1537:
1029:
581:
558:
54:
1524:"Lodotra" is the brand name of an oral formulation, which releases prednisone four hours after ingestion. It is indicated for rheumatoid arthritis with morning stiffness. Taken at 10 p.m., it releases the drug at around 2 a.m. The plasmic peak level is reached at 4 a.m., which is considered to be the optimal time for relieving morning stiffness. The drug was approved in the
1433:(ACTH). For this reason, glucocorticoid analogue drugs such as prednisone down-regulate the natural synthesis of glucocorticoids. This mechanism leads to dependence in a short time and can be dangerous if medications are withdrawn too quickly. The body must have time to begin synthesis of CRH and ACTH and for the adrenal glands to begin functioning normally again.
45:
7033:
1453:
The magnitude and speed of dose reduction in corticosteroid withdrawal should be determined on a case-by-case basis, taking into consideration the underlying condition being treated, and individual patient factors such as the likelihood of relapse and the duration of corticosteroid treatment. Gradual
2961:
Buttgereit F, Doering G, Schaeffler A, Witte S, Sierakowski S, Gromnica-Ihle E, et al. (January 2008). "Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial".
1405:
suppression will begin to occur if prednisone is taken for longer than seven days. Eventually, this may cause the body to temporarily lose the ability to manufacture natural corticosteroids (especially cortisol), which results in dependence on prednisone. For this reason, prednisone should not be
1406:
abruptly stopped if taken for more than seven days; instead, the dosage should be gradually reduced. This weaning process may be over a few days if the course of prednisone was short but may take weeks or months if the patient had been on long-term treatment. Abrupt withdrawal may lead to an
2356:
Liu C, Chen Y, Kang Y, Ni Z, Xiu H, Guan J, et al. (October 2011). "Glucocorticoids improve renal responsiveness to atrial natriuretic peptide by up-regulating natriuretic peptide receptor-A expression in the renal inner medullary collecting duct in decompensated heart failure".
1012:
to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large doses of loop diuretics. In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial
3973:
1481:
During corticosteroid withdrawal, the dose may be reduced rapidly down to physiological doses (equivalent to prednisolone 7.5 mg daily) and then reduced more slowly. Assessment of the disease may be needed during withdrawal to ensure that relapse does not occur.
3966:
644:
3959:
1063:
effects such as fluid retention. The mineralocorticoid effects of prednisone are minor, which is why it is not used in the management of adrenal insufficiency, unless a more potent mineralocorticoid is administered concomitantly.
2935:
1637:
1477:
Systemic corticosteroids may be stopped abruptly in those whose disease is unlikely to relapse and who have received treatment for three weeks or less and who are not included in the patient groups described above.
1440:
if used at doses 7–10 mg or higher for several weeks. This is approximately equal to the amount of endogenous cortisol produced by the body every day. As such, the HPA axis starts to become suppressed and
3261:
6411:
4797:
233:
1512:
Prednisone is absorbed in the gastrointestinal tract and has a half-life of 2–3 hours. it has a volume of distribution of 0.4–1 L/kg. The drug is cleared by hepatic metabolism using
2939:
7088:
7000:
3935:
3254:
178:
702:
686:
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
6404:
2321:
Massari F, Mastropasqua F, Iacoviello M, Nuzzolese V, Torres D, Parrinello G (March 2012). "The glucocorticoid in acute decompensated heart failure: Dr Jekyll or Mr Hyde?".
3058:
Wainwright M (1998). "The secret of success: Arthur Nobile's discovery of the steroids prednisone and prednisolone in the 1950s revolutionised the treatment of arthritis".
1445:. If this occurs the patient should be tapered off prednisone slowly to give the adrenal gland enough time to regain its function and endogenous production of steroids.
6368:
4790:
3247:
2688:
1496:
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. Prednisone is a prodrug; it is metabolised in the liver by
6397:
6373:
5888:
4574:
76:
1437:
6665:
1806:
658:
7005:
4783:
3930:
1017:
peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, thereby inducing a potent diuresis.
6123:
2094:
2571:"Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study"
1594:. The first commercially feasible synthesis of prednisone was carried out in 1955 in the laboratories of Schering Corporation, which later became
4518:
3897:
3137:
3107:
3042:
3016:
1910:
The selection and use of essential medicines 2023: web annex A: World Health
Organization model list of essential medicines: 23rd list (2023)
1765:
1620:
Prednisone and prednisolone were introduced in 1955 by
Schering and Upjohn, under the brand names Meticorten and Delta-Cortef, respectively.
824:
2463:
Wolkowitz OM, Lupien SJ, Bigler ED (June 2007). "The "steroid dementia syndrome": a possible model of human glucocorticoid neurotoxicity".
1150:
2728:
1497:
3221:
3199:
6507:
6025:
4567:
2629:
2052:
1889:
678:
5960:
2528:
6280:
5267:
880:
3951:
1418:
335:
218:
108:
2068:
6497:
1941:
1500:
to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to
6675:
6670:
6644:
6632:
6559:
6468:
5881:
5495:
5398:
5352:
5306:
5294:
5204:
5192:
5143:
5092:
4981:
4874:
4749:
3788:
3644:
3600:
3578:
3549:
3537:
3483:
3456:
3347:
3330:
7023:
3085:
7058:
7053:
6995:
6760:
6363:
4560:
3490:
3227:
3205:
2645:
Schakman O, Gilson H, Kalista S, Thissen JP (November 2009). "Mechanisms of muscle atrophy induced by glucocorticoids".
1228:
884:
457:
1110:, but research has found that few of these people were taking medications to protect bones. Prednisone also results in
7073:
6456:
6045:
5636:
5619:
4862:
4714:
4636:
4535:
3914:
1430:
968:
537:
127:
5590:
4847:
3156:
Herzog HL, Nobile A, Tolksdorf S, Charney W, Hershberg EB, Perlman PL (February 1955). "New antiarthritic steroids".
1617:
The enhanced adrenocorticoid activity of these compounds over cortisone and hydrocortisone was demonstrated in mice.
2120:
Riemer AD (April 1958). "Application of the newer corticosteroids to augment diuresis in congestive heart failure".
1454:
withdrawal of systemic corticosteroids should be considered in those whose disease is unlikely to relapse and have:
1410:. For those on chronic therapy, alternate-day dosing may preserve adrenal function and thereby reduce side effects.
6695:
6690:
6492:
6431:
6420:
5965:
5277:
4383:
1553:
1002:
948:
6170:
5756:
4691:
3840:
1905:
1194:
1083:
4908:
1582:
and is also known as δ-cortisone or 1,2-dehydrocortisone or as 17α,21-dihydroxypregna-1,4-diene-3,11,20-trione.
7068:
7063:
6451:
4925:
4857:
4842:
4012:
3354:
1536:
1099:
6685:
4294:
2445:
1028:
406:
6705:
6532:
5624:
5422:
5044:
4954:
7010:
6583:
6527:
6502:
6378:
5871:
5677:
5573:
5561:
5427:
5364:
5068:
5056:
5022:
4949:
4817:
4806:
4523:
4457:
3940:
3902:
3783:
3617:
3432:
813:
164:
5928:
5778:
5653:
5248:
5116:
576:
6680:
6463:
5817:
5790:
5585:
5544:
5522:
5221:
5017:
5005:
4869:
4724:
4328:
4303:
4100:
3763:
3748:
3664:
3467:
3374:
727:
6485:
5810:
5461:
5376:
5104:
4891:
5975:
5970:
5859:
5746:
5689:
5665:
5614:
5507:
5410:
5328:
4937:
4479:
4215:
4111:
4106:
3651:
3561:
2682:
823:
Prednisone was patented in 1954 and approved for medical use in the United States in 1955. It is on the
755:
743:
397:
5761:
4852:
1835:
Buttgereit F, Gibofsky A (June 2013). "Delayed-release prednisone - a new approach to an old therapy".
1079:
5439:
2885:"Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome"
1590:
The first isolation and structure identifications of prednisone and prednisolone were done in 1950 by
831:. In 2022, it was the 30th most commonly prescribed medication in the United States, with more than 18
526:
6815:
6800:
6780:
6710:
6095:
5466:
5340:
5216:
5155:
4624:
4231:
3369:
3359:
3239:
3165:
2750:
Iliopoulou A, Abbas A, Murray R (19 May 2013). "How to manage withdrawal of glucocorticoid therapy".
2225:"Potent diuretic effects of prednisone in heart failure patients with refractory diuretic resistance"
956:
952:
302:
2506:
7083:
6700:
6205:
6090:
5995:
5985:
5517:
5255:
5080:
4070:
3659:
3515:
3444:
1575:
1549:
960:
864:
763:
553:
352:
171:
6320:
6295:
6210:
3115:
6970:
6595:
6512:
6423:
6315:
6215:
6200:
6185:
6157:
6020:
5602:
5138:
4809:
4706:
4666:
4179:
3830:
3804:
3686:
3478:
3417:
3386:
3274:
2987:
2767:
2670:
2544:
2488:
2382:
2303:
2184:"Prednisone adding to usual care treatment for refractory decompensated congestive heart failure"
1860:
1690:
1565:
1426:
1367:
1296:
1282:
1179:
924:
920:
872:
844:
828:
747:
138:
6830:
6165:
4903:
876:
53:
6975:
6275:
6270:
6265:
5901:
Others/atypical (other expanded steroid ring systems, homosteroids, and non-pregnane steroids):
3006:
2619:
2042:
7078:
6900:
6895:
6860:
6855:
6850:
6835:
6571:
6549:
6235:
6110:
6065:
6050:
5945:
4993:
4971:
4641:
3989:
3853:
3313:
3181:
3133:
3067:
3038:
3032:
3012:
2979:
2916:
2816:
2736:
2662:
2625:
2600:
2480:
2374:
2338:
2295:
2254:
2205:
2164:
2137:
2048:
2015:
1885:
1879:
1852:
1761:
1682:
1301:
1164:
1103:
1068:
1060:
1052:
940:
912:
257:
245:
66:
6925:
6290:
6195:
6190:
2702:
506:
6475:
5483:
4920:
4898:
4881:
4450:
4400:
3397:
3173:
2971:
2936:"Delayed-release prednisone (Lodotra™) approved in EU for treatment of rheumatoid arthritis"
2906:
2896:
2806:
2798:
2759:
2654:
2590:
2582:
2536:
2472:
2366:
2330:
2285:
2244:
2236:
2195:
2129:
1913:
1844:
1674:
1378:
1188:
987:
976:
786:
782:
593:
267:
466:
7037:
6578:
6030:
5795:
5087:
5063:
5051:
4629:
4474:
4410:
3753:
3451:
3427:
3412:
3300:
1988:
1595:
1513:
1158:
1040:
817:
446:
285:
275:
6389:
3169:
1816:. St Leonards, Australia: Aspen Pharmacare Australia Pty Ltd. 11 July 2017. pp. 1–2
580:
557:
361:
6870:
6820:
6795:
6785:
6740:
6730:
6715:
6627:
6554:
6543:
6522:
5417:
5388:
5311:
5187:
4976:
4965:
4944:
4831:
4759:
4676:
4614:
4529:
4346:
4251:
4185:
4116:
4035:
3993:
3982:
3908:
3612:
3590:
3337:
3291:
3270:
2911:
2884:
2811:
2786:
2595:
2570:
2405:
2290:
2273:
2249:
2224:
1611:
1571:
1525:
1491:
1407:
1272:
1208:
1203:
995:
991:
723:
2975:
2240:
1467:
recently received repeated courses (particularly if taken for longer than three weeks)
7047:
6755:
6622:
6617:
6220:
6142:
5923:
5822:
5768:
5672:
5609:
5556:
5551:
5529:
5502:
5490:
5393:
5318:
5301:
5289:
5284:
5272:
5182:
5177:
5111:
5029:
4775:
4619:
4604:
4416:
4368:
4299:
4029:
3858:
3708:
3693:
3639:
3595:
3544:
3532:
3527:
3495:
3407:
3325:
2862:
2548:
2133:
1678:
1642:
1591:
1458:
received more than 40 mg prednisone (or equivalent) daily for more than one week
1422:
1402:
1356:
1340:
1238:
1233:
1219:
1009:
888:
798:
569:
100:
3008:
The
Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies
2771:
2674:
2492:
2307:
2155:
Newman DA (February 1959). "Reversal of intractable cardiac edema with prednisone".
