3755:
475:>10) and the only one that shows neurotoxicity. The β complex is neutral and can be separated into two isoforms. β1 and β2 are interchangeable but differ slightly in amino acid composition. The γ complex contains 135 amino acid residues which are cross linked by 8 disulfide bridges. It is very acidic due to 4
647:
produced by CSL Ltd in 1956 in
Australia on the basis of immunised horse plasma. After being bitten the majority of patients will develop systemic envenoming of which clinical evidence is usually present within two hours. This effect can be delayed by applying first aid measures, like immobilization.
582:
A similar experiment has been done refocusing on the neural compounds. 24 hours after the injection the innervation was compromised to the extent of being unable to identify intact axons. This showed that taipoxin like toxins lead to the depletion of transmitters from the nerve terminals and lead to
459:
consisting of three subunits of α, β and γ monomers in a 1:1:1 ratio, also called the A, B and C homologous subunits. These subunits are equally distributed across the structure, and together the three-dimensional structures of these three monomers form a shared core of three α-helices, a Ca binding
566:
In the beginning taipoxin was thought to be only neurotoxic. Studies showed an increase in acetylcholine release, indicating a presynaptic activity. Further experiments showed that
Taipoxin inhibited the responses to electrical stimuli greater than the reaction to additionally administered
487:. It also boosts the specificity on the target and could be involved in the binding of the alpha unit. The whole complex is slightly acidic with a pH(I) of 5, but under a lower pH and/or high ionic strength the subunits dissociate.
567:
acetylcholine. This led to the conclusion that taipoxin has pre- and postsynaptic effects. Additional to the increased acetylcholine release it inhibits the vesicular recycling. More recent studies showed that the toxin has a
1733:
Megighian A, Rigoni M, Caccin P, Zordan MA, Montecucco C (April 2007). "A lysolecithin/fatty acid mixture promotes and then blocks neurotransmitter release at the
Drosophila melanogaster larval neuromuscular junction".
634:
activity and toxicity, as the pharmacokinetics and the membrane binding properties are more important. A more specific membrane binding would lead to accumulation of taipoxin in the plasma membranes of motor-neurons.
720:"Taipoxin, an extremely potent presynaptic neurotoxin from the venom of the australian snake taipan (Oxyuranus s. scutellatus). Isolation, characterization, quaternary structure and pharmacological properties"
2274:
1615:
Rigoni M, Caccin P, Gschmeissner S, Koster G, Postle AD, Rossetto O, et al. (December 2005). "Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures".
1085:"Taipoxin, an extremely potent presynaptic snake venom neurotoxin. Elucidation of the primary structure of the acidic carbohydrate-containing taipoxin-subunit, a prophospholipase homolog"
591:
release in depolarizing cells by disassembling F-actin in the cytoskeletal barrier. This could lead to a vesicle redistribution promoting immediate access into the subplasmalemmal area.
594:
More research studies have found potential binding partners of taipoxin, which would give more insight into how taipoxin is transported to the nerve terminals and intramuscular axons.
526:
s from the more potent viperid venoms which causes inflammatory exudate's are grouped into class II. However most snake venoms are capable of more than one toxic activity, such as
1445:
Neco P, Rossetto O, Gil A, Montecucco C, Gutiérrez LM (April 2003). "Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells".
1531:"Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin-associated calcium-binding protein 49"
1490:"Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2"
874:
Davidson FF, Dennis EA (September 1990). "Evolutionary relationships and implications for the regulation of phospholipase A2 from snake venom to human secreted forms".
2400:
579:
potency, which is similar to the potency of notexin. Even so, the full potential of the raw toxin is only reached by the combination of the α and γ subunits.
1124:
Lomonte B, Tarkowski A, Hanson LA (November 1994). "Broad cytolytic specificity of myotoxin II, a lysine-49 phospholipase A2 of
Bothrops asper snake venom".
3789:
3347:
389:) toxins, which inhibit/complete block the release of the motor transmitter acetylcholine and lead to death by paralysis of the respiratory muscles (
1231:
Hyatt MC, Russell JA (October 1981). "Effects of beta-bungarotoxin and taipoxin on contractions of canine airways caused by nerve stimulation".
479:, which might be important for complex formation. The gamma subunit also seems to function as a protector of the alpha complex, preventing fast
1838:
443:. However it is thought that under strict evolution selection pressures of prey immobilisation and therefore extended feeding lead to the PLA
2557:
447:
enzyme losing its so called pancreatic loop and mutations for the toxin binding with pre-synaptic membranes of motor neuron end plates.
1032:
1402:
Harris JB, Grubb BD, Maltin CA, Dixon R (February 2000). "The neurotoxicity of the venom phospholipases A(2), notexin and taipoxin".
2686:
2678:
1591:
930:
Montecucco C, Rossetto O (June 2008). "On the quaternary structure of taipoxin and textilotoxin: the advantage of being multiple".
2682:
2570:
2422:
2656:
2785:
1777:
Kuruppu S, Chaisakul J, Smith AI, Hodgson WC (April 2014). "Inhibition of presynaptic neurotoxins in taipan venom by suramin".
1207:
1048:
Fletcher JE, Jiang MS (December 1995). "Presynaptically acting snake venom phospholipase A2 enzymes attack unique substrates".
294:
203:
112:
33:
1271:"Myotoxic activity of the crude venom and the principal neurotoxin, taipoxin, of the Australian taipan, Oxyuranus scutellatus"
3475:
3432:
2121:
761:"Cross-Neutralisation of In Vitro Neurotoxicity of Asian and Australian Snake Neurotoxins and Venoms by Different Antivenoms"
2937:
2581:
2576:
606:
toxins are often measured with their ability to cut short chain phospholipids or phospholipids-analogues. For taipoxin PLA
555:
575:
formation and muscle degeneration. The study also supports the findings by
Fohlman, that the α subunit yields the PLA
2696:
1987:
558:. In addition to taipoxin, the venom consists of many different components, responsible for the complex symptoms.
1831:
2986:
480:
970:
Alape-Girón A, Persson B, Cederlund E, Flores-Díaz M, Gutiérrez JM, Thelestam M, et al. (January 1999).
2770:
2758:
2562:
2551:
1318:
Harris JB, MacDonell CA (1981-01-01). "Phospholipase A2 activity of notexin and its role in muscle damage".
2353:
2333:
2742:
2500:
1632:
413:
3784:
3593:
3228:
2589:
2156:
522:
s from pancreatic secretions, bee venom or the weak elapid venoms are grouped into class I, whereas PLA
510:
toxins are categorized into three classes. These classes are also an indication of the toxicity of PLA
3779:
2780:
2415:
2348:
2343:
1824:
1624:
883:
1637:
810:
3758:
2219:
688:
499:
1159:
Gutiérrez JM, Lomonte B (November 1995). "Phospholipase A2 myotoxins from
Bothrops snake venoms".
