297:
274:
171:
196:
548:
303:
202:
1926:
50:
1534:
Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human retina for the NEIBank
Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts".
310:
209:
1409:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
861:
842:
132:
1995:
1971:
1990:
1269:
1251:
1380:
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
296:
1077:
1084:
273:
1830:"Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin"
1783:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
1333:
1871:
Joo HY, Zhai L, Yang C, et al. (2007). "Regulation of cell cycle progression and gene expression by H2A deubiquitination".
1238:
1217:
195:
170:
1234:
47:
1287:
Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach".
1213:
112:
309:
208:
1964:
302:
201:
906:
120:
1742:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
1154:
887:
1957:
184:
1440:"A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division"
1880:
1792:
1700:
1569:
1504:
1451:
1190:
99:
1035:
1031:
984:
980:
1904:
1816:
1312:
144:
1558:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
1351:
D'Andrea A, Pellman D (1999). "Deubiquitinating enzymes: a new class of biological regulators".
1060:
1039:
1005:
976:
1896:
1859:
1808:
1771:
1728:
1675:
1632:
1597:
1544:
1522:
1479:
1426:
1397:
1368:
1304:
1166:
547:
92:
40:
1941:
1888:
1849:
1841:
1800:
1761:
1753:
1718:
1708:
1665:
1657:
1622:
1587:
1577:
1512:
1469:
1459:
1418:
1389:
1360:
1296:
389:
320:
264:
219:
140:
1158:
364:
1884:
1796:
1704:
1573:
1508:
1455:
1854:
1829:
1766:
1741:
1723:
1688:
1670:
1645:
1592:
1557:
1422:
776:
771:
766:
761:
756:
751:
746:
741:
736:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
681:
676:
660:
655:
650:
634:
629:
624:
619:
614:
609:
604:
599:
594:
589:
1984:
1937:
1474:
1439:
1393:
1186:
576:
124:
1908:
1820:
1316:
382:
161:
148:
1274:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1256:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1178:
465:
1845:
1364:
281:
178:
128:
1713:
1611:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1182:
1170:
806:
525:
403:
348:
335:
247:
234:
136:
1900:
1863:
1812:
1775:
1732:
1679:
1636:
1601:
1582:
1548:
1526:
1483:
1464:
1308:
1430:
1401:
1372:
1124:
1119:
1174:
1108:
951:
932:
1892:
1804:
1757:
1661:
1162:
918:
873:
69:
1517:
1492:
1140:
1092:
828:
1925:
1300:
1689:"Large-scale characterization of HeLa cell nuclear phosphoproteins"
1627:
1610:
791:
787:
1933:
1147:
556:
116:
1687:
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
1185:, in vitro and a mutant form of the protein was shown to block
1646:"A protein interaction framework for human mRNA degradation"
1556:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
727:
positive regulation of transcription by RNA polymerase II
1193:, encoding different isoforms, have been characterized.
372:
1945:
1740:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1491:
Hattori M, Fujiyama A, Taylor TD, et al. (2000).
537:
1334:"Entrez Gene: USP16 ubiquitin specific peptidase 16"
1053:
1024:
998:
969:
737:
positive regulation of transcription, DNA-templated
1609:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1230:
1228:
1226:
1209:
1207:
1205:
1828:Pai MT, Tzeng SR, Kovacs JJ, et al. (2007).
319:
218:
692:regulation of transcription by RNA polymerase II
687:positive regulation of translational elongation
16:Protein-coding gene in the species Homo sapiens
1235:GRCm38: Ensembl release 89: ENSMUSG00000025616
697:monoubiquitinated histone H2A deubiquitination
103:, UBP-M, UBPM, ubiquitin specific peptidase 16
1965:
1181:, one of two major ubiquitinated proteins of
682:ubiquitin-dependent protein catabolic process
8:
1214:GRCh38: Ensembl release 89: ENSG00000156256
1972:
1958:
802:
677:regulation of transcription, DNA-templated
572:
360:
259:
156:
58:
1853:
1765:
1722:
1712:
1669:
1626:
1591:
1581:
1516:
1493:"The DNA sequence of human chromosome 21"
1473:
1463:
1438:Cai SY, Babbitt RW, Marchesi VT (1999).
