Knowledge (XXG)

Thrombosis

Source 📝

1759:
than three hours of ischemia followed by one hour of reperfusion. In ST-elevation myocardial infarction (STEMI), IRI contributes up to 50% of final infarct size despite timely primary percutaneous coronary intervention. This is a key reason for the continued high mortality and morbidity in these conditions, despite endovascular reperfusion treatments and continuous efforts to improve timeliness and access to these treatments. Hence, protective therapies are required to attenuate IRI alongside reperfusion in acute ischemic conditions to improve clinical outcomes. Therapeutic strategies that have potential to improve clinical outcomes in reperfused STEMI patients include
1461:), by external compression on a blood vessel when a solid tumor is present, or (more rarely) extension into the vasculature (for example, renal cell cancers extending into the renal veins). Also, treatments for cancer (radiation, chemotherapy) often cause additional hypercoagulability. There are scores that correlate different aspects of patient data (comorbidities, vital signs, and others) to risk of thrombosis, such as the POMPE-C, which stratifies risk of mortality due to pulmonary embolism in patients with cancer, who typically have higher rates of thrombosis. Also, there are several predictive scores for thromboembolic events, such as Padua, Khorana, and 1421: 41: 3771:
Vries J, de Kort PL, van Rooij WJ, van den Berg JS, van Hasselt BA, Aerden LA, Dallinga RJ, Visser MC, Bot JC, Vroomen PC, Eshghi O, Schreuder TH, Heijboer RJ, Keizer K, Tielbeek AV, den Hertog HM, Gerrits DG, van den Berg-Vos RM, Karas GB, Steyerberg EW, Flach HZ, Marquering HA, Sprengers ME, Jenniskens SF, Beenen LF, van den Berg R, Koudstaal PJ, van Zwam WH, Roos YB, van der Lugt A, van Oostenbrugge RJ, Majoie CB, Dippel DW, et al. (January 1, 2015).
1775:(thrombolytics and/or anticoagulants), and surgery. The evidence supporting these treatment approaches is weak. For anticoagulant treatment, it is not clear if unfractionated and/or low molecular weight heparin treatment is effective at decreasing mortality and serious adverse events in this population. There is also insufficient evidence to understand the risk of adverse effects associated with these treatment approaches in term or preterm infants. 551: 4229: 1763:(RIC), exenatide, and metoprolol. These have emerged amongst a multitude of cardioprotective interventions investigated with largely neutral clinical data. Of these, RIC has the most robust clinical evidence, especially in the context of STEMI, but also emerging for other indications such as acute ischemic stroke and aneurysmal subarachnoid hemorrhage. 1340:. Generally speaking the risk for thrombosis increases over the life course of individuals, depending on life style factors like smoking, diet, and physical activity, the presence of other diseases like cancer or autoimmune disease, while also platelet properties change in aging individuals which is an important consideration as well. 1580:) in the area past the occlusion. Venous thrombosis can lead to pulmonary embolism when the migrated embolus becomes lodged in the lung. In people with a "shunt" (a connection between the pulmonary and systemic circulation), either in the heart or in the lung, a venous clot can also end up in the arteries and cause arterial embolism. 1609:
following surgery is common if there are no issues with bleeding. Generally, a risk-benefit analysis is required, as all anticoagulants lead to an increased risk of bleeding. In people admitted to hospital, thrombosis is a major cause for complications and occasionally death. In the UK, for instance,
3770:
Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, Schonewille WJ, Vos JA, Nederkoorn PJ, Wermer MJ, van Walderveen MA, Staals J, Hofmeijer J, van Oostayen JA, Lycklama Ă  Nijeholt GJ, Boiten J, Brouwer PA, Emmer BJ, de Bruijn SF, van Dijk LC, Kappelle LJ, Lo RH, van Dijk EJ, de
1758:
With reperfusion comes ischemia/reperfusion (IR) injury (IRI), which paradoxically causes cell death in reperfused tissue and contributes significantly to post-reperfusion mortality and morbidity. For example, in a feline model of intestinal ischemia, four hours of ischemia resulted in less injury
1405:
Endothelial injury is almost invariably involved in the formation of thrombi in arteries, as high rates of blood flow normally hinder clot formation. In addition, arterial and cardiac clots are normally rich in platelets–which are required for clot formation in areas under high stress due to blood
1424:
Cancer-associated thrombosis can result from: (1) stasis, i.e., direct pressure on blood vessels by the tumor mass, poor performance status, and bed rest following surgical procedures; (2) iatrogenic, due to treatment with antineoplastic medications; and (3) secretion of heparanase from malignant
1680:
of blood is monitored. Self-monitoring and self-management are safe options for competent patients, though their practice varies. In Germany, about 20% of patients were self-managed while only 1% of U.S. patients did home self-testing (according to one 2012 study). Other medications such as
2818:
Ho AF, Zheng H, De Silva DA, Wah W, Earnest A, Pang YH, Xie Z, Pek PP, Liu N (November 2018). "The Relationship Between Ambient Air Pollution and Acute Ischemic Stroke: A Time-Stratified Case-Crossover Study in a City-State With Seasonal Exposure to the Southeast Asian Haze Problem".
2927:
Ho AF, Wah W, Earnest A, Ng YY, Xie Z, Shahidah N, Yap S, Pek PP, Liu N (November 15, 2018). "Health impacts of the Southeast Asian haze problem – A time-stratified case crossover study of the relationship between ambient air pollution and sudden cardiac deaths in Singapore".
3712:
Tran HA, Gibbs H, Merriman E, Curnow JL, Young L, Bennett A, Tan C, Chunilal SD, Ward CM, Baker R, Nandurkar H (March 2019). "New guidelines from the Thrombosis and Haemostasis Society of Australia and New Zealand for the diagnosis and management of venous
1541:
may or may not be ischemic, since veins distribute deoxygenated blood that is less vital for cellular metabolism. Nevertheless, non-ischemic venous thrombosis may still be problematic, due to the swelling caused by blockage to venous drainage. In
1488:
Organisation: following the thrombotic event, residual vascular thrombus will be re-organised histologically with several possible outcomes. For an occlusive thrombus (defined as thrombosis within a small vessel that leads to complete occlusion),
577:
plaques. Since blockage of the artery is gradual, the onset of symptomatic thrombotic strokes is slower. Thrombotic stroke can be divided into two categories — large vessel disease or small vessel disease. The former affects vessels such as the
4302: 4283: 1675:
that can be taken orally to reduce thromboembolic occurrence. Where a more effective response is required, heparin can be given (by injection) concomitantly. As a side effect of any anticoagulant, the risk of bleeding is increased, so the
531:
occurs when clots then migrate downstream and can affect any organ. Alternatively, arterial occlusion occurs as a consequence of embolism of blood clots originating from the heart ("cardiogenic" emboli). The most common cause is
1708:, which enhances the normal destruction of blood clots by the body's enzymes. This carries an increased risk of bleeding so is generally only used for specific situations (such as severe stroke or a massive pulmonary embolism). 137:
to prevent blood loss. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an
3231:
van der Hulle T, den Exter PL, Kooiman J, van der Hoeven JJ, Huisman MV, Klok FA (2014). "Meta-analysis of the efficacy and safety of new oral anticoagulants in patients with cancer-associated acute venous thromboembolism".
165:) leads to a blood clot in the affected part of the body, while arterial thrombosis (and, rarely, severe venous thrombosis) affects the blood supply and leads to damage of the tissue supplied by that artery ( 2872:"Time-Stratified Case Crossover Study of the Association of Outdoor Ambient Air Pollution With the Risk of Acute Myocardial Infarction in the Context of Seasonal Exposure to the Southeast Asian Haze Problem" 1505:. For a mural thrombus (defined as a thrombus in a large vessel that restricts the blood flow but does not occlude completely), histological reorganisation of the thrombus does not occur via the classic 1528:
Ischemia/infarction: if an arterial thrombus cannot be lysed by the body and it does not embolise, and if the thrombus is large enough to impair or occlude blood flow in the involved artery, then local
3772: 3615:
Dentali F, Douketis JD, Gianni M, Lim W, Crowther MA (February 2007). "Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients".
4251: 5154: 695:
Some risk factors predispose for venous thrombosis while others increase the risk of arterial thrombosis. Newborn babies in the neonatal period are also at risk of a thromboembolism.
3550: 3488: 608:
by a thrombus. This restriction gives an insufficient supply of oxygen to the heart muscle which then results in tissue death (infarction). A lesion is then formed which is the
197:
Thrombosis is generally defined by the type of blood vessel affected (arterial or venous thrombosis) and the precise location of the blood vessel or the organ supplied by it.
2212: 438:
thrombosis is a condition that may occur due to infection, intravenous drug use or malignancy. Jugular vein thrombosis can have a varying list of complications, including:
536:, which causes a blood stasis within the atria with easy thrombus formation, but blood clots can develop inside the heart for other reasons too as infective endocarditis. 284:) by a thrombus. The condition usually comes to light after vigorous exercise and usually presents in younger, otherwise healthy people. Men are affected more than women. 2106: 1634:(LMWH) administration, mechanical calf compression or (if all else is contraindicated and the patient has recently developed deep vein thrombosis) the insertion of a 3953:
Bai J, Lyden PD (January 19, 2015). "Revisiting Cerebral Postischemic Reperfusion Injury: New Insights in Understanding Reperfusion Failure, Hemorrhage, and Edema".
3082: 5147: 1771:
Treatment options for full-term and preterm babies who develop thromboembolism include expectant management (with careful observation), nitroglycerin ointment,
411:
by a thrombus. Symptoms may include headache, abnormal vision, any of the symptoms of stroke such as weakness of the face and limbs on one side of the body and
4368: 4941: 612:. MI can quickly become fatal if emergency medical treatment is not received promptly. If diagnosed within 12 hours of the initial episode (attack) then 1650:
The treatment for thrombosis depends on whether it is in a vein or an artery, the impact on the person, and the risk of complications from treatment.
5140: 4008: 3432:
Antic D, Milic N, Nikolovski S, Todorovic M, Bila J, Djurdjevic P, Andjelic B, Djurasinovic V, Sretenovic A, Vukovic V, Jelicic J (July 22, 2016).
495:
infections of the face, for example nasal or upper lip pustules may thus spread directly into the cavernous sinus, causing stroke-like symptoms of
1879:
Min SK, Kim YH, Joh JH, Kang JM, Park UJ, Kim HK, Chang JH, Park SJ, Kim JY, Bae JI, Choi SY, Kim CW, Park SI, Yim NY, Jeon YS (September 2016).
