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Bioconductor

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1353: 334:"s that are designed to demonstrate how a particular task can be accomplished with that package's software. Others provide a more thorough overview of the package or might even discuss general issues related to the package. In the future, the Bioconductor project is looking towards providing vignettes that are not specifically tied to a package, but rather are demonstrating more complex concepts. As with all aspects of the Bioconductor project, users are encouraged to participate in this effort. 198:
many Bioconductor packages have been developed to meet various data analysis needs. The use of these packages provides a basic understanding of the R programming / command language. As a result, R and Bioconductor packages, which have a strong computing background, are used by most biologists who will benefit significantly from their ability to analyze datasets. All these results provide biologists with easy access to the analysis of genomic data without requiring programming
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While computational methods continue to be developed to interpret biological data, the Bioconductor project is an open source software repository that hosts a wide range of statistical tools developed in the R programming environment. Utilizing a rich array of statistical and graphical features in R,
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Each release of Bioconductor is developed to work best with a chosen version of R. In addition to bugfixes and updates, a new release typically adds packages. The table below maps a Bioconductor release to a R version and shows the number of available Bioconductor software packages for that release.
412:(annotate package). Functions are also provided for incorporating the results of statistical analysis in HTML reports with links to annotation WWW resources. Software tools are available for assembling and processing genomic annotation data, from databases such as 329:
Each Bioconductor package contains at least one vignette, which is a document that provides a textual, task-oriented description of the package's functionality. These vignettes come in several forms. Many are simple
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The Bioconductor project aims to provide access to a wide range of powerful statistical and graphical methods for the analysis of genomic data. Analysis packages are available for: pre-processing
543:, either by contributing Bioconductor compliant packages or documentation. Additionally Bioconductor provides a mechanism for linking together different groups with 233:
microarrays. As the project has matured, the functional scope of the software packages broadened to include the analysis of all types of genomic data, such as SAGE,
1532: 359:; graph theoretical analyses; plotting genomic data. In addition, the R package system itself provides implementations for a broad range of state-of-the-art 428:
and others with the AnnotationDbi package. Data packages are distributed to provide mappings between different probe identifiers (e.g. Affy IDs, LocusLink,
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The Bioconductor project provides software for associating microarray and other genomic data in real time to biological metadata from web databases such as
1390: 186:, which corresponds to the development version of R. Most users will find the release version appropriate for their needs. In addition there are many 432:). Customized annotation libraries can also be assembled.This project also contain several functions for genomic analysis and phylogenetic (e.g. 206: 525:
by providing open and accessible tools with which to carry out that research (reproducible research is distinct from independent verification)
1542: 1527: 1260: 1231: 1207: 1358: 1547: 1537: 1395: 531: 221:, which are add-on modules for R. Initially most of the Bioconductor software packages focused on the analysis of single channel 149: 1270: 1246: 1217: 1183: 466: 238: 1289:; Leisch, Friedrich; Li, Cheng; Maechler, Martin; Rossini, Anthony J.; Sawitzki, Gunther; Smith, Colin; Smyth, Gordon; 1286: 1191: 536: 175: 38: 469:. There are many different reasons why open-source software is beneficial to the analysis of microarray data and to 1282: 1242: 1187: 462: 1491: 205:
The project was started in the Fall of 2001 and is overseen by the Bioconductor core team, based primarily at the
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The Bioconductor project has a commitment to full open source discipline, with distribution via a
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Train researchers on computational and statistical methods for the analysis of genomic data.
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To lead and encourage commercial support and development of those tools that are successful
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that allow researchers to explore and expand the methods used to analyze biological data
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packages available that are mainly, but not solely, oriented towards different types of
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each year that follow the semiannual releases of R. At any one time there is a
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Bioinformatics and Computational Biology Solutions Using R and Bioconductor
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Further scientific understanding by producing high-quality
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in the analysis of genomic data, e.g. literature data from
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on software, possibly at the level of shared development.
