950:" refers to the number of new cases per unit population per unit time (usually per year). However postpartum disease frequencies should be described as the number of cases divided by the number of pregnancies. Incidence is not an appropriate way of describing the frequency of cases of postpartum diseases. Similarly, "the general population" is not an appropriate population group for postpartum diseases. (Does the group include men, elderly women, etc.?)
331:
abnormalities in erectile dysfunction, not for an article on hypothyroidism. The second source would be suitable for an article about anaemia in hypothyroidism. Knowledge's article on "Hypothyroidism" is supposed to be a general encyclopedic article, not an exhaustive treatise on all aspects of hypothyroidism.
1068:
A minor point: the journal references have inconsistent formatting. Some journals are abbreviated without full stops (e.g. 3: Brown, 8: Gaitonde), some with full stops (e.g. 7: Vissenberg, 9: Persani), some in full with upper case (e.g. 5: Klubo-Gwiezdzinska, 6: van den
Boogaard) and some with lower
273:
You could do that, but I don't think that is a good approach. Currently, the section is an amalgamation of information from nine different sources. I think that readers are better served by a table of features all sourced from one single reference such as an authoritative endocrinology textbook. This
352:
With endocrinology textbooks or review articles about hypothyroidism, the author/editor is an expert and has already decided on appropriate weighting for the various causes. Different sources may have discrepancies between the exact list, so it may be necessary to choose a source that you think best
330:
This article is about "Hypothyroidism". Its references should be generically about hypothyroidism, not focussed on specific aspects, especially in the "Signs and symptoms" section. This prevents issues of undue weighting. For example, the first source would be suitable for an article about hormonal
715:
I knew it was a long sentence, but I wrote it when I was tired =( and wasn't sure how to rearrange it. I think the revised version is a definite improvement. Thanks Axl. I don't think we should assume all readers know estrogen levels go up during pregnancy (granted, most would and more importantly
527:
Rewritten in what way? In prose format? You suggested a table before and I see you suggested doing it from one single authoritative source such as an endocrinology textbook (I don't own any), so if you have access to such a source, feel free to rearrange as you see fit. I think it's best to have a
628:
I've got the 17th, so let me know when you're ready to make the table and I'll work on it with you. The 17th has a table (probably the same or similar) listing signs/symptoms in descending order of frequency. I cleaned up that section a little bit (not in a table yet) and reordered things to some
245:
Numerous signs and symptoms are associated with hypothyroidism, and can relate to the underlying pathological cause of the hypothyroidism, a mass effect of a thyroid goiter, or direct effects of having insufficient thyroid
905:
I like it, let's make that happen in the article. Wouldn't menorrhagia be a sign though since it can be objectively measured in terms of how many days/blood lost with defined parameters for what constitutes menorrhagia?
528:
variety of sources since I doubt any one particular source will list off all of the numerous signs/symptoms of hypothyroidism-most review articles didn't have them all and omitted some well-known ones.
153:
I've listed this article for peer review because I am working on getting it to GA status and need feedback to make any necessary improvements. Constructive criticism and suggestions are welcomed.
669:
During pregnancy, iodine requirements are higher as there is an increased demand for thyroid hormones due to decreased levels of free thyroid hormone secondary to elevated circulating levels of
1418:
Maggi M, Buvat J, Corona G, Guay A, Torres LO (March 2013). "Hormonal causes of male sexual dysfunctions and their management (hyperprolactinemia, thyroid disorders, GH disorders, and DHEA)".
197:
I'm sure it does have other autoimmune causes. I will look into it and have other autoimmune diseases used as examples so the article is not repetitive and harping on the
Hashimoto's point.
665:
this sentence goes on forever; by the time I get to the end of all of those clauses, I forget what it's trying to say. Are you able to fix it? I tried, and the result was worse.
677:
I think it's backwards; the reader knows estrogen levels increase during pregnancy, so the sentence would be easier to get through if it started there rather than ending there.