1457:
may cause increased risk of thrombosis by possible activation of the coagulation system by cancer cells or secretion of procoagulant substances (
604:
Myocardial infarction (MI), or heart attack, is caused by ischemia (restriction in the blood supply), which is often due to the obstruction of a
3277:"A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score" 5271: 1997: 1789: 1639: 1583:
Arterial embolism can lead to obstruction of blood flow through the blood vessel that is obstructed by it, and a lack of oxygen and nutrients (
3129:
Ito T, Kakihana Y, Maruyama I (January 1, 2016). "Thrombomodulin as an intravascular safeguard against inflammatory and thrombotic diseases".
4713: 4211: 4192: 4173: 4154: 4135: 3113: 2804: 2720: 2694: 2628: 2606: 2570: 2468: 2449: 2427: 1863: 4256: 1521:
cells to cover the clot, and this layer of mural smooth muscle will be vascularised by the blood inside the vessel lumen rather than by the
4718: 2231: 1366:. Recent studies indicate that white blood cells play a pivotal role in deep vein thrombosis, mediating numerous pro-thrombotic actions. 5446: 5429: 1642:
has issued guidance to the effect that preventative measures should be used in medical patients, in anticipation of formal guidelines.
1420: 3573: 1614:
heard in 2005 that the annual rate of death due to thrombosis was 25,000, with at least 50% of these being hospital-acquired. Hence
450:. Though characterized by a sharp pain at the site of the vein, it can prove difficult to diagnose, because it can occur at random. 1576:, finally lodging in and completely obstructing a blood vessel, which unless treated very quickly will lead to tissue necrosis (an 5508: 5460: 4868: 4485: 2255:
Mendelson SJ, Prabhakaran S (March 16, 2021). "Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke".
1433:
which may occur in heart failure, or after long periods of sedentary behaviour, such as sitting on a long airplane flight. Also,
398: 1638:. In patients with medical rather than surgical illness, LMWH too is known to prevent thrombosis, and in the United Kingdom the 4500: 4361: 3275:
BARBAR S, NOVENTA F, ROSSETTO V, FERRARI A, BRANDOLIN B, PERLATI M, DE BON E, TORMENE D, PAGNAN A, PRANDONI P (November 2010).
1936:
Hughes ES (February 1, 1949). "Venous obstruction in the upper extremity; Paget-Schroetter's syndrome; a review of 320 cases".
1391: 5227: 4819: 2346:"Early Hepatic Artery Thrombosis after Liver Transplantation: A Systematic Review of the Incidence, Outcome and Risk Factors" 1677: 1510: 558:
A stroke is the rapid decline of brain function due to a disturbance in the supply of blood to the brain. This can be due to
5514: 1398:, which is a key modulator of thrombin activity. The result is a sustained activation of thrombin and reduced production of 5500: 4631: 3079: 5488: 5451: 4856: 2186: 269: 5321: 4936: 4561: 1760: 1705: 1631: 51:
of the lower right extremity, resulting from acute arterial thrombosis of the right leg (on the left side of the image)
5641: 5217: 4951: 4946: 4673: 4663: 1627: 1164: 891: 4065:
Hausenloy DJ, Botker HE, Engstrom T, Erlinge D, Heusch G, Ibanez B, Kloner RA, Ovize M, Yellon DM (April 26, 2016).
5596: 5441: 5052: 4703: 4678: 4495: 4424: 4354: 4067:"Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations" 3669: 1799: 1216: 464: 459: 420: 1854:
Handin RI (2005). "Chapter 53: bleeding and thrombosis". In Kasper DL, Braunwald E, Fauci AS, et al. (eds.).
5712: 5283: 5264: 5077: 5020: 4668: 4621: 4471: 4434: 1794: 1682: 1635: 1073: 636: 4829: 4824: 298: 5682: 5425: 5254: 5062: 4875: 4648: 4626: 4329: 979: 484: 480: 476: 264: 5465: 3574:"Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy" 3434:"Development and validation of multivariable predictive model for thromboembolic events in lymphoma patients" 5672: 5117: 5099: 4581: 4576: 4540: 4510: 1772: 1611: 1458: 954: 189:. An arterial embolus may travel further down the affected blood vessel, where it can lodge as an embolism. 5586: 5561: 5519: 5089: 5072: 5067: 5057: 4898: 4834: 4476: 4377: 3624: 2043: 2009: 1971: 1591:. This can affect any organ; for instance, arterial embolism of the brain is one of the causes of stroke. 1547: 334: 91: 40: 4233: 3670:"Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data" 5581: 5571: 5389: 5094: 4839: 4698: 4690: 4658: 4545: 2100: 1668: 1619: 1600: 1438: 640: 599: 488: 376: 185:. Complications can arise when a venous thromboembolism (commonly called a VTE) lodges in the lung as a 5337: 5232: 5222: 5008: 5003: 4807: 4599: 1784: 1543: 1383: 1127: 483:
ophthalmic veins of the orbit, which drain directly posteriorly into the cavernous sinus through the
408: 293: 217: 162: 22: 3629: 2014: 5769: 5576: 5566: 5362: 5242: 5084: 4851: 4306: 1717: 1686: 1434: 1098: 815: 804: 625: 533: 471:
of the basal skull dura, due to the retrograde spread of infection and endothelial damage from the
416: 340: 158: 4009:"Remote Ischemic Conditioning in Emergency Medicine—Clinical Frontiers and Research Opportunities" 5702: 5384: 5189: 4998: 4908: 4490: 4047: 3986: 3889: 3810: 3752: 3650: 3471: 3257: 3162: 2961: 2852: 2781: 2288: 2035: 1753: 1623: 1497:
tissue, where the scar tissue will either permanently obstruct the vessel, or contract down with
1363: 1000: 934: 879: 688: 443: 364: 306: 252: 186: 114: 76: 5342: 5316: 3601: 2870:
Ho AF, Zheng H, Earnest A, Cheong KH, Pek PP, Seok JY, Liu N, Kwan YH, Tan JW (March 19, 2019).
1618:(prevention of thrombosis) is increasingly emphasized. In patients admitted for surgery, graded 1325: 1319: 670:" has been suggested to describe the three factors necessary for the formation of thrombosis: 667: 2228: 5591: 5367: 5276: 4789: 4738: 4638: 4207: 4188: 4169: 4150: 4131: 4104: 4086: 4039: 4031: 3978: 3970: 3935: 3927: 3881: 3873: 3802: 3744: 3694: 3642: 3593: 3533: 3463: 3455: 3414: 3396: 3355: 3347: 3306: 3298: 3249: 3213: 3154: 3146: 3109: 3053: 3012: 2953: 2945: 2909: 2891: 2844: 2836: 2773: 2734: 2528: 2510: 2367: 2323: 2280: 2272: 2168: 2088: 2027: 1953: 1945: 1918: 1900: 1859: 1836: 1737: 1701: 1538: 1064: 528: 206: 150: 65: 56: 1881:"Diagnosis and Treatment of Lower Extremity Deep Vein Thrombosis: Korean Practice Guidelines" 1429:
Causes of disturbed blood flow include stagnation of blood flow past the point of injury, or
5417: 5357: 5352: 5212: 4794: 4443: 4094: 4078: 4023: 3962: 3919: 3865: 3792: 3784: 3734: 3726: 3684: 3638: 3634: 3585: 3523: 3445: 3404: 3386: 3337: 3288: 3241: 3203: 3193: 3138: 3043: 3002: 2992: 2937: 2899: 2883: 2828: 2765: 2518: 2502: 2357: 2315: 2264: 2158: 2078: 2070: 2019: 1908: 1892: 1828: 1359: 1333: 1288: 724: 587: 583: 579: 467:
is a specialised form of cerebral venous sinus thrombosis, where there is thrombosis of the
61: 1728:
Mechanical clot retrieval and catheter-guided thrombolysis are used in certain situations.
1587:) of the downstream tissue. The tissue can become irreversibly damaged, a process known as 237:
Three factors are important in the formation of a blood clot within a deep vein—these are:
5697: 5531: 5237: 4986: 4981: 4893: 4616: 4571: 4451: 4246: 3907: 3714: 3086: 2235: 1998:"Review article: portal vein thrombosis â€“ new insights into aetiology and management" 1502: 1442: 1387: 1085: 965: 656: 605: 574: 472: 468: 322: 281: 182: 5372: 3494:
Clinical guideline 92: Venous thromboembolism: reducing the risk for patients in hospital
3375:"Development and validation of a predictive model for chemotherapy-associated thrombosis" 3324:
Khorana AA, Francis CW, Culakova E, Fisher RI, Kuderer NM, Lyman GH (January 20, 2006).
1390:
in endothelium producing to a pro-thrombotic state. When this occurs, endothelial cells
1374:
Any inflammatory process, such as trauma, surgery or infection, can cause damage to the
5722: 5434: 5377: 5259: 5035: 4885: 4748: 4708: 4643: 4604: 4515: 4099: 4066: 3409: 3374: 3208: 3181: 3089:
This article was last reviewed on May 23, 2007, and was last modified on March 6, 2010.
2979:
Faria AV, Andrade SS, Peppelenbosch MP, Ferreira-Halder CV, Fuhler GM (December 2020).
2904: 2871: 2523: 2490: 2163: 2146: 2083: 2058: 1913: 1880: 1551: 1395: 1195: 847: 590:. The latter can affect smaller vessels, such as the branches of the circle of Willis. 424: 360: 310: 4323: 4319: 4311: 3689: 3007: 2980: 2832: 2489:
Romantsik O, Bruschettini M, Zappettini S, Ramenghi LA, Calevo MG (November 7, 2016).
5763: 5732: 5554: 5549: 5544: 5301: 5132: 4903: 4566: 4241: 4051: 3293: 3276: 3166: 2769: 2362: 2345: 2292: 2023: 1672: 1659: 1555: 1518: 1506: 1498: 1490: 1430: 1379: 1349: 1329: 1254: 496: 492: 277: 4315: 3990: 3893: 3756: 3654: 3261: 2965: 2856: 5742: 5184: 5044: 4956: 4771: 4461: 4404: 4346: 3814: 3589: 3475: 2785: 2506: 2039: 1697: 1522: 1478: 1462: 1450: 1042: 867: 660: 652: 613: 550: 435: 352: 344: 318: 302: 231: 106: 3142: 2120: 1736:
Arterial thrombosis is platelet-rich, and inhibition of platelet aggregation with
4334: 4027: 3391: 3048: 3031: 2941: 177:, which could then travel through the circulation and lodge somewhere else as an 5539: 5347: 5179: 5168: 5109: 4505: 1375: 1144: 783: 681: 674: 651:
Thrombosis prevention is initiated with assessing the risk for its development.