1864:
1694:
6960:
6945:
6885:
6810:
6805:
6765:
6735:
6612:
6602:
6339:
6310:
6300:
6285:
6255:
6250:
6240:
6230:
6225:
6175:
6085:
6075:
6070:
6040:
6010:
5913:
5849:
5827:
5706:
5631:
5580:
5534:
5473:
5451:
5347:
5211:
5172:
5162:
5150:
5012:
4587:
4499:
4393:
4353:
4236:
4132:
4085:
3997:
3868:
3825:
3820:
3815:
3768:
3698:
3676:
3671:
3624:
3573:
3500:
3422:
3364:
3282:
3278:
2991:
2386:
1607:
1501:
1414:
1213:
1111:
1107:
1106:
upon dose reduction or cessation. Long-term steroids can also increase the risk of
916:
900:
809:
774:
731:
290:
201:
196:
191:
186:
27:
1963:
1933:
1781:
1727:
86:
3177:
1848:
386:
6965:
6930:
6915:
6875:
6865:
6775:
6770:
6517:
6260:
6060:
6055:
6000:
5980:
5876:
5854:
5844:
5839:
5832:
5805:
5800:
5773:
5741:
5736:
5731:
5568:
5539:
5456:
5446:
5405:
5383:
5371:
5359:
5335:
5128:
5123:
5099:
5075:
4719:
4696:
4671:
4646:
4431:
4319:
4241:
4075:
4045:
3848:
3778:
3773:
3758:
3738:
3733:
3629:
3607:
3568:
3463:
3439:
3320:
2274:"Potent potentiating diuretic effects of prednisone in congestive heart failure"
2009:
2005:
1545:
1287:
1141:
1036:
1014:
928:
892:
94:
2540:
2334:
6955:
6950:
6940:
6935:
6920:
6910:
6890:
6745:
6725:
6607:
6590:
6245:
6180:
6147:
6137:
6015:
5935:
5908:
5903:
5893:
5785:
5726:
5721:
5716:
5696:
5684:
5660:
5648:
5643:
5597:
5478:
5323:
5243:
5238:
5228:
5167:
5039:
4932:
4729:
4661:
4656:
4583:
4504:
4494:
4489:
4426:
4421:
4378:
4373:
4324:
4153:
4126:
4090:
3986:
3883:
3873:
3728:
3723:
3713:
3703:
3681:
3634:
3585:
3556:
3510:
3402:
3093:
2901:
2802:
2476:
1665:
Pickup ME (1979). "Clinical pharmacokinetics of prednisone and prednisolone".
1248:
1056:
1032:
1020:
At high doses it may be used to prevent rejection following organ transplant.
944:
896:
620:
437:
3071:
6825:
6790:
6750:
6720:
6566:
6035:
5940:
5918:
5866:
5711:
5233:
5133:
5034:
5000:
4988:
4915:
4754:
4739:
4609:
4552:
4309:
4284:
4226:
4198:
4169:
4163:
4147:
4137:
4080:
4055:
4050:
3863:
3473:
3308:
2370:
1993:
1599:
1579:
1345:
1291:
1253:
1223:
1172:
1154:
1095:
904:
794:
790:
770:
315:
80:
20:
3185:
2983:
2920:
2820:
2666:
2604:
2484:
2378:
2342:
2299:
2258:
2209:
2168:
2141:
2019:
1856:
36:
6464:
11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)
4870:
11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)
2586:
2182:
Zhang H, Liu C, Ji Z, Liu G, Zhao Q, Ao YG, et al. (September 2008).
1807:"Product Information Panafcort (prednisone) Panafcortelone (prednisolone)"
6880:
6539:
6480:
6305:
6105:
6005:
5950:
5751:
5434:
4961:
4886:
4734:
4651:
4358:
4279:
4268:
4264:
4206:
4065:
4060:
4040:
3878:
3743:
3341:
1686:
1568:
1372:
1350:
1276:
1257:
1183:
1091:
1047:
Short-term side effects, as with all glucocorticoids, include high blood
983:
964:
932:
868:
778:
417:
122:
19:"Deltra" redirects here. For the fishing trawler in service 1951-57, see
2837:
2427:
2011:
LiverTox: Clinical and
Research Information on Drug-Induced Liver Injury
1918:
426:
6845:
6840:
6080:
5990:
4744:
4596:
4274:
4211:
2272:
Liu C, Chen H, Zhou C, Ji Z, Liu G, Gao Y, et al. (October 2006).
2200:
2183:
1442:
1335:
1316:
1310:
1306:
1262:
1072:
1048:
972:
805:
759:
372:
44:
2658:
2406:"Prednisone and other corticosteroids: Balance the risks and benefits"
1001:
Prednisone is often also prescribed as a form of treatment for sudden
4764:
4255:
4221:
2763:
1362:
1267:
908:
848:
751:
735:
517:
320:
2883:
Schijvens AM, Ter Heine R, de Wildt SN, Schreuder MF (March 2019).
1602:
could be microbiologically oxidized to prednisone by the bacterium
486:
6452:
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
6124:
4858:
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
4686:
4484:
2509:. Australian Department of Health & Human Services. April 2016
1535:
1470:
taken a short course within one year of stopping long-term therapy
1168:
1087:
1027:
936:
812:
by the liver before it becomes active. Prednisolone then binds to
643:
634:
497:
294:
5591:
Meprednisone hydrogen succinate (methylprednisone hemisuccinate)
1758:
Goodman & Gilman's the pharmacological basis of therapeutics
860:
856:
852:
739:
477:
6393:
4779:
4556:
3955:
3326:
Desoxycortone (deoxycortone, cortexone, 11-deoxycorticosterone)
3243:
1760:(13 ed.). McGraw-Hill Education. pp. 739, 746, 1237.
251:
117:
2095:"Steroid Treatments Equally Effective Against Sudden Deafness"
1964:"Prednisone Drug Usage Statistics, United States, 2013 - 2022"
5823:
Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate)
2703:"Steroid Drug Withdrawal Symptoms, Treatment & Prognosis"
1055:
or on other medications that increase blood glucose, such as
801:. After prolonged use, prednisone must be stopped gradually.
2569:
Sokhal BS, Hider SL, Paskins Z, Mallen CD, Muller S (2021).
2223:
Liu C, Liu G, Zhou C, Ji Z, Zhen Y, Liu K (September 2007).
1544:
The pharmaceutical industry uses prednisone tablets for the
542:
5828:
Fluocinonide (fluocinolide, fluocinolone acetonide acetate)
975:, and as part of a drug regimen to prevent rejection after
227:
149:
3132:(14th ed.). Merck & Co. Inc. 2006. p. 1327.
2787:"Basic and clinical pharmacology of glucocorticosteroids"
2359:
The
Journal of Pharmacology and Experimental Therapeutics
1516:
enzymes. Metabolites are excreted in the bile and urine.
1436:
Prednisone may start to result in the suppression of the
1008:
Prednisone can be used in the treatment of decompensated
5889:
Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)
240:
1598:, by Arthur Nobile and coworkers. They discovered that
825:
709:
6618:
Prednicarbate (prednisolone ethylcarbonate propionate)
5958:
Non-corticosteroids with some glucocorticoid activity:
5178:
Prednicarbate (prednisolone ethylcarbonate propionate)
2529:"Polymyalgia rheumatica: treatment reviews are needed"
2044:
7021:
3037:. Taylor & Francis. January 2000. pp. 871–.
5045:
Etiprednol dicloacetate (etiprednol dichloroacetate)
2729:"Therapeutic and Adverse Effects of Glucocorticoids"
1413:
Glucocorticoids act to inhibit feedback of both the
785:. Other side effects include weight gain, swelling,
6655:
6555:
Hydrocortamate (hydrocortisone diethylaminoacetate)
6444:
6430:
6329:
6156:
6119:
5722:
Amcinonide (triamcinolone acetate cyclopentanonide)
5545:
Icometasone enbutate (icometasone butyrate acetate)
5222:
Pregnenolone succinate (pregnenolone hemisuccinate)
4977:
Hydrocortamate (hydrocortisone diethylaminoacetate)
4830:
4816:
4705:
4595:
4467:
4442:
4338:
4250:
4196:
4021:
4005:
3839:
3803:
3385:
3299:
3290:
2624:. Lippincott Williams & Wilkins. p. 1062.
1132:
Increased blood sugar for individuals with diabetes
632:
619:
592:
587:
568:
536:
516:
496:
476:
456:
436:
416:
405:
396:
371:
351:
326:
314:
301:
284:
274:
266:
217:
212:
177:
163:
137:
107:
93:
75:
65:
60:
6432:
6129:Tooltip Selective glucocorticoid receptor agonists
5796:Fludroxycortide (flurandrenolone, flurandrenolide)
3754:Fludroxycortide (flurandrenolone, flurandrenolide)
1039:, as may be seen due to long-term prednisone use.
982:Prednisone has also been used in the treatment of
797:and low doses appear to be safe while the user is
6628:Prednisolamate (prednisolone diethylaminoacetate)
5877:Flupamesone (triamcinolone acetonide metembonate)
5188:Prednisolamate (prednisolone diethylaminoacetate)
3034:Index Nominum 2000: International Drug Directory
385:
310:3 to 4 hours in adults. 1 to 2 hours in children
5833:Procinonide (fluocinolone acetonide propionate)
4818:
666:O=C(CO)3(O)CC24CC\C1=C\C(=O)\C=C/1(C)4C(=O)C23C
360:
5319:Ciclometasone (ciclomethasone, cyclomethasone)
3151:
3149:
2878:
2876:
343:17,21-dihydroxypregna-1,4-diene-3,11,20-trione
7089:World Health Organization essential medicines
7001:Mineralocorticoids and antimineralocorticoids
6696:17α-Hydroxyprogesterone (hydroxyprogesterone)
6405:
5562:Locicortolone dicibate (locicortone dicibate)
4840:Cortisol-like and related (16-unsubstituted):
4791:
4568:
3967:
3936:Mineralocorticoids and antimineralocorticoids
3395:Cortisol-like and related (16-unsubstituted):
3255:
2621:Walsh and Hoyt's Clinical Neuro-ophthalmology
8:
2733:U.S. Pharmacist Continuing Education Program
2687:: CS1 maint: DOI inactive as of July 2024 (
1473:other possible causes of adrenal suppression
816:, activating them and triggering changes in
126:
35:
6711:Canrenoate potassium (potassium canrenoate)
6550:Benzodrocortisone (hydrocortisone benzoate)
6476:11-Deoxycortisol (cortodoxone, cortexolone)
5105:Halopredone acetate (halopredone diacetate)
4972:Benzodrocortisone (hydrocortisone benzoate)
4882:11-Deoxycortisol (cortodoxone, cortexolone)
3321:Cortodoxone (cortexolone, 11-deoxycortisol)
2832:
2830:
1464:received more than three weeks of treatment
6441:
6412:
6398:
6390:
4827:
4798:
4784:
4776:
4575:
4561:
4553:
3974:
3960:
3952:
3296:
3262:
3248:
3240:
2323:The American Journal of Emergency Medicine
1722:
1720:
1718:
1716:
1714:
1712:
1710:
1708:
1706:
1704:
579:
556:
445:
52:
43:
6021:Flugestone acetate (flurogestone acetate)
5312:Cortobenzolone (betamethasone salicylate)
3418:Flugestone acetate (flurogestone acetate)
2910:
2900:
2810:
2594:
2289:
2248:
2199:
2075:. U.S. National Library of Medicine. 2009
1917:
1438:hypothalamic–pituitary–adrenal (HPA) axis
1138:Difficulty in maintaining linear thinking
465:
5752:Desonide (hydroxyprednisolone acetonide)
5707:Acrocinonide (triamcinolone acroleinide)
5265:Methasones and related (16-substituted):
3525:Methasones and related (16-substituted):
2869:. NIH U.S. National Library of Medicine.
