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Hyperemesis gravidarum

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4067: 5964: 5210: 657: 5234: 5222: 1377:. These erroneous beliefs led to various abusive practices, such as isolating them from their friends and family, or leaving severely ill women to lie in the vomit when they were too weak to clean themselves, which have since been condemned by healthcare professionals and medical organizations such as the College of French Gynecologists and Obstetricians. The 1268:
Vomiting is a common condition affecting about 50% of pregnant women, with another 25% having nausea. However, the incidence of HG is only 0.3–1.5%. After preterm labor, hyperemesis gravidarum is the second most common reason for hospital admission during the first half of pregnancy. Factors such as
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In contrast, infants of women with hyperemesis who have a pregnancy weight gain of more than 7 kilograms (15 lb) appear similar to infants from uncomplicated pregnancies. There is no significant difference in the neonatal death rate in infants born to mothers with HG compared to infants born to
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After IV rehydration is completed, patients typically begin to tolerate frequent small liquid or bland meals. After rehydration, treatment focuses on managing symptoms to allow normal intake of food. However, cycles of hydration and dehydration can occur, making continuing care necessary. Home care
621:(β-hCG). This theory would also explain why hyperemesis gravidarum is most frequently encountered in the first trimester (often around 8–12 weeks of gestation), as β-hCG levels are highest at that time and decline afterward. Another postulated cause of HG is an increase in maternal levels of 644:
are associated with HG. The validation of a second risk variant, rs1054221, provides further support for GDF15's role in the etiology of HG. Additionally, maternal genes appear to play a more significant role than paternal DNA in contributing to the severity of NVP."
309:. HG is estimated to affect 0.3–2.0% of pregnant women, although some sources say the figure can be as high as 3%. While previously known as a common cause of death in pregnancy, with proper treatment this is now very rare. Those affected have a lower risk of 1372:
In previous centuries, the cause was unknown, and various false claims were made, such as the severe vomiting being caused by the woman's rejection of femininity, a manifestation of a subconscious desire to terminate the pregnancy, or being an
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is often thought to have had hyperemesis gravidarum. She died in 1855 while four months pregnant, having been affected by intractable nausea and vomiting throughout her pregnancy, and was unable to tolerate food or even water.
1152:). With respect to effectiveness, it is unknown if one is superior to another for relieving nausea or vomiting. Limited evidence from published clinical trials suggests the use of medications to treat hyperemesis gravidarum. 1104:. A and B vitamins are depleted within two weeks, so extended malnutrition indicates a need for evaluation and supplementation. In addition, electrolyte levels should be monitored and supplemented; of particular concern are 5265: 1052:
are first-line treatments. Due to the potential for severe dehydration and other complications, HG is treated as an emergency. If conservative dietary measures fail, more extensive treatment such as the use of
3113: 640:, a medical researcher whose interest was kindled by her then-doctor telling her that her severe vomiting was "just a ploy to gain sympathy and attention": "Evidence suggests abnormal levels of the hormone 5258: 5969: 3578:
Poon SL (October 2011). "Towards evidence-based emergency medicine: Best BETs from the Manchester Royal Infirmary. BET 2: Steroid therapy in the treatment of intractable hyperemesis gravidarum".
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Though the exact cause of HG is unknown, there are numerous theories. It is thought that HG is caused by a combination of factors, many of which may vary between women, some of which include a
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Hyperemesis gravidarum is estimated to cost US$ 3 billion per year for hospitalization costs alone, not including the direct medical costs of additional outpatient medical appointments,
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In a 2023 study, Fejzo further linked GDF15 as cause when present in high levels due to fetal cell production in contrast with the natural low levels which result maternal sensitivity.
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Diagnosis is usually made based on the observed signs and symptoms. HG has been technically defined as more than three episodes of vomiting per day such that weight loss of 5% or three
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Fejzo M, Rocha N, Cimino I, Lockhart SM, Petry CJ, Kay RG, Burling K, Barker P, George AL, Yasara N, Premawardhena A, Gong S, Cook E, Rimmington D, Rainbow K (13 December 2023).
822:. Criteria for diagnosing HG in a patient generally includes vomiting that results in significant dehydration and weight loss (at least 5% of the patients pre-pregnancy weight). 5523: 1338:, the feminine genitive plural form of an adjective, here used as a noun, meaning "pregnant ". Therefore, hyperemesis gravidarum means "excessive vomiting of pregnant women". 5865: 3109: 442:
and lasts significantly longer than morning sickness. While most women will experience near-complete relief of morning sickness symptoms near the beginning of their
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Bagis T, Gumurdulu Y, Kayaselcuk F, Yilmaz ES, Killicadag E, Tarim E (November 2002). "Endoscopy in hyperemesis gravidarum and Helicobacter pylori infection".
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Aka N, Atalay S, Sayharman S, Kiliç D, Köse G, Küçüközkan T (August 2006). "Leptin and leptin receptor levels in pregnant women with hyperemesis gravidarum".
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approved six research grants to study hyperemesis gravidarum, with a total of US$ 2.1 million dollars in research funding for all six grants combined (an
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caused by HG in the mother. Women with severe hyperemesis who gain less than 7 kilograms (15 lb) during pregnancy tend have newborns with lower
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Deruelle P, Sentilhes L, Ghesquière L, Desbrière R, Ducarme G, Attali L, Jarnoux A, Artzner F, Tranchant A, Schmitz T, Sénat MV (November 2022).
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Women experiencing hyperemesis gravidarum often are dehydrated and lose weight despite efforts to eat. Similar to the onset of standard bouts of
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was hospitalised due to hyperemesis gravidarum during her first pregnancy, and was treated for the same condition during the subsequent two.
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may be beneficial, however, there are some concerns regarding an association with cleft palate, and there is little high-quality data.
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A small percentage rarely vomit, but the nausea still causes most (if not all) of the same issues that hyperemesis with vomiting does.
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products may be helpful, but evidence of effectiveness is limited and inconsistent, though three recent studies support ginger over
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Dodds L, Fell DB, Joseph KS, Allen VM, Butler B (February 2006). "Outcomes of pregnancies complicated by hyperemesis gravidarum".
446:, some people with HG will experience severe symptoms until they give birth to their baby, and sometimes even after giving birth. 5948: 4424: 3297:"Intradialytic hyperalimentation as adjuvant support in pregnant hemodialysis patients: case report and review of the literature" 1230:) may be necessary in certain cases to help maintain volume requirements and allow weight gain. A physician might also prescribe 1167: 598:
mothers who do not have HG. Children born to mothers with undertreated HG have a fourfold increase in neurobehavioral diagnoses.
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While vomiting in pregnancy has been described as early as 2,000 BCE, the first clear medical description of HG was in 1852, by
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Goodwin TM, Montoro M, Mestman JH (September 1992). "Transient hyperthyroidism and hyperemesis gravidarum: clinical aspects".
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Zimmerman CF, Ilstad-Minnihan AB, Bruggeman BS, Bruggeman BJ, Dayton KJ, Joseph N, et al. (2 January 2022).
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may be used if these are not effective. Hospitalization may be required due to the severe symptoms associated.
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Matthews DC, Syed AA (June 2011). "The role of TSH receptor antibodies in the management of Graves' disease".
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Women not responding to IV rehydration and medication may require nutritional support. Patients might receive
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is weak; there is some evidence that corticosteroid use in pregnant women may slightly increase the risk of
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are inactivated in the placenta and may be used in the treatment of hyperemesis gravidarum after 12 weeks.
1120:(PICC) line for hydration and nutrition. Home treatment is often less expensive and reduces the risk for a 432: 5926: 5900: 5678: 5498: 5493: 5442: 5342: 5050: 4918: 4908: 4773: 4496: 4429: 4404: 4340: 1025: 849: 819: 707: 607: 372: 219: 184: 124: 107: 5250: 2339:
Christodoulou-Smith J, Gold JI, Romero R, Goodwin TM, Macgibbon KW, Mullin PM, Fejzo MS (November 2011).
211:. Symptoms often get better after the 20th week of pregnancy but may last the entire pregnancy duration. 5890: 5885: 5337: 5030: 4832: 4636: 4311: 1133: 1066: 953: 579: 364: 356: 1598: 5895: 5764: 5659: 5480: 5455: 5045: 4996: 4316: 4306: 4234: 4229: 4204: 4189: 4184: 2616:"Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid" 1208: 1062: 1017: 948: 831: 536: 1728:
Tan JY, Loh KC, Yeo GS, Chee YC (June 2002). "Transient hyperthyroidism of hyperemesis gravidarum".
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The British Journal of General Practice: The Journal of the Royal College of General Practitioners
2676:"Her Doctor Said Her Illness Was All in Her Head. This Scientist Was Determined to Find the Truth" 841:, the nausea and vomiting with hyperemesis typically starts between 5 and 6 weeks into pregnancy. 431:
in their environment; certain smells may exacerbate symptoms. Excessive salivation, also known as
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The exact causes of hyperemesis gravidarum are unknown. Risk factors include the first pregnancy,
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are present in the urine. Other potential causes of the symptoms should be excluded, including
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Jaques SC, Kingsbury A, Henshcke P, Chomchai C, Clews S, Falconer J, et al. (June 2014).
