464:(EPR) to study enzyme mechanisms. He published over 400 papers and at least an additional 50 book chapters, symposia or reviews, for example on artificial flavins as mechanistic probes. He also had a significant mentoring role; his students included Graham Palmer, Charles H. Williams,
393:), for example a study of the effects of temperature. However, Massey was exposed to flavins in the lab through working with other students. After completing his thesis, he moved to the United States for a summer to work with
369:
After obtaining a B.S. in biochemistry from the
University of Sydney, Massey worked as a research biochemist for the CSIRO. He worked there for three years, and in that time published five papers on the inhibition of the
853:
Alberty, Robert A.; Massey, Vincent; Frieden, Carl; Fuhlbrigge, Armin R. (1954). "Studies of the Enzyme
Fumarase. III.1 the Dependence of the Kinetic Constants at 25° upon the Concentration and pH of Phosphate Buffers".
338:. Massey became interested in science in high school, to the point of performing home chemistry experiments. He was the first in his family to go to university and he obtained a Bachelor of Science from the
1310:
354:
1305:
1144:
Macheroux, Peter; Mulrooney, Scott B.; Williams, Charles H.; Massey, Vincent (1992). "Direct expression of active spinach glycolate oxidase in
Escherichia coli".
438:
in the
Biochemistry Department. By 1961, he was promoted to senior lecturer. In 1963, Massey changed his career path and took a professorship position the
1300:
378:
by fluoroacetate. The CSIRO awarded him with a fellowship that would allow him to pursue his doctoral degree at the
University of Cambridge.
446:. Massey was awarded the Henry Russel Lectureship in 1995, the highest recognition given to faculty members at the University of Michigan.
1295:
461:
398:
965:
Brissette, Pierre; Ballou, David P.; Massey, Vincent (1989). "Determination of the dead time of a stopped-flow fluorometer".
263:
889:
Singer, Thomas P.; Kearney, Edna B.; Massey, Vincent (1956). "Observations on the flavin moiety of succinic dehydrogenase".
727:
571:
310:
153:
424:
401:. Here, he continued studying fumarase and published in 1954 possibly the first thorough paper studying steady-state
382:
335:
234:
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44:
435:
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358:
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145:
101:
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768:
339:
93:
469:
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871:
244:
1261:
1212:
1171:
1126:
1082:
1033:
992:
947:
906:
835:
786:
705:
665:
449:
His major scientific contributions include the identification and kinetic characterization of
394:
926:"Production of a covalent flavin linkage in lipoamide dehydrogenase - reaction with 8-Cl-FAD"
1251:
1243:
1202:
1161:
1153:
1116:
1072:
1064:
1023:
982:
974:
937:
898:
863:
825:
817:
776:
697:
655:
229:
688:
Ballou, David P; Williams, Charles H; Coon, Minor J (2002). "Vincent Massey (1926–2002)".
402:
309:
best known for his contributions to the study of flavoenzymes. Massey was elected to the
48:
1012:"Electron paramagnetic resonance and circular dichroism studies on milk xanthine oxidase"
772:
1256:
1231:
1077:
1052:
830:
805:
541:
Biomedical
Research Council Distinguished Faculty Lectureship, University of Michigan
509:
136:
1207:
1190:
1121:
1104:
1028:
1011:
942:
925:
701:
517:
University of
Konstanz, Fachbereich Biologie, Konstanz, West Germany, Guest Professor
357:(CSIRO) as a research biochemist. They married during his time there and left for the
1279:
1157:
978:
902:
875:
453:
428:
350:
473:
457:
390:
343:
314:
248:
1053:"New flavins for old - artificial flavins as active-site probes of flavoproteins"
427:
was covalently bound to the enzyme. This started Massey's career on flavins and
361:
in 1950, never returning to
Australia. Vincent and his wife had three children.
