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Dysplasia

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404:. Hip dysplasia may occur at birth or develop in early life. Regardless, it does not typically produce symptoms in babies less than a year old. Occasionally one leg may be shorter than the other. The left hip is more often affected than the right. Complications without treatment can include 42: 34: 1595: 374:, resulting in formation of bone that is weak and prone to expansion. As a result, most complications result from fracture, deformity, functional impairment and pain. 554: 503: 115:, and cancerous forms. Various other dysplasias tend to be precancerous. The word's meanings thus cover a spectrum of histopathological variations. 277:
process. The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early,
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do not mature and therefore do not become healthy blood cells. Problems with blood cell formation result in some combination of
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This article is about the precancerous change in cells and tissues. For the clinical condition affecting the hip joint, see
1084: 421: 81: 273:), with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early 1590: 1115: 441:. The kidney consists of irregular cysts of varying sizes. Multicystic dysplastic kidney is a common type of renal 909: 357: 69: 944: 902: 304: 292: 77: 1585: 1554: 1161: 1037: 1001: 939: 498: 91:
senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including
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or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic scale include
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where the socket portion does not fully cover the ball portion, resulting in an increased risk for
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Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with
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Epithelial dysplasia consists of an expansion of immature cells (such as cells of the
88: 584:. In Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJ, Mirzaa G, Amemiya A (eds.). 1574: 1427: 1240: 861: 458: 409: 388: 20: 1529: 1359: 1335: 1325: 1230: 1218: 1211: 802: 612: 214:(reduced functionality of an organ, with decrease in the number or volume of cells) 108: 485: 1517: 1383: 1264: 1259: 1235: 1125: 1065: 924: 887: 810: 581: 367: 325: 217: 196: 172: 156: 92: 41: 1549: 1392: 1388: 1364: 1293: 1274: 1070: 919: 856: 820: 341: 321: 288: 223: 184: 178: 96: 1404: 1347: 1196: 1177: 1089: 975: 960: 825: 739: 712: 677: 405: 397: 274: 229: 190: 166: 144: 100: 61: 33: 27: 658: 649: 633:"Evaluation and Referral for Developmental Dysplasia of the Hip in Infants" 632: 593: 479: 1559: 1354: 1315: 1300: 1223: 1201: 1079: 970: 929: 914: 787: 779: 281: 270: 1432: 1397: 1377: 1254: 1191: 980: 965: 232:(any degenerative disorder resulting from improper or faulty nutrition) 211: 150: 181:(congenital below-average number of cells, especially when inadequate) 851: 783: 442: 434: 329: 317: 104: 52:
is any of various types of abnormal growth or development of cells (
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type are replaced by cells of another mature, differentiated type.
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Boyce AM, Florenzano P, de Castro LF, Collins MT (February 2015).
