467:—to continue to build on this research in 2005, marking the largest nationally competitive NIH grant awarded to the university. NIH reviewers rated the proposed research program as exceedingly innovative and potentially high-impact, noting that it addresses an extremely important clinical problem in a way that will move treatments from the laboratory to the patient as quickly as possible. Using highly unusual language, the reviewers called the proposal "a paradigm of what a program project grant should be." Dr Bolli was the lead author on the SCIPIO trial testing the effects of stem cells in heart failure. The resulting paper was retracted by
262:
322:, where health-related study and research would take place and the School of Medicine would be located. The Health Sciences Center included a 120,000-square-foot Medical-Dental Research Building (opened in 1963), new buildings to house the medical and dental schools, a library, and laboratory buildings. Vice President for health affairs Harold Boyer oversaw state appropriation of funds for the construction of a new teaching hospital and ambulatory care center.
1917:
2164:
380:
1931:
659:
the basic research departments in the School of
Medicine: Biochemistry & Molecular Biology, Pharmacology & Toxicology, Anatomy & Neurobiology, Microbiology & Immunology and Physiology & Biophysics. Arrangements can be made in special cases to design a program based in one of the degree-granting programs located at UofL's Belknap Campus.
31:
618:
Brown Cancer Center scientists have developed three novel cancer treatments that are in early phase trials. Additionally, at least twenty-seven new drugs or targets which are in various stages of preclinical testing have also been developed. These treatments mark one of the most robust pipelines of
252:
Theodore Stout Bell, a prominent physician at
Transylvania Medical Institute, helped initiate this faculty transfer by suggesting that Louisville would have better clinical cadavers for medical study than Lexington. Classes at the Louisville Medical Institute began in temporary quarters in fall 1837,
221:
in the world, the first five hand transplants in the United States and nine hand transplants in eight recipients as of 2008, the first discovery of embryonic-like stem cells in adult human bone marrow, and the first proof that adult nasal stem cells can grow to become other types of cells. In 2013,
658:
The School of
Medicine offers several joint degree programs including MD/MA through the Interdisciplinary Master of Arts in Bioethics and Medical Humanities, MD/MS through the School of Public Health & Information Sciences, MD/MBA through the UofL College of Business, and MD/PhD through any of
631:
The general applicant pool has become increasingly competitive. Kentucky residents are selected for 120 of the approximately 155 seats in the School of
Medicine program each year. Out of state seats are awarded to those with superior academic achievement, MCAT scores, research, community service
325:
In 1997, the
Kentucky General Assembly approved House Bill 1, also known as the Higher Education Reform Act. It included the mandate that the University of Louisville become a premier metropolitan research university by 2020. Today, the Health Sciences Center features over 200,000 square feet of
257:
eight months later. Clinical teaching took part in the wards of
Louisville City Hospital (now University Hospital). By the early 1840s, University of Louisville School of Medicine had become a distinguished center for medical education, attracting students from a wide variety of locations in the
590:
James Graham Brown Cancer researchers used laboratory findings to design a clinical trial in which the cardiac drug, digoxin, is used as a supplement of chemotherapy treatment. Early results from the trial suggested the treatment will result in the highest response rate for melanoma ever
619:
any cancer center in the world. Accordingly, a biotech company partially owned by the
University of Louisville/Brown Cancer Center, Advanced Cancer Therapeutics, has been initiated to ensure drugs are developed locally and quickly. The goal of the cancer center is to achieve
249:) called for a medical school to be founded in Louisville. The city government appropriated funds for a new medical school at Eighth and Chestnut Streets. Much of the Louisville Medical Institute's early faculty came from Transylvania Medical Institute in Lexington, Kentucky.
563:
Drs. A. Bennett Jenson and Shin-je Ghim, innovators of the world's first 100% effective cancer vaccine have begun work to develop a less expensive vaccine with an increased spectrum of activity. This vaccine will be produced in tobacco plants, one of
Kentucky's abundant
274:
In 1846, by ruling of the
Kentucky Legislature, the Louisville Medical Institute became the Medical Department of the newly founded University of Louisville. Many notably physicians and researchers became affiliated with the medical department, including
599:
Brown Cancer researchers, led by Dr. Gordon Ross, discovered that beta-glucan can markedly enhance the immune response of mice to injected tumors. This treatment is now being tested for the first time in humans at the
University of Louisville and
329:
There are five hospitals within walking distance of the Health Sciences Center campus, with the VA Hospital 5 minutes away, where students perform their clinical rotations. The Louisville Medical Center serves more than 500,000 patients each year:
1970:
547:
The James Graham Brown Cancer Center, an affiliate of Kentucky One Health and University of Louisville School of Medicine, has made several discoveries that have brought the center international attention. These discoveries include:
572:
Drs. Trent and Bates discovered a new growth inhibitor activity of G-rich oligonucleotides which have proved effective in early phase clinical trials with no toxicity noted in humans. The drug, AS1411, is now in Phase II clinical
1352:
1321:
302:
joined the faculty of the University of Louisville School of Medicine as the first African American women on staff towards ending racial segregation in Louisville area hospitals and medical professional organizations.
