2471:
8:
1677:
1675:
1673:
1671:
1669:
784:negative regulation of inflammatory response
1617:
1615:
1444:GRCh38: Ensembl release 89: ENSG00000028137
754:regulation of cell population proliferation
724:cellular response to growth factor stimulus
6249:
6235:
6192:
6178:
5597:
5530:
5516:
5508:
4994:
4985:
4723:
4542:
4515:
4501:
4493:
2478:
2464:
2456:
1355:Increased expression of TNFR2 is found in
1316:), which mediates anti-apoptotic signals.
919:
859:cellular response to tumor necrosis factor
589:
377:
276:
173:
71:
5944:RANKL (TRANCE, OPGL, ODF, CD254, TNFSF11)
2495:list of human clusters of differentiation
2448:at the U.S. National Library of Medicine
2406:
2284:
2208:
2167:
2157:
2108:
2067:
2026:
1828:
1779:
1709:
1699:
1649:
1639:
1595:
1578:Santee SM, Owen-Schaub LB (August 1996).
27:Membrane receptor protein found in humans
1262:tumor necrosis factor receptor 1 (TNFR1)
854:regulation of neuroinflammatory response
839:regulation of T cell cytokine production
1431:
779:cellular response to lipopolysaccharide
744:cell surface receptor signaling pathway
2422:
2300:
1979:
1844:
1556:
894:regulation of RNA biosynthetic process
31:
2091:Hostager BS, Bishop GA (April 2002).
1868:Expert Opinion on Therapeutic Targets
1376:treatments through TNFR2 inhibition.
714:extrinsic apoptotic signaling pathway
653:integral component of plasma membrane
341:
302:
297:
240:
199:
194:
7:
6203:
6201:
6142:
6140:
2333:Cytokine & Growth Factor Reviews
2273:The Journal of Biological Chemistry
2197:The Journal of Biological Chemistry
2056:The Journal of Biological Chemistry
1584:The Journal of Biological Chemistry
1396:results in increased risk for SLE.
889:negative regulation of neuron death
809:cytokine-mediated signaling pathway
6221:. You can help Knowledge (XXG) by
6164:. You can help Knowledge (XXG) by
2429:: CS1 maint: overridden setting (
2307:: CS1 maint: overridden setting (
2001:Song HY, Donner DB (August 1995).
1986:: CS1 maint: overridden setting (
1851:: CS1 maint: overridden setting (
1622:Wang J, Al-Lamki RS (2013-11-17).
1563:: CS1 maint: overridden setting (
1151:
1130:
1104:
1083:
1059:
1040:
1014:
995:
969:
950:
864:positive regulation of myelination
849:regulation of T cell proliferation
739:multicellular organism development
559:
477:
415:
394:
25:
1923:10.1034/j.1399-0039.1999.530602.x
1380:Systemic Lupus Erythematous (SLE)
1284:superfamily, which also contains
874:negative regulation of cell death
6205:
6144:
5872:TNF superfamily protein ligands:
2387:Annals of the Rheumatic Diseases
1238:Tumor necrosis factor receptor 2
612:ubiquitin protein ligase binding
563:
325:
318:
312:
289:
224:
217:
211:
186:
678:perinuclear region of cytoplasm
1282:tumor necrosis factor receptor
1260:(TNFα). Like its counterpart,
749:response to lipopolysaccharide
638:integral component of membrane
574:More reference expression data
543:More reference expression data
1:
6278:Human chromosome 1 gene stubs
5934:LIGHT (HEVML, CD258, TNFSF14)
2345:10.1016/S1359-6101(02)00019-9
1880:10.1080/14728222.2019.1586886
1682:Sheng Y, Li F, Qin Z (2018).
1628:BioMed Research International
622:tumor necrosis factor binding
310:
209:
1535:10.1016/0092-8674(90)90816-W
6268:Genes on human chromosome 1
2491:clusters of differentiation
2110:10.4049/jimmunol.168.7.3318
1404:TNFRSF1B has been shown to
1258:tumor necrosis factor-alpha
884:glial cell-neuron signaling
819:pulmonary valve development
769:apoptotic signaling pathway
463:subcutaneous adipose tissue
6299:
6200:
6139:
2246:10.1016/j.bbrc.2008.07.103
1772:10.1016/j.tins.2008.07.005
1500:"Mouse PubMed Reference:"
1482:"Human PubMed Reference:"
1224:
1219:
1215:
1208:
1192:
1186:Chr 4: 144.94 – 144.97 Mb
1173:
1158:
1137:
1126:
1111:
1090:
1079:
1066:
1062:
1047:
1043:
1034:
1021:
1017:
1002:
998:
989:
976:
972:
957:
953:
944:
929:
922:
918:
902:
844:regulation of myelination
693:specific granule membrane
592:
588:
571:
562:
553:
540:
489:
480:
427:
418:
388:
380:
376:
359:
346:
309:
288:
279:
275:
258:
245:
208:
185:
176:
172:
127:
124:
114:
107:
102:
79:
74:
57:
52:
47:
43:
39:
34:
2450:Medical Subject Headings
2210:10.1074/jbc.272.22.14029
2069:10.1074/jbc.271.33.19935
1701:10.3389/fimmu.2018.01170
1597:10.1074/jbc.271.35.21151
814:aortic valve development
799:neutrophil degranulation
451:tendon of biceps brachii
5875:4-1BBL (CD137L, TNFSF9)
2399:10.1136/ard.2006.058917
2159:10.1073/pnas.93.16.8241
2007:The Biochemical Journal
1760:Trends in Neurosciences
1688:Frontiers in Immunology
1179:Chr 1: 12.17 – 12.21 Mb
529:internal carotid artery
6099:Vorsetuzumab mafodotin
5954:TRAIL (CD253, TNFSF10)
5885:BAFF (CD257, TNFSF13B)
5880:APRIL (CD256, TNFSF13)
5451:Enzyme-linked receptor
2286:10.1074/jbc.M000531200
517:mesenteric lymph nodes
5971:Recombinant proteins:
5939:OX40L (CD252, TNFSF4)
5905:CD154 (CD40L, TNFSF5)
5900:CD153 (CD30L, TNFSF8)
5273:Interleukin receptors
5181:Interleukin receptors
5123:Interleukin receptors
5080:Interleukin receptors
5007:Interleukin receptors
2097:Journal of Immunology
1324:Clinical significance
774:inflammatory response
497:stroma of bone marrow
5964:VEGI (TL1A, TNFSF15)
5924:FasL (CD95L, TNFSF6)
5895:CD70 (CD27L, TNFSF7)
5542:receptor superfamily
5323:Interferon receptors
663:extracellular region
343:4 E1|4 78.17 cM
304:Chromosome 4 (mouse)
202:Chromosome 1 (human)
166:TNFRSF1B - orthologs
75:List of PDB id codes
48:Available structures
6273:TNF receptor family
5994:Brentuximab vedotin
2279:(24): 18586–18593.