447: 69: 4082: 3828: 3528: 3511: 2997: 523:(a fat-rich deposit in the blood vessel wall), and is therefore referred to as 5727: 5692: 5667: 5025: 4976: 4920: 4913: 4743: 2190: 1577: 1534: 1415: 1337: 624:
An arterial thrombus or embolus can also form in the limbs, which can lead to
567: 504: 500: 382: 273: 134: 4090: 4035: 3974: 3931: 3877: 3459: 3400: 3351: 3342: 3325: 3302: 3150: 2949: 2895: 2840: 2514: 2276: 1949: 1904: 1896: 5717: 5662: 5249: 4779: 4520: 4456: 4412: 4395: 4390: 4296: 4292: 3198: 2887: 2268: 1399: 1152: 1148: 1057: 1053: 356: 227: 126: 4108: 4043: 3982: 3939: 3869: 3806: 3748: 3698: 3646: 3597: 3537: 3467: 3418: 3359: 3310: 3253: 3217: 3158: 3057: 3016: 2957: 2913: 2848: 2777: 2532: 2371: 2327: 2284: 2172: 2092: 2031: 1957: 1922: 1840: 321:. Treatment varies between therapy and surgical intervention by the use of 4228: 3885: 3788: 2319: 2187:"eMedicine Article on Internal Jugular Vein Thrombosis by Dale K. Mueller" 1832: 173:). A piece of either an arterial or a venous thrombus can break off as an 5631: 5626: 5616: 5475: 5306: 5164: 4993: 4595: 4532: 4466: 4417: 4130:. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. 3923: 3773:"A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke" 3373:
Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW (May 15, 2008).
1664: 1588: 1584: 1573: 1530: 1514: 1454: 1382:
to the blood coagulation system. Inflammatory and other stimuli (such as
1140: 1118: 968: 559: 520: 412: 178: 170: 166: 102: 48: 3739: 3555: 3512:"Awareness and politics of venous thromboembolism in the United kingdom" 3493: 2306:
Creager MA, Kaufman JA, Conte MS (June 7, 2012). "Acute Limb Ischemia".
1622:
are widely used, and in severe illness, prolonged immobility and in all
5677: 5636: 3797: 3730: 1741: 1606: 1567: 1482: 1446: 826: 609: 563: 314: 174: 139: 4275: 3966: 3910:, Hausenloy DJ (September 13, 2007). "Myocardial Reperfusion Injury". 3450: 3433: 3245: 2074: 1402:
and tissue factor inhibitor, which furthers the pro-thrombotic state.
5621: 4386: 4287: 4260: 1031: 1020: 913: 545: 516: 439: 404: 386: 154: 130: 122: 1700:
is the pharmacological destruction of blood clots by administering
573:
In thrombotic stroke, a thrombus (blood clot) usually forms around
4730: 1419: 1112: 549: 348: 110: 1481:
is the physiological breakdown of blood clots by enzymes such as
4762: 1494: 223: 146: 118: 5136: 4350: 475:
of the face. The facial veins in this area anastomose with the
385:
by a thrombus. This tends to lead to reduced drainage from the
351:. It usually happens in the setting of another disease such as 2147:"Causes and predictors of death in cerebral venous thrombosis" 1819:
Furie B, Furie BC (2008). "Mechanisms of thrombus formation".
4128:
Brunner & Suddarth's textbook of medical-surgical nursing
3326:"Thromboembolism in Hospitalized Neutropenic Cancer Patients" 515:
Arterial thrombosis is the formation of a thrombus within an
423:. The majority of persons affected make a full recovery. The 3572:
Geerts WH, Pineo GF, Heit JA, et al. (September 2004).
2145:
CanhĂŁo P, Ferro JM, Lindgren AG, et al. (August 2005).
3182:"Potential Mechanisms of Cancer-Related Hypercoagulability" 1572:
A thrombus may become detached and enter circulation as an
655:
of developing thrombosis and its possible development into
1558:
impairment, which if severe enough can lead to blindness.
403:
Cerebral venous sinus thrombosis (CVST) is a rare form of
2121:"Renal vein thrombosis: MedlinePlus Medical Encyclopedia" 1425:
tumors that results in degradation of endogenous heparin.
3556:
Clinical guideline 46: Venous thromboembolism (surgical)
2756:
Vaughan DE (August 2005). "PAI-1 and atherothrombosis".
1493:
will reorganise the occlusive thrombus into collagenous
1378:
of the vessel's wall. The main mechanism is exposure of
519:. In most cases, arterial thrombosis follows rupture of 272:
or upper extremity DVT (UEDVT) is the obstruction of an
2596: 2594: 2592: 2590: 2588: 2586: 2584: 2582: 2580: 2439: 2437: 222:
Deep vein thrombosis (DVT) is the formation of a blood
2710: 2708: 2706: 2704: 2684: 2682: 2680: 2678: 2676: 2674: 2672: 2670: 2668: 2666: 2664: 2662: 2660: 2658: 2560: 2558: 2556: 2554: 2552: 2550: 2548: 2546: 2544: 2542: 2417: 2415: 2413: 2411: 2409: 2407: 2405: 2403: 2401: 903:
Ovarian hyper-stimulation therapy to treat infertility
3856:
Grace PA (May 1994). "Ischaemia-reperfusion injury".
3551:
National Institute for Health and Clinical Excellence
3489:
National Institute for Health and Clinical Excellence
2656: 2654: 2652: 2650: 2648: 2646: 2644: 2642: 2640: 2638: 2491:"Heparin for the treatment of thrombosis in neonates" 2399: 2397: 2395: 2393: 2391: 2389: 2387: 2385: 2383: 2381: 1996:
Webster GJ, Burroughs AK, Riordan SM (January 2005).
1716:
Arterial thrombosis may require surgery if it causes
4265: 2981:"Platelets in aging and cancer-"double-edged sword"" 1437:, causes stagnant blood in the left atrium (LA), or 5652: 5609: 5530: 5474: 5416: 5409: 5402: 5330: 5292: 5205: 5198: 5108: 5043: 5034: 4969: 4929: 4884: 4788: 4770: 4761: 4729: 4689: 4594: 4554: 4531: 4442: 4433: 4403: 4385: 4269: 639:usually occurs as a devastating complication after 75: 55: 33: 2229:MDGuidelines > Arterial Embolism And Thrombosis 1744:may reduce the risk of recurrence or progression. 1546:this manifests as pain, redness, and swelling; in 230:. It most commonly affects leg veins, such as the 4007:Ho AF, Jun C, Ong ME, Hausenloy DJ (April 2019). 3075: 3073: 3071: 3069: 3067: 1689:are increasingly being used instead of warfarin. 16:Formation of blood clots inside the blood vessels 3851: 3849: 2618: 2616: 2242:by Presley Reed, MD. Retrieved on April 30, 2010 381:Renal vein thrombosis is the obstruction of the 3106:Robbins and Cotran Pathologic Basis of Disease 5148: 4362: 3080:labtestsonline > Hypercoagulable Disorders 8: 4187:. Chichester, West Sussex: Wiley-Blackwell. 3108:. Philadelphia: Elsevier. pp. 122–130. 2344:Bekker J, Ploem S, de Jong KP (April 2009). 2105:: CS1 maint: multiple names: authors list ( 659:. Some of these risk factors are related to 161:). Venous thrombosis (sometimes called DVT, 2495:The Cochrane Database of Systematic Reviews 2057:DeLeve LD, Valla DC, Garcia-Tsao G (2009). 1324:The main causes of thrombosis are given in 1265:Post-menopausal hormone replacement therapy 5413: 5406: 5202: 5155: 5141: 5133: 5040: 4942:Chronic cerebrospinal venous insufficiency 4767: 4439: 4400: 4369: 4355: 4347: 4266: 3180:Nasser NJ, Fox J, Agbarya A (March 2020). 2002:Alimentary Pharmacology & Therapeutics 1856:Harrison's Principles of Internal Medicine 697: 503:, as well as spread of infection to cause 39: 30: 4098: 3796: 3738: 3688: 3628: 3527: 3449: 3408: 3390: 3341: 3292: 3207: 3197: 3047: 3006: 2996: 2903: 2876:Journal of the American Heart Association 2522: 2361: 2162: 2082: 2013: 1912: 554:Acute thrombus in the right MCA M1 branch 347:and reduction of the blood supply to the 255:, pain and redness of the affected area. 4250:) is being considered for deletion. See 2605:sfn error: no target: CITEREFMoliterno ( 2448:sfn error: no target: CITEREFMoliterno ( 1858:(16th ed.). New York: McGraw-Hill. 1706:recombinant tissue plasminogen activator 309:. This form of thrombosis presents with 101: 'clotting') is the formation of a 4002: 4000: 3639:10.7326/0003-4819-146-4-200702200-00007 3567: 3565: 3505: 3503: 2719:sfn error: no target: CITEREFCopstead ( 2569:sfn error: no target: CITEREFCopstead ( 2213:"Guidelines Cavernous sinus thrombosis" 1811: 415:. The diagnosis is usually made with a 407:which results from the blockage of the 3032:"The role of leukocytes in thrombosis" 2803:sfn error: no target: CITEREFBrunner ( 2693:sfn error: no target: CITEREFBrunner ( 2467:sfn error: no target: CITEREFBrunner ( 2426:sfn error: no target: CITEREFHoffman ( 2250: 2248: 2098: 1790:Disseminated intravascular coagulation 1300:thought to be related to inflammation 1186:Selective estrogen-receptor modulators 181:. This type of embolism is known as a 4714:Hereditary hemorrhagic telangiectasia 3829:"Aspirin Monograph for Professionals" 3668:Heneghan C, Ward A, Perera R (2012). 