Knowledge (XXG)

Rosacea

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modalities of rosacea treatment are topical and oral antibiotic agents. Laser therapy has also been classified as a form of treatment. While medications often produce a temporary remission of redness within a few weeks, the redness typically returns shortly after treatment is suspended. Long-term treatment, usually 1–2 years, may result in permanent control of the condition for some patients. Lifelong treatment is often necessary, although some cases resolve after a while and go into a permanent remission. Other cases, if left untreated, worsen over time. Some people have also reported better results after changing diet. This is not confirmed by medical studies, even though some studies relate the histamine production to outbreak of rosacea.
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associated with rosacea symptoms. The benefits of systemic doxycycline include its effectiveness in reducing inflammatory lesions, improving erythema, and controlling symptoms related to ocular involvement in rosacea patients; it is also well-tolerated at lower doses compared to traditional higher-dose regimens used for other indications. However, potential cons include gastrointestinal side effects such as nausea or abdominal pain, photosensitivity reactions that require sun protection measures during treatment, and rare instances of antibiotic-associated diarrhea or bacterial resistance development with long-term use.
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inflammatory markers in clinical studies; overall, it decreases Demodex mite density and improves the symptoms of inflammation associated with rosacea; however, some patients may experience transient burning or itching upon application. Topical ivermectin offers a targeted approach for managing rosacea by addressing the role of Demodex mites in the disease process. A review found that ivermectin was more effective than alternatives for treatment of papulopustular acne rosacea. An ivermectin cream has been approved by the
831:, or waterproof makeup to the affected area as these products can compromise the skin barrier protection and be difficult to remove. Using soap-free cleansers and non-oily moisturizers are preferred if used on the affected area. Many skin care products have been specifically formulated for those with sensitive skin or for those with conditions such as rosacea. Ocular rosacea may be treated with daily gentle eyelid washing using warm water, and artificial tears to lubricate the eye. 894:
associated with rosacea by inhibiting both microbial growth and pro-inflammatory mediators generated by neutrophils. Benefits of topical metronidazole include its effectiveness in reducing symptoms, extensive clinical experience supporting its use, and generally good tolerability with minimal systemic side effects; still, some patients may experience mild local irritation upon initial use, and it may have limited impact on persistent facial redness (erythema).
393: 827:(with a sun factor protection (SPF) of 30 or greater) and avoid cosmetics. If using cosmetics or makeup is desired, then oil free foundation and concealer should be used. Skin astringents, products that can dry the skin and impair the skin barrier, including products with alcohol, menthol, peppermint, camphor, or eucalyptus oil, should generally be avoided. People should avoid using exfoliating skin scrubs, cosmetics or soaps containing 703: 890:
formulation and is applied to the affected areas once daily. Minocycline belongs to the tetracycline family of antibiotics and exhibits antimicrobial properties and anti-inflammatory activity, similar to other members of this class, such as doxycycline. Topical minocycline reduces inflammatory lesions associated with rosacea; however, rare adverse events such as folliculitis have been reported.
669:(SIBO) was demonstrated to have greater prevalence in rosacea patients and treating it with locally acting antibiotics led to rosacea lesion improvement in two studies. Conversely in rosacea patients who were SIBO negative, antibiotic therapy had no effect. The effectiveness of treating SIBO in rosacea patients may suggest that gut bacteria play a role in the pathogenesis of rosacea lesions. 492: 695: 1034: 62: 1682:
Kenshi Yamasaki, Anna Di Nardo, Antonella Bardan, Masamoto Murakami, Takaaki Ohtake, Alvin Coda, Robert A Dorschner, Chrystelle Bonnart, Pascal Descargues, Alain Hovnanian, Vera B Morhenn, Richard L Gallo (August 2007). "Increased serine protease activity and cathelicidin promotes skin inflammation
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Certain behavioral changes may improve the symptoms of rosacea or help to prevent exacerbations. Keeping a symptoms diary to document potential symptom triggers and avoiding those triggers is recommended. Common exacerbating triggers include ultraviolet light and irritant cosmetics, therefore it is
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Most people with rosacea have only mild redness and are never formally diagnosed or treated. No test for rosacea is known. In many cases, simple visual inspection by a trained health-care professional is sufficient for diagnosis. In other cases, particularly when pimples or redness on less-common
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Topical azelaic acid is available in gel or cream formulations; it exerts its effects by reducing inflammation through its activity on the cathelicidin pathway, which is upregulated in rosacea-affected skin; it also reduces inflammatory lesions and improves overall symptoms of rosacea; it has been
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Systemic doxycycline modified-release capsules are commonly used for the treatment of rosacea. The capsules are taken orally once daily, usually in a low dose, to achieve anti-inflammatory effects. Doxycycline acts by inhibiting inflammation and reducing the production of reactive oxygen species
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Topical ivermectin is a treatment option for rosacea that targets Demodex mites, which are associated with inflammation in the skin of patients with rosacea; the cream is applied once daily to clean, dry skin. Topical ivermectin has been shown to reduce Demodex mite density and improve cutaneous
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Topical minocycline applied as a foam is a newer treatment option for rosacea that the FDA has approved. Minocycline shows a targeted approach for managing inflammatory lesions of rosacea while minimizing systemic side effects commonly associated with oral antibiotic use. It is available in foam
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Topical metronidazole is a commonly used treatment for rosacea; it is available in various formulations such as creams, gels, or lotions and applied to clean, dry skin once or twice daily. Topical metronidazole has been shown to effectively reduce inflammatory lesions and perilesional erythema
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Therapy for the treatment of rosacea is not curative, and is best measured in terms of reduction in the amount of facial redness and inflammatory lesions, a decrease in the number, duration, and intensity of flares, and concomitant symptoms of itching, burning, and tenderness. The two primary
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standard therapy. Quassia amara extract at 4% demonstrated to have clinical efficacy for rosacea. When compared to metronidazole 0.75% as usual care in a randomized, double-blinded clinical trial, Quassia amara extract at 4% demonstrated earlier onset of action, including improvement in
511:, stress, anxiety, cold wind, and moving to a warm or hot environment from a cold one, such as heated shops and offices during the winter, can each cause the face to become flushed. Certain foods and drinks can also trigger flushing, such as alcohol, foods and beverages containing 735:, an enlargement of the nose. Signs include thickening skin, irregular surface nodularities, and enlargement. Phymatous rosacea can also affect the chin (gnathophyma), forehead (metophyma), cheeks, eyelids (blepharophyma), and ears (otophyma). Telangiectasias may be present. 649:
stimulated an immune system response in 79 percent of 22 patients with subtype 2 (papulopustular) rosacea, compared with only 29% of 17 subjects without the disorder. They concluded, "The immune response results in inflammation, as evident in the papules (bumps) and
725:) and possibly intense burning, stinging, and itching are common. People with this type often have sensitive skin. Skin can also become very dry and flaky. In addition to the face, signs can also appear on the ears, neck, chest, upper back, and scalp. 992:
Encapsulated benzoyl peroxide (E-BPO) cream, a newly FDA-approved topical agent for inflammatory lesions of rosacea, utilizes porous silica microcapsule technology to slow the absorption of benzoyl peroxide and diminish potential irritation.
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The highly visible nature of rosacea symptoms are often psychologically challenging for those affected. People with rosacea can experience issues with self-esteem, socializing, and changes to their thoughts, feelings, and coping mechanisms.
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by mouth. Isotretinoin and tetracycline antibiotics, which may be used in more severe cases of inflammatory rosacea, are absolutely contraindicated in women who are pregnant, may become pregnant or lactating as they are highly
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The cause of rosacea is unknown. Risk factors are believed to include a family history of the condition. Factors that may potentially worsen the condition include heat, exercise, sunlight, cold, spicy food, alcohol,
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eye drops have been shown to reduce symptoms in those with ocular rosacea. Cyclosporin should not be used in those with an active ocular infection. Other options include topical metronidazole cream or topical
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The exact cause of rosacea is unknown. Triggers that cause episodes of flushing and blushing play a part in its development. Exposure to temperature extremes, strenuous exercise, heat from sunlight, severe
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showing rosacea as enlarged, dilated capillaries and venules located in the upper dermis, angulated telangiectasias, perivascular and perifollicular lymphocytic infiltration, and superficial dermal edema.
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Rosacea affects between 1% and 10% of people. Those affected are most often 30 to 50 years old and female. Fair-skinned people seem to be more commonly affected. The condition was described in
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Papulopustular rosacea presents with some permanent redness with red bumps (papules); some pus-filled pustules can last 1–4 days or longer. This subtype is often confused with acne.
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such as brimonidine which has vasoconstrictor activity and achieves maximal symptom improvement 3-6 hours after application, other topicals used for flushing or erythema include
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applied to the eyelids, or oral doxycycline in more severe cases of ocular rosacea. If papules and pustules persist, then sometimes isotretinoin can be prescribed.
