Knowledge (XXG)

Cancer treatment

Source πŸ“

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provided by the Center for Intramural Research. They found that black patients were 41% less likely to receive colorectal treatment and were more likely to be hospitalized in a teaching hospital with less certified physicians compared to white patients. Furthermore, black patients were more likely to be diagnosed with oncologic sequelae, which is a severity of the illness in result of poorly treated cancer. Lastly, for every 1,000 patients in the hospital, there were 137.4 black patient deaths and 95.6 white patient deaths.
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but if a new treatment proves effective or more effective than standard treatment, study patients who receive it may be among the first to benefit. There is no guarantee that a new treatment being tested or a standard treatment will produce good results. In children with cancer, a survey of trials found that those enrolled in trials were on average not more likely to do better or worse than those on standard treatment; this confirms that success or failure of an experimental treatment cannot be predicted.
329:. The effects of radiation therapy are localised and confined to the region being treated. Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and function properly. The goal of radiation therapy is to damage as many cancer cells as possible, while limiting harm to nearby healthy tissue. Hence, it is given in many fractions, allowing healthy tissue to recover between fractions. 1260:" refers to compounds used instead of conventional medicine. CAM use is common among people with cancer; a 2000 study found that 69% of cancer patients had used at least one CAM therapy as part of their cancer treatment. Most complementary and alternative medicines for cancer have not been rigorously studied or tested. Some alternative treatments which have been investigated and shown to be ineffective continue to be marketed and promoted. 1239:
and allowing for angiogenesis. Studies are currently being done with "Lectin affinity plasmapheresis" (LAP), LAP is a blood filtration method which selectively targets the tumor based exosomes and removes them from the bloodstream. It is believed that decreasing the tumor-secreted exosomes in a patient's bloodstream will slow down progression of the cancer while at the same time increasing the patients own immune response.
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factor in high death rates. Minorities are more likely to receive inadequate treatment while white patients are more likely to receive efficient treatments in a timely manner. Having satisfactory treatment in a timely manner can increase the patient's likelihood of survival. It has been shown that chances of survival are significantly greater for white patients than for African American patients.
708:, cancer cells can commandeer this physiological regulatory system to "put a brake" on the anti-cancer immune response and evade immune surveillance. 2018 Nobel Prize in medicine is awarded to Dr. James Allison of University of Texas MD Anderson Cancer Center in U.S. and Dr. Tasuku Honjo Kyoto University in Japan for their contributions in advance of PD-1 and CTLA-4 immune checkpoint therapy. 820: 1140:
inflict pain but also cause patients to become mentally exhausted and want to give up. For a lot of reasons including these, hospitals offer many types of therapy and mental healing. Some of these include yoga, meditation, communication therapy, and spiritual ideas. All of these are meant to calm and relax the mind, or to give hope for the patients that may feel drained.
278:. In breast cancer, the survival rate of patients who receive neoadjuvant chemotherapy are no different from those who are treated following surgery. Giving chemotherapy earlier allows oncologists to evaluate the effectiveness of the therapy, and may make removal of the tumor easier. However, the survival advantages of neoadjuvant treatment in lung cancer are less clear. 1374:
this explains why fewer African Americans receive treatment. Others suggest that African Americans seek more treatment than whites and that it is simply a lack of the resources available to them. In this case, analyzing these studies will identify the treatment disparities and look to prevent them by discovering potential causes of these disparities.
1199:, also called research studies, test new treatments in people with cancer. The goal of this research is to find better ways to treat cancer and help cancer patients. Clinical trials test many types of treatment such as new drugs, new approaches to surgery or radiation therapy, new combinations of treatments, or new methods such as 808:
uncertain whether improved outcomes with exercise are correlated or causative, the benefit-risk ratio of including exercise as part of cancer treatment is large, as exercise has further benefits (e.g. cardiovascular, mental health) without major risks, although there is a small risk of overuse injury if added too aggressively.
412:(TBI). This treatment ablates the bone marrow, and hence the body's ability to recover and repopulate the blood. For this reason, bone marrow, or peripheral blood stem cell harvesting is carried out before the ablative part of the therapy, to enable "rescue" after the treatment has been given. This is known as autologous 1177:
at home, or in a dedicated hospice institution, for a person with an advanced illness termed as terminal. Untreated cancer will prove terminal, and sometimes a choice is made to forgo treatment and its unpleasant side effects, and opt instead for hospice care. Hospice care aims to provide support for
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Cancer patients undergo many obstacles and one of these includes mental strain. It is very common for cancer patients to become stressed, overwhelmed, uncertain, and even depressed. The use of chemo is a very harsh treatment causing the cells of the body to die. Physical effects like this do not only
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model of cancer progression, tumors grow locally, then spread to the lymph nodes, then to the rest of the body. This has given rise to the popularity of local-only treatments such as surgery for small cancers. Even small localized tumors are increasingly recognized as possessing metastatic potential.
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Among lung cancer patients, stigma, shame, social isolation, and discrimination are common. Such patients are sometimes told that they deserve cancer because of their smoking. Those patients also may have feelings of guilt for having cancer. Stigma in cervical cancer was predominantly driven by fear
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An article in a breast cancer journal analyzed the disparities of breast cancer treatments in the Appalachian Mountains. African American women were found to be three times more likely to die compared to Asians and two times more likely to die compared to white women. According to the study, African
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Cancer is a significant issue that is affecting the world. Specifically in the U.S., 1,735,350 new cases of cancer, and 609,640 deaths were expected by the end of 2018. Adequate treatment can prevent many cancer deaths but there are racial and social disparities in treatments which has a significant
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Exosomes, secreted by tumors, are also believed to be responsible for triggering programmed cell death (apoptosis) of immune cells; interrupting T-cell signaling required to mount an immune response; inhibiting the production of anti-cancer cytokines, and has implications in the spread of metastasis
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Decreased muscle strength is a common side effect to many different cancer treatments. Because of this, exercise is very important especially in the first year after treatment. It has been shown that yoga, water exercise, and pilates can improve the emotional well-being and quality of life of breast
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can be associated with continuing tissue damage due to the disease process, or the treatment (i.e. surgery, radiation, chemotherapy). There is always a role for environmental factors and affective disturbances in the genesis of pain behaviors, However these are not usually the predominant etiologic
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surrounding the tumor. Radionuclides which are attached to these peptides (e.g. RGDs) eventually kill the cancer cell if the nuclide decays in the vicinity of the cell. Especially oligo- or multimers of these binding motifs are of great interest, since this can lead to enhanced tumor specificity and
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Since chemotherapy affects the whole body, it can have a wide range of side effects. Patients often find that they start losing their hair since the drugs that are combatting the cancer cells also attack the cells in the hair roots. This powerful treatment can also lead to fatigue, loss of appetite,
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infection and cervical cancer were stigmatized due to the perception that they arise from reckless behavior such as having multiple sexual partners or neglecting screening. Resilience may be a potent protective mechanism against stigmatization. Resilience in context of cancer treatment is patient's
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and an adjuvant trial found that there was no evidence to support racial differences in treating colorectal cancer. However, two studies suggested that African American patients received less satisfactory and poorer quality treatment compared to white patients. One of these studies specifically was
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The treatment of cancer has undergone evolutionary changes as understanding of the underlying biological processes has increased. Tumor removal surgeries have been documented in ancient Egypt, hormone therapy and radiation therapy were developed in the late 19th century. Chemotherapy, immunotherapy
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Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, Scott CL, Meier W, Shapira-Frommer R, Safra T, Matei D, Fielding A, Spencer S, Dougherty B, Orr M, Hodgson D, Barrett JC, Matulonis U (July 2014). "Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous
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or no insurance compared to other races. The location of the health care facility also plays a role in why African Americans receive less treatment in comparison to other races. However, some studies say that African Americans do not trust doctors and do not always seek the help they need and that
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are lipid-covered microvesicles shed by solid tumors into bodily fluids, such as blood and urine. Current research is being done attempting to use exosomes as a detection and monitoring method for a variety of cancers. The hope is to be able to detect cancer with a high sensitivity and specificity
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Patients who take part may be helped personally by the treatment they receive. They get up-to-date care from cancer experts, and they receive either a new treatment being tested or the best available standard treatment for their cancer. At the same time, new treatments also may have unknown risks,
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Advance care planning (ACP) can help a person to decide for themself their future care wishes as they approach end of life. ACP helps adults at any stage of health to decide, and record in writing, their wishes for medical treatment preferences, and future wants, preferably as previously discussed
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Stage 4 patients only undergo surgery if it is for the prevention of the cancer, along with pain relief. If the pain continues with these two options, the doctor might recommended radiation therapy. The main treatment strategy is chemotherapy due to how aggressive the cancer becomes in this stage,
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The annual average mortality of patients with colorectal cancer between 1992 and 2000 was 27 and 18.5 per 100,000 white patients and 35.4 and 25.3 per 100,000 black patients. In a journal that analyzed multiple studies testing racial disparities when treating colorectal cancer found contradicting
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has been proven to directly detect melanoma derived exosomes from fluid samples. Previously, exosomes had been measured by total protein content in purified samples and by indirect immunomodulatory effects. ELLSA directly measures exosome particles in complex solutions, and has already been found
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From these studies, researchers have noted that there are definite disparities in the treatment of cancer, specifically who has access to the best treatment and can receive it in a timely manner. This eventually leads to disparities between who dies from cancer and who is more likely to survive.