683:
3696:
2866:
2824:
2701:
2532:
2338:
2299:
1802:
1759:
1715:
1666:
1650:
1470:
1427:
1001:
907:
856:
435:
enzymes. The venom still functions with the almost identical multi-disulphide-bridged protein PLA
405:
587:
taipoxin showed the ability to enter the cells via Ca independent mechanisms. There it enhanced
3701:
3645:
2932:
2161:
1794:
1751:
1707:
1658:
1597:
1587:
1552:
1511:
1462:
1419:
1384:
1335:
1300:
1248:
1186:
1141:
1106:
1065:
1028:
993:
947:
899:
848:
792:
741:
678:
673:
630:
as it consist out of 3 enzymatic domains/subunits. However no correlation was made between PLA
472:
464:
219:
128:
3640:
3458:
3064:
2980:
2922:
2728:
2254:
2249:
2244:
2239:
2234:
2229:
2224:
1921:
1786:
1743:
1697:
1642:
1579:
1542:
1501:
1454:
1411:
1374:
1366:
1327:
1290:
1282:
1240:
1176:
1168:
1133:
1096:
1057:
983:
939:
891:
838:
782:
772:
731:
611:
429:
401:
379:
3723:
3628:
3223:
2878:
2775:
2620:
2595:
2480:
2408:
2384:
2374:
2369:
2151:
1954:
1946:
584:
456:
378:
or also known as the common taipan. Taipoxin like many other pre-synaptic neurotoxins are
334:
255:
164:
73:
1628:
887:
3665:
3213:
3153:
2976:
2968:
2715:
2669:
2438:
2389:
2379:
2204:
1931:
1379:
1354:
1295:
1286:
1270:
787:
760:
736:
719:
551:
397:
372:
1370:
3773:
3741:
note: some toxins are produced by lower species and pass through intermediate species
3655:
3598:
3352:
3315:
3263:
3208:
3193:
3069:
3029:
2972:
2766:
2615:
2538:
2136:
2116:
2088:
2055:
2035:
1959:
1881:
1861:
1458:
1331:
1244:
1172:
1137:
1101:
1084:
1061:
988:
971:
843:
826:
649:
588:
535:
531:
498:
toxin is Ca dependent for hydrolysing fatty acyl ester bonds at the sn-2 position of
1806:
1719:
1686:"Reversible skeletal neuromuscular paralysis induced by different lysophospholipids"
1670:
860:
3718:
3708:
3691:
3660:
3608:
3572:
3531:
3485:
3422:
3325:
3248:
3183:
3018:
3014:
3010:
2996:
2810:
2646:
2443:
1916:
1911:
1876:
1763:
1578:. Methods in Molecular Biology. Vol. 284. Methods Mol. Biol. pp. 229–42.
1474:
1431:
1005:
911:
527:
1702:
1685:
943:
1747:
3681:
3635:
3623:
3480:
3427:
3377:
3283:
3278:
3268:
3233:
3218:
3084:
2752:
2723:
2543:
2521:
2458:
2448:
2279:
2186:
2126:
2070:
2045:
2015:
2002:
1936:
1926:
1901:
1583:
668:
539:
484:
476:
344:
265:
174:
83:
571:
effect as well. The injection of taipoxin into the hind limbs of rats leads to
3713:
3650:
3567:
3545:
3490:
3453:
3397:
3367:
3357:
3298:
3288:
3273:
3258:
3253:
3238:
3158:
3143:
3059:
3049:
3044:
3034:
3001:
2691:
2651:
2468:
2463:
2284:
2194:
2141:
2030:
2025:
2020:
1982:
1977:
1969:
1896:
1891:
1847:
1790:
364:
310:
231:
140:
49:
1547:
1530:
502:. Depending on disulphide bridge positions and lengths of C-termini these PLA
3618:
3613:
3603:
3583:
3526:
3516:
3511:
3470:
3382:
3198:
3178:
3168:
3128:
3123:
3103:
3074:
3024:
3006:
2959:
2951:
2858:
2842:
2453:
2131:
2108:
2093:
2080:
2065:
2050:
2010:
1992:
1906:
1886:
1646:
644:
468:
1798:
1755:
1711:
1684:
Caccin P, Rigoni M, Bisceglie A, Rossetto O, Montecucco C (November 2006).
1662:
1601:
1515:
1506:
1489:
1466:
1423:
1415:
1388:
951:
852:
796:
660:
Similar to taipoxin are toxins with different subunits of the PLA domains:
393:). It is the most lethal neurotoxin isolated from any snake venom to date.
1556:
1339:
1304:
1252:
1190:
1145:
1069:
997:
903:
777:
3521:
3501:
3412:
3407:
3372:
3362:
3337:
3293:
3243:
3188:
3163:
3148:
3113:
3108:
3039:
2991:
2964:
2910:
2838:
2832:
2818:
2804:
2795:
2491:
2171:
2146:
2098:
2040:
1871:
1866:
1110:
745:
568:
390:
360:
315:
236:
145:
54:
3676:
3138:
3133:
3118:
3079:
3054:
2891:
2871:
2511:
2289:
2264:
2259:
2199:
2176:
2166:
2060:
1654:
1355:"Nerve terminal damage by beta-bungarotoxin: its clinical significance"
1181:
895:
663:
825:
Rossetto O, Morbiato L, Caccin P, Rigoni M, Montecucco C (June 2006).
224:
133:
3443:
3417:
3387:
3203:
2905:
2886:
2634:
2269:
460:
site and a hydrophobic channel to which the fatty acyl chains binds.
440:
3392:
3308:
3303:
3173:
3094:
2433:
2317:
2214:
2209:
1529:
Dodds DC, Omeis IA, Cushman SJ, Helms JA, Perin MS (August 1997).
572:
368:
972:"Elapid venom toxins: multiple recruitments of ancient scaffolds"
3557:
3465:
2312:
2307:
2404:
1820:
583:
the degeneration of nerve terminal and intramuscular axons. In
3402:
1816:
718:
Fohlman J, Eaker D, Karlsoon E, Thesleff S (September 1976).
2275:
Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)
1488:
Kirkpatrick LL, Matzuk MM, Dodds DC, Perin MS (June 2000).
439:
scaffold, which causes the hydrolytic mechanism of the
1570:
3674:
3581:
3555:
3544:
3499:
3441:
3335:
3324:
3093:
2950:
2921:
2857:
2794:
2741:
2714:
2667:
2633:
2606:
2519:
2510:
2499:
2490:
2479:
2362:
2326:
2298:
2185:
2107:
2079:
2001:
1968:
1945:
1854:
340:
330:
325:
309:
301:
289:
284:
279:
261:
251:
246:
230:
218:
210:
198:
193:
188:
170:
160:
155:
139:
127:
119:
107:
102:
97:
79:
69:
64:
48:
40:
28:
23:
18:
610:activity was set on 0.4 mmol/min/mg, and the
759:Silva A, Hodgson WC, Isbister GK (October 2016).