306:
302:
177:
709:
669:
450:
443:
371:
80:
1232:"Green butyryl-coenzyme a dehydrogenase. An enzyme–acyl-coenzyme a complex"
910:
839:
790:
660:
643:
1265:
1216:
1175:
1130:
1086:
1037:
996:
1166:
987:
951:
386:
375:
867:
592:
Jubilee
Lecture and Harden Medal, Biochemical Society of Great Britain
559:
Visiting
Professor, Yokohama City University School of Medicine, Japan
412:
A colleague from Cambridge, Tom Singer, had accepted a position at the
1247:
1068:
821:
330:
Massey grew up in a family of fishermen in a small village outside of
781:
756:
417:
213:
553:
Visiting Professor Institute of Applied Biochemistry, Mitake, Japan
547:
Distinguished Faculty Achievement Award, The University of Michigan
416:
in Detroit and recruited Massey to work with him to investigate the
1146:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
644:"Vincent Massey 28 November 1926 - 26 August 2002 Elected FRS 1977"
497:
Teacher, Marine Biological Laboratory, Woods Hole, Massachusetts
523:
Permanent Guest Professor, University of Konstanz, West Germany
476:, and Paul Engel on butyryl-CoA dehydrogenase, among others.
1191:"Isolation of old yellow enzyme in free and complexed forms"
434:
In 1957, Massey returned to England to be a lecturer at the
355:
Commonwealth Scientific and Industrial Research Organisation
406:
580:
J. Lawrence Oncley Distinguished University Professorship
301:(November 28, 1926 – August 26, 2002) was an Australian
313:
in 1995 for his use of physical biochemistry to relate
1103:
Olson, J S; Ballou, D P; Palmer, G; Massey, V (1974).
1311:
Burials at Forest Hill Cemetery (Ann Arbor, Michigan)
1105:"Reaction of xanthine-oxidase with molecular-oxygen"
757:"The Tricarboxylic Acid Cycle in Nematode Parasites"
683:
681:
679:
648:
Biographical Memoirs of Fellows of the Royal Society
806:"Studies on fumarase. 3. The effect of temperature"
726:Ballou, David P.; Williams Jr., Charles H. (2013).
258:
240:
228:
212:
183:
173:
129:
121:
113:
86:
76:
68:
56:
30:
23:
353:, while he was working at a government laboratory
385:. His thesis project revolved around the enzyme
565:Henry Russel Lecturer University of Michigan
8:
924:Moore, E G; Cardemil, E; Massey, V (1978).
529:Senior Fellow, Michigan Society of Fellows
535:Elected Fellow of Royal Society of London
20:
1255:
1206:
1165:
1120:
1076:
1027:
986:
941:
829:
780:
659:
72:Forest Hill Cemetery, Ann Arbor, Michigan
1306:Academics of the University of Sheffield
1098:
1096:
856:Journal of the American Chemical Society
721:
719:
891:Archives of Biochemistry and Biophysics
755:Massey, Vincent; Rogers, W. P. (1949).
642:Williams, C. H.; Ballou, D. P. (2003).
605:
491:Guest Lecturer, University of Illinois
485:I.C.I. Fellow, University of Cambridge
423:. Singer had recently discovered that
349:He met his wife Margot, a survivor of
16:Australian biochemist and enzymologist
611:
609:
7:
1230:Engel, Paul C.; Massey, V. (1971).
14:
1189:Matthews, R G; Massey, V (1969).
381:Massey did his thesis work with
317:chemistry to flavin enzymology.
219:Studies on the Enzyme, Fumarase
586:Michigan Scientist of the Year
462:electron paramagnetic resonance
399:University of Wisconsin-Madison
1301:University of Michigan faculty
690:Trends in Biochemical Sciences
623:. National Academy of Sciences
456:and pioneering the methods of
405:of an enzyme as a function of
190:McMaster Laboratory C.S.I.R.O.
1:
1208:10.1016/S0021-9258(18)91750-3
1122:10.1016/S0021-9258(19)42427-7
1051:Ghisla, S; Massey, V (1986).
1029:10.1016/S0021-9258(18)83444-5
1010:Palmer, G; Massey, V (1969).
