325:
302:
27:
199:
224:
583:
576:
1109:
1183:
presence of these antibodies can result in falsely low (or rarely falsely high) levels of reported thyroglobulin, a problem that can be somewhat circumvented by concomitant testing for the presence of ATAs. The ideal strategy for a clinician's interpretation and management of patient care in the event of confounding detection of ATAs is testing to follow serial quantitative measurements (rather than a single laboratory measurement).
590:
331:
230:
1162:
A subsequent elevation of the thyroglobulin level is an indication of recurrence of papillary or follicular thyroid carcinoma. In other words, a rise in thyroglobulin levels in the blood may be a sign that thyroid cancer cells are growing and/or the cancer is spreading. Hence, thyroglobulin levels in
1068:
and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in the extracellular compartment of the thyroid follicles, accounting for approximately half of the protein content of the thyroid gland. Human TG (hTG) is a homodimer of subunits each containing
1182:
In the clinical laboratory, thyroglobulin testing can be complicated by the presence of anti-thyroglobulin antibodies (ATAs, alternatively referred to as TgAb). Anti-thyroglobulin antibodies are present in 1 in 10 normal individuals, and a greater percentage of patients with thyroid carcinoma. The
1158:
Metabolism of thyroglobulin occurs in the liver via thyroid gland recycling of the protein. Circulating thyroglobulin has a half-life of 65 hours. Following thyroidectomy, it may take many weeks before thyroglobulin levels become undetectable. Thyroglobulin levels may be tested regularly for a few
1144:
The active forms of thyroid hormone: T3 and T4, are then released into circulation where they are either unbound or attached to plasma proteins, and thyroglobulin is recycled back into the follicular lumen where it can continue to serve as a substrate for thyroid hormone synthesis.
1159:
weeks or months following the removal of the thyroid. After thyroglobulin levels become undetectable (following thyroidectomy), levels can be serially monitored in follow-up of patients with papillary or follicular thyroid carcinoma.
1141:(TSH), the colloid is endocytosed from the follicular lumen into the surrounding thyroid follicular epithelial cells. The colloid is subsequently cleaved by proteases to release thyroglobulin from its T3 and T4 attachments.
1967:
Kubak BM, Potempa LA, Anderson B, Mahklouf S, Venegas M, Gewurz H, Gewurz AT (September 1988). "Evidence that serum amyloid P component binds to mannose-terminated sequences of polysaccharides and glycoproteins".
1559:
Delom F, Lejeune PJ, Vinet L, Carayon P, Mallet B (February 1999). "Involvement of oxidative reactions and extracellular protein chaperones in the rescue of misassembled thyroglobulin in the follicular lumen".
2135:
Avvedimento VE, Di Lauro R, Monticelli A, Bernardi F, Patracchini P, Calzolari E, et al. (1985). "Mapping of human thyroglobulin gene on the long arm of chromosome 8 by in situ hybridization".
4372:
1520:"Role of extracellular molecular chaperones in the folding of oxidized proteins. Refolding of colloidal thyroglobulin by protein disulfide isomerase and immunoglobulin heavy chain-binding protein"
1475:
Ferracci F, Moretto G, Candeago RM, Cimini N, Conte F, Gentile M, et al. (February 2003). "Antithyroid antibodies in the CSF: their role in the pathogenesis of
Hashimoto's encephalopathy".
1686:
Henry M, Zanelli E, Piechaczyk M, Pau B, Malthièry Y (February 1992). "A major human thyroglobulin epitope defined with monoclonal antibodies is mainly recognized by human autoantibodies".
2034:
Parma J, Christophe D, Pohl V, Vassart G (August 1987). "Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution".
2063:
Bergé-Lefranc JL, Cartouzou G, Mattéi MG, Passage E, Malezet-Desmoulins C, Lissitzky S (1985). "Localization of the thyroglobulin gene by in situ hybridization to human chromosomes".
1092:
and the protein is subsequently cleaved. Each thyroglobulin molecule contains approximately 16 tyrosine residues, but only a small number 10 of these are subject to iodination by
2308:
Yang SX, Pollock HG, Rawitch AB (March 1996). "Glycosylation in human thyroglobulin: location of the N-linked oligosaccharide units and comparison with bovine thyroglobulin".
2240:"Preferential sites of proteolytic cleavage of bovine, human and rat thyroglobulin. The use of limited proteolysis to detect solvent-exposed regions of the primary structure"
2201:
Corral J, MartĂn C, PĂ©rez R, Sánchez I, Mories MT, San Millan JL, et al. (February 1993). "Thyroglobulin gene point mutation associated with non-endemic simple goitre".
2936:
4365:
56:
338:
237:
2172:
Xiao S, Pollock HG, Taurog A, Rawitch AB (June 1995). "Characterization of hormonogenic sites in an N-terminal, cyanogen bromide fragment of human thyroglobulin".
4358:
2468:
783:
764:
160:
1723:
Targovnik HM, Cochaux P, Corach D, Vassart G (March 1992). "Identification of a minor Tg mRNA transcript in RNA from normal and goitrous thyroids".
1100:. It takes two iodinated tyrosines to make a thyroid hormone molecule; therefore, each Tg molecule forms approximately 5 thyroid hormone molecules.
3527:
2970:
1450:
1997:
Malthiéry Y, Lissitzky S (June 1987). "Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA".
1137:
Newly synthesized thyroid hormones (T3 and T4) are attached to thyroglobulin and comprise the colloid within the follicle. When stimulated by
1295:
1277:
4856:
324:
3347:
983:
3719:
1653:"A consensus report of the role of serum thyroglobulin as a monitoring method for low-risk patients with papillary thyroid carcinoma"
990:
301:
4861:
3387:
1325:
1171:(particularly papillary or follicular thyroid cancer). Thyroglobulin is not produced by medullary or anaplastic thyroid carcinoma.
1134:(T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle.
78:
3966:
3905:
3237:
4145:
3737:
2461:
1264:
1243:
4041:
2915:
2102:"Sequence of the 5'-end quarter of the human-thyroglobulin messenger ribonucleic acid and of its deduced amino-acid sequence"
1215:
2339:"Characterization of the type-1 repeat from thyroglobulin, a cysteine-rich module found in proteins from different families"
1260:
223:
198:
4135:
3805:
2374:"Thyroglobulin in lymph node fine-needle aspiration washout: a systematic review and meta-analysis of diagnostic accuracy"
1199:
1239:
4834:
4088:
4019:
3991:
3764:
2646:
140:
39:
3520:
3484:
2963:
2414:
1211:
1138:
1116:
49:
43:
35:
2275:"N-glycans modulate in vivo and in vitro thyroid hormone synthesis. Study at the N-terminal domain of thyroglobulin"
4588:
4474:
4130:
3474:
2454:
1187:
92:
337:
236:
4125:
3437:
3397:
2910:
2435:
1832:"Hormone synthesis in human thyroglobulin: possible cleavage of the polypeptide chain at the tyrosine donor site"
1194:. Their presence is of limited use in the diagnosis of these diseases, since they may also be present in healthy
1174:
Thyroglobulin levels are tested via a simple blood test. Tests are often ordered after thyroid cancer treatment.
1112:
1883:"An unusually long poly(purine)-poly(pyrimidine) sequence is located upstream from the human thyroglobulin gene"
60:
4741:
4570:
4409:
4381:
3920:
3895:
3867:
3795:
3625:
3616:
3377:
3352:
2521:
828:
330:
229:
148:
2804:
2429:
4605:
4392:
2581:
1061:
809:
2948:
2419:
4876:
4866:
4565:
4188:
3999:
3513:
3412:
2956:
4632:
4398:
4033:
3900:
2607:
1454:
1651:
Mazzaferri EL, Robbins RJ, Spencer CA, Braverman LE, Pacini F, Wartofsky L, et al. (April 2003).
