2012:
580:
Holmes RS, Wright MW, Laulederkind SJ, Cox LA, Hosokawa M, Imai T, Ishibashi S, Lehner R, Miyazaki M, Perkins EJ, Potter PM, Redinbo MR, Robert J, Satoh T, Yamashita T, Yan B, Yokoi T, Zechner R, Maltais LJ (2010).
261:
813:
Mentlein R, Schumann M, Heymann E (1984). "Comparative chemical and immunological characterization of five lipolytic enzymes (carboxylesterases) from rat liver microsomes".
520:
Aranda, Juan; Cerqueira, N. M. F. S. A.; Fernandes, P.A.; Roca, M.; Tuñon, I.; Ramos, M. J. (2014). "The
Catalytic Mechanism of Carboxylesterases. A Computational Study".
179:
198:
1086:
1333:
1247:
771:
Horgan DJ, Stoops JK, Webb EC, Zerner B (1969). "Carboxylesterases (EC 3.1.1). A large-scale purification of pig liver carboxylesterase".
842:
Runnegar MT, Scott K, Webb EC, Zerner B (1969). "Carboxylesterases (EC 3.1.1). Purification and titration of ox liver carboxylesterase".
1348:
1342:
1143:
893:
1191:
1731:
1302:
1091:
191:
1409:
1297:
635:
Augusteyn RC, de Jersey J, Webb EC, Zerner B (1969). "On the homology of the active-site peptides of liver carboxylesterases".
1218:
1128:
1081:
118:
1887:
142:
1640:
1581:
1685:
1252:
1242:
1645:
1537:
1162:
583:"Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins"
2002:
1231:
1227:
1223:
1139:
972:
312:
1872:
1988:
1975:
1962:
1949:
1936:
1923:
1910:
1493:
1439:
1399:
1358:
1262:
1101:
1069:
955:
919:
1882:
1836:
1779:
1147:
996:
910:
136:
29:
279:
1784:
1016:
886:
366:
123:
299:
Carboxylesterases are widely distributed in nature, and are common in mammalian liver. Many participate in
1572:
1211:
315:
by other enzymes to increase solubility and eventually excreted. The essential polyunsaturated fatty acid
246:
1805:
1724:
1507:
1404:
1196:
1157:
1021:
943:
203:
1877:
111:
1690:
1525:
1520:
1453:
1113:
938:
503:
An approved nomenclature has been established for the five mammalian carboxylesterase gene families.
387:
374:
46:
1841:
1545:
1515:
1319:
1314:
1238:
1174:
960:
264:
41:
139:
1774:
1678:
1530:
1011:
1001:
879:
492:
487:
482:
477:
472:
414:
409:
404:
343:
63:
2032:
1479:
1424:
1392:
1267:
986:
859:
830:
788:
759:
716:
681:
652:
612:
537:
370:
288:
130:
373:
to each other) includes a number of proteins with different substrate specificities, such as
1820:
1815:
1789:
1717:
1555:
1135:
1040:
1035:
991:
851:
822:
780:
749:
741:
706:
673:
644:
602:
594:
529:
449:
316:
275:
1867:
1851:
1764:
1657:
1471:
1387:
1382:
1377:
1290:
1285:
1045:
923:
300:
99:
75:
2016:
1905:
1846:
1630:
1625:
1620:
1006:
981:
977:
950:
933:
754:
729:
711:
695:"Hydrolysis of vitamin A acetate by unspecific carboxylesterases from liver and kidney"
694:
607:
582:
283:
174:
34:
154:
2026:
1810:
1769:
1371:
1280:
1030:
826:
648:
347:
149:
1759:
1498:
1429:
1152:
1073:
556:
1983:
1918:
1754:
1673:
1444:
1338:
1201:
1167:
1105:
871:
339:
308:
304:
268:
158:
2011:
1650:
598:
1957:
1931:
1563:
1362:
1275:
902:
228:
763:
616:
541:
863:
834:
792:
720:
685:
656:
1608:
1603:
1598:
1419:
1054:
906:
800:
Malhotra OP, Philip G (1966). "Specificity of goat intestinal esterase".
457:
326:
855:
784:
677:
664:
Barker DL, Jencks WP (1969). "Pig liver esterase. Physical properties".
