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Treatment of mental disorders

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by the US Food and Drug Administration for adjunctive treatment of MDD in adults with inadequate response to antidepressant therapy in the current episode. Recommended doses of aripiprazole range from 2 mg/d to 15 mg/d based on 2 large, multicenter randomized, double-blind, placebo-controlled studies, which were later supported by a third large trial. Most conventional antipsychotics, such as the phenothiazines, work by blocking the D2 Dopamine receptors. Atypical antipsychotics, such as clozapine block both the D2 Dopamine receptors as well as 5HT2A serotonin receptors. Atypical antipsychotics are favored over conventional antipsychotics because they reduce the prevalence of pseudoparkinsonism which causes tremors and muscular rigidity similar to Parkinson's disease. The most severe side effect of antipsychotics is agranulocytosis, a depression of white blood cell count with unknown cause, and some patients may also experience photosensitivity. Atypical and conventional antipsychotics also differ in the fact that atypical medications help with both positive and negative symptoms while conventional medications only help with the positive symptoms; negative symptoms being things that are taken away from the person such as a reduction in motivation, while positive symptoms are things being added such as seeing illusions.
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beneficial short-term effect at lower intensities. Demonstrating that lower intensity sessions with longer rest periods produced significantly higher positive affect and reduced anxiety when measured shortly after. Physical activity was found to be beneficial regardless of age and gender. Some studies found exercise to be more effective at treating depression than medication over long periods of time, but the most effective treatment of depression was exercise in combination with antidepressants. Exercise appeared to have the greatest effect on mental health a short period of time after exercise. Different studies have found this time to be from twenty minutes to several hours. Patients who have added exercise to other treatments tend to have more consistent long lasting relief from symptoms than those who just take medication. No single regimented workout has been agreed upon as most effective for any mental illness at this time. The exercise programs prescribed are mostly intended to get patients doing some form of physical activity, as the benefits of doing any form of exercise have been proven to be better than doing nothing at all.
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when a small hole was drilled into a person's skull to let out demons, as that was an earlier belief for mental disorders. Bloodletting is when a certain amount of blood was drained out of a person, due to the belief that chemical imbalances resulted in mental disorders. A more scientific reason behind mental disorders but both treatments were dangerous and ineffective nevertheless. During the 17th century however, many people with mental disorders were just locked away in institutions due to lack of knowledgeable treatment. Mental institutions became the main treatment for a long period of time. But though years of research, studies, and medical developments, many current treatments are now effective and safe for patients. Early glimpses of treatment of mental illness included dunking in cold water by Samuel Willard (physician), who reportedly established the first American hospital for mental illness. The history of treatment of mental disorders consists in a development through years mainly in both
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completing studies, which were often highly problematic due to problems such as getting patients to complete their trials, controlling for all possible variables, and finding adequate ways to test progress. Data were often collected through case and population studies, allowing for less control, but still gathering observations. More recently studies have begun to have more established methods in an attempt to start to comprehend the benefits of different levels and amounts of fitness across multiple age groups, genders, and mental illnesses. Some psychologists are recommending fitness to patients, however the majority of doctors are not prescribing patients with a full program.
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which can lead to a hypertensive crisis. Research on improving phenothiazine antipsychotics led to the development of tricyclic antidepressants which inhibit synaptic uptake of the neurotransmitters norepinephrine and serotonin. SSRIs or selective serotonin reuptake inhibitors are the most frequently used antidepressant. These drugs share many similarities with the tricyclic antidepressants but are more selective in their action. The greatest risk of the SSRIs is an increase in violent and suicidal behavior, particularly in children and adolescents. In 2006 antidepressant sales worldwide totaled US$ 15 billion and over 226 million prescriptions were given.
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interest in the state asylums. He trained at the Parisian Asylum. Parkman wrote several papers on treatment for the mentally ill. Oliver Wendell Holmes Sr.(1809–1894) was an American Physician who wrote many famous writings on medical treatments. George Zeller (1858–1938) was famous for his way of treating the mentally ill. He believed they should be treated like people and did so in a caring manner. He banned narcotics, mechanical restraints, and imprisonment while he was in charge at Peoria State Asylum. Peter Breggin (1939–present) disagrees with the practices of harsh psychiatry such as electroconvulsive therapy. 
