Knowledge (XXG)

talk:WikiProject Pharmacology - Knowledge (XXG)

Source 📝

633: 290: 272: 346: 241: 377: 210: 1031: 912:
Thanks for the feedback and help. I see that per the verifiability policy, "If available, academic and peer-reviewed publications are usually the most reliable sources on topics such as history, medicine, and science." Given the size of the study, risk of bias, and the source (JAMA), it seems solid
852:
Torgersen, Jessie; Mezochow, Alyssa K.; Newcomb, Craig W.; Carbonari, Dena M.; Hennessy, Sean; Rentsch, Christopher T.; Park, Lesley S.; Tate, Janet P.; Bräu, Norbert; Bhattacharya, Debika; Lim, Joseph K.; Mezzacappa, Catherine; Njei, Basile; Roy, Jason A.; Taddei, Tamar H.; Justice, Amy C.; Lo Re,
1108:
article. That article presents a scheme in the Synthesis section, and the aim of consulting this source is to verify that the Scheme reflects the content of this source (per WP:VERIFY). Specifically, the scheme shows conversion of theophylline into a 7-(β-chloroethyl)-analog by treatment of the
1224:-compliant). Personally, I'd delete the bibliography section, which includes some not-yet-peer-reviewed preprints. I think the question for notability is what you noted: that the molecule is only in trials, not in actual use. Given that we have the heavily populated 1125:
article. Any of the relevant quoted German text, pasted at Talk for that article, and any further comment you would wish to make, would be greatly appreciated, and would likely allow us to verify the information attributed to this source. Thank you.
129: 1275:
I've seen a lot of pharmacology navboxes (such as muscarinic receptor modulators, for an example), lots of them contain a lot of drugs that are not really known (a lot of them are redlinks), which is what I mean by "undocumented compounds"
460: 760:
15 yrs experience across various fields of medicine, including product development, patient care, and basic science. I welcome you to reach out for support with existing articles or to contribute to new topics. See you around!
913:
enough, but if reliable sources differ, that matters. I don't want to jump the gun, but I'm not convinced we need to wait. Also, the editorial IS a secondary source. LOL, you've made ~leetk (1337k) edits, Boghog.
819:
Much of the staggering mortality rates and health care costs associated with drug-induced liver injury (DILI) is clearly linked to 11 drugs not well-known for their hepatotoxic risk, per the editorial accompanying
1120:
abstract, Rücker et al first had to prepare the chemical sample they studied, hence this paper might contain a proscribed, quotable (copyable) synthetic method, and perhaps a scheme corresponding to the one at the
1202:
that I do not have the expertise to approve or decline right now. As it is within the scope of this project - is the language used appropriate for a substance that is currently used only in clinical trials?
355: 663: 425: 508: 783:
A (rather belated!) welcome over here. There don't seem to be many of us watching WikiProject Pharmacology! Regardless, let's push on. It will be great to have you working on this project too!
887: 50: 898:
describes this cohort study as an "innovative methodologic approach". We need to wait for this study to be evaluated in reliable secondary sources before citing those secondary sources.
538: 420: 437: 1064:
In furtherance of editing an article, we would ask that any individual having access to a chemistry, pharmacology, or medical library that could give access to the following article,
614: 590: 492: 197: 193: 189: 185: 181: 177: 173: 169: 704: 699: 694: 689: 684: 679: 674: 669: 578: 531: 165: 161: 157: 153: 149: 145: 141: 137: 133: 432: 201: 585: 545: 487: 466: 413: 408: 566: 456: 573: 559: 552: 479: 607: 85: 1313: 1308: 1109:
parent compound with a 1,2-dihaloethane, and then conversion of that analog, by treatment with the free base of amphetamine, to the fenethylline product (a
657: 651: 512: 1318: 474: 600: 1285:
So if anyone knew how to find lists (or something similar) with names of investigational drugs (names like "ADX-71441") that would be really great
91: 1220:
I've read the draft page. It's well-written, and reliably sourced, with the caveat that the sources are mostly minor scientific journals (but
1282:
Because so far I've been creating a lot of articles that were redlinks on the navboxes, but I'd love to add new compounds to said templates.