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Stage 3, is where the cancer has spread all throughout the lymph nodes but not yet to other organs or body parts. When getting to this stage, Surgery is conducted on the colon and lymph nodes, then the doctor orders Chemotherapy (FOLFOX or CapeOx) to treat the colon cancer in the location needed
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A clinical trial is one of the final stages of a long and careful cancer research process. The search for new treatments begins in the laboratory, where scientists first develop and test new ideas. If an approach seems promising, the next step may be testing a treatment in animals to see how it
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Exercise prescription is becoming a mainstream adjunct treatment for cancer, based on studies which show that exercise (compared to no exercise) is associated with reduced recurrence rates, improved mortality outcomes, reduction of side effects from traditional cancer treatments. Although it is
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and health care consumption can be concerns and may need to be addressed for the person to feel comfortable taking the medications required to control his or her symptoms. The typical strategy for cancer pain management is to get the patient as comfortable as possible using the least amount of
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A common disorder experienced by people that have survived cancer treatments is insomnia. Almost 60% of cancer survivors experience insomnia, and if it is not treated properly it can have long term effects on physiological and physical health. Insomnia is defined as dissatisfaction with sleep
1256:(CAM) treatments are the diverse group of medical and health care systems, practices, and products that are not part of conventional medicine and have not been shown to be effective. "Complementary medicine" refers to methods and substances used along with conventional medicine, while " 340:. Radiation dose to each site depends on a number of factors, including the radio sensitivity of each cancer type and whether there are tissues and organs nearby that may be damaged by radiation. Thus, as with every form of treatment, radiation therapy is not without its side effects. 1391:
physiological and psychological capacity to effectively adapt, recover, and maintain optimal functioning in the face of the medical challenges. It encompasses the ability to cope with and overcome adversity, maintain emotional well-being, and promote overall health and healing.
369:("anticancer drugs") that can destroy cancer cells. Chemotherapy can be given in a variety of ways such as injections into the muscles, skin, artery, or vein, or it could even be taken by mouth in the form of a pill. In current usage, the term "chemotherapy" usually refers to 231:
for non-small cell lung cancer. The goal of the surgery can be either the removal of only the tumor, the entire organ, or part of the organ. A single cancer cell is invisible to the naked eye but can regrow into a new tumor, a process called recurrence. For this reason, the
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for use in BRCA-associated ovarian cancer that had previously been treated with chemotherapy. The FDA, in 2016, also approved the PARP inhibitor rucaparib to treat women with advanced ovarian cancer who have already been treated with at least two chemotherapies and have a
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Targeted therapy, which first became available in the late 1990s, has had a significant impact in the treatment of some types of cancer, and is currently a very active research area. This constitutes the use of agents specific for the deregulated proteins of cancer cells.
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arises when a combination of deficiencies in the expression of two or more genes leads to cell death, whereas a deficiency in only one of these genes does not. The deficiencies can arise through mutations, epigenetic alterations or inhibitors of one or both of the genes.
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affects cancer in a living being and whether it has harmful effects. Of course, treatments that work well in the lab or in animals do not always work well in people. Studies are done with cancer patients to find out whether promising treatments are safe and effective.
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The cause of these disparities is generally that African Americans have less medical care coverage, insurance and access cancer centers than other races. For an example, black patients with breast cancer and colorectal cancer were shown to be more likely to have
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are used has been in practice in Japan since 1990. NK cells and TCs primarily kill the cancer cells when they are developed. This treatment is given together with the other modes of treatment such as surgery, radiotherapy or chemotherapy and termed
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Ding X, Ray Chaudhuri A, Callen E, Pang Y, Biswas K, Klarmann KD, Martin BK, Burkett S, Cleveland L, Stauffer S, Sullivan T, Dewan A, Marks H, Tubbs AT, Wong N, Buehler E, Akagi K, Martin SE, Keller JR, Nussenzweig A, Sharan SK (August 2016).
389:, while normal cells generally can. Hence, chemotherapy has the potential to harm healthy tissue, especially those tissues that have a high replacement rate (e.g. intestinal lining). These cells usually repair themselves after chemotherapy. 347:
from exposure of salivary glands to radiation, resulting in decreased saliva secretion. Post therapy, the salivary glands will resume functioning but rarely in the same fashion. Dry mouth caused by radiation can be a permanent problem.
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and newer targeted therapies are products of the 20th century. As new information about the biology of cancer emerges, treatments will be developed and modified to increase effectiveness, precision, survivability, and quality of life.
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when the child is viable in order to begin a more aggressive cancer treatment, or, if the cancer is malignant enough that the mother is unlikely to be able to wait that long, to perform an abortion in order to treat the cancer.
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Even if a drug has been tested as not crossing the placenta to reach the child, some cancer forms can harm the placenta and make the drug pass over it anyway. Some forms of skin cancer may even metastasize to the child's body.
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American women are at a survival disadvantage compared to other races. Black women are also more likely to receive less successful treatment than white women by not receiving surgery or therapy. Furthermore, the US
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Chahine S, Urquhart R (October 2019). "A cross-sectional population-based survey looking at the impact of cancer survivorship care plans on meeting the needs of cancer survivors in the posttreatment stage".
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Stage 2 patients undergoes removing nearby lymph nodes, but depending on what the doctor says, the patent might have to undergo chemotherapy after surgery (if the cancer is at higher risk of coming back).
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Because some drugs work better together than alone, two or more drugs are often given at the same time. This is called "combination chemotherapy"; most chemotherapy regimens are given in a combination.