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McParlin C, O'Donnell A, Robson SC, Beyer F, Moloney E, Bryant A, et al. (October 2016).
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as persistent vomiting frequently leads to a deficiency. Likewise, supplementation for lost
1049: 838: 630: 443: 424: 395: 279: 223: 208: 49: 1287:, and a history of hyperemesis gravidarum have been associated with the development of HG. 5848: 5815: 5604: 5589: 5369: 5025: 4881: 4745: 4703: 4564: 4539: 4463: 4353: 4335: 4281: 4165: 1401: 1280: 1276: 1141: 1037: 1033: 997: 992: 889: 665: 462:
Failure to treat, or inadequate treatment of HG can lead to one or more of the following:
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Tan PC, Omar SZ (April 2011). "Contemporary approaches to hyperemesis during pregnancy".
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Jarvis S, Nelson-Piercy C (June 2011). "Management of nausea and vomiting in pregnancy".
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Zhang Y, Cantor RM, MacGibbon K, Romero R, Goodwin TM, Mullin PM, Fejzo MS (March 2011).
2341:"Posttraumatic stress symptoms following pregnancy complicated by hyperemesis gravidarum" 1298:
was prescribed for treatment of HG in Europe until it was recognized that thalidomide is
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Possible pathophysiological processes involved are summarized in the following table:
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Unknown. New research (late 2023) indicates an elevated level of one specific hormone.
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of HG is unclear, one of the most commonly accepted theory suggests that levels of
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Niebyl JR (October 2010). "Clinical practice. Nausea and vomiting in pregnancy".
3507: 3464: 2485: 2467:"Neurodevelopmental delay in children exposed in utero to hyperemesis gravidarum" 2356: 5759: 5508: 5460: 5393: 5374: 5359: 4925: 4861: 4698: 4641: 4581: 4576: 4414: 4363: 4224: 4034: 4017: 3591: 1361: 1299: 1295: 1249: 1173: 1089: 921: 339: 334: 310: 299: 287: 200: 196: 97: 73: 69: 3872: 3072: 3034: 2846: 2784: 2731: 2631: 2531: 2228: 1883: 1696: 656: 610:. Women with family members who had HG are more likely to develop the disease. 5379: 5286: 5077:
The Convention on the Elimination of All Forms of Discrimination against Women
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Tamay AG, Kuşçu NK (November 2011). "Hyperemesis gravidarum: current aspect".
3312: 3280:(March 2003). "4.6 Drugs used in nausea and vertigo – Vomiting of pregnancy". 2949:
Verberg MF, Gillott DJ, Al-Fardan N, Grudzinskas JG (September–October 2005).
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In 2020, another possible cause of HG was published by a research team led by
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to the hormonal changes of pregnancy, in particular, elevated levels of beta
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Medicinal cannabis has been used to treat pregnancy-associated hyperemesis.
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Ahmed KT, Almashhrawi AA, Rahman RN, Hammoud GM, Ibdah JA (November 2013).
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Summers A (July 2012). "Emergency management of hyperemesis gravidarum".
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The Australian & New Zealand Journal of Obstetrics & Gynaecology
2835:"Extreme morning sickness? Scientists finally pinpoint a possible cause" 2465:
Fejzo MS, Magtira A, Schoenberg FP, Macgibbon K, Mullin PM (June 2015).
1872:"Extreme morning sickness? Scientists finally pinpoint a possible cause" 5622: 5015: 4986: 4962: 4944: 4740: 4720: 2768:"GDF15 linked to maternal risk of nausea and vomiting during pregnancy" 1132:
A number of antiemetics are effective and safe in pregnancy including:
496: 343: 3955: 3446: 3444: 3362: 3110:"Hyperemesis Gravidarum (Severe Nausea and Vomiting During Pregnancy)" 228:
indicated a link between HG and abnormally high levels of the hormone
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Best Practice & Research. Clinical Endocrinology & Metabolism
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European Journal of Obstetrics, Gynecology, and Reproductive Biology
1219:). There is only limited evidence from trials to support the use of 1180:
is also used and relatively well tolerated. Evidence for the use of
3623:"Cannabis, the pregnant woman and her child: weeding out the myths" 2885:"Hyperemesis: Scientists make pregnancy sickness cure breakthrough" 5585: 5556: 5389: 4150: 4101: 1330: 1211:(intravenous feeding via a PICC line) or enteral nutrition (via a 868:(usually accompanied by fever or associated neurological symptoms) 641: 229: 3539:"Motherisk update. Is ondansetron safe for use during pregnancy?" 1396:
such as lost work. In the 15 years between 2007 and 2023, the US
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cancelled the remainder of a tour due to hyperemesis gravidarum.
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is usually performed and blood samples may be taken to check for
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Matthews A, Haas DM, O'Mathúna DP, Dowswell T (September 2015).
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in the infant and may suppress fetal adrenal activity. However,
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Hyperemesis gravidarum tends to occur in the first trimester of
428: 420: 5254: 4038: 4631: 106:, obesity, prior or family history of hyperemesis gravidarum, 3169:"A prospective study of nausea and vomiting during pregnancy" 232:, as well as increased sensitivity to that specific hormone. 5524:
Pruritic urticarial papules and plaques of pregnancy (PUPPP)
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Mullin P, MacGibbon K, Morgan Z, Fejzo M (1 January 2020).
2166:"Liver diseases in pregnancy: diseases unique to pregnancy" 3401:"Interventions for nausea and vomiting in early pregnancy" 2310:"Hyperemesis gravidarum: MedlinePlus Medical Encyclopedia" 3295:
Tuot D, Gibson S, Caughey AB, Frassetto LA (March 2010).
1531:"Managing hyperemesis gravidarum: a multimodal challenge" 1065:
may be needed. For women who require hospital admission,
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Increased levels of sex steroids in hepatic portal system
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When vomiting is severe, it may result in the following:
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Declaration on the elimination of violence against women
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may be needed to know gestational status and to exclude
676:, a hormone that inhibits hunger, may also play a role. 2565:"Biological functions of hCG and hCG-related molecules" 1641:
Goodwin TM (September 2008). "Hyperemesis gravidarum".
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compared with long-term or repeated hospitalizations.