3281:Journal of Thrombosis and Haemostasis 3131:Expert Opinion on Therapeutic Targets 3099: 3097: 3095: 3030:Swystun LL, Liaw PC (June 27, 2016). 2758:Journal of Thrombosis and Haemostasis 2600: 2484: 2482: 2480: 2478: 2443: 1748:Targeting ischemia/reperfusion injury 945:Local vein damage, incompetent valves 738:slow flow is modifiable with exercise 7: 4719:Generalized essential telangiectasia 2714: 2627:sfn error: no target: CITEREFAbele ( 2564: 1938:Surgery, Gynecology & Obstetrics 1245:Paroxysmal nocturnal hemoglobinnuria 1117:inhibits physiological breakdown of 838:Pregnancy and the post-partum period 2930:International Journal of Cardiology 2798: 2688: 2462: 2421: 2350:American Journal of Transplantation 339:Portal vein thrombosis affects the 4185:Therapeutic advances in thrombosis 2164:10.1161/01.STR.0000173152.84438.1c 1074:Antiphospholipid antibody syndrome 14: 4254:to help reach a consensus. â€ş 4168:. New York: McGraw-Hill Medical. 2833:10.1016/j.annemergmed.2018.06.037 2622: 2059:"Vascular disorders of the liver" 1885:Vascular Specialist International 5509:platelet storage pool deficiency 5461:Heparin-induced thrombocytopenia 4869:Cerebral venous sinus thrombosis 4227: 3719:The Medical Journal of Australia 3516:Arterioscler. Thromb. Vasc. Biol 3294:10.1111/j.1538-7836.2010.04044.x 2770:10.1111/j.1538-7836.2005.01420.x 2363:10.1111/j.1600-6143.2008.02541.x 2024:10.1111/j.1365-2036.2004.02301.x 399:Cerebral venous sinus thrombosis 393:Cerebral venous sinus thrombosis 3955:International Journal of Stroke 3912:New England Journal of Medicine 3777:New England Journal of Medicine 2308:New England Journal of Medicine 1821:New England Journal of Medicine 916:by abnormality, tumor, hematoma 715:Previous episodes of thrombosis 251:Classical signs of DVT include 5228:Activated protein C resistance 4820:Hepatic veno-occlusive disease 3858:The British Journal of Surgery 3590:10.1378/chest.126.3_suppl.338S 3438:American Journal of Hematology 2507:10.1002/14651858.CD012185.pub2 2240:The Medical Disability Advisor 1678:international normalized ratio 1511:platelet-derived growth factor 653:Some people have a higher risk 305:or of the hepatic part of the 244:the thickness of the blood and 1: 4632:Aneurysm of sinus of Valsalva 4486:Monckeberg's arteriosclerosis 3690:10.1016/S0140-6736(11)61294-4 3143:10.1517/14728222.2016.1086750 2985:Cancer and Metastasis Reviews 1358:, is caused by, for example, 1287:when a thrombus forms, it is 1284:Venous inflammation/phlebitis 677:(blood stasis or turbulence), 247:qualities of the vessel wall. 5322:Trousseau sign of malignancy 4937:Chronic venous insufficiency 4562:Aortoiliac occlusive disease 4204:Atlas of gynecologic surgery 4028:10.1097/SHK.0000000000001362 3392:10.1182/blood-2007-10-116327 3330:Journal of Clinical Oncology 3049:10.1182/blood-2016-05-718114 2942:10.1016/j.ijcard.2018.04.070 2821:Annals of Emergency Medicine 1761:remote ischemic conditioning 1632:low molecular weight heparin 1513:degranulated by the clotted 1268:discontinuation reduces risk 1236:Myeloproliferative disorders 1063:congenital; associated with 896:discontinuation reduces risk 884:discontinuation reduces risk 735:Slow or turbulent blood flow 699:Risk factors for thrombosis 125:) is injured, the body uses 5642:Nonthrombocytopenic purpura 5218:Antithrombin III deficiency 4952:Inferior vena cava syndrome 4947:Superior vena cava syndrome 4674:Vertebral artery dissection 4664:Intracranial berry aneurysm 4149:. St. Louis, Mo: Elsevier. 1165:Antithrombin III deficiency 892:Hormone replacement therapy 687:altered blood coagulation ( 343:, which can lead to portal 5786: 5597:Congenital afibrinogenemia 5501:Glanzmann's thrombasthenia 5053:Hypertensive heart disease 4704:Arteriovenous malformation 4679:Familial aortic dissection 3529:10.1161/ATVBAHA.108.162586 2998:10.1007/s10555-020-09926-2 1800:Thrombotic microangiopathy 1751: 1683:direct thrombin inhibitors 1657: 1598: 1565: 1413: 1347: 1317: 1217:Inflammatory bowel disease 597: 543: 465:Cavernous sinus thrombosis 460:Cavernous sinus thrombosis 457: 454:Cavernous sinus thrombosis 396: 374: 332: 291: 262: 215: 204: 109:, obstructing the flow of 20: 5713:Gastrointestinal bleeding 5515:Hermansky–Pudlak syndrome 5284:Antiphospholipid syndrome 5265:Essential thrombocythemia 5175: 5078:Renovascular hypertension 5021:Hepatic artery thrombosis 4669:Carotid artery dissection 4622:Abdominal aortic aneurysm 4472:Intermittent claudication 4435:Peripheral artery disease 2234:February 2, 2018, at the 1976:National Cancer Institute 1795:Hepatic artery thrombosis 1441:(LAA), and can lead to a 1386:) can lead to changes in 912:Compression of a vein or 795:Acute respiratory failure 684:) injury/dysfunction, and 637:Hepatic artery thrombosis 117:. When a blood vessel (a 47: 38: 5683:Subconjunctival bleeding 5489:Bernard–Soulier syndrome 5452:Upshaw–Schulman syndrome 5426:Thrombocytopenic purpura 5255:Sticky platelet syndrome 5063:Hypertensive nephropathy 4876:Post-thrombotic syndrome 4857:Paget–Schroetter disease 4649:Coronary artery aneurysm 4627:Thoracic aortic aneurysm 4252:templates for discussion 4083:10.1093/eurheartj/ehw145 3343:10.1200/jco.2005.03.8877 1897:10.5758/vsi.2016.32.3.77 1517:will attract a layer of 1509:mechanism. Instead, the 1501:activity to unblock the 980:Repetitive motion injury 955:Central venous catheters 485:superior orbital fissure 270:Paget-Schroetter disease 265:Paget-Schroetter disease 259:Paget-Schroetter disease 145:Thrombosis may occur in 5673:Intracranial hemorrhage 5118:Orthostatic hypotension 5100:White coat hypertension 4577:Fibromuscular dysplasia 4541:Carotid artery stenosis 3497:. London, January 2010. 3199:10.3390/cancers12030566 2888:10.1161/JAHA.118.011272 2333:(subscription required) 2269:10.1001/jama.2020.26867 1773:pharmacological therapy 1628:professional guidelines 1612:Health Select Committee 1459:paraneoplastic syndrome 1370:Endothelial cell injury 566:(a lodged particle) or 431:Jugular vein thrombosis 241:the rate of blood flow, 5587:Factor XIII deficiency 5567:Hypoprothrombinemia/II 5562:von Willebrand disease 5520:Gray platelet syndrome 5090:Pulmonary hypertension 5073:Secondary hypertension 5068:Essential hypertension 5058:Hypertensive emergency 4899:Portacaval anastomosis 4835:Portal vein thrombosis 4477:Critical limb ischemia 4378:Cardiovascular disease 4071:European Heart Journal 3870:10.1002/bjs.1800810504 3584:(3 Suppl): 338S–400S. 3510:Hunt BJ (March 2008). 3085:June 18, 2007, at the 1724:Endovascular treatment 1548:retinal vein occlusion 1426: 1354:Hypercoagulability or 1336:injury, and disturbed 1297:Ambient air pollution 1176:Falls and hip fracture 555: 335:Portal vein thrombosis 329:Portal vein thrombosis 5582:Factor XII deficiency 5572:Factor VII deficiency 5390:Renal vein thrombosis 5095:Systolic hypertension 4840:Renal vein thrombosis 4699:Arteriovenous fistula 4691:Vascular malformation 4659:Intracranial aneurysm 4546:Renal artery stenosis 4206:. Stuttgart: Thieme. 