1751:
1749:
1728:"Prednisone Monograph for Professionals"
1638:"Product monograph brand safety updates"
7028:
6498:16α,18-Dihydroxy-11-deoxycorticosterone
6369:Glucocorticoids and antiglucocorticoids
5717:Amcinafide (triamcinolone acetophenide)
1629:
963:that is common during the treatment of
847:and inflammatory conditions, including
683:
663:
552:
425:
340:
99:
71:Deltasone, Liquid Pred, Orasone, others
6676:7α-Thiomethylspironolactone (SC-26519)
6666:6β-Hydroxy-7α-thiomethylspironolactone
5484:Fluocortin butyl (fluocortin butylate)
2680:
2278:Journal of Cardiovascular Pharmacology
1884:. John Wiley & Sons. p. 485.
1461:been given repeat doses in the evening
843:Prednisone is used for many different
570:
34:
6671:7α-Acetylthio-17α-hydroxyprogesterone
6374:Mineralocorticoid receptor modulators
5791:Fluclorolone acetonide (flucloronide)
5712:Amcinafal (triamcinolone pentanonide)
5112:Isoflupredone (9α-fluoroprednisolone)
3749:Fluclorolone acetonide (flucloronide)
2618:Miller NR, Walsh FB, Hoyt WF (2005).
2400:
2398:
2396:
1912:. Geneva: World Health Organization.
1606:The same process was used to prepare
793:. It is generally considered safe in
525:
505:
85:
7:
1151:Corticosteroid-induced lipodystrophy
1051:levels (especially in patients with
200:
190:
4339:Intestinal anti-inflammatory agents
2099:National Institutes of Health (NIH)
1944:from the original on 30 August 2024
789:, increased risk of infection, and
485:
376:
7006:Glucocorticoid receptor modulators
6437:Tooltip Mineralocorticoid receptor
3931:Glucocorticoid receptor modulators
3222:"Delta-Cortef: FDA-Approved Drugs"
2291:10.1097/01.fjc.0000245242.57088.5b
2229:The Canadian Journal of Cardiology
2157:New York State Journal of Medicine
2122:The American Journal of Cardiology
1492:Glucocorticoid § Pharmacology
1193:Memory and attention dysfunction (
14:
6508:18-Hydroxy-11-deoxycorticosterone
6026:Fluoromedroxyprogesterone acetate
4396:agents, excluding corticosteroids
3112:New Jersey Inventors Hall of Fame
3086:"Inventor Profile: Arthur Nobile"
2575:Rheumatology Advances in Practice
2069:"Antineoplastic Agents, Hormonal"
1837:Expert Opinion on Pharmacotherapy
1782:"Prednisone Use During Pregnancy"
1540:Prednisone 20 mg oral tablet
7031:
6721:Canrenone (canrenoate y-lactone)
6686:7α-Thiospironolactone (SC-24813)
6457:11-Dehydrocorticosterone acetate
5637:Prednylidene diethylaminoacetate
5620:Paramethasone disodium phosphate
5389:Desoximetasone (desoxymethasone)
5244:Butixocort (tixocortol butyrate)
4863:11-Dehydrocorticosterone acetate
3200:"Meticorten: FDA-Approved Drugs"
1679:10.2165/00003088-197904020-00004
1429:gland, decreasing the amount of
1135:Difficulty in regulating emotion
881:granulomatosis with polyangiitis
769:Common side effects may include
604:
6801:Oxprenoate potassium (RU-28318)
6579:Fludrocortisone (fludrocortone)
6091:Segesterone acetate (nestorone)
5704:Cyclic ketals (16,17-cyclized):
5581:Meprednisone (methylprednisone)
5503:Fluprednidene (fluprednylidene)
5052:Fludrocortisone (fludrocortone)
4853:9α-Fluorocortisone (alfluorone)
4823:Tooltip Glucocorticoid receptor
4625:Dronabinol/Tetrahydrocannabinol
3721:Cyclic ketals (16,17-cyclized):
3090:National Inventors Hall of Fame
1878:Fischer J, Ganellin CR (2006).
1419:corticotropin-releasing hormone
1175:, or other psychiatric symptoms
1078:Long-term side effects include
691:Key:XOFYZVNMUHMLCC-ZPOLXVRWSA-N
6481:Cortifen (cortiphen, kortifen)
5961:15β-Hydroxycyproterone acetate
5882:Triamcinolone acetonide esters
5290:Beclometasone (beclomethasone)
4887:Cortifen (cortiphen, kortifen)
4843:3α,5α-Tetrahydrocorticosterone
3789:Triamcinolone acetonide esters
1989:Autoimmune Hepatitis~treatment
610:
598:
1:
6996:Receptor/signaling modulators
6681:7α-Thioprogesterone (SC-8365)
6364:Receptor/signaling modulators
6281:Pregnenolone 16α-carbonitrile
6103:Nonsteroidal glucocorticoids:
5268:16α-Methyl-11-oxoprednisolone
4750:Melanin-concentrating hormone
4443:Antidiarrheal micro-organisms
3774:Formocortal (fluoroformylone)
2976:10.1016/S0140-6736(08)60132-4
2241:10.1016/s0828-282x(07)70840-1
1881:Analogue-based Drug Discovery
6761:Hydroxyprogesterone caproate
5394:Dexamethasone (dexametasone)
5302:Betamethasone (betametasone)
3491:Methylprednisolone aceponate
3228:Food and Drug Administration
3206:Food and Drug Administration
3178:10.1126/science.121.3136.176
3011:. Springer. pp. 1013–.
2450:MedlinePlus Drug Information
2134:10.1016/0002-9149(58)90120-6
1849:10.1517/14656566.2013.782001
1241:– same as avascular necrosis
1229:Steroid-induced osteoporosis
931:, to relieve the effects of
885:adrenocortical insufficiency
6821:Prorenoic acid (prorenoate)
6796:Oxprenoic acid (oxprenoate)
6786:Mexrenoic acid (mexrenoate)
6716:Canrenoic acid (canrenoate)
6337:Antisense oligonucleotides:
6046:Medroxyprogesterone acetate
5757:Desonide disodium phosphate
5557:Locicortolone (locicortone)
4637:Medroxyprogesterone acetate
3005:Elks J (14 November 2014).
2188:International Heart Journal
2041:Wackym PA, Snow JB (2017).
1596:Schering-Plough Corporation
1552:equipment according to the
1431:adrenocorticotropic hormone
1071:or depressive symptoms and
994:. Prednisone is used as an
969:Duchenne muscular dystrophy
746:. It is also used to treat
7105:
6946:Miricorilant (CORT-118335)
6421:Mineralocorticoid receptor
6286:Relacorilant (CORT-125134)
6256:Miricorilant (CORT-118335)
5457:Flumetasone (flumethasone)
5372:Cormetasone (cormethasone)
5278:Alclometasone dipropionate
4285:Camphorated opium tincture
4022:Intestinal anti-infectives
2541:10.3310/nihrevidence_51304
2335:10.1016/j.ajem.2011.01.023
2047:. PMPH USA. p. 1185.
1922:. WHO/MHP/HPS/EML/2023.02.
1554:United States Pharmacopeia
1489:
1315:Weakening and breakage of
1003:sensorineural hearing loss
728:suppress the immune system
726:medication mostly used to
588:Chemical and physical data
25:
18:
6988:
6356:
6216:Exicorilant (CORT-125281)
5447:Doxibetasol (doxybetasol)
5144:Methylprednisolone esters
5129:Mazipredone (depersolone)
4909:Δ-Prednisolone 21-acetate
4513:
3892:
3484:Methylprednisolone esters
2902:10.1007/s00467-018-3929-z
2803:10.2344/0003-3006-60.1.25
2785:Becker DE (Spring 2013).
2477:10.1080/13554790701475468
1906:World Health Organization
1667:Clinical Pharmacokinetics
1195:steroid dementia syndrome
1144:due to increased appetite
1084:steroid dementia syndrome
808:and must be converted to
699:
674:
654:
331:
51:
42:
5685:Ulobetasol (halobetasol)
4926:Chloroprednisone acetate
4848:5α-Dihydrocorticosterone
4218:, known as Pepto-Bismol)
4013:Oral rehydration therapy
3714:Ulobetasol (halobetasol)
3355:Hydrocortisone aceponate
2934:Wan Y (8 January 2009).
2661:(inactive 1 July 2024).
2428:"Prednisone Information"
2073:Medical Subject Headings
1604:Corynebacterium simplex.
814:glucocorticoid receptors
26:Not to be confused with
7011:List of corticosteroids
6706:18,19-Dinorprogesterone
6691:16α-Hydroxyprogesterone
6584:Fludrocortisone acetate
6533:Corticosterone benzoate
6493:11β-Hydroxyprogesterone
6379:List of corticosteroids
6241:Metapristone (RU-42633)
5966:17α-Hydroxyprogesterone
5872:Triamcinolone acetonide
5678:Triamcinolone diacetate
5625:Paramethasone phosphate
5428:Diflucortolone valerate
5423:Diflucortolone pivalate
5069:Fluorometholone acetate
5057:Fludrocortisone acetate
4955:Corticosterone benzoate
4807:Glucocorticoid receptor
4735:Cortisol/Hydrocortisone
4458:Saccharomyces boulardii
3941:List of corticosteroids
3784:Triamcinolone acetonide
3618:Diflucortolone valerate
3433:Fluorometholone acetate
2371:10.1124/jpet.111.184796
835:million prescriptions.
827:. It is available as a
781:, muscle weakness, and
6841:SC-5233 (spirolactone)
6528:Corticosterone acetate
6503:17α-Hydroxyaldosterone
6271:ORG-34517 (SCH-900636)
6171:17α-Methylprogesterone
5818:Fluocinolone acetonide
5574:Meclorisone dibutyrate
5523:Fluticasone propionate
5365:Cloticasone propionate
5093:Fluprednisolone esters
5023:Dichlorisone diacetate
4950:Corticosterone acetate
4725:Agouti-related peptide
3764:Fluocinolone acetonide
3665:Fluticasone propionate
3457:Fluprednisolone esters
3375:Pregnenolone succinate
2727:Bello CS, Garrett SD.
1814:TGA eBusiness Services
1541:
1044:
744:rheumatologic diseases
734:in conditions such as
6560:Hydrocortisone esters
6251:Mifepristone (RU-486)
5976:Chlormadinone acetate
5971:Bromoketoprogesterone
5929:Nicocortonide acetate
5860:Rofleponide palmitate
5779:Drocinonide phosphate
5747:Descinolone acetonide
5742:Deflazacort (azacort)
5690:Ulobetasol propionate
5654:Ticabesone propionate
5615:Paramethasone acetate
5508:Fluprednidene acetate
5411:Diflorasone diacetate
5329:Clobetasol propionate
5249:Butixocort propionate
5117:Isoflupredone acetate
5035:Endrisone (endrysone)
4982:Hydrocortisone esters
4480:Bismuth subsalicylate
4216:bismuth subsalicylate
4112:Succinylsulfathiazole
4107:Phthalylsulfathiazole
3652:Fluprednidene acetate
3562:Clobetasol propionate
3348:Hydrocortisone esters
2797:(1): 25–31, quiz 32.