944:
Hypothyroidism can result from postpartum thyroiditis up to nine months after giving birth.... This condition has an incidence of about 5% in the general population.
1400:
1353:
560:
I have access to
Williams Textbook of Endocrinology 12th edition. It has an excellent table of causes. However the clinical findings are described in text form.
316:
I'd like more opinions on that. I don't see how these are inappropriate sources though the table idea is a good one. If you know how to format it, have at it.
76:
1004:
Agreed, I admit I felt uncomfortable trying to force that part to work with the preexisting section on postpardium thyroiditis and had similar concerns.
970:
The prevalence varies significantly between studies from 1.1 to 21.1% , with estimated pooled prevalence in the general population of approximately 8%
126:
610:
Harrison's
Principles of Internal Medicine (18th edition) has a suitable table of clinical features. (I should have checked that book sooner.)
1069:
case (e.g. 15: Stagnaro-Green, 17: Pearce). Some journals have a long list of authors (e.g. 15: Stagnaro-Green, 23: Becker) while others use "
122:
270:
We can just find signs/symptoms caused by the mass effect of a thyroid goiter and add those on to the list to make it more comprehensive.
985:
I accept that the literature uses this terminology, but I don't think that we should be propagating their sloppy phrasing in
Knowledge.
1526:
107:
1206:
1073:" (e.g. 6: van den Boogaard, 7: Vissenberg). A consistent style is not required for GA status, but it is required for FA status.
175:" The preceding sentence already mentioned Hashimoto's disease. Are there other autoimmune diseases that cause hypothyroidism?
99:
69:
495:
Fixed the Reinke's edema bit, good catch on that one, I hadn't noticed it was erroneously categorized under neurological.
920:
Menorrhagia is not measured objectively. It requires a statement by the patient: "I am having unusually heavy periods".
248:" However the list only includes features due to low T3/T4. Perhaps clarify that the list only includes that group?
1262:
62:
1057:
1009:
911:
721:
634:
583:
533:
500:
452:
420:
321:
202:
161:
50:
592:
lol, it's certainly not perfect. I'll probably look to use a different source for a table of signs of symptoms.
947:
670:
1325:
1225:
1210:
1194:
1182:
1110:
1086:
1061:
1041:
1013:
998:
933:
915:
899:
850:
750:
725:
710:
691:
687:
638:
623:
605:
587:
573:
555:
537:
522:
504:
486:
456:
442:
424:
406:
366:
325:
311:
261:
232:
212:
206:
188:
165:
44:
1258:
17:
1367:
1246:
1158:
1146:
1053:
1005:
907:
871:
717:
630:
579:
542:
Re-written as a table drawn from a single authoritative source. I shall have a look at some sources.
529:
496:
448:
416:
317:
198:
157:
1333:
1170:
737:
215:: with goitre is Hashimoto's disease, without goitre is atrophic thyroiditis. However that view is
115:
1250:
962:" Also, the source describes PPT occurring during one year following pregnancy, not nine months.
797:
745:
1503:
1465:
1435:
1379:
1286:
1202:
1186:
1166:
772:
678:
1495:
1427:
1302:
1267:
1221:
1154:
1125:
863:
965:
955:
1277:
275:
415:
So, that's an error made by the person who put rapid thoughts in? If so, I'll remove it.
386:
1293:
and concentration, hearing impairment, mood instability, irritability, slow speech and
1178:
1134:
844:
92:
1520:
1431:
1108:
1084:
1039:
996:
931:
897:
741:
708:
621:
603:
578:
Sounds perfect, I'll leave it to you to rearrange that section to reflect
William's.
571:
553:
520:
484:
447:
Agreed, I'll think about how to best deal with this particular issue in the article.
440:
404:
364:
309:
259:
230:
186:
473:." I don't think that a deep voice due to Reinke's edema is a neurological feature.