4642:
4623:
3659:
2864:
2680:
2425:
1843:
1613:
212:
127:
1762:"Thyroglobulin processing by thyroidal proteases. Major sites of cleavage by cathepsins B, D, and L"
4594:
3980:
3417:
3342:
3229:
3206:
3170:
3142:
2859:
2799:
2545:
2535:
2525:
4680:
4384:
3367:
2885:
2777:
2226:
2160:
2088:
2022:
1869:
1748:
1711:
1500:
172:
1191:
966:
945:
919:
898:
4509:
1600:
Coscia F, Taler-Verčič A, Chang VT, Sinn L, O'Reilly FJ, Izoré T, et al. (February 2020).
4519:
4514:
4093:
4080:
4005:
3928:
3882:
3854:
3690:
3442:
3271:
2894:
2794:
2737:
2395:
2360:
2325:
2296:
2261:
2218:
2189:
2152:
2123:
2080:
2051:
2014:
1985:
1955:
1912:
1861:
1818:
1783:
1740:
1703:
1674:
1639:
1577:
1541:
1492:
1395:
1321:
1054:
120:
4534:
4504:
4871:
4777:
4721:
4716:
4696:
4669:
4499:
4469:
4327:
3636:
3577:
3357:
3174:
3127:
2477:
2440:
2385:
2350:
2317:
2286:
2251:
2210:
2181:
2144:
2113:
2072:
2043:
2006:
1977:
1945:
1937:
1902:
1894:
1851:
1808:
1773:
1732:
1695:
1664:
1629:
1621:
1569:
1531:
1484:
1131:
582:
575:
417:
348:
292:
247:
4560:
4439:
4434:
1108:
4544:
4429:
4180:
4117:
4055:
4013:
3820:
3644:
3314:
3286:
3202:
2636:
2557:
1124:
1093:
1081:
589:
392:
1847:
1617:
168:
4767:
4757:
4198:
3957:
3672:
3603:
3464:
2983:
2752:
2709:
2626:
2531:
2517:
2497:
2256:
2239:
2118:
2101:
2010:
1634:
1601:
1488:
1168:
1070:
4350:
1950:
1926:"The human thyroglobulin gene is over 300 kb long and contains introns of up to 64 kb"
1925:
1907:
1882:
1813:
1796:
1778:
1761:
698:
693:
688:
683:
678:
673:
668:
652:
647:
631:
4850:
4762:
4638:
4444:
4221:
3682:
3667:
3569:
3457:
3137:
2869:
2851:
2747:
2743:
2575:
2355:
2338:
2214:
2047:
1981:
1856:
1831:
1736:
618:
96:
2230:
2164:
2026:
1873:
1797:"Consensus sequences for early iodination and hormonogenesis in human thyroglobulin"
1752:
1715:
1504:
4726:
4484:
4449:
4047:
4027:
3759:
3747:
3536:
3382:
3294:
3161:
2991:
2987:
2541:
2485:
2092:
1426:
1341:
1164:
1057:
410:
189:
1202:, a neuroendocrine disorder related to—but not caused by—Hashimoto's thyroiditis.
152:
176:
4772:
4711:
4701:
4648:
4628:
4306:
4244:
3833:
3824:
3787:
3729:
3711:
3494:
3489:
3479:
3452:
3422:
3407:
3276:
3132:
3122:
2999:
2900:
2890:
2782:
2733:
2670:
2651:
2611:
2600:
2568:
2273:
Mallet B, Lejeune PJ, Baudry N, Niccoli P, Carayon P, Franc JL (December 1995).
1346:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1300:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1282:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1881:
Christophe D, Cabrer B, Bacolla A, Targovnik H, Pohl V, Vassart G (July 1985).
1387:
493:
4802:
4529:
4524:
4494:
4464:
4297:
3620:
3559:
3322:
2831:
1625:
1074:
309:
206:
156:
2291:
2274:
1941:
1898:
4706:
4459:
4293:
3800:
3649:
3432:
3427:
3402:
3392:
3304:
2836:
2823:
2695:
2675:
1195:
1127:
728:
553:
431:
376:
363:
275:
262:
164:
2399:
2321:
2185:
1699:
1678:
1669:
1652:
1643:
1581:
1573:
1545:
1536:
1519:
1496:
1399:
2364:
2329:
2300:
2265:
2222:
2193:
2156:
2127:
2084:
2055:
2018:
1989:
1959:
1916:
1865:
1822:
1787:
1744:
1707:
1030:
1025:
4817:
4807:
4731:
4283:
4249:
4234:
3751:
3551:
3251:
3246:
3241:
3219:
3214:
3192:
3187:
3147:
2717:
2685:
2488:
2390:
2373:
1359:
1085:
1014:
873:
854:
4539:
4454:
4275:
4229:
4165:
4061:
3299:
3182:
2979:
2814:
2757:
2690:
2148:
2076:
1924:
Baas F, van Ommen GJ, Bikker H, Arnberg AC, de
Vijlder JJ (July 1986).
1097:
1065:
840:
795:
4797:
4663:
4335:
4150:
4097:
3972:
3932:
3890:
3862:
3372:
3091:
3051:
2841:
2507:
1089:
998:
750:
2446:
4254:
4239:
4211:
4206:
4170:
4155:
4140:
4107:
4069:
3910:
3872:
3810:
3582:
3266:
3261:
3106:
3101:
3096:
3086:
3081:
3076:
3056:
3041:
3036:
3021:
3008:
2905:
1107:
713:
709:
4160:
4102:
3986:
3505:
3447:
3362:
3256:
3071:
3066:
3061:
3046:
3031:
3026:
3016:
1123:
Thyroglobulin (Tg) acts as a substrate for the synthesis of the
144:
4354:
3509:
2952:
2450:
1360:"TG thyroglobulin [Homo sapiens (human)] – Gene – NCBI"
598:
1050:
20:
1115:, this image traces thyroglobulin from production within the
1080:
Thyroglobulin is in all vertebrates the main precursor to
1390:. In Feingold KR, Anawalt B, Boyce A, Chrousos G (eds.).
1342:"Protein" thyroglobulin precursor [Homo sapiens]"
400:
1830:
Marriq C, Lejeune PJ, Venot N, Vinet L (January 1989).
2443: – Histology Learning System at Boston University
2337:
Molina F, Bouanani M, Pau B, Granier C (August 1996).
1518:
Delom F, Mallet B, Carayon P, Lejeune PJ (June 2001).
1795:
Lamas L, Anderson PC, Fox JW, Dunn JT (August 1989).
1318:
Medical
Physiology: A Cellular And Molecular Approach
565:
2378:
The
Journal of Clinical Endocrinology and Metabolism
1657:
The
Journal of Clinical Endocrinology and Metabolism
1364:
4790:
4740:
4679:
4662:
4604:
4587:
4553:
4483:
4422:
4408:
4391:
4326:
4319:
4292:
4274:
4267:
4220:
4197:
4179:
4116:
4079:
3956:
3945:
3919:
3881:
3853:
3846:
3819:
3786:
3777:
3746:
3728:
3710:
3703:
3681:
3658:
3635:
3602:
3595:
3568:
3550:
3543:
3335:
3313:
3285:
3228:
3201:
3169:
3160:
3115:
3007:
2998:
2878:
2850:
2822:
2813:
2770:
2726:
2708:
2661:
2634:
2625:
2590:
2555:
2505:
2496:
2484:
1562:
1388:"Chapter 2 Thyroid Hormone Synthesis and Secretion"
959:
938:
912:
891:
1256:
1254:
1252:
1235:
1233:
1231:
1198:individuals. ATAs are also found in patients with
1119:until proteolytic release of the thyroid hormones.
1760:Dunn AD, Crutchfield HE, Dunn JT (October 1991).
1427:"Thyroglobulin: MedlinePlus Lab Test Information"
347:
246:
4742:
4410:
48:but its sources remain unclear because it lacks
4606:
1386:Rousset BL, Dupuy C, Miot F, Dumont J (2000).