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Metronidazole is thought to act through anti-inflammatory mechanisms, while azelaic acid is thought to decrease cathelicidin production. Oral antibiotics of the
5237: 3614: 2683:"The efficacy, safety, and tolerability of ivermectin compared with current topical treatments for the inflammatory lesions of rosacea: a network meta-analysis" 886:
are also commonly used and thought to reduce papulopustular lesions through anti-inflammatory actions rather than through their antibacterial capabilities.
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well-studied and shown to be effective in clinical trials; still, some patients may experience mild local irritation during the first few weeks of use.
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parts of the face is present, a trial of common treatments is useful for confirming a suspected diagnosis. The disorder can be confused or co-exist with
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can also be used for flushing symptoms. The flushing and blushing that typically accompany rosacea may also be treated with the topical application of
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Ferrari A, Diehl C (January 2012). "Evaluation of the Efficacy and Tolerance of a Topical Gel With 4% Quassia Extract in the Treatment of Rosacea".
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van Zuuren EJ, Fedorowicz Z (September 2015). "Interventions for rosacea: abridged updated Cochrane systematic review including GRADE assessments".
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Erythematotelangiectatic rosacea rosacea (also known as "vascular rosacea") is characterized by prominent history of prolonged (over 10 minutes)
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Elizabeth Lazaridou, Christina Giannopoulou, Christina Fotiadou, Eustratios Vakirlis, Anastasia Trigoni, Demetris Ioannides (November 2010).
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and inflammation, and may feel dry, irritated, or gritty. Other symptoms include foreign-body sensations, itching, burning, stinging, and
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The type of rosacea a person has informs the choice of treatment. Mild cases are often not treated at all, or are simply covered up with
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Tung RC, Bergfeld WF, Vidimos AT, Remzi BK (2000). "alpha-Hydroxy acid-based cosmetic procedures. Guidelines for patient management".
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mites have revealed that some people with rosacea have increased numbers of the mite, especially those with steroid-induced rosacea.
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Jansen T, Plewig G (1998). "Clinical and histological variants of rhinophyma, including nonsurgical treatment modalities".
875:(associated with birth defects). Contraception is required for women of child bearing age who are using these medications. 5586: 5002: 3865: 3556: 3393: 1018:
Rosacea affects around 5% of people worldwide. Incidence varies by ethnicity, and is particularly prevalent in those with
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play a role in rosacea. In a clinical study, ivermectin reduced lesions by 83% over 4 months, as compared to 74% under a
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Skin problems tend to be aggravated by particular trigger factors, that differ for different people. Common triggers are
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mites. When analyzing blood samples using a peripheral blood mononuclear cell proliferation assay, they discovered that
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telangiectasia, flushing, and papules. Quassia amara showed a sustained reduction of symptoms at 42 days of treatment.
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Managing pre-trigger events such as prolonged exposure to cool environments can directly influence warm-room flushing.
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Pyoderma faciale, also known as rosacea fulminans, is a conglobate, nodular disease that arises abruptly on the face.
750:. Eyes can become more susceptible to infection. About half of the people with subtypes 1–3 also have eye symptoms. 1657: 5491: 5459: 5287: 4770: 4702: 4506: 4366: 4361: 4135: 3855: 4396: 5481: 5172: 4466: 4057: 5386: 5370: 5184: 5042: 3900: 3546: 3483: 3378: 3007: 940: 905:
peels may help relieve redness caused by irritation, and reduce papules and pustules associated with rosacea.
626: 22: 5533: 2443: 5486: 5364: 5297: 5130: 4814: 4763: 4559: 4476: 4165: 3860: 3579: 3551: 3181: 3084: 3072: 622:(demodicidosis, also known as "mange" in animals) is a condition that may have a "rosacea-like" appearance. 161: 5381: 5075: 4992: 4910: 4900: 4687: 4682: 4431: 4140: 4052: 3368: 828: 807: 241: 228: 5551: 5466: 5329: 5282: 5222: 5125: 5012: 4775: 4647: 4526: 4376: 4042: 3969: 3657: 3191: 3171: 2486:"Microencapsulated Benzoyl Peroxide for Rosacea in Context: A Review of the Current Treatment Landscape" 1047: 683: 581: 561: 452: 448: 405: 404:
of the skin in symmetrical patches near the center of the face. Common signs can depend on age and sex:
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bacteria found in the mites could be responsible for the inflammation associated with the condition."
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have been used in the past to treat rosacea, but they may only work because they inhibit some SCTEs.
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Desai SR, Baldwin H, Del Rosso JQ, Gallo RL, Bhatia N, Harper JC, York JP, Gold LS (February 2024).
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Erythematotelangiectatic rosacea exhibits permanent redness (erythema) with a tendency to flush and
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In glandular rosacea, men with thick sebaceous skin predominate, a disease in which the papules are
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van Zuuren EJ, Fedorowicz Z, Tan J, van der Linden M, Arents B, Carter B, Charland L (July 2019).
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Tüzün Y, Wolf R, Kutlubay Z, Karakuş O, Engin B (February 2014). "Rosacea and rhinophyma".
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of rosacea. The treatment is based upon the hypothesis that parasitic mites of the genus
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Medications and topical irritants have also been known to trigger rosacea flares. Some
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van Zuuren EJ, Fedorowicz Z, Carter B, van der Linden MM, Charland L (28 April 2015).
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Hoting E, Paul E, Plewig G (December 1986). "Treatment of rosacea with isotretinoin".
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van Zuuren EJ, Fedorowicz Z, Carter B, van der Linden MM, Charland L (28 April 2015).
2346:"Burden of Disease: The Psychosocial Impact of Rosacea on a Patient's Quality of Life" 754:
is a rare complication which is characterized by blurry vision and vision loss as the
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Vieira AC, Mannis MJ (December 2013). "Ocular rosacea: common and commonly missed".
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While not curable, treatment usually improves symptoms. Treatment is typically with
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Evidence for the use of laser and intense pulsed-light therapy in rosacea is poor.
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mites may be a cause or exacerbating factor in rosacea. The researchers identified
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of the face. Many people experience stinging or burning pain and rarely itching.
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easily. Also small, widened blood vessels visible near the surface of the skin (
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Sand M, Sand D, Thrandorf C, Paech V, Altmeyer P, Bechara FG (4 June 2010).
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Four rosacea subtypes exist, and a patient may have more than one subtype:
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Wilkin J, Dahl M, Detmar M, Drake L, Liang MH, Odom R, Powell F (2004).
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Wilkin J, Dahl M, Detmar M, Drake L, Liang MH, Odom R, Powell F (2004).
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Moran EM, Foley R, Powell FC (2017). "Demodex and rosacea revisited".
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for swelling, mass, or bulb, and these can occur on the face and ears.
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and colleagues noticed that patients with rosacea had high levels of
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are often used for those with flushing due to rosacea. These include
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eye drops may help. Other treatments with tentative benefit include
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Rapini, Ronald P., Bolognia, Jean L., Jorizzo, Joseph L. (2007).
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heritage. Men and women are equally likely to develop rosacea.
956: 778:, with hemorrhagic nodular abscesses and indurated plaques. 112: 106: 97: 88: 959:, as well as in Europe, for the treatment of inflammatory 499:; after steroid withdrawal and photobiomodulation therapy 100: 1830:
JDDG: Journal der Deutschen Dermatologischen Gesellschaft
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and wrinkle treatments reported to cause rosacea include
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is common in men. Other signs include lumps on the skin (
1494:"Recent advances in understanding and managing rosacea" 654:(pimples) of subtype 2 rosacea. This suggests that the 2298: 2296: 2244: 2242: 2240: 1577:
James, William; Berger, Timothy; Elston, Dirk (2005).