1328:
1326:
1137:Ubiquitin carboxyl-terminal hydrolase 16
712:cellular response to DNA damage stimulus
1201:
722:histone H2A K63-linked deubiquitination
18:
324:
285:
280:
223:
182:
177:
7:
1922:
1920:
620:cysteine-type endopeptidase activity
1944:. You can help Knowledge (XXG) by
1177:transition. It can deubiquitinate
1050:
1021:
995:
966:
942:
923:
897:
878:
852:
833:
615:transcription coactivator activity
542:
460:
398:
377:
14:
1143:that in humans is encoded by the
1924:
590:cysteine-type peptidase activity
546:
308:
301:
295:
272:
207:
200:
194:
169:
1644:Lehner B, Sanderson CM (2004).
1191:transcriptional splice variants
1996:Human chromosome 21 gene stubs
635:thiol-dependent deubiquitinase
557:More reference expression data
526:More reference expression data
1:
1423:10.1016/S0378-1119(97)00411-3
1353:Crit. Rev. Biochem. Mol. Biol
747:regulation of gene expression
293:
192:
1991:Genes on human chromosome 21
1693:Proc. Natl. Acad. Sci. U.S.A
1562:Proc. Natl. Acad. Sci. U.S.A
1444:Proc. Natl. Acad. Sci. U.S.A
1394:10.1016/0378-1119(94)90802-8
702:transcription, DNA-templated
742:protein homotetramerization
2012:
1919:
1846:10.1016/j.jmb.2007.04.015
1365:10.1080/10409239891204251
1270:"Mouse PubMed Reference:"
1252:"Human PubMed Reference:"
1123:
1118:
1114:
1107:
1091:
1072:
1057:
1028:
1017:
1002:
973:
962:
949:
945:
930:
926:
917:
904:
900:
885:
881:
872:
859:
855:
840:
836:
827:
812:
805:
801:
785:
575:
571:
554:
545:
536:
523:
472:
463:
422:epithelium of nasopharynx
410:
401:
371:
363:
359:
342:
329:
292:
271:
262:
258:
241:
228:
191:
168:
159:
155:
110:
107:
97:
90:
85:
66:
61:
44:
39:
34:
30:
26:
21:
1085:Chr 16: 87.45 – 87.48 Mb
1078:Chr 21: 29.02 – 29.05 Mb
777:mitotic nuclear division
757:regulation of cell cycle
752:histone deubiquitination
732:protein deubiquitination
442:tendon of biceps brachii
1714:10.1073/pnas.0404720101
1155:deubiquitinating enzyme
1583:10.1073/pnas.242603899
1465:10.1073/pnas.96.6.2828
767:chromatin organization
287:Chromosome 16 (mouse)
185:Chromosome 21 (human)
1153:This gene encodes a
62:List of PDB id codes
35:Available structures
1893:10.1038/nature06256
1885:2007Natur.449.1068J
1805:10.1038/nature04209
1797:2005Natur.437.1173R
1705:2004PNAS..10112130B
1574:2002PNAS...9916899M
1509:2000Natur.405..311H
1456:1999PNAS...96.2828C
500:seminiferous tubule
438:epithelium of colon
1932:This article on a
1758:10.1101/gr.2596504
1662:10.1101/gr.2122004
907:ENSMUSG00000025616
762:mitotic cell cycle
670:Biological process
644:Cellular component
610:hydrolase activity
605:peptidase activity
583:Molecular function
1953:
1952:
1879:(7165): 1068–72.
1568:(26): 16899–903.
1134:
1133:
1130:
1129:
1103:
1102:
1068:
1067:
1047:
1046:
1013:
1012:
992:
991:
958:
957:
939:
938:
913:
912:
894:
893:
868:
867:
849:
848:
797:
796:
630:ubiquitin binding
600:metal ion binding
567:
566:
563:
562:
532:
531:
519:
518:
457:
456:
355:
354:
254:
253:
149:USP16 - orthologs
81:
80:
77:
76:
45:Ortholog search:
2003:
1974:
1967:
1960:
1928:
1921:
1912:
1867:
1857:
1824:
1791:(7062): 1173–8.