2203:(22): 14029–14032.
2150:1996PNAS...93.8241R
2062:(33): 19935–19942.
1946:Nature Cell Biology
1821:10.1093/ijnp/pyy013
1641:10.1155/2013/821310
1590:(35): 21151–21159.
1302:E3 ubiquitin ligase
1288:. This protein and
719:RNA destabilization
6283:Biochemistry stubs
6152:This article on a
5797:Echinacea purpurea
5755:Enzyme inhibitors:
5693:Certolizumab pegol
4532:Chemokine receptor
4524:Cytokine receptors
1024:ENSMUSG00000028599
707:Biological process
673:neuronal cell body
631:Cellular component
600:Molecular function
6230:
6229:
6173:
6172:
6137:
6136:
6116:Other inhibitors:
5860:
5859:
5841:
5765:Other inhibitors:
5505:
5504:
5359:
5358:
5259:
5258:
4975:
4974:
4713:
4712:
4490:
4489:
2144:(16): 8241–8246.
2019:10.1042/bj3090825
1373:late-stage cancer
1244:), also known as
1235:
1234:
1231:
1230:
1204:
1203:
1169:
1168:
1148:
1147:
1122:
1121:
1101:
1100:
1075:
1074:
1056:
1055:
1030:
1029:
1011:
1010:
985:
984:
966:
965:
914:
913:
789:apoptotic process
584:
583:
580:
579:
549:
548:
536:
535:
474:
473:
467:periodontal fiber
372:
371:
271:
270:
98:
97:
94:
93:
58:Ortholog search:
16:(Redirected from
6290:
6251:
6244:
6237:
6209:
6202:
6194:
6187:
6180:
6148:
6141:
6106:Decoy receptors:
5839:
5730:Decoy receptors:
5598:
5580:Decoy receptors:
5541:
5532:
5525:
5518:
5509:
5242:hormone receptor
4995:
4986:
4724:
4543:
4517:
4510:
4503:
4494:
2480:
2473:
2466:
2457:
2434:
2428:
2420:
2410:
2377:
2356:
2339:(4–5): 315–321.
2313:
2312:
2306:
2298:
2288:
2264:
2258:
2257:
2229:
2223:
2222:
2212:
2188:
2182:
2181:
2171:
2161:
2129:
2123:
2122:
2112:
2103:(7): 3318–3322.
2088:
2082:
2081:
2071:
2047:
2041:
2040:
2030:
1998:
1992:
1991:
1985:
1977:
1941:
1935:
1934:
1906:
1900:
1899:
1863:
1857:
1856:
1850:
1842:
1832:
1800:
1794:
1793:
1783:
1751:
1745:
1744:
1742:
1740:
1730:
1724:
1723:
1713:
1703:
1679:
1664:
1663:
1653:
1643:
1619:
1610:
1609:
1599:
1575:
1569:
1568:
1562:
1554:
1514:
1508:
1507:
1496:
1490:
1489:
1478:
1472:
1462:
1451:
1441:
1300:, which possess
1217:
1216:
1188:
1181:
1164:
1152:
1143:
1131:
1127:RefSeq (protein)
1117:
1105:
1096:
1084:
1060:
1041:
1015:
996:
970:
951:
920:
590:
576:
567:
560:
545:
485:
483:Top expressed in
478:
423:
421:Top expressed in
416:
395:
378:
368:
355:
344:
329:
322:
316:
305:
293:
277:
267:
254:
243:
228:
221:
215:
204:
190:
174:
168:
119:
112:
89:
72:
66:
45:
44:
32:
21:
6298:
6297:
6293:
6292:
6291:
6289:
6288:
6287:
6258:
6257:
6256:
6255:
6199:
6198:
6138:
6133:
5959:TWEAK (TNFSF12)
5929:GITRL (TNFSF18)
5856:
5668:
5632:
5587:
5547:
5536:
5506:
5501:
5445:
5400:
5355:
5255:
5205:
5167:
5109:
5066:
4971:
4936:
4865:Osteoprotegerin
4813:
4709:
4668:
4613:
4534:
4526:
4521:
4491:
4486:
4290:
4084:
3833:
3517:
3240:
2900:
2498:
2484:
2442:
2437:
2421:
2380:
2359:
2326:
2322:
2320:Further reading
2317:
2316:
2299:
2266:
2265:
2261:
2231:
2230:
2226:
2190:
2189:
2185:
2131:
2130:
2126:
2090:
2089:
2085:
2049:
2048:
2044:
2000:
1999:
1995:
1978:
1958:10.1038/ncb1086
1943:
1942:
1938:
1911:Tissue Antigens
1908:
1907:
1903:
1865:
1864:
1860:
1843:
1802:
1801:
1797:
1766:(10): 504–511.