1381:
1379:
1261:GRCm38: Ensembl release 89: ENSMUSG00000053469
4366:
3521:
2964:
2462:
8:
1240:GRCh38: Ensembl release 89: ENSG00000042832
4681:
4676:
4601:
4419:
4405:
4373:
4359:
4351:
4323:
4271:
3953:
3850:
3783:
3707:
3599:
3547:
3528:
3514:
3506:
3166:
3004:
2971:
2957:
2949:
2819:
2631:
2502:
2493:
2469:
2455:
2447:
2100:Malthiéry Y, Lissitzky S (February 1985).
1084:, which are produced when thyroglobulin's
1073:of 19 amino acids may be removed from the
724:
614:
388:
287:
184:
2937:disorders of globin and globulin proteins
2389:
2354:
2290:
2255:
2117:
1949:
1906:
1855:
1812:
1777:
1668:
1633:
1535:
1453:. American Cancer Society. Archived from
1069:2768 amino acids as synthesized (a short
699:regulation of signaling receptor activity
79:Learn how and when to remove this message
2238:Gentile F, Salvatore G (December 1993).
18:Protein produced and used by the thyroid
3277:Structural maintenance of chromosomes 3
2415:First look at the structure of human TG
2310:Archives of Biochemistry and Biophysics
2174:Archives of Biochemistry and Biophysics
1311:
1309:
1227:
1602:"The structure of human thyroglobulin"
1186:ATAs are often found in patients with
101:
352:
313:
308:
251:
210:
205:
7:
1725:Molecular and Cellular Endocrinology
1421:
1419:
1417:
1415:
2279:The Journal of Biological Chemistry
1801:The Journal of Biological Chemistry
1766:The Journal of Biological Chemistry
1524:The Journal of Biological Chemistry
1320:. Elsevier/Saunders. p. 1044.
4571:Tetraiodothyroacetic acid (Tetrac)
2257:10.1111/j.1432-1033.1993.tb18414.x
2119:10.1111/j.1432-1033.1985.tb08717.x
2011:10.1111/j.1432-1033.1987.tb11466.x
1489:10.1212/01.wnl.0000048660.71390.c6
956:
935:
909:
888:
864:
845:
819:
800:
774:
755:
570:
488:
426:
405:
14:
3388:Cholesterylester transfer protein
3238:Chondroitin sulfate proteoglycans
2372:Grani G, Fumarola A (June 2014).
669:thyroid hormone metabolic process
4768:Ipodate sodium (sodium iopodate)
4747:Tooltip Iodothyronine deiodinase
4415:Tooltip Thyroid hormone receptor
3967:Surface epithelial-stromal tumor
3906:Tumor-associated glycoprotein 72
2356:10.1111/j.1432-1033.1996.0125h.x
2343:European Journal of Biochemistry
2244:European Journal of Biochemistry
2106:European Journal of Biochemistry
1999:European Journal of Biochemistry
1210:Thyroglobulin has been shown to
1154:Half-life and clinical elevation
588:
581:
574:
336:
329:
323:
300:
235:
228:
222:
197:
25:
4611:Tooltip Sodium-iodide symporter
4146:Early prostate cancer antigen-2
3738:Glial fibrillary acidic protein
1163:the blood are mainly used as a
2916:Extracellular matrix protein 1
1688:European Journal of Immunology
1216:Binding immunoglobulin protein
599:More reference expression data
554:More reference expression data
1:
4835:Receptor/signaling modulators
4136:Glutamate carboxypeptidase II
1814:10.1016/S0021-9258(18)80031-X
1779:10.1016/S0021-9258(18)54909-7
321:
220:
3765:Melanoma inhibitory activity
2647:Sex hormone-binding globulin
2215:10.1016/0140-6736(93)90209-Y
2048:10.1016/0022-2836(87)90403-7
2036:Journal of Molecular Biology
1982:10.1016/0161-5890(88)90121-6
1857:10.1016/0014-5793(89)80513-7
1737:10.1016/0303-7207(92)90087-M
694:hormone biosynthetic process
4857:Genes on human chromosome 8
3485:Tumor necrosis factor alpha
1451:"ACS :: Tumor Markers"
1139:thyroid stimulating hormone
1117:rough endoplasmic reticulum
1088:residues are combined with
446:right lobe of thyroid gland
131:, AITD3, TGN, thyroglobulin
4893:
4686:Tooltip Thyroid peroxidase
4530:Sobetirome (GC-1, GRX-431)
4131:Prostatic acid phosphatase
4042:Sertoli–Leydig cell tumour
3475:Thyroxine-binding proteins
1200:Hashimoto's encephalopathy
442:left lobe of thyroid gland
93:thyroxine-binding globulin
90:
4826:
4126:Prostate-specific antigen
3806:Autocrine motility factor
3438:Serum amyloid P component
3398:Colony-stimulating factor
2928:
2911:Vitamin D-binding protein
2441:Histology image: 14302loa
2436:Overview at colostate.edu
1626:10.1038/s41586-020-1995-4
1296:"Mouse PubMed Reference:"
1278:"Human PubMed Reference:"
1113:Thyroid hormone synthesis
1029:
1024:
1020:
1013:
997:
984:Chr 8: 132.87 – 133.13 Mb
978:
963:
942:
931:
916:
895:
884:
871:
867:
852:
848:
839:
826:
822:
807:
803:
794:
781:
777:
762:
758:
749:
734:
727:
723:
707:
679:regulation of myelination
674:thyroid gland development
617:
613:
596:
573:
564:
551:
500:
491:
438:
429:
399:
391:
387:
370:
357:
320:
299:
290:
286:
269:
256:
219:
196:
187:
183:
138:
135:
125:
118:
113:
109:
104:
4862:Diagnostic endocrinology
4382:Thyroid hormone receptor
3921:Hepatocellular carcinoma
3896:Carcinoembryonic antigen
3868:Carcinoembryonic antigen
3796:Carcinoembryonic antigen
3626:Carcinoembryonic antigen
3617:Medullary thyroid cancer
3378:B-cell activating factor
3353:Alpha 1-antichymotrypsin
2522:Alpha 1-antichymotrypsin
2292:10.1074/jbc.270.50.29881
1178:Thyroglobulin antibodies
1077:in the mature protein).
991:Chr 15: 66.54 – 66.72 Mb
91:Not to be confused with
34:This article includes a
2805:7S seed storage protein
2582:Retinol binding protein
1188:Hashimoto's thyroiditis
63:more precise citations.
3413:Membrane glycoproteins
2322:10.1006/abbi.1996.0093
2186:10.1006/abbi.1995.1346
1942:10.1093/nar/14.13.5171
1930:Nucleic Acids Research
1899:10.1093/nar/13.14.5127
1887:Nucleic Acids Research
1700:10.1002/eji.1830220205
1670:10.1210/jc.2002-021702
1574:10.1006/bbrc.1999.0229
1537:10.1074/jbc.M101086200
1120:
4633:potassium perchlorate
4624:Cyanogenic glycosides
3660:Neuroendocrine tumors
2608:alpha-2-Macroglobulin
1167:for certain kinds of
1149:Clinical significance
1111:
512:lobe of thyroid gland
354:15 D2|15 29.3 cM
315:Chromosome 15 (mouse)
4643:sodium pertechnetate
4495:Eprotirome (KB-2115)
4488:(selective agonists)
2865:Bovine serum albumin
2681:Beta-2 microglobulin
2391:10.1210/jc.2014-1098
1970:Molecular Immunology
648:extracellular region
462:right adrenal cortex
213:Chromosome 8 (human)
3418:Myelin protein zero
3343:Activin and inhibin
3143:Phytohaemagglutinin
2860:Human serum albumin
2800:11S globulin family
2546:Heparin cofactor II
2536:Alpha 2-antiplasmin
2526:Alpha 1-antitrypsin
2285:(50): 29881–29888.
1848:1989FEBSL.242..414M
1807:(23): 13541–13545.
1772:(30): 20198–20204.
1618:2020Natur.578..627C
1530:(24): 21337–21342.
1394:. MDText.com, Inc.