1615:
1593:
1588:
1206:
106:
87:
745:
533:
292:
1970:
1740:
1635:
1568:
1461:
1059:
967:
332:
320:
186:
82:
70:
58:
1944:
1577:
1328:
1324:
236:
1309:
1186:
1179:
1123:
1118:
497:
94:
1713:
875:
362:
18:2, n-6), has a role as a human carboxylesterase inhibitor.
468:
Humans genes that encode carboxylesterase enzymes include:
1709:
730:"The purification and properties of horse liver esterase"
250:
2000:
369:
of evolutionarily related proteins (those with clear
249:
1896:
1860:
1829:
1798:
1747:
1666:
1554:
1506:
1492:
1470:
1452:
1438:
1418:
1357:
1261:
1100:
1068:
918:
197:
185:
173:
168:
148:
129:
117:
105:
93:
81:
69:
57:
52:
40:
28:
23:
18:
255:
1197:Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase
278:belonging to the superfamily of proteins with
1725:
887:
8:
282:. Some exceptions include an esterase with
1732:
1718:
1710:
1503:
1449:
1435:
894:
880:
872:
165:
753:
710:
606:
248:
346:), formed by the synthesis from dietary
2007:
1087:Ubiquitin carboxy-terminal hydrolase L1
512:
307:such as toxins or drugs; the resulting
15:
1667:either deoxy- or ribo-
456:The last enzyme also participates in
7:
1248:Protein serine/threonine phosphatase
1349:Cyclic nucleotide phosphodiesterase
1343:Clostridium perfringens alpha toxin
1144:Tartrate-resistant acid phosphatase
256:{\displaystyle \rightleftharpoons }
1192:Pyruvate dehydrogenase phosphatase
712:10.1111/j.1432-1033.1969.tb00748.x
14:
1092:4-hydroxybenzoyl-CoA thioesterase
274:Most enzymes from this group are
231:reactions of the following form:
2010:
1410:N-acetylglucosamine-6-sulfatase
1298:Sphingomyelin phosphodiesterase
1219:Inositol-phosphate phosphatase
1082:Palmitoyl protein thioesterase
223:, EC 3.1.1.1; systematic name
1:
1582:RNA-induced silencing complex
1686:Serratia marcescens nuclease
1253:Dual-specificity phosphatase
1243:Protein tyrosine phosphatase
827:10.1016/0003-9861(84)90311-4
693:Bertram J, Krisch K (1969).
649:10.1016/0005-2744(69)90112-0
1163:Fructose 1,6-bisphosphatase
2049:
225:carboxylic-ester hydrolase
221:carboxylic-ester hydrolase
1888:Michaelis–Menten kinetics
1400:Galactosamine-6 sulfatase
956:6-phosphogluconolactonase
599:10.1007/s00335-010-9284-4
164:
1780:Diffusion-limited enzyme
1148:Purple acid phosphatases
561:pubchem.ncbi.nlm.nih.gov
431:methylbutyrate esterase,
446:vitamin A esterase, and
367:carboxylesterase family
1573:Microprocessor complex
1212:Beta-propeller phytase
815:Arch. Biochem. Biophys
637:Biochim. Biophys. Acta
257:
1873:Eadie–Hofstee diagram
1806:Allosteric regulation
1508:Endodeoxyribonuclease
1405:Iduronate-2-sulfatase
1158:Glucose 6-phosphatase
944:Butyrylcholinesterase
375:acetylcholinesterases
258:
1883:Lineweaver–Burk plot
1691:Micrococcal nuclease
1526:Deoxyribonuclease IV
1521:Deoxyribonuclease II
1454:Exodeoxyribonuclease
1114:Alkaline phosphatase
939:Acetylcholinesterase
388:acetylcholinesterase
247:
1546:UvrABC endonuclease
1516:Deoxyribonuclease I
1239:Protein phosphatase
1175:Protein phosphatase
973:Bile salt-dependent
961:PAF acetylhydrolase
856:10.1021/bi00833a035
785:10.1021/bi00833a033
678:10.1021/bi00838a001
443:triacetin esterase,
440:propionyl esterase,
1842:Enzyme superfamily
1775:Enzyme promiscuity
1679:Mung bean nuclease
1538:Restriction enzyme
1531:Restriction enzyme
557:"Arachidonic acid"
437:procaine esterase,
415:carboxylesterase 3
410:carboxylesterase 2
405:carboxylesterase 1
398:butyrate esterase,
301:phase I metabolism
280:α/β hydrolase fold
253:
1998:
1997:
1707:
1706:
1703:
1702:
1699:
1698:
1488:
1487:
1480:Oligonucleotidase
1425:deoxyribonuclease
1393:Steroid sulfatase
1268:Phosphodiesterase
997:Hormone-sensitive
746:10.1042/bj0580415
534:10.1021/bi500934j
528:(36): 5820–5829.