1753:
1752:
1748:
1738:
1736:
1732:
1731:
1727:
1681:
1680:
1667:
1621:
1620:
1613:
1577:
1576:
1572:
1555:
1516:
1515:
1511:
1498:
1497:
1493:
1480:
1479:
1475:
1463:
1454:
1442:
1433:
1428:
1402:
1382:
1361:cervical cancer
1350:
1335:neuroprotective
1331:
1326:
1278:
1226:View/Edit Mouse
1221:View/Edit Human
1184:
1177:
1174:Location (UCSC)
1160:
1139:
1113:
1092:
1005:ENSG00000028137
898:
759:immune response
702:
648:plasma membrane
626:
607:protein binding
572:
541:
532:
527:
525:ascending aorta
523:
519:
515:
511:
507:
503:
499:
495:
481:
470:
465:
461:
457:
453:
449:
445:
441:
437:
433:
419:
363:
350:
342:
332:
331:
330:
323:
303:
280:Gene location (
262:
249:
241:
231:
230:
229:
222:
200:
177:Gene location (
128:
115:
108:
81:
59:
28:
23:
22:
15:
12:
11:
5:
6296:
6294:
6286:
6285:
6280:
6275:
6270:
6260:
6259:
6254:
6253:
6246:
6239:
6231:
6228:
6227:
6210:
6197:
6196:
6189:
6182:
6174:
6171:
6170:
6149:
6135:
6134:
6132:
6131:
6122:
6121:
6112:
6111:
6102:
6101:
6096:
6091:
6086:
6081:
6076:
6071:
6066:
6061:
6056:
6051:
6046:
6041:
6036:
6031:
6026:
6021:
6016:
6011:
6006:
6001:
5996:
5991:
5982:
5981:
5976:
5967:
5966:
5961:
5956:
5951:
5946:
5941:
5936:
5931:
5926:
5921:
5907:
5902:
5897:
5892:
5887:
5882:
5877:
5868:
5866:
5862:
5861:
5858:
5857:
5855:
5854:
5849:
5844:
5836:
5831:
5829:Pentoxifylline
5826:
5821:
5816:
5811:
5801:
5785:
5775:
5770:
5761:
5760:
5751:
5750:
5745:
5740:
5735:
5726:
5725:
5720:
5715:
5710:
5705:
5700:
5695:
5690:
5685:
5676:
5674:
5670:
5669:
5667:
5666:
5661:
5656:
5651:
5642:
5640:
5634:
5633:
5631:
5630:
5625:
5620:
5615:
5606:
5604:
5595:
5589:
5588:
5586:
5585:
5576:
5575:
5557:
5555:
5549:
5548:
5537:
5535:
5534:
5527:
5520:
5512:
5503:
5502:
5500:
5499:
5498:
5497:
5492:
5487:
5473:
5472:
5471:
5466:
5455:
5453:
5447:
5446:
5444:
5443:
5442:
5441:
5436:
5431:
5426:
5421:
5410:
5408:
5402:
5401:
5399:
5398:
5389:
5388:
5387:
5382:
5372:
5369:
5367:
5365:Ig superfamily
5361:
5360:
5357:
5356:
5354:
5353:
5352:
5351:
5338:
5320:
5319:
5318:
5313:
5300:
5269:
5267:
5261:
5260:
5257:
5256:
5254:
5253:
5248:
5238:
5237:
5236:
5235:
5233:Thrombopoietin
5230:
5225:
5213:
5211:
5207:
5206:
5204:
5203:
5202:
5201:
5196:
5177:
5175:
5169:
5168:
5166:
5165:
5160:
5155:
5150:
5149:
5148:
5139:
5130:
5119:
5117:
5111:
5110:
5108:
5107:
5102:
5101:
5100:
5091:
5076:
5074:
5068:
5067:
5065:
5064:
5063:
5062:
5057:
5052:
5043:
5026:
5003:
5001:
4992:
4983:
4977:
4976:
4973:
4972:
4970:
4969:
4961:
4953:
4944:
4942:
4938:
4937:
4935:
4934:
4926:
4918:
4910:
4902:
4894:
4886:
4878:
4870:
4862:
4854:
4846:
4838:
4830:
4821:
4819:
4815:
4814:
4812:
4811:
4803:
4795:
4787:
4779:
4771:
4763:
4755:
4747:
4739:
4730:
4728:
4721:
4715:
4714:
4711:
4710:
4708:
4707:
4702:
4697:
4696:
4695:
4687:
4686:
4685:
4676:
4674:
4670:
4669:
4667:
4666:
4661:
4656:
4651:
4646:
4641:
4640:
4639:
4634:
4623:
4621:
4615:
4614:
4612:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4576:
4571:
4566:
4561:
4551:
4549:
4540:
4528:
4527:
4522:
4520:
4519:
4512:
4505:
4497:
4488:
4487:
4485:
4484:
4479:
4474:
4469:
4464:
4459:
4454:
4449:
4444:
4439:
4434:
4429:
4424:
4419:
4414:
4409:
4404:
4399:
4394:
4389:
4384:
4379:
4374:
4369:
4364:
4359:
4354:
4349:
4344:
4339:
4334:
4329:
4324:
4319:
4314:
4309:
4304:
4298:
4296:
4292:
4291:
4289:
4288:
4283:
4278:
4273:
4268:
4263:
4258:
4253:
4248:
4243:
4238:
4233:
4228:
4223:
4218:
4213:
4208:
4203:
4198:
4193:
4188:
4183:
4178:
4173:
4168:
4163:
4158:
4153:
4148:
4143:
4138:
4133:
4128:
4123:
4118:
4113:
4108:
4103:
4098:
4092:
4090:
4086:
4085:
4083:
4082:
4077:
4068:
4063:
4058:
4053:
4048:
4043:
4038:
4033:
4028:
4023:
4022:
4021:
4016:
4006:
4001:
3996:
3991:
3986:
3981:
3976:
3971:
3966:
3961:
3956:
3951:
3946:
3941:
3935:
3926:
3921:
3920:
3919:
3914:
3904:
3899:
3898:
3897:
3892:
3882:
3877:
3872:
3867:
3862:
3857:
3852:
3847:
3841:
3839:
3835:
3834:
3832:
3831:
3826:
3821:
3816:
3811:
3806:
3801:
3796:
3791:
3786:
3781:
3776:
3771:
3766:
3761:
3756:
3751:
3746:
3745:
3744:
3739:
3729:
3724:
3719:
3714:
3713:
3712:
3707:
3702:
3692:
3687:
3682:
3677:
3672:
3671:
3670:
3665:
3655:
3650:
3645:
3640:
3635:
3630:
3625:
3624:
3623:
3618:
3608:
3602:
3597:
3592:
3587:
3578:
3573:
3572:
3571:
3566:
3561:
3551:
3546:
3541:
3536:
3531:
3525:
3523:
3519:
3518:
3516:
3515:
3510:
3505:
3500:
3495:
3490:
3485:
3480:
3475:
3470:
3465:
3460:
3455:
3450:
3445:
3440:
3435:
3430:
3425:
3420:
3415:
3410:
3405:
3400:
3395:
3390:
3389:
3388:
3383:
3373:
3372:
3371:
3366:
3356:
3351:
3346:
3341:
3336:
3331:
3326:
3321:
3316:
3311:
3306:
3301:
3296:
3295:
3294:
3289:
3279:
3274:
3269:
3264:
3259:
3254:
3248:
3246:
3242:
3241:
3239:
3238:
3233:
3228:
3223:
3218:
3213:
3208:
3203:
3198:
3189:
3184:
3179:
3174:
3169:
3164:
3163:
3162:
3157:
3152:
3147:
3142:
3137:
3127:
3122:
3117:
3112:
3107:
3102:
3101:
3100:
3095:
3085:
3080:
3075:
3070:
3065:
3060:
3055:
3050:
3045:
3044:
3043:
3038:
3033:
3028:
3023:
3018:
3008:
3007:
3006:
3001:
2996:
2986:
2981:
2980:
2979:
2974:
2969:
2959:
2954:
2949:
2944:
2939:
2934:
2929:
2924:
2919:
2914:
2908:
2906:
2902:
2901:
2899:
2898:
2893:
2892:
2891:
2886:
2881:
2876:
2871:
2866:
2856:
2851:
2846:
2841:
2836:
2831:
2826:
2825:
2824:
2819:
2814:
2809:
2799:
2794:
2789:
2784:
2779:
2774:
2769:
2764:
2759:
2754:
2753:
2752:
2747:
2737:
2732:
2727:
2722:
2717:
2712:
2707:
2702:
2697:
2692:
2687:
2682:
2677:
2672:
2667:
2666:
2665:
2660:
2650:
2645:
2640:
2635:
2634:
2633:
2628:
2623:
2618:
2608:
2603:
2598:
2597:
2596:
2586:
2581:
2576:
2571:
2566:
2565:
2564:
2559:
2554:
2544:
2539:
2538:
2537:
2532:
2527:
2522:
2517:
2506:
2504:
2500:
2499:
2485:
2483:
2482:
2475:
2468:
2460:
2454:
2453:
2446:CD120b+Antigen
2441:
2440:External links
2438:
2436:
2435:
2393:(3): 320–324.
2378:
2368:(4): 279–288.
2357:
2329:Kontoyiannis D
2323:
2321:
2318:
2315:
2314:
2259:
2240:(4): 752–757.
2224:
2183:
2124:
2083:
2042:
2013:(3): 825–829.
1993:
1936:
1917:(6): 527–533.
1901:
1874:(4): 295–307.
1858:
1815:(7): 631–639.
1795:
1746:
1725:
1665:
1611:
1570:
1529:(2): 361–370.