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Piazza MF, Galletta M, Portoghese I, Pilia I, Ionta MT, Contu P, Mereu A, Campagna M (August 2017). "Meeting psychosocial and health information needs to ensure quality of cancer care in outpatients".
385:. Most forms of chemotherapy target all rapidly dividing cells and are not specific to cancer cells, although some degree of specificity may come from the inability of many cancer cells to repair 1056:
of cancer patients, and plays an important role in the decision whether the patient is able to undergo other treatments. In general, doctors have the therapeutic skills to reduce pain including,
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The growth of some cancers can be inhibited by providing or blocking certain hormones. Common examples of hormone-sensitive tumors include certain types of breast and prostate cancers. Blocking
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via detection of specific exosomes in the blood or urine. The same process can also be used to more accurately monitor a patient's treatment progress. Enzyme linked lectin specific assay or
704:(PD-1). Under normal conditions, the immune system utilizes checkpoint proteins as negative feedback mechanisms to return to homeostasis once pathogens have been cleared from the body. In a 1287:
Radiation therapy is out of the question, and chemotherapy always poses the risk of miscarriage and congenital malformations. Little is known about the effects of medications on the child.
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Li L, Hobson L, Perry L, Clark B, Heavey S, Haider A, Sridhar A, Shaw G, Kelly J, Freeman A, Wilson I, Whitaker H, Nurmemmedov E, Oltean S, Porazinski S, Ladomery M (15 September 2020).
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High-energy therapeutic ultrasound could increase higher-density anti-cancer drug load and nanomedicines to target tumor sites by 20x fold higher than traditional target cancer therapy.
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Li S, Wang X, Wang M, Jiang Y, Mai Q, Wu J, Ye Z (October 2023). "Association between stigma and sleep quality in patients with breast cancer: A latent profile and mediation analysis".
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may be therapeutically beneficial. Although the side effects from hormone therapy vary depending on the type, patients can experience symptoms such as hot flashes, nausea, and fatigue.
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Ryan SL, Beard S, Barr MP, Umezawa K, Heavey S, Godwin P, Gray SG, Cormican D, Finn SP, Gately KA, Davies AM, Thompson EW, Richard DJ, O'Byrne KJ, Adams MN, Baird AM (September 2019).
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Agrelo R, Cheng WH, Setien F, Ropero S, Espada J, Fraga MF, Herranz M, Paz MF, Sanchez-Cespedes M, Artiga MJ, Guerrero D, Castells A, von Kobbe C, Bohr VA, Esteller M (June 2006).
857:), and a compensating DNA repair pathway is inhibited, then the tumor cells may be killed by synthetic lethality. Non-tumorous cells, with the initial pathway intact, can survive. 182:
is involved when the prognosis is poor and the cancer termed as terminal. There are many types of cancer, and many of these can be successfully treated if detected early enough.
3603:"Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group" 4339:, Glaefke G, Moe R, Bergner M, Rodenbaugh J (1989). "Treatment Modality and Quality Differences for Black and White Breast-Cancer Patients Treated in Community Hospitals". 236:
will examine the surgical specimen to determine if a margin of healthy tissue is present, thus decreasing the chance that microscopic cancer cells are left in the patient.
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Shugarman LR, Mack K, Sorbero ME, Tian H, Jain AK, Ashwood JS, Asch SM (2009). "Race and Sex Differences in the Receipt of Timely and Appropriate Lung Cancer Treatment".
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also noted uncontrolled cancer pain as a worldwide problem and established a "ladder" as a guideline for how practitioners should treat pain in patients who have cancer
670:. For this reason, allogeneic HSCT leads to a higher cure rate than autologous transplantation for several cancer types, although the side effects are also more severe. 1533: 666:) from a genetically non-identical donor can be considered a form of immunotherapy, since the donor's immune cells will often attack the tumor in a phenomenon known as 1787: 1431: 3694: 3723: 509:; PDT can also be useful in removing traces of malignant tissue after surgical removal of large tumors. In February 2019, medical scientists announced that 697: 2782:
Cormie P, Zopf EM, Zhang X, Schmitz KH (1 January 2017). "The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects".
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Peoples AR, Garland SN, Pigeon WR, Perlis ML, Wolf JR, Heffner KL, Mustian KM, Heckler CE, Peppone LJ, Kamen CS, Morrow GR, Roscoe JA (15 January 2019).
3939:, Greisinger A, Singletary SE (July 2000). "Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology". 1052:
Although the control of the symptoms of cancer is not typically thought of as a treatment directed at the cancer, it is an important determinant of the
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Ichim TE, Zhong Z, Kaushal S, Zheng X, Ren X, Hao X, Joyce JA, Hanley HH, Riordan NH, Koropatnick J, Bogin V, Minev BR, Min WP, Tullis RH (July 2008).
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are continuously under development. In 2023 it was estimated that one in five people will be diagnosed with cancer at some point in their lifetime.
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panel identified breast cancer treatments, given to black women, as inappropriate and not adequate compared to the treatment given to white women.
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Historically, doctors were reluctant to prescribe narcotics to terminal cancer patients due to addiction and respiratory function suppression. The
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Knapp-Oliver S, Moyer A (2012). "Causal Attributions Predict Willingness to Support the Allocation of Funding to Lung Cancer Treatment Programs".
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factors in patients with cancer pain. Some patients with severe pain associated with cancer are nearing the end of their lives, but in all cases,
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The primary goal of cancer treatment is to either cure the cancer by its complete removal, or to considerably prolong the life of the individual.
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Ong L, Visser M, Lammes F, de Haes J (September 2000). "Doctor–Patient communication and cancer patients' quality of life and satisfaction".
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As a consequence of the difficulties to properly diagnose and treat cancer during pregnancy, the alternative methods are either to perform a
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3081:"FDA approves Lynparza to treat advanced ovarian cancer: First LDT companion diagnostic test also approved to identify appropriate patients" 1382:
Despite recognition of improvements in outcomes, visceral fear of the disease is ubiquitous, and people may have to struggle to control it.
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Kennedy RD, D'Andrea AD (August 2006). "DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes".
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is the most common type of fetal tumor, and usually is benign. In some cases these are surgically treated while the fetus is still in the
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Taylor DD, Gercel-Taylor C (July 2008). "MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer".
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gene promoters, so that WRN protein expression was high. Irinotecan was more strongly beneficial for patients with hypermethylated
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of social judgment and rejection, self-blame, and shame, with notable negative influences from gender and social norms, as both
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Heavey S, Cuffe S, Finn S, Young V, Ryan R, Nicholson S, Leonard N, McVeigh N, Barr M, O'Byrne K, Gately K (29 November 2016).
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Stage 1, depending on the location of the cancer in the colon and lymph nodes, the patient undergoes surgery just like Stage 0.
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Peterson CE, Silva A, Goben AH, Ongtengco NP, Hu EZ, Khanna D, Nussbaum ER, Jasenof IG, Kim SJ, Dykens JA (December 2021).
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Holmes L, Opara F, Hossain J (2010). "A Five-Year Breast Cancer-Specific Survival Disadvantage of African American Women".
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are drugs to suppress nausea and vomiting. These are very commonly used in patients with cancer-related symptoms. Improved
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duration or quality and difficulties initiating or maintaining sleep. Insomnia can heavily reduce one's quality of life.