401:butyryl esterase,
371:sequence homology
286:-like structure (
276:serine hydrolases
213:
212:
209:
208:
112:metabolic pathway
2040:
2015:
2014:
2006:
1878:Hanes–Woolf plot
1821:Enzyme activator
1816:Enzyme inhibitor
1790:Enzyme catalysis
1734:
1727:
1720:
1711:
1556:Endoribonuclease
1542:
1536:
1504:
1450:
1436:
1136:Acid phosphatase
1017:Monoacylglycerol
927:ester hydrolases
896:
889:
882:
873:
867:
838:
809:
796:
767:
757:
728:BURCH J (1954).
724:
714:
689:
660:
621:
620:
610:
593:(9–10): 427–41.
577:
571:
570:
568:
567:
552:
546:
545:
517:
450:cocaine esterase
317:arachidonic acid
295:
262:
260:
259:
254:
237:carboxylic ester
217:carboxylesterase
166:
19:carboxylesterase
16:
2048:
2047:
2043:
2042:
2041:
2039:
2038:
2037:
2023:
2022:
2021:
2009:
2001:
1999:
1994:
1906:Oxidoreductases
1892:
1868:Enzyme kinetics
1856:
1852:List of enzymes
1825:
1794:
1765:Catalytic triad
1743:
1738:
1708:
1695:
1662:
1550:
1540:
1534:
1497:
1484:
1472:Exoribonuclease
1466:
1443:
1427:
1423:
1414:
1388:Arylsulfatase L
1383:Arylsulfatase B
1378:Arylsulfatase A
1353:
1266:
1257:
1096:
1064:
926:
914:
900:
870:
841:
812:
799:
770:
727:
699:Eur. J. Biochem
692:
672:(10): 3879–89.
663:
634:
630:
628:Further reading
625:
624:
579:
578:
574:
565:
563:
554:
553:
549:
519:
518:
514:
509:
466:
454:
428:methylbutyrase,
383:
361:
357:
353:
337:
331:
325:
287:
245:
244:
242:
12:
11:
5:
2046:
2044:
2036:
2035:
2025:
2024:
2020:
2019:
1996:
1995:
1993:
1992:
1979:
1966:
1953:
1940:
1927:
1914:
1900:
1898:
1894:
1893:
1891:
1890:
1885:
1880:
1875:
1870:
1864:
1862:
1858:
1857:
1855:
1854:
1849:
1844:
1839:
1833:
1831:
1830:Classification
1827:
1826:
1824:
1823:
1818:
1813:
1808:
1802:
1800:
1796:
1795:
1793:
1792:
1787:
1782:
1777:
1772:
1767:
1762:
1757:
1751:
1749:
1745:
1744:
1739:
1737:
1736:
1729:
1722:
1714:
1705:
1704:
1701:
1700:
1697:
1696:
1694:
1693:
1688:
1683:
1682:
1681:
1670:
1668:
1664:
1663:
1661:
1660:
1655:
1654:
1653:
1648:
1643:
1638:
1628:
1623:
1618:
1613:
1612:
1611:
1606:
1601:
1596:
1586:
1585:
1584:
1575:
1560:
1558:
1552:
1551:
1549:
1548:
1543:
1528:
1523:
1518:
1512:
1510:
1501:
1490:
1489:
1486:
1485:
1483:
1482:
1476:
1474:
1468:
1467:
1465:
1464:
1458:
1456:
1447:
1433:
1416:
1415:
1413:
1412:
1407:
1402:
1397:
1396:
1395:
1390:
1385:
1380:
1367:
1365:
1355:
1354:
1352:
1351:
1346:
1336:
1331:
1322:
1317:
1312:
1307:
1306:
1305:
1295:
1294:
1293:
1288:
1278:
1272:
1270:
1259:
1258:
1256:
1255:
1250:
1245:
1236:
1235:
1234:
1216:
1215:
1214:
1204:
1199:
1194:
1189:
1184:
1183:
1182:
1172:
1171:
1170:
1160:
1155:
1150:
1133:
1132:
1131:
1126:
1121:
1110:
1108:
1098:
1097:
1095:
1094:
1089:
1084:
1078:
1076:
1066:
1065:
1063:
1062:
1057:
1051:
1050:
1049:
1048:
1043:
1038:
1027:
1026:
1025:
1024:
1022:Diacylglycerol
1019:
1014:
1009:
1004:
999:
994:
989:
984:
975:
964:
963:
958:
953:
951:Pectinesterase
948:
947:
946:
941:
934:Cholinesterase
930:
928:
916:
915:
901:
899:
898:
891:
884:
876:
869:
868:
839:
810:
797:
768:
725:
690:
661:
631:
629:
626:
623:
622:
572:
547:
511:
510:
508:
505:
501:
500:
495:
490:
485:
480:
475:
465:
462:
460:biosynthesis.