689:signal transduction
653:extracellular space
536:endocardial cushion
474:right lobe of liver
4465:Tiratricol (TRIAC)
3368:Asialoglycoprotein
2886:C-reactive protein
2778:Beta-lactoglobulin
2422:– Lab Tests Online
2149:10.1007/BF00283375
2077:10.1007/BF00295525
1121:
1096:in the follicular
829:ENSMUSG00000053469
662:Biological process
641:Cellular component
625:Molecular function
36:list of references
4844:
4843:
4786:
4785:
4673:
4658:
4657:
4598:
4583:
4582:
4579:
4578:
4402:
4348:
4347:
4344:
4343:
4315:
4314:
4268:General histology
4263:
4262:
4094:Alpha-fetoprotein
4081:Testicular cancer
4006:Alpha-fetoprotein
3941:
3940:
3929:Alpha-fetoprotein
3883:Pancreatic cancer
3855:Colorectal cancer
3842:
3841:
3773:
3772:
3699:
3698:
3691:Homovanillic acid
3591:
3590:
3503:
3502:
3443:Sialoglycoprotein
3331:
3330:
3272:Platelet factor 4
3156:
3155:
2946:
2945:
2924:
2923:
2895:Alpha-lactalbumin
2795:Alpha-lactalbumin
2766:
2765:
2738:Fetal fibronectin
2704:
2703:
2621:
2620:
2478:Globular proteins
2426:Histology at KUMC
2209:(8843): 462–464.
1936:(13): 5171–5186.
1893:(14): 5127–5144.
1612:(7796): 627–630.
1316:Boron WF (2003).
1040:
1039:
1036:
1035:
1009:
1008:
974:
973:
953:
952:
927:
926:
906:
905:
880:
879:
861:
860:
835:
834:
816:
815:
790:
789:
771:
770:
719:
718:
609:
608:
605:
604:
560:
559:
547:
546:
485:
484:
383:
382:
282:
281:
89:
88:
81:
4884:
4778:Propylthiouracil
4748:
4744:
4722:Propylthiouracil
4717:Methylthiouracil
4697:Benzylthiouracil
4687:
4683:
4677:
4667:
4612:
4608:
4602:
4592:
4470:Triiodothyronine
4420:
4416:
4412:
4406:
4396:
4375:
4368:
4361:
4352:
4328:Rhabdomyosarcoma
4324:
4272:
3954:
3851:
3784:
3708:
3637:Pheochromocytoma
3600:
3548:
3530:
3523:
3516:
3507:
3358:Apolipoprotein H
3167:
3128:Intrinsic factor
3005:
2973:
2966:
2959:
2950:
2820:
2664:
2640:
2637:carrier proteins
2632:
2593:
2561:
2558:carrier proteins
2511:
2503:
2494:
2471:
2464:
2457:
2448:
2403:
2393:
2384:(6): 1970–1982.
2368:
2358:
2333:
2304:
2294:
2269:
2259:
2234:
2197:
2168:
2131:
2121:
2096:
2059:
2030:
1993:
1963:
1953:
1920:
1910:
1877:
1859:
1826:
1816:
1791:
1781:
1756:
1731:(1–2): R23–R26.
1719:
1682:
1672:
1663:(4): 1433–1441.
1647:
1637:
1586:
1585:
1556:
1550:
1549:
1539:
1515:
1509:
1508:
1472:
1466:
1465:
1463:
1462:
1447:
1441:
1440:
1438:
1437:
1423:
1410:
1409:
1407:
1406:
1383:
1374:
1373:
1371:
1370:
1356:
1350:
1349:
1338:
1332:
1331:
1313:
1304:
1303:
1292:
1286:
1285:
1274:
1268:
1258:
1247:
1237:
1132:triiodothyronine
1125:thyroid hormones
1082:thyroid hormones
1062:follicular cells
1060:produced by the
1022:
1021:
993:
986:
969:
957:
948:
936:
932:RefSeq (protein)
922:
910:
901:
889:
865:
846:
820:
801:
775:
756:
725:
684:iodide transport
632:hormone activity
615:
601:
592:
585:
578:
571:
556:
496:
494:Top expressed in
489:
434:
432:Top expressed in
427:
406:
389:
379:
366:
355:
340:
333:
327:
316:
304:
288:
278:
265:
254:
239:
232:
226:
215:
201:
185:
179:
130:
123:
102:
84:
77:
73:
70:
64:
59:this article by
50:inline citations
29:
28:
21:
4892:
4891:
4887:
4886:
4885:
4883:
4882:
4881:
4847:
4846:
4845:
4840:
4822:
4782:
4746:
4736:
4685:
4666:
4654:
4651:
4613:
4610:
4591:
4575:
4549:
4487:
4479:
4475:Thyroid extract
4430:Dextrothyroxine
4414:
4395:
4387:
4379:
4349:
4340:
4320:Musculoskeletal
4311:
4288:
4259:
4240:erbB-3 receptor
4235:erbB-2 receptor
4216:
4207:erbB-3 receptor
4193:
4181:Germ cell tumor
4175:
4141:erbB-3 receptor
4118:Prostate cancer
4112:
4075:
4014:Choriocarcinoma
3949:
3947:
3937:
3915:
3877:
3838:
3821:Hemangiosarcoma
3815:
3779:
3778:Cardiovascular/
3769:
3742:
3724:
3695:
3677:
3654:
3645:Normetanephrine
3631:
3587:
3564:
3539:
3534:
3504:
3499:
3327:
3309:
3281:
3224:
3197:
3152:
3111:
2994:
2977:
2947:
2942:
2941:
2920:
2874:
2846:
2809:
2771:Other globulins
2762:
2722:
2718:Immunoglobulins
2700:
2662:
2657:
2654:
2635:
2617:
2591:
2586:
2556:
2551:
2506:
2498:Alpha globulins
2480:
2475:
2411:
2406:
2371:
2336:
2307:
2272:
2237:
2200:
2171:
2134:
2099:
2062:
2033:
1996:
1966:
1923:
1880:
1829:
1794:
1759:
1722:
1685:
1650:
1599:
1595:
1593:Further reading
1590:
1589:
1558:
1557:
1553:
1517:
1516:
1512:
1474:
1473:
1469:
1460:
1458:
1449:
1448:
1444:
1435:
1433:
1431:medlineplus.gov
1425:
1424:
1413:
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1315:
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1307:
1294:
1293:
1289:
1276:
1275:
1271:
1259:
1250:
1238:
1229:
1224:
1208:
1192:Graves' disease
1180:
1156:
1151:
1106:
1094:thyroperoxidase
1031:View/Edit Mouse
1026:View/Edit Human
989:
982:
979:Location (UCSC)
965:
944:
918:
897:
810:ENSG00000042832
703:
657:
636:
597:
587:
586:
580:
579:
552:
543:
538:
534:
530:
526:
522:
518:
514:
510:
506:
492:
481:
476:
472:
468:
464:
460:
458:skin of abdomen
456:
452:
448:
444:
430:
374:
361:
353:
343:
342:
341:
334:
314:
291:Gene location (
273:
260:
252:
242:
241:
240:
233:
211:
188:Gene location (
139:
126:
119:
100:
85:
74:
68:
65:
54:
40:related reading
30:
26:
19:
12:
11:
5:
4890:
4888:
4880:
4879:
4874:
4869:
4864:
4859:
4849:
4848:
4842:
4841:
4839:
4838:
4827:
4824:
4823:
4821:
4820:
4815:
4810:
4805:
4800:
4794:
4792:
4788:
4787:
4784:
4783:
4781:
4780:
4775:
4770:
4765:
4760:
4758:Dexpropranolol
4751:
4749:
4738:
4737:
4735:
4734:
4729:
4724:
4719:
4714:
4709:
4704:
4699:
4690:
4688:
4674:
4660:
4659:
4656:
4655:
4653:
4652:
4646:
4639:Pertechnetates
4636:
4626:
4617:
4615:
4599:
4585:
4584:
4581:
4580:
4577:
4576:
4574:
4573:
4568:
4563:
4557:
4555:
4551:
4550:
4548:
4547:
4542:
4537:
4532:
4527:
4522:
4517:
4512:
4507:
4502:
4497:
4491:
4489:
4481:
4480:
4478:
4477:
4472:
4467:
4462:
4457:
4452:
4447:
4442:
4437:
4432:
4426:
4424:
4417:
4403:
4389:
4388:
4380:
4378:
4377:
4370:
4363:
4355:
4346:
4345:
4342:
4341:
4339:
4338:
4332:
4330:
4321:
4317:
4316:
4313:
4312:
4310:
4309:
4303:
4301:
4290:
4289:
4287:
4286:
4280:
4278:
4269:
4265:
4264:
4261:
4260:
4258:
4257:
4252:
4247:
4242:
4237:
4232:
4226:
4224:
4218:
4217:
4215:
4214:
4209:
4203:
4201:
4199:Bladder cancer
4195:
4194:
4192:
4191:
4185:
4183:
4177:
4176:
4174:
4173:
4168:
4163:
4158:
4153:
4148:
4143:
4138:
4133:
4128:
4122:
4120:
4114:
4113:
4111:
4110:
4105:
4100:
4091:
4085:
4083:
4077:
4076:
4074:
4073:
4066:
4065:
4064:
4052:
4051:
4050:
4038:
4037:
4036:
4024:
4023:
4022:
4010:
4009:
4008:
3996:
3995:
3994:
3989:
3977:
3976:
3975:
3962:
3960:
3951:
3943:
3942:
3939:
3938:
3936:
3935:
3925:
3923:
3917:
3916:
3914:
3913:
3908:
3903:
3898:
3893:
3887:
3885:
3879:
3878:
3876:
3875:
3870:
3865:
3859:
3857:
3848:
3844:
3843:
3840:
3839:
3837:
3836:
3830:
3828:
3817:
3816:
3814:
3813:
3808:
3803:
3798:
3792:
3790:
3781:
3775:
3774:
3771:
3770:
3768:
3767:
3762:
3756:
3754:
3744:
3743:
3741:
3740:
3734:
3732:
3726:
3725:
3723:
3722:
3716:
3714:
3705:
3704:Nervous system
3701:
3700:
3697:
3696:
3694:
3693:
3687:
3685:
3679:
3678:
3676:
3675:
3673:Chromogranin A
3670:
3664:
3662:
3656:
3655:
3653:
3652:
3647:
3641:
3639:
3633:
3632:
3630:
3629:
3623:
3614:
3608:
3606:
3604:Thyroid cancer
3597:
3593:
3592:
3589:
3588:
3586:
3585:
3580:
3574:
3572:
3566:
3565:
3563:
3562:
3556:
3554:
3545:
3541:
3540:
3535:
3533:
3532:
3525:
3518:
3510:
3501:
3500:
3498:
3497:
3492:
3487:
3482:
3477:
3472:
3467:
3465:Thrombopoietin
3462:
3461:
3460:
3455:
3450:
3440:
3435:
3430:
3425:
3420:
3415:
3410:
3405:
3400:
3395:
3390:
3385:
3380:
3375:
3370:
3365:
3360:
3355:
3350:
3345:
3339:
3337:
3333:
3332:
3329:
3328:
3326:
3325:
3319:
3317:
3311:
3310:
3308:
3307:
3302:
3297:
3291:
3289:
3283:
3282:
3280:
3279:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3234:
3232:
3226:
3225:
3223:
3222:
3217:
3211:
3209:
3199:
3198:
3196:
3195:
3190:
3185:
3179:
3177:
3164:
3158:
3157:
3154:
3153:
3151:
3150:
3145:
3140:
3135:
3130:
3125:
3119:
3117:
3113:
3112:
3110:
3109:
3104:
3099:
3094:
3089:
3084:
3079:
3074:
3069:
3064:
3059:
3054:
3049:
3044:
3039:
3034:
3029:
3024:
3019:
3013:
3011:
3002:
2996:
2995:
2984:glycoconjugate
2978:
2976:
2975:
2968:
2961:
2953:
2944:
2943:
2940:
2939:
2930:
2929:
2926:
2925:
2922:
2921:
2919:
2918:
2913:
2908:
2903:
2898:
2888:
2882:
2880:
2876:
2875:
2873:
2872:
2867:
2862:
2856:
2854:
2848:
2847:
2845:
2844:
2839:
2834:
2828:
2826:
2817:
2811:
2810:
2808:
2807:
2802:
2797:
2792:
2787:
2786:
2785:
2774:
2772:
2768:
2767:
2764:
2763:
2761:
2760:
2755:
2753:Transcobalamin
2750:
2741:
2730:
2728:
2724:
2723:
2721:
2720:
2714:
2712:
2710:Gamma globulin
2706:
2705:
2702:
2701:
2699:
2698:
2693:
2688:
2683:
2678:
2673:
2667:
2665:
2659:
2658:
2656:
2655:
2649:
2643:
2641:
2629:
2627:Beta globulins
2623:
2622:
2619:
2618:
2616:
2615:
2604:
2596:
2594:
2588:
2587:
2585:
2584:
2579:
2572:
2564:
2562:
2553:
2552:
2550:
2549:
2539:
2529:
2514:
2512:
2500:
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2482:
2481:
2476:
2474:
2473:
2466:
2459:
2451:
2445:
2444:
2438:
2433:
2423:
2417:
2410:
2409:External links
2407:
2405:
2404:
2369:
2349:(1): 125–133.
2334:
2305:
2270:
2250:(2): 603–621.
2235:
2198:
2169:
2143:(2): 163–166.
2137:Human Genetics
2132:
2097:
2065:Human Genetics
2060:
2042:(4): 769–779.
2031:
2005:(3): 491–498.
1994:
1976:(9): 851–858.
1964:
1921:
1878:
1842:(2): 414–418.
1827:
1792:
1757:
1720:
1694:(2): 315–319.
1683:
1648:
1596:
1594:
1591:
1588:
1587:
1568:(2): 438–443.
1551:
1510:
1483:(4): 712–714.