943:10.1016/S0021-9258(19)46948-2
702:10.1016/S0968-0004(02)02222-3
1158:10.1016/0167-4781(92)90046-3
979:10.1016/0003-2697(89)90235-2
903:10.1016/0003-9861(56)90415-5
621:National Academy of Sciences
572:National Academy of Sciences
311:National Academy of Sciences
154:National Academy of Sciences
1327:
336:New South Wales, Australia
204:The University of Michigan
254:
166:
967:Analytical Biochemistry
480:Scientific achievements
472:("old yellow enzyme"),
436:University of Sheffield
421:succinate dehydrogenase
359:University of Cambridge
199:University of Sheffield
146:Royal Society of London
102:University of Cambridge
1296:Australian biochemists
661:10.1098/rsbm.2003.0019
440:University of Michigan
574:Member, Biochemistry
156:Member, Biochemistry
735:Biographical Memoirs
340:University of Sydney
94:University of Sydney
1236:Biochemical Journal
868:10.1021/ja01638a053
810:Biochemical Journal
804:Massey, V. (1953).
773:1949Natur.163..909M
470:NADPH dehydrogenase
414:Henry Ford Hospital
194:Henry Ford Hospital
503:A.S.B.C. Lecturer
466:Rowena G. Matthews
245:Rowena G. Matthews
144:Elected Fellow of
1248:10.1042/bj1250889
1115:(14): 4350–4362.
1069:10.1042/bj2390001
1022:(10): 2614–2620.
936:(18): 6413–6422.
822:10.1042/bj0530072
595:
589:
583:
577:
568:
562:
556:
550:
544:
538:
532:
526:
520:
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506:
500:
494:
488:
460:and rapid-freeze
395:Robert A. Alberty
296:
295:
241:Doctoral students
168:Scientific career
159:
150:
141:
117:Flavin Enzymology
41:November 28, 1926
1318:
1270:
1269:
1259:
1227:
1221:
1220:
1210:
1201:(7): 1779–1786.
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1180:
1179:
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1124:
1100:
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1080:
1048:
1042:
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1031:
1007:
1001:
1000:
990:
962:
956:
955:
945:
921:
915:
914:
886:
880:
879:
862:(9): 2485–2493.
850:
844:
843:
833:
801:
795:
794:
784:
782:10.1038/163909a0
752:
746:
745:
743:
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732:
728:"Vincent Massey"
723:
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685:
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617:"Vincent Massey"
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230:Doctoral advisor
224:
157:
148:
139:
125:Margot Grünewald
106:
98:
63:
40:
38:
21:
1326:
1325:
1321:
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803:
802:
798:
754:
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739:
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724:
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696:(12): 641–642.
687:
686:
677:
641:
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636:
626:
624:
615:
614:
607:
602:
482:
474:David P. Ballou
367:
365:Academic career
328:
323:
272:/20160304142132
262:
222:
208:
162:
109:
104:
96:
87:Alma mater
61:
60:August 26, 2002
52:
49:New South Wales
42:
36:
34:
26:
17:
12:
11:
5:
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1308:
1303:
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1272:
1271:
1242:(3): 889–902.
1222:
1181:
1136:
1092:
1043:
1002:
973:(2): 234–238.
957:
916:
897:(1): 255–257.
881:
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510:Humboldt Award
507:
501:
495:
489:
481:
478:
366:
363:
327:
324:
322:
319:
299:Vincent Massey
294:
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137:Humboldt Award
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114:Known for
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66:
65:
64:(aged 75)
58:
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32:
28:
27:
25:Vincent Massey
24:
15:
13:
10:
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6:
4:
3:
2:
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1195:J. Biol. Chem
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1167:2027.42/29898
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1109:J. Biol. Chem
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1016:J. Biol. Chem
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988:2027.42/27776
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930:J. Biol. Chem
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811:
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767:(4154): 909.
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729:
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455:
454:dehydrogenase
452:
447:
445:
441:
437:
432:
430:
429:flavoproteins
426:
422:
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388:
384:
383:Malcolm Dixon
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351:the Holocaust
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235:Malcolm Dixon
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105:(Ph.D., 1953)
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100:
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69:Resting place
67:
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50:
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1152:(1): 11–16.