652:whose effect is also inhibited by the antivenom.
648:Additional to neurotoxins taipan venom contains
550:Taipoxin can be purified from the venom of the
2416:
1832:
713:
711:
709:
707:
705:
8:
1083:Fohlman J, Lind P, Eaker D (December 1977).
676:is a heterodimer from Chinese banded krait (
3552:
3332:
2639:
2516:
2507:
2496:
2487:
2423:
2409:
2401:
1839:
1825:
1817:
322:
243:
152:
61:
3348:Androctonus australis hector insect toxin
1701:
1636:
1546:
1505:
1378:
1294:
1180:
1100:
987:
842:
786:
776:
735:
404:; comprising 1:1:1 α, β and γ monomers.
701:
428:toxins have evolved from the digestive
276:
185:
94:
15:
1353:Dixon RW, Harris JB (February 1999).
1264:
1262:
1202:
1200:
602:The toxicity of Taipoxin or other PLA
412:) for mice is around 1–2 μg/kg (
7:
965:
963:
961:
925:
923:
921:
614:(K) of taipoxin would be equal to: K
400:of the heterotrimer is about 46,000
1535:The Journal of Biological Chemistry
1494:The Journal of Biological Chemistry
827:"Presynaptic enzymatic neurotoxins"
471:. The alpha subunit is very basic (
463:The α and β complex consist of 120
2702:Staphylococcal Enterotoxin B (SEB)
1287:10.1111/j.1476-5381.1982.tb09191.x
737:10.1111/j.1432-1033.1976.tb10833.x
14:
1359:The American Journal of Pathology
1269:Harris JB, Maltin CA (May 1982).
3790:Acetylcholine release inhibitors
3754:
3753:
1459:10.1046/j.1471-4159.2003.01682.x
989:10.1046/j.1432-1327.1999.00021.x
976:European Journal of Biochemistry
844:10.1111/j.1471-4159.2006.03965.x
724:European Journal of Biochemistry
2786:Extracellular adenylate cyclase
1275:British Journal of Pharmacology
2122:Tetramethylenedisulfotetramine
876:Journal of Molecular Evolution
643:The treatment of choice is an
1:
2938:Fibronectin binding protein A
1703:10.1016/j.febslet.2006.10.039
1576:Signal Transduction Protocols
1371:10.1016/S0002-9440(10)65291-1
944:10.1016/j.toxicon.2008.03.020
556:gel filtration chromatography
1748:10.1016/j.neulet.2007.01.040
1332:10.1016/0041-0101(81)90046-5
1245:10.1016/0024-3205(81)90185-5
1173:10.1016/0041-0101(95)00085-z
1138:10.1016/0041-0101(94)90408-1
1102:10.1016/0014-5793(77)80726-6
1062:10.1016/0041-0101(95)00108-5
467:which are cross linked by 7
2679:Staphylococcus aureus alpha
2657:Panton–Valentine leukocidin
686:is a pentamer from eastern
367:that was isolated from the
3806:
2697:Toxic shock syndrome toxin
3749:
3736:
3594:(+)-Allopumiliotoxin 267A
2642:
1791:10.1007/s12640-013-9426-z
1584:10.1385/1-59259-816-1:229
1447:Journal of Neurochemistry
831:Journal of Neurochemistry
321:
242:
151:
60:
2987:beta-Nitropropionic acid
1548:10.1074/jbc.272.34.21488
2771:Heat-labile enterotoxin
2762:heat-stable enterotoxin
2327:Cholinergic neurotoxins
1647:10.1126/science.1120640
485:proteolytic degradation
2880:Bacillus thuringiensis
1779:Neurotoxicity Research
1507:10.1074/jbc.M002254200
1416:10.1006/exnr.1999.7275
1404:Experimental Neurology
500:glycerol-phospholipids
424:Taipoxin and other PLA
414:subcutaneous injection
2354:Hemicholinium mustard
2334:Acetylcholine mustard
2157:Chlorophenylsilatrane
1027:. Chichester: Wiley.
1021:Venom Phospholipase A
778:10.3390/toxins8100302
679:Bungarus multicinctus
376:Oxyuranus scutellatus
295:Oxyuranus scutellatus
204:Oxyuranus scutellatus
113:Oxyuranus scutellatus
34:Oxyuranus scutellatus
2781:Pseudomonas exotoxin
2349:Ethylcholine mustard
1736:Neuroscience Letters
477:sialic acid residues
2300:Bicyclic phosphates
1922:Spooky toxin (SsTx)
1629:2005Sci...310.1678R
888:1990JMolE..31..228D
689:Pseudonaja textilis
562:Mechanism of action
465:amino acid residues
189:Taipoxin subunit β2
98:Taipoxin subunit β1
3697:Alpha-Bungarotoxin
2867:Lipopolysaccharide
2825:Pore-forming toxin
1208:"Taipan Antivenom"
896:10.1007/BF02109500
666:is a monomer from
406:Median lethal dose
280:Taipoxin subunit γ
19:Taipoxin subunit α
3767:
3766:
3732:
3731:
3702:Beta-Bungarotoxin
3646:Pumiliotoxin 251D
3540:
3539:
2946:
2945:
2933:Clumping factor A
2853:
2852:
2737:
2736:
2710:
2709:
2629:
2628:
2398:
2397:
2162:Sulfuryl fluoride
1623:(5754): 1678–80.
669:Notechis scutatus
546:Isolation process
469:disulfide bridges
354:
353:
350:
349:
275:
274:
271:
270:
184:
183:
180:
179:
93:
92:
89:
88:
3797:
3757:
3756:
3685:
3641:Histrionicotoxin
3587:
3561:
3553:
3505:
3459:Alpha-latrotoxin
3447:
3341:
3333:
3065:Sterigmatocystin
3017:, Fumonisin B3,
2981:epsilon-amanitin
2900:B. thuringiensis
2729:Diphtheria toxin
2672:
2640:
2609:
2525:
2517:
2508:
2497:
2488:
2425:
2418:
2411:
2402:
1841:
1834:
1827:
1818:
1811:
1810:
1774:
1768:
1767:
1730:
1724:
1723:
1705:
1681:
1675:
1674:
1640:
1612:
1606:
1605:
1567:
1561:
1560:
1550:
1541:(34): 21488–94.
1526:
1520:
1519:
1509:
1500:(23): 17786–92.