1242:
I accepted it through AfC after commenting out the bibliography and altering some wording here and there. One possible concern is the use of
396: 382: 297: 277: 35: 1127: 1225: 362: 31: 1038: 1024: 80: 252: 797:
Thnx much! Here if needed. I realized just today that I never joined the Medicine project, so I just did that today. Cheers!
71: 992: 735: 1279:
I was just curious if anyone knew how to find names of these compounds (like specific keywords in a search engine)
209: 124: 1180: 1159: 895: 853:
Vincent (24 June 2024). "Severe Acute Liver Injury After Hepatotoxic Medication Initiation in Real-World Data".
714: 220: 1069:
Rücker G, Neugebauer M, Neugebauer M, Heiden PG (December 1987). "Zur chemischen Stabilität des Fenetyllins" .
1008: 918: 833: 258: 1131: 988: 821: 1290: 1199: 756: 720: 894:, secondary sources (review articles) are needed to support medical claims. Furthermore the accompanying 61: 1254: 1209: 305:
on Knowledge (XXG). If you would like to participate, please visit the project page, where you can join
101: 76: 759:
to contribute here and at the Medicine project. I’m a subject matter expert in these fields with : -->
1233: 1173: 1152: 1046: 999:) had 5-10 eptkpy. Eleven of these (64%) were not included in the highest hepatotoxicity category of 802: 766: 224: 1004: 914: 829: 718: 1294: 1259: 1237: 1214: 1187: 1166: 1135: 1050: 1012: 922: 907: 806: 792: 770: 1093: 225: 1221: 891: 1286: 1086: 866: 788: 57: 1249: 1204: 1148: 1078: 952: 903: 858: 716: 632: 222: 1229: 1042: 798: 778: 762: 17: 972: 944: 444: 345: 1302: 1116:
Our presumption is that in performing the chemical stability studies reported in the
996: 948: 825: 1096: 862: 289: 271: 1122: 1105: 976: 968: 964: 960: 936: 883: 784: 302: 519: 1141: 980: 940: 899: 376: 1244: 1228:, I think there is consensus that the topic can be accepted into mainspace. -- 1104:
that they copy and paste the relevant synthetic text into a Talk entry at the
824:, which just came out. Lets get this added to the 11 to 17 relevant articles, 869: 984: 956: 932: 928: 1082: 1089: 371: 1113:
composed of theophylline and amphetamine linked by a two carbon bridge).
1000: 822:
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2820267
1030: 1110: 959:) had 10+ events per 10 000 person-years (eptkpy), while ten ( 721: 626: 340: 234: 226: 26: 1039:
Talk:Transgender hormone therapy#Requested move 15 July 2024
1029: 1025:
Talk:Transgender hormone therapy#Requested move 15 July 2024
375: 1272:
Hi, I'm not sure if this is the right place to ask this.
1041:
that may be of interest to members of this WikiProject.