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Rosacea conglobata is a severe rosacea that can mimic
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in the 1300s, and possibly as early as the 200s BC by
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Erythematotelangiectatic, papulopustular, phymatous,
94: 2959: 2251:"A Review of the Diagnosis and Treatment of Rosacea" 1316:"Rosacea: Epidemiology, pathogenesis, and treatment" 85: 5542: 5514: 5415: 5404: 5205: 5146: 5093: 5058: 4939: 4795: 4784: 4716: 4544: 4535: 4219: 4099: 4066: 4010: 3995: 3986: 3943: 3914: 3893: 3884: 3837: 3796: 3765: 3754: 3747: 3736: 3681: 3623: 3565: 3502: 3422: 3351: 3340: 3331: 3246: 3210: 3142: 3135: 3033: 2963: 2393:Searle T, Ali FR, Carolides S, Al-Niaimi F (2021). 2125: 1579:
Andrews' Diseases of the Skin: Clinical Dermatology
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Good evidence medications taken by mouth include 731:Phymatous rosacea is most commonly associated with 268: 255: 227: 217: 207: 199: 188: 180: 172: 160: 139: 127: 91: 73: 51: 46: 2123: 2121: 2119: 2117: 2115: 2113: 2111: 2109: 2107: 2105: 1772:Lacey N, Delaney S, Kavanagh K, Powell FC (2007). 1487: 1485: 1483: 1481: 1479: 1477: 1475: 1473: 1471: 742:, affected eyes and eyelids may appear red due to 439:light, heat, cold, or certain foods or beverages. 5228:Disseminate and recurrent infundibulofolliculitis 3130:Diseases of the skin and appendages by morphology 2399:The Journal of Clinical and Aesthetic Dermatology 556:-induced rosacea is caused by the use of topical 1982:Lookingbill and Marks' Principles of Dermatology 4327:Congenital onychodysplasia of the index fingers 2479: 2477: 2475: 2473: 2471: 2469: 2467: 2445:A Practical Understanding of Rosacea – part one 1677: 1675: 1605: 1603: 1601: 1599: 1597: 1595: 1363:Zouboulis CC, Katsambas AD, Kligman AM (2014). 842:Medications with good evidence include topical 515:(especially hot tea and coffee), foods high in 288:that typically affects the face. It results in 2632:Husein-ElAhmed H, Steinhoff M (January 2020). 1366:Pathogenesis and Treatment of Acne and Rosacea 5238:Erythromelanosis follicularis faciei et colli 4196: 3615:Pityriasis lichenoides et varioliformis acuta 3115: 2249:Noah Scheinfeld, Thomas Berk (January 2010). 2175:Fitzpatrick's Dermatology in General Medicine 2069: 2067: 1873:Celiker H, Toker E, Ergun T, Cinel L (2017). 324:on the face. Diagnosis is based on symptoms. 8: 3269:Dermatofibroma (benign fibrous histiocytoma) 2839:Journal of Clinical and Cosmetic Dermatology 2130:van Zuuren EJ (2 November 2017). "Rosacea". 1149: 1147: 1145: 1143: 1141: 1139: 882:class such as doxycycline, minocycline, and 2915:The Cochrane Database of Systematic Reviews 2546:The Cochrane Database of Systematic Reviews 1875:"An unusual presentation of ocular rosacea" 1545: 1543: 1541: 1539: 1137: 1135: 1133: 1131: 1129: 1127: 1125: 1123: 1121: 1119: 302:small and superficial dilated blood vessels 155:small and superficial dilated blood vessels 5412: 4792: 4541: 4203: 4189: 4181: 3992: 3890: 3762: 3751: 3744: 3348: 3337: 3139: 3122: 3108: 3100: 2960: 2535: 2533: 2531: 1573: 1571: 1207: 1205: 560:. These steroids are often prescribed for 60: 43: 2934: 2850: 2708: 2698: 2681:Siddiqui K, Stein Gold L, Gill J (2016). 2649: 2565: 2511: 2501: 2418: 2369: 2320: 2220: 1900: 1890: 1841: 1745: 1519: 1509: 1400:. Elsevier Health Sciences. p. 827. 1339: 1240: 1238: 1203: 1201: 1199: 1197: 1195: 1193: 1191: 1189: 1187: 1185: 1099: 1089: 823:recommended that those with rosacea wear 5233:Erosive pustular dermatosis of the scalp 4653:Central centrifugal cicatricial alopecia 2591:American Journal of Clinical Dermatology 2395:"Rosacea and Diet: What is New in 2021?" 2169: 2167: 2165: 2163: 2161: 1980:Marks, James G; Miller, Jeffery (2006). 1767: 1765: 641:as a distinct bacterium associated with 1414:from the original on 10 September 2017. 1383:from the original on 10 September 2017. 1303:from the original on 10 September 2017. 1064: 414:small and visible dilated blood vessels 5213:Acrokeratosis paraneoplastica of Bazex 3922:Disseminated intravascular coagulation 264:either by mouth or applied to the skin 2448:. Australian Sciences. Archived from 2303:Culp B, Scheinfeld N (January 2009). 1424:name="JAmAcadDermatol2004-Wilkin"> 1213:"Questions and Answers about Rosacea" 667:Small intestinal bacterial overgrowth 7: 5253:Intermittent hair–follicle dystrophy 2792:The Journal of Clinical Pharmacology 2289:from the original on 5 January 2011. 1879:Arquivos Brasileiros de Oftalmologia 1660:from the original on 7 December 2010 1314:Rainer BM, Kang S, Chien AL (2017). 459:, hot drinks, alcohol, spicy foods, 5190:Recurrent palmoplantar hidradenitis 5071:Idiopathic facial aseptic granuloma 4708:Marie Unna hereditary hypotrichosis 3094:Questions and Answers about Rosacea 2350:American Health & Drug Benefits 1492:Buddenkotte J, Steinhoff M (2018). 16:Skin condition, usually on the face 4931:Lupus miliaris disseminatus faciei 4678:Dissecting cellulitis of the scalp 3704:Postinflammatory hyperpigmentation 2880:10.1111/j.1365-4362.1986.tb04533.x 2746:10.1016/j.clindermatol.2016.10.014 2201:The British Journal of Dermatology 1654:New Zealand Dermatological Society 1581:. (10th ed.). Saunders. Page 245. 1247:The British Journal of Dermatology 1168:10.1016/j.clindermatol.2013.05.024 14: 5195:Neutrophilic eccrine hidradenitis 4954:Granulomatous perioral dermatitis 3605:Transient acantholytic dermatosis 1289:"Rosacea First choice treatments" 3714:Idiopathic guttate hypomelanosis 3082:Rosacea photo library at Dermnet 2603:10.2165/00128071-200001020-00002 1843:10.1111/j.1610-0387.2010.07513.x 1795:10.1111/j.1365-2133.2007.08028.x 1394:Schachner LA, Hansen RC (2011). 1223:from the original on 13 May 2017 1032: 629:-funded study demonstrated that 495:Topical steroid-induced rosacea 443:Erythematotelangiectatic rosacea 81: 69:Rosacea over the cheeks and nose 5355:Traumatic anserine folliculosis 5066:Granulomatous facial dermatitis 3724:Hypopigmented mycosis fungoides 2132:New England Journal of Medicine 1728:Baima B, Sticherling M (2002). 