3789:10.1056/NEJMoa1411587 3559:. London, April 2007. 2737:. The Free Dictionary 2320:10.1056/NEJMcp1006054 2046:on December 10, 2012. 1833:10.1056/NEJMra0801082 1669:vitamin K antagonists 1640:Chief Medical Officer 1620:compression stockings 1601:Thrombosis prevention 1566:Further information: 1439:left atrial appendage 1423: 1414:Further information: 1207:Acute medical illness 1179:related to immobility 641:liver transplantation 600:Myocardial infarction 594:Myocardial infarction 553: 377:Renal vein thrombosis 371:Renal vein thrombosis 301:is the blockage of a 81:Dependent on location 21:For the journal, see 5338:Deep vein thrombosis 5233:Protein S deficiency 5223:Protein C deficiency 5009:Paradoxical embolism 5004:Cholesterol embolism 4830:May–Thurner syndrome 4825:Budd–Chiari syndrome 4808:Deep vein thrombosis 4803:primarily lower limb 4582:Raynaud's phenomenon 4236:at Wikimedia Commons 4183:Moliterno D (2013). 3924:10.1056/nejmra071667 3604:on October 11, 2004. 1785:Blood clotting tests 1687:direct Xa inhibitors 1544:deep vein thrombosis 1410:Disturbed blood flow 1384:hypercholesterolemia 1364:autoimmune disorders 1360:genetic deficiencies 1128:Hyperhomocysteinemia 763:Sedentary life style 614:thrombolytic therapy 409:dural venous sinuses 299:Budd-Chiari syndrome 294:Budd-Chiari syndrome 288:Budd-Chiari syndrome 218:Deep vein thrombosis 212:Deep vein thrombosis 163:deep vein thrombosis 23:Thrombosis (journal) 5577:Factor X deficiency 5466:May–Hegglin anomaly 5243:Prothrombin G20210A 5085:Benign hypertension 4166:Williams gynecology 4145:Copstead L (2013). 1767:Neonatal thrombosis 1732:Antiplatelet agents 1718:acute limb ischemia 1550:this may result in 1435:atrial fibrillation 1394:substances such as 1275:Right heart failure 1198:-stimulating agents 1169:altered coagulation 1157:altered coagulation 1132:altered coagulation 1104:altered coagulation 1099:Prothrombin G20210A 1091:altered coagulation 1078:altered coagulation 700: 675:hemodynamic changes 626:acute limb ischemia 534:atrial fibrillation 511:Arterial thrombosis 341:hepatic portal vein 159:arterial thrombosis 129:(thrombocytes) and 5703:Pulmonary hematoma 5610:Signs and symptoms 5385:Pulmonary embolism 5190:Bleeding diathesis 4999:Pulmonary embolism 4909:Esophageal varices 4847:upper limb / torso 4491:Arteriolosclerosis 4164:Hoffman B (2012). 4126:Brunner L (2010). 3731:10.5694/mja2.50004 1754:Reperfusion injury 1738:antiplatelet drugs 1702:thrombolytic drugs 1624:orthopedic surgery 1616:thromboprophylaxis 1610:the Parliamentary 1427: 1376:endothelial lining 1344:Hypercoagulability 1227:Nephrotic syndrome 1001:Spinal cord injury 880:oral contraceptive 698: 689:hypercoagulability 556: 444:pulmonary embolism 365:cholangiocarcinoma 307:inferior vena cava 276:vein (such as the 193:Signs and symptoms 187:pulmonary embolism 115:circulatory system 5757: 5756: 5753: 5752: 5605: 5604: 5592:Dysfibrinogenemia 5476:Platelet function 5398: 5397: 5277:Purpura fulminans 5130: 5129: 5126: 5125: 4970:Arteries or veins 4965: 4964: 4790:Venous thrombosis 4757: 4756: 4739:Cherry hemangioma 4639:Aortic dissection 4590: 4589: 4425:Buerger's disease 4344: 4343: 4232:Media related to 4213:978-3-13-650704-9 4194:978-1-4051-9625-3 4175:978-0-07-171672-7 4156:978-1-4557-2650-9 4137:978-0-7817-8590-7 3967:10.1111/ijs.12434 3918:(11): 1121–1135. 3683:(9813): 322–334. 3451:10.1002/ajh.24466 3444:(10): 1014–1019. 3385:(10): 4902–4907. 3287:(11): 2450–2457. 3246:10.1111/jth.12605 3115:978-1-4557-2613-4 2314:(23): 2198–2206. 2263:(11): 1088–1098. 2193:on April 14, 2021 2075:10.1002/hep.22772 1865:978-0-07-139140-5 1306: 1305: 1065:Warfarin necrosis 580:internal carotids 529:Arterial embolism 207:Venous thrombosis 201:Venous thrombosis 151:venous thrombosis 85: 84: 66:internal medicine 28:Medical condition 5777: 5418:Thrombocytopenia 5414: 5407: 5363:Lowenberg's sign 5213:Clotting factors 5203: 5157: 5150: 5143: 5134: 5041: 4852:Mondor's disease 4795:Thrombophlebitis 4768: 4444:Arteriosclerosis 4440: 4401: 4371: 4364: 4357: 4348: 4267: 4231: 4217: 4202:Abele H (2014). 4198: 4179: 4160: 4141: 4113: 4112: 4102: 4062: 4056: 4055: 4013: 4004: 3995: 3994: 3950: 3944: 3943: 3904: 3898: 3897: 3853: 3844: 3843: 3841: 3839: 3825: 3819: 3818: 3800: 3767: 3761: 3760: 3742: 3709: 3703: 3702: 3692: 3674: 3665: 3659: 3658: 3632: 3617:Ann. Intern. Med 3612: 3606: 3605: 3600:. Archived from 3569: 3560: 3548: 3542: 3541: 3531: 3507: 3498: 3486: 3480: 3479: 3453: 3429: 3423: 3422: 3412: 3394: 3370: 3364: 3363: 3345: 3321: 3315: 3314: 3296: 3272: 3266: 3265: 3234:J Thromb Haemost 3228: 3222: 3221: 3211: 3201: 3177: 3171: 3170: 3126: 3120: 3119: 3104:Kumar V (2015). 3101: 3090: 3077: 3062: 3061: 3051: 3027: 3021: 3020: 3010: 3000: 2991:(4): 1205–1221. 2976: 2970: 2969: 2924: 2918: 2917: 2907: 2867: 2861: 2860: 2815: 2809: 2808: 2796: 2790: 2789: 2753: 2747: 2746: 2744: 2742: 2731: 2725: 2724: 2712: 2699: 2698: 2686: 2633: 2632: 2620: 2611: 2610: 2598: 2575: 2574: 2562: 2537: 2536: 2526: 2501:(11): CD012185. 2486: 2473: 2472: 2460: 2454: 2453: 2441: 2432: 2431: 2419: 2376: 2375: 2365: 2341: 2335: 2334: 2331: 2303: 2297: 2296: 2252: 2243: 2226: 2220: 2219: 2217: 2209: 2203: 2202: 2200: 2198: 2189:. Archived from 2183: 2177: 2176: 2166: 2157:(8): 1720–1725. 2142: 2136: 2135: 2133: 2131: 2117: 2111: 2110: 2104: 2096: 2086: 2054: 2048: 2047: 2042:. Archived from 2017: 1993: 1987: 1986: 1984: 1982: 1968: 1962: 1961: 1933: 1927: 1926: 1916: 1876: 1870: 1869: 1851: 1845: 1844: 1816: 1636:vena cava filter 1334:endothelial cell 1289:thrombophlebitis 725:Vasoconstriction 701: 588:circle of Willis 525:atherothrombosis 62:Vascular surgery 43: 31: 5785: 5784: 5780: 5779: 5778: 5776: 5775: 5774: 5760: 5759: 5758: 5749: 5698:Hemopericardium 5648: 5601: 5532:Clotting factor 5526: 5470: 5394: 5343:Bancroft's sign 5326: 5317:Virchow's triad 5288: 5238:Factor V Leiden 5194: 5171: 5161: 5131: 5122: 5104: 5030: 4987:Microangiopathy 4982:Macroangiopathy 4961: 4925: 4894:Gastric varices 4880: 4793: 4784: 4753: 4725: 4685: 4617:Aortic aneurysm 4603: 4586: 4572:Erythromelalgia 4550: 4527: 4452:Atherosclerosis 4429: 4393: 4381: 4375: 4345: 4340: 4339: 4278: 4255: 4224: 4214: 4201: 4195: 4182: 4176: 4163: 4157: 4147:Pathophysiology 4144: 4138: 4125: 4122: 4117: 4116: 4077:(13): 935–941. 4064: 4063: 4059: 4011: 4006: 4005: 3998: 3952: 3951: 3947: 3906: 3905: 3901: 3855: 3854: 3847: 3837: 3835: 3827: 3826: 3822: 3769: 3768: 3764: 3715:thromboembolism 3711: 3710: 3706: 3672: 3667: 3666: 3662: 3630:10.1.1.694.4563 3614: 3613: 3609: 3571: 3570: 3563: 3549: 3545: 3509: 3508: 3501: 3487: 3483: 3431: 3430: 3426: 3372: 3371: 3367: 3323: 3322: 3318: 3274: 3273: 3269: 3230: 3229: 3225: 3179: 3178: 3174: 3128: 3127: 3123: 3116: 3103: 3102: 3093: 3087:Wayback Machine 3078: 3065: 3029: 3028: 3024: 2978: 2977: 2973: 2926: 2925: 2921: 2869: 2868: 2864: 2817: 2816: 2812: 2802: 2797: 2793: 2755: 2754: 2750: 2740: 2738: 2733: 2732: 2728: 2718: 2713: 2702: 2692: 2687: 2636: 2626: 2621: 2614: 2604: 2599: 2578: 2568: 2563: 2540: 2488: 2487: 2476: 2466: 2461: 2457: 2447: 2442: 2435: 2425: 2420: 2379: 2343: 2342: 2338: 2332: 2305: 2304: 2300: 2254: 2253: 2246: 2236:Wayback Machine 2227: 2223: 2215: 2211: 2210: 2206: 2196: 2194: 2185: 2184: 2180: 2144: 2143: 2139: 2129: 2127: 2125:medlineplus.gov 2119: 2118: 2114: 2097: 2056: 2055: 2051: 2015:10.1.1.536.2660 1995: 1994: 1990: 1980: 1978: 1970: 1969: 1965: 1935: 1934: 1930: 1878: 1877: 1873: 1866: 1853: 1852: 1848: 1818: 1817: 1813: 1808: 1781: 1769: 1756: 1750: 