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Provide widespread access to a broad range of powerful
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software project for the analysis and comprehension of
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R is a programming language for statistical computing.
1273:; Carey, Vincent J.; Bates, Douglas M.; Bolstad, Ben; 119: 107: 95: 83: 63: 37: 16:Software project for the analysis of genomic data 217:Most Bioconductor components are distributed as 497:by providing appropriate tools and instruction 495:scientific computing and statistical practice 8: 483:To facilitate software improvements through 19: 1489:automated building of BioConductor packages 1391:List of open source bioinformatics software 18: 1514:CDs providing BioConductor installations. 1326: 1316: 261:methods for the analysis of genomic data. 563: 249:The broad goals of the projects are to: 1423: 325:Documentation and reproducible research 308:documentation and reproducible research 167:Bioconductor is based primarily on the 1533:Free R (programming language) software 1432:"Bioconductor – Release Announcements" 207:Fred Hutchinson Cancer Research Center 7: 1359:Free and open-source software portal 1396:List of sequence alignment software 1413:, a microarray technology platform 14: 507:To ensure that the international 473:in general. The reasons include: 339:Statistical and graphical methods 272:, annotation data from LocusLink/ 1487:distribution strives towards an 1365: 1351: 1223:R Programming for Bioinformatics 25: 1510:that have contributed bootable 357:differentially expressed genes 1: 1543:Science software for Windows 1528:Free bioinformatics software 1167: 1156: 1149: 1138: 1131: 1120: 1113: 1102: 1095: 1084: 1077: 1066: 1059: 1048: 1041: 1030: 1023: 1012: 1005: 994: 987: 976: 969: 958: 951: 940: 933: 922: 915: 904: 897: 886: 879: 868: 861: 850: 843: 832: 825: 814: 807: 796: 789: 778: 771: 760: 753: 742: 735: 724: 717: 706: 699: 688: 681: 670: 663: 652: 645: 634: 627: 616: 609: 598: 591: 580: 515:needed to carry out research 264:Facilitate the inclusion of 44:3.19 / 1 May 2024 1164: 1159: 1146: 1141: 1128: 1123: 1110: 1105: 1092: 1087: 1074: 1069: 1056: 1051: 1038: 1033: 1020: 1015: 1002: 997: 984: 979: 966: 961: 948: 943: 930: 925: 912: 907: 894: 889: 876: 871: 858: 853: 840: 835: 822: 817: 804: 799: 786: 781: 768: 763: 750: 745: 732: 727: 714: 709: 696: 691: 678: 673: 660: 655: 642: 637: 624: 619: 606: 601: 588: 583: 1564: 1548:Science software for Linux 1538:Science software for macOS 1226:. Chapman & Hall/CRC. 476:To provide full access to 1297:; Zhang, Jianhua (2004). 1252:Bioconductor Case Studies 539:are encouraged to become 426:UCSC Human Genome Project 59: 33: 24: 1498:for their distribution. 1401:R (programming language) 1318:10.1186/gb-2004-5-10-r80 480:and their implementation 418:Gene Ontology Consortium 355:array data; identifying 225:and two or more channel 1506:are projects extending 283:that enables the rapid 367:techniques, including 172:R programming language 90:R programming language 46:; 4 months ago 1483:The community of the 1479:Bioconductor Releases 1381:Computational biology 1249:; Falcon, S. (2008). 