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2057:"Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer" 717: 453: 109: 4393:
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domains on mutated, overexpressed, or otherwise critical proteins within the cancer cell. Prominent examples are the
1851: 377:(see below). Chemotherapy drugs interfere with cell division in various possible ways, e.g. with the duplication of 5021: 1299: 650: 322: 4226:
Ball JK, Elixhauser A (September 1996). "Treatment Differences Between Blacks and Whites with Colorectal Cancer".
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capable of detecting exosomes from other sources, including ovarian cancer and tuberculosis-infected macrophages.
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Surgery may be performed before or after other forms of treatment. Treatment before surgery is often described as
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specialists can assist oncologists and primary care practitioners with exercise prescription in cancer patients.
440: 3310:"Acupuncture Versus Cognitive Behavioral Therapy for Insomnia in Cancer Survivors: A Randomized Clinical Trial" 2986:
ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial".
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Heavey S, O'Byrne KJ, Gately K (April 2014). "Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC".
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Cancer treatment needs to be selected to do least harm to both the woman and her embryo/fetus. In some cases a
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to fight the tumor. Contemporary methods for generating an immune response against tumors include intravesical
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Christensen JF, Simonsen C, Hojman P (13 December 2018). "Exercise Training in Cancer Control and Treatment".
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Sivaraman G, Pandian A, Baskar S, Senthil K, Senthilnagarajan R, Srinivasan V, Dedeepiya V, Abraham S (2008).
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peptides to induce a specific immune response against prostate-derived cells. It gained FDA approval in 2010.
148:. Most commonly cancer treatment involves a series of separate therapies such as chemotherapy before surgery. 3601:
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Garland SN, Xie SX, DuHamel K, Bao T, Li Q, Barg FK, Song S, Kantoff P, Gehrman P, Mao JJ (1 December 2019).
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Heavey S, Godwin P, Baird AM, Barr MP, Umezawa K, Cuffe S, Finn SP, O'Byrne KJ, Gately K (10 October 2014).
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is a very common symptom of cancer, and there are a number of approaches put forward for helping with this.
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is often an important additional treatment. In certain cancers, administration of hormone agonists, such as
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Stage 0, is where the patient is required to undergo surgery to remove the polyp (American Cancer Society).
497:(PDT) is a ternary treatment for cancer involving a photosensitizer, tissue oxygen, and light (often using 3983: 1128: 748: 743: 705: 409: 149: 1506: 321:) within the cells that can in turn damage the DNA. Radiation therapy can be administered externally via 4972:"Radiation Therapy for Brain Cancer | CTCA." CancerCenter.com. N.p., 1 January 0001. Web. 21 March 2017. 1932: 1121:
movement, has engendered more widespread support for preemptive pain treatment for cancer patients. The
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Radiation therapy may be used to treat almost every type of solid tumor, and may also be used to treat
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Morin CM, Drake CL, Harvey AG, Krystal AD, Manber R, Riemann D, Spiegelhalder K (3 September 2015).
3096:"Press Announcements - FDA grants accelerated approval to new treatment for advanced ovarian cancer" 1936: 1224: 460:
which specifically binds to a protein on the surface of the cancer cells. Examples include the anti-
4476:"Public perceptions of cancer: a qualitative study of the balance of positive and negative beliefs" 2196:
Luszczak S, Kumar C, Sathyadevan VK, Simpson BS, Gately KA, Whitaker HC, Heavey S (December 2020).
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Northouse LL (1 September 2012). "Helping Patients and Their Family Caregivers Cope With Cancer".
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has increased specifically in response to the symptom control needs for these groups of patients.
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Knapp-Oliver S, Moyer A (2009). "Visibility and the Stigmatization of Cancer: Context Matters".
2016:"Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours" 4953: 4924: 4884: 4847: 4788: 4739: 4696: 4676: 4630: 4554: 4505: 4418: 4364: 4314: 4269: 4243: 4195: 4144: 4061: 4001: 3956: 3879: 3836: 3756: 3686: 3667: 3632: 3526: 3508: 3469: 3451: 3404: 3396: 3347: 3329: 3282: 3247: 3159: 3061: 3003: 2967: 2926: 2883: 2840: 2799: 2756: 2721: 2672: 2566: 2517: 2468: 2429: 2377: 2326: 2269: 2227: 2178: 2129: 2086: 2037: 1996: 1969: 1906: 1769: 1712: 1662:
Subotic S, Wyler S, Bachmann A (August 2012). "Surgical Treatment of Localised Renal Cancer".
1618: 1411: 1406: 1219: 1013: 948: 911: 813: 756: 693: 298: 287: 264: 145: 105: 55: 47: 849:.) This DNA repair defect either may be due to mutation or, often, epigenetic silencing (see 4945: 4916: 4876: 4839: 4778: 4731: 4688: 4657: 4620: 4612: 4581: 4544: 4536: 4525:"Multilevel Opportunities to Address Lung Cancer Stigma across the Cancer Control Continuum" 4495: 4487: 4456: 4402: 4348: 4235: 4179: 4128: 4051: 4043: 3993: 3948: 3871: 3826: 3816: 3748: 3678: 3659: 3622: 3614: 3516: 3500: 3459: 3443: 3386: 3378: 3337: 3321: 3309: 3274: 3239: 3149: 3139: 3051: 3043: 2995: 2957: 2918: 2875: 2830: 2791: 2748: 2711: 2703: 2662: 2652: 2556: 2507: 2499: 2419: 2409: 2367: 2357: 2316: 2308: 2261: 2217: 2209: 2168: 2160: 2121: 2076: 2068: 2027: 1986: 1978: 1898: 1759: 1751: 1702: 1671: 1608: 1600: 1456: 1310: 678: 552: 479: 425: 256: 168: 156: 113: 2488:"CTLA-4 and PD-1 Pathways: Similarities, Differences, and Implications of Their Inhibition" 1019:
There are five different stages of colon cancer, and these five stages all have treatment:
5031: 4992: 4903:"How Does Radiation Therapy Work?" American Cancer Society. N.p., n.d. Web. 21 March 2017. 3727: 1481: 1303: 1231: 1174: 1114: 1061: 1053: 982: 642: 630: 540: 518: 179: 4975:"Radiation Therapy for Cancer." National Cancer Institute. N.p., n.d. Web. 21 March 2017. 1178:
the person's medical, emotional, social, practical, psychological, and spiritual needs.
981:
gene in patients with colon cancer. In a 2006 study, 45 patients had colonic tumors with
531:
Targeted therapies under pre-clinical development as potential cancer treatments include
4056: 4031: 3135: 3039: 2552: 2457:"Autologous Immune Enhancement therapy for Advanced Carcinoma of Pancreas-A Case Report" 1110:
medications possible, even if that means using opioids, surgery, and physical measures.
1105:
therapies should be used to control the pain. Issues such as the social stigma of using
4625: 4600: 4549: 4524: 4500: 4475: 3936: 3831: 3804: 3627: 3602: 3521: 3488: 3464: 3431: 3342: 3154: 3119: 3056: 3023: 2716: 2691: 2667: 2640: 2512: 2487: 2424: 2397: 2372: 2345: 2321: 2296: 2222: 2197: 2173: 2148: 2081: 2056: 1991: 1964: 1764: 1739: 1613: 1588: 1422:
Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries
1196: 923: 866: 790: 646: 626: 606: 597:
refers to a diverse set of therapeutic strategies designed to induce the patient's own
589: 240: 160: 125: 3278: 3243: 2999: 2456: 1561: 5015: 4987: 4896: 4800: 4751: 4708: 4661: 4585: 4352: 4239: 3120:"Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer" 2895: 2852: 2639:
Al-Khayri JM, Sahana GR, Nagella P, Joseph BV, Alessa FM, Al-Mssallem MQ (May 2022).