1779:
1769:
1736:
1726:
1716:
1683:
1673:
1640:
1630:
1605:
1595:
1585:
1552:
1530:
1520:
1518:10.1038/35012518
1487:
1477:
1467:
1434:
1405:
1376:
1338:
1337:
1330:
1321:
1320:
1284:
1278:
1277:
1266:
1260:
1259:
1248:
1242:
1232:
1221:
1211:
1167:dephosphorylated
1161:at the onset of
1116:
1115:
1087:
1080:
1063:
1051:
1042:
1022:
1018:RefSeq (protein)
1008:
996:
987:
967:
943:
924:
898:
879:
853:
834:
803:
595:zinc ion binding
573:
559:
550:
543:
528:
512:seminal vesicula
488:genital tubercle
468:
466:Top expressed in
461:
434:secondary oocyte
406:
404:Top expressed in
399:
378:
361:
351:
338:
327:
312:
305:
299:
288:
276:
260:
250:
237:
226:
211:
204:
198:
187:
173:
157:
151:
102:
95:
72:
59:
53:
32:
31:
19:
2011:
2010:
2006:
2005:
2004:
2002:
2001:
2000:
1981:
1980:
1979:
1978:
1917:
1915:
1870:
1827:
1782:
1752:(10B): 2121–7.
1739:
1699:(33): 12130–5.
1686:
1643:
1608:
1555:
1533:
1503:(6784): 311–9.
1490:
1437:
1417:(1–2): 149–56.
1408:
1379:
1350:
1346:
1344:Further reading
1341:
1332:
1331:
1324:
1301:10.1038/nrg1111
1286:
1285:
1281:
1268:
1267:
1263:
1250:
1249:
1245:
1233:
1224:
1212:
1203:
1199:
1125:View/Edit Mouse
1120:View/Edit Human
1083:
1076:
1073:Location (UCSC)
1059:
1038:
1034:
1030:
1004:
983:
979:
975:
888:ENSG00000156256
781:
665:
639:
625:histone binding
555:
524:
515:
510:
506:
502:
498:
496:muscle of thigh
494:
490:
486:
482:
478:
464:
453:
448:
446:parietal pleura
444:
440:
436:
432:
428:
426:Achilles tendon
424:
420:
416:
402:
346:
333:
326:16|16 C3.3
325:
315:
314:
313:
306:
286:
263:Gene location (
245:
232:
224:
214:
213:
212:
205:
183:
160:Gene location (
111:
98:
91:
68:
46:
17:
12:
11:
5:
2009:
2007:
1999:
1998:
1993:
1983:
1982:
1977:
1976:
1969:
1962:
1954:
1951:
1950:
1929:
1914:
1913:
1868:
1840:(2): 290–302.
1825:
1780:
1737:
1684:
1656:(7): 1315–23.
1641:
1628:10.1038/ng1285
1606:
1553:
1531:
1488:
1450:(6): 2828–33.
1435:
1406:
1388:(1–2): 171–4.