432:
Throughout its history, the University of Louisville School of Medicine has been a pioneer in terms of modern medical practice and surgical procedure. Notably, the University of Louisville housed the world's first
1963:
581:
Scientists in the Structural Biology Program have used nuclear magnetic resonance (NMR) to follow glucose metabolized by patients with lung cancer to demonstrate differences between normal and malignant lung
1956:
483:
He has been a member of numerous NIH study sections and committees and is a member of the NHLBI Advisory Council. He also serves as a member of the Board of Directors of the American Heart Association.
229:
The school offers several dual degree programs including MD/MS, MD/MA, MD/MBA, MD/MPH, and MD/PhD degrees. For the 2017 entering class, 162 students enrolled in the Doctor of Medicine (M.D.) program.
1106:
918:
397:
1409:
242:
By the early 1830s, Louisville had become a center for inland transportation into the United States. Seeking to develop cultural institutions, citizens (notably town trustee and future
830:
1344:
863:
1313:
2225:
800:
Horine, Emmet Field (July 1933). "A History of the Louisville Medical Institute and of the Establishment of the University of Louisville and Its School of Medicine, 1833–1846".
555:
These "embryonic-like" stem cells, which are isolated from bone marrow, will revolutionize clinical applications of stem cells and further the understanding of cancer metastasis
1054:
612:
Dr. Ramesh Gupta is the first to show that colored berries can prevent the development of cancer in animals and is preparing the first human clinical trial using this approach.
517:
In 2001, University of Louisville and Jewish Hospital physicians and researchers, Drs. Laman A. Gray Jr. and Robert D. Dowling, performed the world's first implantation of the
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state-of-the-art research facilities, a standardized patient clinic and one of the largest academic medical simulation centers in the United States.
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Surgeons from the University of Louisville in cooperation with the Kleinert and Kutz Hand Care Center and Jewish Hospital performed the first five
2078:
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691:
243:
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601:
820:
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500:
514:. The Christine M. Kleinert Institute hand surgery fellowship program is one of the top fellowships in the world for hand and microsurgery.
2220:
480:
1762:
853:
1748:
750:
521:
Implantable Replacement Heart on July 2, in a seven-hour procedure at Jewish Hospital in Louisville, Kentucky. University of Louisville
318:
The 1960s saw a period of major growth in the University of Louisville Medical Department. University officials began construction of a
246:
226:
ranked the University of Louisville School of Medicine #76 in research in its annual list of Best Medical Schools in the United States.
1675:
1934:
1050:
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for data falsification, He is or has been on the editorial board of all major cardiovascular journals and was the Editor in Chief of
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1920:
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1014:
959:
419:
1128:
888:
1776:
1491:
1238:"Retraction—Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial"
1214:
1806:
499:, first bilateral upper arm replantation, first bilateral forearm replantation, first reported successful technique for primary
2033:
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1435:
261:
1457:
401:
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456:
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2013:
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319:
187:
69:
1878:
522:
1374:
441:, the process by which a person receives their own blood for a transfusion rather than banked donor blood.
210:
in 1837, it is one of the oldest medical schools in North America and the 9th oldest in the United States.
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2139:
2003:
1820:
1704:
1287:
459:(AHA) conference. Dr. Bolli also headed a U of L team that was awarded an $ 11.7 million grant from the
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91:
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University of Louisville researchers achieved the first implantation of the first fully self-contained
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2008:
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724:
537:
511:
475:
299:
292:
1345:"Boyett: Local woman's loss of both arms led to pioneer reattachment surgery at Louisville hospital"
2103:
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951:
745:
76:
2144:
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1998:
858:
825:
740:
437:, opened in 1911 and developed by surgeon Arnold Griswold in the 1930s. Griswold also developed
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218:
2018:
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Upon matriculation, each incoming student is assigned to one of six Advisory Colleges.
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in the United States. The Hand Center performed one of the world's first cross-hand
504:
492:
276:
1155:"History of the School of Medicine — School of Medicine University of Louisville"
1000:
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379:
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1979:
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111:
30:
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First use of digoxin to enhance the effects of chemotherapy in lung cancer
642:
An average MCAT score of 10 in each test area; O in Writing Sample (30/O)
530:
510:
transfer. This center has pioneered work in primary reconstruction using
448:
199:
117:
609:
First use of colored berries to prevent cancer in high risk individuals
596:
First use of beta-glucan as an immunostimulant for human cancer therapy
569:
First clinical use of G-rich oligonucleotide aptamer therapy for cancer
455:. This group presented its findings to 40,000 cardiologists at the 1998
1983:
710:, American sexologist and professor of anatomy and reproductive biology
525:
have performed many other novel procedures, including Kentucky's first
518:
404: in this section. Unsourced material may be challenged and removed.