1467:
1442:
1411:
1375:
1351:
1333:
1326:
1305:
1287:
1269:
1248:
1226:
1225:
1223:
1220:
1207:
1204:
1179:
1176:
1169:thyroid cancer
1155:
1152:
1150:
1147:
1105:
1102:
1071:signal peptide
1038:
1037:
1034:
1033:
1028:
1018:
1017:
1011:
1010:
1007:
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1002:
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516:tail of embryo
513:
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480:
479:
478:left ventricle
475:
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443:
439:
436:
435:
423:
422:
414:
403:
397:
396:
393:RNA expression
385:
384:
381:
380:
372:
368:
367:
359:
356:
351:
345:
344:
335:
328:
322:
318:
317:
312:
306:
305:
297:
296:
284:
283:
280:
279:
271:
267:
266:
258:
255:
250:
244:
243:
234:
227:
221:
217:
216:
209:
203:
202:
194:
193:
181:
180:
177:TG - orthologs
137:
133:
132:
124:
116:
115:
111:
110:
107:
106:
87:
86:
44:external links
33:
31:
24:
17:
13:
10:
9:
6:
4:
3:
2:
4889:
4878:
4877:Tumor markers
4875:
4873:
4870:
4868:
4867:Endocrinology
4865:
4863:
4860:
4858:
4855:
4854:
4852:
4837:
4836:
4833:
4829:
4828:
4825:
4819:
4816:
4814:
4813:Thyroglobulin
4811:
4809:
4806:
4804:
4801:
4799:
4796:
4795:
4793:
4789:
4779:
4776:
4774:
4771:
4769:
4766:
4764:
4763:Iopanoic acid
4761:
4759:
4756:
4753:
4752:
4750:
4745:
4739:
4733:
4730:
4728:
4725:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4695:
4692:
4691:
4689:
4684:
4678:
4675:
4671:
4665:
4661:
4650:
4647:
4644:
4640:
4637:
4634:
4630:
4627:
4625:
4622:
4619:
4618:
4616:
4609:
4603:
4600:
4596:
4590:
4586:
4572:
4569:
4567:
4564:
4562:
4559:
4558:
4556:
4552:
4546:
4543:
4541:
4538:
4536:
4533:
4531:
4528:
4526:
4523:
4521:
4518:
4516:
4513:
4511:
4508:
4506:
4503:
4501:
4498:
4496:
4493:
4492:
4490:
4486:
4485:Thyromimetics
4482:
4476:
4473:
4471:
4468:
4466:
4463:
4461:
4458:
4456:
4453:
4451:
4448:
4446:
4445:Levothyroxine
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4427:
4425:
4421:
4418:
4413:
4407:
4404:
4400:
4394:
4390:
4386:
4383:
4376:
4371:
4369:
4364:
4362:
4357:
4356:
4353:
4337:
4334:
4333:
4331:
4329:
4325:
4322:
4318:
4308:
4305:
4304:
4302:
4299:
4295:
4291:
4285:
4282:
4281:
4279:
4277:
4273:
4270:
4266:
4256:
4253:
4251:
4248:
4246:
4243:
4241:
4238:
4236:
4233:
4231:
4228:
4227:
4225:
4223:
4222:Breast cancer
4219:
4213:
4210:
4208:
4205:
4204:
4202:
4200:
4196:
4190:
4187:
4186:
4184:
4182:
4178:
4172:
4169:
4167:
4164:
4162:
4159:
4157:
4154:
4152:
4149:
4147:
4144:
4142:
4139:
4137:
4134:
4132:
4129:
4127:
4124:
4123:
4121:
4119:
4115:
4109:
4106:
4104:
4101:
4099:
4095:
4092:
4090:
4087:
4086:
4084:
4082:
4078:
4072:
4071:
4067:
4063:
4060:
4059:
4058:
4057:
4053:
4049:
4046:
4045:
4044:
4043:
4039:
4035:
4032:
4031:
4030:
4029:
4025:
4021:
4018:
4017:
4016:
4015:
4011:
4007:
4004:
4003:
4002:
4001:
3997:
3993:
3990:
3988:
3985:
3984:
3983:
3982:
3978:
3974:
3971:
3970:
3969:
3968:
3964:
3963:
3961:
3959:
3958:Ovarian tumor
3955:
3952:
3946:Reproductive/
3944:
3934:
3930:
3927:
3926:
3924:
3922:
3918:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3892:
3889:
3888:
3886:
3884:
3880:
3874:
3871:
3869:
3866:
3864:
3861:
3860:
3858:
3856:
3852:
3849:
3845:
3835:
3832:
3831:
3829:
3826:
3822:
3818:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3793:
3791:
3789:
3785:
3782:
3776:
3766:
3763:
3761:
3758:
3757:
3755:
3753:
3749:
3745:
3739:
3736:
3735:
3733:
3731:
3727:
3721:
3718:
3717:
3715:
3713:
3709:
3706:
3702:
3692:
3689:
3688:
3686:
3684:
3683:Neuroblastoma
3680:
3674:
3671:
3669:
3668:Synaptophysin
3666:
3665:
3663:
3661:
3657:
3651:
3648:
3646:
3643:
3642:
3640:
3638:
3634:
3627:
3624:
3622:
3618:
3615:
3613:
3612:Thyroglobulin
3610:
3609:
3607:
3605:
3601:
3598:
3594:
3584:
3581:
3579:
3576:
3575:
3573:
3571:
3570:Lymphosarcoma
3567:
3561:
3558:
3557:
3555:
3553:
3549:
3546:
3542:
3538:
3537:Tumor markers
3531:
3526:
3524:
3519:
3517:
3512:
3511:
3508:
3496:
3493:
3491:
3488:
3486:
3483:
3481:
3478:
3476:
3473:
3471:
3470:Thyroglobulin
3468:
3466:
3463:
3459:
3458:Glycophorin C
3456:
3454:
3451:
3449:
3446:
3445:
3444:
3441:
3439:
3436:
3434:
3431:
3429:
3426:
3424:
3421:
3419:
3416:
3414:
3411:
3409:
3406:
3404:
3401:
3399:
3396:
3394:
3391:
3389:
3386:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3351:
3349:
3346:
3344:
3341:
3340:
3338:
3334:
3324:
3321:
3320:
3318:
3316:
3312:
3306:
3303:
3301:
3298:
3296:
3293:
3292:
3290:
3288:
3284:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3239:
3236:
3235:
3233:
3231:
3227:
3221:
3218:
3216:
3213:
3212:
3210:
3208:
3204:
3200:
3194:
3191:
3189:
3186:
3184:
3181:
3180:
3178:
3176:
3172:
3168:
3165:
3163:
3162:Proteoglycans
3159:
3149:
3146:
3144:
3141:
3139:
3138:Peptidoglycan
3136:
3134:
3131:
3129:
3126:
3124:
3121:
3120:
3118:
3114:
3108:
3105:
3103:
3100:
3098:
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3078:
3075:
3073:
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3043:
3040:
3038:
3035:
3033:
3030:
3028:
3025:
3023:
3020:
3018:
3015:
3014:
3012:
3010:
3006:
3003:
3001:
2997:
2993:
2992:glycopeptides
2989:
2988:glycoproteins
2985:
2981:
2974:
2969:
2967:
2962:
2960:
2955:
2954:
2951:
2938:
2935:
2932:
2931:
2927:
2917:
2914:
2912:
2909:
2907:
2904:
2902:
2899:
2896:
2892:
2889:
2887:
2884:
2883:
2881:
2877:
2871:
2868:
2866:
2863:
2861:
2858:
2857:
2855:
2853:
2852:Serum albumin
2849:
2843:
2840:
2838:
2835:
2833:
2830:
2829:
2827:
2825:
2821:
2818:
2816:
2812:
2806:
2803:
2801:
2798:
2796:
2793:
2791:
2790:Thyroglobulin
2788:
2784:
2781:
2780:
2779:
2776:
2775:
2773:
2769:
2759:
2756:
2754:
2751:
2749:
2748:Microglobulin
2745:
2744:Macroglobulin
2742:
2739:
2735:
2732:
2731:
2729:
2725:
2719:
2716:
2715:
2713:
2711:
2707:
2697:
2694:
2692:
2689:
2687:
2684:
2682:
2679:
2677:
2674:
2672:
2669:
2668:
2666:
2660:
2653:
2650:
2648:
2645:
2644:
2642:
2638:
2633:
2630:
2628:
2624:
2613:
2609:
2605:
2602:
2598:
2597:
2595:
2589:
2583:
2580:
2577:
2576:Ceruloplasmin
2573:
2570:
2566:
2565:
2563:
2559:
2554:
2547:
2543:
2540:
2537:
2533:
2530:
2527:
2523:
2519:
2516:
2515:
2513:
2509:
2504:
2501:
2499:
2495:
2492:
2490:
2487:
2483:
2479:
2472:
2467:
2465:
2460:
2458:
2453:
2452:
2449:
2442:
2439:
2437:
2434:
2432:
2431:
2427:
2424:
2421:
2420:Thyroglobulin
2418:
2416:
2413:
2412:
2408:
2401:
2397:
2392:
2387:
2383:
2379:
2375:
2370:
2366:
2362:
2357:
2352:
2348:
2344:
2340:
2335:
2331:
2327:
2323:
2319:
2315:
2311:
2306:
2302:
2298:
2293:
2288:
2284:
2280:
2276:
2271:
2267:
2263:
2258:
2253:
2249:
2245:
2241:
2236:
2232:
2228:
2224:
2220:
2216:
2212:
2208:
2204:
2199:
2195:
2191:
2187:
2183:
2180:(1): 96–105.