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The Journal of Maternal-Fetal & Neonatal Medicine
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may be required. If oral nutrition is insufficient,
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International Journal of Gynaecology and Obstetrics
2039:. Sudbury, Mass.: Jones and Bartlett. p. 320. 1958:
Nausea and Vomiting : Mechanisms and Treatment
1599:"Hyperemesis gravidarum--assessment and management" 1381:is grassroots network of HG survivors and experts. 166: 150: 139: 123: 113: 96: 88: 80: 55: 39: 34: 2251: 1643:Obstetrics and Gynecology Clinics of North America 1529:Jueckstock JK, Kaestner R, Mylonas I (July 2010). 207:may also occur. It is considered more severe than 5866:Childbirth-related post-traumatic stress disorder 3861:Gynécologie Obstétrique Fertilité & Sénologie 2000:. Cambridge University Press. p. Chapter 6. 1075:measures to prevent the formation of a blood clot 578:The effects of HG on the fetus are mainly due to 266:, and a higher protein diet. Some people require 3254:. U.S. Department of Health and Human Services. 2516:"Familial aggregation of hyperemesis gravidarum" 1922:(6th ed.). Elsevier/Saunders. p. 117. 1919:Obstetrics : normal and problem pregnancies 1681:"Thyroid Storm Caused by Hyperemesis Gravidarum" 1226:to improve outcome. An oversupply of nutrition ( 1170:, some have questioned its effectiveness in HG. 570:of HG, and emotional support can be beneficial. 435:, is another symptom experienced by some women. 427:. Many women with HG are extremely sensitive to 3716:Cherry and Merkatz's complications of pregnancy 3394: 3392: 3390: 3388: 3079:, Treasure Island (FL): StatPearls Publishing, 3041:, Treasure Island (FL): StatPearls Publishing, 2719:American Journal of Obstetrics & Gynecology 1997:Early Pregnancy Issues for the MRCOG and Beyond 1404:of $ 350,000 per grant or $ 140,000 per year). 84:Often gets better but may last entire pregnancy 3453:Current Opinion in Obstetrics & Gynecology 1155:While pyridoxine/doxylamine, a combination of 218:, obesity, prior or family history of HG, and 5266: 4050: 2951:"Hyperemesis gravidarum, a literature review" 2520:American Journal of Obstetrics and Gynecology 2117: 2115: 2078:(1st ed.). Elsevier Mosby. p. 538. 1773:American Journal of Obstetrics and Gynecology 1636: 1634: 945:Thyrotoxicosis (common in Asian subcontinent) 8: 2250:Carlson KJ, Eisenstat SJ, Ziporyn T (2004). 2159: 2157: 2155: 2153: 2113: 2111: 2109: 2107: 2105: 2103: 2101: 2099: 2097: 2095: 3405:The Cochrane Database of Systematic Reviews 2392: 2390: 2388: 2386: 2384: 1592: 1590: 1588: 1586: 1584: 1582: 1580: 1578: 1576: 1475: 1473: 1471: 1469: 1467: 1465: 1463: 1333: 1237:(to prevent Wernicke's encephalopathy) and 1100:) must be considered to reduce the risk of 1032:levels, which are usually raised in HG. An 5438: 5303: 5273: 5259: 5251: 5133:International Center for Research on Women 5064: 4849: 4769: 4612: 4172: 4087: 4057: 4043: 4035: 3946: 3772:"Prince William, Kate expecting 2nd child" 3344: 3342: 3340: 3214: 3212: 3135: 3133: 3131: 2075:Ferri's clinical advisor 2013 5 books in 1 1911: 1909: 1419: 1417: 1283:prior to pregnancy, multiple pregnancies, 31: 3638: 3554: 3424: 3320: 3192: 2966: 2801: 2783: 2730: 2590: 2580: 2539: 2364: 2191: 2181: 1704: 1556: 1546: 1524: 1522: 1520: 1518: 1516: 1514: 1512: 1510: 1508: 1506: 254:Treatment includes drinking fluids and a 2401:. Informa Healthcare. pp. 149–154. 1424:"Management of hyperemesis gravidarum". 854: 681: 655: 317:. Some pregnant women choose to have an 3239:from the original on 11 September 2017. 2254:The New Harvard Guide to Women's Health 1413: 1028:. Hematological investigations include 900:(usually accompanied by abdominal pain) 818:Hyperemesis gravidarum is considered a 799:Increased steroid levels in circulation 3797:Kensington Palace (4 September 2017). 2569:Reproductive Biology and Endocrinology 1118:peripherally inserted central catheter 290:(sold under the brand-name Zofran) or 5504:Intrahepatic cholestasis of pregnancy 5471:Intrahepatic cholestasis of pregnancy 3809:from the original on 4 September 2017 3778:from the original on 8 September 2014 3496:Journal of Obstetrics and Gynaecology 3116:from the original on 15 December 2012 2669: 2667: 2665: 2663: 2661: 2290:from the original on 30 November 2012 2258:. Harvard University Press. pp.  2217:European Journal of Internal Medicine 1491:from the original on 10 December 2015 222:. A December 2023 study published in 7: 5570:Pregnancy-induced hypercoagulability 5221: 5115:Office of Research on Women's Health 3752:from the original on 6 December 2012 3301:International Urology and Nephrology 3258:from the original on 29 October 2013 3148:from the original on 27 January 2013 2747:from the original on 18 January 2023 333:Loss of 5% or more of pre-pregnancy 5233: 5153:Society for Women's Health Research 5087:International Day of the Girl Child 3915:"About Hyperemesis Gravidarum (HG)" 3836:from the original on 28 August 2021 3672:The New England Journal of Medicine 2397:Bourne TH, Condous G, eds. (2006). 2284:"Do I Have Morning Sickness or HG?" 1314:Hyperemesis gravidarum is from the 298:may improve outcomes. Evidence for 5519:Pruritic folliculitis of pregnancy 5197:Birth control in the United States 2694:from the original on 21 March 2023 2503:from the original on 4 March 2016. 2436:10.1097/01.AOG.0000195060.22832.cd 2036:Handbook of home nutrition support 1088:often includes supplementation of 985:Gestational trophoblastic diseases 25: 5777:Pain management during childbirth 5704:Twin-to-twin transfusion syndrome 5092:Commission on the Status of Women 4102:External female genitalia (vulva) 3895:from the original on 27 June 2023 3742:"What is acute morning sickness?" 3250:Office on Women's Health (2010). 3144:. National Institutes of Health. 3091:from the original on 26 July 2023 3053:from the original on 26 July 2023 2646:from the original on 8 March 2021 2320:from the original on 4 March 2021 2170:World Journal of Gastroenterology 2053:from the original on 26 July 2023 2014:from the original on 26 July 2023 1975:from the original on 26 July 2023 1936:from the original on 26 July 2023 1851:from the original on 26 July 2023 1627:from the original on 6 June 2014. 5963: 5962: 5949:Sexual activity during pregnancy 5232: 5220: 5209: 5208: 4425:Assisted reproductive technology 4065: 3925:from the original on 17 May 2023 2920:10.1111/j.1479-828X.2006.00590.x 2399:Handbook of early pregnancy care 1742:10.1111/j.1471-0528.2002.01223.x 1168:nausea and vomiting of pregnancy 187:that is characterized by severe 4391:Breastfeeding and mental health 3828:Southern K (23 February 2019). 