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His research is centered on the application of various computer science and mathematical methods for the discovery of the syntactic and semantic patterns in nucleic acid and amino acid sequences. In recent years this has focus on molecular evolution of protein families. such as the WD-repeat beta
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Venkatesan, Kavitha, McManus, Heather R., Mello, Craig C., Smith, Temple F. and Hansen, Ulla. (2003). Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead. Nucleic Acids
Research 31(15),
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Bienkowska, Jadwiga, Hartman, Hyman and Smith, Temple F. (2003). A search method for homologs of small proteins, Ubiquitin-like proteins in prokaryotic cells? Protein
Engineering 16 (12), 897–904.
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Bhutkar, Arjun V., Gelbart, William M. and Smith, Temple F. (2007). Inferring genome-scale rearrangement phylogeny and ancestral gene order: A Drosophila case study. Genome
Biology 8, R236
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M. Mariotti, T. F. Smith, P. H. Sudmant and G. Goldberger, “Pseudogenization of testis-specific Lfg5 predates human/Neanderthal divergence”, Journal of Human
Genetics 59, 288–291 (2014)
392:“for extraordinary contributions in defining and advancing the field of bioinformatics, with emphasis on novel engineering methods to predict protein structure and function”.
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Zhang YX1, Fox JG, Ho Y, Zhang L, Stills HF Jr, Smith TF. Comparison of the major outer-membrane protein (MOMP) gene of mouse pneumonitis (MoPn) and hamster SFPD strains of
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Bhutkar, Arjun, Russo, Susan M., Smith, Temple F. and
Gelbart, William M. “Genome-Scale Analysis of Positionally Relocated Genes” Genome Research 17: 1880-1887 (2007)
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in 1981. The Smith-Waterman algorithm serves as the basis for multi sequence comparisons, identifying the segment with the maximum local sequence similarity, see
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Smith, Temple F., Lee, Jung C., Gutell, Robin R. and
Hartman, Hyman. “The Origin and Evolution of the Ribosome” Biology Direct 3: 16, 1–13 (2008)
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Hartman, Hyman and Smith, Temple F. “The evolution of the cilium and the eukaryotic cell” Cell
Motility and the Cytoskeleton.66: 215-219. (2009)
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284:, Molecular Biology Computer Research Resource, Dana-Farber Cancer Institute, Harvard Medical School and the Harvard School of Public Health
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Hartman, Hyman, Favaretto, Paola and Smith, Temple F. “The
Archaeal Origins of the Eukaryotic Translational System” Archaea 2: 1-9 (2006)
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Hu, Lan, Smith, Temple F. and
Goldberger, Gabriel. “LFG: a candidate apoptosis regulatory gene family” Apoptosis. 14: 1255-1265. (2009)
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Figge J, Smith TF. Cell division sequence motif. Nature 334 (6178), 109 (14 July 1988) |pmid=3290690 |doi=10.1038/334109a0.
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from March 1969 to August 1971 in the
Department of Biophysics and Genetics, University of Colorado Medical School, Boulder.
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Hyman Hartman and Temple F. Smith “The Evolution of the Ribosome and the Genetic Code”, Life, 4(2), 227–249 (2014)
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propellers, translation associated GTPase, and the ribosomal proteins. He is known for the creation of the
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Smith, Temple F. “Chapter 2: Diversity of WD-Repeat Proteins” The Coronin Family of Proteins, 20–30 (2008)
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Hartman, H and T. F. Smith, “GTPases and the origin of the ribosome”, Biology Direct, 5:36-39, (2010)
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298:, 1999 Institute for the Academic Advancement of Youth Discovering Biotechnology Day
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segments. He was director of the BioMolecular Engineering Research Center at
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The deuteron amplitudes from a composite particle nuclear scattering theory
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The deuteron amplitudes from a composite particle nuclear scattering theory
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Smith obtained his bachelor's degree in 1963 from the Physics Department,
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Fellows of the American Institute for Medical and Biological Engineering
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with other Chlamydia strains. Mol Biol Evol. 1993 Nov;10(6):1327–42.
277:, Department of Physics, Northern Michigan University, Marquette, MI
562:"BioMolecular Engineering Research Center | Boston University"
390:
American Institute for Medical and Biological Engineering (AIMBE)
666:
1440:
Fellows of the International Society for Computational Biology
291:, BioMolecular Engineering Resource Center, Boston University
208:
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511:(1981). "Identification of common molecular subsequences".
642:"Temple F. Smith, Ph.D. » Microbiology » BUMC"
235:, followed by a PhD in 1969 in the Physics Department,
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614:(PhD thesis). University of Colorado at Boulder.
203:. This algorithm is used for identifying similar
187:(born March 7, 1939) is an emeritus professor in
698:International Society for Computational Biology
485:International Society for Computational Biology
383:International Society for Computational Biology
678:
8:
414:"ISCB Honors Temple F. Smith and Eran Segal"
262:Smith has held the following appointments:
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303:Co-Founder and Chief Information Officer
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219:for twenty years and is now professor
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270:, US Air Force Lowery, Denver, CO
237:University of Colorado at Boulder
308:2000– : Youth Hockey Coach
388:Im 2002, he was inducted into
77:University of Colorado Boulder
1:
610:Smith, Temple Ferris (1969).
