192:. She was also the co-leader of the Cancer, Immunity, and Microenvironment Program at the Hellen Diller Family Comprehensive Cancer Center and a member of the Executive Committee of the Sabre-Sandler Asthma Basic Research Center at UCSF. Her research focused on features of the microenvironment surrounding
1317:
565:
Littlepage, Laurie E.; Ewald, Andrew J.; Alexander, Caroline; Casbon, Amy-Jo; Lu, Pengfei; Kessenbrock, Kai; Provot, Sylvain; Phillips, Joanna J.; Kouros-Mehr, Hosein; Chan, Matilda; Welm, Bryan (2020-08-10).
1056:
1312:
373:
1297:
1357:
1267:
1272:
1128:
1352:
1347:
1342:
1332:
415:
1337:
1327:
385:
315:
189:
129:
1302:
227:, survived the war, with her father having fled to Italy. Her family was able to reunite at a refugee camp in Italy in 1947; they emigrated to
1307:
395:
335:
1233:
1282:
1277:
1292:
1287:
349:
and noting that, despite improvements in women's representation in the sciences since her training, sexism "has gone underground" and
405:
369:
323:
220:
42:
1322:
1158:
279:
1136:
706:
224:
303:
1242:
283:
443:
307:
1188:
Egeblad, M; Werb, Z (March 2002). "New functions for the matrix metalloproteinases in cancer progression".
267:
77:
379:
247:
72:
1080:
1262:
1257:
435:
350:
331:
197:
91:
745:
Kain, K. H. (10 August 2010). "The extracellular matrix and disease: an interview with Zena Werb".
287:
1213:
770:
1205:
1038:
989:
820:
762:
679:
633:
589:
401:
101:
223:(KZ Bergen-Belsen), a few weeks before the camp was liberated. Both of her parents, who were
1197:
1028:
1020:
979:
969:
905:
810:
802:
754:
669:
628:
623:
611:
579:
342:
152:
1243:
Fiona M. Watt, "Zena Werb", Biographical
Memoirs of the National Academy of Sciences (2021)
278:
titled "Dynamics of macrophage membrane cholesterol". After graduation she worked at the
188:(24 March 1945 – 16 June 2020) was a professor and the Vice Chair of Anatomy at the
932:
446:. The group also investigates the role of these effects on biological processes such as
1033:
1008:
984:
957:
815:
790:
463:
431:
319:
291:
208:
193:
1057:"AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship: Past Recipients"
1251:
791:"Cholesterol metabolism in the macrophage. I. The regulation of cholesterol exchange"
774:
455:
311:
1166:
612:"Zena Werb (1945–2020): Matrix Metalloproteinases, Microenvironments, and Mentoring"
482:
1217:
263:
243:
119:
974:
584:
567:
512:
459:
271:
157:
1104:
717:
411:
Lifetime
Achievement Award from Women in Cell Biology, an ASCB subgroup (2010)
327:
251:
637:
593:
1024:
451:
447:
255:
1209:
1042:
993:
806:
766:
683:
824:
462:
as a model. Her work in establishing the active role of the ECM in normal
841:
439:
201:
1165:. University of California, San Francisco. 10 April 2015. Archived from
910:
893:
235:. Though her father was previously a mathematician, he became a farmer.
1081:"Faculty Research Lecture in Basic Science 44th | UCSF Academic Senate"
758:
232:
674:
657:
466:
and in cancer progression is widely recognized as highly influential.
388:
Women in Cancer
Research Charlotte Friend Memorial Lectureship (2001)
1237:
346:
275:
228:
204:
136:
1201:
867:
539:
259:
239:
294:
from 1971 to 1973 and as a research associate from 1973 to 1975.