1074:"Cutaneous lesions of the nose" 934:α-2 adrenergic receptor agonist 785:characterized by overgrowth of 4372:Malalignment of the nail plate 3965:Lichen sclerosis et atrophicus 3673:Subcorneal pustular dermatosis 3299:Infantile digital fibromatosis 2927:10.1002/14651858.CD003262.pub5 2558:10.1002/14651858.CD003262.pub5 1782:British Journal of Dermatology 1511:10.12688/f1000research.16537.1 463:, cold or hot weather, or hot 400:Rosacea typically begins with 343:. When the eyes are affected, 1: 5003:Erythrotelangiectatic rosacea 3557:Epidermolysis bullosa simplex 3394:Langerhans cell histiocytosis 1610:Del Rosso JQ (October 2014). 1332:10.1080/19381980.2017.1361574 767:Variants of rosacea include: 538:, as well as high dosages of 367:may also be used. The use of 5258:Keratosis pilaris atropicans 5161:Folliculitis nares perforans 4033:Systemic lupus erythematosus 3788:Systemic lupus erythematosus 3479:Systemic lupus erythematosus 1628:10.1517/14656566.2014.945423 1397:Pediatric Dermatology E-Book 5028:Persistent edema of rosacea 3314:Lymphangioma circumscriptum 2911:"Interventions for rosacea" 2833:Diehl C, Ferrari A (2017). 2542:"Interventions for rosacea" 866:. Lesser evidence supports 5603: 5460:Postmiliarial hypohidrosis 5288:Menkes kinky hair syndrome 4703:Frontal fibrosing alopecia 4507:Staining of the nail plate 4367:Longitudinal erythronychia 4362:Lichen planus of the nails 4136:Mucous membrane pemphigoid 2503:10.1007/s40265-024-02003-w 2177:. (6th ed.). McGraw-Hill. 2173:Freedberg, et al. (2003). 2088:10.1016/j.jaad.2013.04.042 1953:10.1016/j.jaad.2004.01.048 1892:10.5935/0004-2749.20170097 1747:10.1080/000155502753600795 1734:Acta Dermato-Venereologica 1447:10.1016/j.jaad.2004.01.048 416:in older individuals, and 371:is typically recommended. 29: 20: 5345:Rubinstein–Taybi syndrome 5173:Pseudofolliculitis barbae 4467:Pterygium inversum unguis 2700:10.1186/s40064-016-2819-8 2003:"What Rosacea Looks Like" 1984:(4th ed.). Elsevier Inc. 1730:"Demodicidosis revisited" 1552:Dermatology: 2-Volume Set 1369:. Springer. p. XXV. 604:Demodex folliculitis and 584:, and elevated levels of 412:are common in the young, 68: 59: 5387:Uncombable hair syndrome 5371:Trichorrhexis invaginata 5185:Hidradenitis suppurativa 5043:Periorificial dermatitis 3901:Thrombocytopenic purpura 3547:Dermatitis herpetiformis 3532:Acute contact dermatitis 3484:Pityriasis rubra pilaris 3409:Wiskott–Aldrich syndrome 3379:Lichen simplex chronicus 3259:Epidermal inclusion cyst 2804:10.1177/0091270010391533 2267:10.3810/pgm.2010.01.2107 1616:Expert Opin Pharmacother 1078:Head & Face Medicine 627:National Rosacea Society 30:Not to be confused with 23:Rosacea (disambiguation) 5365:Trichomycosis axillaris 5298:Parakeratosis pustulosa 4815:Acne miliaris necrotica 4596:(male-pattern baldness) 4560:noncicatricial alopecia 4477:Purpura of the nail bed 4166:Squamous-cell carcinoma 4161:Systemic histoplasmosis 3552:Porphyria cutanea tarda 3182:Squamous-cell carcinoma 3087:26 October 2011 at the 2082:(6 (Suppl 1)): S36–41. 1293:Prescrire International 932:or dizziness. The oral 781:Phymatous rosacea is a 612:Studies of rosacea and 396:Commonly affected zones 5382:Trichostasis spinulosa 5076:Periorbital dermatitis 4993:Papulopustular rosacea 4911:Acne with facial edema 4901:Acne keloidalis nuchae 4688:Folliculitis decalvans 4683:Graham-Little syndrome 4432:Onychoptosis defluvium 4141:Cicatricial pemphigoid 4058:Acne keloidalis nuchae 4053:Folliculitis decalvans 2852:10.16966/2576-2826.117 2042:10.1055/s-2008-1064456 1156:Clinics in Dermatology 829:sodium laureth sulfate 710: 699: 503: 397: 242:seborrhoeic dermatitis 229:Differential diagnosis 5552:Sebaceous hyperplasia 5467:Granulosis rubra nasi 5330:Pityriasis amiantacea 5283:Loose anagen syndrome 5223:Bubble hair deformity 5013:Gram-negative rosacea 4776:Nevoid hypertrichosis 4648:Pseudopelade of Brocq 4527:Twenty-nail dystrophy 4397:Nail–patella syndrome 4377:Median nail dystrophy 4043:Loose anagen syndrome 3970:Necrobiosis lipoidica 3906:Actinic/solar purpura 3580:Insect bite reactions 3369:Seborrheic dermatitis 3192:Merkel-cell carcinoma 3172:Molluscum contagiosum 2255:Postgraduate Medicine 2144:10.1056/NEJMcp1506630 1299:: 126–128. May 2017. 1091:10.1186/1746-160X-6-7 1048:Seborrheic dermatitis 705: 697: 684:seborrheic dermatitis 582:antimicrobial peptide 562:seborrheic dermatitis 494: 395: 5587:Cutaneous conditions 5435:Miliaria crystalline 5376:Trichorrhexis nodosa 4643:cicatricial alopecia 4625:Alopecia neoplastica 4620:Trichorrhexis nodosa 4248:Yellow nail syndrome 3866:Annulare centrifugum 3389:Glucagonoma syndrome 3187:Basal-cell carcinoma 3162:Seborrheic keratosis 2442:Dahl, Colin (2008). 1970:on 27 February 2007. 1554:. St. Louis: Mosby. 1464:on 27 February 2007. 748:sensitivity to light 632:Demodex folliculorum 620:Demodex folliculitis 451:reaction to various 418:swelling of the nose 402:reddening (flushing) 377:The Canterbury Tales 318:psychological stress 21:For other uses, see 5577:Acneiform eruptions 5534:Fox–Fordyce disease 5319:Pili pseudoannulati 5273:Lichen planopilaris 5248:Hair follicle nevus 5166:Tufted folliculitis 4949:Perioral dermatitis 4698:Triangular alopecia 4615:Lichen planopilaris 4594:Androgenic alopecia 4497:Splinter hemorrhage 4492:Shell nail syndrome 4337:Half and half nails 4111:Aphthous stomatitis 4048:Lichen planopilaris 4023:Androgenic alopecia 3829:Fixed drug eruption 3404:Pemphigus foliaceus 3304:Granular cell tumor 2778:on 22 January 2015. 2305:"Rosacea: a review" 783:cutaneous condition 698:Rosacea on the face 662:Intestinal bacteria 410:red swollen patches 238:perioral dermatitis 5455:Occlusion miliaria 5445:Miliaria pustulosa 5335:Plica neuropathica 5033:Rosacea conglobata 4844:Acne medicamentosa 4663:Traumatic alopecia 4517:Subungual hematoma 4131:Pemphigus vulgaris 3960:Granuloma annulare 3824:Carcinoid syndrome 3709:Tuberous sclerosis 3668:Coccidioidomycosis 3542:Bullous pemphigoid 3537:Pemphigus vulgaris 3469:Secondary syphilis 3359:Contact dermatitis 3034:External resources 2076:J Am Acad Dermatol 2009:on 4 February 2013 1941:J Am Acad Dermatol 1435:J Am Acad Dermatol 926:low blood pressure 903:alpha-hydroxy acid 711: 700: 638:Bacillus oleronius 504: 398: 388:Signs and symptoms 5564: 5563: 5560: 5559: 5440:Miliaria profunda 5400: 5399: 5392:Woolly hair nevus 5278:Lichen spinulosus 5116:Trichilemmal cyst 5089: 5088: 5008:Glandular rosacea 4961:Phymatous rosacea 4891:Occupational acne 4673:Hot comb alopecia 4658:Pressure alopecia 4635:Alopecia mucinosa 4610:Traction alopecia 4605:Telogen effluvium 4178: 4177: 4174: 4173: 4018:Telogen effluvium 3982: 3981: 3978: 3977: 3939: 3938: 3935: 3934: 3880: 3879: 3732: 3731: 3600:Lichen spinulosus 3595:Keratosis pilaris 3474:Mycosis fungoides 3374:Stasis dermatitis 3364:Atopic dermatitis 3327: 3326: 3202:Trichoepithelioma 3177:Actinic keratosis 3068: 3067: 2651:10.1111/dth.13203 2344:Huynh TT (2013). 