1934:"The Top 300 of 2022"
1539:
1075:in some individuals.
1031:
756:adrenal insufficiency
6816:Prorenoate potassium
6781:Mexrenoate potassium
6469:Desoxycortone esters
6096:Tetrahydrogestrinone
5936:Nivacortol (nivazol)
5586:Meprednisone acetate
5496:Fluocortolone esters
5467:Flumetasone pivalate
5399:Dexamethasone esters
5341:Clobetasone butyrate
5307:Betamethasone esters
5295:Beclometasone esters
5217:Pregnenolone acetate
5156:Prebediolone acetate
5018:Dichlorisone acetate
5006:Deprodone propionate
4875:Desoxycortone esters
4468:Other antidiarrheals
3645:Fluocortolone esters
3601:Dexamethasone esters
3550:Betamethasone esters
3538:Beclometasone esters
3370:Pregnenolone acetate
3360:Prebediolone acetate
3331:Desoxycortone esters
3118:on 1 September 2011.
3060:Chemistry in Britain
2889:Pediatric Nephrology
2329:(3): 517.e5–517.10.
1098:, diabetes mellitus
957:giant cell arteritis
953:autoimmune hepatitis
7059:Appetite stimulants
7054:Antiasthmatic drugs
6701:18-Deoxyaldosterone
6633:Prednisolone esters
6486:Cortodoxone acetate
6206:Cyproterone acetate
5996:Delmadinone acetate
5986:Cyproterone acetate
5811:Flunisolide acetate
5518:Fluticasone furoate
5462:Flumetasone acetate
5377:Cormetasone acetate
5353:Clocortolone esters
5256:Tixocortol pivalate
5193:Prednisolone esters
5081:Fluperolone acetate
4892:Cortodoxone acetate
4584:Appetite stimulants
4317:does not cross BBB:
3841:Synthesis modifiers
3805:Antiglucocorticoids
3660:Fluticasone furoate
3579:Clocortolone esters
3516:Tixocortol pivalate
3445:Fluperolone acetate
3275:antiglucocorticoids
3170:1955Sci...121..176H
2791:Anesthesia Progress
2587:10.1093/rap/rkab094
1550:dissolution testing
1528:, in January 2009.
961:Herxheimer reaction
865:rheumatic disorders
845:autoimmune diseases
236:(Prescription only)
39:
7074:Mineralocorticoids
6596:Mometasone furoate
6513:19-Norprogesterone
6316:Ulipristal acetate
6186:Asoprisnil ecamate
5666:Timobesone acetate
5603:Mometasone furoate
5139:Methylprednisolone
4938:Cloprednol acetate
4715:ACTH/Corticotropin
4667:Omega-3 fatty acid
4540:Never to phase III
3919:Never to phase III
3831:Ulipristal acetate
3687:Mometasone furoate
3479:Methylprednisolone
2653:(Suppl 1): 36–41.
2201:10.1536/ihj.49.587
1756:Brunton L (2017).
1542:
1427:anterior pituitary
1368:Frequent urination
1297:Avascular necrosis
1080:Cushing's syndrome
1067:It can also cause
1045:
925:nephrotic syndrome
921:multiple sclerosis
873:ulcerative colitis
829:generic medication
748:high blood calcium
16:Steroid medication
7019:
7018:
6984:
6983:
6645:Prednisone esters
6572:Cortisone acetate
6387:
6386:
6352:
6351:
6066:Osaterone acetate
6051:Megestrol acetate
5762:Desonide pivalate
5205:Prednisone esters
4994:Cortisone acetate
4773:
4772:
4765:Orexin/Hypocretin
4642:Megestrol acetate
4550:
4549:
3990:anti-inflammatory
3949:
3948:
3854:Aminoglutethimide
3799:
3798:
3314:Cortisone acetate
3139:978-0-911910-00-1
3044:978-3-88763-075-1
3018:978-1-4757-2085-3
2970:(9608): 205–214.
2659:10.1159/000229762
2006:"Corticosteroids"
1767:978-1-25-958473-2
1408:Addisonian crisis
1302:Hepatic steatosis
1147:Immunosuppression
1061:mineralocorticoid
1053:diabetes mellitus
988:cluster headaches
949:Ménière's disease
941:myasthenia gravis
913:lipid pneumonitis
758:along with other
717:
716:
645:Interactive image
538:CompTox Dashboard
255:
243:
231:
153:
120:
7096:
7036:
7035:
7034:
7027:
6442:
6438:
6434:
6414:
6407:
6400:
6391:
6130:
6126:
5440:Dimesone acetate
4921:Chloroprednisone
4899:21-Deoxycortisol
4828:
4824:
4820:
4800:
4793:
4786:
4777:
4577:
4570:
4563:
4554:
4451:Escherichia coli
4411:Aminosalicylates
4401:Cromoglicic acid
3976:
3969:
3962:
3953:
3398:Chloroprednisone
3297:
3264:
3257:
3250:
3241:
3234:
3233:
3218:
3212:
3211:
3196:
3190:
3189:
3153:
3144:
3143:
3126:
3120:
3119:
3114:. Archived from
3104:
3098:
3097:
3096:on 12 June 2012.
3092:. Archived from
3082:
3076:
3075:
3055:
3049:
3048:
3029:
3023:
3022:
3002:
2996:
2995:
2958:
2952:
2951:
2949:
2947:
2938:. Archived from
2931:
2925:
2924:
2914:
2904:
2880:
2871:
2870:
2859:
2853:
2852:
2850:
2848:
2834:
2825:
2824:
2814:
2782:
2776:
2775:
2764:10.1002/psb.1060
2747:
2741:
2740:
2739:on 11 July 2008.
2735:. Archived from
2724:
2718:
2717:
2715:
2713:
2699:
2693:
2692:
2686:
2678:
2647:Hormone Research
2642:
2636:
2635:
2615:
2609:
2608:
2598:
2566:
2560:
2559:
2557:
2555:
2535:. 21 June 2022.
2525:
2519:
2518:
2516:
2514:
2503:
2497:
2496:
2460:
2454:
2453:
2442:
2436:
2435:
2424:
2418:
2417:
2415:
2413:
2402:
2391:
2390:
2353:
2347:
2346:
2318:
2312:
2311:
2293:
2269:
2263:
2262:
2252:
2220:
2214:
2213:
2203:
2179:
2173:
2172:
2152:
2146:
2145:
2117:
2111:
2110:
2108:
2106:
2091:
2085:
2084:
2082:
2080:
2065:
2059:
2058:
2038:
2032:
2031:
2029:
2027:
2002:
1996:
1985:
1979:
1978:
1976:
1974:
1960:
1954:
1953:
1951:
1949:
1930:
1924:
1923:
1921:
1902:
1896:
1895:
1875:
1869:
1868:
1843:(8): 1097–1106.
1832:
1826:
1825:
1823:
1821:
1811:
1803:
1797:
1796:
1794:
1792:
1778:
1772:
1771:
1753:
1744:
1743:
1741:
1739:
1724:
1699:
1698:
1662:
1656:
1655:
1653:
1651:
1634:
1564:Prednisone is a
1508:Pharmacokinetics
1392:Induced vomiting
1379:intestinal flora
1189:Mental confusion
1129:Steroid myopathy
977:organ transplant
834:
804:Prednisone is a
787:high blood sugar
713:
712:
705:
647:
627:
612:
606:
600:
583:
572:
561:
560:
546:
544:
529:
509:
489:
469:
449:
429:
409:
389:
379:
378:
364:
306:
253:
250:
242:
239:
229:
226:
204:
194:
151:
148:
130:
119:
116:
103:
89:
56:
47:
40:
38:
7104:
7103:
7099:
7098:
7097:
7095:
7094:
7093:
7069:Glucocorticoids
7064:CYP3A4 inducers
7044:
7043:
7042:
7032:
7030:
7022:
7020:
7015:
6980:
6851:SC-11927 (CS-1)
6651:
6436:
6426:
6418:
6388:
6383:
6348:
6343:
6325:
6166:7α-Hydroxy-DHEA
6152:
6128:
6121:
6115:
6031:Fluoxymesterone
5088:Fluprednisolone
5064:Fluorometholone
4822:
4812:
4804:
4774:
4769:
4701:
4591:
4581:
4551:
4546:
4545:
4530:Clinical trials
4509:
4475:Albumin tannate
4463:
4438:
4347:corticosteroids
4334:
4252:Antipropulsives
4246:
4192:
4017:
4001:
3980:
3950:
3945:
3924:
3909:Clinical trials
3888:
3835:
3795:
3452:Fluprednisolone
3428:Fluorometholone
3413:Fludrocortisone
3381:
3292:Glucocorticoids
3286:
3271:Glucocorticoids
3268:
3238:
3237:
3220:
3219:
3215:
3198:
3197:
3193:
3155:
3154:
3147:
3140:
3128:
3127:
3123:
3108:"Arthur Nobile"
3106:
3105:
3101:
3084:
3083:
3079:
3057:
3056:
3052:
3045:
3031:
3030:
3026:
3019:
3004:
3003:
2999:
2960:
2959:
2955:
2945:
2943:
2933:
2932:
2928:
2882:
2881:
2874:
2861:
2860:
2856:
2846:
2844:
2836:
2835:
2828:
2784:
2783:
2779:
2749:
2748:
2744:
2726:
2725:
2721:
2711:
2709:
2701:
2700:
2696:
2679:
2644:
2643:
2639:
2632:
2617:
2616:
2612:
2568:
2567:
2563:
2553:
2551:
2527:
2526:
2522:
2512:
2510:
2505:
2504:
2500:
2462:
2461:
2457:
2444:
2443:
2439:
2426:
2425:
2421:
2411:
2409:
2404:
2403:
2394:
2355:
2354:
2350:
2320:
2319:
2315:
2271:
2270:
2266:
2235:(11): 865–868.
2222:
2221:
2217:
2181:
2180:
2176:
2154:
2153:
2149:
2119:
2118:
2114:
2104:
2102:
2093:
2092:
2088:
2078:
2076:
2067:
2066:
2062:
2055:
2040:
2039:
2035:
2025:
2023:
2014:. 30 May 2014.
2004:
2003:
1999:
1986:
1982:
1972:
1970:
1962:
1961:
1957:
1947:
1945:
1932:
1931:
1927:
1904:
1903:
1899:
1892:
1877:
1876:
1872:
1834:
1833:
1829:
1819:
1817:
1809:
1805:
1804:
1800:
1790:
1788:
1780:
1779:
1775:
1768:
1755:
1754:
1747:
1737:
1735:
1726:
1725:
1702:
1664:
1663:
1659:
1649:
1647:
1636:
1635:
1631:
1626:
1588:
1562:
1534:
1522:
1514:cytochrome P450
1510:
1494:
1488:
1451:
1400:
1395:
1386:Sensitive teeth
1383:Leg pain/cramps
1326:
1321:
1159:central obesity
1120:
1041:Trichrome stain
1026:
990:and for severe
891:due to cancer,
877:Crohn's disease
841:
832:
818:gene expression
708:
706:
703:(what is this?)