254:
after being told there were no accommodations for women at a
172:
1318:
Members of the United States
National Academy of Sciences
374:
Federation of
American Societies for Experimental Biology
341:
Werb wrote and gave interviews on her experiences as a
958:"Keeping Tabs on the Women: Life Scientists in Europe"
345:, describing the environment in which she trained as
1313:
Fellows of the
American Academy of Arts and Sciences
936:
421:
167:
151:
135:
125:
115:
97:
86:
65:
49:
28:
21:
391:UCSF Annual Faculty Research Lectureship (2001)
1298:University of California, San Francisco faculty
1061:American Association for Cancer Research (AACR)
1159:"Zena Werb receives UCSF 2015 Mentoring Award"
483:"About Cancer, Immunity, and Microenvironment"
430:Werb's research group studies the effects on
219:Zena Werb was born in Germany in 1945 in the
8:
356:She was a member of the Editorial Board for
351:low representation of women in top positions
330:, and in 2007 she spent a sabbatical at the
326:in 2004. She spoke of the value of academic
231:in 1948, where Werb was raised on a farm in
142:Dynamics of macrophage membrane cholesterol
1358:Members of the National Academy of Medicine
1268:Bergen-Belsen concentration camp survivors
534:
532:
416:United States National Academy of Sciences
270:in 1971, working under the supervision of
18:
1032:
983:
973:
909:
848:. University of California, San Francisco
814:
673:
627:
605:
603:
583:
546:. University of California, San Francisco
1273:Canadian people of Polish-Jewish descent
386:American Association for Cancer Research
322:in 1983. She served as president of the
60:San Francisco, California, United States
629:10.1146/annurev-cancerbio-081320-114426
516:University of California, San Francisco
487:University of California, San Francisco
474:
316:University of California, San Francisco
250:in 1966, having changed her major from
190:University of California, San Francisco
130:University of California, San Francisco
1353:21st-century Canadian women scientists
1348:20th-century Canadian women scientists
1343:21st-century American women scientists
1333:20th-century American women scientists
836:
834:
701:
699:
697:
695:
693:
1009:"The Joy of a Career in Cell Biology"
927:
925:
923:
921:
740:
738:
651:
649:
647:
396:American Academy of Arts and Sciences
336:Alexander von Humboldt Research Award
7:
795:The Journal of Experimental Medicine
789:Werb, Zena; Cohn, Zanvil A. (1971).
507:
505:
503:
438:microenvironment and its component
196:, with particular interest in the
14:
1133:American Society for Cell Biology
872:American Society for Cell Biology
714:American Society for Cell Biology
406:American Society for Cell Biology
370:FASEB Excellence in Science Award
324:American Society for Cell Biology
1338:21st-century Canadian biologists
1328:20th-century Canadian biologists
656:Watt, F. M. (22 February 2004).
221:Bergen-Belsen concentration camp
892:Hoag, Hannah (16 August 2007).
747:Disease Models & Mechanisms
616:Annual Review of Cancer Biology
280:Strangeways Research Laboratory
610:Egeblad, Mikala (2021-03-04).
1:
1303:Rockefeller University alumni
1013:Molecular Biology of the Cell
1007:Werb, Z. (15 November 2010).
956:Neugebauer, Karla M. (2006).
1308:University of Toronto alumni
975:10.1371/journal.pbio.0040097
585:10.1016/j.devcel.2020.07.012
318:in 1976, where she became a
304:visiting assistant professor
1374:
1283:German emigrants to Canada
1278:Jewish Canadian scientists
16:German-born cell biologist
1293:Canadian women biologists
1288:American women biologists
444:matrix metalloproteinases
284:Cambridge, United Kingdom
163:
108:
308:Dartmouth Medical School
215:Early life and education
1025:10.1091/mbc.E10-05-0413
662:Journal of Cell Science
568:"Zena Werb (1945–2020)"
302:Werb spent a year as a
1323:Academics from Ontario
1190:Nature Reviews. Cancer
807:10.1084/jem.134.6.1545
268:Rockefeller University
78:Rockefeller University
1163:Department of Anatomy
894:"The seven-year itch"
454:, for which they use
380:Guggenheim Fellowship
314:before moving to the
248:University of Toronto
73:University of Toronto
436:extracellular matrix
332:Max Planck Institute
200:and the role of its
198:extracellular matrix
92:extracellular matrix
1105:"E.B. Wilson Medal"
911:10.1038/nj7155-834a
353:remains a problem.
288:postdoctoral fellow
258:. She received her
933:"Zena Werb, Ph.D."
759:10.1242/dmm.006338
572:Developmental Cell
513:"Zena Werb, Ph.D."
358:Developmental Cell
238:Werb received her
1019:(22): 3764–3766.
904:(7155): 834–835.
868:"ASCB Presidents"
753:(9–10): 513–516.