2213:10.1111/bjd.17590 2138:(18): 1754–1764. 2030:Facial Plast Surg 1561:978-1-4160-2999-1 1407:978-0-7234-3665-2 1376:978-3-540-69375-8 1320:Dermatoendocrinol 1259:10.1111/bjd.13956 1217:www.niams.nih.gov 1053:Keratosis pilaris 532:microdermabrasion 475:Glandular rosacea 276: 275: 223:Based on symptoms 219:Diagnostic method 41:Medical condition 5594: 5413: 5350:Setleis syndrome 5314:Pili multigemini 5048:Pyoderma faciale 4793: 4630:Anagen effluvium 4542: 4472:Pterygium unguis 4392:Muehrcke's lines 4279:Onychotillomania 4205: 4198: 4191: 4182: 4116:Oral candidiasis 3993: 3891: 3819:Erythema nodosum 3763: 3752: 3745: 3689:Tinea versicolor 3527:Bullous impetigo 3464:Pityriasis rosea 3399:Lichen sclerosus 3384:Darier's disease 3349: 3338: 3294:Kaposi's sarcoma 3140: 3124: 3117: 3110: 3101: 2961: 2949: 2948: 2938: 2906: 2900: 2899: 2863: 2857: 2856: 2854: 2830: 2824: 2823: 2787: 2781: 2779: 2774:. Archived from 2764: 2758: 2757: 2729: 2723: 2722: 2712: 2702: 2678: 2672: 2671: 2653: 2629: 2623: 2622: 2586: 2580: 2579: 2569: 2537: 2526: 2525: 2515: 2505: 2481: 2462: 2461: 2459: 2457: 2452:on 21 March 2008 2439: 2433: 2432: 2422: 2390: 2384: 2383: 2373: 2341: 2335: 2334: 2324: 2300: 2291: 2290: 2246: 2235: 2234: 2224: 2192: 2186: 2171: 2156: 2155: 2127: 2100: 2099: 2071: 2062: 2061: 2025: 2019: 2018: 2016: 2014: 2005:. Archived from 1999: 1993: 1978: 1972: 1971: 1969: 1963:. Archived from 1938: 1929: 1923: 1922: 1904: 1894: 1870: 1864: 1863: 1845: 1821: 1815: 1814: 1778: 1769: 1760: 1759: 1749: 1725: 1719: 1718: 1679: 1670: 1669: 1667: 1665: 1646: 1640: 1639: 1607: 1590: 1575: 1566: 1565: 1547: 1534: 1533: 1523: 1513: 1489: 1466: 1465: 1463: 1457:. Archived from 1432: 1422: 1416: 1415: 1391: 1385: 1384: 1360: 1354: 1353: 1343: 1311: 1305: 1304: 1285: 1279: 1278: 1242: 1233: 1232: 1230: 1228: 1209: 1180: 1179: 1151: 1114: 1113: 1103: 1093: 1069: 1042: 1037: 1036: 1035: 808:normal cosmetics 787:sebaceous glands 544:benzoyl peroxide 457:emotional stress 119: 118: 115: 114: 109: 108: 103: 102: 99: 96: 93: 90: 87: 64: 44: 32:pityriasis rosea 5602: 5601: 5597: 5596: 5595: 5593: 5592: 5591: 5567: 5566: 5565: 5556: 5538: 5510: 5407: 5396: 5369:Trichorrhexis ( 5201: 5142: 5111:Epidermoid cyst 5085: 5054: 5018:Steroid rosacea 4935: 4896:Acne aestivalis 4834:Excoriated acne 4810:Acne conglobata 4787: 4780: 4712: 4549: 4531: 4502:Spotted lunulae 4462:Psoriatic nails 4417:Onychomatricoma 4230:Onychogryphosis 4215: 4213:skin appendages 4209: 4179: 4170: 4102: 4095: 4062: 4028:Alopecia areata 4006: 3988: 3974: 3931: 3910: 3886: 3876: 3833: 3792: 3778:Viral exanthems 3756: 3740: 3738: 3728: 3699:Pityriasis alba 3677: 3619: 3561: 3498: 3418: 3414:Zinc deficiency 3344: 3342: 3323: 3251: 3242: 3206: 3197:Nevus sebaceous 3131: 3128: 3089:Wayback Machine 3069: 3064: 3063: 3029: 3028: 2972: 2958: 2953: 2952: 2921:(4): CD003262. 2908: 2907: 2903: 2865: 2864: 2860: 2832: 2831: 2827: 2789: 2788: 2784: 2766: 2765: 2761: 2731: 2730: 2726: 2680: 2679: 2675: 2631: 2630: 2626: 2588: 2587: 2583: 2552:(4): CD003262. 2539: 2538: 2529: 2483: 2482: 2465: 2455: 2453: 2441: 2440: 2436: 2392: 2391: 2387: 2343: 2342: 2338: 2302: 2301: 2294: 2248: 2247: 2238: 2194: 2193: 2189: 2172: 2159: 2129: 2128: 2103: 2073: 2072: 2065: 2027: 2026: 2022: 2012: 2010: 2001: 2000: 1996: 1979: 1975: 1967: 1936: 1931: 1930: 1926: 1872: 1871: 1867: 1823: 1822: 1818: 1776: 1771: 1770: 1763: 1727: 1726: 1722: 1686:Nature Medicine 1681: 1680: 1673: 1663: 1661: 1648: 1647: 1643: 1622:(14): 2029–38. 1609: 1608: 1593: 1576: 1569: 1562: 1549: 1548: 1537: 1491: 1490: 1469: 1461: 1430: 1425: 1423: 1419: 1408: 1393: 1392: 1388: 1377: 1362: 1361: 1357: 1326:(1): e1361574. 1313: 1312: 1308: 1287: 1286: 1282: 1244: 1243: 1236: 1226: 1224: 1211: 1210: 1183: 1153: 1152: 1117: 1071: 1070: 1066: 1061: 1040:Medicine portal 1038: 1033: 1031: 1028: 1016: 1007: 999: 884:oxytetracycline 840: 820: 804: 776:acne conglobata 765: 744:telangiectasias 723:telangiectasias 692: 675: 664: 610: 586:stratum corneum 570: 489: 477: 445: 390: 246:dermatomyositis 176:30–50 years old 123: 111: 105: 84: 80: 42: 39: 26: 17: 12: 11: 5: 5600: 5598: 5590: 5589: 5584: 5579: 5569: 5568: 5562: 5561: 5558: 5557: 5555: 5554: 5548: 5546: 5540: 5539: 5537: 5536: 5531: 5526: 5520: 5518: 5512: 5511: 5509: 5508: 5507: 5506: 5496: 5495: 5494: 5489: 5484: 5474: 5472:Ross' syndrome 5469: 5464: 5463: 5462: 5457: 5452: 5450:Miliaria rubra 5447: 5442: 5437: 5432: 5430:Colloid milium 5421: 5419: 5410: 5402: 5401: 5398: 5397: 5395: 5394: 5389: 5384: 5379: 5373: 5367: 5362: 5357: 5352: 5347: 5342: 5337: 5332: 5327: 5321: 5316: 5311: 5309:Pili bifurcati 5306: 5300: 5295: 5290: 5285: 5280: 5275: 5270: 5268:Koenen's tumor 5265: 5260: 5255: 5250: 5245: 5240: 5235: 5230: 5225: 5220: 5218:Acroosteolysis 5215: 5209: 5207: 5203: 5202: 5200: 5199: 5198: 5197: 5192: 5187: 5176: 5175: 5170: 5169: 5168: 5163: 5152: 5150: 5144: 5143: 5141: 5140: 5135: 5134: 5133: 5128: 5122:Steatocystoma 5120: 5119: 5118: 5113: 5105:Sebaceous cyst 5100: 5098: 5091: 5090: 5087: 5086: 5084: 5083: 5081:SAPHO syndrome 5078: 5073: 5068: 5062: 5060: 5056: 5055: 5053: 5052: 5051: 5050: 5045: 5035: 5030: 5025: 5023:Ocular rosacea 5020: 5015: 5010: 5005: 5000: 4998:Lupoid rosacea 4995: 4990: 4989: 4988: 4983: 4978: 4973: 4968: 4958: 4957: 4956: 4945: 4943: 4937: 4936: 4934: 4933: 4928: 4923: 4921:Acne necrotica 4918: 4913: 4908: 4906:Acne mechanica 4903: 4898: 4893: 4888: 4886:Acne cosmetica 4883: 4878: 4873: 4872: 4871: 4866: 4861: 4851: 4841: 4839:Acne fulminans 4836: 4831: 4825:Infantile acne 4822: 4817: 4812: 4807: 4801: 4799: 4790: 4782: 4781: 4779: 4778: 4773: 4768: 4767: 4766: 4761: 4756: 4748: 4747: 4746: 4741: 4736: 4728: 4722: 4720: 4718:Hypertrichosis 4714: 4713: 4711: 4710: 4705: 4700: 4691: 4690: 4685: 4680: 4675: 4670: 4668:Tumor alopecia 4665: 4660: 4655: 4650: 4638: 4637: 4632: 4627: 4622: 4617: 4612: 4607: 4602: 4597: 4590: 4589: 4588: 4587: 4582: 4577: 4572: 4555: 4553: 4539: 4533: 4532: 4530: 4529: 4524: 4519: 4514: 4512:Stippled nails 4509: 4504: 4499: 4494: 4489: 4484: 4479: 4474: 4469: 4464: 4459: 4457:Plummer's nail 4454: 