700:
695:
692:
687:
682:
681:
670:
667:
662:
661:
650:
625:
615:
609:
603:
564:
540:
532:
512:
492:
472:
452:
432:
412:
392:
375:
367:
347:
344:
339:
338:
304:
276:Bioavailability
268:Pharmacokinetic
262:
208:
166:
159:
140:
133:
31:
24:
17:
12:
11:
5:
7102:
7100:
7092:
7091:
7086:
7081:
7076:
7071:
7066:
7061:
7056:
7046:
7045:
7041:
7040:
7017:
7016:
7014:
7013:
7008:
7003:
6998:
6993:
6989:
6986:
6985:
6982:
6981:
6979:
6978:
6973:
6968:
6963:
6958:
6953:
6948:
6943:
6938:
6933:
6928:
6923:
6918:
6913:
6904:
6903:
6898:
6893:
6888:
6883:
6878:
6873:
6871:Spironolactone
6868:
6863:
6858:
6853:
6848:
6843:
6838:
6833:
6828:
6823:
6818:
6813:
6808:
6803:
6798:
6793:
6788:
6783:
6778:
6773:
6768:
6763:
6758:
6753:
6748:
6743:
6741:Dydrogesterone
6738:
6733:
6731:Dimethisterone
6728:
6723:
6718:
6713:
6708:
6703:
6698:
6693:
6688:
6683:
6678:
6673:
6668:
6659:
6657:
6653:
6652:
6650:
6649:
6648:
6647:
6637:
6636:
6635:
6630:
6625:
6620:
6615:
6610:
6600:
6599:
6598:
6588:
6587:
6586:
6576:
6575:
6574:
6564:
6563:
6562:
6557:
6552:
6544:hydrocortisone
6537:
6536:
6535:
6530:
6523:Corticosterone
6520:
6515:
6510:
6505:
6500:
6495:
6490:
6489:
6488:
6483:
6473:
6472:
6471:
6461:
6460:
6459:
6448:
6446:
6439:
6428:
6427:
6419:
6417:
6416:
6409:
6402:
6394:
6385:
6384:
6382:
6381:
6376:
6371:
6366:
6361:
6357:
6354:
6353:
6350:
6349:
6347:
6346:
6341:
6333:
6331:
6327:
6326:
6324:
6323:
6318:
6313:
6308:
6303:
6298:
6293:
6288:
6283:
6278:
6273:
6268:
6263:
6258:
6253:
6248:
6243:
6238:
6233:
6228:
6223:
6218:
6213:
6208:
6203:
6198:
6193:
6188:
6183:
6178:
6173:
6168:
6162:
6160:
6154:
6153:
6151:
6150:
6145:
6140:
6134:
6132:
6117:
6116:
6114:
6113:
6108:
6099:
6098:
6093:
6088:
6083:
6078:
6073:
6068:
6063:
6058:
6053:
6048:
6043:
6038:
6033:
6028:
6023:
6018:
6013:
6008:
6003:
5998:
5993:
5988:
5983:
5978:
5973:
5968:
5963:
5954:
5953:
5948:
5943:
5938:
5933:
5932:
5931:
5921:
5916:
5911:
5906:
5897:
5896:
5891:
5886:
5885:
5884:
5879:
5869:
5864:
5863:
5862:
5852:
5847:
5842:
5837:
5836:
5835:
5830:
5825:
5815:
5814:
5813:
5803:
5798:
5793:
5788:
5783:
5782:
5781:
5771:
5766:
5765:
5764:
5759:
5749:
5744:
5739:
5734:
5729:
5724:
5719:
5714:
5709:
5700:
5699:
5694:
5693:
5692:
5682:
5681:
5680:
5670:
5669:
5668:
5658:
5657:
5656:
5646:
5641:
5640:
5639:
5629:
5628:
5627:
5622:
5617:
5607:
5606:
5605:
5595:
5594:
5593:
5588:
5578:
5577:
5576:
5566:
5565:
5564:
5554:
5549:
5548:
5547:
5537:
5532:
5527:
5526:
5525:
5520:
5512:
5511:
5510:
5500:
5499:
5498:
5488:
5487:
5486:
5476:
5471:
5470:
5469:
5464:
5454:
5449:
5444:
5443:
5442:
5432:
5431:
5430:
5425:
5418:Diflucortolone
5415:
5414:
5413:
5403:
5402:
5401:
5391:
5386:
5381:
5380:
5379:
5369:
5368:
5367:
5357:
5356:
5355:
5345:
5344:
5343:
5333:
5332:
5331:
5321:
5316:
5315:
5314:
5309:
5299:
5298:
5297:
5287:
5282:
5281:
5280:
5270:
5261:
5260:
5259:
5258:
5253:
5252:
5251:
5236:
5231:
5226:
5225:
5224:
5219:
5209:
5208:
5207:
5197:
5196:
5195:
5190:
5185:
5180:
5175:
5170:
5160:
5159:
5158:
5148:
5147:
5146:
5136:
5131:
5126:
5121:
5120:
5119:
5109:
5108:
5107:
5097:
5096:
5095:
5085:
5084:
5083:
5073:
5072:
5071:
5061:
5060:
5059:
5049:
5048:
5047:
5037:
5032:
5027:
5026:
5025:
5020:
5010:
5009:
5008:
4998:
4997:
4996:
4986:
4985:
4984:
4979:
4974:
4966:hydrocortisone
4959:
4958:
4957:
4952:
4945:Corticosterone
4942:
4941:
4940:
4930:
4929:
4928:
4918:
4913:
4912:
4911:
4904:Δ-Prednisolone
4901:
4896:
4895:
4894:
4889:
4879:
4878:
4877:
4867:
4866:
4865:
4855:
4850:
4845:
4836:
4834:
4825:
4814:
4813:
4805:
4803:
4802:
4795:
4788:
4780:
4771:
4770:
4768:
4767:
4762:
4760:Neuropeptide Y
4757:
4752:
4747:
4742:
4737:
4732:
4727:
4722:
4717:
4711:
4709:
4703:
4702:
4700:
4699:
4694:
4689:
4684:
4679:
4677:Pentoxifylline
4674:
4669:
4664:
4659:
4654:
4649:
4644:
4639:
4634:
4622:
4617:
4615:Cyproheptadine
4612:
4607:
4601:
4599:
4593:
4592:
4582:
4580:
4579:
4572:
4565:
4557:
4548:
4547:
4544:
4543:
4542:
4541:
4538:
4527:
4521:
4515:
4514:
4511:
4510:
4508:
4507:
4502:
4497:
4492:
4487:
4482:
4477:
4471:
4469:
4465:
4464:
4462:
4461:
4454:
4446:
4444:
4440:
4439:
4437:
4436:
4435:
4434:
4429:
4424:
4419:
4406:
4405:
4404:
4403:
4389:
4388:
4387:
4386:
4381:
4376:
4371:
4366:
4361:
4359:Hydrocortisone
4356:
4349:acting locally
4342:
4340:
4336:
4335:
4333:
4332:
4322:
4313:
4312:
4307:
4289:
4288:
4282:
4277:
4272:
4265:Opium tincture
4261:
4259:
4248:
4247:
4245:
4244:
4239:
4234:
4229:
4224:
4219:
4209:
4203:
4201:
4194:
4193:
4191:
4190:
4189:
4188:
4186:Broxyquinoline
4175:
4174:
4173:
4172:
4159:
4158:
4157:
4156:
4143:
4142:
4141:
4140:
4135:
4122:
4121:
4120:
4119:
4117:Sulfaguanidine
4114:
4109:
4096:
4095:
4094:
4093:
4088:
4083:
4078:
4073:
4068:
4063:
4058:
4053:
4048:
4043:
4038:
4036:Amphotericin B
4025:
4023:
4019:
4018:
4016:
4015:
4009:
4007:
4003:
4002:
3994:anti-infective
3983:Antidiarrheals
3981:
3979:
3978:
3971:
3964:
3956:
3947:
3946:
3944:
3943:
3938:
3933:
3928:
3923:
3922:
3921:
3920:
3917:
3906:
3900:
3894:
3893:
3890:
3889:
3887:
3886:
3881:
3876:
3871:
3866:
3861:
3856:
3851:
3845:
3843:
3837:
3836:
3834:
3833:
3828:
3823:
3818:
3809:
3807:
3801:
3800:
3797:
3796:
3794:
3793:
3792:
3791:
3781:
3776:
3771:
3766:
3761:
3756:
3751:
3746:
3741:
3736:
3731:
3726:
3717:
3716:
3711:
3706:
3701:
3696:
3691:
3690:
3689:
3679:
3674:
3669:
3668:
3667:
3662:
3654:
3649:
3648:
3647:
3637:
3632:
3627:
3622:
3621:
3620:
3613:Diflucortolone
3610:
3605:
3604:
3603:
3593:
3591:Desoximetasone
3588:
3583:
3582:
3581:
3571:
3566:
3565:
3564:
3554:
3553:
3552:
3542:
3541:
3540:
3530:
3521:
3520:
3519:
3518:
3508:
3503:
3498:
3493:
3488:
3487:
3486:
3476:
3471:
3461:
3460:
3459:
3449:
3448:
3447:
3437:
3436:
3435:
3425:
3420:
3415:
3410:
3405:
3400:
3391:
3389:
3383:
3382:
3380:
3379:
3378:
3377:
3372:
3362:
3357:
3352:
3351:
3350:
3338:Hydrocortisone
3335:
3334:
3333:
3323:
3318:
3317:
3316:
3305:
3303:
3294:
3288:
3287:
3269:
3267:
3266:
3259:
3252:
3244:
3236:
3235:
3213:
3191:
3145:
3138:
3121:
3099:
3077:
3050:
3043:
3024:
3017:
2997:
2953:
2942:on 9 July 2009
2926:
2895:(3): 389–403.
2872:
2854:
2826:
2777:
2742:
2719:
2694:
2637:
2630:
2610:
2581:(3): rkab094.
2561:
2520:
2498:
2471:(3): 189–200.
2455:
2437:
2419:
2392:
2365:(1): 203–209.
2348:
2313:
2284:(4): 173–176.
2264:
2215:
2194:(5): 587–595.
2174:
2163:(4): 625–633.
2147:
2128:(4): 488–496.
2112:
2086:
2060:
2053:
2033:
1997:
1980:
1955:
1925:
1897:
1890:
1870:
1827:
1798:
1773:
1766:
1745:
1700:
1673:(2): 111–128.