2281: 2098: 1918: 1845: 598: 326: 318: 224: 171:
can help to determine the type of cancer, and indicate the best therapy. A number of
137: 4965: 4859: 4376: 4207: 4156: 4013: 3416: 3294: 2768: 2707: 2441: 1724: 1589:"Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges" 1273:
The incidence of pregnancy-associated cancer has risen due to the increasing age of
571: 4767:"Resilience and related factors in colorectal cancer patients: A systematic review" 4430: 3891: 1872: 1200: 772: 752: 727: 638: 522: 362: 357: 293: 133: 101: 96:, with each cancer type needing its own specific treatment. Treatments can include 17: 3432:"Cognitive Behavioral Therapy for Insomnia Reduces Depression in Cancer Survivors" 2265: 2032: 2015: 1965:"Nucleus-Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy" 1815: 4880: 4132: 3875: 2962: 2945: 2503: 1675: 4692: 4677:"Stigma and cervical cancer prevention: A scoping review of the U.S. literature" 4491: 4336: 4332: 3952: 3805:"Exosomes as a tumor immune escape mechanism: possible therapeutic implications" 3682: 3663: 3618: 1941: 1097: 1087: 1083: 1047: 764: 731: 663: 506: 465: 317:. Radiation therapy can either damage DNA directly or create charged particles ( 306: 275: 4920: 4843: 4783: 4766: 4735: 4540: 4523:
Hamann HA, Ver Hoeve ES, Carter-Harris L, Studts JL, Ostroff JS (August 2018).
4047: 4032:"The radiologist's role in a multidisciplinary approach to cancer in pregnancy" 3124:
Proceedings of the National Academy of Sciences of the United States of America
2561: 2536: 2125: 1889:
Dolmans DE, Fukumura D, Jain RK (May 2003). "Photodynamic therapy for cancer".
1534:"FDA approves olaparib for adjuvant treatment of high-risk early breast cancer" 823:
Walking is usually an excellent exercise option as an adjunct cancer treatment.
763:
into distal tissues. There are many approved angiogenesis inhibitors including
4406: 4183: 4170:
Bigby JA, Holmes MD (2005). "Disparities across the Breast Cancer Continuum".
3997: 3391: 2657: 2213: 2198:"PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer" 2164: 2072: 1604: 1102: 1091: 1079: 966: 819: 760: 656: 610: 536: 532: 386: 382: 366: 248: 244: 220: 216: 204: 4616: 4460: 3512: 3504: 3455: 3400: 3366: 3333: 2922: 2879: 2835: 2818: 2247:"Targeting NF-ΞΊB-mediated inflammatory pathways in cisplatin-resistant NSCLC" 3144: 2866:
Orchard JW (April 2020). "Prescribing and dosing exercise in primary care".
2795: 2362: 1274: 1075: 1067: 778: 469: 447: 401: 344: 252: 239:
In addition to removal of the primary tumor, surgery is often necessary for
4957: 4949: 4928: 4888: 4851: 4792: 4743: 4700: 4634: 4558: 4509: 4422: 4318: 4283: 4199: 4148: 4065: 4005: 3960: 3919: 3883: 3840: 3821: 3760: 3752: 3690: 3671: 3636: 3530: 3473: 3408: 3351: 3286: 3251: 3163: 3065: 3007: 2971: 2930: 2887: 2844: 2803: 2760: 2725: 2676: 2570: 2521: 2472: 2433: 2381: 2330: 2273: 2231: 2182: 2133: 2090: 2041: 2000: 1982: 1910: 1773: 1716: 1622: 207:) to other sites, complete surgical excision is usually impossible. In the 4368: 4247: 3974:
Vickers A (2004). "Alternative cancer cures: "unproven" or "disproven"?".
3778:"Aethlon Medical Announces Data Against Metastatic Melanoma - Sep 9, 2010" 3700:. If this is an intentional citation to a retracted paper, please replace 3325: 2414: 3382: 2752: 2346:"Targeting Nuclear Factor-Kappa B to Overcome Resistance to Chemotherapy" 1370: 1323: 1071: 919: 853:). If this DNA repair defect is in one of seven DNA repair pathways (see 768: 723: 622: 614: 560: 486:
as "homing devices" which can bind to cell surface receptors or affected
461: 457: 443: 405: 337: 333: 129: 92:
are a wide range of treatments available for the many different types of
60: 4414: 4310: 4191: 4140: 4030:
Harwin J, Jha P, Post A, Silverstein J, Van Loon K, Poder L (May 2023).
3047: 2297:"Strategic targeting of the PI3K–NFΞΊB axis in cisplatin-resistant NSCLC" 79: 4360: 4093:(in German). Curado. Associated Press. 20 February 2009. Archived from 2946:"Synthetic lethality: exploiting the addiction of cancer to DNA repair" 1277:. Cancers may also be detected incidentally during maternal screening. 1170: 1118: 1106: 1094:
have made aggressive treatments much more feasible in cancer patients.
514: 510: 483: 373:
drugs which affect rapidly dividing cells in general, in contrast with
200: 97: 3447: 2312: 1755: 1740:"Cancer and radiation therapy: current advances and future directions" 1153:
has been seen to reduce insomnia and depression for cancer survivors.
845:
Cancer cells are frequently deficient in a DNA repair gene. (Also see
633:
are the subject of intensive research for a number of tumors, notably
5006: 2398:"Proceedings of the Annual Symposium on Regenerative Medicine(PASRM)" 1707: 1690: 1327: 975:
was synthetically lethal with deficient expression of the DNA repair
927: 576: 544: 498: 473: 436: 93: 2344:
Godwin P, Baird AM, Heavey S, Barr MP, O'Byrne KJ, Gately K (2013).
1937:"Simply shining light on dinosaur metal compound kills cancer cells" 1902: 887:
repair) are synthetically lethal with inhibition of DNA repair gene
3780:. Aethlonmedical.investorroom.com. 9 September 2010. Archived from 1004:
promoters (39.4 months survival) than for those with unmethylated
915: 905: 889: 879: 873: 818: 570: 525:
and, after being irradiated with light, destroy the cancer cells.
259:. Occasionally, surgery is necessary to control symptoms, such as 1587:
Fukumura D, Kloepper J, Amoozgar Z, Duda DG, Jain RK (May 2018).
1033:(American Cancer Society). The last a patient can get is Stage 4. 755:) that tumors need to survive and grow. Continued growth allows 971: 961: 782: 556: 243:, e.g. determining the extent of the disease and whether it has 2817:
Cormie P, Trevaskis M, Thornton-Benko E, Zopf EM (April 2020).
2641:"Flavonoids as Potential Anti-Inflammatory Molecules: A Review" 3772: 3770: 2690:
Ashcraft KA, Warner AB, Jones LW, Dewhirst MW (January 2019).
781:
have been shown to downregulate the angiogenic stimulation of
468:(Herceptin) used in breast cancer, and the anti-CD20 antibody 378: 310: 152:
are sometimes used to enhance the effects of immunotherapies.
1844:. In Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (eds.). 959:
gene appear to be synthetically lethal with inactivation of
435:
are targeted therapy drugs that are generally inhibitors of
3024:"Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies" 1689:
Mieog JS, van der Hage JA, van de Velde CJ (October 2007).
1322:
Fetal tumors are sometimes diagnosed while still in utero.