1186:"U of L criticizes professor's homophobic email to Louisville Ballet"
623:
designation, a goal they are on track to receive in the near future.
578:
First atomic-level study of lung cancer metabolism in human patients
1103:"University of Louisville | Best Medical School | US News"
1517:
821:"Self-Contained Mechanical Heart Throbs for First Time in a Human"
169:
444:
In 1998, Dr. Roberto Bolli led a U of L team that identified an
1952:
1528:
639:
An overall GPA of 3.64; with BCPM (science) GPA average of 3.56
253:
eventually moving to a building designed by Kentucky architect
854:"Doctors in Louisville Perform Nation's First Hand Transplant"
648:
32 of the matriculates were University of Louisville graduates
373:
529:, the world's first heart transplant following the use of a
479:, a post from which he was dismissed for making homophobic
1314:"Surgeon known for first hand transplant in US dead at 92"
552:
First description of Very Small Embryonic-like Stem Cells
310:
was selected as the next dean of the School of Medicine.
1051:"Dr. Toni Ganzel named dean of UofL School of Medicine"
2150:
Western Kentucky University-Fort Knox regional campus
2024:
Eastern Kentucky University-Fort Knox regional campus
1375:"Christine M Kleinert Institute Fellowship Programs"
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First development of a tobacco-based cancer vaccine
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533:left ventricular assist device, the world's first
883:
881:
360:Norton Hospital & Norton Healthcare Pavilion
1814:University of Louisville Cardinal Marching Band
1402:"First local heart transplant was 30 years ago"
915:"University of Louisville Best Medical Schools"
265:University of Louisville Health Sciences Campus
1105:. Grad-schools.usnews.rankingsandreviews.com.
1964:
1540:
1009:: University Press of Kentucky. p. 561.
954:: University Press of Kentucky. p. 604.
8:
2226:Educational institutions established in 1837
2064:Louisville Presbyterian Theological Seminary
772:. University of Louisville. March 23, 2015.
21:
1077:"University of Louisville College Portrait"
270:University of Louisville Medical Department
184:University of Louisville School of Medicine
1971:
1957:
1949:
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1533:
1525:
20:
16:Medical school in Louisville, Kentucky, US
2054:Jefferson Community and Technical College
1269:
654:African Americans make up 7% of the class
635:The entering Class of 2013 consisted of:
461:National Heart, Lung, and Blood Institute
420:Learn how and when to remove this message
852:Altman, Lawrence K. (January 26, 1999).
795:
793:
791:
645:63 Colleges and Universities represented
260:
2241:Local landmarks in Louisville, Kentucky
2079:Purdue University College of Technology
1438:from the original on September 24, 2015
1109:from the original on September 27, 2012
761:
692:List of University of Louisville people
244:United States Secretary of the Treasury
1295:
1285:
1217:from the original on December 21, 2013
1083:from the original on September 3, 2012
602:Memorial Sloan-Kettering Cancer Center
2089:Southern Baptist Theological Seminary
2049:Ivy Tech Community College of Indiana
1324:from the original on October 17, 2020
1236:The Lancet Editors (March 16, 2019).
1165:from the original on January 22, 2021
833:from the original on October 18, 2015
776:from the original on January 10, 2018
7:
1930:
1749:L&N Federal Credit Union Stadium
819:Altman, Lawrence K. (July 4, 2001).
402:adding citations to reliable sources
258:southern and western United States.
1031:from the original on March 13, 2023
976:from the original on March 13, 2023
1381:from the original on July 29, 2013
1057:from the original on July 26, 2013
866:from the original on June 13, 2018
451:that could protect the heart from
14:
1464:from the original on May 18, 2024
1412:from the original on May 18, 2024
1355:from the original on May 18, 2024
921:from the original on May 23, 2013
339:University of Louisville Hospital
2162:
2108:College of Technology and Design
1929:
1916:
1915:
378:
342:James Graham Brown Cancer Center
29:
2231:1837 establishments in Kentucky
2034:Indiana Institute of Technology
1458:"School of Medicine Statistics"
495:, first reported repair of the
389:needs additional citations for
1002:The Encyclopedia of Louisville
997:"Louisville Medical Institute"
947:The Encyclopedia of Louisville
736:Dorothy 'Dot' Richardson, M.D.
365:VA Medical Center – Louisville
1:
1254:10.1016/S0140-6736(19)30542-2
940:Papangelis, Penelope (2001).