2136:10.7748/en2012.07.20.4.24.c9206 1063:intravenous nutritional support 790:Gastroesophageal reflux disease 590:. They also tend to give birth 270:. With respect to medications, 5451:Acute fatty liver of pregnancy 3417:10.1002/14651858.CD007575.pub4 1432:(11): 126–129. November 2013. 1426:Drug and Therapeutics Bulletin 1116:is available in the form of a 1012:Common investigations include 830:, electrolyte imbalances, and 564:post-traumatic stress disorder 407:Symptoms can be aggravated by 260:electrolyte-replacement drinks 258:. Recommendations may include 1: 5653:Prelabor rupture of membranes 5041:Social determinants of health 3071:Jennings LK, Mahdy H (2023), 3033:Jennings LK, Mahdy H (2023), 3004:10.1016/s0020-7292(02)00230-8 1785:10.1016/s0002-9378(11)91565-8 1398:National Institutes of Health 633:leading to nausea/vomiting). 419:(especially those containing 384:imbalances such as metabolic 143:Drinking fluids, bland diet, 5932:Systemic lupus erythematosus 5583:Maternal care related to the 5565:Gestational thrombocytopenia 5036:Gender disparities in health 4374:Mother-to-child transmission 3508:10.3109/01443615.2011.611918 3465:10.1097/GCO.0b013e328342d208 2674:Callahan A (14 March 2023). 2486:10.1016/j.ejogrb.2015.03.028 2357:10.3109/14767058.2011.582904 1597:Sheehan P (September 2007). 1355:Catherine, Princess of Wales 1071:low-molecular-weight heparin 1057:medications and intravenous 1040:or partial molar pregnancy. 619:human chorionic gonadotropin 487:central pontine myelinolysis 5733:Cephalopelvic disproportion 4649:Pelvic inflammatory disease 4592:Hormone replacement therapy 4156:Reproductive system disease 3592:10.1136/emermed-2011-200636 2833:Wong C (13 December 2023). 1870:Wong C (13 December 2023). 1606:Australian Family Physician 1122:hospital-acquired infection 987:(rule out with urine β-hCG) 898:Gastrointestinal disorders 588:smaller for gestational age 6018: 5992:Health issues in pregnancy 5844:Breastfeeding difficulties 5643:Constriction ring syndrome 5617:Braxton Hicks contractions 5143:Black Women's Health Study 4210:Complications of pregnancy 3873:10.1016/j.gofs.2022.09.002 3740:McSweeny L (3 June 2010). 3580:Emergency Medicine Journal 3278:British National Formulary 3112:. Cleveland Clinic. 2012. 2847:10.1038/d41586-023-03982-8 2785:10.1038/s41586-023-06921-9 2732:10.1016/j.ajog.2019.11.098 2632:10.1016/j.beem.2004.03.010 2532:10.1016/j.ajog.2010.09.018 2229:10.1016/j.ejim.2011.02.006 1884:10.1038/d41586-023-03982-8 1697:10.1016/j.aace.2021.12.005 1685:AACE Clinical Case Reports 1375:attention-seeking behavior 1186:cleft lip and cleft palate 1086:Intravenous (IV) hydration 765:lower esophageal sphincter 402:activities of daily living 5957: 5881:Peripartum cardiomyopathy 5871:Pubic symphysis diastasis 5204: 5120:Women's Health Initiative 4973:Major depressive disorder 4801:Intimate partner violence 4662:Female genital mutilation 4657: 4349: 3543:Canadian Family Physician 3313:10.1007/s11255-009-9671-5 3252:"Pregnancy Complications" 2955:Human Reproduction Update 2614:Hershman JM (June 2004). 2424:Obstetrics and Gynecology 1961:. Springer. p. 152. 1655:10.1016/j.ogc.2008.04.002 1321:, meaning excessive, and 1279:production, low age, low 1102:Wernicke's encephalopathy 850:Diagnoses to be ruled out 804:lower esophagal sphincter 592:before 37 weeks gestation 477:Wernicke's encephalopathy 5407:Gestational hypertension 4709:Gynaecological disorders 4525:Culture and menstruation 4492:Contraceptive prevalence 4384:Compulsory sterilization 3537:Koren G (October 2012). 3142:"Hyperemesis gravidarum" 3073:"Hyperemesis Gravidarum" 3035:"Hyperemesis Gravidarum" 2183:10.3748/wjg.v19.i43.7639 1485:Office on Women's Health 1438:10.1136/dtb.2013.11.0215 1067:thromboembolic stockings 1016:(BUN) and electrolytes, 672:are associated with it. 5806:Umbilical cord prolapse 5728:Amniotic fluid embolism 5486:dermatoses of pregnancy 4992:Urinary tract infection 4784:Abuse during childbirth 3627:Journal of Perinatology 2582:10.1186/1477-7827-8-102 2563:Cole LA (August 2010). 1829:10.1001/jama.2016.14337 932:Small bowel obstruction 875:Urinary tract infection 861:Differential diagnoses 852:include the following: 394:Physical and emotional 369:(pyridoxine) deficiency 245:urinary tract infection 130:Urinary tract infection 5922:Concomitant conditions 5901:Postpartum thyroiditis 5679:Circumvallate placenta 5499:Impetigo herpetiformis 5494:Gestational pemphigoid 5466:Hyperemesis gravidarum 5399:hypertensive disorders 4909:Cardiovascular disease 4497:Contraceptive security 4430:In vitro fertilization 4341:Postpartum confinement 4215:Hyperemesis gravidarum 3713:Cohen WR, ed. (2000). 3219:Evans AT, ed. (2007). 1548:10.1186/1741-7015-8-46 1334: 1026:thyroid function tests 845:Differential diagnosis 820:diagnosis of exclusion 777:Gastrointestinal tract 754:Decreased gut mobility 716:, causing gestational 708:gastrointestinal tract 661: 608:genetic predisposition 580:electrolyte imbalances 377:(cobalamin) deficiency 220:trophoblastic disorder 185:pregnancy complication 177:Hyperemesis gravidarum 125:Differential diagnosis 108:trophoblastic disorder 35:Hyperemesis gravidarum 5891:Postpartum infections 5886:Postpartum depression 5031:Healthcare inequality 4833:Gender discrimination 4637:Human papilloma virus 4312:Vesicovaginal fistula 3684:10.1056/NEJMcp1003896 3140:Medline Plus (2012). 2968:10.1093/humupd/dmi021 2286:. H.E.R. Foundation. 1487:. 27 September 2010. 1134:pyridoxine/doxylamine 954:Diabetic ketoacidosis 832:complete blood counts 659: 566:are common secondary 433:sialorrhea gravidarum 361:(thiamine) deficiency 353:Nutritional disorders 313:but a higher risk of 170:~1% of pregnant women 5896:Postpartum psychosis 5765:Obstetrical bleeding 5660:Obstetrical bleeding 5481:Integumentary system 5456:Gestational diabetes 5435:related to pregnancy 5433:Other, predominantly 5138:Nurses' Health Study 5046:Reproductive justice 4997:Urinary incontinence 4617:Sexually transmitted 4472:Intrauterine devices 4317:Rectovaginal fistula 4307:Obstetrical fistulae 4235:Gestational diabetes 4230:Obstetrical bleeding 4205:Adolescent pregnancy 4190:Gravidity and parity 4185:Unintended pregnancy 3774:. 8 September 2014. 3222:Manual of obstetrics 2526:(3): 230.e1–230.e7. 1245:Alternative medicine 1209:parenteral nutrition 1048:Dry, bland food and 1018:liver function tests 537:deep vein thrombosis 321:due to HG symptoms. 5876:Postpartum bleeding 5699:Placental abruption 5684:Monochorionic twins 5514:Prurigo gestationis 5051:Women's empowerment 4919:Alzheimer's disease 4550:Cloth menstrual pad 4507:Fertility awareness 4477:Oral contraceptives 4359:Perinatal mortality 3640:10.1038/jp.2013.180 2430:(2 Pt 1): 285–292. 2033:DeLegge MH (2007). 