4449: 4444: 4439: 4434: 4429: 4424: 4419: 4414: 4409: 4404: 4399: 4394: 4389: 4384: 4379: 4374: 4369: 4364: 4359: 4354: 4349: 4344: 4339: 4334: 4329: 4324: 4319: 4318: 4317: 4312: 4300: 4299: 4294: 4287: 4286: 4281: 4274: 4273: 4268: 4261: 4260: 4255: 4250: 4245: 4238: 4237: 4232: 4225: 4223: 4217: 4216: 4210: 4208: 4207: 4200: 4193: 4185: 4176: 4175: 4172: 4171: 4169: 4168: 4163: 4158: 4153: 4151:Coxsackievirus 4148: 4143: 4138: 4133: 4128: 4123: 4118: 4113: 4107: 4105: 4097: 4096: 4094: 4093: 4088: 4083: 4078: 4072: 4070: 4064: 4063: 4061: 4060: 4055: 4050: 4045: 4040: 4035: 4030: 4025: 4020: 4014: 4012: 4008: 4007: 4005: 4004: 4001: 3999: 3990: 3984: 3983: 3980: 3979: 3976: 3975: 3973: 3972: 3967: 3962: 3957: 3947: 3945: 3941: 3940: 3937: 3936: 3933: 3932: 3930: 3929: 3924: 3918: 3916: 3912: 3911: 3909: 3908: 3903: 3897: 3895: 3888: 3882: 3881: 3878: 3877: 3875: 3874: 3868: 3863: 3861:Gyratum repens 3858: 3853: 3847: 3841: 3839: 3835: 3834: 3832: 3831: 3826: 3821: 3816: 3811: 3806: 3800: 3798: 3794: 3793: 3791: 3790: 3785: 3783:Toxic erythema 3780: 3775: 3773:Drug eruptions 3769: 3767: 3760: 3749: 3742: 3734: 3733: 3730: 3729: 3727: 3726: 3721: 3716: 3711: 3706: 3701: 3696: 3691: 3685: 3683: 3679: 3678: 3676: 3675: 3670: 3665: 3660: 3655: 3650: 3645: 3640: 3635: 3629: 3627: 3621: 3620: 3618: 3617: 3612: 3610:Lichen nitidus 3607: 3602: 3597: 3592: 3587: 3582: 3577: 3571: 3569: 3563: 3562: 3560: 3559: 3554: 3549: 3544: 3539: 3534: 3529: 3524: 3519: 3514: 3512:Herpes simplex 3508: 3506: 3500: 3499: 3497: 3496: 3491: 3486: 3481: 3476: 3471: 3466: 3461: 3455: 3450: 3445: 3440: 3434: 3428: 3426: 3420: 3419: 3417: 3416: 3411: 3406: 3401: 3396: 3391: 3386: 3381: 3376: 3371: 3366: 3361: 3355: 3353: 3346: 3335: 3329: 3328: 3325: 3324: 3322: 3321: 3316: 3311: 3306: 3301: 3296: 3291: 3286: 3281: 3276: 3271: 3266: 3261: 3255: 3253: 3244: 3243: 3241: 3240: 3235: 3230: 3225: 3220: 3214: 3212: 3208: 3207: 3205: 3204: 3199: 3194: 3189: 3184: 3179: 3174: 3169: 3164: 3159: 3154: 3148: 3146: 3137: 3133: 3132: 3129: 3127: 3126: 3119: 3112: 3104: 3098: 3097: 3091: 3079: 3066: 3065: 3062: 3061: 3050: 3038: 3037: 3035: 3031: 3030: 3027: 3026: 3015: 3004: 2989: 2973: 2968: 2967: 2965: 2964:Classification 2957: 2956:External links 2954: 2951: 2950: 2901: 2868:Int J Dermatol 2858: 2825: 2782: 2759: 2740:(2): 195–200. 2734:Clin. Dermatol 2724: 2673: 2624: 2581: 2527: 2496:(3): 275–284. 2463: 2434: 2385: 2356:(6): 348–354. 2336: 2292: 2236: 2187: 2157: 2101: 2063: 2020: 1994: 1973: 1924: 1885:(6): 396–398. 1865: 1816: 1789:(3): 474–481. 1761: 1720: 1699:10.1038/nm1616 1671: 1641: 1591: 1567: 1560: 1535: 1467: 1417: 1406: 1386: 1375: 1355: 1306: 1280: 1234: 1219:. April 2016. 1181: 1115: 1063: 1062: 1060: 1057: 1056: 1055: 1050: 1044: 1043: 1027: 1024: 1015: 1012: 1006: 1003: 998: 995: 949:xylometazoline 941:alpha agonists 930:low heart rate 839: 836: 819: 816: 803: 800: 799: 798: 779: 772: 764: 761: 760: 759: 740:ocular rosacea 736: 729: 726: 691: 690:Classification 688: 674: 671: 663: 660: 609: 602: 569: 566: 536:chemical peels 488: 485: 476: 473: 444: 441: 389: 386: 286:skin condition 274: 273: 270: 266: 265: 259: 253: 252: 231: 225: 224: 221: 215: 214: 213:Family history 211: 205: 204: 201: 197: 196: 190: 186: 185: 182: 178: 177: 174: 170: 169: 164: 158: 157: 143: 137: 136: 131: 125: 124: 122: 121: 77: 75: 71: 70: 66: 65: 57: 56: 53: 49: 48: 40: 15: 13: 10: 9: 6: 4: 3: 2: 5599: 5588: 5585: 5583: 5580: 5578: 5575: 5574: 5572: 5553: 5550: 5549: 5547: 5545: 5541: 5535: 5532: 5530: 5529:Chromhidrosis 5527: 5525: 5522: 5521: 5519: 5517: 5513: 5505: 5502: 5501: 5500: 5497: 5493: 5490: 5488: 5485: 5483: 5480: 5479: 5478: 5477:Hyperhidrosis 5475: 5473: 5470: 5468: 5465: 5461: 5458: 5456: 5453: 5451: 5448: 5446: 5443: 5441: 5438: 5436: 5433: 5431: 5428: 5427: 5426: 5423: 5422: 5420: 5418: 5414: 5411: 5409: 5403: 5393: 5390: 5388: 5385: 5383: 5380: 5377: 5374: 5372: 5368: 5366: 5363: 5361: 5358: 5356: 5353: 5351: 5348: 5346: 5343: 5341: 5338: 5336: 5333: 5331: 5328: 5325: 5322: 5320: 5317: 5315: 5312: 5310: 5307: 5305: 5304:Pili annulati 5301: 5299: 5296: 5294: 5291: 5289: 5286: 5284: 5281: 5279: 5276: 5274: 5271: 5269: 5266: 5264: 5261: 5259: 5256: 5254: 5251: 5249: 5246: 5244: 5241: 5239: 5236: 5234: 5231: 5229: 5226: 5224: 5221: 5219: 5216: 5214: 5211: 5210: 5208: 5204: 5196: 5193: 5191: 5188: 5186: 5183: 5182: 5181: 5178: 5177: 5174: 5171: 5167: 5164: 5162: 5159: 5158: 5157: 5154: 5153: 5151: 5149: 5145: 5139: 5136: 5132: 5129: 5127: 5124: 5123: 5121: 5117: 5114: 5112: 5109: 5108: 5106: 5102: 5101: 5099: 5097: 5092: 5082: 5079: 5077: 5074: 5072: 5069: 5067: 5064: 5063: 5061: 5057: 5049: 5046: 5044: 5041: 5040: 5039: 5036: 5034: 5031: 5029: 5026: 5024: 5021: 5019: 5016: 5014: 5011: 5009: 5006: 5004: 5001: 4999: 4996: 4994: 4991: 4987: 4984: 4982: 4979: 4977: 4974: 4972: 4971:Blepharophyma 4969: 4967: 4964: 4963: 4962: 4959: 4955: 4952: 4951: 4950: 4947: 4946: 4944: 4942: 4938: 4932: 4929: 4927: 4924: 4922: 4919: 4917: 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4892: 4889: 4887: 4884: 4882: 4879: 4877: 4874: 4870: 4867: 4865: 4862: 4860: 4857: 4856: 4855: 4852: 4849: 4845: 4842: 4840: 4837: 4835: 4832: 4830: 4829:Neonatal acne 4826: 4823: 4821: 4820:Tropical acne 4818: 4816: 4813: 4811: 4808: 4806: 4805:Acne vulgaris 4803: 4802: 4800: 4798: 4794: 4791: 4789: 4783: 4777: 4774: 4772: 4769: 4765: 4762: 4760: 4757: 4755: 4752: 4751: 4749: 4745: 4742: 4740: 4737: 4735: 4732: 4731: 4729: 4727: 4724: 4723: 4721: 4719: 4715: 4709: 4706: 4704: 4701: 4699: 4696: 4693: 4692: 4689: 4686: 4684: 4681: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4659: 4656: 4654: 4651: 4649: 4646: 4644: 4640: 4639: 4636: 4633: 4631: 4628: 4626: 4623: 4621: 4618: 4616: 4613: 4611: 4608: 4606: 4603: 4601: 4600:Hypotrichosis 4598: 4595: 4592: 4591: 4586: 4583: 4581: 4578: 4576: 4573: 4571: 4568: 4567: 4566: 4563: 4561: 4557: 4556: 4554: 4552: 4547: 4543: 4540: 4538: 4534: 4528: 4525: 4523: 4522:Terry's nails 4520: 4518: 4515: 4513: 4510: 4508: 4505: 4503: 4500: 4498: 4495: 4493: 4490: 4488: 4485: 4483: 4480: 4478: 4475: 4473: 4470: 4468: 4465: 4463: 4460: 4458: 4455: 4453: 4450: 4448: 4445: 4443: 4442:Onychoschizia 4440: 4438: 4437:Onychorrhexis 4435: 4433: 4430: 4428: 4425: 4423: 4422:Onychomycosis 4420: 4418: 4415: 4413: 4412:Onychomadesis 4410: 4408: 4405: 4403: 4402:Onychoatrophy 4400: 4398: 4395: 4393: 