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Wyatt Technology Corporation

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86:’s earlier venture, Science Spectrum, Inc. (SSI), which was founded in 1968 to investigate the characterization of bacteria using light scattering. Wyatt used a breadboard instrument developed at SSI to confirm that light scattering could reveal bacterial effects that are not observable with a microscope. Further studies explored the efficacy of antibiotic agents on bacteria. A commercial instrument, the Differential I, was ultimately developed in an attempt to provide convenient and accurate data while still maintaining flexibility necessary in exploring this new field. In order to better test antibiotic susceptibility, SSI developed the Differential III which was one of the first analytical instruments to incorporate an onboard computer and utilized the first batch run of Intel’s 8008 chips. Although SSI attracted several clients and was awarded several U.S. Government contracts, cash flow problems ultimately led to its collapse. 117:
better,” and how this type of analysis might be used to aid producers in emulating successful drinks by analyzing and attempting to reproduce their light scattering patterns. In 1983 Ballard Canyon Winery, located in Solvang, California, produced a “Laser Certified” cabernet sauvignon. The label displayed a laser fingerprint and values including a Body score of 447 and a Structure of 218, and stated, “We believe this unique laser fingerprint will provide a reference standard of this fine wine for many years to come and permit, thereby, an objective comparison with other vintages.”
145:(SBIR) contracts involving the rapid detection of contaminants in water and air spurred the growth of the company which was incorporated as Wyatt Technology Corporation in 1984. Wyatt proceeded to develop batch light scattering instruments (DAWN-B) that made measurements from samples contained within scintillation vials as well as flow through instruments (DAWN-F) for use in conjunction with high performance liquid chromatography (HPLC). In the late 1980s Wyatt purchased the Optilab line of interferometric refractometers from the Swedish company Tekator. 196:
Editor's Silver award, and was also named, by R&D Magazine, one of the top 100 innovative new products of the year. At Pittcon in 2017 Wyatt's HELEOS II MALS detector won Select Science's Reviewers’ Choice Award for Instrument of the Year. In 2013 Wyatt's Optialb UT-rEX was awarded the Innovation
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and newspaper articles across the country with titles such as "Grape Nuts! No Loser with Laser," by New York Daily News science editor Edward Edelson, and "A Curvy Little wine." Wyatt followed up this successful article with a paper in Applied Optics entitled “A Taste of Things to Come,” in which he
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As he wrapped up the business of the company, Wyatt published a letter in Science recounting light scattering patterns of various wines analyzed with the Differential III and correlated the scattering patterns to price and the opinions of the quality of the wine by a panel of local wine enthusiasts.
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instruments in the world. Its instruments are used by about 30,000 scientists worldwide, data from the use of their instruments has been published in over 12,000 peer reviewed articles, and have been used in the research of several Nobel Laureates. Wyatt Technology, its founder, and its instruments
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In the mid 1990s the burgeoning pharmaceutical industry showed interest in using DAWN instruments coupled with HPLC to measure the molecular weight of proteins, widening the scope of utility of Wyatt instruments which had, up to that time, been primarily used for the characterization of synthetic
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whose article “No Accounting” explained to the lay person just how Wyatt's light scattering experiments worked and how they were being used to classify not only wine but cola drinks as well, and questioned how far this kind of testing could go in determining which competing brand actually “tasted
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Wyatt formed Wyatt Technology Company in 1981 in order to wrap up uncompleted government research contracts as interest in his Science letter continued. National interest in wine fingerprinting and media reports on the Applied Optics cola studies ultimately garnered the attention of
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Award by “The Analytical Scientist” magazine as was the μDAWN in 2014. Wyatt Technology has also been awarded several local business awards including the South Coast Business and Technology Award as “Company of the Year” in 2009 and the Spirit of Small Business award in 2004.
186:’s prize for “Industrial Applications of Physics” for pioneering developments in the inverse scattering problem as well successful and sustained commercialization of analytical instrumentation. Wyatt Technology has been named one of the “Best Places to Work in Industry” by 154:
polymers. In 2004 Wyatt Technology acquired the DynaPro line of dynamic light scattering instruments from bankrupt Proterion. Since this time Wyatt Technology has modernized its instruments into a full line of state-of-the-art particle and molecular characterization tools.