1649:(3): 401–17, viii. 1368:Society and culture 1272:Helicobacter pylori 1203:Nutritional support 1014:blood urea nitrogen 959:Hyperparathyroidism 784:Helicobacter pylori 627:intestinal motility 502:Mallory–Weiss tears 307:Paul Antoine Dubois 134:high thyroid levels 5906:Puerperal mastitis 5861:Breast engorgement 5648:Monoamniotic twins 5638:Chorionic hematoma 5148:Cartwright Inquiry 5059:Politics, research 4877:Endometrial cancer 4731:Sexual intercourse 4502:Planned parenthood 4487:Male contraceptive 4009:External resources 2887:. 13 December 2023 2680:The New York Times 1386:prescription drugs 1302:and is a cause of 1166:, is effective in 1081:Intravenous fluids 706:Distention of the 662: 542:pulmonary embolism 325:Signs and symptoms 268:intravenous fluids 249:overactive thyroid 216:multiple pregnancy 145:intravenous fluids 104:multiple pregnancy 5979: 5978: 5937:Thyroid disorders 5927:Diabetes mellitus 5811:Uterine inversion 5743:Shoulder dystocia 5738:Obstructed labour 5714: 5713: 5578: 5577: 5547:Chorea gravidarum 5323:Ectopic pregnancy 5248: 5247: 5128: 5127: 4953: 4952: 4904: 4903: 4887:Papanicolaou test 4843:Non-communicable 4811:Sexual harassment 4789:Domestic violence 4759: 4758: 4602: 4601: 4399: 4398: 4302:Retained placenta 4220:Ectopic pregnancy 4032: 4031: 3726:978-0-683-01673-4 3678:(16): 1544–1550. 3549:(10): 1092–1093. 3363:10.1136/bmj.d3606 3232:978-0-7817-9696-5 2778:(7996): 760–767. 2408:978-1-84214-323-0 2351:(11): 1307–1311. 2269:978-0-674-01343-8 2176:(43): 7639–7646. 2085:978-0-323-08373-7 2072:Ferri FF (2012). 2046:978-0-7637-4769-5 2007:978-1-107-71799-2 1968:978-3-642-70479-6 1955:Davis CJ (1986). 1929:978-1-4377-1935-2 1916:Gabbe SG (2012). 1823:(13): 1392–1401. 1285:molar pregnancies 1228:hyperalimentation 1005: 1004: 949:Addison's disease 811: 810: 613:One factor is an 554:cerebral arteries 522:pneumomediastinum 417:prenatal vitamins 239:has occurred and 174: 173: 119:Based on symptoms 115:Diagnostic method 102:First pregnancy, 29:Medical condition 16:(Redirected from 6009: 5966: 5965: 5801:Postmature birth 5789:Placenta accreta 5694:Placenta praevia 5689:Placenta accreta 5633:Chorioamnionitis 5443:Digestive system 5439: 5365:Fetal resorption 5353:Rudimentary horn 5310:abortive outcome 5304: 5275: 5268: 5261: 5252: 5236: 5235: 5224: 5223: 5212: 5211: 5065: 4850: 4770: 4764:Non-reproductive 4613: 4530:Feminine hygiene 4297:Cesarian section 4292:Obstructed labor 4173: 4088: 4069: 4059: 4052: 4045: 4036: 3947: 3935: 3934: 3932: 3930: 3911: 3905: 3904: 3902: 3900: 3852: 3846: 3845: 3843: 3841: 3825: 3819: 3818: 3816: 3814: 3803:@KensingtonRoyal 3794: 3788: 3787: 3785: 3783: 3768: 3762: 3761: 3759: 3757: 3737: 3731: 3730: 3710: 3704: 3703: 3667: 3661: 3660: 3642: 3618: 3612: 3611: 3575: 3569: 3568: 3558: 3534: 3528: 3527: 3491: 3485: 3484: 3448: 3439: 3438: 3428: 3396: 3383: 3382: 3346: 3335: 3334: 3324: 3292: 3286: 3285: 3274: 3268: 3267: 3265: 3263: 3247: 3241: 3240: 3216: 3207: 3206: 3196: 3179:(371): 245–248. 3164: 3158: 3157: 3155: 3153: 3137: 3126: 3125: 3123: 3121: 3106: 3100: 3099: 3098: 3096: 3068: 3062: 3061: 3060: 3058: 3030: 3024: 3023: 2987: 2981: 2980: 2970: 2946: 2940: 2939: 2903: 2897: 2896: 2894: 2892: 2881: 2875: 2874: 2830: 2824: 2823: 2805: 2787: 2763: 2757: 2756: 2754: 2752: 2734: 2710: 2704: 2703: 2701: 2699: 2671: 2656: 2655: 2653: 2651: 2611: 2605: 2604: 2594: 2584: 2560: 2554: 2553: 2543: 2511: 2505: 2504: 2502: 2471: 2462: 2456: 2455: 2419: 2413: 2412: 2394: 2379: 2378: 2368: 2336: 2330: 2329: 2327: 2325: 2306: 2300: 2299: 2297: 2295: 2280: 2274: 2273: 2257: 2247: 2241: 2240: 2212: 2206: 2205: 2195: 2185: 2161: 2148: 2147: 2119: 2090: 2089: 2069: 2063: 2062: 2060: 2058: 2030: 2024: 2023: 2021: 2019: 1994:Kumar G (2011). 1991: 1985: 1984: 1982: 1980: 1952: 1946: 1945: 1943: 1941: 1913: 1904: 1903: 1867: 1861: 1860: 1858: 1856: 1808: 1797: 1796: 1768: 1762: 1761: 1725: 1719: 1718: 1708: 1676: 1667: 1666: 1638: 1629: 1628: 1626: 1603: 1594: 1571: 1570: 1560: 1550: 1526: 1501: 1500: 1498: 1496: 1477: 1458: 1457: 1421: 1390:home health care 1348:Charlotte Brontë 1337: 1217:nasojejunal tube 1213:nasogastric tube 1050:oral rehydration 977:Iron supplements 855: 839:morning sickness 802:Relaxing of the 691:Pathophysiology 682: 660:Morning sickness 631:gastric emptying 615:adverse reaction 546:splenic avulsion 444:second trimester 400:Difficulty with 280:Prochlorperazine 209:morning sickness 50:Gastroenterology 32: 21: 6017: 6016: 6012: 6011: 6010: 6008: 6007: 6006: 5982: 5981: 5980: 5975: 5953: 5910: 5854:Cracked nipples 5849:Low milk supply 5830: 5816:Uterine rupture 5710: 5605:Oligohydramnios 5590:amniotic cavity 5584: 5574: 5551: 5533: 5484: 5475: 5434: 5428: 5397: 5384: 5370:Molar pregnancy 5309: 5293: 5279: 5249: 5244: 5200: 5185:Family planning 5163: 5157: 5124: 5101: 5060: 5054: 5026:Gender equality 5009: 5003: 4949: 4900: 4882:Cervical cancer 4844: 4837: 4775: 4765: 4755: 4746:Sex differences 4704:Forced marriage 4653: 4618: 4608: 4598: 4540:Menstrual cycle 4511: 4464:Family planning 4462: 4453: 4406: 4395: 4354:Maternal deaths 4345: 4336:Postpartum care 4282:Multiple births 4258: 4167: 4160: 4093: 4084: 4081: 4073: 4063: 4033: 4028: 4027: 4004: 4003: 3958: 3944: 3939: 3938: 3928: 3926: 3913: 3912: 3908: 3898: 3896: 3867:(11): 700–711. 3854: 3853: 3849: 3839: 3837: 3827: 3826: 3822: 3812: 3810: 3796: 3795: 3791: 3781: 3779: 3770: 3769: 3765: 3755: 3753: 3739: 3738: 3734: 3727: 3712: 3711: 3707: 3669: 3668: 3664: 3620: 3619: 3615: 3586:(10): 898–900. 3577: 3576: 3572: 3536: 3535: 3531: 3493: 3492: 3488: 3450: 3449: 3442: 3411:(9): CD007575. 3398: 3397: 3386: 3348: 3347: 3338: 3294: 3293: 3289: 3276: 3275: 3271: 3261: 3259: 3249: 3248: 3244: 3233: 3218: 3217: 3210: 3166: 3165: 3161: 3151: 3149: 3139: 3138: 3129: 3119: 3117: 3108: 3107: 3103: 3094: 3092: 3070: 3069: 3065: 3056: 3054: 3032: 3031: 3027: 2989: 2988: 2984: 2948: 2947: 2943: 2905: 2904: 2900: 2890: 2888: 2883: 2882: 2878: 2832: 2831: 2827: 2765: 2764: 2760: 2750: 2748: 2712: 2711: 2707: 2697: 2695: 2673: 2672: 2659: 2649: 2647: 2613: 2612: 2608: 2562: 2561: 2557: 2513: 2512: 2508: 2500: 2469: 2464: 2463: 2459: 2421: 2420: 2416: 2409: 2396: 2395: 2382: 2338: 2337: 2333: 2323: 2321: 2314:medlineplus.gov 2308: 2307: 2303: 2293: 2291: 2282: 2281: 2277: 2270: 2249: 2248: 2244: 2214: 2213: 2209: 2163: 2162: 2151: 2124:Emergency Nurse 2121: 2120: 2093: 2086: 2071: 2070: 2066: 2056: 2054: 2047: 2032: 2031: 2027: 2017: 2015: 2008: 1993: 1992: 1988: 1978: 1976: 1969: 1954: 1953: 1949: 1939: 1937: 1930: 1915: 1914: 1907: 1869: 1868: 1864: 1854: 1852: 1810: 1809: 1800: 1770: 1769: 1765: 1727: 1726: 1722: 1678: 1677: 1670: 1640: 1639: 1632: 1624: 1601: 1596: 1595: 1574: 1528: 1527: 1504: 1494: 1492: 1479: 1478: 1461: 1423: 1422: 1415: 1410: 1370: 1344: 1312: 1293: 1281:body mass index 1277:thyroid hormone 1269:infection with 1266: 1247: 1235: 1224: 1205: 1182:corticosteroids 1160: 1142:diphenhydramine 1130: 1099: 1083: 1073:may be used as 1046: 1034:ultrasound scan 1010: 998:Choriocarcinoma 993:Molar pregnancy 901: 890:Gastroenteritis 869: 847: 816: 712:Crossover with 666:pathophysiology 654: 652:Pathophysiology 604: 576: 460: 455: 376: 368: 360: 327: 315:premature birth 292:corticosteroids 278:are preferred. 