1977:
253:
42:
479:
The reaction catalyzed by the UGT enzyme involves the addition of a glucuronic acid moiety to xenobiotics and is the most important pathway for the human body's elimination of the most frequently prescribed drugs. It is also the major pathway for foreign chemical (dietary, environmental,
480:
pharmaceutical) removal for most drugs, dietary substances, toxins and endogenous substances. UGT is present in humans, other animals, plants, and bacteria. Famously, UGT enzymes are not present in the genus
730:
Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM (May 2004). "Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands".
826:
Court MH, Greenblatt DJ (2000). "Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms".
1122:
1117:
505:
is more polar (e.g. hydrophilic) and more easily excreted than the substrate molecule. The product solubility in blood is increased allowing it to be eliminated from the body by the
1495:
1371:
906:
Protein
Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics
1162:
376:
207:
1476:
1544:
993:
226:
476:. Arguably the most important of the Phase II (conjugative) enzymes, UGTs have been the subject of increasing scientific inquiry since the mid-to-late 1990s.
1653:
1623:
536:, a more serious disorder where the enzyme's activity is either completely absent (Crigler–Najjar syndrome type I) or less than 10% of normal (type II).
1298:
1293:
934:
494:
1658:
879:
312:
539:
Infants may have a developmental deficiency in UDP-glucuronyl transferase, and are unable to hepatically metabolize the antibiotic drug
986:
1696:
1539:
1549:
219:
1570:
1554:
170:
146:
1852:
928:
926:
924:
396:
979:
257:
Structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.
1967:
1089:
533:
1074:
606:
that are, otherwise, attributed to hepatic bilirubin mal-uptake and bilirubin conjugation compromise, respectively.
1514:
1837:
1953:
1940:
1927:
1914:
1901:
1888:
1875:
1639:
1531:
1444:
1079:
1019:
1847:
164:
1801:
1744:
1084:
1057:
1010:
965:
498:
424:
57:
384:
151:
1749:
1574:
567:
563:
862:
Bock K, Köhle C (2005). "UDP-Glucuronosyltransferase 1A6: Structural, Functional, and
Regulatory Aspects".
1052:
231:
1997:
1770:
1689:
1618:
1104:
1094:
139:
1842:
522:
380:
1486:
1313:
1047:
325:
74:
555:
Causes of unconjugated hyperbilirubinemia are divided into three main categories, namely, excessive
1806:
1448:
1363:
1261:
1034:
1006:
961:
473:
431:
420:
412:
332:
167:
69:
91:
1739:
1601:
1285:
1023:
544:
501:
molecules that contain oxygen, nitrogen, sulfur or carboxyl functional groups. The resulting
2002:
1643:
1069:
971:
885:
875:
844:
783:
748:
599:
595:
571:
371:
158:
1785:
1780:
1754:
1682:
1481:
1468:
1112:
1062:
867:
836:
775:
740:
1353:
1348:
363:
127:
1832:
1816:
1729:
1500:
904:
540:
490:
469:
463:
435:
103:
62:
1981:
1870:
1811:
202:
871:
182:
1991:
1775:
1734:
1505:
1042:
840:
587:
559:
synthesis, liver bilirubin uptake malfunction, and bilirubin conjugation compromise.
317:
177:
281:
1724:
935:"Diagnostic approach to the adult with jaundice or asymptomatic hyperbilirubinemia"
359:
933:
Namita Roy-Chowdhury, Jayanta Roy-Chowdhury. Sanjiv Chopra, Shilpa Grover (eds.).
293:
1948:
1883:
1719:
1002:
502:
186:
1976:
801:
591:
579:
779:
337:
1922:
1896:
603:
556:
518:
889:
848:
787:
752:
766:
King C, Rios G, Green M, Tephly T (2000). "UDP-glucuronosyltransferases".
486:, and this accounts for a number of unusual toxicities in the cat family.