675:10.1242/jcs.01031
402:E.B. Wilson Medal
364:Awards and honors
183:
182:
110:Scientific career
102:E.B. Wilson Medal
1365:
1222:
1221:
1185:
1179:
1178:
1176:
1174:
1155:
1149:
1148:
1146:
1144:
1135:. Archived from
1125:
1119:
1118:
1116:
1115:
1101:
1095:
1094:
1092:
1091:
1077:
1071:
1070:
1068:
1067:
1053:
1047:
1046:
1036:
1004:
998:
997:
987:
977:
953:
947:
946:
944:
942:
929:
916:
915:
913:
889:
883:
882:
880:
878:
864:
858:
857:
855:
853:
838:
829:
828:
818:
785:
779:
778:
742:
733:
732:
730:
728:
722:
716:. Archived from
711:
703:
688:
687:
677:
653:
642:
641:
631:
607:
598:
597:
587:
562:
556:
555:
553:
551:
536:
527:
526:
524:
522:
509:
498:
497:
495:
493:
479:
343:woman in science
179:
176:
174:
153:Doctoral advisor
147:
56:
43:KZ Bergen-Belsen
38:
36:
19:
1373:
1372:
1368:
1367:
1366:
1364:
1363:
1362:
1248:
1247:
1230:
1225:
1187:
1186:
1182:
1172:
1170:
1157:
1156:
1152:
1142:
1140:
1139:on 4 March 2016
1127:
1126:
1122:
1113:
1111:
1103:
1102:
1098:
1089:
1087:
1085:senate.ucsf.edu
1079:
1078:
1074:
1065:
1063:
1055:
1054:
1050:
1006:
1005:
1001:
955:
954:
950:
940:
938:
931:
930:
919:
891:
890:
886:
876:
874:
866:
865:
861:
851:
849:
840:
839:
832:
788:
786:
782:
744:
743:
736:
726:
724:
720:
709:
707:"ASCB Profiles"
705:
704:
691:
655:
654:
645:
609:
608:
601:
564:
563:
559:
549:
547:
538:
537:
530:
520:
518:
511:
510:
501:
491:
489:
481:
480:
476:
472:
450:maturation and
442:, particularly
428:
366:
300:
298:Academic career
217:
171:
145:
82:
61:
58:
54:
45:
40:
34:
32:
24:
17:
12:
11:
5:
1371:
1369:
1361:
1360:
1355:
1350:
1345:
1340:
1335:
1330:
1325:
1320:
1315:
1310:
1305:
1300:
1295:
1290:
1285:
1280:
1275:
1270:
1265:
1260:
1250:
1249:
1246:
1245:
1240:
1229:
1228:External links
1226:
1224:
1223:
1202:10.1038/nrc745
1180:
1169:on 5 July 2015
1150:
1120:
1096:
1072:
1048:
999:
948:
917:
884:
859:
830:
801:(6): 1545–69.
780:
734:
723:on 5 July 2015
689:
668:(6): 803–804.
643:
599:
578:(3): 299–301.
557:
528:
499:
473:
471:
468:
464:cell signaling
427:
424:
423:
422:
419:
414:Member of the
412:
409:
399:
394:Fellow of the
392:
389:
383:
377:
365:
362:
320:full professor
299:
296:
292:John T. Dingle
216:
213:
209:cell signaling
181:
180:
169:
165:
164:
161:
160:
155:
149:
148:
139:
133:
132:
127:
123:
122:
117:
113:
112:
106:
105:
99:
95:
94:
88:
87:Known for
84:
83:
81:
80:
75:
69:
67:
63:
62:
59:
57:(aged 75)
51:
47:
46:
41:
39:March 24, 1945
30:
26:
25:
22:
15:
13:
10:
9:
6:
4:
3:
2:
1370:
1359:
1356:
1354:
1351:
1349:
1346:
1344:
1341:
1339:
1336:
1334:
1331:
1329:
1326:
1324:
1321:
1319:
1316:
1314:
1311:
1309:
1306:
1304:
1301:
1299:
1296:
1294:
1291:
1289:
1286:
1284:
1281:
1279:
1276:
1274:
1271:
1269:
1266:
1264:
1261:
1259:
1256:
1255:
1253:
1244:
1241:
1239:
1235:
1232:
1231:
1227:
1219:
1215:
1211:
1207:
1203:
1199:
1196:(3): 161–74.
1195:
1191:
1184:
1181:
1168:
1164:
1160:
1154:
1151:
1138:
1134:
1130:
1129:"WICB Awards"
1124:
1121:
1110:
1106:
1100:
1097:
1086:
1082:
1076:
1073:
1062:
1058:
1052:
1049:
1044:
1040:
1035:
1030:
1026:
1022:
1018:
1014:
1010:
1003:
1000:
995:
991:
986:
981:
976:
971:
967:
963:
959:
952:
949:
937:
934:
928:
926:
924:
922:
918:
912:
907:
903:
899:
895:
888:
885:
873:
869:
863:
860:
847:
843:
837:
835:
831:
826:
822:
817:
812:
808:
804:
800:
796:
792:
787:As cited in:
784:
781:
776:
772:
768:
764:
760:
756:
752:
748:
741:
739:
735:
719:
715:
708:
702:
700:
698:
696:
694:
690:
685:
681:
676:
671:
667:
663:
659:
652:
650:
648:
644:
639:
635:
630:
625:
621:
617:
613:
606:
604:
600:
595:
591:
586:
581:
577:
573:
569:
561:
558:
545:
541:
535:
533:
529:
517:
514:
508:
506:
504:
500:
488:
484:
478:
475:
469:
467:
465:
461:
457:
456:breast cancer
453:
449:
445:
441:
437:
433:
425:
420:
417:
413:
410:
407:
403:
400:
397:
393:
390:
387:
384:
381:
378:
375:
371:
368:
367:
363:
361:
359:
354:
352:
348:
344:
339:
337:
333:
329:
325:
321:
317:
313:
312:New Hampshire
309:
305:
297:
295:
293:
289:
285:
281:
277:
273:
269:
265:
261:
257:
253:
249:
245:
241:
236:
234:
230:
226:
225:Polish-Jewish
222:
214:
212:
210:
206:
203:
199:
195:
191:
187:
178:
170:
166:
162:
159:
156:
154:
150:
143:
140:
138:
134:
131:
128:
124:
121:
118:
114:
111:
107:
103:
100:
96:
93:
90:Study of the
89:
85:
79:
76:
74:
71:
70:
68:
64:
52:
48:
44:
31:
27:
20:
1193:
1189:
1183:
1171:. Retrieved
1167:the original
1162:
1153:
1141:. Retrieved
1137:the original
1132:
1123:
1112:. Retrieved
1108:
1099:
1088:. Retrieved
1084:
1075:
1064:. Retrieved
1060:
1051:
1016:
1012:
1002:
965:
962:PLOS Biology
961:
951:
939:. Retrieved
935:
901:
897:
887:
875:. Retrieved
871:
862:
850:. Retrieved
845:
798:
794:
783:
750:
746:
725:. Retrieved
718:the original
713:
665:
661:
619:
615:
575:
571:
560:
548:. Retrieved
543:
519:. Retrieved
515:
490:. Retrieved
486:
477:
429:
357:
355:
340:
301:
264:Cell Biology
244:Biochemistry
237:
218:
185:
184:
141:
126:Institutions
120:Cell biology
109:
55:(2020-06-16)
53:16 June 2020
1263:2020 deaths
1258:1945 births
842:"Zena Werb"
658:"Zena Werb"
622:(1): 1–16.
334:through an
328:sabbaticals
272:Zanvil Cohn
158:Zanvil Cohn
1252:Categories
1114:2020-02-09
1090:2020-02-09
1066:2020-02-09
968:(4): e97.
540:"Research"
470:References
256:field site
252:geophysics
35:1945-03-24
775:116090690
638:2472-3428
594:1534-5807
452:neoplasia
448:stem cell
440:proteases
404:from the
382:(1985-6)
372:from the
246:from the
186:Zena Werb
66:Education
23:Zena Werb
1210:11990853
1043:21079003
994:16602822
846:Werb Lab
767:20699476
684:14963020
544:Werb Lab
426:Research
202:protease
1218:7990149
1034:2982121
985:1435409
825:5126640
816:2139099
434:of the
418:(2010)
408:(2007)
398:(2003)
376:(1966)
233:Ontario
205:enzymes
173:werblab
168:Website
1238:PubMed
1234:Papers
1216:
1208:
1173:4 July
1143:4 July
1041:
1031:
992:
982:
941:4 July
898:Nature
877:4 July
852:4 July
823:
813:
773:
765:
727:4 July
682:
636:
592:
550:4 July
521:4 July
492:4 July
347:sexist
276:thesis
229:Canada
146:(1971)
144:
137:Thesis
116:Fields
104:, 2007
98:Awards
1214:S2CID
771:S2CID
721:(PDF)
710:(PDF)
432:cells
290:with
286:as a
274:on a
266:from
260:Ph.D.
240:B.Sc.
194:cells
175:.ucsf
1206:PMID
1175:2015
1145:2015
1109:ASCB
1039:PMID
990:PMID
943:2015
879:2015
854:2015
821:PMID
763:PMID
729:2015
680:PMID
634:ISSN
590:ISSN
552:2015
523:2015
494:2015
460:mice
177:.edu
50:Died
29:Born
1236:on
1198:doi
1029:PMC
1021:doi
980:PMC
970:doi
906:doi
902:448
811:PMC
803:doi
799:134
755:doi
670:doi
666:117
624:doi
580:doi
458:in
310:in
306:at
282:in
262:in
242:in
207:in
1254::
1212:.
1204:.
1192:.
1161:.
1131:.
1107:.
1083:.
1059:.
1037:.
1027:.
1017:21
1015:.
1011:.
988:.
978:.
964:.
960:.
920:^
900:.
896:.
870:.
844:.
833:^
819:.
809:.
797:.
793:.
769:.
761:.
749:.
737:^
712:.
692:^
678:.
664:.
660:.
646:^
632:.
618:.
614:.
602:^
588:.
576:54
574:.
570:.
542:.
531:^
502:^
485:.
360:.
338:.
211:.
1220:.
1200::
1194:2
1177:.
1147:.
1117:.
1093:.
1069:.
1045:.
1023::
996:.
972::
966:4
945:.
914:.
908::
881:.
856:.
827:.
805::
777:.
757::
751:3
731:.
686:.
672::
640:.
626::
620:5
596:.
582::
554:.
525:.
496:.
37:)
33:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.