453:
452:
447:
444:
441:
438:
435:
432:
429:
426:
423:
420:
417:
412:
407:
402:
399:
396:
393:
390:
384:
382:
379:
359:
355:
351:
335:
329:
323:
272:
271:
252:
240:
211:
210:
207:
206:
201:
195:
194:
189:
183:
182:
177:
171:
170:
162:
161:
152:
146:
145:
134:
127:
126:
121:
115:
114:
109:
103:
102:
97:
91:
90:
85:
79:
78:
73:
67:
66:
61:
55:
54:
50:
49:
44:
38:
37:
32:
26:
25:
21:
20:
13:
10:
9:
6:
4:
3:
2:
2045:
2034:
2031:
2030:
2028:
2018:
2013:
2008:
2004:
1990:
1986:
1985:
1980:
1977:
1973:
1972:
1967:
1964:
1960:
1959:
1954:
1951:
1947:
1946:
1941:
1938:
1934:
1933:
1928:
1925:
1921:
1920:
1915:
1912:
1908:
1907:
1902:
1901:
1899:
1895:
1889:
1886:
1884:
1881:
1879:
1876:
1874:
1871:
1869:
1866:
1865:
1863:
1859:
1853:
1850:
1848:
1847:Enzyme family
1845:
1843:
1840:
1838:
1835:
1834:
1832:
1828:
1822:
1819:
1817:
1814:
1812:
1811:Cooperativity
1809:
1807:
1804:
1803:
1801:
1797:
1791:
1788:
1786:
1783:
1781:
1778:
1776:
1773:
1771:
1770:Oxyanion hole
1768:
1766:
1763:
1761:
1758:
1756:
1753:
1752:
1750:
1746:
1742:
1735:
1730:
1728:
1723:
1721:
1716:
1715:
1712:
1692:
1689:
1687:
1684:
1680:
1677:
1676:
1675:
1672:
1671:
1669:
1665:
1659:
1656:
1652:
1649:
1647:
1644:
1642:
1639:
1637:
1634:
1633:
1632:
1629:
1627:
1624:
1622:
1619:
1617:
1614:
1610:
1607:
1605:
1602:
1600:
1597:
1595:
1592:
1591:
1590:
1587:
1583:
1579:
1576:
1574:
1570:
1567:
1566:
1565:
1562:
1561:
1559:
1557:
1553:
1547:
1544:
1539:
1532:
1529:
1527:
1524:
1522:
1519:
1517:
1514:
1513:
1511:
1509:
1505:
1502:
1500:
1495:
1491:
1481:
1478:
1477:
1475:
1473:
1469:
1463:
1460:
1459:
1457:
1455:
1451:
1448:
1446:
1441:
1437:
1434:
1431:
1426:
1421:
1417:
1411:
1408:
1406:
1403:
1401:
1398:
1394:
1391:
1389:
1386:
1384:
1381:
1379:
1376:
1375:
1374:
1373:
1372:arylsulfatase
1369:
1368:
1366:
1364:
1360:
1356:
1350:
1347:
1344:
1340:
1337:
1335:
1332:
1330:
1326:
1323:
1321:
1318:
1316:
1313:
1311:
1308:
1304:
1301:
1300:
1299:
1296:
1292:
1289:
1287:
1284:
1283:
1282:
1281:Phospholipase
1279:
1277:
1274:
1273:
1271:
1269:
1264:
1260:
1254:
1251:
1249:
1246:
1244:
1240:
1237:
1233:
1229:
1225:
1222:
1221:
1220:
1217:
1213:
1210:
1209:
1208:
1205:
1203:
1200:
1198:
1195:
1193:
1190:
1188:
1185:
1181:
1178:
1177:
1176:
1173:
1169:
1166:
1165:
1164:
1161:
1159:
1156:
1154:
1151:
1149:
1145:
1141:
1137:
1134:
1130:
1127:
1125:
1122:
1120:
1117:
1116:
1115:
1112:
1111:
1109:
1107:
1103:
1099:
1093:
1090:
1088:
1085:
1083:
1080:
1079:
1077:
1075:
1071:
1067:
1061:
1058:
1056:
1053:
1052:
1047:
1044:
1042:
1039:
1037:
1034:
1033:
1032:
1031:Phospholipase
1029:
1028:
1023:
1020:
1018:
1015:
1013:
1010:
1008:
1005:
1003:
1000:
998:
995:
993:
990:
988:
985:
983:
979:
976:
974:
971:
970:
969:
966:
965:
962:
959:
957:
954:
952:
949:
945:
942:
940:
937:
936:
935:
932:
931:
929:
925:
921:
917:
912:
908:
904:
897:
892:
890:
885:
883:
878:
877:
874:
865:
861:
857:
853:
850:(5): 2013–8.