199:, and possibly 48: 30: 23: 22: 15: 12: 11: 5: 6015: 6013: 6005: 6004: 6002:Women's health 5999: 5994: 5984: 5983: 5977: 5976: 5974: 5973: 5958: 5955: 5954: 5952: 5951: 5946: 5944:Maternal death 5941: 5940: 5939: 5934: 5929: 5918: 5916: 5912: 5911: 5909: 5908: 5903: 5898: 5893: 5888: 5883: 5878: 5873: 5868: 5863: 5858: 5857: 5856: 5851: 5840: 5838: 5832: 5831: 5829: 5828: 5823: 5818: 5813: 5808: 5803: 5798: 5793: 5792: 5791: 5779: 5774: 5773: 5772: 5762: 5757: 5752: 5750:Fetal distress 5747: 5746: 5745: 5735: 5730: 5724: 5722: 5716: 5715: 5712: 5711: 5709: 5708: 5707: 5706: 5701: 5696: 5691: 5686: 5681: 5669: 5668: 5667: 5657: 5656: 5655: 5650: 5645: 5640: 5635: 5619: 5614: 5613: 5612: 5610:Polyhydramnios 5607: 5599:amniotic fluid 5594: 5592: 5580: 5579: 5576: 5575: 5573: 5572: 5567: 5561: 5559: 5553: 5552: 5550: 5549: 5543: 5541: 5539:Nervous system 5535: 5534: 5532: 5531: 5526: 5521: 5516: 5511: 5506: 5501: 5496: 5490: 5488: 5477: 5476: 5474: 5473: 5468: 5463: 5458: 5453: 5447: 5445: 5436: 5430: 5429: 5427: 5426: 5421: 5420: 5419: 5417:HELLP syndrome 5409: 5403: 5401: 5386: 5385: 5383: 5382: 5377: 5372: 5367: 5362: 5357: 5356: 5355: 5350: 5345: 5340: 5335: 5330: 5320: 5314: 5312: 5308:Pregnancy with 5301: 5295: 5294: 5280: 5278: 5277: 5270: 5263: 5255: 5246: 5245: 5243: 5242: 5230: 5218: 5205: 5202: 5201: 5199: 5194: 5189: 5188: 5187: 5177: 5172: 5167: 5165: 5162:Women's health 5159: 5158: 5156: 5155: 5150: 5145: 5140: 5135: 5129: 5126: 5125: 5123: 5122: 5117: 5111: 5109: 5103: 5102: 5100: 5099: 5094: 5089: 5084: 5079: 5073: 5071: 5069:United Nations 5062: 5061:& advocacy 5056: 5055: 5053: 5048: 5043: 5038: 5033: 5028: 5023: 5018: 5013: 5011: 5008:Sociocultural 5005: 5004: 5002: 5001: 5000: 4999: 4994: 4989: 4979: 4978: 4977: 4976: 4975: 4965: 4954: 4951: 4950: 4948: 4947: 4942: 4941: 4940: 4939: 4938: 4923: 4922: 4921: 4911: 4905: 4902: 4901: 4899: 4898: 4896:Ovarian cancer 4893: 4892: 4891: 4890: 4889: 4879: 4872:Uterine cancer 4869: 4864: 4858: 4856: 4847: 4839: 4838: 4836: 4835: 4830: 4825: 4824: 4823: 4816:Sexual assault 4813: 4808: 4803: 4798: 4797: 4796: 4786: 4780: 4778: 4767: 4761: 4760: 4757: 4756: 4754: 4753: 4748: 4743: 4738: 4733: 4728: 4723: 4718: 4717: 4716: 4706: 4701: 4696: 4694:Child marriage 4691: 4689:Breast ironing 4686: 4681: 4679:Breast binding 4676: 4675: 4674: 4669: 4667:Clitoridectomy 4658: 4655: 4654: 4652: 4651: 4646: 4645: 4644: 4634: 4629: 4623: 4621: 4610: 4604: 4603: 4600: 4599: 4597: 4596: 4595: 4594: 4584: 4579: 4574: 4569: 4568: 4567: 4562: 4557: 4552: 4545:Menstrual aids 4542: 4537: 4532: 4527: 4521: 4519: 4513: 4512: 4510: 4509: 4504: 4499: 4494: 4489: 4484: 4479: 4474: 4468: 4466: 4455: 4454: 4452: 4451: 4450: 4449: 4444: 4434: 4433: 4432: 4427: 4422: 4411: 4409: 4401: 4400: 4397: 4396: 4394: 4393: 4388: 4387: 4386: 4376: 4371: 4366: 4361: 4356: 4350: 4347: 4346: 4344: 4343: 4338: 4333: 4332: 4331: 4329:Husband stitch 4321: 4320: 4319: 4314: 4304: 4299: 4294: 4289: 4284: 4279: 4274: 4268: 4266: 4260: 4259: 4257: 4256: 4255: 4254: 4253: 4252: 4247: 4237: 4232: 4227: 4222: 4217: 4207: 4202: 4200:Antenatal care 4197: 4192: 4187: 4181: 4179: 4170: 4162: 4161: 4159: 4158: 4153: 4148: 4146:Fallopian tube 4143: 4138: 4133: 4128: 4127: 4126: 4121: 4116: 4115: 4114: 4098: 4096: 4092:Reproductive 4085: 4078: 4075: 4074: 4071:Women's health 4064: 4062: 4061: 4054: 4047: 4039: 4030: 4029: 4026: 4025: 4013: 4012: 4010: 4006: 4005: 4002: 4001: 3990: 3975: 3959: 3954: 3953: 3951: 3950:Classification 3943: 3942:External links 3940: 3937: 3936: 3919:HER Foundation 3906: 3847: 3820: 3789: 3763: 3732: 3725: 3705: 3662: 3633:(6): 417–424. 3613: 3570: 3529: 3502:(8): 708–712. 3486: 3440: 3384: 3336: 3307:(1): 233–237. 3287: 3284:(45 ed.). 3269: 3242: 3231: 3208: 3159: 3127: 3101: 3063: 3025: 2998:(2): 105–109. 2982: 2961:(5): 527–539. 2941: 2914:(4): 274–277. 2898: 2876: 2825: 2758: 2705: 2657: 2626:(2): 249–265. 2606: 2555: 2506: 2457: 2414: 2407: 2380: 2331: 2301: 2275: 2268: 2242: 2223:(3): 213–216. 2207: 2149: 2091: 2084: 2064: 2045: 2025: 2006: 1986: 1967: 1947: 1928: 1905: 1862: 1798: 1779:(3): 648–652. 1763: 1736:(6): 683–688. 1720: 1691:(3): 124–127. 1668: 1630: 1612:(9): 698–701. 1572: 1502: 1459: 1412: 1411: 1409: 1406: 1394:indirect costs 1379:HER Foundation 1369: 1366: 1343: 1340: 1311: 1308: 1292: 1289: 1265: 1262: 1246: 1243: 1233: 1222: 1204: 1201: 1190:hydrocortisone 1178:Metoclopramide 1158: 1146:phenothiazines 1138:antihistamines 1129: 1126: 1097: 1082: 1079: 1045: 1042: 1009: 1008:Investigations 1006: 1003: 1002: 1001: 1000: 995: 988: 981: 980: 979: 978: 975: 968: 964: 963: 962: 961: 956: 951: 946: 941: 937: 936: 935: 934: 929: 924: 919: 914: 909: 902: 899: 895: 894: 893: 892: 887: 882: 877: 870: 867: 863: 862: 859: 846: 843: 815: 812: 809: 808: 807: 806: 800: 795: 794: 793: 787: 778: 774: 773: 772: 771: 768: 761: 755: 750: 749: 748: 743: 736: 735: 734: 729: 723: 722: 721: 720: 718:thyrotoxicosis 710: 702: 699: 693: 692: 689: 686: 653: 650: 603: 600: 575: 572: 557: 556: 547: 544: 539: 534: 532:deconditioning 529: 527:rhabdomyolysis 524: 519: 514: 509: 504: 499: 494: 489: 484: 482:kidney failure 479: 474: 469: 459: 458:Pregnant woman 456: 454: 451: 405: 404: 398: 392: 390:thyrotoxicosis 379: 374: 366: 358: 350: 337: 326: 323: 284:dimenhydrinate 276:metoclopramide 172: 171: 168: 164: 163: 161:metoclopramide 154: 148: 147: 141: 137: 136: 127: 121: 120: 117: 111: 110: 100: 94: 93: 90: 86: 85: 82: 78: 77: 59: 53: 52: 43: 37: 36: 28: 24: 14: 13: 10: 9: 6: 4: 3: 2: 6014: 6003: 6000: 5998: 5995: 5993: 5990: 5989: 5987: 5972: 5971: 5967: 5960: 5959: 5956: 5950: 5947: 5945: 5942: 5938: 5935: 5933: 5930: 5928: 5925: 5924: 5923: 5920: 5919: 5917: 5913: 5907: 5904: 5902: 5899: 5897: 5894: 5892: 5889: 5887: 5884: 5882: 5879: 5877: 5874: 5872: 5869: 5867: 5864: 5862: 5859: 5855: 5852: 5850: 5847: 5846: 5845: 5842: 5841: 5839: 5837: 5833: 5827: 5826:Uterine atony 5824: 5822: 5819: 5817: 5814: 5812: 5809: 5807: 5804: 5802: 5799: 5797: 5796:Preterm birth 5794: 5790: 5787: 5786: 5785: 5784: 5780: 5778: 5775: 5771: 5768: 5767: 5766: 5763: 5761: 5758: 5756: 5753: 5751: 5748: 5744: 5741: 5740: 5739: 5736: 5734: 5731: 5729: 5726: 5725: 5723: 5721: 5717: 5705: 5702: 5700: 5697: 5695: 5692: 5690: 5687: 5685: 5682: 5680: 5677: 5676: 5675: 5674: 5670: 5666: 5663: 5662: 5661: 5658: 5654: 5651: 5649: 5646: 5644: 5641: 5639: 5636: 5634: 5631: 5630: 5629: 5628: 5624: 5620: 5618: 5615: 5611: 5608: 5606: 5603: 5602: 5601: 5600: 5596: 5595: 5593: 