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found that research participants who expressed shame from personal experiences with mental illnesses were less likely to participate in treatment. Additionally, family shame is also a predictor of avoiding treatment. Research showed that people with psychiatric diagnoses were more likely to avoid services if they believed family members would have a negative reaction to said services. Hence, public stigma can influence self-stigma, which has been shown to decrease treatment involvement. As such, the interaction between the two constructs impact care seeking.
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patients just needed time away from the stresses of modern life. Which he believed was the cause of mental disorders to develop. Benjamin Rush(1746–1813) was considered the Father of American Psychiatry for his many works and studies in the mental health field. He tried to classify different types of mental disorders, he theorized about their causes, and tried to find possible cures for them. Rush believed that mental disorders were caused by poor blood circulation, though he was wrong. He also described Savant Syndrome and had an approach to addictions.
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along with other negative effects of stigmatization have led researchers to conduct studies on the relationship between public stigma and care seeking. Researchers have found that an inverse relationship exists between public stigma and care seeking, as well as between stigmatizing attitudes and treatment adherence. Furthermore, specific beliefs that may influence people not to seek treatment have been identified, one of which is concern over what others might think.
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framework for classifying other disorders. However this method of research/work was ignored until the need for a universal classification system. This need would later lead to the creation of the DSM. Which not only provided classification of mental disorders but helped to understand where to start in terms of treatment.
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In addition of atypical antipsychotics in cases of inadequate response to antidepressant therapy is an increasingly popular strategy that is well supported in the literature, though these medications may result in greater discontinuation due to adverse events. Aripiprazole was the first drug approved
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Treatments, as well as societies attitudes towards mental illnesses have substantially changed throughout the years. Many earlier treatments for mental illness were later deemed as ineffective as well dangerous. Some of these earlier treatments included trephination and bloodletting. Trephination was
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are classified as a psychological condition marked primarily by sufficient disorganization of personality, mind, and emotions to seriously impair the normal psychological and often social functioning of the individual. Individuals diagnosed with certain mental disorders can be unable to function
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Early antidepressants were discovered through research on treating tuberculosis and yielded the class of antidepressants known as monoamine oxidase inhibitors (MAO). Only two MAO inhibitors remain on the market in the United States because they alter the metabolism of the dietary amino acid tyramine
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Laurence J. Kirmayer, in "Cultural Variations in the Clinical Presentation of Depression and Anxiety" (2001), expands on Kleinman's critique by demonstrating that mental health conditions manifest differently across cultures. Kirmayer advocates for culturally sensitive treatment approaches that not
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Electroconvulsive therapy (known as ECT) is when electric currents are applied to someone with a mental disorder who is not responding well to other forms of therapy. Psychosurgery, including deep brain stimulation, is another available treatment for some disorders. This form of therapy is disputed
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Beside psychotherapy, a wide range of medication is used in the treatment of mental disorders. The first drugs used for this purpose were extracted from plants with psychoactive properties. Louis Lewin, in 1924, was the first one to introduce a classification of drugs and plants that had properties
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The internalization of stigmas may lead to self-prejudice which in turn can lead a person to experience negative emotional reactions, interfering with a person's quality of life. Research has shown a significant relationship between shame and avoiding treatment. A study measuring this relationship
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Public stigmas may also harm social opportunities. Prejudice frequently disallows people with mental illnesses from finding suitable housing or procuring good jobs. Studies have shown that stereotypes and prejudice about mental illness have harmful impacts on obtaining and keeping good jobs. This,
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is also widely used to treat mental disorders. These are licensed psychoactive drugs usually prescribed by a psychiatrist or family doctor. There are several main groups. Antidepressants are used for the treatment of clinical depression as well as often for anxiety and other disorders. Anxiolytics
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Different perspectives on the causes of psychological disorders arose. Some believed that stated that psychological disorders are caused by specific abnormalities of the brain and nervous system and that is, in principle, they should be approached for treatments in the same way as physical illness
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Public discourse on mental health treatment often centers on the biomedical model, which primarily treats mental illness with medication. While widespread, this approach can reinforce stigma by oversimplifying the complexity of mental health conditions. Arthur Kleinman, in "Rethinking Psychiatry"
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Other important early psychiatrists include George Parkman, Oliver Wendell Holmes Sr., George Zeller, Carl Jung, Leo Kanner, and Peter Breggin. George Parkman (1790–1849) got his medical degree at the University of Aberdeen in Scotland. He was influenced by Benjamin Rush, who inspired him to take
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There are numbers of practitioners who have influenced the treatment of modern mental disorders. During the 18th century in Philippe Pinel a French physician helped/advocated for better treatment of patients with mental disorders. Similar to Pinel Benjamin Rush, a Philadelphian physician believed
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72.Kleinman, Arthur. (1988). Rethinking Psychiatry: From Cultural Category to Personal Experience. Free Press. 73.Kirmayer, Laurence J. (2001). "Cultural Variations in the Clinical Presentation of Depression and Anxiety: Implications for Diagnosis and Treatment." Journal of Clinical Psychiatry,
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In America, half of people with severe symptoms of a mental health condition were found to have received no treatment in the prior 12 months. Fear of disclosure, rejection by friends, and ultimately discrimination are a few reasons why people with mental health conditions often don't seek help.