1509:
1491:
1473:
1452:
1430:
1429:
1427:
1424:
1423:
1422:
1416:
1401:
1398:
1381:
1378:
1349:
1346:
1330:
1327:
1325:
1322:
1310:ubiquitination
1290:TNF-receptor 1
1277:
1274:
1233:
1232:
1229:
1228:
1223:
1213:
1212:
1206:
1205:
1202:
1201:
1199:
1197:
1190:
1189:
1182:
1175:
1171:
1170:
1167:
1166:
1156:
1155:
1149:
1146:
1145:
1135:
1134:
1128:
1124:
1123:
1120:
1119:
1109:
1108:
1102:
1099:
1098:
1088:
1087:
1081:
1077:
1076:
1073:
1072:
1064:
1063:
1057:
1054:
1053:
1045:
1044:
1038:
1032:
1031:
1028:
1027:
1019:
1018:
1012:
1009:
1008:
1000:
999:
993:
987:
986:
983:
982:
974:
973:
967:
964:
963:
955:
954:
948:
942:
941:
936:
931:
927:
926:
916:
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899:
897:
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846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
791:
786:
781:
776:
771:
766:
761:
756:
751:
746:
741:
736:
731:
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710:
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695:
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619:
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569:
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531:
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452:
448:
444:
440:
436:
432:
428:
425:
424:
412:
411:
403:
392:
386:
385:
382:RNA expression
374:
373:
370:
369:
361:
357:
356:
348:
345:
340:
334:
333:
324:
317:
311:
307:
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301:
295:
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286:
285:
273:
272:
269:
268:
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244:
239:
233:
232:
223:
216:
210:
206:
205:
198:
192:
191:
183:
182:
170:
169:
126:
122:
121:
113:
105:
104:
100:
99:
96:
95:
92:
91:
77:
76:
68:
67:
56:
50:
49:
41:
40:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
6295:
6284:
6281:
6279:
6276:
6274:
6271:
6269:
6266:
6265:
6263:
6252:
6247:
6245:
6240:
6238:
6233:
6232:
6226:
6224:
6220:
6217:article is a
6216:
6211:
6208:
6204:
6195:
6190:
6188:
6183:
6181:
6176:
6175:
6169:
6167:
6163:
6159:
6155:
6150:
6147:
6143:
6130:
6127:
6124:
6123:
6120:
6117:
6114:
6113:
6110:
6107:
6104:
6103:
6100:
6097:
6095:
6092:
6090:
6087:
6085:
6082:
6080:
6077:
6075:
6072:
6070:
6067:
6065:
6062:
6060:
6059:Tavolixizumab
6057:
6055:
6052:
6050:
6047:
6045:
6042:
6040:
6037:
6035:
6032:
6030:
6027:
6025:
6022:
6020:
6017:
6015:
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6010:
6007:
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6000:
5997:
5995:
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5990:
5987:
5984:
5983:
5980:
5977:
5975:
5972:
5969:
5968:
5965:
5962:
5960:
5957:
5955:
5952:
5950:
5949:Siva (CD27BP)
5947:
5945:
5942:
5940:
5937:
5935:
5932:
5930:
5927:
5925:
5922:
5919:
5915:
5911:
5910:Ectodysplasin
5908:
5906:
5903:
5901:
5898:
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5886:
5883:
5881:
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5870:
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5812:
5809:
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5779:
5776:
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5771:
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5711:
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5350:
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5299:
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5279:
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5243:
5240:
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5224:
5221:
5220:
5219:
5218:CSF receptors
5215:
5214:
5212:
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4987:
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4360:
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4299:
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4264:
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4000:
3997:
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3992:
3990:
3987:
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3698:
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3141:
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2375:
2371:
2367:
2363:
2358:
2354:
2350:
2346:
2342:
2338:
2334:
2330:
2325:
2324:
2319:
2310:
2304:
2296:
2292:
2287:
2282:
2278:
2274:
2270:
2263:
2260:
2255:
2251:
2247:
2243:
2239:
2235:
2228:
2225:
2220:
2216:
2211:
2206:
2202:
2198:
2194:
2187:
2184:
2179:
2175:
2170:
2165:
2160:
2155:
2151:
2147:
2143:
2139:
2135:
2128:
2125:
2120:
2116:
2111:
2106:
2102:
2098:
2094:
2087:
2084:
2079:
2075:
2070:
2065:
2061:
2057:
2053:
2046:
2043:
2038:
2034:
2029:
2024:
2020:
2016:
2012:
2008:
2004:
1997:
1994:
1989:
1983:
1975:
1971:
1967:
1963:
1959:
1955:
1952:(2): 97–105.