849:
845:
840:
836:
832:
828:
824:
821:(2): 612–21.
820:
816:
811:
807:
803:
798:
794:
790:
786:
782:
779:(5): 2000–6.
778:
774:
769:
765:
761:
756:
751:
747:
743:
740:(3): 415–26.
739:
735:
731:
726:
722:
718:
713:
708:
704:
700:
696:
691:
687:
683:
679:
675:
671:
667:
662:
658:
654:
650:
646:
643:(1): 128–37.
642:
638:
633:
632:
627:
618:
614:
609:
604:
600:
596:
592:
588:
584:
576:
573:
562:
558:
551:
548:
543:
539:
535:
531:
527:
523:
516:
513:
506:
504:
499:
496:
494:
491:
489:
486:
484:
481:
479:
476:
474:
471:
470:
469:
463:
461:
459:
451:
448:
445:
442:
439:
436:
434:monobutyrase,
433:
430:
427:
424:
421:
418:
416:
413:
411:
408:
406:
403:
400:
397:
394:
392:ali-esterase,
391:
389:
386:
385:
380:
378:
376:
372:
368:
363:
349:
348:linoleic acid
345:
341:
334:
328:
322:
318:
314:
310:
306:
302:
297:
294:
290:
285:
281:
277:
270:
266:
238:
234:
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226:
222:
218:
205:
202:
200:
196:
193:
190:
188:
184:
181:
178:
176:
172:
167:
163:
160:
156:
153:
151:
150:Gene Ontology
147:
144:
141:
138:
135:
132:
128:
125:
122:
120:
116:
113:
110:
108:
104:
101:
98:
96:
92:
89:
88:NiceZyme view
86:
84:
80:
77:
74:
72:
68:
65:
62:
60:
56:
51:
48:
45:
43:
39:
36:
33:
31:
27:
22:
17:
1984:Translocases
1981:
1968:
1955:
1942:
1929:
1919:Transferases
1916:
1903:
1760:Binding site
1541:}}
1535:{{
1499:Endonuclease
1430:ribonuclease
1370:
1153:Nucleotidase
1074:Thioesterase
847:
844:Biochemistry
843:
818:
814:
805:
801:
776:
773:Biochemistry
772:
737:
733:
705:(1): 122–6.
702:
698:
669:
666:Biochemistry
665:
640:
636:
590:
587:Mamm. Genome
586:
575:
564:. Retrieved
560:
550:
525:
522:Biochemistry
521:
515:
502:
467:
455:
364:
309:carboxylates
298:
273:
224:
220:
216:
214:
76:BRENDA entry
1755:Active site
1674:Nuclease S1
1445:Exonuclease
1339:Lecithinase
1168:Calcineurin
1106:Phosphatase
1012:Lipoprotein
1002:Endothelial
425:esterase D,
422:esterase B,
419:esterase A,
395:B-esterase,
305:xenobiotics
284:β-lactamase
269:carboxylate
215:The enzyme
64:IntEnz view
24:Identifiers
1958:Isomerases
1932:Hydrolases
1799:Regulation
987:Pancreatic
924:Carboxylic
808:: 386–402.
802:Biochem. Z
734:Biochem. J
566:2022-11-24
507:References
313:conjugated
296:).