537:10.1016/0022-2836(81)90087-5
514:Journal of Molecular Biology
441:10.1371/journal.pcbi.0030128
35:Temple Smith at Yale in 2008
375:ISCB Senior Scientist Award
104:ISCB Senior Scientist Award
1466:
1435:American bioinformaticians
419:PLOS Computational Biology
191:who helped to develop the
247:After his PhD, Smith did
154:
119:
28:
305:, Modular Genetics, Inc.
257:Smith-Waterman algorithm
193:Smith-Waterman algorithm
91:Smith-Waterman algorithm
487:. 2017. Archived from
373:Smith was awarded the
189:biomedical engineering
358:Chlamydia trachomatis
313:Selected publications
249:postdoctoral research
174:/temple-f-smith-ph-d
1343:Gustavo Stolovitzky
967:Julio Collado-Vides
432:2007PLSCB...3..128M
412:Maisel, M. (2007).
243:Research and career
185:Temple Ferris Smith
45:Temple Ferris Smith
1409:Reinhard Schneider
1201:Marie-France Sagot
1196:Xiaole Shirley Liu
201:sequence alignment
1417:
1416:
1323:NĂşria LĂłpez Bigas
1257:Katherine Pollard
1217:Serafim Batzoglou
1140:Terry Gaasterland
864:Gunnar von Heijne
803:Michael Ashburner
369:Awards and honors
233:Purdue University
217:Boston University
182:
181:
131:Boston University
121:Scientific career
72:Purdue University
16:American academic
1457:
1374:Takashi Gojobori
1333:Teresa Przytycka
1313:Christina Leslie
1135:Patricia Babbitt
1114:Olga Troyanskaya
1038:Christine Orengo
936:Robert Gentleman
787:Alfonso Valencia
746:Michael Waterman
702:year of election
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644:. Archived from
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59:Auburn, New York
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1247:Rafael Irizarry
1227:Mark Borodovsky
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1160:William Pearson
1123:
1089:Andrea Califano
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1058:Anna Tramontano
1053:Sarah Teichmann
1008:Helen M. Berman
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982:Thomas Lengauer
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890:Minoru Kanehisa
885:David Eisenberg
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381:in 2009 by the
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586:"Temple Smith"
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528:10.1.1.63.2897
521:(1): 195–197.
494:
491:on 2017-03-20.
477:"ISCB Fellows"
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48:March 7, 1939
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20:
1399:Debora Marks
1338:Eytan Ruppin
1267:Zhiping Weng
1252:Laxmi Parida
1232:Rita Casadio
1222:Judith Blake
1186:Vineet Bafna
1119:Tandy Warnow
1109:Lior Pachter
1099:Anders Krogh
1084:Alex Bateman
1068:Haim Wolfson
1018:Dan Gusfield
931:Nir Friedman
921:Amos Bairoch
880:Pierre Baldi
844:Jill Mesirov
813:Søren Brunak
777:Chris Sander
772:Eugene Myers
736:Temple Smith
735:
721:David Lipman
650:. Retrieved
646:the original
636:
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594:. Retrieved
590:the original
580:
569:. Retrieved
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489:the original
480:
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377:and elected
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296:Co-organizer
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127:Institutions
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23:Temple Smith
1445:1939 births
1384:David Jones
1379:Trey Ideker
1262:Ben Raphael
1242:Osamu Gotoh
1237:Paul Flicek
1150:Yves Moreau
1028:Janet Kelso
1023:Barry Honig
977:Des Higgins
941:Andrej Ĺ ali
926:Ewan Birney
808:Phil Bourne
782:Gary Stormo
762:Russ Altman
726:Webb Miller
507:Smith, T.;
426:(6): e128.
379:ISCB Fellow
287:1991–2009:
280:1985–1991:
273:1971–1984:
266:1965–1966:
110:ISCB Fellow
1424:Categories
1328:Dana Pe'er
1288:Atul Butte
1170:Mike Steel
1165:Mona Singh
1043:Aviv Regev
854:Ron Shamir
839:Peter Karp
652:2011-10-28
596:2007-05-03
571:2017-03-24
396:References
353:4304–4316.
268:Instructor
52:1939-03-07
1404:Mihai Pop
1364:Sean Eddy
628:302393082
523:CiteSeerX
275:Professor
227:Education
624:ProQuest
620:50252533
481:iscb.org
460:17604447
289:Director
282:Director
221:emeritus
172:/profile
1394:Jun Liu
1318:Ming Li
696:of the
694:Fellows
545:7265238
451:1904388
428:Bibcode
213:protein
159:Website
50: (
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149:(1969)
147:
138:Thesis
112:(2009)
106:(2007)
97:Awards
195:with
79:(PhD)
1352:2022
1281:2021
1210:2020
1179:2019
1128:2018
1077:2017
1001:2016
950:2015
914:2014
873:2013
827:2012
796:2011
755:2010
709:2009
616:OCLC
541:PMID
456:PMID
211:and
170:/eng
168:.edu
41:Born
700:by
533:doi
519:147
446:PMC
436:doi
209:RNA
205:DNA
166:.bu
164:www
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