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3-Bromomethylphenidate

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Deutsch HM, Shi Q, Gruszecka-Kowalik E, Schweri MM (March 1996). "Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs".
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Misra M, Shi Q, Ye X, Gruszecka-Kowalik E, Bu W, Liu Z, et al. (October 2010). "Quantitative structure-activity relationship studies of threo-methylphenidate analogs".
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Pan D, Gatley SJ, Dewey SL, Chen R, Alexoff DA, Ding YS, Fowler JS (October 1994). "Binding of bromine-substituted analogs of methylphenidate to monoamine transporters".
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InChI=1S/C14H18BrNO2/c1-18-14(17)13(12-7-2-3-8-16-12)10-5-4-6-11(15)9-10/h4-6,9,12-13,16H,2-3,7-8H2,1H3/t12-,13-/m1/s1
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of a series of ring-substituted methylphenidate derivatives, and produced
61: 346: 277: 167: 158: 425: 156: 143: 110: 105: 85: 60: 35: 52:Methyl 2-(3-bromophenyl)-2-(piperidin-2-yl)acetate 74: 445: 8: 236:family, which has reportedly been sold as a 19: 491:Norepinephrine–dopamine reuptake inhibitors 240:. It showed the most potent binding to the 452: 438: 94: 27: 289: 207: 187: 49: 18: 7: 402: 400: 370:Bioorganic & Medicinal Chemistry 65: 14: 190:COC(=O)C(C1CCCCN1)C2=CC(=CC=C2)Br 404: 299:European Journal of Pharmacology 131: 122: 215:Key:JMCTXWAIACSNAZ-CHWSQXEVSA-N 128: 335:Journal of Medicinal Chemistry 134: 116: 1: 424:. You can help Knowledge by 311:10.1016/0014-2999(94)00460-9 258:3,4-Dichloromethylphenidate 248:effects in animal studies. 522: 399: 106:Chemical and physical data 506:Nervous system drug stubs 382:10.1016/j.bmc.2010.08.034 232:) is a compound from the 198: 178: 40: 26: 416:article relating to the 501:2-Piperidinyl compounds 268:4-Methylmethylphenidate 263:4-Fluoromethylphenidate 226:3-Bromomethylphenidate 21:3-Bromomethylphenidate 242:dopamine transporter 471:2-Benzylpiperidines 23: 476:Carboxylate esters 433: 432: 347:10.1021/jm950697c 273:Methylnaphthidate 223: 222: 169:Interactive image 16:Chemical compound 513: 454: 447: 440: 408: 401: 394: 393: 365: 359: 358: 329: 323: 322: 294: 171: 151: 136: 133: 130: 124: 118: 98: 78: 68: 67: 31: 24: 22: 521: 520: 516: 515: 514: 512: 511: 510: 461: 460: 459: 458: 398: 397: 376:(20): 7221–38. 367: 366: 362: 331: 330: 326: 296: 295: 291: 286: 254: 219: 216: 211: 206: 205: 194: 191: 186: 185: 174: 149: 139: 127: 121: 101: 81: 64: 56: 53: 48: 47: 17: 12: 11: 5: 519: 517: 509: 508: 503: 498: 493: 488: 483: 481:Designer drugs 478: 473: 463: 462: 457: 456: 449: 442: 434: 431: 430: 418:nervous system 409: 396: 395: 360: 324: 288: 287: 285: 282: 281: 280: 275: 270: 265: 260: 253: 250: 221: 220: 218: 217: 214: 212: 209: 201: 200: 199: 196: 195: 193: 192: 189: 181: 180: 179: 176: 175: 173: 172: 164: 162: 154: 153: 147: 141: 140: 137: 125: 119: 114: 108: 107: 103: 102: 100: 99: 91: 89: 83: 82: 80: 79: 71: 69: 58: 57: 55: 54: 51: 43: 42: 41: 38: 37: 33: 32: 15: 13: 10: 9: 6: 4: 3: 2: 518: 507: 504: 502: 499: 497: 494: 492: 489: 487: 486:Methyl esters 484: 482: 479: 477: 474: 472: 469: 468: 466: 455: 450: 448: 443: 441: 436: 435: 429: 427: 423: 419: 415: 410: 407: 403: 391: 387: 383: 379: 375: 371: 364: 361: 356: 352: 348: 344: 341:(6): 1201–9. 340: 336: 328: 325: 320: 316: 312: 308: 305:(2): 177–82. 304: 300: 293: 290: 283: 279: 276: 274: 271: 269: 266: 264: 261: 259: 256: 255: 251: 249: 247: 243: 239: 238:designer drug 235: 231: 227: 213: 208: 204: 197: 188: 184: 177: 170: 166: 165: 163: 160: 155: 148: 146: 142: 115: 113: 109: 104: 97: 93: 92: 90: 88: 84: 77: 73: 72: 70: 63: 59: 50: 46: 39: 34: 30: 25: 426:expanding it 411: 373: 369: 363: 338: 334: 327: 302: 298: 292: 229: 225: 224: 152: g·mol 36:Identifiers 496:Stimulants 465:Categories 284:References 157:3D model ( 145:Molar mass 87:ChemSpider 45:IUPAC name 246:stimulant 234:phenidate 390:20846865 252:See also 230:3-Br-MPH 96:26350024 76:52947287 355:8632426 319:7851480 150:312.207 112:Formula 62:PubChem 388:  353:  317:  278:4B-MAR 183:SMILES 420:is a 412:This 203:InChI 159:JSmol 422:stub 414:drug 386:PMID 351:PMID 315:PMID 378:doi 343:doi 307:doi 303:264 66:CID 467:: 384:. 374:18 372:. 349:. 339:39 337:. 313:. 301:. 129:Br 126:18 120:14 453:e 446:t 439:v 428:. 392:. 380:: 357:. 345:: 321:. 309:: 228:( 161:) 138:2 135:O 132:N 123:H 117:C

Index


IUPAC name
PubChem
52947287
ChemSpider
26350024
Formula
Molar mass
JSmol
Interactive image
SMILES
InChI
phenidate
designer drug
dopamine transporter
stimulant
3,4-Dichloromethylphenidate
4-Fluoromethylphenidate
4-Methylmethylphenidate
Methylnaphthidate
4B-MAR
doi
10.1016/0014-2999(94)00460-9
PMID
7851480
doi
10.1021/jm950697c
PMID
8632426
doi

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