46:
38:
363:
1695:
560:
870:
49:
Comprehensive diagram that shows the development of different blood cells from haematopoietic stem cell to mature cells in both myeloid and lymphoid lineages.
1688:
2202:
1815:
1681:
553:
863:
248:, and myelopoiesis in the narrower sense is the regulated formation specifically of myeloid leukocytes (myelocytes), allowing that sense of
546:
856:
607:
100:) is any tissue of, or arising from, bone marrow; in these senses the terms are usually used synonymously, as for example with
163:, are normally born in the bone marrow in adults, myeloid cells in the narrowest sense of the term can be distinguished from
2085:
1893:
891:
326:
280:
101:
2277:
1592:
708:
1552:
2147:
1560:
804:
176:
2249:
2168:
2037:
696:
331:
1486:
1391:
1243:
750:
612:
321:
216:
1293:
732:
713:
41:
Diagram showing the development of different blood cells from haematopoietic stem cell to mature cells
2272:
2244:
1522:
1258:
208:
45:
2032:
2007:
1271:
1040:
725:
479:"Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis"
2178:
1463:
1334:
1096:
1087:
1073:
452:
167:
cells, that is, lymphocytes, which come from common lymphoid progenitor cells that give rise to
256:
and lymphopoiesis (even though all blood cells are normally produced in the marrow in adults).
2042:
1662:
1652:
1364:
1342:
1183:
980:
742:
510:
483:
434:
380:
2119:
2022:
1837:
1629:
1136:
1119:
1000:
950:
945:
691:
590:
500:
492:
424:
416:
372:
200:
184:
79:
2068:
1857:
1789:
1637:
1585:
1537:
1468:
1458:
1055:
883:
786:
646:
574:
120:
2134:
2114:
2063:
1852:
1832:
1827:
1749:
1713:
1514:
1404:
1248:
1226:
1199:
1045:
900:
720:
703:
505:
478:
429:
407:
402:
264:
253:
108:
2266:
2214:
2124:
1769:
1657:
1497:
1322:
1310:
1297:
1281:
1035:
970:
651:
617:
180:
62:
37:
2239:
2173:
2142:
2002:
1867:
1759:
1722:
1705:
1642:
965:
913:
778:
755:
670:
660:
600:
240:
83:
1673:
376:
1916:
1799:
1570:
1419:
1399:
1214:
1209:
1149:
686:
682:
538:
456:
291:
147:), or in a narrower sense also often used, specifically from the lineage of the
132:
124:
57:
31:
30:
This article is about bone marrow cells and tissue. For spinal cord tissue, see
420:
68:
2027:
2017:
1997:
1989:
1951:
1934:
1924:
1862:
1754:
1478:
1347:
1317:
1266:
1171:
879:
638:
629:
595:
570:
336:
164:
160:
148:
116:
96:
2234:
2080:
2012:
1963:
1929:
1794:
1774:
1764:
1441:
1236:
1017:
825:
769:
678:
582:
496:
341:
152:
848:
514:
438:
384:
74:
227:
can often be used to distinguish "erythrocyte-related" from that sense of
2207:
2101:
1980:
1968:
1944:
1939:
1727:
1617:
1580:
1575:
1502:
1374:
955:
940:
918:
833:
260:
156:
144:
140:
136:
128:
2109:
1956:
1647:
1565:
1542:
1446:
1436:
1431:
1369:
1352:
1305:
1010:
960:
935:
656:
196:
17:
527:
Semester 4 medical lectures at
Uppsala University 2008 by Leif Jansson
2197:
2073:
1737:
1602:
1597:
1532:
1527:
1473:
1409:
1357:
1276:
1166:
1154:
1109:
1068:
1063:
1005:
930:
309:
300:
272:
192:
188:
172:
168:
2152:
1612:
1607:
1492:
1219:
1126:
1027:
985:
975:
924:
276:
268:
159:, and their daughter types). Thus, although all blood cells, even
1379:
1114:
990:
908:
305:
1677:
852:
542:
1414:
1231:
995:
477:
Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA (2012).