1485:
1479:
1478:
1442:
1436:
1435:
1399:
1393:
1392:
1382:
1350:
1344:
1343:
1315:
1309:
1308:
1298:
1266:
1257:
1256:
1228:
1222:
1221:
1219:
1218:
1204:
1195:
1194:
1184:
1156:
1150:
1149:
1121:
1115:
1114:
1104:
1080:
1074:
1073:
1045:
1039:
1038:
1019:Kini RM (1997).
1016:
1010:
1009:
991:
967:
956:
955:
927:
916:
915:
871:
865:
864:
846:
822:
816:
807:
801:
800:
790:
780:
756:
750:
749:
739:
715:
612:binding constant
585:chromaffin cells
323:
297:
277:
244:
206:
186:
153:
115:
95:
62:
36:
16:
3805:
3804:
3800:
3799:
3798:
3796:
3795:
3794:
3770:
3769:
3768:
3763:
3745:
3728:
3724:Cardiotoxin III
3680:
3675:
3670:
3582:
3577:
3556:
3548:
3536:
3500:
3495:
3442:
3437:
3336:
3328:
3320:
3224:Resiniferatoxin
3089:
2942:
2924:
2917:
2882:delta endotoxin
2849:
2790:
2776:Pertussis toxin
2744:
2733:
2706:
2668:
2663:
2625:
2621:Listeriolysin O
2607:
2602:
2520:
2502:
2482:
2475:
2429:
2399:
2394:
2375:Dimethylmercury
2370:Dimethylcadmium
2358:
2344:Choline mustard
2322:
2294:
2181:
2152:Phenylsilatrane
2103:
2075:
1997:
1964:
1955:Botulinum toxin
1941:
1850:
1845:
1815:
1814:
1776:
1775:
1771:
1732:
1731:
1727:
1696:(27): 6317–21.
1683:
1682:
1678:
1638:10.1.1.817.8280
1614:
1613:
1609:
1594:
1573:
1569:
1568:
1564:
1528:
1527:
1523:
1487:
1486:
1482:
1444:
1443:
1439:
1401:
1400:
1396:
1352:
1351:
1347:
1317:
1316:
1312:
1268:
1267:
1260:
1230:
1229:
1225:
1216:
1214:
1206:
1205:
1198:
1167:(11): 1405–24.
1158:
1157:
1153:
1132:(11): 1359–69.
1123:
1122:
1118:
1082:
1081:
1077:
1056:(12): 1565–76.
1047:
1046:
1042:
1035:
1024:
1018:
1017:
1013:
982:(1–2): 225–34.
969:
968:
959:
929:
928:
919:
873:
872:
868:
824:
823:
819:
808:
804:
758:
757:
753:
717:
716:
703:
698:
658:
641:
633:
629:
625:
621:
617:
609:
605:
600:
578:
564:
548:
530:, myotoxicity,
525:
521:
517:
513:
509:
505:
497:
493:
490:Just as the PLA
481:renal clearance
457:ternary complex
453:
446:
438:
433:
427:
422:
411:
388:
383:
380:phospholipase A
293:
202:
111:
32:
12:
11:
5:
3803:
3801:
3793:
3792:
3787:
3782:
3772:
3771:
3765:
3764:
3762:
3761:
3750:
3747:
3746:
3744:
3743:
3737:
3734:
3733:
3730:
3729:
3727:
3726:
3721:
3716:
3711:
3706:
3705:
3704:
3699:
3688:
3686:
3672:
3671:
3669:
3668:
3666:Zetekitoxin AB
3663:
3658:
3653:
3648:
3643:
3638:
3633:
3632:
3631:
3626:
3621:
3616:
3611:
3601:
3596:
3590:
3588:
3579:
3578:
3576:
3575:
3570:
3564:
3562:
3550:
3542:
3541:
3538:
3537:
3535:
3534:
3529:
3524:
3519:
3514:
3508:
3506:
3497:
3496:
3494:
3493:
3488:
3483:
3478:
3473:
3468:
3463:
3462:
3461:
3450:
3448:
3439:
3438:
3436:
3435:
3430:
3425:
3420:
3415:
3410:
3405:
3400:
3395:
3390:
3385:
3380:
3375:
3370:
3365:
3360:
3355:
3350:
3344:
3342:
3330:
3322:
3321:
3319:
3318:
3313:
3312:
3311:
3306:
3296:
3291:
3286:
3281:
3276:
3271:
3266:
3261:
3256:
3251:
3246:
3241:
3236:
3231:
3226:
3221:
3216:
3214:Pseudaconitine
3211:
3206:
3201:
3196:
3191:
3186:
3181:
3176:
3171:
3166:
3161:
3156:
3154:Djenkolic acid
3151:
3146:
3141:
3136:
3131:
3126:
3121:
3116:
3111:
3106:
3100:
3098:
3091:
3090:
3088:
3087:
3082:
3077:
3072:
3067:
3062:
3057:
3052:
3047:
3042:
3037:
3032:
3027:
3022:
3004:
2999:
2994:
2989:
2984:
2977:gamma-amanitin
2969:alpha-amanitin
2962:
2956:
2954:
2948:
2947:
2944:
2943:
2941:
2940:
2935:
2929:
2927:
2919:
2918:
2916:
2915:
2914:
2913:
2908:
2896:
2895:
2894:
2889:
2876:
2875:
2874:
2863:
2861:
2855:
2854:
2851:
2850:
2848:
2847:
2846:
2845:
2829:
2828:
2827:
2815:
2814:
2813:
2800:
2798:
2792:
2791:
2789:
2788:
2783:
2778:
2773:
2764:
2756:
2749:
2747:
2739:
2738:
2735:
2734:
2732:
2731:
2726:
2720:
2718:
2716:Actinomycetota
2712:
2711:
2708:
2707:
2705:
2704:
2699:
2694:
2689:
2675:
2673:
2670:Staphylococcus
2665:
2664:
2662:
2661:
2660:
2659:
2649:
2643:
2637:
2631:
2630:
2627:
2626:
2624:
2623:
2618:
2612:
2610:
2604:
2603:
2601:
2600:
2599:
2598:
2586:
2585:
2584:
2579:
2567:
2566:
2565:
2560:
2548:
2547:
2546:
2541:
2528:
2526:
2514:
2505:
2494:
2485:
2477:
2476:
2474:
2473:
2472:
2471:
2466:
2461:
2456:
2451:
2446:
2441:
2430:
2428:
2427:
2420:
2413:
2405:
2396:
2395:
2393:
2392:
2390:Tetraethyllead
2387:
2382:
2380:Toxopyrimidine
2377:
2372:
2366:
2364:
2360:
2359:
2357:
2356:
2351:
2346:
2341:
2336:
2330:
2328:
2324:
2323:
2321:
2320:
2315:
2310:
2304:
2302:
2296:
2295:
2293:
2292:
2287:
2282:
2277:
2272:
2267:
2262:
2257:
2252:
2247:
2242:
2237:
2232:
2227:
2222:
2217:
2212:
2207:
2205:Novichok agent
2202:
2197:
2191:
2189:
2183:
2182:
2180:
2179:
2174:
2169:
2164:
2159:
2154:
2149:
2144:
2139:
2134:
2129:
2124:
2119:
2113:
2111:
2105:
2104:
2102:
2101:
2096:
2091:
2085:
2083:
2077:
2076:
2074:
2073:
2068:
2063:
2058:
2053:
2048:
2043:
2038:
2033:
2028:
2023:
2018:
2013:
2007:
2005:
1999:
1998:
1996:
1995:
1990:
1985:
1980:
1974:
1972:
1966:
1965:
1963:
1962:
1957:
1951:
1949:
1943:
1942:
1940:
1939:
1934:
1932:Zetekitoxin AB
1929:
1924:
1919:
1914:
1909:
1904:
1899:
1894:
1889:
1884:
1879:
1874:
1869:
1864:
1858:
1856:
1852:
1851:
1846:
1844:
1843:
1836:
1829:
1821:
1813:
1812:
1769:
1725:
1676:
1607:
1592:
1571:
1562:
1521:
1480:
1437:
1394:
1345:
1310:
1258:
1239:(17): 1755–9.