321:
252:
610:
288:
427:
115:
1663:
1521:
1254:
1249:
1244:
1239:
1234:
1202:
1126:
710:
706:
702:
698:
694:
669:
521:
specific form of glucuronosyltransferase is thought to be the cause of
305:
300:
134:
17:
744:
1935:
1705:
1459:
1229:
1224:
1219:
1214:
1209:
1197:
1192:
1187:
1182:
1177:
1172:
1167:
1155:
1150:
1145:
690:
686:
682:
678:
674:
665:
661:
657:
653:
649:
645:
641:
637:
632:
628:
624:
506:
391:
214:
110:
98:
86:
543:
which requires glucuronidation. This leads to a condition known as
1909:
1611:
1606:
1579:
1430:
1381:
1376:
583:
575:
482:
430:) that catalyzes the transfer of the glucuronic acid component of
1425:
1420:
1415:
1410:
1405:
1400:
1393:
1388:
1343:
1338:
1333:
1328:
1323:
1318:
1308:
1303:
1275:
1270:
1265:
353:
276:
122:
1678:
1123:
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
1118:
B-N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase
975:
41:
489:
The glucuronidation reaction consists of the transfer of the
468:
Glucuronosyltransferases are responsible for the process of
1674:
586:
can also lead to indirect hyperbilirubinemia, along with
866:. Methods in Enzymology. Vol. 400. pp. 57–75.
46:
Glucuronosyltransferase monomer, Xanthomonas campestris
1372:
Dolichyl-phosphate-mannose-protein mannosyltransferase
1965:
1861:
1825:
1794:
1763:
1712:
1638:
1594:
1563:
1530:
1467:
1458:
1443:
1362:
1284:
1136:
1103:
1033:
1018:
390:
370:
352:
347:
331:
311:
299:
287:
275:
267:
262:
245:
225:
213:
201:
196:
176:
157:
145:
133:
121:
109:
97:
85:
80:
68:
56:
51:
34:
864:Phase II Conjugation Enzymes and Transport Systems
570:can involve in the pathophysiology. Additionally,
1545:Hypoxanthine-guanine phosphoribosyltransferase
620:Human genes which encode UGT enzymes include:
1690:
987:
246:UDP-glucuronosyl and UDP-glucosyl transferase
8:
1654:Beta-galactoside alpha-2,6-sialyltransferase
409:Uridine 5'-diphospho-glucuronosyltransferase
1624:Indolylacetylinositol arabinosyltransferase
434:to a small hydrophobic molecule. This is a
1697:
1683:
1675:
1464:
1455:
1030:
994:
980:
972:
562:As to excessive bilirubin synthesis, both
344:
251:
193:
964:at the U.S. National Library of Medicine
903:MacDougall C, Chambers HF (2011). "55".
1972:
722:
1659:Monosialoganglioside sialyltransferase
1496:NAD(P):arginine ADP-ribosyltransferase
1477:NAD:diphthamide ADP-ribosyltransferase
242:
31:
7:
909:(12 ed.). New York: McGraw-Hill
495:uridine 5'-diphospho-glucuronic acid
25:
1540:Adenine phosphoribosyltransferase
802:"UDP-glucuronosyltransferase 1-1"
1975:
1550:Uracil phosphoribosyltransferase
841:10.1097/00008571-200006000-00009
40:
1571:Purine nucleoside phosphorylase
527:unconjugated hyperbilirubinemia
1555:Amidophosphoribosyltransferase
1:
872:10.1016/S0076-6879(05)00004-2
348:Available protein structures:
1090:Ceramide glucosyltransferase
525:, which is characterized by
532:It is also associated with
2019:
1515:Poly ADP ribose polymerase
608:
461:
450:UDP-glucuronyl transferase
415:-glucuronosyltransferase,
1853:Michaelis–Menten kinetics
1532:Phosphoribosyltransferase
343:
250:
192:
39:
1745:Diffusion-limited enzyme
1085:1,3-Beta-glucan synthase
966:Medical Subject Headings
780:10.2174/1389200003339171
1575:Thymidine phosphorylase
962:Glucuronosyltransferase
568:extravascular hemolysis
564:intravascular hemolysis
534:Crigler–Najjar syndrome
35:Glucuronosyltransferase
1469:ADP-ribosyltransferase
1838:Eadie–Hofstee diagram
1771:Allosteric regulation
1619:Arabinosyltransferase
1095:N-glycosyltransferase
609:Further information:
578:into tissues such as
574:and extravasation of
447:glucuronyltransferase
1848:Lineweaver–Burk plot
1487:Pseudomonas exotoxin
1007:glycosyltransferases
517:A deficiency in the
1262:Hyaluronan synthase
474:phase II metabolism
432:UDP-glucuronic acid
421:glycosyltransferase
1807:Enzyme superfamily
1740:Enzyme promiscuity
1602:Xylosyltransferase
1075:Debranching enzyme
545:gray baby syndrome
523:Gilbert's syndrome
472:, a major part of
442:Alternative names:
419:) is a microsomal
1963:
1962:
1672:
1671:
1634:
1633:
1590:
1589:
1439:
1438:
1070:Glycogen synthase
881:978-0-12-182805-9
745:10.1021/bi036130c
739:(18): 5170–5180.