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816:(1): 72–79.
813:
809:
799:
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750:
738:. Retrieved
734:
693:
689:
651:
647:
637:
625:. Retrieved
620:
458:stopped-flow
448:
433:
411:
391:flavoprotein
380:
368:
348:
344:biochemistry
329:
307:enzymologist
298:
297:
249:David Ballou
218:
184:Institutions
167:
97:(B.S., 1947)
62:(2002-08-26)
18:
1291:2002 deaths
1286:1926 births
1063:(1): 1–12.
740:February 1,
654:: 335–350.
627:February 1,
531:(1975-1980)
519:(1973-1974)
487:(1953-1955)
326:Family life
77:Nationality
51:, Australia
1280:Categories
1057:Biochem. J
600:References
303:biochemist
178:Enzymology
81:Australian
37:1926-11-28
876:100746202
710:0968-0004
670:0080-4606
451:lipoamide
444:Ann Arbor
376:nematodes
372:TCA cycle
346:in 1947.
321:Biography
911:13283607
840:13032036
791:18131520
582:(1995- )
525:(1975- )
403:kinetics
387:fumarase
332:Berkeley
284:/~graham
266:.archive
45:Berkeley
1266:5145911
1257:1178195
1217:4388613
1176:1324737
1131:4367214
1087:3541919
1078:1147232
1038:4306032
997:2510550
831:1198105
769:Bibcode
397:at the
389:(not a
286:/Massey
259:Website
1264:
1254:
1215:
1174:
1129:
1085:
1075:
1036:
995:
952:681358
950:
909:
874:
838:
828:
789:
761:Nature
708:
668:
594:(1999)
588:(1998)
576:(1995)
567:(1995)
561:(1988)
555:(1985)
549:(1983)
543:(1979)
537:(1977)
513:(1973)
505:(1963)
499:(1962)
493:(1960)
418:enzyme
315:flavin
274:/http:
223:(1953)
221:
214:Thesis
174:Fields
158:(1995)
149:(1977)
140:(1973)
130:Awards
122:Spouse
872:S2CID
731:(PDF)
468:, on
290:.html
280:.rice
278:.bioc
276://www
1262:PMID
1213:PMID
1172:PMID
1150:1132
1127:PMID
1083:PMID
1034:PMID
993:PMID
948:PMID
907:PMID
836:PMID
787:PMID
742:2015
706:ISSN
666:ISSN
629:2015
305:and
282:.edu
270:/web
268:.org
57:Died
31:Born
1252:PMC
1244:doi
1240:125
1203:doi
1199:244
1162:hdl
1154:doi
1117:doi
1113:249
1073:PMC
1065:doi
1061:239
1024:doi
1020:244
983:hdl
975:doi
971:181
938:doi
934:253
899:doi
864:doi
826:PMC
818:doi
777:doi
765:163
698:doi
656:doi
442:in
425:FAD
374:in
342:in
334:in
288:/VM
264:web
1282::
1260:.
1250:.
1238:.
1234:.
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1197:.
1193:.
1170:.
1160:.
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1125:.
1111:.
1107:.
1095:^
1081:.
1071:.
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1055:.
1032:.
1018:.
1014:.
991:.
981:.
969:.
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932:.
928:.
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895:60
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870:.
860:76
858:.
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814:53
812:.
808:.
785:.
775:.
763:.
759:.
733:.
718:^
704:.
694:27
692:.
678:^
664:.
652:49
650:.
646:.
619:.
608:^
431:.
409:.
407:pH
247:,
47:,
1268:.
1246::
1219:.
1205::
1178:.
1164::
1156::
1133:.
1119::
1089:.
1067::
1040:.
1026::
999:.
985::
977::
954:.
940::
913:.
901::
878:.
866::
842:.
820::
793:.
779::
771::
744:.
712:.
700::
672:.
658::
631:.
39:)
35:(
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