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in 2011 in recognition visible technological impact on the socio-economic front. Winners of the “Tibbie” exemplify the very best in SBIR achievements. Founder, Philip Wyatt, was granted the
125:, who engaged the newly founded Wyatt Technology Company and awarded them a contract to study various attributes pertaining to their beverages. The wine studies also caught the attention of 165:, an American analytical laboratory instrument and software company, agreed to acquire Wyatt Technology for $ 1.36 billion in cash in February 2023. The acquisition completed in May 2023. 661: 776: 489: 781: 173:
Wyatt Technology is largely notable as a SBIR success story. Begun primarily with SBIR grants, Wyatt Technology has grown to be the largest supplier of
46:, Wyatt Technology was founded in 1981 and incorporated in 1984. Wyatt Technology has developed and introduced instrumentation for the measurement of 580: 771: 62:, and composition gradient multiangle light scattering (CG-MALS) for the determination of absolute molecular weights, sizes of nanoparticles, 606: 142: 137:
As a result, Wyatt Technology developed the first in its line of DAWN (originally an acronym for “Dual Angle Weighted Nephelometry”)
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Wyatt, Philip J. (1970). "Cell Wall Thickness, Size Distribution, Refractive Index Ratio and Dry Weight Content of Living Bacteria (
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This article drew national attention from various media outlets including an write up in the popular scientific magazine
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magazine from 2008-2013. Wyatt Technology's Optilab rEX differential refractometer was awarded the 2004
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Wyatt, Philip J. (1969). "Identification of Bacteria by Differential Light Scattering".
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have received many awards from the scientific and business communities, including the
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Wyatt, Geofrey K. (1984). "A Bit of Revolution in Scientific Instrumentation".
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is a developer and manufacturer of instrumentation for the characterization of
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Expansion into the pharmaceutical and protein markets and DynaPro acquisition
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Phillips, David T. (1971). "Evolution of a Light Scattering Photometer".
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instruments. Continuing interest in the DAWN instruments as well as
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Thomsen, D.E. (December 3, 1983). "Wine-tasting in Vitro".
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reported similar studies on popular cola drinks such as
607:"The Scientist Best Places to Work in Industry 2013" 414:Wyatt, P.J. (1982). "The Taste of Things to Come". 630: 628: 336: 334: 332: 330: 82:Wyatt Technology arose from the ashes of founder 441:Asimov, Isaac (November 1983). "No Accounting". 364:Wyatt, P. J. (1981). "Days of Wine and Lasers". 343:"Instrument Maker Wyatt Charts Its Own Course" 662:"Scientists' Choice Awards Winners Announced" 581:"American Physical Society Prizes and Awards" 8: 777:Companies based in Santa Barbara, California 782:Technology companies based in California 555:"About Tibbetts Awards and Hall of Fame" 90:Wine, Coca-Cola and the company founding 206: 54:(DLS)), differential refractive index, 746:. Santa Barbara Scholarship Foundation 317:Analytical Instruments & Computers 70:within a solution. It was acquired by 7: 474:Mathews, Eva (February 15, 2023). 143:Small Business Innovation Research 25: 457:"Wyatt Technology - Our History" 514:. Wyatt Technology Corporation. 508:"Wyatt Technology Bibliography" 463:. Wyatt Technology Corporation. 496:(Press release). May 16, 2023. 