147:(structural differentiation loss within a cell or group of cells). 40: 32: 815: 363: 1150: 751: 340:. Some types have an increase in immature blood cells, called 107:. An exception is that the myelodysplasias include a range of 1146: 555:"Myelodysplastic Syndromes Treatment (PDQ®)–Patient Version" 433:) is a condition that results from the malformation of the 16:
Abnormal development, at macroscopic or microscopical level
615:. American Academy of Orthopaedic Surgeons. October 2013. 613:"Developmental Dislocation (Dysplasia) of the Hip (DDH)" 362:
Fibrous dysplasia of bone is a disorder where normal
1488: 1413: 1184: 1103: 1056: 1014: 989: 953: 875: 834: 801: 794: 693:Weidner N, Cote R, Suster S, Weiss L, eds. (2003). 588:. Seattle (WA): University of Washington, Seattle. 72:. Dysplasias on a mainly macroscopic scale include 1596:Noninflammatory disorders of female genital tract 208:Abiotrophy (loss in vitality of organ or tissue) 1162: 763: 250: 8: 720:Cotran RS, Kumar V, Collins T, eds. (1999). 582:"Fibrous Dysplasia/McCune–Albright Syndrome" 226:(decrease in the volume of cells or tissues) 220:(increase in the volume of cells or tissues) 1169: 1155: 1147: 798: 770: 756: 748: 626: 624: 622: 257: 243: 133: 648: 549: 547: 545: 607: 605: 603: 504:List of biological development disorders 103:, and dysplasias are thus generally not 724:(6th ed.). London: W.B. Saunders. 514: 136: 673:Multicystic Dysplastic Kidney Imaging 557:. NCI. 12 August 2015. Archived from 7: 722:Robbins Pathologic Basis of Disease 631:Shaw BA, Segal LS (December 2016). 1480:Fluorescence in situ hybridization 199:(development of new cell function) 14: 445:disease, and it is a cause of an 1448:Oral and maxillofacial pathology 465:'bad' or 'difficult' and πλάσις 291:, in which cells of one mature, 153:(organ or part of organ missing) 1: 1085:Clonally transmissible cancer 427:Multicystic dysplastic kidney 422:Multicystic dysplastic kidney 416:Multicystic dysplastic kidney 82:multicystic dysplastic kidney 469:'formation'. The equivalent 1612: 1116:Index of oncology articles 419: 386: 355: 302: 165:(change in cell or tissue 159:(connective tissue growth) 127: 25: 18: 697:. London: W.B. Saunders. 695:Modern Surgical Pathology 523:"Definition of dysplasia" 396:is an abnormality of the 358:Fibrous dysplasia of bone 352:Fibrous dysplasia of bone 310:Myelodysplastic syndromes 187:(conversion in cell type) 70:fibrous dysplasia of bone 344:, in the bone marrow or 305:Myelodysplastic syndrome 299:Myelodysplastic syndrome 193:(abnormal proliferation) 175:(proliferation of cells) 78:myelodysplastic syndrome 26:Not to be confused with 1555:Microbiological culture 1185:Principles of pathology 1038:Prostate cancer staging 1002:Paraneoplastic syndrome 1076:Tumor suppressor genes 1043:Gleason grading system 997:Precancerous condition 650:10.1542/peds.2016-3107 46: 38: 1518:Diagnostic immunology 1343:Programmed cell death 1311:Liquefactive necrosis 1095:Carcinogenic bacteria 835:Malignant progression 338:low white blood cells 87:In one of the modern 44: 37:Normal squamous cells 36: 1513:Medical microbiology 1508:Transfusion medicine 1465:Immunohistochemistry 1415:Anatomical pathology 1306:Coagulative necrosis 1048:Dukes classification 130:Epithelial dysplasia 124:Epithelial dysplasia 66:epithelial dysplasia 60:), and the abnormal 1470:Electron microscopy 1438:Molecular pathology 1316:Gangrenous necrosis 1248:Cellular adaptation 867:Sentinel lymph node 475:classical compounds 473:, in parallel with 330:low red blood cells 137:-plasia and -trophy 1591:Induced stem cells 1498:Clinical chemistry 1490:Clinical pathology 1475:Immunofluorescence 1443:Forensic pathology 1423:Surgical pathology 1331:Fibrinoid necrosis 915:Respiratory system 320:in which immature 