2179:
2175:
2170:
2166:
2162:
2158:
2154:
2150:
2146:
2142:
2138:
2133:
2129:
2125:
2120:
2115:
2111:
2107:
2103:
2098:
2094:
2090:
2086:
2082:
2078:
2074:
2070:
2066:
2061:
2057:
2053:
2049:
2045:
2041:
2037:
2032:
2028:
2024:
2020:
2016:
2012:
2008:
2004:
2000:
1995:
1991:
1987:
1983:
1979:
1975:
1971:
1965:
1961:
1957:
1952:
1947:
1943:
1939:
1935:
1931:
1927:
1922:
1918:
1914:
1909:
1904:
1900:
1896:
1892:
1888:
1884:
1879:
1875:
1871:
1867:
1863:
1858:
1853:
1849:
1845:
1841:
1837:
1833:
1828:
1824:
1820:
1815:
1810:
1806:
1802:
1798:
1793:
1789:
1785:
1780:
1775:
1771:
1767:
1763:
1758:
1754:
1750:
1746:
1742:
1738:
1734:
1730:
1726:
1721:
1717:
1713:
1709:
1705:
1701:
1697:
1693:
1689:
1684:
1680:
1676:
1671:
1666:
1662:
1658:
1654:
1649:
1645:
1641:
1636:
1631:
1627:
1623:
1619:
1615:
1611:
1607:
1603:
1598:
1597:
1592:
1583:
1579:
1575:
1571:
1567:
1563:
1555:
1552:
1547:
1543:
1538:
1533:
1529:
1525:
1521:
1514:
1511:
1506:
1502:
1498:
1494:
1490:
1486:
1482:
1478:
1471:
1468:
1457:on 2010-05-13
1456:
1452:
1446:
1443:
1432:
1428:
1422:
1420:
1418:
1416:
1412:
1401:
1397:
1393:
1389:
1382:
1380:
1376:
1365:
1361:
1355:
1352:
1347:
1343:
1337:
1334:
1329:
1327:1-4160-2328-3
1323:
1319:
1312:
1310:
1306:
1301:
1297:
1291:
1288:
1283:
1279:
1273:
1270:
1266:
1262:
1257:
1255:
1253:
1249:
1245:
1241:
1236:
1234:
1232:
1228:
1221:
1219:
1217:
1213:
1205:
1203:
1201:
1197:
1193:
1189:
1184:
1177:
1175:
1172:
1170:
1166:
1160:
1153:
1148:
1146:
1142:
1140:
1135:
1133:
1129:
1126:
1118:
1114:
1110:
1103:
1101:
1099:
1095:
1091:
1087:
1083:
1078:
1076:
1072:
1067:
1063:
1059:
1056:
1052:
1048:
1044:
1043:Thyroglobulin
1032:
1027:
1023:
1019:
1016:
1012:
1005:
1003:
1000:
996:
992:
988:
985:
981:
977:
970:
968:
962:
958:
955:
949:
947:
941:
937:
934:
930:
923:
921:
915:
911:
908:
902:
900:
894:
890:
887:
885:RefSeq (mRNA)
883:
876:
875:
870:
866:
863:
857:
856:
851:
847:
844:
842:
838:
831:
830:
825:
821:
818:
812:
811:
806:
802:
799:
797:
793:
786:
785:
780:
776:
773:
767:
766:
761:
757:
754:
752:
748:
745:
742:
740:
737:
733:
730:
726:
722:
715:
711:
706:
700:
697:
695:
692:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
666:
664:
661:
660:
654:
651:
649:
646:
645:
643:
640:
639:
633:
630:
629:
627:
624:
623:
620:
619:Gene ontology
616:
612:
600:
595:
591:
584:
577:
572:
569:
567:
563:
555:
550:
539:
535:
531:
527:
523:
519:
515:
511:
508:thyroid gland
507:
503:
502:
499:
495:
490:
487:
477:
473:
469:
465:
461:
457:
453:
450:apex of heart
449:
445:
441:
440:
437:
433:
428:
425:
424:
421:
419:
415:
413:
412:
408:
407:
404:
402:
398:
394:
390:
386:
378:
373:
369:
365:
360:
350:
346:
339:
332:
326:
319:
311:
307:
303:
298:
294:
289:
285:
277:
272:
268:
264:
259:
249:
245:
238:
231:
225:
218:
214:
208:
204:
200:
195:
191:
186:
182:
178:
174:
170:
166:
162:
158:
154:
150:
146:
142:
134:
129:
122:
117:
112:
108:
103:
98:
97:thymoglobulin
94:
83:
80:
72:
62:
58:
52:
51:
45:
41:
37:
32:
23:
22:
16:
4831:
4830:
4812:
4754:
4727:2-Thiouracil
4693:
4649:Thiocyanates
4629:Perchlorates
4620:
4450:Liothyronine
4068:
4054:
4048:Testosterone
4040:
4028:Dysgerminoma
4026:
4012:
3998:
3979:
3965:
3760:S100 protein
3611:
3469:
3383:4-1BB ligand
3295:Fibromodulin
3000:Mucoproteins
2933:
2789:
2542:Antithrombin
2428:
2381:
2377:
2346:
2342:
2316:(1): 61–70.
2313:
2309:
2282:
2278:
2247:
2243:
2206:
2202:
2177:
2173:
2140:
2136:
2112:(1): 53–58.
2109:
2105:
2071:(1): 28–31.
2068:
2064:
2039:
2035:
2002:
1998:
1973:
1969:
1933:
1929:
1890:
1886:
1839:
1836:FEBS Letters
1835:
1804:
1800:
1769:
1765:
1728:
1724:
1691:
1687:
1660:
1656:
1609:
1605:
1565:
1561:
1554:
1527:
1523:
1513:
1480:
1476:
1470:
1459:. Retrieved
1455:the original
1445:
1434:. Retrieved
1430:
1403:. Retrieved
1391:
1367:. Retrieved
1363:
1354:
1345:
1336:
1317:
1299:
1290:
1281:
1272:
1209:
1206:Interactions
1185:
1181:
1173:
1165:tumor marker
1161:
1157:
1143:
1136:
1122:
1079:
1058:glycoprotein
1046:
1042:
1041:
964:
943:
917:
896:
872:
853:
827:
808:
782:
763:
743:
738:
528:spermatocyte
416:
409:
274:133,134,903
261:132,866,958
136:External IDs
75:
66:
55:Please help
47:
15:
4773:Propranolol
4755:Inhibitors:
4712:Methimazole
4702:Carbimazole
4694:Inhibitors:
4621:Inhibitors:
4589:Transporter
4554:Antagonists
4307:Cytokeratin
4245:Cathepsin D
3834:Factor VIII
3825:endothelium
3788:Lung cancer
3780:respiratory
3730:Astrocytoma
3712:Brain tumor
3495:Vitronectin
3490:Uteroglobin
3480:Transcortin
3453:Glycophorin
3423:Osteonectin
3408:Lactoferrin
3133:Orosomucoid
3123:Haptoglobin
2901:Parvalbumin
2891:Lactalbumin
2783:Lactoferrin
2734:Fibronectin
2691:Plasminogen
2671:Angiostatin
2652:Transferrin
2612:Haptoglobin
2601:Orosomucoid
2569:Transcortin
2430:endo-endo11
1049:) is a 660
532:granulocyte
454:skin of leg
375:66,722,570
362:66,542,602
114:Identifiers
69:August 2017
61:introducing
4851:Categories
4803:Iodine-131
4670:inhibitors
4525:Resmetirom
4385:modulators
4298:epithelium
3621:Calcitonin
3560:Neprilysin
3323:Syndecan 1
2870:Prealbumin
2832:Conalbumin
1461:2009-03-28
1436:2019-05-06
1405:2019-09-17
1369:2019-09-16
1267:, May 2017
1246:, May 2017
1222:References
1130:(T4) and
1075:N-terminus
420:(ortholog)
157:HomoloGene
4832:See also:
4707:Genistein
4510:KB-130015
4460:Thyroxine
4294:Carcinoma
3847:Digestive
3801:Enolase 2
3650:Enolase 2
3596:Endocrine
3433:Protein S
3428:Protein C
3403:Hemopexin
3393:Clusterin