1223:
1212:www.csl.com.au
1196:
1151:
1116:
1075:
1040:
1034:978-0471961895
1033:
1022:
1011:
957:
917:
866:
837:(6): 1534–45.
817:
809:Alomone labs:
802:
751:
700:
699:
697:
694:
674:β-bungarotoxin
657:
656:Similar toxins
654:
650:anticoagulants
640:
637:
631:
627:
623:
619:
615:
607:
603:
599:
596:
576:
563:
560:
552:coastal taipan
547:
544:
532:neuro-toxicity
523:
519:
515:
511:
507:
503:
495:
494:enzyme the PLA
491:
455:Taipoxin is a
452:
449:
444:
436:
431:
425:
421:
418:
409:
398:molecular mass
386:
381:
373:coastal taipan
352:
351:
348:
347:
342:
338:
337:
332:
328:
327:
319:
318:
313:
307:
306:
303:
299:
298:
291:
287:
286:
282:
281:
273:
272:
269:
268:
263:
259:
258:
253:
249:
248:
240:
239:
234:
228:
227:
222:
216:
215:
212:
208:
207:
200:
196:
195:
191:
190:
182:
181:
178:
177:
172:
168:
167:
162:
158:
157:
149:
148:
143:
137:
136:
131:
125:
124:
121:
117:
116:
109:
105:
104:
100:
99:
91:
90:
87:
86:
81:
77:
76:
71:
67:
66:
58:
57:
52:
46:
45:
42:
38:
37:
30:
26:
25:
21:
20:
13:
10:
9:
6:
4:
3:
2:
3802:
3791:
3788:
3786:
3783:
3781:
3778:
3777:
3775:
3760:
3752:
3751:
3748:
3742:
3739:
3738:
3735:
3725:
3722:
3720:
3717:
3715:
3712:
3710:
3707:
3703:
3700:
3698:
3695:
3694:
3693:
3690:
3689:
3687:
3683:
3678:
3673:
3667:
3664:
3662:
3659:
3657:
3656:Samandaridine
3654:
3652:
3649:
3647:
3644:
3642:
3639:
3637:
3634:
3630:
3629:Marinobufagin
3627:
3625:
3622:
3620:
3617:
3615:
3612:
3610:
3607:
3606:
3605:
3602:
3600:
3599:Batrachotoxin
3597:
3595:
3592:
3591:
3589:
3585:
3580:
3574:
3571:
3569:
3566:
3565:
3563:
3559:
3554:
3551:
3547:
3543:
3533:
3530:
3528:
3525:
3523:
3520:
3518:
3515:
3513:
3510:
3509:
3507:
3503:
3498:
3492:
3489:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3460:
3457:
3456:
3455:
3452:
3451:
3449:
3445:
3440:
3434:
3431:
3429:
3426:
3424:
3421:
3419:
3416:
3414:
3411:
3409:
3406:
3404:
3401:
3399:
3396:
3394:
3391:
3389:
3386:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3353:Charybdotoxin
3351:
3349:
3346:
3345:
3343:
3339:
3334:
3331:
3327:
3323:
3317:
3314:
3310:
3307:
3305:
3302:
3301:
3300:
3297:
3295:
3292:
3290:
3287:
3285:
3282:
3280:
3277:
3275:
3272:
3270:
3267:
3265:
3264:Solauricidine
3262:
3260:
3257:
3255:
3252:
3250:
3247:
3245:
3242:
3240:
3237:
3235:
3232:
3230:
3227:
3225:
3222:
3220:
3217:
3215:
3212:
3210:
3209:Protoanemonin
3207:
3205:
3202:
3200:
3197:
3195:
3194:Oenanthotoxin
3192:
3190:
3187:
3185:
3182:
3180:
3177:
3175:
3172:
3170:
3167:
3165:
3162:
3160:
3157:
3155:
3152:
3150:
3147:
3145:
3142:
3140:
3137:
3135:
3132:
3130:
3127:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3107:
3105:
3102:
3101:
3099:
3096:
3092:
3086:
3083:
3081:
3078:
3076:
3073:
3071:
3070:Trichothecene
3068:
3066:
3063:
3061:
3058:
3056:
3053:
3051:
3048:
3046:
3043:
3041:
3038:
3036:
3033:
3031:
3030:Ibotenic acid
3028:
3026:
3023:
3020:
3016:
3012:
3008:
3005:
3003:
3000:
2998:
2995:
2993:
2990:
2988:
2985:
2982:
2978:
2974:
2973:beta-amanitin
2970:
2966:
2963:
2961:
2958:
2957:
2955:
2953:
2949:
2939:
2936:
2934:
2931:
2930:
2928:
2926:
2920:
2912:
2909:
2907:
2904:
2903:
2901:
2897:
2893:
2890:
2888:
2885:
2884:
2883:
2881:
2877:
2873:
2870:
2869:
2868:
2865:
2864:
2862:
2860:
2856:
2844:
2840:
2837:
2836:
2835:
2834:
2830:
2826:
2823:
2822:
2821:
2820:
2816:
2812:
2809:
2808:
2807:
2806:
2802:
2801:
2799:
2797:
2793:
2787:
2784:
2782:
2779:
2777:
2774:
2772:
2768:
2767:Cholera toxin
2765:
2763:
2761:
2757:
2754:
2751:
2750:
2748:
2746:
2740:
2730:
2727:
2725:
2722:
2721:
2719:
2717:
2713:
2703:
2700:
2698:
2695:
2693:
2690:
2688:
2684:
2680:
2677:
2676:
2674:
2671:
2666:
2658:
2655:
2654:
2653:
2650:
2648:
2645:
2644:
2641:
2638:
2636:
2632:
2622:
2619:
2617:
2616:Anthrax toxin
2614:
2613:
2611:
2605:
2597:
2594:
2593:
2592:
2591:
2587:
2583:
2580:
2578:
2575:
2574:
2573:
2572:
2568:
2564:
2561:
2559:
2556:
2555:
2554:
2553:
2549:
2545:
2542:
2540:
2539:Tetanospasmin
2537:
2536:
2535:
2534:
2530:
2529:
2527:
2523:
2518:
2515:
2513:
2509:
2506:
2504:
2498:
2495:
2493:
2489:
2486:
2484:
2478:
2470:
2467:
2465:
2462:
2460:
2457:
2455:
2452:
2450:
2447:
2445:
2442:
2440:
2437:
2436:
2435:
2432:
2431:
2426:
2421:
2419:
2414:
2412:
2407:
2406:
2403:
2391:
2388:
2386:
2383:
2381:
2378:
2376:
2373:
2371:
2368:
2367:
2365:
2361:
2355:
2352:
2350:
2347:
2345:
2342:
2340:
2337:
2335:
2332:
2331:
2329:
2325:
2319:
2316:
2314:
2311:
2309:
2306:
2305:
2303:
2301:
2297:
2291:
2288:
2286:
2283:
2281:
2278:
2276:
2273:
2271:
2268:
2266:
2263:
2261:
2258:
2256:
2253:
2251:
2248:
2246:
2243:
2241:
2238:
2236:
2233:
2231:
2228:
2226:
2223:
2221:
2218:
2216:
2213:
2211:
2208:
2206:
2203:
2201:
2198:
2196:
2193:
2192:
2190:
2188:
2184:
2178:
2175:
2173:
2170:
2168:
2165:
2163:
2160:
2158:
2155:
2153:
2150:
2148:
2145:
2143:
2140:
2138:
2137:Methamidophos
2135:
2133:
2130:
2128:
2125:
2123:
2120:
2118:
2117:Fenpropathrin
2115:
2114:
2112:
2110:
2106:
2100:
2097:
2095:
2092:
2090:
2089:Ibotenic acid
2087:
2086:
2084:
2082:
2078:
2072:
2069:
2067:
2064:
2062:
2059:
2057:
2056:Oenanthotoxin
2054:
2052:
2049:
2047:
2044:
2042:
2039:
2037:
2034:
2032:
2029:
2027:
2024:
2022:
2019:
2017:
2014:
2012:
2009:
2008:
2006:
2004:
2000:
1994:
1991:
1989:
1986:
1984:
1981:
1979:
1976:
1975:
1973:
1971:
1967:
1961:
1960:Tetanospasmin
1958:
1956:
1953:
1952:
1950:
1948:
1944:
1938:
1935:
1933:
1930:
1928:
1925:
1923:
1920:
1918:
1915:
1913:
1910:
1908:
1905:
1903:
1900:
1898:
1895:
1893:
1890:
1888:
1885:
1883:
1882:Charybdotoxin
1880:
1878:
1875:
1873:
1870:
1868:
1865:
1863:
1862:Batrachotoxin
1860:
1859:
1857:
1855:Animal toxins
1853:
1849:
1842:
1837:
1835:
1830:
1828:
1823:
1822:
1819:
1808:
1804:
1800:
1796:
1792:
1788:
1785:(3): 305–10.
1784:
1780:
1773:
1770:
1765:
1761:
1757:
1753:
1749:
1745:
1741:
1737:
1729:
1726:
1721:
1717:
1713:
1709:
1704:
1699:
1695:
1691:
1687:
1680:
1677:
1672:
1668:
1664:
1660:
1656:
1652:
1648:
1644:
1639:
1634:
1630:
1626:
1622:
1618:
1611:
1608:
1603:
1599:
1595:
1593:1-59259-816-1
1589:
1585:
1581:
1577:
1566:
1563:
1558:
1554:
1549:
1544:
1540:
1536:
1532:
1525:
1522:
1517:
1513:
1508:
1503:
1499:
1495:
1491:
1484:
1481:
1476:
1472:
1468:
1464:
1460:
1456:
1453:(2): 329–37.
1452:
1448:
1441:
1438:
1433:
1429:
1425:
1421:
1417:
1413:
1410:(2): 517–26.
1409:
1405:
1398:
1395:
1390:
1386:
1381:
1376:
1372:
1368:
1365:(2): 447–55.
1364:
1360:
1356:
1349:
1346:
1341:
1337:
1333:
1329:
1326:(3): 419–30.
1325:
1321:
1314:
1311:
1306:
1302:
1297:
1292:
1288:
1284:
1280:
1276:
1272:
1265:
1263:
1259:
1254:
1250:
1246:
1242:
1238:
1234:
1233:Life Sciences
1227:
1224:
1213:
1209:
1203:
1201:
1197:
1192:
1188:
1183:
1178:
1174:
1170:
1166:
1162:
1155:
1152:
1147:
1143:
1139:
1135:
1131:
1127:
1120:
1117:
1112:
1108:
1103:
1098:
1095:(2): 367–71.
1094:
1090:
1086:
1079:
1076:
1071:
1067:
1063:
1059:
1055:
1051:
1044:
1041:
1036:
1030:
1026:
1015:
1012:
1007:
1003:
999:
995:
990:
985:
981:
977:
973:
966:
964:
962:
958:
953:
949:
945:
941:
938:(8): 1560–2.
937:
933:
926:
924:
922:
918:
913:
909:
905:
901:
897:
893:
889:
885:
882:(3): 228–38.
881:
877:
870:
867:
862:
858:
854:
850:
845:
840:
836:
832:
828:
821:
818:
815:
813:
806:
803:
798:
794:
789:
784:
779:
774:
770:
766:
762:
755:
752:
747:
743:
738:
733:
730:(2): 457–69.