47: 39: 1568: 1567: 1535:Mass spectrometry 1144: 1143: 1131:Cancer and nausea 1010: 1009: 847:Carcinoma in situ 731:978-0-7216-7335-6 704:978-0-7216-7253-3 561:on 5 October 2016 439:fetal development 402:joint dislocation 378:Macroscopic scale 370:is replaced with 316:) are a group of 267: 266: 119:Microscopic scale 89:histopathological 58:macroscopic scale 54:microscopic scale 1603: 1455:Gross processing 1321:Caseous necrosis 1171: 1164: 1157: 1148: 945:Endocrine system 910:Digestive system 799: 772: 765: 758: 749: 743: 716: 680: 669: 663: 662: 652: 643:(6): e20163107. 628: 617: 616: 609: 598: 597: 577: 571: 570: 568: 566: 551: 540: 539: 537: 536: 519: 471:surface analysis 259: 252: 245: 134: 45:Dysplastic cells 1611: 1610: 1606: 1605: 1604: 1602: 1601: 1600: 1571: 1570: 1569: 1564: 1523:Immunopathology 1503:Hematopathology 1484: 1409: 1180: 1175: 1145: 1140: 1099: 1052: 1006: 985: 949: 871: 830: 790: 776: 746: 732: 719: 705: 692: 688: 686:Further reading 683: 670: 666: 630: 629: 620: 611: 610: 601: 579: 578: 574: 564: 562: 553: 552: 543: 534: 532: 528:Merriam-Webster 521: 520: 516: 512: 495: 455: 424: 418: 408:, limping, and 391: 385: 380: 360: 354: 307: 301: 263: 132: 126: 121: 31: 24: 17: 12: 11: 5: 1609: 1607: 1599: 1598: 1593: 1588: 1586:Histopathology 1583: 1573: 1572: 1566: 1565: 1563: 1562: 1557: 1552: 1547: 1545:Flow cytometry 1542: 1540:Chromatography 1537: 1532: 1526: 1525: 1520: 1515: 1510: 1505: 1500: 1494: 1492: 1486: 1485: 1483: 1482: 1477: 1472: 1467: 1462: 1460:Histopathology 1457: 1451: 1450: 1445: 1440: 1435: 1430: 1425: 1419: 1417: 1411: 1410: 1408: 1407: 1402: 1401: 1400: 1395: 1386: 1374: 1368: 1367: 1362: 1357: 1352: 1351: 1350: 1340: 1339: 1338: 1333: 1328: 1323: 1318: 1313: 1308: 1298: 1296: 1290: 1289: 1288: 1287: 1282: 1272: 1267: 1262: 1257: 1252: 1250: 1244: 1243: 1238: 1233: 1228: 1227: 1226: 1216: 1215: 1214: 1209: 1204: 1199: 1188: 1186: 1182: 1181: 1176: 1174: 1173: 1166: 1159: 1151: 1142: 1141: 1139: 1138: 1133: 1128: 1123: 1118: 1113: 1107: 1105: 1101: 1100: 1098: 1097: 1092: 1087: 1082: 1073: 1068: 1062: 1060: 1058:Carcinogenesis 1054: 1053: 1051: 1050: 1045: 1040: 1035: 1030: 1024: 1022: 1012: 1011: 1008: 1007: 1005: 1004: 999: 993: 991: 987: 986: 984: 983: 978: 973: 968: 963: 957: 955: 951: 950: 948: 947: 942: 940:Nervous system 937: 932: 927: 922: 917: 912: 907: 906: 905: 903:nasopharyngeal 900: 895: 890: 879: 877: 873: 872: 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1441: 1439: 1436: 1434: 1431: 1429: 1428:Cytopathology 1426: 1424: 1421: 1420: 1418: 1416: 1412: 1406: 1403: 1399: 1396: 1394: 1390: 1387: 1385: 1382: 1381: 1380: 1379: 1375: 1373: 1372:Accumulations 1370: 1369: 1366: 1363: 1361: 1358: 1356: 1353: 1349: 1346: 1345: 1344: 1341: 1337: 1334: 1332: 1329: 1327: 1324: 1322: 1319: 1317: 1314: 1312: 1309: 1307: 1304: 1303: 1302: 1299: 1297: 1295: 1292: 1291: 1286: 1283: 1281: 1278: 1277: 1276: 1273: 1271: 1268: 1266: 1263: 1261: 1258: 1256: 1253: 1251: 1249: 1246: 1245: 1242: 1241:Wound healing 1239: 1237: 1234: 1232: 1229: 1225: 1222: 1221: 1220: 1217: 1213: 1210: 1208: 1205: 1203: 1200: 1198: 1195: 1194: 1193: 1190: 1189: 1187: 1183: 1179: 1172: 1167: 1165: 1160: 1158: 1153: 1152: 1149: 1137: 1134: 1132: 1129: 1127: 1124: 1122: 1119: 1117: 1114: 1112: 1109: 1108: 1106: 1102: 1096: 1093: 1091: 1088: 1086: 1083: 1081: 1077: 1074: 1072: 1069: 1067: 1064: 1063: 1061: 1059: 1055: 1049: 1046: 1044: 1041: 1039: 1036: 1034: 1031: 1029: 1026: 1025: 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399: 395: 394:Hip dysplasia 390: 389:Hip dysplasia 383:Hip dysplasia 382: 377: 