600:chronic hepatitis
596:ethinyl estradiol
572:dyserythropoiesis
406:
405:
402:
401:
397:structure summary
241:
240:
237:
236:
140:metabolic pathway
16:(Redirected from
2010:
1980:
1979:
1971:
1843:Hanes–Woolf plot
1786:Enzyme activator
1781:Enzyme inhibitor
1755:Enzyme catalysis
1699:
1692:
1685:
1676:
1482:Diphtheria toxin
1465:
1456:
1113:Lactose synthase
1080:Branching enzyme
1031:
996:
989:
982:
973:
949:
948:
946:
945:
930:
919:
918:
916:
914:
900:
894:
893:
859:
853:
852:
829:Pharmacogenetics
823:
817:
816:
814:
812:
798:
792:
791:
763:
757:
756:
727:
345:
255:
243:
194:
44:
32:
27:Class of enzymes
21:
2018:
2017:
2013:
2012:
2011:
2009:
2008:
2007:
1988:
1987:
1986:
1974:
1966:
1964:
1959:
1871:Oxidoreductases
1857:
1833:Enzyme kinetics
1821:
1817:List of enzymes
1790:
1759:
1730:Catalytic triad
1708:
1703:
1673:
1668:
1645:
1630:
1586:
1559:
1526:
1501:Pertussis toxin
1450:
1435:
1358:
1280:
1132:
1099:
1025:
1014:
1000:
958:
953:
952:
943:
941:
932:
931:
922:
912:
910:
902:
901:
897:
882:
861:
860:
856:
825:
824:
820:
810:
808:
800:
799:
795:
768:Curr Drug Metab
765:
764:
760:
729:
728:
724:
719:
618:
613:
553:
541:chloramphenicol
515:
470:glucuronidation
466:
464:Glucuronidation
460:
436:glucuronidation
258:
47:
28:
23:
22:
15:
12:
11:
5:
2016:
2014:
2006:
2005:
2000:
1990:
1989:
1985:
1984:
1961:
1960:
1958:
1957:
1944:
1931:
1918:
1905:
1892:
1879:
1865:
1863:
1859:
1858:
1856:
1855:
1850:
1845:
1840:
1835:
1829:
1827:
1823:
1822:
1820:
1819:
1814:
1809:
1804:
1798:
1796:
1795:Classification
1792:
1791:
1789:
1788:
1783:
1778:
1773:
1767:
1765:
1761:
1760:
1758:
1757:
1752:
1747:
1742:
1737:
1732:
1727:
1722:
1716:
1714:
1710:
1709:
1704:
1702:
1701:
1694:
1687:
1679:
1670:
1669:
1667:
1666:
1661:
1656:
1650:
1648:
1636:
1635:
1632:
1631:
1629:
1628:
1627:
1626:
1616:
1615:
1614:
1609:
1598:
1596:
1592:
1591:
1588:
1587:
1585:
1584:
1583:
1582:
1567:
1565:
1561:
1560:
1558:
1557:
1552:
1547:
1542:
1536:
1534:
1528:
1527:
1525:
1524:
1518:
1517:
1511:
1510:
1509:
1508:
1503:
1492:
1491:
1490:
1489:
1484:
1473:
1471:
1462:
1453:
1441:
1440:
1437:
1436:
1434:
1433:
1428:
1423:
1418:
1413:
1408:
1403:
1397:
1396:
1391:
1386:
1385:
1384:
1379:
1368:
1366:
1360:
1359:
1357:
1356:
1351:
1346:
1341:
1336:
1331:
1326:
1321:
1316:
1311:
1306:
1301:
1296:
1290:
1288:
1282:
1281:
1279:
1278:
1273:
1268:
1258:
1257:
1252:
1247:
1242:
1237:
1232:
1227:
1222:
1217:
1212:
1206:
1205:
1200:
1195:
1190:
1185:
1180:
1175:
1170:
1165:
1159:
1158:
1153:
1148:
1142:
1140:
1134:
1133:
1131:
1130:
1120:
1115:
1109:
1107:
1101:
1100:
1098:
1097:
1092:
1087:
1082:
1077:
1072:
1067:
1066:
1065:
1060:
1055:
1050:
1039:
1037:
1028:
1016:
1015:
1001:
999:
998:
991:
984:
976:
970:
969:
957:
956:External links
954:
951:
950:
920:
895:
880:
854:
818:
793:
774:(2): 143–161.