729:
725:
721:
714:
712:
710:
708:
706:
702:
695:
693:
691:
690:
685:
682:) venom, and
681:
680:
675:
671:
670:
665:
661:
655:
653:
651:
646:
638:
636:
613:
597:
595:
592:
590:
589:catecholamine
586:
580:
574:
570:
561:
559:
557:
553:
545:
543:
541:
538:activity and
537:
536:anticoagulant
533:
529:
501:
488:
486:
482:
478:
474:
470:
466:
461:
458:
450:
448:
442:
434:
419:
417:
415:
407:
403:
399:
394:
392:
384:
377:
374:
370:
366:
362:
358:
346:
343:
339:
336:
333:
329:
324:
320:
317:
314:
312:
308:
304:
300:
296:
292:
288:
283:
278:
267:
264:
260:
257:
254:
250:
245:
241:
238:
235:
233:
229:
226:
223:
221:
217:
213:
209:
205:
201:
197:
192:
187:
176:
173:
169:
166:
163:
159:
154:
150:
147:
144:
142:
138:
135:
132:
130:
126:
122:
118:
114:
110:
106:
101:
96:
85:
82:
78:
75:
72:
68:
63:
59:
56:
53:
51:
47:
43:
39:
35:
31:
27:
22:
17:
3785:Snake toxins
3740:
3719:Calcicludine
3709:Calciseptine
3692:Bungarotoxin
3661:Tarichatoxin
3609:Arenobufagin
3573:Tetrodotoxin
3532:Tetrodotoxin
3486:Vanillotoxin
3423:Phaiodotoxin
3326:Invertebrate
3249:Solasodamine
3184:Lotaustralin
3019:Fumonisin B4
3015:Fumonisin B2
3011:Fumonisin B1
2997:Cytochalasin
2899:
2879:
2831:
2817:
2811:Superantigen
2803:
2759:
2647:Streptolysin
2588:
2569:
2550:
2531:
2187:Nerve agents
2003:Plant toxins
1917:Vanillotoxin
1912:Tetrodotoxin
1877:Bungarotoxin
1782:
1778:
1772:
1739:
1735:
1728:
1693:
1690:FEBS Letters
1689:
1679:
1620:
1616:
1610:
1575:
1565:
1538:
1534:
1524:
1497:
1493:
1483:
1450:
1446:
1440:
1407:
1403:
1397:
1362:
1358:
1348:
1323:
1319:
1313:
1281:(1): 61–75.
1278:
1274:
1236:
1232:
1226:
1215:. Retrieved
1211:
1164:
1160:
1154:
1129:
1125:
1119:
1092:
1089:FEBS Letters
1088:
1078:
1053:
1049:
1043:
1020:
1014:
979:
975:
935:
931:
879:
875:
869:
834:
830:
820:
811:
805:
768:
764:
754:
727:
723:
687:
684:textilotoxin
677:
667:
662:
659:
642:
601:
593:
581:
565:
549:
528:cytotoxicity
489:
462:
454:
423:
395:
375:
359:is a potent
356:
355:
3780:Neurotoxins
3682:Snake venom
3636:Epibatidine
3624:Cinobufagin
3481:Stromatoxin
3428:Imperatoxin
3378:Scyllatoxin
3284:Tagetitoxin
3279:Swainsonine
3269:Solauricine
3234:Solamargine
3229:Scopolamine
3219:Retronecine
3085:Zearalenone
2753:Shiga toxin
2724:Cord factor
2563:Enterotoxin
2558:Alpha toxin
2552:perfringens
2544:Tetanolysin
2522:Clostridium
2459:hepatotoxin
2449:enterotoxin
2439:cardiotoxin
2339:Catecholine
2280:Fluorotabun
2127:Bromethalin
2071:Veratridine
2046:Ginkgotoxin
2016:Bicuculline
1970:Cyanotoxins
1937:Dendrotoxin
1927:Epibatidine
1902:Poneratoxin
1848:Neurotoxins
1742:(1): 6–11.
1574:Activity".
1182:10669/29394
771:(10): 302.
540:hypotensive
506:enzymes/PLA
335:Swiss-model
285:Identifiers
256:Swiss-model
194:Identifiers
165:Swiss-model
103:Identifiers
74:Swiss-model
24:Identifiers
3774:Categories
3714:Taicatoxin
3651:Samandarin
3604:Bufotoxins
3568:Ciguatoxin
3546:Vertebrate
3491:Huwentoxin
3471:Cupiennins
3454:Latrotoxin
3398:Kaliotoxin
3368:Margatoxin
3358:Maurotoxin
3299:Toxalbumin
3289:Tinyatoxin
3274:Strychnine
3259:Solasonine
3254:Solasodine
3239:Solanidine
3159:Falcarinol
3144:Delphinine
3060:Phalloidin
3050:Ochratoxin
3045:Orellanine
3035:Lolitrem B
3002:Ergotamine
2952:Mycotoxins
2796:Mechanisms
2755:/Verotoxin
2692:Exfoliatin
2652:Leukocidin
2469:phototoxin
2464:neurotoxin
2285:Chinese VX
2195:Cyclosarin
2142:Endosulfan
2109:Pesticides
2081:Mycotoxins
2031:Strychnine
2026:Picrotoxin
2021:Penitrem A
1983:Guanitoxin
1978:Anatoxin-a
1897:Huwentoxin
1892:Fasciculin
1217:2017-03-17
696:References
365:neurotoxin
331:Structures
326:Search for
252:Structures
247:Search for
161:Structures
156:Search for
70:Structures
65:Search for
3619:Bufotenin
3614:Bufotalin
3584:Amphibian
3527:Saxitoxin
3517:Eledoisin
3512:Conotoxin
3383:Hefutoxin
3199:Oleandrin
3179:Linamarin
3169:Helenalin
3129:Cicutoxin
3124:Chaconine
3104:Amygdalin
3075:Vomitoxin
3025:Gliotoxin
3007:Fumonisin
2960:Aflatoxin
2923:Virulence
2859:Endotoxin
2590:botulinum
2571:difficile
2481:Bacterial
2454:hemotoxin
2444:cytotoxin
2132:Crimidine
2094:Muscarine
2066:Volkensin
2051:Cicutoxin
2011:Aconitine
1993:Saxitoxin
1947:Bacterial
1907:Saxitoxin
1887:Conotoxin
1633:CiteSeerX
645:antivenom
639:Treatment
542:effects.