1951:
1947:
1940:
1937:
1932:
1928:
1924:
1920:
1916:
1912:
1905:
1902:
1897:
1893:
1889:
1885:
1881:
1877:
1873:
1869:
1862:
1859:
1854:
1848:
1840:
1836:
1831:
1826:
1822:
1818:
1814:
1810:
1806:
1799:
1796:
1791:
1787:
1782:
1777:
1773:
1769:
1765:
1761:
1757:
1750:
1747:
1735:
1729:
1726:
1721:
1717:
1712:
1707:
1702:
1697:
1693:
1689:
1685:
1678:
1676:
1674:
1672:
1670:
1666:
1661:
1657:
1652:
1647:
1642:
1637:
1633:
1629:
1625:
1618:
1616:
1612:
1607:
1603:
1598:
1593:
1589:
1585:
1581:
1574:
1571:
1566:
1560:
1552:
1548:
1544:
1540:
1536:
1532:
1528:
1524:
1520:
1513:
1510:
1505:
1501:
1495:
1492:
1487:
1483:
1477:
1474:
1470:
1466:
1461:
1459:
1457:
1453:
1449:
1445:
1440:
1438:
1436:
1432:
1425:
1420:
1417:
1414:
1411:
1410:
1409:
1407:
1399:
1397:
1395:
1391:
1387:
1379:
1377:
1374:
1370:
1366:
1362:
1358:
1357:breast cancer
1353:
1347:
1345:
1343:
1338:
1336:
1328:
1323:
1321:
1319:
1315:
1311:
1307:
1303:
1299:
1295:
1291:
1287:
1283:
1275:
1273:
1271:
1267:
1263:
1259:
1255:
1251:
1247:
1243:
1239:
1227:
1222:
1218:
1214:
1211:
1207:
1200:
1198:
1195:
1191:
1187:
1183:
1180:
1176:
1172:
1165:
1163:
1157:
1153:
1150:
1144:
1142:
1136:
1132:
1129:
1125:
1118:
1116:
1110:
1106:
1103:
1097:
1095:
1089:
1085:
1082:
1080:RefSeq (mRNA)
1078:
1071:
1070:
1065:
1061:
1058:
1052:
1051:
1046:
1042:
1039:
1037:
1033:
1026:
1025:
1020:
1016:
1013:
1007:
1006:
1001:
997:
994:
992:
988:
981:
980:
975:
971:
968:
962:
961:
956:
952:
949:
947:
943:
940:
937:
935:
932:
928:
925:
921:
917:
910:
906:
901:
895:
892:
890:
887:
885:
882:
880:
877:
875:
872:
870:
867:
865:
862:
860:
857:
855:
852:
850:
847:
845:
842:
840:
837:
835:
832:
830:
827:
825:
822:
820:
817:
815:
812:
810:
807:
805:
802:
800:
797:
795:
792:
790:
787:
785:
782:
780:
777:
775:
772:
770:
767:
765:
762:
760:
757:
755:
752:
750:
747:
745:
742:
740:
737:
735:
732:
730:
727:
725:
722:
720:
717:
715:
712:
711:
709:
706:
705:
699:
696:
694:
691:
689:
686:
684:
683:membrane raft
681:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
639:
636:
635:
633:
630:
629:
623:
620:
618:
615:
613:
610:
608:
605:
604:
602:
599:
598:
595:
594:Gene ontology
591:
587:
575:
570:
566:
561:
558:
556:
552:
544:
539:
528:
524:
520:
516:
512:
508:
504:
500:
496:
492:
491:
488:
484:
479:
476:
466:
462:
458:
454:
450:
446:
442:
438:
434:
430:
429:
426:
422:
417:
414:
413:
410:
408:
404:
402:
401:
397:
396:
393:
391:
387:
383:
379:
375:
367:
362:
358:
354:
349:
339:
335:
328:
321:
315:
308:
300:
296:
292:
287:
283:
278:
274:
266:
261:
257:
253:
248:
238:
234:
227:
220:
214:
207:
203:
197:
193:
189:
184:
180:
175:
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
131:
123:
118:
111:
106:
101:
90:
88:
84:
78:
73:
70:
69:
65:
62:
55:
51:
46:
42:
38:
33:
30:
19:
6223:expanding it
6215:biochemistry
6212:
6166:expanding it
6158:chromosome 1
6151:
6125:
6115:
6105:
6094:Vorsetuzumab
6019:Enavatuzumab
5985:
5970:
5871:
5834:Pomalidomide
5819:Lenalidomide
5795:
5788:Cannabinoids
5764:
5754:
5748:Pegsunercept
5729:
5713:Ozoralizumab
5679:
5645:
5637:
5609:
5579:
5560:
5406:IL 17 family
4966:
4958:
4950:
4931:
4923:
4915:
4907:
4899:
4891:
4883:
4875:
4867:
4859:
4851:
4843:
4835:
4827:
4808:
4800:
4792:
4784:
4776:
4774:Fas receptor
4768:
4760:
4752:
4744:
4741:
4736:
4719:TNF receptor
4008:
3928:
3906:
3884:
3731:
3694:
3657:
3610:
3580:
3553:
3375:
3281:
3129:
2858:
2610:
2425:cite journal
2390:
2386:
2365:
2361:
2336:
2332:
2303:cite journal
2276:
2272:
2262:
2237:
2233:
2227:
2200:
2196:
2186:
2141:
2137:
2127:
2100:
2096:
2086:
2059:
2055:
2045:
2010:
2006:
1996:
1982:cite journal
1949:
1945:
1939:
1914:
1910:
1904:
1871:
1867:
1861:
1847:cite journal
1812:
1808:
1798:
1763:
1759:
1749:
1737:. Retrieved
1728:
1691:
1687:
1631:
1627:
1587:
1583:
1573:
1559:cite journal
1526:
1522:
1512:
1503:
1494:
1485:
1476:
1403:
1400:Interactions
1383:
1369:renal cancer
1365:colon cancer
1354:
1351:
1339:
1332:
1279:
1253:
1249:
1245:
1241:
1237:
1236:
1159:
1138:
1112:
1091:
1067:
1048:
1022:
1003:
977:
958:
938:
933:
734:human ageing
501:aortic valve
405:
398:
364:144,973,440
351:144,940,033
125:External IDs
80:
29:
6129:Tengonermin
6074:Toralizumab
6069:Tigatuzumab
6064:Teneliximab
6039:Mapatumumab
6034:Lucatumumab
6029:Lexatumumab
6004:Dacetuzumab
5999:Conatumumab
5986:Antibodies:
5852:Thalidomide
5708:Nerelimomab
5680:Antibodies:
5659:Tasonfermin
5649:Plusonermin
5623:Tasonfermin
5613:Plusonermin
5583:Baminercept
5564:Lymphotoxin
4892:(TNFRSF13C)
4884:(TNFRSF13B)
4876:(TNFRSF12A)
4868:(TNFRSF11B)
4860:(TNFRSF11A)
4852:(TNFRSF10D)
4844:(TNFRSF10C)
4836:(TNFRSF10B)
4828:(TNFRSF10A)
2327:Kollias G,
505:granulocyte
431:granulocyte
263:12,209,228
250:12,166,991
103:Identifiers
6262:Categories
6119:Blisibimod
6109:Briobacept
6089:Varlilumab
6084:Utomilumab
6049:Ruplizumab
6024:Iratumumab
6014:Drozitumab
5979:Dulanermin
5974:Ardenermin
5768:Apremilast
5758:Apratastat
5733:Etanercept
5723:Placulumab
5718:Remtolumab
5703:Infliximab
5688:Afelimomab
5683:Adalimumab
5664:TNF (TNFα)
5628:TNF (TNFα)
5593:TNF (TNFα)
5553:LTB (TNFβ)
5545:modulators
4967:(TNFRSF27)
4959:(TNFRSF25)
4951:(TNFRSF21)
4932:(TNFRSF19)
4924:(TNFRSF18)
4916:(TNFRSF17)
4908:(TNFRSF16)
4900:(TNFRSF14)
4785:(TNFRSF6B)
4745:(TNFRSF1B)
4737:(TNFRSF1A)
2493:(see also
1634:: 821310.