3305:Keratocan
2837:Ovalbumin
2824:Egg white
2696:Properdin
2676:Hemopexin
2606:alpha-2 (
2599:alpha-1 (
2574:alpha-2 (
2567:alpha-1 (
2489:globulins
1477:Neurology
1196:euthyroid
1128:thyroxine
967:NP_033401
946:NP_003226
920:NM_009375
899:NM_003235
729:Orthologs
165:GeneCards
4818:Tyrosine
4808:Selenium
4732:Thiourea
4595:blockers
4520:MB-07811
4515:MB-07344
4423:Agonists
4393:Receptor
4284:Vimentin
4250:CA 27-29
3948:urinary/
3752:Melanoma
3552:Lymphoma
3252:Brevican
3247:Neurocan
3242:Aggrecan
3220:Perlecan
3215:Testican
3193:Versican
3188:Biglycan
3148:Ovomucin
2934:see also
2815:Albumins
2686:Factor H
2400:24617715
2231:34165624
2165:28315029
2027:24724872
1874:32367745
1753:35326294
1716:38620713
1679:12679418
1644:32025030
1582:10049727
1546:11294872
1505:21610036
1497:12601119
1400:25905405
1392:Endotext
1263:–
1242:–
1212:interact
1104:Function
1086:tyrosine
1015:Wikidata
708:Sources:
470:testicle
466:amygdala
4872:Thyroid
4641:(e.g.,
4631:(e.g.,
4540:VK-2809
4535:VK-0214
4505:KB-2611
4455:Liotrix
4399:ligands
4276:Sarcoma
4230:CA 15-3
4166:TMPRSS2
4062:Inhibin
3300:Lumican
3183:Decorin
2980:Protein
2758:Edestin
2532:alpha-2
2518:alpha-1
2508:serpins
2365:8797845
2330:8615697
2301:8530385
2266:8269951
2223:8094490
2194:7793989
2157:4043966
2128:3971976
2093:9234835
2085:3967888
2056:3681978
2019:3595599
1990:3211159
1960:3016640
1917:2991855
1866:2914619
1844:Bibcode
1823:2760035
1788:1939080
1745:1639210
1708:1371467
1635:7170718
1614:Bibcode
1265:Ensembl
1244:Ensembl
1098:colloid
1066:thyroid
1064:of the
1055:dimeric
841:UniProt
796:Ensembl
735:Species
714:QuickGO
504:trachea
395:pattern
253:8q24.22
121:Aliases
57:improve
4798:Iodine
4791:Others
4664:Enzyme
4614:
4500:KB-141
4336:Desmin
4151:SPINK1
4098:AFP-L3
3973:CA-125
3950:breast
3933:AFP-L3
3901:CA 242
3891:CA19-9
3863:CA19-9
3373:Avidin
3052:MUC5AC
2842:Avidin
2736:(fFN:
2663:other:
2592:other:
2398:
2363:
2328:
2299:
2264:
2229:
2221:
2203:Lancet
2192:
2163:
2155:
2126:
2091:
2083:
2054:
2025:
2017:
1988:
1958:
1951:311533
1948:
1915:
1908:321854
1905:
1872:
1864:
1821:
1786:
1751:
1743:
1714:
1706:
1677:
1642:
1632:
1606:Nature
1580:
1544:
1503:
1495:
1398:
1324:
1090:iodine
1001:search
999:PubMed
874:O08710
855:P01266
751:Entrez
566:BioGPS
540:atrium
520:embryo
145:188450
4561:1-850
4440:DITPA
4435:DIMIT
4255:hPG80
4212:NMP22
4189:NANOG
4171:hPG80
4156:GOLM1
4108:hPG80
4070:hPG80
3911:hPG80
3873:hPG80
3811:hPG80
3583:CD79a
3544:Blood
3336:Other
3267:CSPG5
3262:CSPG4
3116:Other
3107:MUC20
3102:MUC19
3097:MUC17
3092:MUC16
3087:MUC15
3082:MUC13
3077:MUC12
3057:MUC5B
3042:MUC3B
3037:MUC3A
3022:CD164
3009:Mucin
2906:Ricin
2879:Other
2727:Other
2486:Serum
2227:S2CID
2161:S2CID
2089:S2CID
2023:S2CID
1870:S2CID
1749:S2CID
1712:S2CID
1501:S2CID
1214:with
784:21819
744:Mouse
739:Human
710:Amigo
524:blood
418:Mouse
411:Human
358:Start
293:Mouse
257:Start
190:Human
153:98733
95:, or
42:, or
4545:ZYT1
4161:PCA3
4103:CD30
4089:βhCG
3987:CD30
3720:PCNA
3448:CD43
3363:CD70
3348:ADAM
3257:CD44
3072:MUC8
3067:MUC7
3062:MUC6
3047:MUC4
3032:MUC2
3027:MUC1
3017:CD43
2990:and
2396:PMID
2361:PMID
2326:PMID
2297:PMID
2262:PMID
2219:PMID
2190:PMID
2153:PMID
2124:PMID
2081:PMID
2052:PMID
2015:PMID
1986:PMID
1956:PMID
1913:PMID
1862:PMID
1819:PMID
1784:PMID
1741:PMID
1704:PMID
1675:PMID
1640:PMID
1578:PMID
1542:PMID
1493:PMID
1396:PMID
1322:ISBN
765:7038
401:Bgee
349:Band
310:Chr.
248:Band
207:Chr.
161:2430
141:OMIM
4743:DIO
4682:TPO
4607:NIS
4566:NH3
4411:THR
4056:GCT
4034:LDH
4020:hCG
4000:EST
3992:hCG
3578:CD3
2386:doi
2351:doi
2347:240
2318:doi
2314:327
2287:doi
2283:270
2252:doi
2248:218
2211:doi
2207:341
2182:doi
2178:320
2145:doi
2114:doi
2110:147
2073:doi
2044:doi
2040:196
2007:doi
2003:165
1978:doi
1946:PMC
1938:doi
1903:PMC
1895:doi
1852:doi
1840:242
1809:doi
1805:264
1774:doi
1770:266
1733:doi
1696:doi
1665:doi
1630:PMC
1622:doi
1610:578
1570:doi
1566:255
1532:doi
1528:276
1485:doi
1190:or
1051:kDa
371:End
270:End
173:OMA
149:MGI
4853::
3981:EC
3748:NC
3315:HS
3287:KS
3240::
3230:CS
3207:CS
3203:HS
3175:DS
3171:CS
2986::
2982:,
2610:,
2524:,
2394:.
2382:99
2380:.
2376:.
2359:.
2345:.
2341:.
2324:.
2312:.
2295:.
2281:.
2277:.
2260:.
2246:.
2242:.
2225:.
2217:.
2205:.
2188:.
2176:.
2159:.
2151:.
2141:71
2139:.
2122:.
2108:.
2104:.
2087:.
2079:.
2069:69
2067:.
2050:.
2038:.
2021:.
2013:.
2001:.
1984:.
1974:25
1972:.
1954:.
1944:.
1934:14
1932:.
1928:.
1911:.
1901:.
1891:13
1889:.
1885:.
1868:.
1860:.
1850:.
1838:.
1834:.
1817:.
1803:.
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1747:.
1739:.
1729:84
1727:.
1710:.
1702:.
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1690:.
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1655:.
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1608:.
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1576:.
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1499:.
1491:.
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1479:.
1429:.
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1378:^
1362:.
1344:.
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1298:.
1280:.
1251:^
1230:^
1218:.
1053:,
1047:Tg
712:/
377:bp
364:bp
276:bp
263:bp
171:;
169:TG
167::
163:;
159::
155:;
151::
147:;
143::
128:TG
105:TG
46:,
38:,
4672:)
4668:(
4645:)
4635:)
4597:)
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2972:e
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