1734: 1726: 1714: 1695: 1662: 1656: 1654:Anticoagulation 1648: 1603: 1597: 1570: 1564: 1539:venous thrombus 1537:will result. A 1499:myofibroblastic 1476: 1474:Natural history 1471: 1469:Pathophysiology 1443:thromboembolism 1418: 1412: 1388:gene expression 1372: 1352: 1346: 1326:Virchow's triad 1322: 1320:Virchow's triad 1316: 1311: 1086:Factor V Leiden 993:modifiable risk 878:Estrogen-based 668:Virchow's triad 657:thromboembolism 649: 634: 622: 606:coronary artery 602: 596: 575:atherosclerotic 548: 542: 513: 473:danger triangle 469:cavernous sinus 462: 456: 440:systemic sepsis 433: 401: 395: 379: 373: 337: 331: 296: 290: 282:subclavian vein 267: 261: 220: 214: 209: 203: 195: 183:thromboembolism 29: 26: 17: 12: 11: 5: 5783: 5781: 5773: 5772: 5762: 5761: 5755: 5754: 5751: 5750: 5748: 5747: 5746: 5745: 5737: 5736: 5735: 5730: 5725: 5723:Hemoperitoneum 5720: 5715: 5707: 5706: 5705: 5700: 5695: 5687: 5686: 5685: 5680: 5675: 5670: 5665: 5656: 5654: 5650: 5649: 5647: 5646: 5645: 5644: 5634: 5629: 5624: 5619: 5613: 5611: 5607: 5606: 5603: 5602: 5600: 5599: 5594: 5589: 5584: 5579: 5574: 5569: 5564: 5559: 5558: 5557: 5552: 5547: 5536: 5534: 5528: 5527: 5525: 5524: 5523: 5522: 5517: 5505: 5504: 5503: 5493: 5492: 5491: 5480: 5478: 5472: 5471: 5469: 5468: 5463: 5457: 5456: 5455: 5454: 5449: 5439: 5438: 5437: 5435:Evans syndrome 5422: 5420: 5411: 5404: 5400: 5399: 5396: 5395: 5393: 5392: 5387: 5382: 5381: 5380: 5375: 5370: 5368:Peabody's sign 5365: 5360: 5355: 5350: 5345: 5334: 5332: 5328: 5327: 5325: 5324: 5319: 5314: 5309: 5304: 5298: 5296: 5290: 5289: 5287: 5286: 5281: 5280: 5279: 5269: 5268: 5267: 5262: 5260:Thrombocytosis 5257: 5247: 5246: 5245: 5240: 5235: 5230: 5225: 5220: 5209: 5207: 5200: 5196: 5195: 5193: 5192: 5187: 5182: 5176: 5173: 5172: 5162: 5160: 5159: 5152: 5145: 5137: 5128: 5127: 5124: 5123: 5121: 5120: 5114: 5112: 5106: 5105: 5103: 5102: 5097: 5092: 5087: 5082: 5081: 5080: 5070: 5065: 5060: 5055: 5049: 5047: 5038: 5036:Blood pressure 5032: 5031: 5029: 5028: 5023: 5018: 5013: 5012: 5011: 5006: 5001: 4991: 4990: 4989: 4984: 4973: 4971: 4967: 4966: 4963: 4962: 4960: 4959: 4954: 4949: 4944: 4939: 4933: 4931: 4927: 4926: 4924: 4923: 4918: 4917: 4916: 4911: 4906: 4896: 4890: 4888: 4886:Varicose veins 4882: 4881: 4879: 4878: 4873: 4872: 4871: 4861: 4860: 4859: 4854: 4844: 4843: 4842: 4837: 4832: 4827: 4822: 4812: 4811: 4810: 4799: 4797: 4786: 4785: 4783: 4782: 4776: 4774: 4765: 4759: 4758: 4755: 4754: 4752: 4751: 4749:Spider angioma 4746: 4741: 4735: 4733: 4731:Vascular nevus 4727: 4726: 4724: 4723: 4722: 4721: 4716: 4709:Telangiectasia 4706: 4701: 4695: 4693: 4687: 4686: 4684: 4683: 4682: 4681: 4676: 4671: 4666: 4661: 4651: 4646: 4644:Aortic rupture 4641: 4636: 4635: 4634: 4629: 4624: 4609: 4607: 4605:pseudoaneurysm 4592: 4591: 4588: 4587: 4585: 4584: 4579: 4574: 4569: 4564: 4558: 4556: 4552: 4551: 4549: 4548: 4543: 4537: 4535: 4529: 4528: 4526: 4525: 4524: 4523: 4518: 4516:Oxycholesterol 4513: 4508: 4503: 4498: 4488: 4482: 4481: 4480: 4479: 4474: 4469: 4464: 4459: 4448: 4446: 4437: 4431: 4430: 4428: 4427: 4422: 4421: 4420: 4409: 4407: 4398: 4383: 4382: 4376: 4374: 4373: 4366: 4359: 4351: 4342: 4341: 4338: 4337: 4326: 4299: 4279: 4274: 4273: 4271: 4270:Classification 4264: 4263: 4239: 4237: 4223: 4222:External links 4220: 4219: 4218: 4212: 4199: 4193: 4180: 4174: 4161: 4155: 4142: 4136: 4121: 4118: 4115: 4114: 4057: 4022:(3): 269–276. 3996: 3961:(2): 143–152. 3945: 3899: 3864:(5): 637–647. 3845: 3820: 3762: 3725:(5): 227–235. 3704: 3660: 3607: 3561: 3543: 3499: 3481: 3424: 3365: 3336:(3): 484–490. 3316: 3267: 3240:(7): 1116–20. 3223: 3172: 3137:(2): 151–158. 3121: 3114: 3091: 3063: 3042:(6): 753–762. 3022: 2971: 2919: 2882:(6): e011272. 2862: 2827:(5): 591–601. 2810: 2801:, p. 876. 2791: 2764:(8): 1879–83. 2748: 2726: 2717:, p. 329. 2700: 2691:, p. 875. 2634: 2612: 2603:, p. 307. 2576: 2567:, p. 320. 2538: 2474: 2465:, p. 874. 2455: 2446:, p. 306. 2433: 2424:, p. 960. 2377: 2356:(4): 746–757. 2336: 2298: 2244: 2221: 2204: 2178: 2137: 2112: 2069:(5): 1729–64. 2049: 1988: 1963: 1928: 1871: 1864: 1846: 1827:(9): 938–949. 1810: 1809: 1807: 1804: 1803: 1802: 1797: 1792: 1787: 1780: 1777: 1768: 1765: 1752:Main article: 1749: 1746: 1733: 1730: 1725: 1722: 1713: 1710: 1694: 1691: 1673:anticoagulants 1658:Main article: 1655: 1652: 1647: 1644: 1599:Main article: 1596: 1593: 1563: 1560: 1552:macular oedema 1475: 1472: 1470: 1467: 1411: 1408: 1396:thrombomodulin 1371: 1368: 1348:Main article: 1345: 1342: 1318:Main article: 1315: 1312: 1310: 1307: 1304: 1303: 1301: 1298: 1294: 1293: 1291: 1285: 1281: 1280: 1278: 1276: 1272: 1271: 1269: 1266: 1262: 1261: 1259: 1257: 1255:Thrombophilias 1251: 1250: 1248: 1246: 1242: 1241: 1239: 1237: 1233: 1232: 1230: 1228: 1224: 1223: 1221: 1219: 1213: 1212: 1210: 1208: 1204: 1203: 1201: 1199: 1196:Erythropoiesis 1192: 1191: 1189: 1187: 1183: 1182: 1180: 1177: 1173: 1172: 1170: 1167: 1161: 1160: 1158: 1155: 1136: 1135: 1133: 1130: 1124: 1123: 1121: 1115: 1108: 1107: 1105: 1102: 1095: 1094: 1092: 1089: 1082: 1081: 1079: 1076: 1070: 1069: 1067: 1061: 1050: 1049: 1047: 1045: 1039: 1038: 1036: 1034: 1028: 1027: 1025: 1023: 1017: 1016: 1014: 1012: 1008: 1007: 1005: 1003: 997: 996: 994: 991: 987: 986: 984: 982: 976: 975: 973: 971: 962: 961: 959: 957: 951: 950: 948: 946: 942: 941: 939: 937: 931: 930: 928: 926: 925:Long surgeries 922: 921: 919: 917: 909: 908: 906: 904: 900: 899: 897: 894: 888: 887: 885: 882: 875: 874: 872: 870: 864: 863: 861: 859: 855: 854: 852: 850: 848:Varicose veins 844: 843: 841: 839: 835: 834: 832: 829: 823: 822: 820: 818: 812: 811: 809: 807: 801: 800: 798: 796: 792: 791: 789: 786: 780: 779: 777: 774: 770: 769: 767: 764: 760: 759: 757: 755: 751: 750: 748: 746: 742: 741: 739: 736: 732: 731: 729: 727: 721: 720: 718: 716: 712: 711: 708: 705: 693: 692: 685: 678: 648: 645: 633: 630: 621: 618: 616:is initiated. 598:Main article: 595: 592: 544:Main article: 541: 538: 512: 509: 458:Main article: 455: 452: 432: 429: 425:mortality rate 397:Main article: 394: 391: 375:Main article: 372: 369: 361:diverticulitis 333:Main article: 330: 327: 319:enlarged liver 311:abdominal pain 292:Main article: 289: 286: 263:Main article: 260: 257: 249: 248: 245: 242: 216:Main article: 213: 210: 205:Main article: 202: 199: 194: 191: 83: 82: 79: 73: 72: 59: 53: 52: 45: 44: 36: 35: 27: 15: 13: 10: 9: 6: 4: 3: 2: 5782: 5771: 5768: 5767: 5765: 5744: 5741: 5740: 5738: 5734: 5733:Hematosalpinx 5731: 5729: 5726: 5724: 5721: 5719: 5716: 5714: 5711: 5710: 5708: 5704: 5701: 5699: 5696: 5694: 5691: 5690: 5688: 5684: 5681: 5679: 5676: 5674: 5671: 5669: 5666: 5664: 5661: 5660: 5658: 5657: 5655: 5651: 5643: 5640: 5639: 5638: 5635: 5633: 5630: 5628: 5625: 5623: 5620: 5618: 5615: 5614: 5612: 5608: 5598: 5595: 5593: 5590: 5588: 5585: 5583: 5580: 5578: 5575: 5573: 5570: 5568: 5565: 5563: 5560: 5556: 5553: 5551: 5548: 5546: 5543: 5542: 5541: 5538: 5537: 5535: 5533: 5529: 5521: 5518: 5516: 5513: 5512: 5511: 5510: 5506: 5502: 5499: 5498: 5497: 5494: 5490: 5487: 5486: 5485: 5482: 5481: 5479: 5477: 5473: 5467: 5464: 5462: 5459: 5458: 5453: 5450: 5448: 5445: 5444: 5443: 5440: 5436: 5433: 5432: 5431: 5427: 5424: 5423: 5421: 5419: 5415: 5412: 5408: 5405: 5401: 5391: 5388: 5386: 5383: 5379: 5376: 5374: 5371: 5369: 5366: 5364: 5361: 5359: 5358:Louvel's sign 5356: 5354: 5353:Lisker's sign 5351: 5349: 5346: 5344: 5341: 5340: 5339: 5336: 5335: 5333: 5329: 5323: 5320: 5318: 5315: 5313: 5310: 5308: 5305: 5303: 5302:Thrombophilia 5300: 5299: 5297: 5295: 5291: 5285: 5282: 5278: 5275: 5274: 5273: 5270: 5266: 5263: 5261: 5258: 