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normally in society. Mental disorders may consist of several affective, behavioral, cognitive and perceptual components. The acknowledgement and understanding of mental health conditions has changed over time and across cultures. There are still variations in the definition, classification, and
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Anthropologist Byron J. Good, in "Medicine, Rationality, and Experience"(1994), further supports these views by arguing that mental health treatment must consider cultural narratives that shape individuals' experiences. Together, these scholars advocate for a shift from the limitations of the
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Many early studies show that physical activity has positive effects on subjects with mental illness. Most studies have shown that higher levels of exercise correlate to improvement in mental state, especially for depression. On the other hand, some studies have found that exercise can have a
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German Physician Emil Kraepelin was more interested in the causes of mental disorders and potential classifications rather than focusing on and attempting to treating symptoms of mental disorders. This led to the classification of manic depression and Schizophrenia, as well as the start of a
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is a more recent therapy that was  founded in the 1960s by Aaron T. Beck, an American psychiatrist. It is a more systematic and structured part of psychotherapy. It consist in helping the patient learn effective ways to overcome their problems and difficulties that causes them distress.
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has become apparent, research on the mental benefits of physical activity has been examined. While it was originally believed that physical activity only slightly benefits mood and mental state, overtime positive mental effects from physical activity became more pronounced. Scientists began
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The stigmatization of mental illnesses can elicit stereotypes, some common ones including violence, incompetence, and blame. However, the manifestation of that stereotype into prejudice may not always occur. When it does, prejudice leads to discrimination, the behavioral reaction.
291:. Mental health professionals often pick and choose techniques, employing an eclectic or integrative approach tailored to a particular disorder and individual. Much may depend on the therapeutic relationship, and there may be issues of trust, confidentiality and engagement. 191:
Psychotherapy is a relatively new method used in treatment of mental disorders. The practice of individual psychotherapy as a treatment of mental disorders is about 100 years old. Sigmund Freud (1856–1939) was the first one to introduce this concept in psychoanalysis.
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To regulate the potentially powerful influences of therapies, psychologists hold themselves to a set of ethical standers for the treatment of people with mental disorders, written by the American Psychological Association. These ethical standards include:
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Despite the different conventional names of the drug groups, there can be considerable overlap in the kinds of disorders for which they are actually indicated. There may also be off-label use. There can be problems with adverse effects and adherence.
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in 1934. He induced seizures through a series of injections, as a means to attempt to treat schizophrenia.  Meanwhile, in Italy, Ugo Cerletti  substituted injections with electricity. Because of this substitution the new theory was called
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only improve diagnosis but also reduce stigma by recognizing cultural differences. This work counters the misconception that mental illness is a universal experience, instead promoting a nuanced approach that considers cultural context.
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and perceived stigma. Though separated into different categories, the two can interact with each other, where prejudicial attitudes in social stigma lead to the internalization of discriminatory perceptions in perceived stigma.
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are used, generally short-term, for anxiety disorders and related problems such as physical symptoms and insomnia. Mood stabilizers are used primarily in bipolar disorder, mainly targeting mania rather than depression.