523:reproducible research 471:computational biology 1271:Gentleman, Robert C. 511:is the owner of the 509:scientific community 114:Artistic License 2.0 455:open source license 266:biological metadata 184:development version 21: 1494:2007-08-11 at the 1285:; Iacus, Stefano; 502:workbench of tools 493:To encourage good 156:data generated by 1262:978-0-387-77239-4 1233:978-1-4200-6367-7 1209:978-0-387-25146-2 1174: 1173: 400:Genome annotation 389:survival analysis 281:software platform 279:Provide a common 188:genome annotation 162:molecular biology 135: 134: 1555: 1512:Debian GNU/Linux 1485:Debian GNU/Linux 1466: 1465: 1463:Official website 1448: 1447: 1445: 1443: 1436:bioconductor.org 1428: 1375: 1370: 1369: 1361: 1356: 1355: 1354: 1340: 1330: 1320: 1295:Yang, Jean Y. H. 1287:Irizarry, Rafael 1279:Dudoit, Sandrine 1275:Dettling, Marcel 1266: 1237: 1213: 1162: 1144: 1126: 1108: 1090: 1072: 1054: 1036: 1018: 1000: 982: 964: 946: 928: 910: 892: 874: 856: 838: 820: 802: 784: 766: 748: 730: 712: 694: 676: 658: 640: 622: 604: 586: 564: 532:Open development 408:, LocusLink and 377:cluster analysis 150:open development 131: 128: 126: 65:Operating system 54: 52: 47: 29: 22: 1563: 1562: 1558: 1557: 1556: 1554: 1553: 1552: 1518: 1517: 1496:Wayback Machine 1461: 1460: 1457: 1452: 1451: 1441: 1439: 1430: 1429: 1425: 1420: 1371: 1364: 1357: 1352: 1350: 1347: 1283:Huber, Wolfgang 1269: 1263: 1240: 1234: 1216: 1210: 1182: 1179: 1160: 1142: 1124: 1106: 1088: 1070: 1052: 1034: 1016: 998: 980: 962: 944: 926: 908: 890: 872: 854: 836: 818: 800: 782: 764: 746: 728: 710: 692: 674: 656: 638: 620: 602: 584: 558: 451:SourceForge.net 320: 247: 215: 180:release version 160:experiments in 123: 55: 50: 48: 45: 17: 12: 11: 5: 1561: 1559: 1551: 1550: 1545: 1540: 1535: 1530: 1520: 1519: 1516: 1515: 1481: 1476: 1467: 1456: 1455:External links 1453: 1450: 1449: 1438:. Bioconductor 1422: 1421: 1419: 1416: 1415: 1414: 1408: 1406:DNA microarray 1403: 1398: 1393: 1388: 1386:Bioinformatics 1383: 1377: 1376: 1373:Biology portal 1362: 1346: 1343: 1342: 1341: 1304:Genome Biology 1267: 1261: 1238: 1232: 1214: 1208: 1178: 1175: 1172: 1171: 1166: 1163: 1158: 1154: 1153: 1148: 1145: 1140: 1136: 1135: 1130: 1127: 1122: 1118: 1117: 1112: 1109: 1104: 1100: 1099: 1094: 1091: 1086: 1082: 1081: 1076: 1073: 1068: 1064: 1063: 1058: 1055: 1050: 1046: 1045: 1040: 1037: 1032: 1028: 1027: 1022: 1019: 1014: 1010: 1009: 1004: 1001: 996: 992: 991: 986: 983: 978: 974: 973: 968: 965: 960: 956: 955: 950: 947: 942: 938: 937: 932: 929: 924: 920: 919: 914: 911: 906: 902: 901: 896: 893: 888: 884: 883: 878: 875: 870: 866: 865: 860: 857: 852: 848: 847: 842: 839: 834: 830: 829: 824: 821: 816: 812: 811: 806: 803: 798: 794: 793: 788: 785: 780: 776: 775: 770: 767: 762: 758: 757: 752: 749: 744: 740: 739: 734: 731: 726: 722: 721: 716: 713: 