133:structures
100:KEGG entry
47:9016-18-6
1837:EC number
1564:RNase III
1422:(includes
1363:Sulfatase
1276:Autotaxin
1140:Prostatic
992:Lysosomal
907:esterases
903:Hydrolase
555:PubChem.
311:are then
251:⇌
229:catalyzes
53:Databases
2033:EC 3.1.1
2027:Category
1861:Kinetics
1785:Cofactor
1748:Activity
1658:RNase T1
1420:Nuclease
1055:Cutinase
764:13208632
617:20931200
542:25101647
458:alkaloid
381:Examples
204:proteins
192:articles
180:articles
137:RCSB PDB
2017:Biology
1971:Ligases
1741:Enzymes
1631:RNase E
1626:RNase Z
1621:RNase A
1616:RNase P
1589:RNase H
1207:Phytase
1007:Hepatic
982:Lingual
978:Gastric
864:5785222
835:6208846
793:5785220
755:1269916
721:5353595
686:4981346
657:4884138
608:3127206
265:alcohol
159:QuickGO
124:profile
107:MetaCyc
42:CAS no.
35:3.1.1.1
2003:Portal
1945:Lyases
1569:Drosha
1494:3.1.21
1462:RecBCD
1440:3.1.11
1060:PETase
968:Lipase
862:
833:
791:
762:
752:
719:
684:
655:
615:
605:
540:
350:(LA: C
187:PubMed
169:Search
155:AmiGO
143:PDBsum
83:ExPASy
71:BRENDA
59:IntEnz
30:EC no.
1897:Types
1578:Dicer
1533:;see
1359:3.1.6
1329:PDE4B
1325:PDE4A
1263:3.1.4
1232:IMPA3
1228:IMPA2
1224:IMPA1
1102:3.1.3
1070:3.1.2
920:3.1.1
464:Genes
338:; 20:
119:PRIAM
1989:list
1982:EC7
1976:list
1969:EC6
1963:list
1956:EC5
1950:list
1943:EC4
1937:list
1930:EC3
1924:list
1917:EC2
1911:list
1904:EC1
1496:-31:
1442:-16:
1428:and
1334:PDE5
1320:PDE3
1315:PDE2
1310:PDE1
1202:PTEN
1187:OCRL
1180:PP2A
1129:ALPP
1124:ALPL
1119:ALPI
913:3.1)
860:PMID
831:PMID
789:PMID
760:PMID
717:PMID
682:PMID
653:PMID
613:PMID
538:PMID
498:CES8
493:CES7
488:CES4
483:CES3
478:CES2
473:CES1
365:The
319:(AA
293:1ci8
267:+ a
219:(or
199:NCBI
140:PDBe
95:KEGG
1651:4/5
852:doi
823:doi
819:234
806:346
781:doi
750:PMC
742:doi
707:doi
674:doi
645:doi
641:171
603:PMC
595:doi
530:doi
344:n-6
303:of
289:PDB
263:an
239:+ H
175:PMC
131:PDB
2029::
1609:2C
1604:2B
1599:2A
1580::
1571::
1361::
1241::
1230:,
1226:,
1142:)/
1104::
1072::
1041:A2
1036:A1
922::
911:EC
905::
858:.
846:.
829:.
817:.
804:.
787:.
775:.
758:.
748:.
738:58
736:.
732:.
715:.
703:11
701:.
697:.
680:.
668:.
651:.
639:.
611:.
601:.
591:21
589:.
585:.
559:.
536:.
526:53
524:.
377:.
356:32
352:18
342:,
330:32
324:20
291::
243:O
235:a
227:)
157:/
2005::
1991:)
1987:(
1978:)
1974:(
1965:)
1961:(
1952:)
1948:(
1939:)
1935:(
1926:)
1922:(
1913:)
1909:(
1733:e
1726:t
1719:v
1646:3
1641:2
1636:1
1594:1
1432:)
1345:)
1341:(
1327:/
1303:1
1291:D
1286:C
1265::
1146:/
1138:(
1046:B
980:/
909:(
895:e
888:t
881:v
866:.
854::
848:8
837:.
825::
795:.
783::
777:8
766:.
744::
723:.
709::
688:.
676::
670:8
659:.
647::
619:.
597::
569:.
544:.
532::
360:2
358:O
354:H
340:4
336:2
333:O
327:H
321:C
241:2
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