1483:
1321:
1309:
1282:
1271:
1254:
1150:
1129:
1116:
Appearance: thin, brittle fingernails, dry skin, weight gain (with poor appetite),
975:
1317:
1238:
1234:
1142:
1138:
857:
840:
1453:
980:
The incidence of this syndrome has been estimated at anywhere from 1.9% to 21%.
1217:
1174:
216:
1329:
1313:
1230:
1024:". This should be standardized to a single style. Similarly with "T4" and "T
1506:
1499:
1468:
1438:
1382:
1368:"Characteristics of anemia in subclinical and overt hypothyroid patients"
1121:
1117:
1098:
1074:
1029:
986:
921:
887:
793:
698:
662:
611:
593:
561:
543:
510:
474:
430:
394:
354:
299:
249:
220:
176:
278:, discourages point-of-view pushers, and avoids inappropriate sources ("
1298:
867:
284:
Characteristics of anemia in subclinical and overt hypothyroid patients
982:" The population group isn't described—presumably it is self-evident.
1294:
1290:
1242:
1190:
1162:
1097:
I have moved the old list here in case anyone wants to refer to it.
825:
716:
should, but I am often surprised by what readers do/do not know).
736:- I hadn't noticed this page when I made some recommendations on
173:
Hypothyroidism has numerous causes such as... autoimmune disease.
280:
Hormonal causes of male sexual dysfunctions and their management
509:
As I implied above, the whole section needs to be re-written.
471:
Neurological:... deepening of the voice due to Reinke's edema
1185:
may occur due to decreased intestinal absorption of iron; a
288:
When to consider thyroid dysfunction in the neurology clinic
1366:
Erdogan M, Kosenli A, Ganidagli S, Kulaksizoglu M (2012).
211:
The general understanding is that there are two forms of
1276:
Hematological/Lymphatic: deepening of the voice due to
960:
The incidence of PPT is 5.4% in the general population.
740:. I am happy to move the advice here for completeness.
629:
extent based on
Harrison's descending frequency table.
141:
134:
103:
429:
The source itself is inappropriate for this article.
389:. Indeed the reference focuses on subclinical
1484:"The renal manifestations of thyroid disease"
385:." I was surprised to see that, so I checked
70:
8:
150:This peer review discussion has been closed.
1454:"Evaluation and management of galactorrhea"
1413:
1411:
1409:
1336:with a shallow and slow respiratory pattern
1048:I would be in favor of all of them being "T
296:The renal manifestations of thyroid disease
1126:thinning of the outer third of the eyebrow
77:
63:
32:
1261:, impaired renal function with decreased
1020:The article uses a mixture of "T3" and "T
673:in response to increased estrogen levels.
292:Evaluation and management of galactorrhea
1259:reactive (or post-prandial) hypoglycemia
1399:was invoked but never defined (see the
1352:was invoked but never defined (see the
1341:
1205:(sometimes seen with hypothyroidism in
946:" This statement could be misleading. "
35:
1189:may be caused by decreased intestinal
835:Delayed relaxation of tendon reflexes
1482:Mariani LH, Berns JS (January 2012).
759:Symptoms and signs of hypothyroidism
171:From the lead section, paragraph 2: "
7:
1394:
1347:
1452:Huang W, Molitch ME (June 2012).
24:
1207:polyglandular autoimmune syndrome
274:also helps to ensure appropriate
1432:10.1111/j.1743-6109.2012.02735.x
1395:Cite error: The named reference
1348:Cite error: The named reference
697:lol, I have clarified the text.