109: 301:, a collaborative effort to improve the coverage of 251:does not require a rating on Knowledge (XXG)'s 38:and anything related to its purposes and tasks. 729:This page has archives. Sections older than 608: 8: 615: 601: 266: 1037:There is a requested move discussion at 315:Knowledge (XXG):WikiProject Pharmacology 844: 739:when more than 10 sections are present. 268: 7: 240: 238: 1314:NA-importance pharmacology articles 1309:Project-Class pharmacology articles 753:Howdy folks, I’ve been invited by 257:It is of interest to the following 1226:Category:Experimental cancer drugs 1056:Request for excerpt of text, from 25: 1319:WikiProject Pharmacology articles 815:Integrate definitive new findings 733:may be automatically archived by 318:Template:WikiProject Pharmacology 295:This page is within the scope of 56:New to Knowledge (XXG)? Welcome! 1268:Finding "undocumented" compounds 631: 344: 288: 270: 239: 208: 51:Click here to start a new topic. 863:10.1001/jamainternmed.2024.1836 1: 1295:22:29, 7 September 2024 (UTC) 993:sulfamethoxazole-trimethoprim 309:and see a list of open tasks. 48:Put new text under old text. 1151:. Opinions welcome. Thanks, 771:14:57, 17 January 2024 (UTC) 1198:There is a promising draft 1335: 1260:12:40, 8 August 2024 (UTC) 1238:21:40, 7 August 2024 (UTC) 1215:12:11, 7 August 2024 (UTC) 807:15:38, 3 August 2024 (UTC) 99: 18:Knowledge (XXG) talk:PHARM 1188:13:02, 28 July 2024 (UTC) 1167:22:31, 27 July 2024 (UTC) 1136:03:01, 26 July 2024 (UTC) 1051:16:08, 21 July 2024 (UTC) 1013:05:23, 29 June 2024 (UTC) 923:07:17, 26 June 2024 (UTC) 908:05:46, 26 June 2024 (UTC) 886:, which is classified as 525: 502: 447: 443: 390: 374: 283: 265: 86:Be welcoming to newcomers 352:WikiProject Pharmacology 298:WikiProject Pharmacology 36:WikiProject Pharmacology 989:amoxicillin-clavulanate 793:09:10, 7 May 2024 (UTC) 1200:Draft:Picropodophyllin 1083:10.1002/ardp.198700045 1034: 855:JAMA Internal Medicine 736:Lowercase sigmabot III 509:Requested articles (1) 380: 81:avoid personal attacks 1033: 574:Resources for editors 379: 321:pharmacology articles 202:Auto-archiving period 1118:Archiv der Pharmazie 1071:Archiv der Pharmazie 1058:Archiv der Pharmazie 391:General information 357:a WikiProject Report 366:on 17 January 2009. 1172:Actioned. Thanks. 1147:See my comment at 1035: 1023:Requested move at 658:WP:DRUGS Archive 2 652:WP:DRUGS Archive 1 539:Structure diagrams 381: 253:content assessment 92:dispute resolution 53: 1077:(12): 1272–1275. 743: 742: 660:: 8/2006 – 2/2007 654:: 6/2004 – 7/2006 625: 624: 498: 497: 370: 369: 337: 336: 333: 332: 329: 328: 233: 232: 72:Assume good faith 49: 16:(Redirected from 1326: 1257: 1252: 1212: 1207: 1194:Picropodophyllin 1185: 1178: 1164: 1157: 1149:Talk:Aclarubicin 1100: 953:prochlorperazine 874: 873: 849: 782: 738: 722: 664:WP:PHARM Archive 635: 627: 617: 610: 603: 445: 421:Reliable sources 372: 354:was featured in 348: 341: 323: 322: 319: 316: 313: 292: 285: 284: 274: 267: 244: 243: 242: 235: 227: 213: 212: 203: 112: 27: 21: 1334: 1333: 1329: 1328: 1327: 1325: 1324: 1323: 1299: 1298: 1270: 