1657:
1628:
1627:
1625:
1622:
1612:hydrocortisone
1587:
1584:
1572:corticosteroid
1561:
1558:
1533:
1530:
1526:European Union
1521:
1518:
1509:
1506:
1487:
1484:
1475:
1474:
1471:
1468:
1465:
1462:
1459:
1450:
1447:
1399:
1396:
1394:
1393:
1390:
1387:
1384:
1381:
1375:
1370:
1365:
1359:
1354:
1348:
1343:
1338:
1332:
1325:
1322:
1320:
1319:
1313:
1304:
1299:
1294:
1285:
1279:
1270:
1265:
1260:
1251:
1245:
1242:
1236:
1231:
1226:
1216:
1211:
1209:Abdominal pain
1206:
1204:Blurred vision
1201:
1200:Muscle atrophy
1198:
1191:
1186:
1176:
1162:
1148:
1145:
1139:
1136:
1133:
1130:
1126:
1119:
1116:
1025:
1022:
996:antitumor drug
992:aphthous ulcer
986:headaches and
840:
837:
762:. It is taken
724:glucocorticoid
715:
714:
697:
696:
694:
693:
690:
688:
685:
677:
676:
675:
672:
671:
669:
668:
665:
657:
656:
655:
652:
651:
649:
648:
640:
638:
630:
629:
623:
617:
616:
613:
607:
601:
596:
590:
589:
585:
584:
574:
566:
565:
563:
562:
549:
547:
534:
533:
531:
530:
522:
520:
514:
513:
511:
510:
502:
500:
494:
493:
491:
490:
482:
480:
474:
473:
471:
470:
462:
460:
454:
453:
451:
450:
442:
440:
434:
433:
431:
430:
422:
420:
414:
413:
411:
410:
402:
400:
394:
393:
391:
390:
382:
380:
369:
368:
366:
365:
357:
355:
349:
348:
346:
345:
342:
334:
333:
332:
329:
328:
324:
323:
318:
312:
311:
308:
299:
298:
288:
282:
281:
278:
272:
271:
264:
263:
261:
260:
248:
237:
223:
221:
215:
214:
210:
209:
207:
206:
183:
181:
175:
174:
169:
167:administration
161:
160:
158:
157:
155:
145:
143:
135:
134:
132:
131:
113:
111:
105:
104:
97:
91:
90:
83:
73:
72:
69:
63:
62:
58:
57:
49:
48:
15:
13:
10:
9:
6:
4:
3:
2:
7101:
7090:
7087:
7085:
7082:
7080:
7077:
7075:
7072:
7070:
7067:
7065:
7062:
7060:
7057:
7055:
7052:
7051:
7049:
7039:
7029:
7025:
7012:
7009:
7007:
7004:
7002:
6999:
6997:
6994:
6991:
6990:
6987:
6977:
6974:
6972:
6969:
6967:
6964:
6962:
6959:
6957:
6954:
6952:
6949:
6947:
6944:
6942:
6939:
6937:
6934:
6932:
6929:
6927:
6924:
6922:
6919:
6917:
6914:
6912:
6909:
6908:Nonsteroidal:
6906:
6905:
6902:
6899:
6897:
6894:
6892:
6889:
6887:
6884:
6882:
6879:
6877:
6874:
6872:
6869:
6867:
6864:
6862:
6859:
6857:
6854:
6852:
6849:
6847:
6844:
6842:
6839:
6837:
6834:
6832:
6829:
6827:
6824:
6822:
6819:
6817:
6814:
6812:
6809:
6807:
6804:
6802:
6799:
6797:
6794:
6792:
6789:
6787:
6784:
6782:
6779:
6777:
6774:
6772:
6769:
6767:
6764:
6762:
6759:
6757:
6756:Guggulsterone
6754:
6752:
6749:
6747:
6744:
6742:
6739:
6737:
6734:
6732:
6729:
6727:
6724:
6722:
6719:
6717:
6714:
6712:
6709:
6707:
6704:
6702:
6699:
6697:
6694:
6692:
6689:
6687:
6684:
6682:
6679:
6677:
6674:
6672:
6669:
6667:
6664:
6661:
6660:
6658:
6654:
6646:
6643:
6642:
6641:
6638:
6634:
6631:
6629:
6626:
6624:
6623:Prednimustine
6621:
6619:
6616:
6614:
6611:
6609:
6606:
6605:
6604:
6601:
6597:
6594:
6593:
6592:
6589:
6585:
6582:
6581:
6580:
6577:
6573:
6570:
6569:
6568:
6565:
6561:
6558:
6556:
6553:
6551:
6548:
6547:
6545:
6541:
6538:
6534:
6531:
6529:
6526:
6525:
6524:
6521:
6519:
6516:
6514:
6511:
6509:
6506:
6504:
6501:
6499:
6496:
6494:
6491:
6487:
6484:
6482:
6479:
6478:
6477:
6474:
6470:
6467:
6466:
6465:
6462:
6458:
6455:
6454:
6453:
6450:
6449:
6447:
6443:
6440:
6435:
6429:
6425:
6422:
6415:
6410:
6408:
6403:
6401:
6396:
6395:
6392:
6380:
6377:
6375:
6372:
6370:
6367:
6365:
6362:
6359:
6358:
6355:
6345:
6344:(ISIS-426115)
6338:
6335:
6334:
6332:
6328:
6322:
6319:
6317:
6314:
6312:
6309:
6307:
6304:
6302:
6299:
6297:
6294:
6292:
6289:
6287:
6284:
6282:
6279:
6277:
6274:
6272:
6269:
6267:
6264:
6262:
6259:
6257:
6254:
6252:
6249:
6247:
6244:
6242:
6239:
6237:
6234:
6232:
6229:
6227:
6224:
6222:
6221:Guggulsterone
6219:
6217:
6214:
6212:
6209:
6207:
6204:
6202:
6199:
6197:
6194:
6192:
6189:
6187:
6184:
6182:
6179:
6177:
6174:
6172:
6169:
6167:
6164:
6163:
6161:
6159:
6155:
6149:
6146:
6144:
6143:Fosdagrocorat
6141:
6139:
6136:
6135:
6133:
6127:
6118:
6112:
6109:
6107:
6104:
6101:
6100:
6097:
6094:
6092:
6089:
6087:
6084:
6082:
6079:
6077:
6074:
6072:
6069:
6067:
6064:
6062:
6059:
6057:
6054:
6052:
6049:
6047:
6044:
6042:
6039:
6037:
6034:
6032:
6029:
6027:
6024:
6022:
6019:
6017:
6014:
6012:
6009:
6007:
6004:
6002:
5999:
5997:
5994:
5992:
5989:
5987:
5984:
5982:
5979:
5977:
5974:
5972:
5969:
5967:
5964:
5962:
5959:
5956:
5955:
5952:
5949:
5947:
5944:
5942:
5939:
5937:
5934:
5930:
5927:
5926:
5925:
5924:Nicocortonide
5922:
5920:
5917:
5915:
5912:
5910:
5907:
5905:
5902:
5899:
5898:
5895:
5892:
5890:
5887:
5883:
5880:
5878:
5875:
5874:
5873:
5870:
5868:
5865:
5861:
5858:
5857:
5856:
5853:
5851:
5848:
5846:
5843:
5841:
5838:
5834:
5831:
5829:
5826:
5824:
5821:
5820:
5819:
5816:
5812:
5809:
5808:
5807:
5804:
5802:
5799:
5797:
5794:
5792:
5789:
5787:
5784:
5780:
5777:
5776:
5775:
5772:
5770:
5769:Dexbudesonide
5767:
5763:
5760:
5758:
5755:
5754:
5753:
5750:
5748:
5745:
5743:
5740:
5738:
5735:
5733:
5730:
5728:
5725:
5723:
5720:
5718:
5715:
5713:
5710:
5708:
5705:
5702:
5701:
5698:
5695:
5691:
5688:
5687:
5686:
5683:
5679:
5676:
5675:
5674:
5673:Triamcinolone
5671:
5667:
5664:
5663:
5662:
5659:
5655:
5652:
5651:
5650:
5647:
5645:
5642:
5638:
5635:
5634:
5633:
5630:
5626:
5623:
5621:
5618:
5616:
5613:
5612:
5611:
5610:Paramethasone
5608:
5604:
5601:
5600:
5599:
5596:
5592:
5589:
5587:
5584:
5583:
5582:
5579:
5575:
5572:
5571:
5570:
5567:
5563:
5560:
5559:
5558:
5555:
5553:
5552:Isoprednidene
5550:
5546:
5543:
5542:
5541:
5538:
5536:
5533:
5531:
5530:Halocortolone
5528:
5524:
5521:
5519:
5516:
5515:
5513:
5509:
5506:
5505:
5504:
5501:
5497:
5494:
5493:
5492:
5491:Fluocortolone
5489:
5485:
5482:
5481:
5480:
5477:
5475:
5472:
5468:
5465:
5463:
5460:
5459:
5458:
5455:
5453:
5450:
5448:
5445:
5441:
5438:
5437:
5436:
5433:
5429:
5426:
5424:
5421:
5420:
5419:
5416:
5412:
5409:
5408:
5407:
5404:
5400:
5397:
5396:
5395:
5392:
5390:
5387:
5385:
5382:
5378:
5375:
5374:
5373:
5370:
5366:
5363:
5362:
5361:
5358:
5354:
5351:
5350:
5349:
5346:
5342:
5339:
5338:
5337:
5334:
5330:
5327:
5326:
5325:
5322:
5320:
5317:
5313:
5310:
5308:
5305:
5304:
5303:
5300:
5296:
5293:
5292:
5291:
5288:
5286:
5285:Amelometasone
5283:
5279:
5276:
5275:
5274:
5273:Alclometasone
5271:
5269:
5266:
5263:
5262:
5257:
5254:
5250:
5247:
5246:
5245:
5242:
5241:
5240:
5237:
5235:
5232:
5230:
5227:
5223:
5220:
5218:
5215:
5214:
5213:
5210:
5206:
5203:
5202:
5201:
5198:
5194:
5191:
5189:
5186:
5184:
5183:Prednimustine
5181:
5179:
5176:
5174:
5171:
5169:
5166:
5165:
5164:
5161:
5157:
5154:
5153:
5152:
5149:
5145:
5142:
5141:
5140:
5137:
5135:
5132:
5130:
5127:
5125:
5122:
5118:
5115:
5114:
5113:
5110:
5106:
5103:
5102:
5101:
5098:
5094:
5091:
5090:
5089:
5086:
5082:
5079:
5078:
5077:
5074:
5070:
5067:
5066:
5065:
5062:
5058:
5055:
5054:
5053:
5050:
5046:
5043:
5042:
5041:
5038:
5036:
5033:
5031:
5030:Difluprednate
5028:
5024:
5021:
5019:
5016:
5015:
5014:
5011:
5007:
5004:
5003:
5002:
4999:
4995:
4992:
4991:
4990:
4987:
4983:
4980:
4978:
4975:
4973:
4970:
4969:
4967:
4963:
4960:
4956:
4953:
4951:
4948:
4947:
4946:
4943:
4939:
4936:
4935:
4934:
4931:
4927:
4924:
4923:
4922:
4919:
4917:
4914:
4910:
4907:
4906:
4905:
4902:
4900:
4897:
4893:
4890:
4888:
4885:
4884:
4883:
4880:
4876:
4873:
4872:
4871:
4868:
4864:
4861:
4860:
4859:
4856:
4854:
4851:
4849:
4846:
4844:
4841:
4838:
4837:
4835:
4833:
4829:
4826:
4821:
4815:
4811:
4808:
4801:
4796:
4794:
4789:
4787:
4782:
4781:
4778:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4736:
4733:
4731:
4728:
4726:
4723:
4721:
4718:
4716:
4713:
4712:
4710:
4708:
4704:
4698:
4695:
4693:
4690:
4688:
4685:
4683:
4680:
4678:
4675:
4673:
4670:
4668:
4665:
4663:
4660:
4658:
4655:
4653:
4650:
4648:
4645:
4643:
4640:
4638:
4635:
4632:
4631:
4626:
4623:
4621:
4620:Dexamethasone
4618:
4616:
4613:
4611:
4608:
4606:
4605:Amitriptyline
4603:
4602:
4600:
4598:
4594:
4589:
4585:
4578:
4573:
4571:
4566:
4564:
4559:
4558:
4555:
4539:
4537:
4534:
4533:
4531:
4528:
4525:
4522:
4520:
4517:
4516:
4512:
4506:
4503:
4501:
4498:
4496:
4493:
4491:
4488:
4486:
4483:
4481:
4478:
4476:
4473:
4472:
4470:
4466:
4460:
4459:
4455:
4453:
4452:
4448:
4447:
4445:
4441:
4433:
4430:
4428:
4425:
4423:
4420:
4418:
4417:Sulfasalazine
4415:
4414:
4413:
4412:
4408:
4407:
4402:
4399:
4398:
4397:
4395:
4391:
4390:
4385:
4384:Beclometasone
4382:
4380:
4377:
4375:
4372:
4370:
4369:Betamethasone
4367:
4365:
4362:
4360:
4357:
4355:
4352:
4351:
4350:
4348:
4344:
4343:
4341:
4337:
4330:
4326:
4323:
4321:
4318:
4315:
4314:
4311:
4308:
4305:
4301:
4300:Diphenoxylate
4298:
4296:
4291:
4290:
4286:
4283:
4281:
4278:
4276:
4273:
4270:
4266:
4263:
4262:
4260:
4257:
4253:
4249:
4243:
4240:
4238:
4235:
4233:
4230:
4228:
4225:
4223:
4220:
4217:
4213:
4210:
4208:
4205:
4204:
4202:
4200:
4195:
4187:
4184:
4183:
4182:
4181:
4177:
4176:
4171:
4168:
4167:
4166:
4165:
4161:
4160:
4155:
4152:
4151:
4150:
4149:
4145:
4144:
4139:
4136:
4134:
4131:
4130:
4129:
4128:
4124:
4123:
4118:
4115:
4113:
4110:
4108:
4105:
4104:
4103:
4102:
4098:
4097:
4092:
4089:
4087:
4084:
4082:
4079:
4077:
4074:
4072:
4069:
4067:
4064:
4062:
4059:
4057:
4054:
4052:
4049:
4047:
4044:
4042:
4039:
4037:
4034:
4033:
4032:
4031:
4027:
4026:
4024:
4020:
4014:
4011:
4010:
4008:
4004:
3999:
3995:
3991:
3988:
3984:
3977:
3972:
3970:
3965:
3963:
3958:
3957:
3954:
3942:
3939:
3937:
3934:
3932:
3929:
3926:
3925:
3918:
3916:
3913:
3912:
3910:
3907:
3904:
3901:
3899:
3896:
3895:
3891:
3885:
3882:
3880:
3877:
3875:
3872:
3870:
3867:
3865:
3862:
3860:
3859:Carbenoxolone
3857:
3855:
3852:
3850:
3847:
3846:
3844:
3842:
3838:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3811:
3810:
3808:
3806:
3802:
3790:
3787:
3786:
3785:
3782:
3780:
3777:
3775:
3772:
3770:
3767:
3765:
3762:
3760:
3757:
3755:
3752:
3750:
3747:
3745:
3742:
3740:
3737:
3735:
3732:
3730:
3727:
3725:
3722:
3719:
3718:
3715:
3712:
3710:
3709:Triamcinolone
3707:
3705:
3702:
3700:
3697:
3695:
3694:Paramethasone
3692:
3688:
3685:
3684:
3683:
3680:
3678:
3675:
3673:
3670:
3666:
3663:
3661:
3658:
3657:
3655:
3653:
3650:
3646:
3643:
3642:
3641:
3640:Fluocortolone
3638:
3636:
3633:
3631:
3628:
3626:
3623:
3619:
3616:
3615:
3614:
3611:
3609:
3606:
3602:
3599:
3598:
3597:
3596:Dexamethasone
3594:
3592:
3589:
3587:
3584:
3580:
3577:
3576:
3575:
3572:
3570:
3567:
3563:
3560:
3559:
3558:
3555:
3551:
3548:
3547:
3546:
3545:Betamethasone
3543:
3539:
3536:
3535:
3534:
3533:Beclometasone
3531:
3529:
3528:Alclometasone
3526:
3523:
3522:
3517:
3514:
3513:
3512:
3509:
3507:
3504:
3502:
3499:
3497:
3496:Prednicarbate
3494:
3492:
3489:
3485:
3482:
3481:
3480:
3477:
3475:
3472:
3469:
3465:
3462:
3458:
3455:
3454:
3453:
3450:
3446:
3443:
3442:
3441:
3438:
3434:
3431:
3430:
3429:
3426:
3424:
3421:
3419:
3416:
3414:
3411:
3409:
3408:Difluprednate
3406:
3404:
3401:
3399:
3396:
3393:
3392:
3390:
3388:
3384:
3376:
3373:
3371:
3368:
3367:
3366:
3363:
3361:
3358:
3356:
3353:
3349:
3346:
3345:
3343:
3339:
3336:
3332:
3329:
3328:
3327:
3324:
3322:
3319:
3315:
3312:
3311:
3310:
3307:
3306:
3304:
3302:
3298:
3295:
3293:
3289:
3284:
3280:
3276:
3272:
3265:
3260:
3258:
3253:
3251:
3246:
3245:
3242:
3231:
3229:
3223:
3217:
3214:
3209:
3207:
3201:
3195:
3192:
3187:
3183:
3179:
3175:
3171:
3167:
3164:(3136): 176.
3163:
3159:
3152:
3150:
3146:
3141:
3135:
3131:
3125:
3122:
3117:
3113:
3109:
3103:
3100:
3095:
3091:
3087:
3081:
3078:
3073:
3069:
3065:
3061:
3054:
3051:
3046:
3040:
3036:
3035:
3028:
3025:
3020:
3014:
3010:
3009:
3001:
2998:
2993:
2989:
2985:
2981:
2977:
2973:
2969:
2965:
2957:
2954:
2941:
2937:
2930:
2927:
2922:
2918:
2913:
2908:
2903:
2898:
2894:
2890:
2886:
2879:
2877:
2873:
2868:
2864:
2858:
2855:
2843:
2839:
2833:
2831:
2827:
2822:
2818:
2813:
2808:
2804:
2800:
2796:
2792:
2788:
2781:
2778:
2773:
2769:
2765:
2761:
2758:(10): 23–29.
2757:
2753:
2746:
2743:
2738:
2734:
2730:
2723:
2720:
2708:
2704:
2698:
2695:
2690:
2684:
2676:
2672:
2668:
2664:
2660:
2656:
2652:
2648:
2641:
2638:
2633:
2631:9780781748117
2627:
2623:
2622:
2614:
2611:
2606:
2602:
2597:
2592:
2588:
2584:
2580:
2576:
2572:
2565:
2562:
2550:
2546:
2542:
2538:
2534:
2533:NIHR Evidence
2530:
2524:
2521:
2508:
2502:
2499:
2494:
2490:
2486:
2482:
2478:
2474:
2470:
2466:
2459:
2456:
2451:
2447:
2441:
2438:
2433:
2429:
2423:
2420:
2408:. Mayo Clinic
2407:
2401:
2399:
2397:
2393:
2388:
2384:
2380:
2376:
2372:
2368:
2364:
2360:
2352:
2349:
2344:
2340:
2336:
2332:
2328:
2324:
2317:
2314:
2309:
2305:
2301:
2297:
2292:
2287:
2283:
2279:
2275:
2268:
2265:
2260:
2256:
2251:
2246:
2242:
2238:
2234:
2230:
2226:
2219:
2216:
2211:
2207:
2202:
2197:
2193:
2189:
2185:
2178:
2175:
2170:
2166:
2162:
2158:
2151:
2148:
2143:
2139:
2135:
2131:
2127:
2123:
2116:
2113:
2101:. 22 May 2015
2100:
2096:
2090:
2087:
2074:
2070:
2064:
2061:
2056:
2054:9781607951773
2050:
2046:
2045:
2037:
2034:
2021:
2017:
2013:
2012:
2007:
2001:
1998:
1995:
1991:
1990:
1984:
1981:
1969:
1965:
1959:
1956:
1943:
1939:
1935:
1929:
1926:
1920:
1915:
1911:
1907:
1901:
1898:
1893:
1891:9783527607495
1887:
1883:
1882:
1874:
1871:
1866:
1862:
1858:
1854:
1850:
1846:
1842:
1838:
1831:
1828:
1815:
1808:
1802:
1799:
1787:
1783:
1777:
1774:
1769:
1763:
1759:
1752:
1750:
1746:
1733:
1729:
1723:
1721:
1719:
1717:
1715:
1713:
1711:
1709:
1707:
1705:
1701:
1696:
1692:
1688:
1684:
1680:
1676:
1672:
1668:
1661:
1658:
1646:. 7 July 2016
1645:
1644:
1643:Health Canada
1639:
1633:
1630:
1623:
1621:
1618:
1615:
1613:
1609:
1605:
1601:
1597:
1593:
1592:Arthur Nobile
1585:
1583:
1581:
1577:
1573:
1570:
1567:
1559:
1557:
1555:
1551:
1547:
1538:
1531:
1529:
1527:
1519:
1517:
1515:
1507:
1505:
1503:
1499:
1493:
1485:
1483:
1479:
1472:
1469:
1466:
1463:
1460:
1457:
1456:
1455:
1448:
1446:
1444:
1439:
1434:
1432:
1428:
1424:
1423:corticotrophs
1420:
1417:, decreasing
1416:
1411:
1409:
1404:
1397:
1391:
1388:
1385:
1382:
1380:
1376:
1374:
1371:
1369:
1366:
1364:
1360:
1358:
1357:Hyperactivity
1355:
1352:
1349:
1347:
1344:
1342:
1339:
1337:
1334:
1333:
1331:
1330:
1323:
1318:
1314:
1312:
1308:
1305:
1303:
1300:
1298:
1295:
1293:
1289:
1286:
1284:
1280:
1278:
1274:
1271:
1269:
1266:
1264:
1261:
1259:
1255:
1252:
1250:
1246:
1243:
1240:
1239:Osteonecrosis
1237:
1235:
1234:Stretch marks
1232:
1230:
1227:
1225:
1221:
1217:
1215:
1212:
1210:
1207:
1205:
1202:
1199:
1196:
1192:
1190:
1187:
1185:
1181:
1177:
1174:
1170:
1166:
1163:
1160:
1156:
1152:
1149:
1146:
1143:
1140:
1137:
1134:
1131:
1128:
1127:
1125:
1124:
1117:
1115:
1113:
1109:
1105:
1101:
1097:
1093:
1090:weight gain,
1089:
1085:
1081:
1076:
1074:
1070:
1065:
1062:
1058:
1054:
1050:
1042:
1038:
1034:
1030:
1023:
1021:
1018:
1016:
1011:
1010:heart failure
1006:
1004:
999:
997:
993:
989:
985:
980:
978:
974:
970:
966:
962:
958:
954:
950:
946:
942:
938:
934:
930:
926:
922:
918:
914:
910:
906:
902:
898:
894:
890:
889:hypercalcemia
886:
882:
878:
874:
870:
866:
862:
858:
854:
850:
846:
838:
836:
830:
826:
821:
819:
815:
811:
807:
802:
800:
799:breastfeeding
796:
792:
788:
784:
780:
776:
772:
767:
765:
761:
757:
753:
749:
745:
741:
737:
733:
730:and decrease
729:
725:
721:
711:
704:
698:
689:
684:
680:
673:
664:
660:
653:
646:
642:
641:
639:
636:
631:
624:
622:
618:
597:
595:
591:
586:
582:
578:
575:
573:
571:ECHA InfoCard
567:
559:
555:
554:DTXSID4021185
551:
550:
548:
539:
535:
528:
524:
523:
521:
519:
515:
508:
504:
503:
501:
499:
495:
488:
484:
483:
481:
479:
475:
468:
464:
463:
461:
459:
455:
448:
444:
443:
441:
439:
435:
428:
424:
423:
421:
419:
415:
408:
404:
403:
401:
399:
395:
388:
384:
383:
381:
374:
370:
363:
359:
358:
356:
354:
350:
341:
337:
330:
325:
322:
319:
317:
313:
309:
307:
300:
296:
292:
289:
287:
283:
279:
277:
273:
269:
265:
259:
249:
247:
238:
235:
225:
224:
222:
220:
216:
211:
203:
198:
193:
188:
185:
184:
182:
180:
176:
173:
170:
168:
162:
156:
147:
146:
144:
142:
136:
129:
124:
115:
114:
112:
110:
106:
102:
98:
96:
92:
88:
84:
82:
78:
74:
70:
68:
64:
61:Clinical data
59:
55:
50:
46:
41:
33:
29:
22:
6961:Nitrendipine
6907:
6886:Trimegestone
6811:Progesterone
6806:Pregnenolone
6766:Medrogestone
6736:Drospirenone
6662:
6639:
6613:Prednazoline
6603:Prednisolone
6336:
6321:Zavacorilant
6311:Toripristone
6301:Telapristone
6296:RTI 3021–022
6291:RTI 3021–012
6231:Lilopristone
6226:Ketoconazole
6211:Dazucorilant
6176:Aglepristone
6102:
6086:Quingestrone
6076:Promegestone
6071:Progesterone
6041:Medrogestone
6011:Etonogestrel
5957:
5914:Domoprednate
5900:
5850:Itrocinonide
5703:
5632:Prednylidene
5535:Halometasone
5514:Fluticasone
5474:Fluocinolone
5452:Fluclorolone
5348:Clocortolone
5264:
5212:Pregnenolone
5199:
5173:Prednazoline