5256: 5253: 5252: 5251: 5248: 5244: 5241: 5239: 5236: 5234: 5231: 5229: 5226: 5224: 5221: 5219: 5216: 5215: 5214: 5211: 5210: 5208: 5204: 5201: 5197: 5191: 5188: 5186: 5183: 5181: 5178: 5177: 5174: 5170: 5166: 5163:Disorders of 5158: 5153: 5151: 5146: 5144: 5139: 5138: 5135: 5119: 5116: 5115: 5113: 5111: 5107: 5101: 5098: 5096: 5093: 5091: 5088: 5086: 5083: 5079: 5076: 5075: 5074: 5071: 5069: 5066: 5064: 5061: 5059: 5056: 5054: 5051: 5050: 5048: 5046: 5042: 5039: 5037: 5033: 5027: 5024: 5022: 5019: 5017: 5014: 5010: 5007: 5005: 5002: 5000: 4997: 4996: 4995: 4992: 4988: 4985: 4983: 4980: 4979: 4978: 4975: 4974: 4972: 4968: 4958: 4955: 4953: 4950: 4948: 4945: 4943: 4940: 4938: 4935: 4934: 4932: 4928: 4922: 4919: 4915: 4912: 4910: 4907: 4905: 4904:Caput medusae 4902: 4901: 4900: 4897: 4895: 4892: 4891: 4889: 4887: 4883: 4877: 4874: 4870: 4867: 4866: 4865: 4862: 4858: 4855: 4853: 4850: 4849: 4848: 4845: 4841: 4838: 4836: 4833: 4831: 4828: 4826: 4823: 4821: 4818: 4817: 4816: 4813: 4809: 4806: 4805: 4804: 4801: 4800: 4798: 4796: 4791: 4787: 4781: 4778: 4777: 4775: 4773: 4769: 4766: 4764: 4760: 4750: 4747: 4745: 4742: 4740: 4737: 4736: 4734: 4732: 4728: 4720: 4717: 4715: 4712: 4711: 4710: 4707: 4705: 4702: 4700: 4697: 4696: 4694: 4692: 4688: 4680: 4677: 4675: 4672: 4670: 4667: 4665: 4662: 4660: 4657: 4656: 4655: 4652: 4650: 4647: 4645: 4642: 4640: 4637: 4633: 4630: 4628: 4625: 4623: 4620: 4619: 4618: 4614: 4611: 4610: 4608: 4606: 4601: 4597: 4593: 4583: 4580: 4578: 4575: 4573: 4570: 4568: 4567:Degos disease 4565: 4563: 4560: 4559: 4557: 4553: 4547: 4544: 4542: 4539: 4538: 4536: 4534: 4530: 4522: 4519: 4517: 4514: 4512: 4509: 4507: 4504: 4502: 4499: 4497: 4494: 4493: 4492: 4489: 4487: 4484: 4483: 4478: 4475: 4473: 4470: 4468: 4465: 4463: 4460: 4458: 4455: 4454: 4453: 4450: 4449: 4447: 4445: 4441: 4438: 4436: 4432: 4426: 4423: 4419: 4416: 4415: 4414: 4411: 4410: 4408: 4406: 4402: 4399: 4397: 4392: 4388: 4384: 4379: 4372: 4367: 4365: 4360: 4358: 4353: 4352: 4349: 4336: 4332: 4331: 4327: 4325: 4321: 4317: 4313: 4309: 4308: 4304: 4300: 4298: 4294: 4290: 4289: 4285: 4281: 4280: 4277: 4272: 4268: 4262: 4258: 4253: 4249: 4248: 4243: 4238: 4235: 4230: 4226: 4225: 4221: 4215: 4209: 4205: 4200: 4196: 4190: 4186: 4181: 4177: 4171: 4167: 4162: 4158: 4152: 4148: 4143: 4139: 4133: 4129: 4124: 4123: 4119: 4110: 4106: 4101: 4096: 4092: 4088: 4084: 4080: 4076: 4072: 4068: 4061: 4058: 4053: 4049: 4045: 4041: 4037: 4033: 4029: 4025: 4021: 4017: 4010: 4003: 4001: 3997: 3992: 3988: 3984: 3980: 3976: 3972: 3968: 3964: 3960: 3956: 3949: 3946: 3941: 3937: 3933: 3929: 3925: 3921: 3917: 3913: 3909: 3903: 3900: 3895: 3891: 3887: 3883: 3879: 3875: 3871: 3867: 3863: 3859: 3852: 3850: 3846: 3834: 3830: 3824: 3821: 3816: 3812: 3808: 3804: 3799: 3794: 3790: 3786: 3782: 3778: 3774: 3766: 3763: 3758: 3754: 3750: 3746: 3741: 3736: 3732: 3728: 3724: 3720: 3716: 3708: 3705: 3700: 3696: 3691: 3686: 3682: 3678: 3671: 3664: 3661: 3656: 3652: 3648: 3644: 3640: 3636: 3631: 3626: 3623:(4): 278–88. 3622: 3618: 3611: 3608: 3603: 3599: 3595: 3591: 3587: 3583: 3579: 3575: 3568: 3566: 3562: 3558: 3557: 3552: 3547: 3544: 3539: 3535: 3530: 3525: 3521: 3517: 3513: 3506: 3504: 3500: 3496: 3495: 3490: 3485: 3482: 3477: 3473: 3469: 3465: 3461: 3457: 3452: 3447: 3443: 3439: 3435: 3428: 3425: 3420: 3416: 3411: 3406: 3402: 3398: 3393: 3388: 3384: 3380: 3376: 3369: 3366: 3361: 3357: 3353: 3349: 3344: 3339: 3335: 3331: 3327: 3320: 3317: 3312: 3308: 3304: 3300: 3295: 3290: 3286: 3282: 3278: 3271: 3268: 3263: 3259: 3255: 3251: 3247: 3243: 3239: 3235: 3227: 3224: 3219: 3215: 3210: 3205: 3200: 3195: 3191: 3187: 3183: 3176: 3173: 3168: 3164: 3160: 3156: 3152: 3148: 3144: 3140: 3136: 3132: 3125: 3122: 3117: 3111: 3107: 3100: 3098: 3096: 3092: 3088: 3084: 3081: 3076: 3074: 3072: 3070: 3068: 3064: 3059: 3055: 3050: 3045: 3041: 3037: 3033: 3026: 3023: 3018: 3014: 3009: 3004: 2999: 2994: 2990: 2986: 2982: 2975: 2972: 2967: 2963: 2959: 2955: 2951: 2947: 2943: 2939: 2935: 2931: 2923: 2920: 2915: 2911: 2906: 2901: 2897: 2893: 2889: 2885: 2881: 2877: 2873: 2866: 2863: 2858: 2854: 2850: 2846: 2842: 2838: 2834: 2830: 2826: 2822: 2814: 2811: 2806: 2800: 2795: 2792: 2787: 2783: 2779: 2775: 2771: 2767: 2763: 2759: 2752: 2749: 2736: 2735:"Pacing wire" 2730: 2727: 2722: 2716: 2711: 2709: 2707: 2705: 2701: 2696: 2690: 2685: 2683: 2681: 2679: 2677: 2675: 2673: 2671: 2669: 2667: 2665: 2663: 2661: 2659: 2657: 2655: 2653: 2651: 2649: 2647: 2645: 2643: 2641: 2639: 2635: 2630: 2624: 2619: 2617: 2613: 2608: 2602: 2597: 2595: 2593: 2591: 2589: 2587: 2585: 2583: 2581: 2577: 2572: 2566: 2561: 2559: 2557: 2555: 2553: 2551: 2549: 2547: 2545: 2543: 2539: 2534: 2530: 2525: 2520: 2516: 2512: 2508: 2504: 2500: 2496: 2492: 2485: 2483: 2481: 2479: 2475: 2470: 2464: 2459: 2456: 2451: 2445: 2440: 2438: 2434: 2429: 2423: 2418: 2416: 2414: 2412: 2410: 2408: 2406: 2404: 2402: 2400: 2398: 2396: 2394: 2392: 2390: 2388: 2386: 2384: 2382: 2378: 2373: 2369: 2364: 2359: 2355: 2351: 2347: 2340: 2337: 2329: 2325: 2321: 2317: 2313: 2309: 2302: 2299: 2294: 2290: 2286: 2282: 2278: 2274: 2270: 2266: 2262: 2258: 2251: 2249: 2245: 2241: 2237: 2233: 2230: 2225: 2222: 2214: 2208: 2205: 2192: 2188: 2182: 2179: 2174: 2170: 2165: 2160: 2156: 2152: 2148: 2141: 2138: 2126: 2122: 2116: 2113: 2108: 2102: 2094: 2090: 2085: 2080: 2076: 2072: 2068: 2064: 2060: 2053: 2050: 2045: 2041: 2037: 2033: 2029: 2025: 2021: 2016: 2011: 2007: 2003: 1999: 1992: 1989: 1977: 1973: 1967: 1964: 1959: 1955: 1951: 1947: 1944:(2): 89–127. 1943: 1939: 1932: 1929: 1924: 1920: 1915: 1910: 1906: 1902: 1898: 1894: 1891:(3): 77–104. 1890: 1886: 1882: 1875: 1872: 1867: 1861: 1857: 1850: 1847: 1842: 1838: 1834: 1830: 1826: 1822: 1815: 1812: 1805: 1801: 1798: 1796: 1793: 1791: 1788: 1786: 1783: 1782: 1778: 1776: 1774: 1766: 1764: 1762: 1755: 1747: 1745: 1743: 1739: 1731: 1729: 1723: 1721: 1719: 1711: 1709: 1707: 1703: 1699: 1692: 1690: 1688: 1684: 1679: 1674: 1670: 1666: 1661: 1660:Anticoagulant 1653: 1651: 1645: 1643: 1641: 1637: 1633: 1629: 1625: 1621: 1617: 1613: 1608: 1602: 1594: 1592: 1590: 1586: 1581: 1579: 1575: 1569: 1561: 1559: 1557: 1556:visual acuity 1553: 1549: 1545: 1540: 1536: 1532: 1526: 1524: 1520: 1519:smooth muscle 1516: 1512: 1508: 1507:wound healing 1504: 1500: 1496: 1492: 1491:wound healing 1486: 1484: 1480: 1473: 1468: 1466: 1464: 1460: 1456: 1452: 1448: 1444: 1440: 1436: 1432: 1431:venous stasis 1422: 1417: 1409: 1407: 1403: 1401: 1397: 1393: 1389: 1385: 1381: 1380:tissue factor 1377: 1369: 1367: 1365: 1361: 1357: 1356:thrombophilia 1351: 1350:Thrombophilia 1343: 1341: 1339: 1335: 1331: 1330:thrombophilia 1327: 1321: 1313: 1308: 1302: 1299: 1296: 1295: 1292: 1290: 1286: 1283: 1282: 1279: 1277: 1274: 1273: 1270: 1267: 1264: 1263: 1260: 1258: 1256: 1253: 1252: 1249: 1247: 1244: 1243: 1240: 1238: 1235: 1234: 1231: 1229: 1226: 1225: 1222: 1220: 1218: 1215: 1214: 1211: 1209: 1206: 1205: 1202: 1200: 1197: 1194: 1193: 1190: 1188: 1185: 1184: 1181: 1178: 1175: 1174: 1171: 1168: 1166: 1163: 1162: 1159: 1156: 1154: 1150: 1146: 1142: 1138: 1137: 1134: 1131: 1129: 1126: 1125: 1122: 1120: 1116: 1114: 1110: 1109: 1106: 1103: 1100: 1097: 1096: 1093: 1090: 1087: 1084: 1083: 1080: 1077: 1075: 1072: 1071: 1068: 1066: 1062: 1059: 1055: 1052: 1051: 1048: 1046: 1044: 1041: 1040: 1037: 1035: 1033: 1030: 1029: 1026: 1024: 1022: 1019: 1018: 1015: 1013: 1010: 1009: 1006: 1004: 1002: 999: 998: 995: 992: 989: 988: 985: 983: 981: 978: 977: 974: 972: 970: 967: 964: 963: 960: 958: 956: 953: 952: 949: 947: 944: 943: 940: 938: 936: 933: 932: 929: 927: 924: 923: 920: 918: 