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Sirey J. A.; Bruce M. L.; Alexopoulos G. S.; Perlick D. A.; Raue P.; Friedman S. J.; Meyers B. S. (2001). "Perceived stigma as a predictor of treatment discontinuation in young and older outpatients with depression".
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Creative therapies are sometimes used, including music therapy, art therapy or drama therapy. Each form of these therapy involves performing, creating, listening to, observing, or being a part of the therapeutic act.
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The benefactors of the Medical School of Harvard University : with a biographical sketch of the late Dr. George Parkman: an introductory lecture, delivered at the Massachusetts Medical College, November 7,
217:, was discovered as a treatment of mania, by John F. Cade in 1949, "and Hammond (1871) used lithium bromide for 'acute mania with depression'". In 1937, Daniel Bovet and Anne-Marie Staub discovered the first 267:(CBT) is used for a wide variety of disorders, based on modifying the patterns of thought and behavior associated with a particular disorder. There are various kinds of CBT therapy, and offshoots such as 401:
Lifestyle adjustments and supportive measures are often used, including peer support, self-help and supported housing or employment. Some advocate dietary supplements. A placebo effect may play a role.
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Mental health services may be based in hospitals, clinics or the community. Often an individual may engage in different treatment modalities and use various mental health services. These may be under
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62(suppl 13), 22–28. 74.Scheper-Hughes, Nancy, & Lock, Margaret M. (1987). "The Mindful Body: A Prolegomenon to Future Work in Medical Anthropology." Medical Anthropology Quarterly, 1(1), 6-41.
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of this kind. The history of the medications used in mental disorders has developed a lot through years. The discovery of modern drugs prevailed during the 20th century. Lithium, a
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David Mischoulon; Janet Witte; Michael Levy; George I. Papakostas; L. Russell Pet; Wen-hua Hsieh; Michael J. Pencina; Sean Ward; Mark H. Pollack; Maurizio Fava (2011-10-02).
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program. Providing optimal treatments earlier in the course of a mental health disorder may prevent further relapses and ongoing disability. This has led to a new
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Music therapy may provide a means of improving mental health among people with schizophrenia, but its effects in acute psychoses have not been explored
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Dunn, Andrea L.; Trivedi, Madhukar H.; Kampert, James B.; Clark, Camillia G.; Chambliss, Heather O. (2005-01-01). "Exercise treatment for depression".
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Digital Treasures, Samuel Willard ran a "hospital for the insane" l and trained young physicians, East side of Uxbridge Common, (no longer standing)
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Behavior therapy has its roots in experimental psychology. E.L. Thorndike and B.F. Skinner were among the first to work on behavior therapy.
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such as a clinical psychologist, that employs any of a range of specific psychological techniques. There are several main types.
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is sometimes used, addressing a network of relationships as well as individuals themselves. Some psychotherapies are based on a
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The Modern Treatment of Mental and Nervous Disorders: a lecture delivered at the University of Manchester, on 25th March 1918
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biomedical model toward a more holistic and culturally informed approach, crucial for reducing stigma and improving care.
429: 411: 372: 65: 1220: 275:, addressing underlying psychic conflicts and defenses, has been a dominant school of psychotherapy and is still in use. 1590:"Maintenance therapy with second generation antipsychotics for bipolar disorder – A systematic review and meta-analysis" 609: 268: 264: 193: 1855: 2968: 1521: 624: 2711:
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The UK is moving towards paying mental health providers by the outcome results that their services achieve.
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can lead people with mental health conditions not to seek help. Two types of mental health stigmas include
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in smaller doses to treat anxiety. Stimulants are commonly used, notably for ADHD.