1324:, muscle weakness, joint pain,
813:Weight gain with poor appetite
383:Neurological:... rapid thoughts
1093:Old list of signs and symptoms
790:Poor memory and concentration
1:
1111:10:58, 25 December 2013 (UTC)
1062:07:05, 31 December 2013 (UTC)
1042:23:11, 30 December 2013 (UTC)
1014:07:05, 31 December 2013 (UTC)
999:16:10, 30 December 2013 (UTC)
942:From "Causes", paragraph 4: "
934:11:18, 25 December 2013 (UTC)
916:09:08, 25 December 2013 (UTC)
900:01:54, 24 December 2013 (UTC)
751:20:45, 23 December 2013 (UTC)
726:09:07, 25 December 2013 (UTC)
711:20:40, 23 December 2013 (UTC)
692:14:52, 23 December 2013 (UTC)
639:05:25, 23 December 2013 (UTC)
624:11:02, 22 December 2013 (UTC)
606:09:36, 21 December 2013 (UTC)
588:07:27, 21 December 2013 (UTC)
574:22:47, 20 December 2013 (UTC)
556:12:10, 20 December 2013 (UTC)
538:02:50, 20 December 2013 (UTC)
523:11:22, 19 December 2013 (UTC)
505:08:23, 19 December 2013 (UTC)
487:22:06, 18 December 2013 (UTC)
457:02:50, 20 December 2013 (UTC)
443:11:21, 19 December 2013 (UTC)
425:08:23, 19 December 2013 (UTC)
407:15:07, 18 December 2013 (UTC)
367:12:09, 20 December 2013 (UTC)
326:02:50, 20 December 2013 (UTC)
312:11:20, 19 December 2013 (UTC)
262:14:50, 18 December 2013 (UTC)
233:11:01, 19 December 2013 (UTC)
207:08:25, 19 December 2013 (UTC)
189:14:36, 18 December 2013 (UTC)
166:13:08, 18 December 2013 (UTC)
469:From "Signs and symptoms": "
381:From "Signs and symptoms": "
243:From "Signs and symptoms": "
1087:12:42, 3 January 2014 (UTC)
1543:
1263:glomerular filtration rate
1224:, decreased sweating, low
1147:elevated serum cholesterol
1527:January 2014 peer reviews
1216:Constitutional: fatigue,
862:Serous cavity effusions (
353:reflects the literature.
1143:decreased blood pressure
800:deposition in the skin)
671:thyroid binding globulin
1209:or in association with
1118:puffy face, hands, feet
1500:10.1681/ASN.2010070766
1326:carpal tunnel syndrome
1299:loss of sense of smell
1226:basal body temperature
1211:autoimmune thyroiditis
1183:iron deficiency anemia
851:Carpal tunnel syndrome
213:autoimmune thyroiditis
1330:difficulty swallowing
1301:, acute psychosis, (
1177:synthesis (decreased
738:the regular talk page
18:Knowledge:Peer review
1247:erectile dysfunction
1241:, goiter, decreased
1159:pericardial effusion
872:pericardial effusion
821:Shortness of breath
1458:Am Family Physician
1334:shortness of breath
760:
1310:depressed reflexes
1251:hyperprolactinemia
1173:) due to impaired
798:mucopolysaccharide
758:
1289:, weakness, poor
1203:pernicious anemia
1187:macrocytic anemia
1139:slowed heart rate
885:
884:
785:Cool peripheries
777:Dry, coarse skin
755:How about this:-
748:
142:Watch peer review
87:
86:
1534:
1511:
1510:
1488:J Am Soc Nephrol
1479:
1473:
1472:
1449:
1443:
1442:
1415:
1404:
1398:
1393:
1387:
1386:
1363:
1357:
1351:
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1303:myxedema madness
1268:Gastrointestinal
1222:cold intolerance
1155:pleural effusion
1107:
1103:
1083:
1079:
1038:
1034:
995:
991:
954:I am aware that
930:
926:
896:
892:
864:pleural effusion
816:Slow pulse rate
761:
757:
746:
707:
703:
684:
620:
616:
602:
598:
570:
566:
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515:
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308:
304:
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79:
72:
65:
47:
33:
1542:
1541:
1537:
1536:
1535:
1533:
1532:
1531:
1517:
1516:
1515:
1514:
1481:
1480:
1476:
1464:(11): 1073–80.