364:
403:"Hematopoiesis: an evolving paradigm for stem cell biology"
263:
always concern bone marrow cell lineage and are related to
223:
usually refers to nonlymphocytic white blood cells, and
279:, and sometimes even in adults as well, which leads to
244:
has several senses in a way that parallels those of
2227:
2187:
2161:
2133:
2100:
2053:
1988:
1979:
1915:
1906:
1886:
1814:
1736:
1721:
1712:
1628:
1551:
1513:
1390:
1333:
1292:
1257:
1198:
1135:
1095:
1086:
1054:
1026:
899:
890:
824:
817:
795:
777:
768:
741:
669:
637:
628:
581:
267:cells. Myeloid tissue can also be present in the
304:, referring to an insulating layer covering the
396:
394:
361:Kawamoto H, Minato N (2004). "Myeloid cells".
1689:
864:
554:
8:
1985:
1912:
1820:
1742:
1733:
1718:
1696:
1682:
1674:
1092:
896:
871:
857:
849:
821:
774:
634:
561:
547:
539:
504:
428:
183:) is not complete until they migrate to
44:
36:
2203:Megakaryocyte–erythroid progenitor cell
353:
294:", but it is much less commonly used.
7:
102:chronic myeloid/myelogenous leukemia
25:
86:, or resembling bone marrow, and
608:Primitive neuroectodermal tumor
252:to be contradistinguished from
215:, which is associated with the
82:of bone marrow, of bone marrow
290:that means "pertaining to the
1:
1894:Extramedullary hematopoiesis
377:10.1016/j.biocel.2004.01.020
327:Chronic myelogenous leukemia
298:should not be confused with
286:There is one other sense of
281:extramedullary hematopoiesis
453:"Definition of Myelogenous"
115:, or myelogenous cells are
2294:
709:Mesenchymal chondrosarcoma
421:10.1016/j.cell.2008.01.025
29:
2060:Antigen-presenting cells
1848:
1823:
1785:
1745:
401:Orkin SH, Zon LI (2008).
141:common myeloid progenitor
2148:Nucleated red blood cell
1704:Myeloid blood cells and
805:Giant-cell tumor of bone
2250:Hematopoietic stem cell
2169:Leukocyte extravasation
2038:Foreign-body giant cell
697:Extraskeletal chondroma
497:10.1126/science.1216557
332:Hematopoietic stem cell
207:is associated with the
199:challenge. Thus, among
1323:Lymphoid immune system
892:Musculoskeletal system
322:Acute myeloid leukemia
217:adaptive immune system
50:
42:
1311:Myeloid immune system
1097:Cardiovascular system
733:Chondromyxoid fibroma
714:Myxoid chondrosarcoma
48:
40:
27:Tissue of bone marrow
2245:Hematopoietic system
2033:Langhans giant cells
1663:Islets of Langerhans
1523:Genitourinary system
1259:Integumentary system
209:innate immune system
2008:Alveolar macrophage
1553:Reproductive system
1272:Subcutaneous tissue
1041:Cartilaginous joint
726:Osteochondromatosis
491:(6073): 1195–1200.
195:for programming by
187:organs such as the
2179:Intrinsic immunity
2043:Touton giant cells
1335:Respiratory system
1088:Circulatory system
143:, that is, CMP or
119:that arise from a
88:myelogenous tissue
60:sense of the word
51:
43:
2278:Tissues (biology)
2260:
2259:
2223:
2222:
2096:
2095:
2023:Epithelioid cells
1902:
1901:
1882:
1881:
1878:
1877:
1810:
1809:
1671:
1670:
1194:
1193:
1184:Glymphatic system
1082:
1081:
846:
845:
842:
841:
813:
812:
764:
763:
751:Ossifying fibroma
459:. August 28, 2013
211:, in contrast to
16:(Redirected from
2285:
2194:Precursor cells
2120:Promegakaryocyte
1986:
1913:
1838:Promegakaryocyte
1821:
1743:
1734:
1719:
1698:
1691:
1684:
1675:
1630:Endocrine system
1392:Digestive system
1137:Lymphatic system
1120:Lymphatic vessel
1093:
897:
873:
866:
859:
850:
822:
775:
692:Enchondromatosis
635:
591:Multiple myeloma
563:
556:
549:
540:
528:
525:
519:
518:
508:
474:
468:
467:
465:
464:
449:
443:
442:
432:
398:
389:
388:
371:(8): 1374–1379.