1255: 1250: 1210: 1205: 1196: 1181: 1174: 1160: 1153: 1145: 1068: 1062: 1028: 931:(86.4 eptkpy), 879: 878: 877: 851: 850: 846: 817: 776: 751: 734: 723: 717: 640: 621: 488:Editor outreach 409:Manual of Style 320: 317: 314: 311: 310: 229: 228: 223: 200: 118: 117: 116: 115: 108: 104: 97: 67: 34:for discussing 23: 22: 15: 12: 11: 5: 1332: 1330: 1322: 1321: 1316: 1311: 1301: 1300: 1269: 1266: 1265: 1264: 1263: 1262: 1195: 1192: 1191: 1190: 1144: 1139: 1102: 1101: 1061: 1054: 1027: 1021: 1020: 1019: 1018: 1017: 1016: 1015: 1005:RememberOrwell 973:clarithromycin 945:chlorpromazine 915:RememberOrwell 876: 875: 843: 842: 838: 830:RememberOrwell 816: 813: 812: 811: 810: 809: 750: 747: 745: 741: 740: 728: 725: 724: 719: 715: 713: 710: 709: 708: 707: 702: 697: 692: 687: 682: 677: 672: 667: 661: 655: 646: 645: 642: 641: 636: 630: 623: 622: 620: 619: 612: 605: 597: 594: 593: 588: 582: 581: 576: 570: 569: 563: 562: 556: 555: 549: 548: 542: 541: 535: 534: 532:Categorization 528: 527: 526:Other content 523: 522: 516: 515: 505: 504: 500: 499: 496: 495: 490: 483: 482: 477: 470: 469: 464: 452: 451: 441: 440: 435: 429: 428: 423: 417: 416: 411: 405: 404: 399: 393: 392: 388: 387: 384: 368: 367: 349: 335: 334: 331: 330: 327: 326: 324: 307:the discussion 293: 281: 280: 275: 263: 262: 256: 245: 231: 230: 221: 219: 218: 215: 214: 120: 119: 114: 113: 105: 100: 98: 96: 95: 88: 83: 74: 68: 66: 65: 54: 45: 44: 41: 40: 39: 24: 14: 13: 10: 9: 6: 4: 3: 2: 1331: 1320: 1317: 1315: 1312: 1310: 1307: 1306: 1304: 1297: 1296: 1292: 1288: 1283: 1280: 1277: 1273: 1267: 1261: 1258: 1253: 1247: 1246: 1241: 1240: 1239: 1235: 1231: 1227: 1223: 1219: 1218: 1217: 1216: 1213: 1208: 1201: 1193: 1189: 1186: 1184: 1179: 1177: 1171: 1170: 1169: 1168: 1165: 1163: 1158: 1156: 1150: 1143: 1140: 1138: 1137: 1133: 1129: 1128:98.206.30.195 1124: 1119: 1114: 1112: 1107: 1098: 1095: 1091: 1088: 1084: 1080: 1076: 1073:(in German). 1072: 1067: 1066: 1065: 1059: 1055: 1053: 1052: 1048: 1044: 1040: 1032: 1026: 1022: 1014: 1010: 1006: 1002: 998: 997:ciprofloxacin 994: 990: 986: 982: 978: 974: 970: 966: 962: 958: 954: 950: 949:metronidazole 946: 942: 938: 934: 930: 926: 925: 924: 920: 916: 911: 910: 909: 905: 901: 897: 893: 889: 885: 881: 880: 871: 868: 864: 860: 856: 848: 845: 841: 837: 835: 831: 827: 826:liver failure 823: 814: 808: 804: 800: 796: 795: 794: 790: 786: 780: 775: 774: 773: 772: 768: 764: 758: 754: 748: 746: 737: 732: 727: 726: 712: 711: 706: 703: 701: 698: 696: 693: 691: 688: 686: 683: 681: 678: 676: 673: 671: 668: 665: 662: 659: 656: 653: 650: 649: 648: 647: 644: 643: 639: 634: 629: 628: 618: 613: 611: 606: 604: 599: 598: 596: 595: 592: 589: 587: 584: 583: 580: 577: 575: 572: 571: 568: 565: 564: 561: 558: 557: 554: 551: 550: 547: 544: 543: 540: 537: 536: 533: 530: 529: 524: 521: 518: 517: 514: 510: 507: 506: 501: 494: 491: 489: 485: 484: 481: 478: 476: 472: 471: 468: 465: 462: 458: 454: 453: 450: 446: 442: 439: 436: 434: 433:Popular pages 431: 430: 427: 424: 422: 419: 418: 415: 412: 410: 407: 406: 403: 400: 398: 395: 394: 389: 386: 378: 373: 365: 364: 359: 358: 353: 350: 347: 343: 342: 