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expression), and 43 patients had tumors with unmethylated
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is infeasible because of its high radiation dose. Still,
456:
is another strategy in which the therapeutic agent is an
4818:"Understanding What Cancer Is: Ancient Times to Present" 3923:
National Center for Complementary and Integrative Health
2944:
Shaheen M, Allen C, Nickoloff JA, Hromas R (June 2011).
4091:"Krebstherapie in der Schwangerschaft extrem schwierig" 673:
The cell based immunotherapy in which the patients own
199:
Malignant tumours can be cured if entirely removed by
27:
Overview of various treatment possibilities for cancer
1691:"Neoadjuvant chemotherapy for operable breast cancer" 3857:"Complementary and Alternative Therapies for Cancer" 155:
The choice of therapy depends upon the location and
215:Examples of surgical procedures for cancer include 66: 54: 34: 4474:Robb KA, Simon AE, Miles A, Wardle J (July 2014). 4765:Sihvola S, Kuosmanen L, Kvist T (February 2022). 4264:Couto RA (2012). Ludke RL, Obermiller PJ (eds.). 3577:"Gold Standard Framework - Advance Care Planning" 3487:Odynets T, Briskin Y, Todorova V (January 2019). 2537:"Cancer immunologists scoop medicine Nobel prize" 2461:Journal of Stem Cells & Regenerative Medicine 1012:gene promoter is hypermethylated in about 38% of 1816:"Chemotherapy: MedlinePlus Medical Encyclopedia" 1432:List of unproven and disproven cancer treatments 535:splice switching oligonucleotides, which induce 408:requires the use of high-dose chemotherapy, and 4601:"Identity threat and stigma in cancer patients" 2402:Journal of Stem Cells and Regenerative Medicine 1963:Zhang, Pingyu, et al. (15 December 2018). 1847:Cancer Management: A Multidisciplinary Approach 1306:cannot be used, since they cross the placenta. 751:prevent the extensive growth of blood vessels ( 3314:JNCI: Journal of the National Cancer Institute 1637:"Biomarker Testing for Cancer Treatment - NCI" 3175: 3173: 1294:Diagnosis is also made more difficult, since 1037:not only to the colon but to the lymph nodes. 8: 4599:Knapp S, Marziliano A, Moyer A (July 2014). 2535:Ledford H, Else H, Warren M (October 2018). 904:Ovarian cancers have a mutational defect in 2608: 2606: 953:In colon cancer, epigenetic defects in the 698:cytotoxic T-lymphocyte associated protein 4 3714:|...|intentional=yes}} 1556: 1554: 40: 4782: 4624: 4548: 4499: 4085: 4083: 4081: 4079: 4077: 4075: 4055: 4025: 4023: 3987: 3830: 3820: 3626: 3520: 3463: 3390: 3341: 3153: 3143: 3113: 3111: 3109: 3055: 2961: 2834: 2715: 2666: 2656: 2560: 2511: 2423: 2413: 2371: 2361: 2320: 2221: 2172: 2080: 2031: 1990: 1842:"Principles of Oncologic Pharmacotherapy" 1788:"Sore mouth and problems with your teeth" 1763: 1738:Baskar R, Lee KA, Yeo R, Yeoh KW (2012). 1706: 1612: 1476: 1474: 1472: 575:A renal cell carcinoma (lower left) in a 4996:) is being considered for deletion. See 3855:Cassileth BR, Deng G (1 February 2004). 2486:Buchbinder EI, Desai A (February 2016). 2202:Signal Transduction and Targeted Therapy 1442:Timeline of cancer treatment development 1117:movement, a more recent offshoot of the 1058:chemotherapy-induced nausea and vomiting 203:. But if the cancer has already spread ( 3542: 3540: 2692:"Exercise as Adjunct Therapy in Cancer" 1879:(CRC, New York, 2009) Chapters 5, 7, 8. 1810: 1808: 1468: 660:hematopoietic stem cell transplantation 4299:African Journal of Reproductive Health 4221: 4219: 4217: 3571: 3569: 3206:"Managing and treating cancer fatigue" 2868:Australian Journal of General Practice 2823:Australian Journal of General Practice 1254:Complementary and alternative medicine 1008:promoters (20.7 months survival). The 563:in models of chemotherapy resistance. 397:and vomiting depending on the person. 31: 4442: 4440: 4388: 4386: 4259: 4257: 4114: 4112: 2492:American Journal of Clinical Oncology 684:autologous immune enhancement therapy 7: 4909:European Journal of Oncology Nursing 4650:Journal of Applied Social Psychology 4574:Journal of Applied Social Psychology 3083:. U.S. Food and Drug Administration. 501:). PDT can be used as treatment for 309:and shrink tumors by damaging their 251:. Staging is a major determinant of 3976:CA: A Cancer Journal for Clinicians 1507:"Targeted Therapy for Cancer - NCI" 1042:Symptom control and palliative care 590:Bladder cancer Β§ Immunotherapy 75: 3436:Journal of Clinical Sleep Medicine 2819:"Exercise medicine in cancer care" 2585:"Hormone Therapy for Cancer - NCI" 899:microhomology-mediated end joining 851:epigenetic silencing of DNA repair 381:or the separation of newly formed 25: 5000:to help reach a consensus. β€Ί 4869:Psychology, Health & Medicine 4266:Appalachian Health and Well-Being 3809:Journal of Translational Medicine 3581:www.goldstandardsframework.org.uk 3094:Commissioner Oo (18 March 2019). 1562:"Types of Cancer Treatment - NCI" 649:from the patient are loaded with 4662:10.1111/j.1559-1816.2012.00945.x 4586:10.1111/j.1559-1816.2009.00550.x 4353:10.1097/00005650-198910000-00005 4268:. University Press of Kentucky. 4240:10.1097/00005650-199609000-00008 3232:Patient Education and Counseling 617:to induce an immune response in 365:is the treatment of cancer with 2708:10.1016/j.semradonc.2018.10.001 2614:"Angiogenesis Inhibitors - NCI" 914:and 5% somatic mutations) (see 847:DNA repair deficiency in cancer 759:into neighbouring tissues, and 702:programmed cell death protein 1 641:is a vaccine-like strategy for 163:of the disease, as well as the 3845:DOI: 10.1038/s41392-020-0205-z 3371:Nature Reviews Disease Primers 2696:Seminars in Radiation Oncology 2408:(1): 40–56. 26 December 2006. 