1377:
1347:
1345:
1342:
1340:
1339:
1322:
1279:
1261:
1243:
1222:
1200:
1198:
1195:
1159:phosphorylated
1132:
1131:
1128:
1127:
1122:
1112:
1111:
1105:
1104:
1101:
1100:
1098:
1096:
1089:
1088:
1081:
1074:
1070:
1069:
1066:
1065:
1055:
1054:
1048:
1045:
1044:
1026:
1025:
1019:
1015:
1014:
1011:
1010:
1000:
999:
993:
990:
989:
971:
970:
964:
960:
959:
956:
955:
947:
946:
940:
937:
936:
928:
927:
921:
915:
914:
911:
910:
902:
901:
895:
892:
891:
883:
882:
876:
870:
869:
866:
865:
857:
856:
850:
847:
846:
838:
837:
831:
825:
824:
819:
814:
810:
809:
799:
798:
795:
794:
783:
782:
780:
779:
774:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
684:
679:
673:
671:
667:
666:
664:
663:
658:
653:
647:
645:
641:
640:
638:
637:
632:
627:
622:
617:
612:
607:
602:
597:
592:
586:
584:
580:
579:
569:
568:
565:
564:
561:
560:
552:
551:
540:
534:
533:
530:
529:
521:
520:
517:
516:
514:
513:
509:
505:
501:
497:
493:
489:
485:
484:tail of embryo
481:
477:
473:
470:
469:
458:
455:
454:
452:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
411:
408:
407:
395:
394:
386:
375:
369:
368:
365:RNA expression
357:
356:
353:
352:
344:
340:
339:
331:
328:
323:
317:
316:
307:
300:
294:
290:
289:
284:
278:
277:
269:
268:
256:
255:
252:
251:
243:
239:
238:
230:
227:
222:
216:
215:
206:
199:
193:
189:
188:
181:
175:
174:
166:
165:
153:
152:
109:
105:
104:
96:
88:
87:
83:
82:
79:
78:
75:
74:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2008:
1997:
1994:
1992:
1989:
1988:
1986:
1975:
1970:
1968:
1963:
1961:
1956:
1955:
1949:
1947:
1943:
1939:
1938:chromosome 21
1935:
1930:
1927:
1923:
1918:
1910:
1906:
1902:
1898:
1894:
1890:
1886:
1882:
1878:
1874:
1869:
1865:
1861:
1856:
1851:
1847:
1843:
1839:
1835:
1831:
1826:
1822:
1818:
1814:
1810:
1806:
1802:
1798:
1794:
1790:
1786:
1781:
1777:
1773:
1768:
1763:
1759:
1755:
1751:
1747:
1743:
1738:
1734:
1730:
1725:
1720:
1715:
1710:
1706:
1702:
1698:
1694:
1690:
1685:
1681:
1677:
1672:
1667:
1663:
1659:
1655:
1651:
1647:
1642:
1638:
1634:
1629:
1624:
1620:
1616:
1612:
1607:
1603:
1599:
1594:
1589:
1584:
1579:
1575:
1571:
1567:
1563:
1559:
1554:
1550:
1546:
1542:
1538:
1532:
1528:
1524:
1519:
1514:
1510:
1506:
1502:
1498:
1494:
1489:
1485:
1481:
1476:
1471:
1466:
1461:
1457:
1453:
1449:
1445:
1441:
1436:
1432:
1428:
1424:
1420:
1416:
1412:
1407:
1403:
1399:
1395:
1391:
1387:
1383:
1378:
1374:
1370:
1366:
1362:
1359:(5): 337–52.
1358:
1354:
1349:
1348:
1343:
1335:
1329:
1327:
1323:
1318:
1314:
1310:
1306:
1302:
1298:
1295:(7): 544–58.
1294:
1290:
1289:Nat Rev Genet
1283:
1280:
1275:
1271:
1265:
1262:
1257:
1253:
1247:
1244:
1240:
1236:
1231:
1229:
1227:
1223:
1219:
1215:
1210:
1208:
1206:
1202:
1196:
1194:
1192:
1188:
1187:cell division
1184:
1180:
1176:
1172:
1168:
1164:
1160:
1156:
1151:
1149:
1146:
1142:
1138:
1126:
1121:
1117:
1113:
1110:
1106:
1099:
1097:
1094:
1090:
1086:
1082:
1079:
1075:
1071:
1064:
1062:
1056:
1052:
1049:
1043:
1041:
1037:
1033:
1027:
1023:
1020:
1016:
1009:
1007:
1001:
997:
994:
988:
986:
982:
978:
972:
968:
965:
963:RefSeq (mRNA)
961:
954:
953:
948:
944:
941:
935:
934:
929:
925:
922:
920:
916:
909:
908:
903:
899:
896:
890:
889:
884:
880:
877:
875:
871:
864:
863:
858:
854:
851:
845:
844:
839:
835:
832:
830:
826:
823:
820:
818:
815:
811:
808:
804:
800:
793:
789:
784:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
753:
750:
748:
745:
743:
740:
738:
735:
733:
730:
728:
725:
723:
720:
718:
717:cell division
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
683:
680:
678:
675:
674:
672:
669:
668:
662:
659:
657:
654:
652:
649:
648:
646:
643:
642:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
601:
598:
596:
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577:Gene ontology
574:
570:
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544:
541:
539:
535:
527:
522:
511:
508:soleus muscle
507:
504:parotid gland
503:
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1946:expanding it
1931:
1916:
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1834:J. Mol. Biol
1833:
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1282:
1273:
1264:
1255:
1246:
1189:. Alternate
1152:
1144:
1136:
1135:
1058:
1036:NP_001027582
1032:NP_001001992
1029:
1003:
985:NM_001032410
981:NM_001001992
974:
950:
931:
905:
886:
860:
841:
821:
816:
388:
381:
108:External IDs
67:
1621:(1): 40–5.