758:
721:
720:
718:
715:
714:
713:
672:
635:
617:
614:
552:
549:
514:
511:
462:Main article:
459:
456:
455:
454:
451:
448:
404:
403:
400:
399:
394:
388:
387:
374:
368:
367:
357:
350:
349:
341:
340:
335:
329:
328:
315:
309:
308:
303:
297:
296:
291:
285:
284:
279:
273:
272:
269:
265:
264:
260:
259:
256:
248:
247:
239:
238:
235:
234:
229:
223:
222:
217:
211:
210:
205:
199:
198:
190:
189:
180:
174:
173:
162:
155:
154:
149:
143:
142:
137:
131:
130:
125:
119:
118:
113:
107:
106:
101:
95:
94:
89:
83:
82:
78:
77:
72:
66:
65:
60:
54:
53:
49:
48:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2015:
2004:
2001:
1999:
1996:
1995:
1993:
1983:
1978:
1973:
1969:
1955:
1951:
1950:
1945:
1942:
1938:
1937:
1932:
1929:
1925:
1924:
1919:
1916:
1912:
1911:
1906:
1903:
1899:
1898:
1893:
1890:
1886:
1885:
1880:
1877:
1873:
1872:
1867:
1866:
1864:
1860:
1854:
1851:
1849:
1846:
1844:
1841:
1839:
1836:
1834:
1831:
1830:
1828:
1824:
1818:
1815:
1813:
1812:Enzyme family
1810:
1808:
1805:
1803:
1800:
1799:
1797:
1793:
1787:
1784:
1782:
1779:
1777:
1776:Cooperativity
1774:
1772:
1769:
1768:
1766:
1762:
1756:
1753:
1751:
1748:
1746:
1743:
1741:
1738:
1736:
1735:Oxyanion hole
1733:
1731:
1728:
1726:
1723:
1721:
1718:
1717:
1715:
1711:
1707:
1700:
1695:
1693:
1688:
1686:
1681:
1680:
1677:
1665:
1662:
1660:
1657:
1655:
1652:
1651:
1649:
1647:
1641:
1637:
1625:
1622:
1621:
1620:
1617:
1613:
1610:
1608:
1605:
1604:
1603:
1600:
1599:
1597:
1593:
1581:
1578:
1577:
1576:
1572:
1569:
1568:
1566:
1562:
1556:
1553:
1551:
1548:
1546:
1543:
1541:
1538:
1537:
1535:
1533:
1529:
1523:
1520:
1519:
1516:
1513:
1512:
1507:
1506:Cholera toxin
1504:
1502:
1499:
1498:
1497:
1494:
1493:
1488:
1485:
1483:
1480:
1479:
1478:
1475:
1474:
1472:
1470:
1466:
1463:
1461:
1457:
1454:
1452:
1446:
1442:
1432:
1429:
1427:
1424:
1422:
1419:
1417:
1414:
1412:
1409:
1407:
1404:
1402:
1399:
1398:
1395:
1392:
1390:
1387:
1383:
1380:
1378:
1375:
1374:
1373:
1370:
1369:
1367:
1365:
1361:
1355:
1352:
1350:
1347:
1345:
1342:
1340:
1337:
1335:
1332:
1330:
1327:
1325:
1322:
1320:
1317:
1315:
1312:
1310:
1307:
1305:
1302:
1300:
1297:
1295:
1292:
1291:
1289:
1287:
1283:
1277:
1274:
1272:
1269:
1267:
1263:
1260:
1259:
1256:
1253:
1251:
1248:
1246:
1243:
1241:
1238:
1236:
1233:
1231:
1228:
1226:
1223:
1221:
1218:
1216:
1213:
1211:
1208:
1207:
1204:
1201:
1199:
1196:
1194:
1191:
1189:
1186:
1184:
1181:
1179:
1176:
1174:
1171:
1169:
1166:
1164:
1161:
1160:
1157:
1154:
1152:
1149:
1147:
1144:
1143:
1141:
1139:
1138:Glucuronosyl-
1135:
1128:
1124:
1121:
1119:
1116:
1114:
1111:
1110:
1108:
1106:
1102:
1096:
1093:
1091:
1088:
1086:
1083:
1081:
1078:
1076:
1073:
1071:
1068:
1064:
1061:
1059:
1056:
1054:
1051:
1049:
1046:
1045:
1044:
1043:Phosphorylase
1041:
1040:
1038:
1036:
1032:
1029:
1027:
1021:
1017:
1012:
1008:
1004:
997:
992:
990:
985:
983:
978:
977:
974:
967:
963:
960:
959:
955:
940:
936:
929:
927:
925:
921:
908:
907:
899:
896:
891:
887:
883:
877:
873:
869:
865:
858:
855:
850:
846:
842:
838:
835:(4): 355–69.