1695:The British Journal of Surgery 926:, was approved in 2014 by the 910:in about 18% of patients (13% 871:Mutations in DNA repair genes 605:immunotherapy for superficial 551:with other pathways including 343:Radiation therapy can lead to 173:experimental cancer treatments 1: 3279:10.1016/S0140-6736(03)13310-7 3244:10.1016/S0738-3991(99)00108-1 3000:10.1016/S1470-2045(14)70228-1 2266:10.1016/j.lungcan.2019.07.006 2033:10.1016/j.jconrel.2015.05.265 2020:Journal of Controlled Release 1850:(11 ed.). Archived from 1840:Takimoto CH, Calvo E (2008). 1532:Research Cf (11 March 2022). 1417:Experimental cancer treatment 1339:Racial and social disparities 1249:Alternative cancer treatments 1243:Complementary and alternative 1192:Experimental cancer treatment 1048:Cancer pain Β§ Management 301:(radiotherapy) is the use of 4881:10.1080/13548506.2012.686619 4133:10.1097/MLR.0b013e3181a393fe 3941:Journal of Clinical Oncology 3925:. Retrieved 3 February 2008. 3876:10.1634/theoncologist.9-1-80 3493:Integrative Cancer Therapies 2963:10.1182/blood-2011-01-313734 2911:Journal of Clinical Oncology 2504:10.1097/COC.0000000000000239 2301:Cancer Biology & Therapy 1676:10.1016/j.eursup.2012.04.002 1664:European Urology Supplements 1151:Cognitive behavioral therapy 789:(HIF) but none have reached 547:inhibitors that inhibit the 4693:10.1016/j.ypmed.2021.106849 4492:10.1136/bmjopen-2014-005434 4395:Cancer Causes & Control 4172:Cancer Causes & Control 3953:10.1200/JCO.2000.18.13.2505 3683:10.1016/j.ygyno.2023.06.002 3664:10.1016/j.ygyno.2008.04.033 3619:10.1136/bmj.38628.561123.7C 718:Hormonal therapy (oncology) 454:Monoclonal antibody therapy 5048: 4921:10.1016/j.ejon.2017.06.001 4844:10.1007/s00520-019-04685-5 4784:10.1016/j.ejon.2021.102079 4736:10.1016/j.ejon.2023.102453 4541:10.1016/j.jtho.2018.05.014 4048:10.1007/s00261-023-03809-0 3935:Richardson MA, Sanders T, 3079:Yao S (19 December 2014). 2562:10.1038/d41586-018-06751-0 2126:10.1016/j.ctrv.2013.08.006 1877:Tunable Laser Applications 1300:magnetic resonance imaging 1246: 1189: 1182:with relatives or carers. 1090:and analogues, as well as 1045: 946: 885:homologous recombinational 864: 831: 800: 741: 715: 651:prostatic acid phosphatase 637:and renal cell carcinoma. 587: 581: 441:tyrosine kinase inhibitors 423: 355: 323:external beam radiotherapy 291: 285: 132:. Other therapies include 4832:Supportive Care in Cancer 4407:10.1007/s10552-004-1253-3 4184:10.1007/s10552-004-1263-1 3998:10.3322/canjclin.54.2.110 2658:10.3390/molecules27092901 2214:10.1038/s41392-020-0109-y 2165:10.18632/oncotarget.12755 2073:10.1038/s41416-020-0951-2 2061:British Journal of Cancer 1605:10.1038/nrclinonc.2018.29 1447:Multimodal cancer therapy 1359:National Cancer Institute 1302:works normally. However, 1123:World Health Organization 901:pathways of DNA repair). 690:Immune checkpoint therapy 668:graft-versus-tumor effect 414:stem cell transplantation 267:. This is referred to as 227:for prostate cancer, and 76: 39: 4998:templates for discussion 4617:10.1177/2055102914552281 4461:10.1525/sp.2005.52.2.255 3505:10.1177/1534735419880598 3210:www.cancerresearchuk.org 2923:10.1200/JCO.2005.05.4171 2880:10.31128/AJGP-10-19-5110 2836:10.31128/AJGP-08-19-5027 2741:Comprehensive Physiology 2114:Cancer Treatment Reviews 1792:www.cancerresearchuk.org 1427:List of cancer hospitals 787:Hypoxia-inducible factor 519:photosensitized molecule 4611:(1): 2055102914552281. 3145:10.1073/pnas.0600645103 2363:10.3389/fonc.2013.00120 1452:War metaphors in cancer 1402:American Cancer Society 1350:Veterans Administration 749:Angiogenesis inhibitors 738:Angiogenesis inhibitors 482:can also involve small 472:, used in a variety of 261:spinal cord compression 150:Angiogenesis inhibitors 46:A patient prepared for 4950:10.1188/12.ONF.500-506 4938:Oncology Nursing Forum 3822:10.1186/1479-5876-6-37 3753:10.3816/CLC.2009.n.006 1983:10.1002/anie.201813002 1891:Nature Reviews. Cancer 1129:Cancer-related fatigue 824: 810:Exercise physiologists 744:Angiogenesis inhibitor 706:tumor microenvironment 579: 543:models, multitargeted 410:total body irradiation 400:The treatment of some 3726:16 April 2016 at the 3706:|...}} 3677:(Retracted, see 3028:Nature Communications 2796:10.1093/epirev/mxx007 2784:Epidemiologic Reviews 2415:10.46582/jsrm.0101007 2350:Frontiers in Oncology 1933:University of Warwick 1264:Special circumstances 1135:Mental struggles/pain 1046:Further information: 822: 803:Exercise prescription 797:Exercise prescription 757:the invasion of cells 629:to generate specific 588:Further information: 574: 446:(Gleevec/Glivec) and 159:of the tumor and the 122:monoclonal antibodies 3741:Clinical Lung Cancer 3652:Gynecologic Oncology 3383:10.1038/nrdp.2015.26 2988:The Lancet. Oncology 2753:10.1002/cphy.c180016 1388:human papillomavirus 1284:may be recommended. 1282:therapeutic abortion 1258:alternative medicine 1230:13 July 2011 at the 895:base excision repair 675:natural killer cells 619:renal cell carcinoma 595:Cancer immunotherapy 584:Cancer immunotherapy 559:, and inhibitors of 503:basal cell carcinoma 495:Photodynamic therapy 488:extracellular matrix 433:Small molecule drugs 269:palliative treatment 255:and of the need for 142:photodynamic therapy 118:small-molecule drugs 4605:Health Psychol Open 4335:, Yergan J, Chu J, 3499:: 153473541988059. 3367:"Insomnia disorder" 3326:10.1093/jnci/djz050 3273:(9369): 1603–1607. 3136:2006PNAS..103.8822A 3048:10.1038/ncomms12425 3040:2016NatCo...712425D 2553:2018Natur.562...20L 2159:(48): 79526–79543. 1935:(3 February 2019). 1334:Society and culture 1296:computed tomography 855:DNA repair pathways 839:Synthetic lethality 834:Synthetic lethality 828:Synthetic lethality 662:(usually from the 229:lung cancer surgery 223:for breast cancer, 186:Types of treatments 18:Treatment of cancer 5027:Medical treatments 3392:20.500.11794/67139 1593:Nat Rev Clin Oncol 1437:Precision medicine 1162:cancer survivors. 1014:colorectal cancers 912:germline mutations 825: 635:malignant melanoma 580: 420:Targeted therapies 325:or internally via 303:ionizing radiation 5022:Cancer treatments 4838:(10): 3785–3792. 4656:(10): 2368–2385. 4580:(12): 2798–2808. 