5163:Prednisolone
5151:Prebediolone
5013:Dichlorisone
4839:
4692:Testosterone
4681:
4628:
4500:Racecadotril
4456:
4449:
4409:
4394:antiallergic
4392:
4363:
4354:Prednisolone
4345:
4329:+simethicone
4316:
4292:
4232:Crospovidone
4180:Oxyquinoline
4178:
4162:
4146:
4133:Nifuroxazide
4125:
4101:Sulfonamides
4099:
4086:Streptomycin
4028:
3869:Ketoconazole
3826:Mifepristone
3821:Ketoconazole
3816:Aglepristone
3813:Antagonists:
3812:
3769:Fluocinonide
3720:
3699:Prednylidene
3677:Meprednisone
3672:Halometasone
3656:Fluticasone
3625:Fluclorolone
3574:Clocortolone
3524:
3505:
3501:Prednisolone
3423:Fluocinolone
3394:
3365:Pregnenolone
3225:
3216:
3203:
3194:
3161:
3157:
3129:
3124:
3116:the original
3111:
3102:
3094:the original
3089:
3080:
3063:
3059:
3053:
3033:
3027:
3007:
3000:
2967:
2963:
2956:
2944:. Retrieved
2940:the original
2929:
2892:
2888:
2866:
2863:"Prednisone"
2857:
2845:. Retrieved
2841:
2838:"Prednisone"
2794:
2790:
2780:
2755:
2751:
2745:
2737:the original
2732:
2722:
2710:. Retrieved
2706:
2697:
2683:cite journal
2650:
2646:
2640:
2620:
2613:
2578:
2574:
2564:
2552:. Retrieved
2532:
2523:
2511:. Retrieved
2501:
2468:
2464:
2458:
2449:
2446:"Prednisone"
2440:
2431:
2422:
2410:. Retrieved
2362:
2358:
2351:
2326:
2322:
2316:
2281:
2277:
2267:
2232:
2228:
2218:
2191:
2187:
2177:
2160:
2156:
2150:
2125:
2121:
2115:
2103:. Retrieved
2098:
2089:
2077:. Retrieved
2072:
2063:
2043:
2036:
2024:. Retrieved
2010:
2000:
1987:
1983:
1971:. Retrieved
1967:
1958:
1946:. Retrieved
1937:
1928:
1919:10665/371090
1909:
1900:
1880:
1873:
1840:
1836:
1830:
1818:. Retrieved
1813:
1801:
1789:. Retrieved
1785:
1776:
1757:
1736:. Retrieved
1731:
1670:
1666:
1660:
1648:. Retrieved
1641:
1632:
1619:
1616:
1608:prednisolone
1603:
1589:
1563:
1543:
1523:
1511:
1502:prednisolone
1495:
1486:Pharmacology
1480:
1476:
1452:
1435:
1415:hypothalamus
1412:
1401:
1328:
1327:
1273:Stomach pain
1214:Peptic ulcer
1122:
1121:
1112:leukocytosis
1108:osteoporosis
1077:
1066:
1046:
1024:Side effects
1019:
1007:
1000:
981:
917:pericarditis
901:tuberculosis
842:
839:Medical uses
822:
810:prednisolone
803:
768:
732:inflammation
719:
718:
707:
701:
303:Elimination
291:prednisolone
219:Legal status
213:Legal status
109:License data
32:
28:Prednisolone
6971:PF-03882845
6966:Ocedurenone
6931:Esaxerenone
6916:Apararenone
6876:Spiroxasone
6866:Spirorenone
6776:Metribolone
6771:Mespirenone
6656:Antagonists
6518:Aldosterone
6261:Onapristone
6201:CORT-108297
6158:Antagonists
6061:Norgestomet
6056:Metribolone
6001:Desogestrel
5981:Cyproterone
5855:Rofleponide
5845:Halcinonide
5840:Formocortal
5806:Flunisolide
5801:Flumoxonide
5774:Drocinonide
5737:Cicortonide
5732:Ciclesonide
5569:Meclorisone
5540:Icometasone
5406:Diflorasone
5384:Descinolone
5360:Cloticasone
5336:Clobetasone
5124:Loteprednol
5100:Halopredone
5076:Fluperolone
4720:Adiponectin
4697:Thalidomide
4672:Oxandrolone
4647:Mirtazapine
4526:from market
4432:Balsalazide
4320:Eluxadoline
4287:(paregoric)
4242:Diosmectite
4237:Attapulgite
4214:(including
4197:Intestinal
4076:Polymyxin B
4071:Paromomycin
4046:Fidaxomicin
4030:Antibiotics
4006:Rehydration
3905:from market
3849:Acetoxolone
3779:Halcinonide
3759:Flunisolide
3739:Deflazacort
3734:Ciclesonide
3630:Flumetasone
3608:Diflorasone
3569:Clobetasone
3468:+tobramycin
3464:Loteprednol
3440:Fluperolone
3130:Merck Index
2946:22 November
2867:MedlinePlus
2707:MedicineNet
2079:11 November
2022:. NBK548400
1791:24 December
1738:24 December
1546:calibration
1421:(CRH), and
1336:Nervousness
1288:Mouth sores
1268:Black stool
1142:Weight gain
1037:fatty liver
1015:natriuretic
929:sarcoidosis
893:thyroiditis
871:disorders,
628: g·mol
577:100.000.147
327:Identifiers
95:MedlinePlus
67:Trade names
7084:Triketones
7048:Categories
6956:Nimodipine
6951:Nifedipine
6941:Finerenone
6936:Felodipine
6921:Benidipine
6911:Amlodipine
6891:Vamorolone
6831:RO-14-9012
6746:Eplerenone
6726:Dicirenone
6663:Steroidal:
6640:Prednisone
6608:Prednazate
6591:Mometasone
6424:modulators
6340:IONIS-GCCR
6246:Miconazole
6181:Asoprisnil
6148:Mapracorat
6138:Dagrocorat
6016:Flugestone
5909:Cortivazol
5904:Cortisuzol
5894:Triclonide
5786:Fluazacort
5727:Budesonide
5697:Vamorolone
5661:Timobesone
5649:Ticabesone
5644:Rimexolone
5598:Mometasone
5479:Fluocortin
5324:Clobetasol
5239:Tixocortol
5229:Resocortol
5200:Prednisone
5168:Prednazate
5040:Etiprednol
4933:Cloprednol
4810:modulators
4730:Anandamide
4707:Endogenous
4682:Prednisone
4662:Olanzapine
4657:Nandrolone
4505:Kaopectate
4495:Octreotide
4490:Crofelemer
4427:Olsalazine
4422:Mesalazine
4379:Budesonide
4374:Tixocortol
4364:Prednisone
4325:Loperamide
4199:adsorbents
4154:Miconazole
4127:Nitrofuran
4091:Vancomycin
3987:intestinal
3884:Trilostane
3874:Metyrapone
3729:Budesonide
3724:Amcinonide
3704:Rimexolone
3682:Mometasone
3635:Fluocortin
3586:Cortivazol
3557:Clobetasol
3511:Tixocortol
3506:Prednisone
3403:Cloprednol
2847:29 January
2752:Prescriber
2507:"Steroids"
1624:References
1576:derivative
1490:See also:
1449:Withdrawal
1398:Dependency
1361:Increased
1249:joint pain
1165:Depression
1104:depression
1069:depression
1057:tacrolimus
1033:Micrograph
947:exposure,
945:poison oak
897:laryngitis
720:Prednisone
633:3D model (
621:Molar mass
507:CHEBI:8382
467:VB0R961HZT
438:ChemSpider
398:IUPHAR/BPS
353:CAS Number
336:IUPAC name
286:Metabolism
128:Prednisone
37:Prednisone
6976:SM-368229
6826:Prorenone
6791:Mexrenone
6751:Gestodene
6567:Cortisone
6276:ORG-34850
6266:ORG-34116
6036:Gestodene
5941:Oxisopred
5919:Naflocort
5867:Tralonide
5234:Tipredane
5134:Medrysone
5001:Deprodone
4989:Cortisone
4916:Amebucort
4755:Melatonin
4740:Cortisone
4610:Clonidine
4597:Exogenous
4536:Phase III
4524:Withdrawn
4485:Ceratonia
4310:Difenoxin
4304:+atropine
4170:Acetarsol
4164:Arsenical
4148:Imidazole
4138:Nifurzide
4081:Rifaximin
4056:Natamycin
4051:Kanamycin
3915:Phase III
3903:Withdrawn
3864:Enoxolone
3474:Medrysone
3387:Synthetic
3309:Cortisone
3072:106716069
3066:(1): 46.
2549:251774691
2465:Neurocase
2432:Drugs.com
1994:eMedicine
1973:30 August
1948:30 August
1786:Drugs.com
1732:Drugs.com
1600:cortisone
1580:cortisone
1566:synthetic
1560:Chemistry
1346:Skin rash
1292:dry mouth
1254:Cataracts
1224:shoulders
1173:psychosis
1155:moon face
1096:cataracts
1005:(SSNHL).
899:, severe
795:pregnancy
791:psychosis
775:bone loss
771:cataracts
527:ChEMBL635
316:Excretion
305:half-life
165:Routes of
139:Pregnancy
87:Monograph
81:Drugs.com
21:FV Deltra
7079:Prodrugs
7038:Medicine
6992:See also
6901:ZK-97894
6896:ZK-91587
6881:Tibolone
6861:SC-27169
6856:SC-19886
6836:RU-26752
6540:Cortisol
6445:Agonists
6360:See also
6306:Tibolone
6236:LLY-2707
6111:GSK-9027
6106:AZD-5423
6006:DU-41165
5951:RU-28362
5946:RU-26988
5435:Dimesone
4962:Cortisol
4832:Agonists
4652:Nabilone
4630:Cannabis
4293:crosses
4280:Morphine
4269:laudanum
4207:Charcoal
4066:Nystatin
4061:Neomycin
4041:Colistin
3996:agents (
3927:See also
3879:Mitotane
3744:Desonide
3342:cortisol
3186:13225767
2984:18207016
2921:29549463
2842:DrugBank
2821:23506281
2772:72082017
2675:21997662
2667:19940494
2605:34988356
2554:5 August
2493:39340010
2485:17786779
2379:21737535
2343:21406321
2308:45800521
2300:17086096
2259:17876376
2210:18971570
2169:13632954
2142:13520608
2026:19 March
2020:31643719
1968:ClinCalc
1942:Archived
1938:ClinCalc
1908:(2023).
1865:22720230
1857:23594208
1695:12218704
1569:pregnane
1532:Industry
1498:11-β-HSD
1389:Headache
1377:Reduced
1373:Diarrhea
1351:Appetite
1283:swelling
1277:bloating
1258:glaucoma
1244:Insomnia
1218:Painful
1184:weakness
1178:Unusual
1092:glaucoma
984:migraine
965:syphilis
933:shingles
869:allergic
779:bruising
764:by mouth
760:steroids
710:(verify)
418:DrugBank
179:ATC code
172:By mouth
141:category
123:DailyMed
6926:BR-4628
6846:SC-8109
6196:C113176
6191:C108297
6081:RU-2309
5991:Danazol
4745:Ghrelin
4275:Codeine
4256:opioids
4212:Bismuth
3301:Natural
3166:Bibcode
3158:Science
2992:6197980
2912:6349812
2812:3601727
2712:14 June
2596:8712242
2513:14 June
2412:7 April
2387:1892149
2250:2651362
1820:30 June
1650:3 April
1586:History
1556:(USP).
1520:Lodotra
1443:atrophy
1425:in the
1403:Adrenal
1329:Source:
1317:tendons
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