834:
830:
822:
819:
807:
803:
797:
794:
789:
785:
781:
777:
773:
769:
762:
759:
754:
750:
746:
742:
738:
734:
726:
723:
716:
712:
708:
704:
700:
696:
692:
688:
684:
680:
676:
673:
671:
667:
663:
659:
655:
651:
647:
643:
639:
636:
634:
630:
626:
623:
622:
621:
615:
612:
607:
605:
601:
597:
593:
589:
588:heart failure
585:
581:
577:
573:
569:
565:
560:
558:
550:
548:
546:
542:
537:
535:
530:
528:
524:
520:
512:
510:
508:
504:
500:
496:
492:
487:
485:
484:
477:
475:
471:
465:
457:
452:
449:
446:
445:
444:
443:
439:
437:
433:
429:
426:
422:
418:
414:
410:
398:
395:
393:
389:
386:
382:
378:
375:
373:
369:
365:
361:
358:
355:
351:
346:
342:
339:
336:
334:
330:
327:
323:
319:
316:
314:
310:
307:
304:
302:
298:
295:
292:
290:
286:
283:
280:
278:
274:
270:
266:
261:
254:
249:
244:
233:
230:
228:
224:
221:
218:
216:
212:
209:
206:
204:
200:
195:
191:
188:
184:
181:
179:
178:Gene Ontology
175:
172:
169:
166:
163:
160:
156:
153:
150:
148:
144:
141:
138:
136:
132:
129:
126:
124:
120:
117:
116:NiceZyme view
114:
112:
108:
105:
102:
100:
96:
93:
90:
88:
84:
79:
76:
73:
71:
67:
64:
61:
59:
55:
50:
43:
38:
33:
30:
19:
1998:Transferases
1949:Translocases
1946:
1933:
1920:
1907:
1894:
1884:Transferases
1881:
1868:
1725:Binding site
1646:transferases
1451:transferases
1137:
1026:transferases
1003:Transferases
942:. Retrieved
938:
911:. Retrieved
905:
898:
863:
857:
832:
828:
821:
809:. Retrieved
805:
796:
771:
767:
761:
736:
733:Biochemistry
732:
725:
619:
561:
554:
538:
531:
526:
516:
491:glucuronosyl
488:
481:
478:
467:
441:
440:
416:
408:
407:
104:BRENDA entry
29:
1720:Active site
1105:Galactosyl-
913:October 19,
811:21 November
503:glucuronide
497:(UDPGA) to
493:group from
263:Identifiers
92:IntEnz view
52:Identifiers
1992:Categories
1923:Isomerases
1897:Hydrolases
1764:Regulation
1058:Cellobiose
944:2019-07-17
717:References
594:-induced,
592:medication
580:angioedema
438:reaction.
360:structures
333:Membranome
161:structures
128:KEGG entry
75:9030-08-4
1802:EC number
1449:Pentosyl-
1364:Mannosyl-
1035:Glucosyl-
604:cirrhosis
557:bilirubin
519:bilirubin
499:substrate
306:PDOC00359
294:IPR002213
81:Databases
2003:EC 2.4.1
1826:Kinetics
1750:Cofactor
1713:Activity
1286:Fucosyl-
1053:Glycogen
1024:Hexosyl-
939:UpToDate
890:16399343
849:10862526
806:Drugbank
788:11465080
753:15122882
611:Jaundice
513:Diseases
458:Function
428:2.4.1.17
377:RCSB PDB
289:InterPro
232:proteins
220:articles
208:articles
165:RCSB PDB
63:2.4.1.17
1982:Biology
1936:Ligases
1706:Enzymes
1664:ST8SIA4
1522:Sirtuin
1255:UGT2B28
1250:UGT2B17
1245:UGT2B15
1240:UGT2B11
1235:UGT2B10
1203:UGT1A10
1127:C1GALT1
711:UGT2B28
707:UGT2B17
703:UGT2B15
699:UGT2B11
695:UGT2B10
670:UGT1A10
507:kidneys
301:PROSITE
282:PF00201
187:QuickGO
152:profile
135:MetaCyc
70:CAS no.