5591: 5587: 5581: 5571: 5568: 5566: 5563: 5562: 5560: 5558: 5554: 5548: 5545: 5544: 5542: 5540: 5536: 5530: 5529:Stretch marks 5527: 5525: 5522: 5520: 5517: 5515: 5512: 5510: 5507: 5505: 5502: 5500: 5497: 5495: 5492: 5491: 5489: 5487: 5482: 5478: 5472: 5469: 5467: 5464: 5462: 5459: 5457: 5454: 5452: 5449: 5448: 5446: 5444: 5440: 5437: 5431: 5425: 5422: 5418: 5415: 5414: 5413: 5412:Pre-eclampsia 5410: 5408: 5405: 5404: 5402: 5400: 5395: 5391: 5387: 5381: 5378: 5376: 5373: 5371: 5368: 5366: 5363: 5361: 5358: 5354: 5351: 5349: 5346: 5344: 5341: 5339: 5336: 5334: 5331: 5329: 5326: 5325: 5324: 5321: 5319: 5316: 5315: 5313: 5311: 5305: 5302: 5300: 5296: 5292: 5288: 5284: 5281:Pathology of 5276: 5271: 5269: 5264: 5262: 5257: 5256: 5253: 5241: 5240: 5231: 5229: 5228: 5219: 5217: 5216: 5207: 5206: 5203: 5198: 5195: 5193: 5190: 5186: 5183: 5182: 5181: 5178: 5176: 5173: 5171: 5168: 5166: 5160: 5154: 5151: 5149: 5146: 5144: 5141: 5139: 5136: 5134: 5131: 5130: 5121: 5118: 5116: 5113: 5112: 5110: 5108: 5107:United States 5104: 5098: 5095: 5093: 5090: 5088: 5085: 5083: 5080: 5078: 5075: 5074: 5072: 5070: 5066: 5063: 5057: 5052: 5049: 5047: 5044: 5042: 5039: 5037: 5034: 5032: 5029: 5027: 5024: 5022: 5021:Disadvantaged 5019: 5017: 5014: 5012: 5006: 4998: 4995: 4993: 4990: 4988: 4985: 4984: 4983: 4982:Urinary tract 4980: 4974: 4971: 4970: 4969: 4966: 4964: 4961: 4960: 4959: 4958:Mental health 4956: 4955: 4946: 4943: 4937: 4934: 4933: 4932: 4929: 4928: 4927: 4924: 4920: 4917: 4916: 4915: 4912: 4910: 4907: 4906: 4897: 4894: 4888: 4885: 4884: 4883: 4880: 4878: 4875: 4874: 4873: 4870: 4868: 4867:Breast cancer 4865: 4863: 4860: 4859: 4857: 4855: 4851: 4848: 4846: 4840: 4834: 4831: 4829: 4826: 4822: 4819: 4818: 4817: 4814: 4812: 4809: 4807: 4804: 4802: 4799: 4795: 4792: 4791: 4790: 4787: 4785: 4782: 4781: 4779: 4777: 4776:against women 4771: 4768: 4762: 4752: 4751:Sex education 4749: 4747: 4744: 4742: 4739: 4737: 4734: 4732: 4729: 4727: 4724: 4722: 4719: 4715: 4712: 4711: 4710: 4707: 4705: 4702: 4700: 4697: 4695: 4692: 4690: 4687: 4685: 4684:Breast health 4682: 4680: 4677: 4673: 4670: 4668: 4665: 4664: 4663: 4660: 4659: 4656: 4650: 4647: 4643: 4640: 4639: 4638: 4635: 4633: 4630: 4628: 4625: 4624: 4622: 4620: 4614: 4611: 4605: 4593: 4590: 4589: 4588: 4585: 4583: 4580: 4578: 4575: 4573: 4570: 4566: 4563: 4561: 4558: 4556: 4555:Menstrual cup 4553: 4551: 4548: 4547: 4546: 4543: 4541: 4538: 4536: 4533: 4531: 4528: 4526: 4523: 4522: 4520: 4518: 4514: 4508: 4505: 4503: 4500: 4498: 4495: 4493: 4490: 4488: 4485: 4483: 4480: 4478: 4475: 4473: 4470: 4469: 4467: 4465: 4460: 4459:Contraception 4456: 4448: 4445: 4443: 4440: 4439: 4438: 4435: 4431: 4428: 4426: 4423: 4421: 4420:Childlessness 4418: 4417: 4416: 4413: 4412: 4410: 4408: 4405:Reproductive 4402: 4392: 4389: 4385: 4382: 4381: 4380: 4379:Sterilization 4377: 4375: 4372: 4370: 4367: 4365: 4362: 4360: 4357: 4355: 4352: 4351: 4348: 4342: 4339: 4337: 4334: 4330: 4327: 4326: 4325: 4322: 4318: 4315: 4313: 4310: 4309: 4308: 4305: 4303: 4300: 4298: 4295: 4293: 4290: 4288: 4285: 4283: 4280: 4278: 4277:Preterm birth 4275: 4273: 4270: 4269: 4267: 4265: 4261: 4251: 4248: 4246: 4243: 4242: 4241: 4238: 4236: 4233: 4231: 4228: 4226: 4223: 4221: 4218: 4216: 4213: 4212: 4211: 4208: 4206: 4203: 4201: 4198: 4196: 4193: 4191: 4188: 4186: 4183: 4182: 4180: 4178: 4174: 4171: 4169: 4163: 4157: 4154: 4152: 4149: 4147: 4144: 4142: 4139: 4137: 4134: 4132: 4129: 4125: 4122: 4120: 4117: 4113: 4112:Clitoral hood 4110: 4109: 4108: 4105: 4104: 4103: 4100: 4099: 4097: 4095: 4089: 4086: 4083: 4080:Reproductive 4076: 4072: 4068: 4060: 4055: 4053: 4048: 4046: 4041: 4040: 4037: 4024: 4020: 4019: 4015: 4014: 4011: 4007: 4000: 3996: 3995: 3991: 3989: 3985: 3984: 3980: 3976: 3974: 3970: 3969: 3965: 3961: 3960: 3957: 3952: 3948: 3941: 3924: 3920: 3916: 3910: 3907: 3894: 3890: 3886: 3882: 3878: 3874: 3870: 3866: 3863:(in French). 3862: 3858: 3851: 3848: 3835: 3831: 3824: 3821: 3808: 3804: 3800: 3793: 3790: 3777: 3773: 3767: 3764: 3751: 3747: 3743: 3736: 3733: 3728: 3722: 3718: 3717: 3709: 3706: 3701: 3697: 3693: 3689: 3685: 3681: 3677: 3673: 3666: 3663: 3658: 3654: 3650: 3646: 3641: 3636: 3632: 3628: 3624: 3617: 3614: 3609: 3605: 3601: 3597: 3593: 3589: 3585: 3581: 3574: 3571: 3566: 3562: 3557: 3552: 3548: 3544: 3540: 3533: 3530: 3525: 3521: 3517: 3513: 3509: 3505: 3501: 3497: 3490: 3487: 3482: 3478: 3474: 3470: 3466: 3462: 3458: 3454: 3447: 3445: 3441: 3436: 3432: 3427: 3422: 3418: 3414: 3410: 3406: 3402: 3395: 3393: 3391: 3389: 3385: 3380: 3376: 3372: 3368: 3364: 3360: 3356: 3352: 3345: 3343: 3341: 3337: 3332: 3328: 3323: 3318: 3314: 3310: 3306: 3302: 3298: 3291: 3288: 3283: 3279: 3273: 3270: 3257: 3253: 3246: 3243: 3238: 3234: 3228: 3224: 3223: 3215: 3213: 3209: 3204: 3200: 3195: 3190: 3186: 3182: 3178: 3174: 3170: 3163: 3160: 3147: 3143: 3136: 3134: 3132: 3128: 3115: 3111: 3105: 3102: 3090: 3086: 3082: 3078: 3074: 3067: 3064: 3052: 3048: 3044: 3040: 3036: 3029: 3026: 3021: 3017: 3013: 3009: 3005: 3001: 2997: 2993: 2986: 2983: 2978: 2974: 2969: 2964: 2960: 2956: 2952: 2945: 2942: 2937: 2933: 2929: 2925: 2921: 2917: 2913: 2909: 2902: 2899: 2886: 2880: 2877: 2872: 2868: 2864: 2860: 2856: 2852: 2848: 2844: 2840: 2836: 2829: 2826: 2821: 2817: 2813: 2809: 2804: 2799: 2795: 2791: 2786: 2781: 2777: 2773: 2769: 2762: 2759: 2746: 2742: 2738: 2733: 2728: 2724: 2720: 2716: 2709: 2706: 2693: 2689: 2685: 2681: 2677: 2670: 2668: 2666: 2664: 2662: 2658: 2645: 2641: 2637: 2633: 2629: 2625: 2621: 2617: 2610: 2607: 2602: 2598: 2593: 2588: 2583: 2578: 2574: 2570: 2566: 2559: 2556: 2551: 2547: 2542: 2537: 2533: 2529: 2525: 2521: 2517: 2510: 2507: 2499: 2495: 2491: 2487: 2483: 2479: 2475: 2468: 2461: 2458: 2453: 2449: 2445: 2441: 2437: 2433: 2429: 2425: 2418: 2415: 2410: 2404: 2400: 2393: 2391: 2389: 2387: 2385: 2381: 2376: 2372: 2367: 2362: 2358: 2354: 2350: 2346: 2342: 2335: 2332: 2319: 2315: 2311: 2305: 2302: 2289: 2285: 2279: 2276: 2271: 2265: 2261: 2256: 2255: 2246: 2243: 2238: 2234: 2230: 2226: 2222: 2218: 2211: 2208: 2203: 2199: 2194: 2189: 2184: 2179: 2175: 2171: 2167: 2160: 2158: 2156: 2154: 2150: 2145: 2141: 2137: 2133: 2129: 2125: 2118: 2116: 2114: 2112: 2110: 2108: 2106: 2104: 2102: 2100: 2098: 2096: 2092: 2087: 2081: 2077: 2076: 2068: 2065: 2052: 2048: 2042: 2038: 2037: 2029: 2026: 2013: 2009: 2003: 1999: 1998: 1990: 1987: 1974: 1970: 1964: 1960: 1959: 1951: 1948: 1935: 1931: 1925: 1921: 1920: 1912: 1910: 1906: 1901: 1897: 1893: 1889: 1885: 1881: 1877: 1873: 1866: 1863: 1850: 1846: 1842: 1838: 1834: 1830: 1826: 1822: 1818: 1814: 1807: 1805: 1803: 1799: 1794: 1790: 1786: 1782: 1778: 1774: 1767: 1764: 1759: 1755: 1751: 1747: 1743: 1739: 1735: 1731: 1724: 1721: 1716: 1712: 1707: 1702: 1698: 1694: 1690: 1686: 1682: 1675: 1673: 1669: 1664: 1660: 1656: 1652: 1648: 1644: 1637: 1635: 1631: 1623: 1619: 1615: 1611: 1607: 1600: 1593: 1591: 1589: 1587: 1585: 1583: 1581: 1579: 1577: 1573: 1568: 1564: 1559: 1554: 1549: 1544: 1540: 1536: 1532: 1525: 1523: 1521: 1519: 1517: 1515: 1513: 1511: 1509: 1507: 1503: 1490: 1486: 1482: 1476: 1474: 1472: 1470: 1468: 1466: 1464: 1460: 1455: 1451: 1447: 1443: 1439: 1435: 1431: 1427: 1420: 1418: 1414: 1407: 1405: 1403: 1399: 1395: 1391: 1387: 1382: 1380: 1376: 1367: 1365: 1363: 1358: 1356: 1352: 1349: 1342:Notable cases 1341: 1339: 1336: 1332: 1328: 1324: 1320: 1317: 1309: 1307: 1306:in neonates. 