4036:Abdom Radiol (NY) 3784:on 11 August 2011 3448:10.5664/jcsm.7586 3320:(12): 1323–1331. 2313:10.4161/cbt.29841 2307:(10): 1367–1377. 1970:Angewandte Chemie 1854:on 4 October 2013 1756:10.7150/ijms.3635 1412:Cancer prevention 1407:Cancer and nausea 1378:Public perception 1348:findings. The US 965:. In particular, 949:Colorectal cancer 814:exercise medicine 694:immune checkpoint 679:cytotoxic T cells 539:exon skipping in 299:Radiation therapy 288:Radiation therapy 282:Radiation therapy 265:bowel obstruction 169:Biomarker testing 146:stem-cell therapy 106:radiation therapy 90:Cancer treatments 87: 86: 48:radiation therapy 16:(Redirected from 5039: 5003:Cancer Treatment 4969: 4932: 4900: 4863: 4825: 4805: 4804: 4786: 4771:Eur J Oncol Nurs 4762: 4756: 4755: 4724:Eur J Oncol Nurs 4719: 4713: 4712: 4672: 4666: 4665: 4645: 4639: 4638: 4628: 4596: 4590: 4589: 4569: 4563: 4562: 4552: 4535:(8): 1062–1075. 4520: 4514: 4513: 4503: 4471: 4465: 4464: 4444: 4435: 4434: 4390: 4381: 4380: 4329: 4323: 4322: 4294: 4288: 4287: 4261: 4252: 4251: 4223: 4212: 4211: 4167: 4161: 4160: 4116: 4107: 4106: 4104: 4102: 4087: 4070: 4069: 4059: 4042:(5): 1605–1611. 4027: 4018: 4017: 3991: 3971: 3965: 3964: 3932: 3926: 3917: 3911: 3910: 3908: 3906: 3900: 3894:. 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32: 21: 5047: 5046: 5042: 5041: 5040: 5038: 5037: 5036: 5012: 5011: 5001: 4982: 4935: 4906: 4866: 4828: 4816: 4813: 4808: 4764: 4763: 4759: 4721: 4720: 4716: 4674: 4673: 4669: 4647: 4646: 4642: 4598: 4597: 4593: 4571: 4570: 4566: 4522: 4521: 4517: 4473: 4472: 4468: 4449:Social Problems 4446: 4445: 4438: 4392: 4391: 4384: 4347:(10): 942–958. 4331: 4330: 4326: 4296: 4295: 4291: 4276: 4263: 4262: 4255: 4225: 4224: 4215: 4169: 4168: 4164: 4118: 4117: 4110: 4100: 4098: 4097:on 6 March 2016 4089: 4088: 4073: 4029: 4028: 4021: 3989:10.1.1.521.2180 3973: 3972: 3968: 3947:(13): 2505–14. 3934: 3933: 3929: 3918: 3914: 3904: 3902: 3901:on 19 July 2018 3898: 3859: 3854: 3853: 3849: 3802: 3801: 3797: 3787: 3785: 3776: 3775: 3768: 3738: 3737: 3733: 3728:Wayback Machine 3709: 3701: 3699: 3676: 3649: 3648: 3644: 3600: 3599: 3595: 3585: 3583: 3575: 3574: 3567: 3557: 3555: 3546: 3545: 3538: 3486: 3485: 3481: 3429: 3428: 3424: 3364: 3363: 3359: 3307: 3306: 3302: 3264: 3263: 3259: 3229: 3228: 3224: 3214: 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4515: 4486:(7): e005434. 4466: 4455:(2): 255–271. 4436: 4382: 4324: 4305:(3): 195–200. 4289: 4274: 4253: 4234:(9): 970–984. 4213: 4162: 4127:(7): 774–781. 4108: 4071: 4019: 3966: 3927: 3912: 3864:The Oncologist 3847: 3795: 3766: 3731: 3642: 3613:(7528): 1295. 3593: 3565: 3554:. 27 July 2023 3548:"Hospice care" 3536: 3479: 3442:(1): 129–137. 3422: 3357: 3300: 3257: 3238:(2): 145–156. 3222: 3197: 3185:www.cancer.org 3169: 3130:(23): 8822–7. 3105: 3086: 3071: 3013: 2977: 2936: 2901: 2874:(4): 182–186. 2858: 2829:(4): 169–174. 2809: 2774: 2747:(1): 165–205. 2731: 2682: 2631: 2618:www.cancer.gov 2602: 2589:www.cancer.gov 2576: 2527: 2478: 2447: 2387: 2336: 2287: 2237: 2188: 2139: 2120:(3): 445–456. 2104: 2047: 2006: 1955: 1924: 1881: 1865: 1832: 1804: 1779: 1730: 1681: 1654: 1641:www.cancer.gov 1628: 1599:(5): 325–340. 1579: 1568:. 31 July 2017 1566:www.cancer.gov 1550: 1524: 1511:www.cancer.gov 1498: 1467: 1465: 1462: 1460: 1459: 1454: 1449: 1444: 1439: 1434: 1429: 1424: 1419: 1414: 1409: 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564: 562: 558: 554: 550: 546: 542: 538: 534: 529: 526: 524: 520: 517:, creating a 516: 512: 508: 504: 500: 496: 492: 489: 485: 481: 477: 475: 471: 467: 463: 459: 455: 451: 449: 445: 442: 438: 434: 427: 419: 417: 415: 411: 407: 403: 398: 394: 390: 388: 384: 380: 376: 372: 368: 364: 359: 351: 349: 346: 341: 339: 335: 330: 328: 327:brachytherapy 324: 320: 319:free radicals 316: 312: 308: 304: 300: 295: 289: 281: 279: 277: 272: 270: 266: 262: 258: 254: 250: 246: 242: 237: 235: 230: 226: 225:prostatectomy 222: 218: 213: 210: 206: 202: 194: 192: 185: 183: 181: 176: 174: 170: 166: 165:general state 162: 158: 153: 151: 147: 143: 139: 138:immunotherapy 135: 131: 127: 123: 119: 115: 111: 107: 103: 99: 95: 91: 81: 71: 69: 65: 62: 59: 57: 53: 49: 43: 38: 33: 30: 19: 4991: 4941: 4937: 4912: 4908: 4875:(1): 10–20. 4872: 4868: 4835: 4831: 4821: 4811:Bibliography 4774: 4770: 4760: 4727: 4723: 4717: 4684: 4680: 4670: 4653: 4649: 4643: 4608: 4604: 4594: 4577: 4573: 4567: 4532: 4528: 4518: 4483: 4479: 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Retrieved 4095:the original 4039: 4035: 3982:(2): 110–8. 3979: 3975: 3969: 3944: 3940: 3930: 3920:What Is CAM? 3915: 3903:. Retrieved 3896:the original 3870:(1): 80–89. 3867: 3863: 3850: 3812: 3808: 3798: 3786:. Retrieved 3782:the original 3744: 3740: 3734: 3710:{{ 3702:{{ 3695: 3693:,   3658:(1): 13–21. 3655: 3651: 3645: 3610: 3606: 3596: 3584:. Retrieved 3580: 3556:. Retrieved 3551: 3496: 3492: 3482: 3439: 3435: 3425: 3377:(1): 15026. 3374: 3370: 3360: 3317: 3313: 3303: 3270: 3266: 3260: 3235: 3231: 3225: 3213:. Retrieved 3209: 3200: 3188:. Retrieved 3184: 3127: 3123: 3099: 3089: 3074: 3031: 3027: 3016: 2991: 2987: 2980: 2953: 2949: 2939: 2914: 2910: 2904: 2871: 2867: 2861: 2826: 2822: 2812: 2790:(1): 71–92. 2787: 2783: 2777: 2744: 2740: 2734: 2702:(1): 16–24. 2699: 2695: 2685: 2648: 2644: 2634: 2622:. Retrieved 2620:. 1 May 2018 2617: 2593:. 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Index

Treatment of cancer

radiation therapy
Specialty
Oncology
ICD-10-PCS
edit on Wikidata
cancer
surgery
chemotherapy
radiation therapy
hormonal therapy
targeted therapy
small-molecule drugs
monoclonal antibodies
PARP inhibitors
olaparib
hyperthermia
immunotherapy
photodynamic therapy
stem-cell therapy
Angiogenesis inhibitors
grade
stage
general state
Biomarker testing
experimental cancer treatments
Palliative care
surgery
metastasized

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

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