375: 373: 369: 365: 359: 351: 349: 347: 343: 339: 335: 334:low platelets 331: 327: 323: 319: 315: 311: 306: 298: 296: 294: 290: 285: 283: 280: 276: 272: 260: 255: 253: 248: 246: 241: 240: 238: 237: 231: 228: 225: 222: 219: 216: 213: 210: 207: 206: 205: 204: 198: 195: 192: 189: 186: 183: 180: 177: 174: 171: 168: 164: 161: 158: 155: 152: 149: 146: 143: 142: 141: 140: 135: 131: 123: 118: 116: 114: 110: 106: 102: 98: 94: 90: 85: 83: 79: 75: 74:hip dysplasia 71: 67: 63: 59: 56:) or organs ( 55: 51: 43: 35: 29: 22: 21:Hip dysplasia 1530:Enzyme assay 1376: 1371: 1360:Karyorrhexis 1336:Myocytolysis 1326:Fat necrosis 1269: 1231:Inflammation 1219:Hemodynamics 1212:Pathogenesis 841: 778:Overview of 721: 694: 671: 667: 640: 636: 586:Gene Reviews 585: 575: 563:. Retrieved 559:the original 533:. Retrieved 526: 517: 499:Pleomorphism 484: 478: 466: 462: 456: 449:in infants. 430: 426: 425: 393: 392: 361: 313: 309: 308: 286: 278: 268: 162: 113:precancerous 86: 49: 48: 1384:Hemosiderin 1265:Hyperplasia 1260:Hypertrophy 1236:Cell damage 1126:Cancer pain 1066:Cancer cell 811:Hyperplasia 326:bone marrow 322:blood cells 218:Hypertrophy 197:Prosoplasia 173:Hyperplasia 157:Desmoplasia 93:hyperplasia 1575:Categories 1550:Blood bank 1393:Lipofuscin 1389:Lipochrome 1365:Karyolysis 1294:Cell death 1275:Metaplasia 1071:Carcinogen 935:Urogenital 876:Topography 857:Metastasis 821:Pseudocyst 795:Conditions 637:Pediatrics 565:27 October 535:2019-09-09 530:dictionary 510:References 289:metaplasia 275:neoplastic 224:Hypotrophy 185:Metaplasia 179:Hypoplasia 97:metaplasia 1405:Steatosis 1348:Apoptosis 1285:Glandular 1270:Dysplasia 1202:Neoplasia 1197:Infection 1178:Pathology 1090:Oncovirus 1080:oncogenes 1033:Ann Arbor 976:Papilloma 961:Carcinoma 954:Histology 898:laryngeal 842:Dysplasia 826:Hamartoma 678:eMedicine 453:Etymology 406:arthritis 398:hip joint 230:Dystrophy 191:Neoplasia 167:phenotype 163:Dysplasia 145:Anaplasia 105:cancerous 101:neoplasia 62:histology 50:Dysplasia 28:Dyscrasia 1581:Oncology 1560:Serology 1355:Pyknosis 1301:Necrosis 1280:Squamous 1224:Ischemia 1111:Research 971:Blastoma 788:oncology 740:39465455 713:50244347 659:27940740 594:25719192 493:See also 282:neoplasm 271:ectoderm 1433:Autopsy 1398:Melanin 1378:pigment 1255:Atrophy 1192:Disease 1121:History 1020:grading 1016:Staging 981:Adenoma 966:Sarcoma 486:-plasia 437:during 324:in the 318:cancers 279:in-situ 212:Atrophy 151:Aplasia 852:Cancer 784:cancer 780:tumors 738:  728:  711:  701:  657:  592:  467:plasis 443:cystic 435:kidney 368:marrow 342:blasts 336:, and 109:benign 99:, and 80:, and 1207:Cause 1104:Misc. 990:Other 930:Blood 477:, is 461:δυσ- 457:From 346:blood 1136:Diet 925:Skin 920:Bone 888:oral 816:Cyst 786:and 736:OCLC 726:ISBN 709:OCLC 699:ISBN 655:PMID 590:PMID 567:2016 480:dys- 463:dys- 431:MCDK 366:and 364:bone 68:and 1028:TNM 676:at 645:doi 641:138 314:MDS 1577:: 782:, 734:. 707:. 653:. 639:. 635:. 621:^ 602:^ 544:^ 525:. 489:. 483:+ 412:. 348:. 332:, 284:. 111:, 95:, 84:. 76:, 1391:/ 1170:e 1163:t 1156:v 1078:/ 1018:/ 771:e 764:t 757:v 742:. 715:. 661:. 647:: 596:. 569:. 538:. 429:( 312:( 258:e 251:t 244:v 169:) 30:. 23:.

Index

Hip dysplasia
Dyscrasia


microscopic scale
macroscopic scale
histology
epithelial dysplasia
fibrous dysplasia of bone
hip dysplasia
myelodysplastic syndrome
multicystic dysplastic kidney
histopathological
hyperplasia
metaplasia
neoplasia
cancerous
benign
precancerous
Epithelial dysplasia
Anaplasia
Aplasia
Desmoplasia
Dysplasia
phenotype
Hyperplasia
Hypoplasia
Metaplasia
Neoplasia
Prosoplasia

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