339: 325: 308: 304: 300: 299: 294: 291: 287: 286: 282: 279: 276: 273: 269: 264: 260: 254: 250: 246: 237: 236: 217: 216: 211: 207: 199: 195: 191: 187: 183: 179: 175: 171: 167: 163: 159: 155: 151: 147: 143: 139: 135: 131: 128: 126: 122: 121: 111: 107: 106: 103: 93: 89: 87: 84: 82: 78: 75: 73: 70: 69: 63: 59: 58:Learn to edit 55: 52: 47: 46: 43: 42: 37: 33: 29: 28: 19: 1287:Themonkey942 1284: 1281: 1278: 1274: 1271: 1243: 1197: 1182: 1176:MidnightBlue 1175: 1161: 1155:MidnightBlue 1154: 1146: 1123:Fenethylline 1117: 1115: 1106:Fenethylline 1103: 1074: 1070: 1063: 1057: 1036: 977:ketoconazole 969:levofloxacin 965:azathioprine 961:moxifloxacin 937:lenalidomide 884:cohort study 854: 847: 839: 818: 757:WhatamIdoing 755: 752: 744: 730: 637: 586:Participants 520:Cleanup list 503:How to help 448: 401: 397:Project page 385:Pharmacology 361: 356: 351: 338: 312:Pharmacology 306: 303:Pharmacology 296: 278:Pharmacology 259:WikiProjects 249:project page 248: 205: 123: 30:This is the 1248:in places. 1142:Aclarubicin 981:fluconazole 941:thalidomide 546:Photographs 449:Departments 383:WikiProject 1303:Categories 1245:Oncotarget 1230:Tryptofish 1043:RodRabelo7 882:This is a 840:References 799:Gobucks821 779:Gobucks821 763:Gobucks821 567:Historical 457:Assessment 985:captopril 957:isoniazid 933:erlotinib 929:stavudine 896:editorial 870:2168-6106 560:Workspace 553:Templates 94:if needed 77:Be polite 32:talk page 1222:WP:MEDRS 1097:84235752 1001:LiverTox 892:WP:MEDRS 666:: 1/2007 638:Archives 475:Research 363:Signpost 125:Archives 110:WT:PHARM 102:Shortcut 62:get help 1090:3439867 939:?"or"? 927:Seven ( 890:. Per 888:primary 785:Klbrain 731:90 days 360:in the 206:90 days 1256:rabbit 1211:rabbit 1183:(Talk) 1162:(Talk) 1111:codrug 1060:(1987) 900:Boghog 828:, etc. 255:scale. 1251:Recon 1206:Recon 1094:S2CID 749:Hello 247:This 130:Index 90:Seek 1291:talk 1234:talk 1132:talk 1087:PMID 1047:talk 1009:talk 919:talk 904:talk 867:ISSN 834:talk 803:talk 789:talk 767:talk 705:2014 700:2013 695:2012 690:2011 685:2010 680:2009 675:2008 670:2007 591:talk 579:talk 493:talk 480:talk 467:talk 438:talk 426:talk 414:talk 402:talk 79:and 1079:doi 1075:320 859:doi 836:) 513:(2) 461:Log 1305:: 1293:) 1236:) 1134:) 1092:. 1085:. 1049:) 1011:) 1003:. 995:, 991:, 987:, 983:, 979:, 975:, 971:, 967:, 963:, 955:, 951:, 947:, 943:, 935:, 921:) 906:) 865:. 857:. 805:) 791:) 769:) 511:/ 486:→ 473:→ 463:) 455:→ 204:: 198:17 196:, 194:16 192:, 190:15 188:, 186:14 184:, 182:13 180:, 178:12 176:, 174:11 172:, 170:10 168:, 164:, 160:, 156:, 152:, 148:, 144:, 140:, 136:, 132:, 60:; 1289:( 1232:( 1130:( 1099:. 1081:: 1045:( 1007:( 917:( 902:( 872:. 861:: 832:( 801:( 787:( 781:: 777:@ 765:( 616:e 609:t 602:v 459:( 261:: 166:9 162:8 158:7 154:6 150:5 146:4 142:3 138:2 134:1 127:: 64:. 20:)

Index

Knowledge (XXG) talk:PHARM
talk page
WikiProject Pharmacology
Click here to start a new topic.
Learn to edit
get help
Assume good faith
Be polite
avoid personal attacks
Be welcoming to newcomers
dispute resolution
Shortcut
WT:PHARM
Archives
Index
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.