4390: 4388: 4385: 4383: 4380: 4378: 4375: 4373: 4370: 4368: 4365: 4363: 4360: 4358: 4355: 4353: 4350: 4348: 4345: 4343: 4340: 4338: 4335: 4333: 4330: 4328: 4325: 4323: 4320: 4316: 4313: 4311: 4308: 4307: 4306: 4302: 4301: 4298: 4295: 4293: 4289: 4288: 4285: 4282: 4280: 4276: 4275: 4272: 4271:Nail clubbing 4269: 4267: 4263: 4262: 4259: 4256: 4254: 4251: 4249: 4246: 4244: 4240: 4239: 4236: 4233: 4231: 4227: 4226: 4224: 4222: 4218: 4214: 4211:Disorders of 4206: 4201: 4199: 4194: 4192: 4187: 4186: 4183: 4167: 4164: 4162: 4159: 4157: 4154: 4152: 4149: 4147: 4144: 4142: 4139: 4137: 4134: 4132: 4129: 4127: 4124: 4122: 4121:Lichen planus 4119: 4117: 4114: 4112: 4109: 4108: 4106: 4104: 4098: 4092: 4089: 4087: 4084: 4082: 4079: 4077: 4076:Onychomycosis 4074: 4073: 4071: 4069: 4065: 4059: 4056: 4054: 4051: 4049: 4046: 4044: 4041: 4039: 4038:Tinea capitis 4036: 4034: 4031: 4029: 4026: 4024: 4021: 4019: 4016: 4015: 4013: 4009: 4003: 4002: 4000: 3998: 3994: 3991: 3987:Miscellaneous 3985: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3952: 3949: 3948: 3946: 3942: 3928: 3925: 3923: 3920: 3919: 3917: 3913: 3907: 3904: 3902: 3899: 3898: 3896: 3892: 3889: 3885:Nonblanchable 3883: 3872: 3869: 3867: 3864: 3862: 3859: 3857: 3854: 3852: 3848: 3846: 3843: 3842: 3840: 3836: 3830: 3827: 3825: 3822: 3820: 3817: 3815: 3812: 3810: 3807: 3805: 3802: 3801: 3799: 3795: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3770: 3768: 3764: 3761: 3759: 3753: 3750: 3746: 3743: 3735: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3705: 3702: 3700: 3697: 3695: 3692: 3690: 3687: 3686: 3684: 3682:Hypopigmented 3680: 3674: 3671: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3649: 3646: 3644: 3641: 3639: 3636: 3634: 3633:Acne vulgaris 3631: 3630: 3628: 3626: 3622: 3616: 3613: 3611: 3608: 3606: 3603: 3601: 3598: 3596: 3593: 3591: 3588: 3586: 3585:Lichen planus 3583: 3581: 3578: 3576: 3573: 3572: 3570: 3568: 3564: 3558: 3555: 3553: 3550: 3548: 3545: 3543: 3540: 3538: 3535: 3533: 3530: 3528: 3525: 3523: 3520: 3518: 3517:Herpes zoster 3515: 3513: 3510: 3509: 3507: 3505: 3501: 3495: 3492: 3490: 3489:Parapsoriasis 3487: 3485: 3482: 3480: 3477: 3475: 3472: 3470: 3467: 3465: 3462: 3459: 3456: 3454: 3451: 3449: 3446: 3444: 3441: 3439: 3435: 3433: 3430: 3429: 3427: 3425: 3421: 3415: 3412: 3410: 3407: 3405: 3402: 3400: 3397: 3395: 3392: 3390: 3387: 3385: 3382: 3380: 3377: 3375: 3372: 3370: 3367: 3365: 3362: 3360: 3357: 3356: 3354: 3350: 3347: 3339: 3336: 3334: 3330: 3320: 3317: 3315: 3312: 3310: 3307: 3305: 3302: 3300: 3297: 3295: 3292: 3290: 3287: 3285: 3282: 3280: 3277: 3275: 3272: 3270: 3267: 3265: 3262: 3260: 3257: 3256: 3254: 3249: 3245: 3239: 3236: 3234: 3231: 3229: 3226: 3224: 3221: 3219: 3216: 3215: 3213: 3209: 3203: 3200: 3198: 3195: 3193: 3190: 3188: 3185: 3183: 3180: 3178: 3175: 3173: 3170: 3168: 3165: 3163: 3160: 3158: 3155: 3153: 3150: 3149: 3147: 3145: 3141: 3138: 3134: 3125: 3120: 3118: 3113: 3111: 3106: 3105: 3102: 3095: 3092: 3090: 3086: 3083: 3080: 3078: 3074: 3071: 3070: 3060: 3056: 3055: 3051: 3049: 3045: 3044: 3040: 3039: 3036: 3032: 3025: 3021: 3020: 3016: 3014: 3010: 3009: 3005: 3003: 2999: 2998: 2994: 2990: 2988: 2984: 2983: 2979: 2975: 2974: 2971: 2966: 2962: 2955: 2946: 2942: 2937: 2932: 2928: 2924: 2920: 2916: 2912: 2905: 2902: 2897: 2893: 2889: 2885: 2881: 2877: 2874:(10): 660–3. 2873: 2869: 2862: 2859: 2853: 2848: 2844: 2840: 2836: 2829: 2826: 2821: 2817: 2813: 2809: 2805: 2801: 2797: 2793: 2786: 2783: 2777: 2773: 2769: 2763: 2760: 2755: 2751: 2747: 2743: 2739: 2735: 2728: 2725: 2720: 2716: 2711: 2706: 2701: 2696: 2692: 2688: 2684: 2677: 2674: 2669: 2665: 2661: 2657: 2652: 2647: 2644:(1): e13203. 2643: 2639: 2638:Dermatol Ther 2635: 2628: 2625: 2620: 2616: 2612: 2608: 2604: 2600: 2596: 2592: 2585: 2582: 2577: 2573: 2568: 2563: 2559: 2555: 2551: 2547: 2543: 2536: 2534: 2532: 2528: 2523: 2519: 2514: 2509: 2504: 2499: 2495: 2491: 2487: 2480: 2478: 2476: 2474: 2472: 2470: 2468: 2464: 2451: 2447: 2446: 2438: 2435: 2430: 2426: 2421: 2416: 2412: 2408: 2405:(12): 49–54. 2404: 2400: 2396: 2389: 2386: 2381: 2377: 2372: 2367: 2363: 2359: 2355: 2351: 2347: 2340: 2337: 2332: 2328: 2323: 2318: 2314: 2310: 2306: 2299: 2297: 2293: 2288: 2284: 2280: 2276: 2272: 2268: 2264: 2261:(1): 139–43. 2260: 2256: 2252: 2245: 2243: 2241: 2237: 2232: 2228: 2223: 2218: 2214: 2210: 2206: 2202: 2198: 2191: 2188: 2184: 2183:0-07-138076-0 2180: 2176: 2170: 2168: 2166: 2164: 2162: 2158: 2153: 2149: 2145: 2141: 2137: 2133: 2126: 2124: 2122: 2120: 2118: 2116: 2114: 2112: 2110: 2108: 2106: 2102: 2097: 2093: 2089: 2085: 2081: 2077: 2070: 2068: 2064: 2059: 2055: 2051: 2047: 2043: 2039: 2036:(4): 241–53. 2035: 2031: 2024: 2021: 2008: 2004: 1998: 1995: 1991: 1990:1-4160-3185-5 1987: 1983: 1977: 1974: 1968:(PDF reprint) 1966: 1962: 1958: 1954: 1950: 1947:(6): 907–12. 1946: 1942: 1935: 1928: 1925: 1920: 1916: 1912: 1908: 1903: 1898: 1893: 1888: 1884: 1880: 1876: 1869: 1866: 1861: 1857: 1853: 1849: 1844: 1839: 1835: 1831: 1827: 1820: 1817: 1812: 1808: 1804: 1800: 1796: 1792: 1788: 1784: 1783: 1775: 1768: 1766: 1762: 1757: 1753: 1748: 1743: 1739: 1735: 1731: 1724: 1721: 1716: 1712: 1708: 1704: 1700: 1696: 1693:(8): 975–80. 1692: 1688: 1687: 1683:in rosacea". 1678: 1676: 1672: 1659: 1655: 1651: 1645: 1642: 1637: 1633: 1629: 1625: 1621: 1617: 1613: 1606: 1604: 1602: 1600: 1598: 1596: 1592: 1588: 1587:0-7216-2921-0 1584: 1580: 1574: 1572: 1568: 1563: 1557: 1553: 1546: 1544: 1542: 1540: 1536: 1531: 1527: 1522: 1517: 1512: 1507: 1503: 1499: 1495: 1488: 1486: 1484: 1482: 1480: 1478: 1476: 1474: 1472: 1468: 1462:(PDF reprint) 1460: 1456: 1452: 1448: 1444: 1441:(6): 907–12. 1440: 1436: 1429: 1421: 1418: 1413: 1409: 1403: 1399: 1398: 1390: 1387: 1382: 1378: 1372: 1368: 1367: 1359: 1356: 1351: 1347: 1342: 1337: 1333: 1329: 1325: 1321: 1317: 1310: 1307: 1302: 1298: 1294: 1290: 1284: 1281: 1276: 1272: 1268: 1264: 1260: 1256: 1253:(3): 651–62. 