Knowledge (XXG)

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

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1167: 570: 560: 525: 613: 287: 575: 580: 844: 178: 197: 518: 606: 451:"Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-d-erythritol 2-phosphate to 2C-methyl-d-erythritol 2,4-cyclodiphosphate" 839: 511: 599: 1221: 1245: 799: 781: 449:
Herz S, Wungsintaweekul J, Schuhr CA, Hecht S, LĂĽttgen H, Sagner S, Fellermeier M, Eisenreich W, Zenk MH, Bacher A, Rohdich F (2000).
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The enzyme is considered a phosphorus-oxygen lyase. The
571:
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
561:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
276: 1195: 1155: 835:
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
566:
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
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4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
1051: 1015: 984: 953: 902: 822: 780: 747: 736: 716: 655: 644: 635: 196: 184: 172: 167: 147: 128: 116: 104: 92: 80: 68: 56: 51: 39: 34: 21: 581:4-hydroxy-3-methylbut-2-enyl diphosphate reductase 281: 845:Glycosylphosphatidylinositol diacylglycerol-lyase 349:have been solved for this class of enzymes, with 1215: 880: 607: 519: 8: 1222: 1208: 887: 873: 865: 744: 652: 641: 614: 600: 592: 526: 512: 504: 164: 840:Phosphatidylinositol diacylglycerol-lyase 484: 474: 323:-erythritol 2,4-cyclodiphosphate-forming) 274: 223:-erythritol 2,4-cyclodiphosphate synthase 30:-erythritol 2,4-cyclodiphosphate synthase 1162: 441: 307:2-phospho-4-(cytidine 5′-diphospho)-2- 297:-erythritol 2,4-cyclodiphosphate + CMP 18: 7: 1183: 1181: 325:. Other names in common use include 315:-erythritol CMP-lyase (cyclizing; 2- 282:{\displaystyle \rightleftharpoons } 1194:. You can help Knowledge (XXG) by 782:guanylate cyclase-coupled receptor 14: 1165: 724:Extracellular adenylate cyclase 243:YgbB N terminal protein domain 1: 249:(non-mevalonate pathway) of 245:, which participates in the 253:precursor biosynthesis. It 1267: 1246:Enzymes of known structure 1180: 455:Proc. Natl. Acad. Sci. USA 1043:Michaelis–Menten kinetics 850:FAD-AMP lyase (cyclizing) 546: 163: 935:Diffusion-limited enzyme 749:soluble guanylyl cyclase 305:of this enzyme class is 269:)erythritol 2-phosphate 257:the following reaction: 539:non-mevalonate pathway 476:10.1073/pnas.040554697 283: 1028:Eadie–Hofstee diagram 961:Allosteric regulation 284: 261:4-diphosphocytidyl-2- 1038:Lineweaver–Burk plot 556:DXP reductoisomerase 345:As of late 2007, 20 273: 241:and a member of the 233:, EC 4.6.1.12) is a 467:2000PNAS...97.2486H 997:Enzyme superfamily 930:Enzyme promiscuity 830:Cytidylate cyclase 622:Phosphorus–oxygen 341:Structural studies 279: 1203: 1202: 1153: 1152: 862: 861: 858: 857: 818: 817: 738:Guanylate cyclase 732: 731: 646:Adenylate cyclase 589: 588: 322: 314: 296: 268: 222: 212: 211: 208: 207: 111:metabolic pathway 29: 1258: 1224: 1217: 1210: 1182: 1170: 1169: 1161: 1033:Hanes–Woolf plot 976:Enzyme activator 971:Enzyme inhibitor 945:Enzyme catalysis 889: 882: 875: 866: 745: 653: 642: 616: 609: 602: 