18:UGT2B28
1968:Portal
1910:Lyases
1644:Sialyl
1640:2.4.99
1460:Ribose
1299:POFUT2
1294:POFUT1
1230:UGT2B7
1225:UGT2B4
1220:UGT2A3
1215:UGT2A2
1210:UGT2A1
1198:UGT1A9
1193:UGT1A8
1188:UGT1A7
1183:UGT1A6
1178:UGT1A5
1173:UGT1A4
1168:UGT1A3
1163:UGT1A1
1156:B3GAT3
1151:B3GAT2
1146:B3GAT1
1048:Starch
968:(MeSH)
888:
878:
847:
786:
751:
691:UGT2B7
687:UGT2B4
683:UGT2A3
679:UGT2A2
675:UGT2A1
666:UGT1A9
662:UGT1A8
658:UGT1A7
654:UGT1A6
650:UGT1A5
646:UGT1A4
642:UGT1A3
638:UGT1A1
633:B3GAT3
629:B3GAT2
625:B3GAT1
602:, and
551:Causes
453:UDP-GT
392:PDBsum
366:
356:
326:SUPFAM
268:Symbol
215:PubMed
197:Search
183:AmiGO
171:PDBsum
111:ExPASy
99:BRENDA
87:IntEnz
58:EC no.
1862:Types
1612:XYLT2
1607:XYLT1
1595:Other
1580:ECGF1
1564:Other
1445:2.4.2
1431:ALG12
1382:POMT2
1377:POMT1
1354:FUT11
1349:FUT10
1020:2.4.1
616:Genes
584:edema
576:blood
483:Felis
322:SCOPe
313:SCOP2
271:UDPGT
147:PRIAM
1954:list
1947:EC7
1941:list
1934:EC6
1928:list
1921:EC5
1915:list
1908:EC4
1902:list
1895:EC3
1889:list
1882:EC2
1876:list
1869:EC1
1426:ALG9
1421:ALG8
1416:ALG6
1411:ALG3
1406:ALG2
1401:ALG1
1394:DPM3
1389:DPM1
1344:FUT9
1339:FUT8
1334:FUT7
1329:FUT6
1324:FUT5
1319:FUT4
1314:FUT3
1309:FUT2
1304:FUT1
1276:HAS3
1271:HAS2
1266:HAS1
1063:Myo-
1013:2.4)
915:2011
886:PMID
876:ISBN
845:PMID
813:2019
784:PMID
749:PMID
582:and
566:and
385:PDBj
381:PDBe
364:ECOD
354:Pfam
318:1rrv
277:Pfam
227:NCBI
168:PDBe
123:KEGG
868:doi
837:doi
776:doi
741:doi
417:UGT
413:UDP
372:PDB
338:476
203:PMC
159:PDB
1994::
1642::
1573::
1447::
1264::
1022::
1011:EC
1005::
937:.
923:^
884:.
874:.
843:.
833:10
831:.
804:.
782:.
770:.
747:.
737:43
735:.
709:,
705:,
701:,
697:,
693:,
689:,
685:,
681:,
677:,
668:,
664:,
660:,
656:,
652:,
648:,
644:,
640:,
631:,
627:,
598:,
590:,
547:.
529:.
509:.
425:EC
383:;
379:;
362:/
324:/
320:/
185:/
1970::
1956:)
1952:(
1943:)
1939:(
1930:)
1926:(
1917:)
1913:(
1904:)
1900:(
1891:)
1887:(
1878:)
1874:(
1698:e
1691:t
1684:v
1129:)
1125:(
1009:(
995:e
988:t
981:v
947:.
917:.
892:.
870::
851:.
839::
815:.
790:.
778::
772:1
755:.
743::
423:(
411:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