1: 772:2023 mergers and acquisitions 378:10.1126/science.212.4500.1212 347:Chemical and Engineering News 28:Wyatt Technology Corporation, 587:. American Physical Society 175:multiangle light scattering 139:multiangle light scattering 48:multiangle light scattering 798: 720:. The Analytical Scientist 694:. The Analytical Scientist 561:. United States Government 535:. United States Government 158:Sale to Waters Corporation 184:American Physical Society 44:Santa Barbara, California 718:The Analytical Scientist 692:The Analytical Scientist 613:. The Scientist Magazine 52:dynamic light scattering 526:"The Best in SBIR 2011" 714:"Return of the TASIAs" 341:Reisch, M. S. (2013). 127:S.C. Johnson & Son 688:"The TASIAs are here" 286:Staphylococcus aureus 123:the Coca-Cola Company 428:10.1364/AO.21.002471 372:(4500): 1212–1214. 257:(5187): 1257–1258. 133:New instrumentation 42:. Headquartered in 494:Cision PR Newswire 163:Waters Corporation 72:Waters Corporation 744:SBScholarship.org 642:. Chemical Online 611:The-Scientist.com 422:(14): 2471–2472. 296:(5242): 277–279. 263:10.1038/2211257a0 32:Wyatt Technology, 16:(Redirected from 789: 756: 755: 753: 751: 736: 730: 729: 727: 725: 710: 704: 703: 701: 699: 684: 678: 677: 675: 673: 668:. 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Wyatt 80: 56:electrophoresis 23: 22: 15: 12: 11: 5: 795: 793: 785: 784: 779: 774: 764: 763: 758: 757: 731: 705: 679: 653: 640:ChemicalOnline 624: 598: 572: 546: 517: 499: 481: 466: 448: 433: 416:Applied Optics 406: 391: 356: 326: 307: 276: 241: 205: 204: 202: 199: 180:Tibbetts Award 170: 167: 159: 156: 150: 147: 134: 131: 91: 88: 79: 76: 40:macromolecules 24: 14: 13: 10: 9: 6: 4: 3: 2: 794: 783: 780: 778: 775: 773: 770: 769: 767: 745: 741: 735: 732: 719: 715: 709: 706: 693: 689: 683: 680: 667: 666:ScienceSelect 663: 657: 654: 641: 637: 631: 629: 625: 612: 608: 602: 599: 586: 582: 576: 573: 560: 556: 550: 547: 534: 527: 521: 518: 513: 509: 503: 500: 495: 491: 485: 482: 477: 470: 467: 462: 458: 452: 449: 444: 437: 434: 429: 425: 421: 417: 410: 407: 402: 395: 392: 387: 383: 379: 375: 371: 367: 360: 357: 352: 348: 344: 337: 335: 333: 331: 327: 322: 318: 311: 308: 303: 299: 295: 291: 287: 280: 277: 272: 268: 264: 260: 256: 252: 245: 242: 237: 233: 229: 225: 221: 217: 210: 207: 200: 198: 195: 191: 190: 189:The Scientist 185: 181: 176: 168: 166: 164: 157: 155: 148: 146: 144: 140: 132: 130: 128: 124: 118: 115: 111: 107: 103: 98: 89: 87: 85: 77: 75: 73: 69: 65: 61: 57: 53: 49: 45: 41: 37: 36:nanoparticles 33: 29: 19: 748:. 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Reuters. 216:BioScience 201:References 512:wyatt.com 461:wyatt.com 169:Accolades 108:Cola and 102:Coca-Cola 74:in 2023. 60:viscosity 750:16 March 724:16 March 698:16 March 672:16 March 646:16 March 617:16 March 591:16 March 565:16 March 539:16 March 445:: 25–27. 386:17738815 68:polymers 64:proteins 585:aps.org 366:Science 271:4886590 236:1295813 194:Pittcon 110:RC Cola 78:History 403:: 365. 384:  290:Nature 269:  251:Nature 234:  66:, and 529:(PDF) 232:JSTOR 106:Pepsi 752:2017 726:2017 700:2017 674:2017 648:2017 619:2017 593:2017 567:2017 559:SBIR 541:2017 533:SBIR 382:PMID 288:)". 267:PMID 38:and 424:doi 374:doi 370:212 298:doi 294:226 259:doi 255:221 224:doi 58:, 30:or 768:: 742:. 716:. 690:. 664:. 638:. 627:^ 609:. 583:. 557:. 531:. 510:. 492:. 459:. 420:21 418:. 380:. 368:. 351:91 349:. 345:. 329:^ 319:. 292:. 265:. 253:. 230:. 220:21 218:. 104:, 754:. 728:. 702:. 676:. 650:. 621:. 595:. 569:. 543:. 430:. 426:: 388:. 376:: 321:1 304:. 300:: 273:. 261:: 238:. 226:: 20:)

Index

Wyatt Technology
nanoparticles
macromolecules
Santa Barbara, California
multiangle light scattering
dynamic light scattering
electrophoresis
viscosity
proteins
polymers
Waters Corporation
Philip J. Wyatt
Science News
Coca-Cola
Pepsi
RC Cola
Isaac Asimov
the Coca-Cola Company
S.C. Johnson & Son
multiangle light scattering
Small Business Innovation Research
Waters Corporation
multiangle light scattering
Tibbetts Award
American Physical Society
The Scientist
Pittcon
doi
10.2307/1295813
JSTOR

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