1252: 1248: 1241: 1239: 1235: 1222: 1218: 1214: 1208: 1206: 1204: 1202: 1200: 1198: 1196: 1194: 1192: 1190: 1188: 1186: 1182: 1177: 1173: 1169: 1165: 1161: 1157: 1150: 1148: 1146: 1144: 1142: 1140: 1138: 1136: 1134: 1132: 1130: 1128: 1126: 1124: 1122: 1120: 1116: 1111: 1107: 1102: 1097: 1092: 1087: 1083: 1079: 1075: 1068: 1065: 1058: 1054: 1051: 1049: 1046: 1045: 1041: 1030: 1025: 1023: 1021: 1013: 1011: 1004: 1002: 996: 994: 990: 986: 984: 979: 975: 972: 971:metronidazole 968: 967: 962: 958: 952: 950: 946: 945:oxymetazoline 942: 938: 935: 931: 927: 923: 919: 915: 911: 910:Beta-blockers 906: 904: 899: 895: 891: 887: 885: 881: 876: 874: 869: 865: 861: 857: 853: 849: 845: 844:metronidazole 837: 835: 832: 830: 826: 817: 815: 811: 809: 801: 796: 792: 788: 784: 780: 777: 773: 770: 769: 768: 762: 757: 753: 749: 745: 741: 737: 734: 730: 727: 724: 720: 716: 715: 714: 708: 704: 696: 689: 687: 685: 681: 680:acne vulgaris 672: 670: 668: 661: 659: 657: 653: 648: 644: 640: 639: 634: 633: 628: 623: 621: 617: 616: 607: 603: 601: 599: 595: 591: 587: 583: 579: 575: 574:Richard Gallo 568:Cathelicidins 567: 565: 563: 559: 555: 551: 549: 545: 541: 537: 533: 529: 524: 522: 518: 514: 510: 502: 498: 493: 486: 484: 482: 474: 472: 470: 466: 462: 458: 454: 450: 442: 440: 438: 433: 431: 427: 423: 419: 415: 411: 407: 403: 394: 387: 385: 383: 379: 378: 372: 370: 366: 365:laser surgery 362: 358: 354: 350: 346: 342: 338: 334: 330: 329:metronidazole 325: 323: 322:steroid cream 319: 315: 309: 307: 303: 299: 295: 291: 287: 284: 280: 271: 267: 263: 260: 258: 254: 251: 247: 243: 239: 235: 232: 230: 226: 222: 220: 216: 212: 210: 206: 202: 198: 195: 191: 187: 183: 179: 175: 171: 168: 165: 163: 162:Complications 159: 156: 152: 148: 144: 142: 138: 135: 132: 130: 126: 117: 79: 78: 76: 74:Pronunciation 72: 67: 63: 58: 54: 50: 45: 37: 33: 28: 24: 19: 5499:Hypohidrosis 5492:Palmoplantar 5360:Trichomegaly 5263:Kinking hair 5180:Hidradenitis 5156:Folliculitis 5148:Inflammation 5037: 4940: 4854:Halogen acne 4848:steroid acne 4694: 4641: 4558: 4482:Racquet nail 4452:Pincer nails 4427:Onychophosis 4387:Melanonychia 4357:Ingrown nail 4347:Hapalonychia 4322:Chevron nail 4292:Ingrown nail 4284:Onychophagia 4258:Azure lunula 4243:Beau's lines 4091:Ingrown nail 3663:Dermatophyte 3658:Gonococcemia 3643:Folliculitis 3637: 3284:Neurofibroma 3252:subcutaneous 3052: 3041: 3017: 3006: 2991: 2976: 2918: 2914: 2904: 2871: 2867: 2861: 2842: 2838: 2828: 2798:(1): 84–88. 2795: 2791: 2785: 2776:the original 2771: 2762: 2737: 2733: 2727: 2690: 2687:SpringerPlus 2686: 2676: 2641: 2637: 2627: 2594: 2590: 2584: 2549: 2545: 2493: 2489: 2454:. Retrieved 2450:the original 2444: 2437: 2402: 2398: 2388: 2353: 2349: 2339: 2315:(1): 38–45. 2312: 2308: 2258: 2254: 2207:(1): 65–79. 2204: 2200: 2190: 2174: 2135: 2131: 2079: 2075: 2033: 2029: 2023: 2011:. Retrieved 2007:the original 1997: 1981: 1976: 1965:the original 1944: 1940: 1927: 1902:11424/241569 1882: 1878: 1868: 1836:(1): 21–25. 1833: 1829: 1819: 1786: 1780: 1737: 1733: 1723: 1690: 1684: 1662:. Retrieved 1644: 1619: 1615: 1578: 1551: 1501: 1497: 1459:the original 1438: 1434: 1420: 1396: 1389: 1365: 1358: 1323: 1319: 1309: 1296: 1292: 1283: 1250: 1246: 1225:. Retrieved 1216: 1162:(1): 35–46. 1159: 1155: 1081: 1077: 1067: 1017: 1014:Epidemiology 1008: 1000: 991: 987: 983:fusidic acid 976: 964: 953: 907: 900: 896: 892: 888: 880:tetracycline 877: 868:tetracycline 864:isotretinoin 852:azelaic acid 841: 833: 821: 812: 805: 790: 766: 758:is affected. 712: 676: 665: 656:B. oleronius 655: 647:B. oleronius 646: 642: 636: 630: 624: 613: 611: 605: 578:cathelicidin 571: 552: 540:isotretinoin 525: 505: 500: 496: 478: 446: 434: 399: 375: 373: 361:Dermabrasion 357:isotretinoin 345:azithromycin 341:tetracycline 326: 310: 278: 277: 209:Risk factors 55:Acne rosacea 27: 18: 5482:Generalized 5293:Monilethrix 5094:Follicular 4976:Gnathophyma 4916:Pomade acne 4771:Prepubertal 4754:generalised 4750:Congenital 4739:generalised 4580:universalis 4487:Red lunulae 4447:Platonychia 4407:Onycholysis 4382:Mees' lines 4332:Green nails 4303:ungrouped: 4266:Koilonychia 4253:Leukonychia 4228:thickness: 4146:Herpesvirus 4126:Leukoplakia 3951:Scleroderma 3838:Specialized 3766:Generalized 3741:involvement 3653:Candidiasis 3345:involvement 3319:Myxoid cyst 3167:Acrochordon 3043:MedlinePlus 2693:(1): 1151. 2597:(2): 81–8. 1652:. DermNet, 978:Cyclosporin 873:teratogenic 860:doxycycline 856:brimonidine 838:Medications 598:Antibiotics 521:spicy foods 437:ultraviolet 355:cream, and 349:brimonidine 337:minocycline 333:doxycycline 262:Antibiotics 173:Usual onset 134:Dermatology 52:Other names 5571:Categories 5504:Anhidrosis 5324:Pili torti 5243:Hair casts 4966:Rhinophyma 4864:Bromoderma 4695:ungrouped: 4305:Paronychia 4277:behavior: 4235:Onychauxis 4086:Paronychia 3927:Vasculitis 3851:Multiforme 3849:Erythema ( 3804:Cellulitis 3755:Blanchable 3504:Blistering 3494:Ichthyosis 3352:Eczematous 3264:Hemangioma 3019:DiseasesDB 2013:30 January 1740:(1): 3–6. 1664:3 February 1059:References 922:carvedilol 918:propanolol 848:ivermectin 733:rhinophyma 707:Micrograph 517:histamines 455:, such as 382:Theocritus 353:ivermectin 306:rhinophyma 257:Medication 167:Rhinophyma 5582:Erythemas 5544:Sebaceous 5524:Body odor 5487:Gustatory 5206:Ungrouped 5131:multiplex 5059:Ungrouped 4981:Metophyma 4926:Blackhead 4869:Chloracne 4859:Iododerma 4786:Acneiform 4759:localised 4744:patterned 4734:localised 4730:Acquired 4726:Hirsutism 4546:Hair loss 4352:Hook nail 4297:Anonychia 4081:Psoriasis 3989:disorders 3944:Indurated 3845:Urticaria 3797:Localized 3739:epidermal 3522:Varicella 3432:Psoriasis 3343:epidermal 3309:Leiomyoma 3211:Pigmented 3144:Epidermal 3054:eMedicine 2772:drugs.com 2668:209433363 2456:27 August 2411:1941-2789 2362:1942-2962 1911:0004-2749 1650:"Rosacea" 937:clonidine 825:sunscreen 802:Treatment 752:Keratitis 673:Diagnosis 572:In 2007, 548:tretinoin 481:edematous 369:sunscreen 314:menopause 283:long-term 269:Frequency 184:Long term 129:Specialty 5516:Apocrine 5425:Miliaria 5340:Poliosis 5038:variants 4986:Otophyma 4881:Tar acne 4876:Oil acne 4788:eruption 4764:X-linked 4585:Ophiasis 4565:Alopecia 4551:Baldness 4342:Hangnail 4156:Syphilis 4103:membrane 3758:Erythema 3694:Vitiligo 3648:Impetigo 3625:Pustular 3590:Miliaria 3438:Corporis 3289:Xanthoma 3238:Melanoma 3218:Freckles 3085:Archived 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Index

Rosacea (disambiguation)
pityriasis rosea
roseola

/rˈzʃ(i)ə/
Specialty
Dermatology
Symptoms
redness
swelling
small and superficial dilated blood vessels
Complications
Rhinophyma
ocular
Risk factors
Diagnostic method
Differential diagnosis
Acne
perioral dermatitis
seborrhoeic dermatitis
dermatomyositis
lupus
Medication
Antibiotics
long-term
skin condition
redness
pimples
swelling
small and superficial dilated blood vessels

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