1305: 1301: 1297: 1290: 1288: 1286: 1282: 1278: 1274: 1273: 1263: 1261: 1259: 1255: 1251: 1244: 1242: 1240: 1236: 1229: 1225: 1218: 1214: 1210: 1202: 1200: 1197: 1195: 1191: 1187: 1183: 1179: 1175: 1171: 1169: 1165: 1161: 1153: 1151: 1147: 1143: 1139: 1135: 1127: 1125: 1123: 1119: 1113: 1111: 1107: 1103: 1095: 1091: 1087: 1080: 1078: 1076: 1072: 1068: 1064: 1060: 1056: 1051: 1043: 1041: 1039: 1035: 1031: 1027: 1023: 1019: 1015: 1007: 999: 996: 994: 991: 990: 989: 986: 983: 982: 976: 974: 971: 970: 969: 966: 965: 960: 957: 955: 952: 950: 947: 944: 943: 942: 939: 938: 933: 930: 928: 925: 923: 920: 918: 915: 913: 912:Cholecystitis 910: 908: 905: 904: 903: 897: 896: 891: 888: 886: 883: 881: 878: 876: 873: 872: 871: 865: 864: 860: 857: 856: 853: 851: 844: 842: 840: 835: 833: 829: 825: 821: 813: 805: 801: 798: 797: 796: 791: 788: 786: 785: 781: 780: 779: 776: 775: 769: 766: 762: 760: 759:liver enzymes 756: 753: 752: 751: 747: 744: 742: 739: 738: 737: 733: 732:Corpus luteum 730: 727: 726: 725: 724: 719: 715: 711: 709: 705: 704: 703: 700: 698: 695: 694: 690: 687: 684: 683: 680: 677: 675: 671: 667: 664:Although the 658: 651: 649: 646: 643: 639: 638:Marlena Fejzo 634: 632: 628: 624: 620: 616: 611: 609: 601: 599: 595: 593: 589: 585: 581: 573: 571: 569: 568:complications 565: 561: 555: 551: 548: 545: 543: 540: 538: 535: 533: 530: 528: 525: 523: 520: 518: 515: 513: 510: 508: 505: 503: 500: 498: 495: 493: 490: 488: 485: 483: 480: 478: 475: 473: 470: 468: 465: 464: 463: 457: 453:Complications 452: 450: 447: 445: 441: 436: 434: 430: 426: 422: 418: 414: 410: 403: 399: 397: 393: 391: 387: 383: 380: 378: 370: 362: 354: 351: 349: 345: 341: 338: 336: 332: 331: 330: 324: 322: 320: 316: 312: 308: 303: 301: 297: 296:Psychotherapy 293: 289: 285: 281: 277: 273: 269: 265: 261: 257: 252: 250: 246: 242: 238: 233: 231: 227: 226: 221: 217: 212: 210: 206: 205:Feeling faint 202: 198: 194: 190: 186: 182: 178: 169: 165: 162: 158: 155: 153: 149: 146: 142: 138: 135: 131: 128: 126: 122: 118: 116: 112: 109: 105: 101: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 60: 58: 54: 51: 47: 44: 42: 38: 33: 27: 19: 5968: 5961: 5821:Vasa praevia 5781: 5755:Locked twins 5671: 5621: 5597: 5465: 5343:Interstitial 5237: 5225: 5213: 4936:Hip fracture 4931:Osteoporosis 4672:Infibulation 4572:Dysmenorrhea 4565:Sanitary pad 4517:Menstruation 4245:Preeclampsia 4240:Hypertension 4214: 4124:Labia majora 4119:Labia minora 4016: 3992: 3977: 3962: 3927:. Retrieved 3918: 3909: 3897:. Retrieved 3864: 3860: 3850: 3838:. Retrieved 3823: 3811:. Retrieved 3802: 3792: 3780:. Retrieved 3766: 3754:. Retrieved 3745: 3735: 3715: 3708: 3675: 3671: 3665: 3630: 3626: 3616: 3583: 3579: 3573: 3546: 3542: 3532: 3499: 3495: 3489: 3459:(2): 87–93. 3456: 3452: 3408: 3404: 3354: 3350: 3304: 3300: 3290: 3281: 3272: 3260:. Retrieved 3245: 3221: 3176: 3172: 3162: 3150:. Retrieved 3118:. Retrieved 3104: 3093:, retrieved 3076: 3066: 3055:, retrieved 3038: 3028: 2995: 2991: 2985: 2958: 2954: 2944: 2911: 2907: 2901: 2889:. Retrieved 2879: 2838: 2828: 2775: 2771: 2761: 2749:. Retrieved 2722: 2718: 2708: 2696:. Retrieved 2679: 2648:. Retrieved 2623: 2619: 2609: 2575:(102): 102. 2572: 2568: 2558: 2523: 2519: 2509: 2477: 2473: 2460: 2427: 2423: 2417: 2398: 2348: 2344: 2334: 2322:. Retrieved 2313: 2304: 2292:. Retrieved 2278: 2253: 2245: 2220: 2216: 2210: 2173: 2169: 2130:(4): 24–28. 2127: 2123: 2074: 2067: 2057:19 September 2055:. Retrieved 2035: 2028: 2018:19 September 2016:. Retrieved 1996: 1989: 1979:19 September 1977:. Retrieved 1957: 1950: 1940:19 September 1938:. Retrieved 1918: 1875: 1865: 1853:. Retrieved 1820: 1816: 1776: 1772: 1766: 1733: 1729: 1723: 1688: 1684: 1646: 1642: 1609: 1605: 1538: 1535:BMC Medicine 1534: 1493:. Retrieved 1484: 1429: 1425: 1383: 1371: 1359: 1353: 1345: 1322: 1318: 1313: 1294: 1275:, a rise in 1270: 1267: 1264:Epidemiology 1248: 1206: 1198: 1194:prednisolone 1172: 1154: 1150:promethazine 1131: 1114: 1090:electrolytes 1084: 1047: 1011: 927:Peptic ulcer 917:Pancreatitis 907:Appendicitis 848: 836: 817: 782: 746:Progesterone 678: 663: 647: 635: 625:(decreasing 612: 605: 596: 584:birth weight 577: 558: 517:malnutrition 507:hypoglycemia 492:coagulopathy 472:hyponatremia 461: 448: 437: 406: 386:ketoacidosis 348:constipation 328: 304: 253: 234: 224: 213: 180: 176: 175: 98:Risk factors 26: 5760:Nuchal cord 5509:Linea nigra 5461:Hepatitis E 5394:proteinuria 5375:Miscarriage 5360:Embryo loss 5338:Heterotopic 5239:WikiProject 4926:Bone health 4862:Lung cancer 4699:Dyspareunia 4642:HPV vaccine 4582:Amenorrhoea 4577:Menorrhagia 4415:Infertility 4364:Stillbirths 4225:Miscarriage 4018:MedlinePlus 3840:24 February 3813:4 September 3782:8 September 2891:18 December 2324:25 February 1481:"Pregnancy" 1362:Amy Schumer 1360:Comedienne 1300:teratogenic 1296:Thalidomide 1250:Acupuncture 1174:Ondansetron 1128:Medications 1059:rehydration 973:Antibiotics 922:Fatty liver 866:Infections 340:Dehydration 335:body weight 311:miscarriage 300:acupressure 288:ondansetron 201:dehydration 197:weight loss 74:dehydration 70:weight loss 18:Hyperemesis 5986:Categories 5770:Postpartum 5665:Antepartum 5380:Stillbirth 5291:puerperium 5289:, and the 5287:childbirth 5164:by country 4968:Depression 4619:infections 4324:Episiotomy 4264:Childbirth 4195:Obstetrics 3756:4 December 3262:27 October 3152:30 January 3120:23 January 3077:StatPearls 3039:StatPearls 2725:(1): S68. 2294:6 December 1495:5 December 1408:References 1335:gravidarum 1329:, and the 1325:, meaning 1304:phocomelia 1239:folic acid 1164:doxylamine 1096:(vitamin B 1055:antiemetic 1044:Management 1030:hematocrit 1022:urinalysis 885:Meningitis 824:Urinalysis 763:Decreased 560:Depression 550:vasospasms 355:, such as 342:, causing 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Index

Hyperemesis
Specialty
Obstetrics
Gastroenterology
Symptoms
Nausea
vomiting
weight loss
dehydration
Risk factors
multiple pregnancy
trophoblastic disorder
Diagnostic method
Differential diagnosis
Urinary tract infection
high thyroid levels
intravenous fluids
Medication
Pyridoxine
metoclopramide
pregnancy complication
nausea
vomiting
weight loss
dehydration
Feeling faint
morning sickness
multiple pregnancy
trophoblastic disorder
Nature

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