593: 528: 521: 514: 505: 499: 498: 488: 478: 446: 353:accession codes 320: 312: 294: 288: 286: 285: 280: 266: 220: 165: 27: 19: 16:Class of enzymes 1266: 1265: 1261: 1260: 1259: 1257: 1256: 1255: 1231: 1230: 1229: 1228: 1178: 1176: 1164: 1156: 1154: 1149: 1061:Oxidoreductases 1047: 1023:Enzyme kinetics 1011: 1007:List of enzymes 980: 949: 920:Catalytic triad 898: 893: 863: 854: 814: 776: 740: 728: 712: 648: 631: 620: 590: 585: 542: 532: 502: 448: 447: 443: 439: 343: 303:systematic name 271: 270: 17: 12: 11: 5: 1264: 1262: 1254: 1253: 1248: 1243: 1233: 1232: 1227: 1226: 1219: 1212: 1204: 1201: 1200: 1175: 1174: 1151: 1150: 1148: 1147: 1134: 1121: 1108: 1095: 1082: 1069: 1055: 1053: 1049: 1048: 1046: 1045: 1040: 1035: 1030: 1025: 1019: 1017: 1013: 1012: 1010: 1009: 1004: 999: 994: 988: 986: 985:Classification 982: 981: 979: 978: 973: 968: 963: 957: 955: 951: 950: 948: 947: 942: 937: 932: 927: 922: 917: 912: 906: 904: 900: 899: 894: 892: 891: 884: 877: 869: 860: 859: 856: 855: 853: 852: 847: 842: 837: 832: 826: 824: 820: 819: 816: 815: 813: 812: 806: 797: 792: 786: 784: 778: 777: 775: 774: 769: 764: 759: 753: 751: 742: 734: 733: 730: 729: 727: 726: 720: 718: 714: 713: 711: 710: 705: 700: 695: 690: 685: 680: 675: 670: 665: 659: 657: 650: 639: 633: 632: 621: 619: 618: 611: 604: 596: 587: 586: 584: 583: 578: 573: 568: 563: 558: 553: 547: 544: 543: 533: 531: 530: 523: 516: 508: 501: 500: 461:(6): 2486–90. 440: 438: 435: 342: 339: 335:MEcPP synthase 299: 298: 278: 227:MEcPP synthase 210: 209: 206: 205: 200: 194: 193: 188: 182: 181: 176: 170: 169: 161: 160: 151: 145: 144: 133: 126: 125: 120: 114: 113: 108: 102: 101: 96: 90: 89: 84: 78: 77: 72: 66: 65: 60: 54: 53: 49: 48: 43: 37: 36: 32: 31: 15: 13: 10: 9: 6: 4: 3: 2: 1263: 1252: 1249: 1247: 1244: 1242: 1239: 1238: 1236: 1225: 1220: 1218: 1213: 1211: 1206: 1205: 1199: 1197: 1193: 1190:article is a 1189: 1184: 1179: 1173: 1168: 1163: 1159: 1145: 1141: 1140: 1135: 1132: 1128: 1127: 1122: 1119: 1115: 1114: 1109: 1106: 1102: 1101: 1096: 1093: 1089: 1088: 1083: 1080: 1076: 1075: 1070: 1067: 1063: 1062: 1057: 1056: 1054: 1050: 1044: 1041: 1039: 1036: 1034: 1031: 1029: 1026: 1024: 1021: 1020: 1018: 1014: 1008: 1005: 1003: 1002:Enzyme family 1000: 998: 995: 993: 990: 989: 987: 983: 977: 974: 972: 969: 967: 966:Cooperativity 964: 962: 959: 958: 956: 952: 946: 943: 941: 938: 936: 933: 931: 928: 926: 925:Oxyanion hole 923: 921: 918: 916: 913: 911: 908: 907: 905: 901: 897: 890: 885: 883: 878: 876: 871: 870: 867: 851: 848: 846: 843: 841: 838: 836: 833: 831: 828: 827: 825: 821: 810: 807: 805: 801: 798: 796: 793: 791: 788: 787: 785: 783: 779: 773: 770: 768: 765: 763: 760: 758: 755: 754: 752: 750: 746: 743: 739: 735: 725: 722: 721: 719: 717:extracellular 715: 709: 706: 704: 701: 699: 696: 694: 691: 689: 686: 684: 681: 679: 676: 674: 671: 669: 666: 664: 661: 660: 658: 656:intracellular 654: 651: 647: 643: 640: 638: 634: 629: 625: 617: 612: 610: 605: 603: 598: 597: 594: 582: 579: 577: 574: 572: 569: 567: 564: 562: 559: 557: 554: 552: 549: 548: 545: 540: 536: 529: 524: 522: 517: 515: 510: 509: 506: 496: 492: 487: 482: 477: 472: 468: 464: 460: 456: 452: 445: 442: 