1451:
1450:
1446:
1417:
1416:
1407:
1396:
1390:
1365:
1364:
1360:
1349:
1343:
1308:Neuromuscular:
1198:
1165:(most commonly
1130:enlarged tongue
1105:
1099:
1095:
1081:
1075:
1054:TylerDurden8823
1051:
1036:
1030:
1027:
1023:
1006:TylerDurden8823
993:
987:
928:
922:
908:TylerDurden8823
894:
888:
718:TylerDurden8823
705:
699:
682:
631:TylerDurden8823
618:
612:
600:
594:
580:TylerDurden8823
568:
562:
550:
544:
530:TylerDurden8823
517:
511:
497:TylerDurden8823
481:
475:
449:TylerDurden8823
437:
431:
417:TylerDurden8823
401:
395:
361:
355:
318:TylerDurden8823
306:
300:
256:
250:
227:
221:
199:TylerDurden8823
183:
177:
158:TylerDurden8823
145:
120:
97:
91:
83:
51:Manual of Style
43:
31:
22:
21:
20:
12:
11:
5:
1540:
1538:
1530:
1529:
1519:
1518:
1513:
1512:
1474:
1444:
1405:
1388:
1358:
1340:
1339:
1338:
1337:
1306:
1280:
1278:Reinke's edema
1274:
1265:
1228:
1214:
1196:
1193:absorption or
1179:erythropoietin
1135:Cardiovascular
1132:
1094:
1091:
1090:
1089:
1065:
1064:
1049:
1045:
1044:
1025:
1021:
1017:
1016:
976:Another source
952:
951:
939:
938:
937:
936:
883:
882:
880:
876:
875:
860:
854:
853:
848:
845:oligomenorrhea
837:
836:
833:
829:
828:
822:
818:
817:
814:
810:
809:
806:
802:
801:
791:
787:
786:
783:
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769:
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28:Hypothyroidism
25:
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15:
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13:
10:
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6:
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2:
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1470:
1467:
1463:
1459:
1455:
1448:
1445:
1440:
1437:
1433:
1429:
1426:(3): 661–77.
1425:
1421:
1414:
1412:
1410:
1406:
1402:
1392:
1389:
1384:
1381:
1378:(3): 213–20.
1377:
1373:
1369:
1362:
1359:
1355:
1345:
1342:
1335:
1331:
1327:
1323:
1322:muscle cramps
1319:
1315:
1311:
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1304:
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1136:
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1123:
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1102:
1092:
1088:
1085:
1080:
1078:
1072:
1067:
1066:
1063:
1059:
1055:
1047:
1046:
1043:
1040:
1035:
1033:
1019:
1018:
1015:
1011:
1007:
1003:
1002:
1001:
1000:
997:
992:
990:
983:
981:
977:
973:
971:
967:
963:
961:
957:
956:the reference
949:
945:
941:
940:
935:
932:
927:
925:
919:
918:
917:
913:
909:
904:
903:
902:
901:
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893:
891:
881:
879:Poor hearing
878:
877:
873:
869:
865:
861:
859:
856:
855:
852:
849:
846:
842:
839:
838:
834:
832:Hoarse voice
831:
830:
827:
823:
820:
819:
815:
812:
811:
807:
805:Constipation
804:
803:
799:
795:
792:
789:
788:
784:
782:Feeling cold
781:
780:
776:
774:
771:
770:
766:
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749:
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723:
719:
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558:
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540:
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535:
531:
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524:
521:
516:
514:
508:
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494:
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492:
491:
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485:
480:
478:
472:
468:
467:
458:
454:
450:
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445:
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436:
434:
428:
427:
426:
422:
418:
414:
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412:
411:
408:
405:
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398:
392:
388:
387:the reference
384:
380:
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343:
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966:This source
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104:visual edit
1490:(Review).
1460:(Review).
1422:(Review).
1397:Mistry2009
1287:depression
1218:sleepiness
1199:deficiency
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1420:J Sex Med
1401:help page
1354:help page
1314:hypotonia
1233:: female
1231:Endocrine
1195:Vitamin B
1181:levels),
1122:hair loss
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