358:
21:
2293:
2292:
2288:
2287:
2286:
2284:
2283:
2282:
2263:
2262:
2261:
2256:
2219:
2183:
2162:Immune response
2157:
2135:Red blood cells
2129:
2092:
2069:Langerhans cell
2064:Dendritic cells
2049:
1975:
1898:
1874:
1858:Proerythroblast
1844:
1806:
1790:Monocytopoiesis
1781:
1725:
1708:
1702:
1672:
1667:
1624:
1586:Seminal vesicle
1547:
1509:
1459:Small intestine
1386:
1329:
1288:
1253:
1190:
1131:
1078:
1056:Muscular system
1050:
1022:
901:Skeletal system
886:
877:
847:
838:
809:
791:
787:Chondroblastoma
760:
737:
665:
647:Osteoid osteoma
624:
577:
567:
537:
532:
531:
526:
522:
476:
475:
471:
462:
460:
451:
450:
446:
400:
399:
392:
360:
359:
355:
350:
318:
177:differentiation
175:. Those cells'
121:progenitor cell
35:
28:
23:
22:
15:
12:
11:
5:
2291:
2289:
2281:
2280:
2275:
2265:
2264:
2258:
2257:
2255:
2254:
2253:
2252:
2242:
2237:
2231:
2229:
2225:
2224:
2221:
2220:
2218:
2217:
2212:
2211:
2210:
2205:
2200:
2191:
2189:
2185:
2184:
2182:
2181:
2176:
2171:
2165:
2163:
2159:
2158:
2156:
2155:
2150:
2145:
2139:
2137:
2131:
2130:
2128:
2127:
2122:
2117:
2115:Megakaryoblast
2112:
2106:
2104:
2098:
2097:
2094:
2093:
2091:
2090:
2089:
2088:
2078:
2077:
2076:
2071:
2066:
2057:
2055:
2051:
2050:
2048:
2047:
2046:
2045:
2040:
2035:
2025:
2020:
2015:
2010:
2005:
2000:
1994:
1992:
1983:
1977:
1976:
1974:
1973:
1972:
1971:
1961:
1960:
1959:
1949:
1948:
1947:
1937:
1932:
1927:
1921:
1919:
1910:
1908:Myeloid tissue
1904:
1903:
1900:
1899:
1897:
1896:
1890:
1888:
1884:
1883:
1880:
1879:
1876:
1875:
1873:
1872:
1871:
1870:
1865:
1860:
1853:Erythropoiesis
1849:
1846:
1845:
1843:
1842:
1841:
1840:
1835:
1833:Megakaryoblast
1828:Thrombopoiesis
1824:
1818:
1812:
1811:
1808:
1807:
1805:
1804:
1803:
1802:
1797:
1786:
1783:
1782:
1780:
1779:
1778:
1777:
1772:
1767:
1762:
1757:
1750:Granulopoiesis
1746:
1740:
1731:
1716:
1710:
1709:
1703:
1701:
1700:
1693:
1686:
1678:
1669:
1668:
1666:
1665:
1660:
1655:
1650:
1645:
1640:
1634:
1632:
1626:
1625:
1623:
1622:
1621:
1620:
1615:
1610:
1605:
1600:
1590:
1589:
1588:
1583:
1578:
1573:
1568:
1557:
1555:
1549:
1548:
1546:
1545:
1540:
1535:
1530:
1525:
1519:
1517:
1515:Urinary system
1511:
1510:
1508:
1507:
1506:
1505:
1500:
1495:
1483:
1482:
1481:
1476:
1471:
1466:
1461:
1451:
1450:
1449:
1444:
1439:
1437:Laryngopharynx
1434:
1424:
1423:
1422:
1417:
1412:
1407:
1405:Salivary gland
1396:
1394:
1388:
1387:
1385:
1384:
1383:
1382:
1377:
1372:
1362:
1361:
1360:
1355:
1350:
1339:
1337:
1331:
1330:
1328:
1327:
1326:
1325:
1315:
1314:
1313:
1302:
1300:
1298:immune systems
1294:Haematopoietic
1290:
1289:
1287:
1286:
1285:
1284:
1274:
1269:
1263:
1261:
1255:
1254:
1252:
1251:
1246:
1244:Somatic system
1241:
1240:
1239:
1234:
1227:Sensory system
1224:
1223:
1222:
1217:
1212:
1204:
1202:
1200:Nervous system
1196:
1195:
1192:
1191:
1189:
1188:
1187:
1186:
1179:CNS equivalent
1176:
1175:
1174:
1169:
1159:
1158:
1157:
1152:
1141:
1139:
1133:
1132:
1130:
1129:
1124:
1123:
1122:
1117:
1112:
1101:
1099:
1090:
1084:
1083:
1080:
1079:
1077:
1076:
1071:
1066:
1060:
1058:
1052:
1051:
1049:
1048:
1046:Synovial joint
1043:
1038:
1032:
1030:
1024:
1023:
1021:
1020:
1015:
1014:
1013:
1008:
1003:
998:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
922:
916:
905:
903:
894:
888:
887:
878:
876:
875:
868:
861:
853:
844:
843:
840:
839:
837:
836:
830:
828:
819:
815:
814:
811:
810:
808:
807:
801:
799:
793:
792:
790:
789:
783:
781:
772:
766:
765:
762:
761:
759:
758:
753:
747:
745:
739:
738:
736:
735:
730:
729:
728:
721:Osteochondroma
718:
717:
716:
711:
704:Chondrosarcoma
701:
700:
699:
694:
675:
673:
667:
666:
664:
663:
654:
649:
643:
641:
632:
626:
625:
623:
622:
621:
620:
615:
605:
604:
603:
593:
587:
585:
579:
578:
568:
566:
565:
558:
551:
543:
536:
535:External links
533:
530:
529:
520:
469:
444:
415:(4): 631–644.
390:
352:
351:
349:
346:
345:
344:
339:
334:
329:
324:
317:
314:
254:erythropoiesis
54:Myeloid tissue
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2290:
2279:
2276:
2274:
2271:
2270:
2268:
2251:
2248:
2247:
2246:
2243:
2241:
2238:
2236:
2233:
2232:
2230:
2226:
2216:
2215:Myelomonocyte
2213:
2209:
2206:
2204:
2201:
2199:
2196:
2195:
2193:
2192:
2190:
2186:
2180:
2177:
2175:
2172:
2170:
2167:
2166:
2164:
2160:
2154:
2151:
2149:
2146:
2144:
2141:
2140:
2138:
2136:
2132:
2126:
2125:Megakaryocyte
2123:
2121:
2118:
2116:
2113:
2111:
2108:
2107:
2105:
2103:
2099:
2087:
2084:
2083:
2082:
2079:
2075:
2072:
2070:
2067:
2065:
2062:
2061:
2059:
2058:
2056:
2052:
2044:
2041:
2039:
2036:
2034:
2031:
2030:
2029:
2026:
2024:
2021:
2019:
2016:
2014:
2011:
2009:
2006:
2004:
2003:Kupffer cells
2001:
1999:
1996:
1995:
1993:
1991:
1987:
1984:
1982:
1978:
1970:
1967:
1966:
1965:
1962:
1958:
1955:
1954:
1953:
1950:
1946:
1943:
1942:
1941:
1938:
1936:
1933:
1931:
1928:
1926:
1923:
1922:
1920:
1918:
1914:
1911:
1909:
1905:
1895:
1892:
1891:
1889:
1885:
1869:
1866:
1864:
1861:
1859:
1856:
1855:
1854:
1851:
1850:
1847:
1839:
1836:
1834:
1831:
1830:
1829:
1826:
1825:
1822:
1819:
1817:
1813:
1801:
1798:
1796:
1793:
1792:
1791:
1788:
1787:
1784:
1776:
1773:
1771:
1770:Metamyelocyte
1768:
1766:
1763:
1761:
1758:
1756:
1753:
1752:
1751:
1748:
1747:
1744:
1741:
1739:
1735:
1732:
1729:
1724:
1720:
1717:
1715:
1714:Hematopoiesis
1711:
1707:
1699:
1694:
1692:
1687:
1685:
1680:
1679:
1676:
1664:
1661:
1659:
1656:
1654:
1651:
1649:
1646:
1644:
1641:
1639:
1636:
1635:
1633:
1631:
1627:
1619:
1616:
1614:
1611:
1609:
1606:
1604:
1601:
1599:
1596:
1595:
1594:
1591:
1587:
1584:
1582:
1579:
1577:
1574:
1572:
1569:
1567:
1564:
1563:
1562:
1559:
1558:
1556:
1554:
1550:
1544:
1541:
1539:
1536:
1534:
1531:
1529:
1526:
1524:
1521:
1520:
1518:
1516:
1512:
1504:
1501:
1499:
1498:Biliary tract
1496:
1494:
1491:
1490:
1489:
1488:
1484:
1480:
1477:
1475:
1472:
1470:
1467:
1465:
1462:
1460:
1457:
1456:
1455:
1452:
1448:
1445:
1443:
1440:
1438:
1435:
1433:
1430:
1429:
1428:
1425:
1421:
1418:
1416:
1413:
1411:
1408:
1406:
1403:
1402:
1401:
1398:
1397:
1395:
1393:
1389:
1381:
1378:
1376:
1373:
1371:
1368:
1367:
1366:
1363:
1359:
1356:
1354:
1351:
1349:
1346:
1345:
1344:
1341:
1340:
1338:
1336:
1332:
1324:
1321:
1320:
1319:
1316:
1312:
1309:
1308:
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181:lymphopoiesis
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19:
2174:Phagocytosis
2143:Reticulocyte
1917:Granulocytes
1907:
1868:Reticulocyte
1760:Promyelocyte
1723:Myelopoiesis
1485:
1453:
1426:
1178:
1161:
1144:
1104:
796:
779:Chondroblast
756:Fibrosarcoma
671:Chondroblast
661:osteosarcoma
613:Ewing family
601:Adamantinoma
523:
488:
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472:
461:. Retrieved
447:
412:
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368:
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299:
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287:
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258:
250:myelopoiesis
249:
245:
241:myelopoiesis
239:
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212:
204:
133:erythrocytes
125:granulocytes
112:
106:
95:
91:
87:
84:cell lineage
73:
67:
61:
53:
52:
2273:Blood cells
2028:giant cells
2018:Osteoclasts
1998:Histiocytes
1990:Macrophages
1800:Promonocyte
1653:Parathyroid
1353:Nasopharynx
1215:Spinal cord
1150:Bone marrow
919:Collar bone
687:enchondroma
683:ecchondroma
569:Tumours of
457:MedicineNet
292:spinal cord
221:myelogenous
203:, the term
161:lymphocytes
117:blood cells
58:bone marrow
32:spinal cord
2267:Categories
1952:Eosinophil
1935:Neutrophil
1925:Myeloblast
1863:Normoblast
1755:Myeloblast
1432:Oropharynx
1172:Lymph node
1105:peripheral
951:Metatarsus
946:Metacarpus
925:Thigh bone
921:(clavicle)
639:Osteoblast
630:Metaphysis
463:2015-09-10
348:References
337:Lymphocyte
201:leukocytes
179:(that is,
153:myelocytes
149:myeloblast
2235:Phagocyte
