Knowledge

Radiation treatment planning

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Galvin, James M; Ezzell, Gary; Eisbrauch, Avraham; Yu, Cedric; Butler, Brian; Xiao, Ying; Rosen, Isaac; Rosenman, Julian; Sharpe, Michael; Xing, Lei; Xia, Ping; Lomax, Tony; Low, Daniel A; Palta, Jatinder (April 2004), "Implementing IMRT in clinical practice: a joint document of the American Society
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Once the treatment planner has made an initial plan, the treatment planning system calculates the required monitor units to deliver a prescribed dose to a specific area, and the distribution of dose in the body this will create. The dose distribution in the patient is dependent on the anatomy and
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is less commonly used and reserved for cases where specific uptake studies can enhance planning target volume delineation. Modern treatment planning systems provide tools for multimodality image matching, also known as image coregistration or fusion. Treatment simulations are used to plan the
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utilise inverse planning to provide further improved dose distributions (i.e. better coverage of target tumours and sparing of healthy tissue). These methods are growing in use, particularly for cancers in certain locations which have been shown to derive the greatest benefits.
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In inverse planning a radiation oncologist defines a patient's critical organs and tumour, after which a planner gives target doses and importance factors for each. Then, an optimisation program is run to find the treatment plan which best matches all the input criteria.
97:(MLCs) lead to 3D conformal planning (3DCRT), categorised as a Level 2 technique by the European Dynarad consortium. 3DCRT uses MLCs to shape the radiotherapy beam to closely match the shape of a target tumour, reducing the dose to healthy surrounding tissue. 277:
Thariat, Juliette; Hannoun-Levi, Jean-Michel; Sun Myint, Arthur; Vuong, Te; Gérard, Jean-Pierre (27 November 2012). "Past, present, and future of radiotherapy for the benefit of patients".
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of the patient allows more accurate modelling of the behaviour of the radiation as it travels through the patient's tissues. Different dose calculation models are available, including
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Lahanas, M; Baltas, D; Giannouli, S (7 March 2003). "Global convergence analysis of fast multiobjective gradient-based dose optimization algorithms for high-dose-rate brachytherapy".
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images, often by hand and with manual calculations. Computerised treatment planning systems began to be used in the 1970s to improve the accuracy and speed of dose calculations.
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and minimising the dose to healthy tissue. The required decisions include how many radiation beams to use, which angles each will be delivered from, whether attenuating
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This type of planning is only sufficiently adept to handle relatively simple cases in which the tumour has a simple shape and is not near any critical organs.
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Intensity Modulated Radiation Therapy Collaborative Working Group (November 2001). "Intensity-modulated radiotherapy: current status and issues of interest".
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AlDuhaiby, Eman Z; Breen, Stephen; Bissonnette, Jean-Pierre; Sharpe, Michael; Mayhew, Linda; Tyldesley, Scott; Wilke, Derek R; Hodgson, David C (2012).
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planning involves selecting the appropriate catheter positions and source dwell times (in HDR brachytherapy) or seed positions (in LDR brachytherapy).
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Kolitsi, Zoi; Dahl, Olav; Van Loon, Ron; Drouard, Jean; Van Dijk, Jan; Ruden, Bengt Inge; Chierego, Giorgio; Rosenwald, Jean Claude (December 1997).
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In forward planning, the planner places beams into a radiotherapy treatment planning system that can deliver sufficient radiation to a
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Society and College of Radiographers; Institute of Physics and Engineering in Medicine; Royal College of Radiologists (2015),
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Radiotherapy Board - Intensity Modulated Radiotherapy (IMRT) in the UK: Current access and predictions of future access rates
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In contrast to the manual trial-and-error process of forward planning, inverse planning uses the optimiser to solve the
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beam modifiers such as wedges, specialized collimation, field sizes, tumor depth, etc. The information from a prior
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Optimization of Catheter Position and Dwell Time in Prostate HDR Brachytherapy using HIPO and Linear Programming
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geometric, radiological, and dosimetric aspects of the therapy using radiation transport simulations and
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Transition from 2-D Radiotherapy to 3-D Conformal and Intensity Modulated Radiotherapy IAEA-TECDOC-1588
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for Therapeutic Radiology and Oncology and the American Association of Physicists in Medicine.",
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Gintz, D; Latifi, K; Caudell, J; Nelms, B; Zhang, G; Moros, E; Feygelman, V (8 May 2016).
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be used, and which MLC configuration will be used to shape the radiation from each beam.
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Fraass, Benedick A. (1995). "The development of conformal radiation therapy".
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Karabis, A; Belloti, P; Baltas, D (2009). O. Dössel; W.C. Schlegel (eds.).
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provides excellent secondary image set for soft tissue contouring.
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Pereira, Gisele C.; Traughber, Melanie; Muzic, Raymond F. (2014).
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The more formal optimization process is typically referred to as
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In the early days of radiotherapy planning was performed on 2D
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International Journal of Radiation Oncology, Biology, Physics
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is often the primary image set for treatment planning while
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plan the appropriate external beam radiotherapy or internal
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(2004). 767:. 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Index

Treatment Planning System

radiotherapy
radiation oncologists
radiation therapist
medical physicists
medical dosimetrists
brachytherapy
cancer
x-ray
CT scans
Multileaf collimators
IMRT
VMAT
medical imaging
CT scan
magnetic resonance imaging
Positron emission tomography
optimization
intensity modulated radiation therapy
IMRT
megaelectronvolt
brachytherapy
dose-volume histograms

Optic nerve sheath meningioma
tumour
organs
wedges
CT scan

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