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approach. Some therapies are for a specific disorder only, for example
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Seeking fairness in treatment and taking precautions to avoid biases;
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service approach for psychosis Some approaches are based on a
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Research on the effects of physical activity on mental illness
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Striving to benefit clients and taking care to do no harm;
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Key concepts in psychotherapy integration, Jerold R. Gold
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John Wiley & Sons, Inc. pp.  658:"A History of Mental Illness Treatment" 648: 289:interpersonal and social rhythm therapy 2910: 1856:"Monoamine oxidase inhibitors (MAOIs)" 1103:Neuropsychiatric Disease and Treatment 996:"The first psychiatric use of lithium" 128: 2793: 2791: 2754:Journal of Nervous and Mental Disease 2622: 2620: 2618: 2361:National Institution of Mental Health 2294: 2292: 2268: 2266: 2216: 2214: 2170: 2168: 1986: 1984: 1982: 1980: 1327: 1325: 200:Convulsive therapy was introduced by 7: 2727:Journal of Applied Social Psychology 2588:Repper, J. & Perkins, R. (2006) 1636:"List of Antipsychotics - Drugs.com" 55:adding citations to reliable sources 1659:Abuse, National Institute on Drug. 770:Psychology the Science of Behaviour 558:also known as convulsive therapies 448:and creating empowerment and hope. 145: 2766:10.1097/01.nmd.0000066157.47101.22 2739:10.1111/j.1559-1816.1986.tb01135.x 1880:"Tricyclic antidepressants (TCAs)" 1488:American Psychological Association 1041:World Allergy Organization Journal 188:(arose from Hippocrates's ideas). 184:(drugs used in mental disorders). 142:Psychiatry and clinical psychology 25: 2713:The handbook of social psychology 2566:"The Placebo Effect: What Is It?" 2430:The British Journal of Psychiatry 2227:European Journal of Public Health 2139:Reynolds, Gretchen (2016-11-16). 1991:Martinsen, Egil W. (2008-01-01). 1565:"Medication for Bipolar Disorder" 1000:The British Journal of Psychiatry 798:Mulhauser, Greg (22 April 2011). 1945:10.1016/j.drugalcdep.2008.07.018 1037:"Pharmacology of Antihistamines" 709:"DIGITAL TREASURES: Item Viewer" 31: 1244:Holmes, Oliver Wendell (1850). 464:Stigma against mental disorders 434:early intervention in psychosis 66:"Treatment of mental disorders" 42:needs additional citations for 2801:American Journal of Psychiatry 1711:Journal of Clinical Psychology 1594:Journal of Affective Disorders 1151:Social Welfare History Project 656:Creech, Jeffrey (2020-07-13). 371:As increasing evidence of the 1: 2993:Treatment of mental disorders 2357:"Brain Stimulation Therapies" 1806:Journal of Psychopharmacology 1300:10.1093/jhmas/viii.january.56 969:House, Via the (2011-03-11). 430:assertive community treatment 412:Services for mental disorders 373:benefits of physical activity 165:treatment of mental disorders 132:Treatment of mental disorders 2967:(1st ed.), Manchester: 2318:10.1519/JSC.0b013e3181ae794b 2189:10.1016/j.amepre.2004.09.003 2052:Handbook of Sport Psychology 1997:Nordic Journal of Psychiatry 1363:Indian Journal of Psychiatry 971:"Phantastica by Louis Lewin" 610:Cognitive behavioral therapy 269:dialectical behavior therapy 265:Cognitive behavioral therapy 194:Cognitive behavioral therapy 2969:Manchester University Press 2110:10.1016/j.ypmed.2005.12.002 1933:Drug and Alcohol Dependence 1219:Hanson, Dirk (2010-07-05). 994:Schou, M. (1 August 1992). 