436: 434: 432: 428: 424: 420: 416: 412: 408: 404: 400: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 352: 348: 340: 338: 336: 332: 328: 324: 318: 310: 304: 292: 264: 260: 259: 258: 256: 252: 248: 244: 240: 236: 232: 228: 224: 218: 204: 201: 199: 195: 192: 189: 187: 183: 180: 177: 175: 171: 166: 162: 159: 155: 152: 150: 149:Gene Ontology 146: 143: 140: 137: 134: 131: 127: 124: 121: 119: 115: 112: 109: 107: 103: 100: 97: 95: 91: 88: 87:NiceZyme view 85: 83: 79: 76: 73: 71: 67: 64: 61: 59: 55: 50: 47: 44: 42: 38: 33: 25: 20: 1196:expanding it 1185: 1177: 1139:Translocases 1136: 1123: 1110: 1097: 1084: 1074:Transferases 1071: 1058: 915:Binding site 834: 565: 551:DXP synthase 458: 454: 444: 344: 334: 330: 326: 316: 308: 306: 300: 290: 262: 230: 226: 216: 214: 213: 75:BRENDA entry 23: 1251:Lyase stubs 910:Active site 247:MEP pathway 237:-dependent 63:IntEnz view 35:Identifiers 1235:Categories 1113:Isomerases 1087:Hydrolases 954:Regulation 535:Metabolism 437:References 347:structures 311:-methyl-D- 251:isoprenoid 132:structures 99:KEGG entry 992:EC number 741:(4.6.1.2) 649:(4.6.1.1) 277:⇌ 255:catalyzes 52:Databases 1241:EC 4.6.1 1016:Kinetics 940:Cofactor 903:Activity 495:10694574 319:-methyl- 293:-methyl- 265:-methyl- 219:-Methyl- 203:proteins 191:articles 179:articles 136:RCSB PDB 46:4.6.1.12 26:-methyl- 1172:Biology 1126:Ligases 896:Enzymes 772:GUCY1B3 767:GUCY1B2 762:GUCY1A3 757:GUCY1A2 541:enzymes 463:Bibcode 158:QuickGO 123:profile 106:MetaCyc 1158:Portal 1100:Lyases 795:GUCY2D 790:GUCY2C 708:ADCY10 624:lyases 493:  483:  429:, and 239:enzyme 186:PubMed 168:Search 154:AmiGO 142:PDBsum 82:ExPASy 70:BRENDA 58:IntEnz 41:EC no. 1188:lyase 1186:This 1052:Types 823:Other 703:ADCY9 698:ADCY8 693:ADCY7 688:ADCY6 683:ADCY5 678:ADCY4 673:ADCY3 668:ADCY2 663:ADCY1 637:4.6.1 486:15955 118:PRIAM 1192:stub 1144:list 1137:EC7 1131:list 1124:EC6 1118:list 1111:EC5 1105:list 1098:EC4 1092:list 1085:EC3 1079:list 1072:EC2 1066:list 1059:EC1 809:NPR2 804:NPR1 630:4.6) 491:PMID 431:2PMP 427:2GZL 423:2AMT 419:1YQN 415:1W57 411:1W55 407:1VHA 403:1VH8 399:1U43 395:1U40 391:1U3P 387:1U3L 383:1T0A 379:1IV4 375:1IV3 371:1IV2 367:1IV1 363:1H48 359:1H47 355:1GX1 333:and 331:YgbB 327:IspF 235:zinc 231:IspF 198:NCBI 139:PDBe 94:KEGG 800:ANP 481:PMC 471:doi 351:PDB 174:PMC 130:PDB 1237:: 628:EC 537:- 489:. 479:. 469:. 459:97 457:. 453:. 433:. 425:, 421:, 417:, 413:, 409:, 405:, 401:, 397:, 393:, 389:, 385:, 381:, 377:, 373:, 369:, 365:, 361:, 357:, 337:. 329:, 289:2- 229:, 215:2- 156:/ 22:2- 1223:e 1216:t 1209:v 1198:. 1160:: 1146:) 1142:( 1133:) 1129:( 1120:) 1116:( 1107:) 1103:( 1094:) 1090:( 1081:) 1077:( 1068:) 1064:( 888:e 881:t 874:v 811:) 802:( 626:( 615:e 608:t 601:v 527:e 520:t 513:v 497:. 473:: 465:: 321:D 317:C 313:D 309:C 295:D 291:C 267:D 263:C 225:( 221:D 217:C 28:D 24:C

Index

EC no.
4.6.1.12
IntEnz
IntEnz view
BRENDA
BRENDA entry
ExPASy
NiceZyme view
KEGG
KEGG entry
MetaCyc
metabolic pathway
PRIAM
profile
PDB
RCSB PDB
PDBe
PDBsum
Gene Ontology
AmiGO
QuickGO
PMC
articles
PubMed
articles
NCBI
proteins
zinc
enzyme
YgbB N terminal protein domain

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