451:Structure
3759:Category
3522:Onchidal
3502:Mollusca
3413:Bestoxin
3408:Birtoxin
3373:Slotoxin
3363:Agitoxin
3338:Scorpion
3294:Tomatine
3244:Solanine
3189:Mimosine
3164:Gossypol
3149:Divicine
3114:Antiarin
3109:Anisatin
3040:Muscimol
2992:Citrinin
2965:Amatoxin
2911:Cry34Ab1
2839:AB toxin
2833:type III
2745:negative
2503:positive
2492:Exotoxin
2172:Schradan
2147:Fipronil
2099:Muscimol
2041:Rotenone
1872:Birtoxin
1867:Bestoxin
1807:16083544
1799:24129771
1756:17293048
1720:38178998
1712:17083939
1671:39970648
1663:16339444
1602:15173620
1516:10748068
1467:12675909
1424:10686073
1389:10027403
952:18471843
861:22678139
853:16805767
812:Taipoxin
797:27763543
616:Taipoxin
598:Toxicity
569:myotoxic
518:, as PLA
391:asphyxia
357:Taipoxin
345:InterPro
290:Organism
266:InterPro
199:Organism
175:InterPro
108:Organism
84:InterPro
29:Organism
3677:Reptile
3139:Daphnin
3134:Coniine
3119:Brucine
3080:Zeranol
3055:Patulin
2902:toxins
2892:Cry3Bb1
2872:Lipid A
2819:type II
2760:E. coli
2512:Bacilli
2290:EA-2192
2265:EA-4056
2260:EA-3990
2200:EA-3148
2177:Dimefox
2167:Mipafox
2061:Thujone
1764:7635663
1655:3842969
1625:Bibcode
1617:Science
1557:9261167
1475:8907229
1432:6714210
1380:1850016
1340:7245222
1320:Toxicon
1305:7082907
1296:2068749
1253:7300571
1191:8744981
1161:Toxicon
1146:7886694
1126:Toxicon
1070:8866614
1050:Toxicon
1025:Enzymes
1006:2136068
998:9914497
932:Toxicon
912:6203372
904:2120459
884:Bibcode
788:5086662
692:venom.
672:venom,
664:Notexin
420:History
371:of the
341:Domains
311:UniProt
262:Domains
232:UniProt
171:Domains
141:UniProt
80:Domains
50:UniProt
3549:toxins
3444:Spider
3418:BmKAEP
3388:HgeTx1
3329:toxins
3204:Persin
3097:toxins
2925:factor
2906:Cry6Aa
2898:Other
2887:Cry1Ac
2805:type I
2608:Other:
2533:tetani
2483:toxins
2434:Toxins
2270:T-1123
1805:
1797:
1762:
1754:
1718:
1710:
1669:
1661:
1653:
1635:
1600:
1590:
1555:
1514:
1473:
1465:
1430:
1422:
1387:
1377:
1338:
1303:
1293:
1251:
1189:
1144:
1111:563806
1109:
1068:
1031:
1004:
996:
950:
910:
902:
859:
851:
795:
785:
765:Toxins
746:976268
744:
573:oedema
441:enzyme
402:Dalton
363:- and
316:P00616
302:Symbol
237:P0CG57
211:Symbol
146:P00615
120:Symbol
55:P00614
41:Symbol
3476:PhTx3
3393:HsTx1
3316:Tutin
3309:Ricin
3304:Abrin
3174:Ledol
3095:Plant
2687:delta
2635:Cocci
2596:Botox
2363:Other
2318:IPTBO
2220:Tabun
2215:Soman
2210:Sarin
2036:Tutin
1803:S2CID
1760:S2CID
1716:S2CID
1667:S2CID
1651:JSTOR
1471:S2CID
1428:S2CID
1002:S2CID
908:S2CID
857:S2CID
814:(pdf)
473:pH(I)
369:venom
3558:Fish
3466:CSTX
2743:Gram
2683:beta
2501:Gram
2385:IDPN
2313:TBPO
2308:TBPS
1988:BMAA
1795:PMID
1752:PMID
1708:PMID
1659:PMID
1598:PMID
1588:ISBN
1553:PMID
1512:PMID
1463:PMID
1420:PMID
1385:PMID
1336:PMID
1301:PMID
1249:PMID
1187:PMID
1142:PMID
1107:PMID
1066:PMID
1029:ISBN
994:PMID
948:PMID
900:PMID
849:PMID
793:PMID
742:PMID
514:/PLA
396:The
385:(PLA
225:3vbz
134:3VC0
3433:Pi3
3403:Lq2
2843:AB5
1787:doi
1744:doi
1740:416
1698:doi
1694:580
1643:doi
1621:310
1580:doi
1543:doi
1539:272
1502:doi
1498:275
1455:doi
1412:doi
1408:161
1375:PMC
1367:doi
1363:154
1328:doi
1291:PMC
1283:doi
1241:doi
1177:hdl
1169:doi
1134:doi
1097:doi
1058:doi
984:doi
980:259
940:doi
892:doi
839:doi
783:PMC
773:doi
732:doi
626:+ K
622:+ K
618:= K
554:by
483:or
430:PLA
416:).
408:(LD
361:myo
220:PDB
129:PDB
3776::
3013:,
2979:,
2975:,
2971:,
2255:GV
2250:VX
2245:VR
2240:VP
2235:VM
2230:VG
2225:VE
1801:.
1793:.
1783:25
1781:.
1758:.
1750:.
1738:.
1714:.
1706:.
1692:.
1688:.
1665:.
1657:.
1649:.
1641:.
1631:.
1619:.
1596:.
1586:.
1551:.
1537:.
1533:.
1510:.
1496:.
1492:.
1469:.
1461:.
1451:85
1449:.
1426:.
1418:.
1406:.
1383:.
1373:.
1361:.
1357:.
1334:.
1324:19
1322:.
1299:.
1289:.
1279:76
1277:.
1273:.
1261:^
1247:.
1237:29
1235:.
1210:.
1199:^
1185:.
1175:.
1165:33
1163:.
1140:.
1130:32
1128:.
1105:.
1093:84
1091:.
1087:.
1064:.
1054:33
1052:.
1000:.
992:.
978:.
974:.
960:^
946:.
936:51
934:.
920:^
906:.
898:.
890:.
880:31
878:.
855:.
847:.
835:97
833:.
829:.
791:.
781:.
767:.
763:.
740:.
728:68
726:.
722:.
704:^
534:,
410:50
3684::
3679:/
3586::
3560::
3504::
3446::
3340::
3021:)
3009:(
2983:)
2967:(
2841:/
2769:/
2685:/
2681:/
2582:B
2577:A
2524::
2424:e
2417:t
2410:v
1840:e
1833:t
1826:v
1809:.
1789::
1766:.
1746::
1722:.
1700::
1673:.
1645::
1627::
1604:.
1582::
1572:2
1559:.
1545::
1518:.
1504::
1477:.
1457::
1434:.
1414::
1391:.
1369::
1342:.
1330::
1307:.
1285::
1255:.
1243::
1220:.
1193:.
1179::
1171::
1148:.
1136::
1113:.
1099::
1072:.
1060::
1037:.
1023:2
1008:.
986::
954:.
942::
914:.
894::
886::
863:.
841::
799:.
775::
769:8
748:.
734::
632:2
628:C
624:B
620:A
608:2
604:2
577:2
524:2
520:2
516:2
512:2
508:2
504:2
496:2
492:2
445:2
437:2
432:2
426:2
387:2
382:2
305:?
214:?
123:?
44:?
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.