1471:, May 2017
1450:, May 2017
1426:References
658:varicosity
459:lymph node
455:right lung
409:(ortholog)
146:HomoloGene
6156:on human
6126:Unsorted:
6054:Tabalumab
6009:Denosumab
5989:Belimumab
5782:green tea
5778:Catechins
5773:Bupropion
5738:Lenercept
5698:Golimumab
5673:Ungrouped
5646:Agonists:
5610:Agonists:
5561:Agonists:
5251:prolactin
4809:(TNFRSF9)
4801:(TNFRSF8)
4793:(TNFRSF7)
4777:(TNFRSF6)
4769:(TNFRSF5)
4761:(TNFRSF4)
4753:(TNFRSF3)
1306:apoptosis
1162:NP_035740
1141:NP_001057
1115:NM_011610
1094:NM_001066
924:Orthologs
154:GeneCards
6079:Urelumab
6044:Oxelumab
5814:LA-SS-Az
5808:turmeric
5804:Curcumin
5792:cannabis
5743:Onercept
5654:Sonermin
5618:Sonermin
5572:β (TNFC)
5568:α (TNFβ)
5480:TGF-beta
4981:JAK-STAT
4929:TAJ/TROY
2487:Proteins
2417:17028114
2374:12371624
2353:12220546
2295:10764746
2254:18671942
2119:11907088
1974:11683986
1966:14743216
1931:10395102
1896:75139844
1888:30856027
1839:29529289
1790:18774186
1720:29892300
1694:: 1170.
1660:24350291
1551:36187863
1467:–
1446:–
1406:interact
1318:Knockout
1286:TNFRSF1A
1276:Function
1250:TNFRSF1B
1210:Wikidata
903:Sources:
643:membrane
509:gastrula
447:appendix
435:monocyte
158:TNFRSF1B
117:TNFRSF1B
35:TNFRSF1B
5476:Ser/Thr
5298:IL22RA2
5294:IL22RA1
5265:Type II
5194:IL12RB2
5190:IL12RB1
5173:IL12RB1
5072:β-chain
5041:IL13RA2
5037:IL13RA1
4999:γ-chain
4295:301–350
4089:251–300
4041:CD240CE
3838:201–250
3522:151–200
3245:101–150
2408:1856025
2219:9162022
2178:8710854
2146:Bibcode
2078:8702708
2037:7639698
2028:1135706
1830:6031046
1781:2574933
1711:5985372
1651:3848079
1606:8702885
1543:2158863
1469:Ensembl
1448:Ensembl
1308:by the
1036:UniProt
991:Ensembl
930:Species
909:QuickGO
688:nucleus
493:decidua
384:pattern
242:1p36.22
142:1314883
110:Aliases
5865:Others
5495:family
5490:TGFBR2
5485:TGFBR1
5439:IL17RE
5434:IL17RD
5429:IL17RC
5424:IL17RB
5419:IL17RA
5396:IL18R1
5349:IFNGR2
5345:IFNGR1
5336:IFNAR2
5332:IFNAR1
5311:IL20RB
5307:IL20RA
5286:IL10RB
5282:IL10RA
5216:other
5146:IL27RA
5137:IL11RA
5105:GM-CSF
4990:Type I
4873:TweakR
4705:CMKLR1
4683:CX3CR1
4302:CD300A
4261:CDw293
4046:CD240D
3907:CD213a
3885:CDw210
3850:CD202b
3824:CDw199
3819:CDw198
3473:CD140b
2905:51–100
2452:(MeSH)
2415:
2405:
2372:
2351:
2293:
2252:
2217:
2176:
2166:
2117:
2076:
2035:
2025:
1972:
1964:
1929:
1894:
1886:
1837:
1827:
1788:
1778:
1718:
1708:
1658:
1648:
1604:
1549:
1541:
1408:with:
1394:allele
1367:, and
1348:Cancer
1342:sTNFR2
1298:c-IAP2
1294:c-IAP1
1254:CD120b
1252:) and
1196:search
1194:PubMed
1069:P25119
1050:P20333
946:Entrez
555:BioGPS
521:spleen
443:spleen
134:191191
6213:This
6160:is a
5847:TCB-2
5638:TNFR2
5602:TNFR1
5464:CSF1R
5392:IL18R
5385:IL1R2
5380:IL1R1
5316:IL28R
5303:IL20R
5290:IL22R
5278:IL10R
5228:G-CSF
5210:Other
5199:IL23R
5186:IL12R
5163:CNTFR
5128:IL6RA
5115:gp130
5098:IL5RA
5089:IL3RA
5060:IL21R
5050:IL7RA
5033:IL13R
5024:IL15R
5020:IL2RB
5016:IL2RA
4964:EDA2R
4941:21-27
4889:BAFFR
4818:11-20
4806:CD137
4758:CD134
4742:TNFR2
4734:TNFR1
4700:CCBP2
4679:CX3C
4673:Other
4664:CXCR7