708: 704: 703: 698: 695: 690: 686: 685: 680: 677: 672: 668: 667: 662: 659: 654: 650: 649: 644: 641: 636: 632: 631: 626: 623: 618: 614: 613: 608: 605: 600: 596: 595: 590: 587: 582: 578: 577: 574: 573:Package count 571: 568: 557: 554: 553: 552: 528: 527: 526: 519: 516: 513:software tools 505: 498: 491: 481: 441: 396: 335: 319: 316: 315: 314: 311: 304: 277: 262: 246: 243: 214: 211: 133: 132: 121: 117: 116: 111: 105: 104: 102:Bioinformatics 99: 93: 92: 87: 81: 80: 67: 61: 60: 57: 56: 43: 41: 39:Stable release 35: 34: 31: 30: 15: 13: 10: 9: 6: 4: 3: 2: 1560: 1549: 1546: 1544: 1541: 1539: 1536: 1534: 1531: 1529: 1526: 1525: 1523: 1513: 1509: 1505: 1501: 1497: 1493: 1490: 1486: 1482: 1480: 1477: 1474: 1471: 1470:The R Project 1468: 1464: 1459: 1458: 1454: 1437: 1433: 1427: 1424: 1417: 1412: 1409: 1407: 1404: 1402: 1399: 1397: 1394: 1392: 1389: 1387: 1384: 1382: 1379: 1378: 1374: 1368: 1363: 1360: 1349: 1344: 1338: 1334: 1329: 1324: 1319: 1314: 1310: 1306: 1305: 1300: 1296: 1292: 1291:Tierney, Luke 1288: 1284: 1280: 1276: 1272: 1268: 1264: 1258: 1254: 1253: 1248: 1247:Gentleman, R. 1244: 1239: 1235: 1229: 1225: 1224: 1219: 1218:Gentleman, R. 1215: 1211: 1205: 1201: 1197: 1193: 1189: 1186:; Carey, V.; 1185: 1184:Gentleman, R. 1181: 1180: 1176: 1170: 1155: 1152: 1137: 1134: 1119: 1116: 1101: 1098: 1083: 1080: 1065: 1062: 1047: 1044: 1029: 1026: 1011: 1008: 993: 990: 975: 972: 957: 954: 939: 936: 921: 918: 903: 900: 885: 882: 867: 864: 849: 846: 831: 828: 813: 810: 795: 792: 777: 774: 759: 756: 741: 738: 723: 720: 705: 702: 687: 684: 669: 666: 651: 648: 633: 630: 615: 612: 597: 594: 579: 576:R dependency 575: 572: 570:Release date 569: 566: 565: 562: 555: 550: 549:collaboration 546: 542: 538: 535: 533: 529: 524: 520: 517: 514: 510: 506: 503: 500:To provide a 499: 496: 492: 490: 486: 482: 479: 475: 474: 472: 468: 464: 460: 456: 452: 448: 446: 442: 440:packages ..). 439: 435: 431: 427: 423: 420:, LocusLink, 419: 415: 411: 407: 403: 401: 397: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 354: 350: 346: 342: 340: 336: 333: 328: 326: 322: 321: 318:Main features 317: 312: 309: 305: 302: 301:interoperable 298: 294: 290: 286: 282: 278: 275: 271: 267: 263: 260: 256: 252: 251: 250: 244: 242: 240: 236: 232: 228: 224: 220: 212: 210: 208: 203: 201: 195: 193: 189: 185: 181: 177: 173: 170: 165: 163: 159: 155: 151: 147: 143: 139: 130: 127:.bioconductor 122: 118: 115: 112: 110: 106: 103: 100: 98: 94: 91: 88: 86: 82: 79: 75: 71: 68: 66: 62: 58: 42: 40: 36: 32: 28: 23: 1440:. 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Index


Stable release
Operating system
Linux
macOS
Windows
Platform
R programming language
Type
Bioinformatics
License
Artistic License 2.0
www.bioconductor.org
free
open source
open development
genomic
wet lab
molecular biology
statistical
R programming language
releases
release version
development version
genome annotation
microarrays
expertise
Fred Hutchinson Cancer Research Center
R packages
Affymetrix

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