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28 Nov 2009 removed a tag from chembox that was messing up the display of the page. The tag contained: | InChI = 1/C23H38N7O17P3S/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38)/t13-,16-,17-,18+,22-/m1/s1 I have no idea what this means or how to fix it, but someone may want to.
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313:) states that the "heart gets little energy from ketone bodies; it uses mainly fatty acids." This is contrary to the current article's "both the skeletal and cardiac muscles satisfy their energy requirement mainly through oxidation of ketone bodies." I don't know which one is right (did look in PubMed and found some articles suggesting limited ketone body usage by skeletal muscle). Clarify.
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compound, other searches may find for many compounds many mismatches, e.g. the name can be written in different ways, the formula can be sorted in a different way, but some of these codes are always leading to the right compound). It is hidden behind a 'show' button so it does not mess up the page in normal view, but is still there so it
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Hello everyone, I have been reading up on Acetyl-CoA and come across various papers that I think would be helpful to our Acetyl-CoA article. As such, I hope to make some edits to the current page so that anyone who is interested can know more about it. Here is an outline of the improvement I hope to
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It is not good form to leave invisible text in the current versions of the article. I found a block of text, surrounded by the
Knowledge (XXG) comment markers, so that it did not show. Some editor "removed" it my "commenting it out". The correct editing technique it to actually delete it, and let
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The InChI is a code that identifies the compound. It is for the untrained person unreadable (and this one probably also for trained people), but it can be machine read. Having this code on the page results that you can find this compound using internet search engines (i.e., for sure find THIS
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Thanks for the tips! I picked melatonin since it was the only section that didn't have any description and there's been really interesting developments in research regarding the relationship between melatonin synthesis and Acetyl-CoA. I also wanted to ask if you knew why journal articles were
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other editors use the saved previous versions to restore it or do what ever they want with the removed text. For instance you can see what I removed by looking at the version immediately before my change, using my name and time appended here.
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4.I also hope to reorganize some of the ideas into the relevant subsections such that the introduction of Acetyl CoA only covers the basic details of what it is, its overall structure and a brief mention of its role in metabolism pathways.
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As a new editor to
Knowledge (XXG), you are to be congratulated for getting this far and for requesting feedback. Here it is: 1) keep the information general, 2) cite general sources (textbooks, monographs, major reviews),
490:-CoA" emphasizes the central importance of the acetyl group, a fact that is further emphasized in the introduction to the article. I therefore think it is only fair to the general reader that the appropriate diagram here is
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I don't know, but chemspider says that the IUPAC name is: S-methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphor​ yl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl​] ethanethioate.
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a.Fatty acid production (move the available information in the current article to here) b.Mevalonate pathway (MVA) - isoprenoids an sterols production c.Ketone bodies production
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I would really appreciate any feedback/suggestion on the outline and if there is anything I can do to further improve the depth and quality of our current article. Thank you!:)
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be read. It may mess up the display in show-mode, but that is easily repaired by clicking hide again, or refreshing the page. I hope this explains. --
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494:. I wonder whether you would consider using the colored version of the diagram here - it would save a lot of unnecessary bafflement.
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779:. Do not include words in the art. Words go into captions. Acetyl-CoA is involved in many processes, so why pick melatonin? --
523:, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.
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This article is or was the subject of a Wiki
Education Foundation-supported course assignment. Further details are available
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molecule (except to those who have a very extensive grounding in organic chemistry and its many and varied symbolisms).
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1.Move the Direct
Synthesis out of Function and put it as a stand-alone section. I plan to add these categories to it:
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with one showing the acetyl group in blue. You improved on this diagram, creating <Acetyl-CoA-2D_colored.svg: -->
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Ethanol coversion to acetaldehyde (by alcohol dehydrogenase), then to acetate and eventually to acetyl coA.
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ATP-citrate lysase catalysed conversion of citrate from cytoplasm to oxaloacetate and acetyl CoA in cytosol
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Thank you so much for your advice! I truly appreciate it and would keep it in mind as I make my edits :)
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three of the nitrogens are missing hydrogens (the two amides and the amino group on the aromatic ring).
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on
Knowledge (XXG). If you would like to participate, please visit the project page, where you can join
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468:, I replaced the introductory diagram of the structure of acetyl-CoA <File:Acetyl-CoA-2D.svg: -->
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This article was the subject of a Wiki
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740:- Insert images for synthesis pathways for the examples mentioned in the “Functions” section
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article. However, you reverted the one here with the original <File:Acetyl-CoA-2D.svg: -->
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Hello. I wanted to make additional edits on this article. Here are my proposed edits below:
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Last edited at 20:43, 18 February 2007 (UTC). Substituted at 06:35, 29 April 2016 (UTC)
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Edit the bullet points into paragraphs for the “Functions” section and add information
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a. Role in mitosis and cell growth through histone acetylation b. Role in apoptosis
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Degradation of ketogenic branched-chain amino acids (valine, leucine, and isoleucine)
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Add more pictures to the “Functions” section and “Extramitochondrial” subsection
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Oxidative decarboxylation of pyruvate through pyruvate dehydrogenase complex
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Feel free to let me know your opinions and if you have any feedback ˙ᵕ˙
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14:47, 18 February 2007 (UTC) This article has no references/sources. -
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rated High as high school/SAT biology topic, part of cell metabolism -
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which does not make it clear which part of the molecule is the
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Find more recent sources for “Intramitochondrial” synthesis
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3.Add a small section on
History of Acetyl CoA discovery.
99:. To participate, help improve this article or visit the
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discouraged from being sources in the discussion above?
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only reviews or books, no primary literature, please.
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731:- Expand on Acetyl-CoA’s role in melatonin synthesis
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Wiki
Education Foundation-supported course assignment
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WikiProject
Molecular and Cellular Biology articles
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