889:"HSC Master Plan: Background"
802:Filson Club History Quarterly
465:National Institutes of Health
2039:Indiana University Southeast
1988:Louisville metropolitan area
1616:Louisville Municipal College
1213:. University of Louisville.
999:. In Kleber, John E. (ed.).
944:. In Kleber, John E. (ed.).
741:Raymond L. Woosley Jr., M.D.
238:Louisville Medical Institute
224:U.S. News & World Report
208:Louisville Medical Institute
51:; 187 years ago
2221:Medical schools in Kentucky
2126:Speed School of Engineering
2044:Indiana Wesleyan University
1807:Kentucky–Louisville rivalry
2257:
1641:William F. Ekstrom Library
689:
544:remodeling in the region.
457:American Heart Association
453:ischemic myocardial damage
356:Norton Children's Hospital
2158:
2014:Campbellsville University
1994:
1910:
1564:
632:and/or ties to Kentucky.
621:National Cancer Institute
28:
2236:University of Louisville
2118:University of Louisville
2059:Louisville Bible College
2029:Galen College of Nursing
1557:University of Louisville
1079:. Collegeportraits.org.
188:University of Louisville
144:Red, Black, Yellow, Gray
70:University of Louisville
22:University of Louisville
2197:38.248389°N 85.748500°W
1879:The Louisville Cardinal
770:"Primary Color Palette"
523:cardiothoracic surgeons
217:, the first successful
2130:Brandeis School of Law
1432:"AbioCor Implantation"
731:Maurice Rabb Jr., M.D.
538:saphenous vein harvest
320:Health Sciences Center
314:Health Sciences Center
266:
2202:38.248389; -85.748500
2140:University of Phoenix
2004:Bellarmine University
1860:University presidents
1821:U of L Sports Network
1705:Jim Patterson Stadium
1318:Antelope Valley Press
281:Charles Wilkins Short
264:
2074:Northwood University
2009:Brown Mackie College
1676:Confederate monument
1572:Louisville, Kentucky
1320:. October 14, 2020.
995:Cox, Dwayne (2001).
725:Judith Ann Pachciarz
714:C. Ronald Kahn, M.D.
651:60% male, 40% female
512:free tissue transfer
476:Circulation Research
398:improve this article
300:Grace Marilynn James
298:In the early 1950s,
293:David Wendel Yandell
2193: /
2169:Kentucky portal
2122:College of Business
2104:Sullivan University
2099:Spalding University
1406:The Courier-Journal
1190:The Courier-Journal
1135:on November 3, 2014
1007:Lexington, Kentucky
952:Lexington, Kentucky
895:on November 3, 2014
746:James Henry Wayland
703:Anthony Atala, M.D.
25:
2145:Webster University
2134:School of Medicine
2112:Spencerian College
1894:Collegiate Chorale
1494:on August 30, 2009
1434:. Heart Pioneers.
1400:Schneider, Grace.
1298:has generic name (
859:The New York Times
826:The New York Times
672:Fitzbutler College
503:repair, and first
267:
92:Jeffrey M. Bumpous
65:Parent institution
24:School of Medicine
2176:
2175:
1946:
1945:
1655:Moore Observatory
1488:www2.hu-berlin.de
1184:Watkins, Morgan.
1129:"HSC Master Plan"
942:"Medical Schools"
698:Irvin Abell, M.D.
430:
429:
422:
351:Norton Healthcare
289:Benjamin Silliman
285:J. Lawrence Smith
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2069:National College
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1518:Official website
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1490:. Archived from
1484:"Advisory Board"
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891:. Archived from
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719:Jennifer A. Koch
527:heart transplant
497:digital arteries
489:hand transplants
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215:artificial heart
206:. Opened as the
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2084:Simmons College
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1343:Boyett, Frank.
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1248:(10176): 1084.
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1211:"Roberto Bolli"
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681:Pickett College
678:Yandell College
629:
439:autotransfusion
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1777:Lynn Stadium
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1595:Engineering
1498:January 12,
1349:The Gleaner
542:ventricular
410:August 2015
370:Innovations
335:UofL Health
194:located in
46:Established
2215:Categories
1793:Ice hockey
1713:Basketball
1567:Located in
1242:The Lancet
757:References
690:See also:
535:endoscopic
508:epiphyseal
470:The Lancet
196:Louisville
170:louisville
112:Louisville
1688:Athletics
1416:March 24,
1359:March 24,
1328:March 25,
1262:0140-6736
1195:March 24,
1169:March 24,
1035:August 9,
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780:March 23,
591:reported.
174:/medicine
94:(interim)
77:Endowment
1984:colleges
1922:Category
1853:Athletes
1786:Softball
1742:Football
1698:Baseball
1634:Campuses
1609:Medicine
1588:Business
1468:June 15,
1462:Archived
1436:Archived
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1107:Archived
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627:Students
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481:comments
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200:Kentucky
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107:Location
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