2102:Platelets
2081:Monoblast
2013:Microglia
1981:Monocytes
1964:Mast cell
1930:Band cell
1795:Monoblast
1775:Band cell
1765:Myelocyte
1638:Pituitary
1487:accessory
1442:Esophagus
1162:secondary
1074:Diaphragm
1018:Cartilage
966:Phalanges
826:Notochord
770:Epiphysis
679:Chondroma
596:Epithelia
583:Diaphysis
575:cartilage
342:Myelocyte
261:neoplasms
238:The word
231:and from
225:erythroid
185:lymphatic
157:monocytes
137:platelets
129:monocytes
56:, in the
2208:CFU-GEMM
1969:CFU-Mast
1945:CFU-Baso
1940:Basophil
1728:CFU-GEMM
1618:Placenta
1581:Testicle
1576:Prostate
1503:Pancreas
1464:Appendix
1454:lower GI
1427:upper GI
1375:Bronchus
1318:Lymphoid
1001:Vertebra
956:Ossicles
941:Mandible
834:Chordoma
515:22345399
439:18295580
385:15147715
316:See also
308:of many
259:Myeloid
233:lymphoid
213:lymphoid
165:lymphoid
145:CFU-GEMM
2110:CFU-Meg
1957:CFU-Eos
1887:General
1658:Adrenal
1648:Thyroid
1566:Scrotum
1543:Urethra
1538:Bladder
1447:Stomach
1370:Trachea
1306:Myeloid
1145:primary
1011:Sternum
961:Patella
936:Humerus
927:(femur)
797:Myeloid
743:Fibrous
657:Osteoma
506:3471381
484:Science
430:2628169
310:neurons
296:Myeloid
288:myeloid
277:fetuses
246:myeloid
229:myeloid
205:myeloid
197:antigen
173:T cells
169:B cells
97:-genous
63:myeloid
18:Myeloid
2240:Plasma
2198:CFU-GM
2074:CFU-DL
1738:CFU-GM
1706:plasma
1643:Pineal
1603:Vagina
1598:Uterus
1593:Female
1533:Ureter
1528:Kidney
1474:Rectum
1410:Tongue
1358:Larynx
1277:Breast
1249:Tissue
1167:Spleen
1155:Thymus
1110:Artery
1069:Tendon
1064:Muscle
1028:Joints
1006:Pelvis
981:Tarsus
971:Radius
931:Fibula
914:Carpus
884:organs
513:
503:
437:
427:
383:
301:myelin
273:spleen
193:thymus
189:spleen
92:myelo-
80:tissue
78:), is
69:myelo-
2228:Other
2188:Other
2153:CFU-E
2054:Other
1613:Ovary
1608:Vulva
1571:Penis
1493:Liver
1469:Colon
1420:Tooth
1400:Mouth
1365:Lower
1343:Upper
1220:Nerve
1210:Brain
1127:Heart
986:Tibia
976:Skull
818:Other
306:axons
269:liver
151:(the
139:(the
135:, or
1561:Male
1479:Anus
1380:Lung
1348:Nose
1296:and
1267:Skin
1115:Vein
991:Ulna
909:Bone
882:and
573:and
571:bone
511:PMID
435:PMID
408:Cell
381:PMID
271:and
191:and
171:and
123:for
75:-oid
2086:MPS
1816:MEP
1415:Lip
1237:Eye
1232:Ear
996:Rib
501:PMC
493:doi
489:335
425:PMC
417:doi
413:132
373:doi
275:in
107:In
2269::
509:.
499:.
487:.
481:.
455:.
433:.
423:.
411:.
405:.
393:^
379:.
369:36
367:.
312:.
283:.
235:.
155:,
131:,
127:,
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681:/
659:/
562:e
555:t
548:v
517:.
495::
466:.
441:.
419::
387:.
375::
90:(
66:(
34:.
20:)
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