1543:: 196–204.
707:proteolysis
661:nucleoplasm
347:87,483,517
334:87,454,703
246:29,054,488
233:29,024,629
86:Identifiers
1985:Categories
1746:Genome Res
1650:Genome Res
1615:Nat. Genet
1241:, May 2017
1220:, May 2017
1197:References
772:cell cycle
392:(ortholog)
129:HomoloGene
1936:on human
1183:chromatin
1171:metaphase
1165:and then
1061:NP_077220
1040:NP_006438
1006:NM_024258
977:NM_006447
807:Orthologs
651:cytoplasm
492:spermatid
137:GeneCards
1901:17914355
1864:17512543
1813:16189514
1776:15489334
1733:15302935
1680:15231747
1637:14702039
1602:12477932
1549:12107411
1537:Mol. Vis
1527:10830953
1484:10077596
1309:12838346
1237:–
1216:–
1175:anaphase
1157:that is
1109:Wikidata
786:Sources:
1909:4417239
1881:Bibcode
1855:2870993
1821:4427026
1793:Bibcode
1701:Bibcode
1570:Bibcode
1505:Bibcode
1452:Bibcode
1431:9373149
1402:8125298
1373:9827704
1317:2856065
1239:Ensembl
1218:Ensembl
1169:at the
1163:mitosis
919:UniProt
874:Ensembl
813:Species
792:QuickGO
656:nucleus
430:pylorus
367:pattern
225:21q21.3
125:1921362
93:Aliases
1907:
1899:
1873:Nature
1862:
1852:
1819:
1811:
1785:Nature
1774:
1767:528928
1764:
1731:
1724:514446
1721:
1678:
1671:442147
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1600:
1593:139241
1590:
1547:
1525:
1497:Nature
1482:
1472:
1429:
1400:
1371:
1315:
1307:
1141:enzyme
1139:is an
1095:search
1093:PubMed
952:Q99LG0
933:Q9Y5T5
829:Entrez
538:BioGPS
480:morula
476:zygote
450:cardia
414:oocyte
117:604735
1940:is a
1905:S2CID
1817:S2CID
1475:15854
1313:S2CID
1145:USP16
862:74112
843:10600
822:Mouse
817:Human
788:Amigo
418:sperm
390:Mouse
383:Human
330:Start
265:Mouse
229:Start
162:Human
141:USP16
133:38183
100:USP16
22:USP16
1942:stub
1934:gene
1897:PMID
1860:PMID
1809:PMID
1772:PMID
1729:PMID
1676:PMID
1633:PMID
1598:PMID
1545:PMID
1523:PMID
1480:PMID
1427:PMID
1411:Gene
1398:PMID
1382:Gene
1369:PMID
1305:PMID
1148:gene
373:Bgee
321:Band
282:Chr.
220:Band
179:Chr.
113:OMIM
70:2I50
51:RCSB
48:PDBe
1889:doi
1877:449
1850:PMC
1842:doi
1838:370
1801:doi
1789:437
1762:PMC
1754:doi
1719:PMC
1709:doi
1697:101
1666:PMC
1658:doi
1623:doi
1588:PMC
1578:doi
1513:doi
1501:405
1470:PMC
1460:doi
1419:doi
1415:200
1390:doi
1386:138
1361:doi
1297:doi
1179:H2A
343:End
242:End
145:OMA
121:MGI
41:PDB
1987::
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790:/
349:bp
336:bp
248:bp
235:bp
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1973:e
1966:t
1959:v
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