4659:CXCR6
4654:CXCR5
4649:CXCR4
4644:CXCR3
4637:CXCR2
4632:CXCR1
4609:CCR10
4569:CCRL2
4559:CCRL1
4537:GPCRs
4482:CD350
4477:CD349
4472:CD344
4467:CD340
4462:CD339
4457:CD338
4452:CD337
4447:CD336
4442:CD335
4437:CD334
4432:CD333
4427:CD332
4422:CD331
4417:CD329
4412:CD328
4407:CD327
4402:CD326
4397:CD325
4392:CD324
4387:CD322
4382:CD321
4377:CD320
4372:CD318
4367:CD317
4362:CD316
4357:CD315
4352:CD314
4347:CD312
4342:CD309
4337:CD307
4332:CD306
4327:CD305
4322:CD304
4317:CD303
4312:CD302
4307:CD301
4286:CD299
4281:CD298
4276:CD297
4271:CD295
4266:CD294
4256:CD292
4251:CD290
4246:CD289
4241:CD288
4236:CD286
4231:CD284
4226:CD283
4221:CD282
4216:CD281
4211:CD280
4206:CD279
4201:CD278
4196:CD276
4191:CD275
4186:CD274
4181:CD273
4176:CD272
4171:CD271
4166:CD269
4161:CD268
4156:CD267
4151:CD266
4146:CD265
4141:CD264
4136:CD263
4131:CD262
4126:CD261
4121:CD258
4116:CD257
4111:CD256
4106:CD254
4101:CD253
4096:CD252
4080:CD249
4075:CD248
4071:CD247
4066:CD246
4061:CD244
4056:CD243
4051:CD241
4036:CD239
4031:CD238
4026:CD236
4009:CD235
4004:CD234
3999:CD233
3994:CD230
3989:CD229
3984:CD228
3979:CD227
3974:CD226
3969:CD225
3964:CD224
3959:CD223
3954:CD222
3949:CD221
3944:CD220
3929:CD218
3924:CD217
3902:CD212
3880:CD209
3875:CD208
3870:CD207
3865:CD206
3860:CD205
3855:CD204
3845:CD201
3829:CD200
3814:CD197
3809:CD196
3804:CD195
3799:CD194
3794:CD193
3789:CD192
3784:CD191
3779:CD186
3774:CD185
3769:CD184
3764:CD183
3759:CD182
3754:CD181
3749:CD180
3732:CD179
3727:CD178
3722:CD177
3717:CD174
3695:CD172
3690:CD171
3685:CD170
3680:CD169
3675:CD168
3658:CD167
3653:CD166
3648:CD164
3643:CD163
3638:CD162
3633:CD161
3628:CD160
3611:CD159
3581:CD158
3576:CD157
3554:CD156
3549:CD155
3544:CD154
3539:CD153
3534:CD152
3529:CD151
3513:CD150
3508:CD148
3503:CD147
3498:CD146
3493:CD144
3488:CD143
3483:CD142
3478:CD141
3468:CD138
3463:CD137
3458:CD136
3453:CD135
3448:CD134
3443:CD133
3438:CD132
3433:CD131
3428:CD130
3423:CD129
3418:CD127
3413:CD126
3408:CD125
3403:CD124
3398:CD123
3393:CD122
3376:CD121
3359:CD120
3354:CD119
3349:CD118
3344:CD117
3339:CD116
3334:CD115
3329:CD114
3324:CD113
3319:CD112
3314:CD111
3309:CD110
3304:CD109
3299:CD108
3282:CD107
3277:CD106
3272:CD105
3267:CD104
3262:CD103
3257:CD102
3252:CD101
3236:CD100
2169:38654
1970:S2CID
1892:S2CID
1739:8 May
1547:S2CID
1419:TTRAP
1415:, and
1413:TRAF2
1314:TRAF2
1242:TNFR2
979:21938
939:Mouse
934:Human
905:Amigo
513:blood
439:blood
407:Mouse
400:Human
347:Start
282:Mouse
246:Start
179:Human
18:TNFR2
6219:stub
6162:stub
6154:gene
5890:CAML
5842:-DOI
5414:IL17
5328:-α/β
5158:LIFR
5153:OSMR
5094:IL5R
5085:IL3R
5055:IL9R
5046:IL7R
5029:IL4R
5012:IL2R
4921:GITR
4913:BCMA
4905:NGFR
4897:HVEM
4881:TACI
4857:RANK
4849:DcR2
4841:DcR1
4798:CD30
4790:CD27
4782:DcR3
4766:CD40
4750:LTBR
4727:1-10
4693:XCR1
4627:IL-8
4604:CCR9
4599:CCR8
4594:CCR7
4589:CCR6
4584:CCR5
4579:CCR4
4574:CCR3
4564:CCR2
4555:CCR1
3231:CD99
3226:CD98
3221:CD97
3216:CD96
3211:CD95
3206:CD94
3201:CD93
3196:CD92
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