625:Interpersonal psychotherapy 428:program or take part in an 426:psychosocial rehabilitation 18:Treatment of mental illness 3014: 2813:10.1176/appi.ajp.158.3.479 2651:10.1037/0003-066X.59.7.614 2066:10.1002/9781118270011.ch21 1524:. Drugs.com. 30 March 2023 1054:10.1186/1939-4551-4-S3-S22 734:Meyer, Jerrold S. (2005). 409: 261:mental health professional 2444:10.1192/bjp.bp.105.015073 2010:10.1080/08039480802315640 1606:10.1016/j.jad.2017.02.012 1267:www.online-literature.com 767:R. Carlson, Neil (2010). 681:Lincoln, William (1862). 568:Electroconvulsive therapy 424:. Patients can utilize a 207:electroconvulsive therapy 146: 2840:Health Services Research 1818:10.1177/0269881107088441 1460:"What is Psychotherapy?" 892:www.simplypsychology.org 2592:Bailliere Tindall, UK. 2494:"What is Drama Therapy" 1376:10.4103/0019-5545.64591 1332:Breggin, Peter (1979). 935:Endler, Norman (1988). 519:Psychiatric medications 2380:The Permanente Journal 1741:Subscription required. 591:Deep brain stimulation 321:Psychiatric medication 2629:American Psychologist 2240:10.1093/eurpub/cki159 1685:Mental Health America 1013:10.1192/bjp.161.2.279 876:. Ardent Media. 1969. 586:Bilateral cingulotomy 564:(no longer practiced) 562:Insulin shock therapy 459:Stigmas and treatment 2846:(6 Pt 1): 987–1007. 2610:Mental Health Survey 1723:10.4088/JCP.10m06541 1200:www.encyclopedia.com 1047:(3 Suppl): S22–S27. 975:Psychedelic Press UK 916:www.encyclopedia.com 804:Counselling Resource 539:Antidepressant drugs 51:improve this article 2098:Preventive Medicine 1414:Behavioral Sciences 544:Antipsychotic drugs 515:-based treatments) 2889:10.1007/bf00583999 2392:10.7812/TPP/13-005 2279:Current Psychiatry 2145:The New York Times 1464:www.psychiatry.org 944:Convulsive Therapy 606:-based treatment) 523:psychoactive drugs 499:List of treatments 367:Research completed 182:psychopharmacology 2877:Social Psychiatry 2522:www.helpguide.org 2075:978-1-118-27001-1 1904:"What Are SSRIs?" 1427:10.3390/bs6010005 1343:978-0-8261-2710-5 1147:"Moral Treatment" 784:978-0-205-64524-4 745:978-0-87893-534-5 694:978-0-7884-2024-5 533:Antianxiety drugs 157: 156: 127: 126: 119: 101: 16:(Redirected from 3005: 2998:Mental disorders 2979: 2923: 2922: 2916: 2908: 2872: 2866: 2865: 2855: 2831: 2825: 2824: 2795: 2786: 2785: 2749: 2743: 2742: 2722: 2716: 2709: 2703: 2702: 2701:. 16 April 2013. 2695: 2689: 2688: 2677: 2671: 2670: 2644: 2624: 2613: 2606: 2600: 2586: 2580: 2579: 2577: 2576: 2562: 2556: 2555: 2553: 2552: 2538: 2532: 2531: 2529: 2528: 2514: 2508: 2507: 2505: 2504: 2490: 2484: 2483: 2481: 2480: 2466: 2460: 2459: 2446: 2420: 2414: 2413: 2403: 2371: 2365: 2364: 2353: 2347: 2346: 2320: 2311:(8): 2184–2191. 2296: 2287: 2286: 2270: 2261: 2260: 2242: 2218: 2209: 2208: 2172: 2163: 2162: 2160: 2159: 2136: 2130: 2129: 2095: 2086: 2080: 2079: 2055: 2045: 2039: 2038: 2012: 2003:(sup47): 25–29. 1988: 1975: 1974: 1964: 1939:(1–3): 345–349. 1924: 1918: 1917: 1915: 1914: 1900: 1894: 1893: 1891: 1890: 1876: 1870: 1869: 1867: 1866: 1852: 1846: 1845: 1797: 1791: 1790: 1788: 1787: 1773: 1767: 1766: 1764: 1763: 1748: 1742: 1740: 1738: 1737: 1702: 1696: 1695: 1693: 1692: 1677: 1671: 1670: 1668: 1667: 1656: 1650: 1649: 1647: 1646: 1632: 1626: 1625: 1585: 1579: 1578: 1576: 1575: 1561: 1555: 1554: 1552: 1551: 1540: 1534: 1533: 1531: 1529: 1518: 1512: 1509: 1503: 1502: 1500: 1499: 1490:. 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Index

Treatment of mental illness

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Mental disorders
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Cognitive behavioral therapy
Ladislas Meduna
electroconvulsive therapy
mood stabilizer
antihistamine
antipsychotic
psychotherapy
mental health professional
Cognitive behavioral therapy
dialectical behavior therapy
Psychoanalysis
Systemic therapy
family therapy

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