915: 911: 910: 907: 905: 902: 901: 898: 895: 893: 890: 889: 886: 883: 881: 877: 876: 873: 871: 869: 866: 865: 862: 860: 857: 856: 853: 851: 849: 846: 845: 842: 840: 837: 836: 833: 830: 828: 825: 824: 821: 819: 817: 814: 813: 810: 808: 806: 803: 802: 799: 797: 794: 793: 790: 787: 785: 782: 781: 778: 775: 772: 771: 768: 765: 762: 761: 758: 756: 754:Heart failure 753: 752: 749: 747: 744: 743: 740: 737: 734: 733: 730: 728: 726: 723: 722: 719: 717: 714: 713: 709: 706: 703: 702: 696: 690: 686: 683: 680:vessel wall { 679: 676: 673: 672: 671: 669: 664: 662: 658: 654: 646: 644: 642: 638: 631: 629: 627: 620:Limb ischemia 619: 617: 615: 611: 607: 601: 593: 591: 589: 585: 581: 576: 571: 569: 565: 561: 552: 547: 539: 537: 535: 530: 526: 522: 518: 510: 508: 506: 502: 498: 497:double vision 494: 493:Streptococcal 490: 489:Staphyloccoal 486: 482: 478: 474: 470: 466: 461: 453: 451: 449: 445: 441: 437: 430: 428: 426: 422: 418: 414: 410: 406: 400: 392: 390: 388: 384: 378: 370: 368: 366: 362: 358: 354: 350: 346: 342: 336: 328: 326: 324: 320: 316: 312: 308: 304: 300: 295: 287: 285: 283: 279: 278:axillary vein 275: 271: 266: 258: 256: 254: 246: 243: 240: 239: 238: 235: 233: 229: 225: 219: 211: 208: 200: 198: 192: 190: 188: 184: 180: 176: 172: 168: 164: 160: 156: 152: 148: 143: 141: 136: 132: 128: 124: 120: 116: 112: 108: 104: 100: 96: 93: 92:Ancient Greek 89: 80: 78: 74: 71: 67: 63: 60: 58: 54: 50: 46: 42: 37: 32: 24: 19: 5743:Hemarthrosis 5507: 5495: 5483: 5373:Pratt's sign 5311: 5293: 5185:coagulopathy 5045:Hypertension 5015: 4957:Venous ulcer 4863: 4846: 4814: 4802: 4772:Inflammation 4653: 4612: 4501:Hyperplastic 4462:Fatty streak 4405:Inflammation 4328: 4301: 4282: 4245: 4203: 4184: 4165: 4146: 4127: 4120:Bibliography 4074: 4070: 4060: 4019: 4015: 3958: 3954: 3948: 3915: 3911: 3902: 3861: 3857: 3836:. Retrieved 3832: 3823: 3783:(1): 11–20. 3780: 3776: 3765: 3740:11343/285435 3722: 3718: 3707: 3680: 3676: 3663: 3620: 3616: 3610: 3602:the original 3581: 3577: 3554: 3546: 3522:(3): 398–9. 3519: 3515: 3492: 3484: 3441: 3437: 3427: 3382: 3378: 3368: 3333: 3329: 3319: 3284: 3280: 3270: 3237: 3233: 3226: 3189: 3185: 3175: 3134: 3130: 3124: 3105: 3039: 3035: 3025: 2988: 2984: 2974: 2933: 2929: 2922: 2879: 2875: 2865: 2824: 2820: 2813: 2794: 2761: 2757: 2751: 2741:December 18, 2739:. Retrieved 2729: 2498: 2494: 2458: 2353: 2349: 2339: 2311: 2307: 2301: 2260: 2256: 2239: 2224: 2207: 2195:. Retrieved 2191:the original 2181: 2154: 2150: 2140: 2128:. Retrieved 2124: 2115: 2101:cite journal 2066: 2062: 2052: 2044:the original 2005: 2001: 1991: 1979:. Retrieved 1975: 1966: 1941: 1937: 1931: 1888: 1884: 1874: 1855: 1849: 1824: 1820: 1814: 1770: 1757: 1735: 1727: 1715: 1698:Thrombolysis 1696: 1693:Thrombolysis 1663: 1649: 1615: 1604: 1582: 1571: 1562:Embolization 1527: 1523:vasa vasorum 1487: 1479:Fibrinolysis 1477: 1463:ThroLy score 1451:malignancies 1428: 1404: 1392:downregulate 1373: 1355: 1353: 1328:which lists 1323: 1314:Pathogenesis 1043:Polycythemia 935:Pacing wires 805:Dysrhythmias 773:Plaster cast 694: 665: 661:inflammation 650: 635: 623: 603: 572: 570:(a bleed). 562:, thrombus, 557: 524: 514: 463: 436:Jugular vein 434: 402: 380: 353:pancreatitis 345:hypertension 338: 303:hepatic vein 297: 268: 250: 236: 232:femoral vein 221: 196: 144: 113:through the 107:blood vessel 99:(thrĂłmbōsis) 98: 95: 87: 86: 18: 5496:aggregation 5378:Rose's sign 5348:Homans sign 5180:Coagulation 5110:Hypotension 4654:head / neck 4506:Cholesterol 4396:capillaries 4240:‹ The 3798:2066/153000 2936:: 352–358. 2197:December 8, 1605:The use of 1119:blood clots 784:Dehydration 710:References 682:endothelial 632:Other sites 448:papilledema 70:pulmonology 5770:Hematology 5728:Hematocele 5693:Hemothorax 5668:Hemoptysis 5540:Hemophilia 5312:Thrombosis 5026:Vasculitis 5016:Thrombosis 4977:Angiopathy 4921:Varicocele 4914:Hemorrhoid 4744:Halo nevus 4600:dissection 4391:arterioles 4257:Thrombosis 4234:Thrombosis 3677:The Lancet 3192:(3): 566. 2063:Hepatology 2008:(1): 1–9. 1806:References 1704:including 1630:recommend 1595:Prevention 1578:infarction 1535:infarction 1416:Blood flow 1338:blood flow 1141:factors II 1060:deficiency 990:Immobility 831:modifiable 788:modifiable 766:modifiable 568:hemorrhage 505:meningitis 383:renal vein 135:blood clot 133:to form a 103:blood clot 90:(from 88:Thrombosis 34:Thrombosis 5718:Hemobilia 5663:Epistaxis 5250:Platelets 4780:Phlebitis 4521:Trans fat 4457:Foam cell 4413:Arteritis 4380:(vessels) 4091:0195-668X 4052:149537443 4036:1073-2322 3975:1747-4930 3932:0028-4793 3908:Yellon DM 3878:0007-1323 3833:Drugs.com 3625:CiteSeerX 3460:0361-8609 3401:0006-4971 3352:0732-183X 3303:1538-7933 3167:207486815 3151:1744-7631 2950:1874-1754 2896:2047-9980 2841:1097-6760 2601:Moliterno 2515:1469-493X 2444:Moliterno 2293:232242365 2277:0098-7484 2010:CiteSeerX 1950:0039-6087 1905:2288-7970 1646:Treatment 1515:platelets 1400:protein C 1309:Mechanism 1139:Elevated 1111:Elevated 1054:Protein C 969:catheters 776:transient 584:vertebral 427:is 4.3%. 357:cirrhosis 228:deep vein 226:within a 127:platelets 105:inside a 97:θρόμβωσις 57:Specialty 5764:Category 5709:abdomen 5632:Petechia 5627:Hematoma 5617:Bleeding 5484:adhesion 5410:By cause 5403:Bleeding 5307:Thrombus 5206:By cause 5199:Clotting 5169:clotting 5165:bleeding 4994:Embolism 4596:Aneurysm 4533:Stenosis 4467:Atheroma 4418:Aortitis 4387:Arteries 4242:template 4109:27118196 4044:32045394 3991:25953179 3983:25598025 3940:17855673 3894:34608929 3807:25517348 3757:73433650 3749:30739331 3699:22137798 3655:27605124 3647:17310052 3598:15383478 3538:18296598 3468:27380861 3419:18216292 3360:16421425 3311:20738765 3262:19395326 3254:24819040 3218:32121387 3159:26558419 3083:Archived 3058:27354721 3017:32869161 2966:52282745 2958:30223374 2914:31112443 2857:52144033 2849:30172448 2778:16102055 2715:Copstead 2565:Copstead 2533:27820879 2372:19298450 2328:22670905 2285:33724327 2232:Archived 2173:16002765 2093:19399912 2032:15644039 1958:18108679 1923:27699156 1841:18753650 1779:See also 1740:such as 1665:Warfarin 1589:necrosis 1585:ischemia 1531:ischemia 1455:leukemia 1453:such as 966:Dialysis 586:and the 560:ischemia 521:atheroma 481:inferior 477:superior 421:MRI scan 413:seizures 253:swelling 179:embolism 171:necrosis 167:ischemia 155:arteries 153:) or in 77:Symptoms 49:Cyanosis 5678:Hyphema 5653:By site 5637:Purpura 5331:By site 4815:abdomen 4496:Hyaline 4335:D013927 4244:below ( 4100:5381598 3886:8044536 3838:June 9, 3815:9499117 3476:1724916 3410:2384124 3209:7139427 3186:Cancers 2905:6475051 2799:Brunner 2786:6651339 2689:Brunner 2524:6464761 2463:Brunner 2422:Hoffman 2130:May 27, 2084:6697263 2040:5673778 1981:July 5, 1972:"shunt" 1914:5045251 1742:aspirin 1712:Surgery 1607:heparin 1574:embolus 1568:Embolus 1483:plasmin 1447:Cancers 1056:and/or 1021:Cancers 858:Surgery 827:Obesity 610:infarct 564:embolus 315:ascites 175:embolus 140:embolus 5739:joint 5689:torso 5622:Bruise 5545:A/VIII 4261:Curlie 4247:Curlie 4210:  4191:  4172:  4153:  4134:  4107:  4097:  4089:  4050:  4042:  4034:  3989:  3981:  3973:  3938:  3930:  3892:  3884:  3876:  3813:  3805:  3755:  3747:  3697:  3653:  3645:  3627:  3596:  3536:  3474:  3466:  3458:  3417:  3407:  3399:  3358:  3350:  3309:  3301:  3260:  3252:  3216:  3206:  3165:  3157:  3149:  3112:  3056:  3015:  3008:458881 3005:  2964:  2956:  2948:  2912:  2902:  2894:  2855:  2847:  2839:  2784:  2776:  2531:  2521:  2513:  2370:  2326:  2291:  2283:  2275:  2171:  2151:Stroke 2091:  2081:  2038:  2030:  2012:  1956:  1948:  1921:  1911:  1903:  1862:  1839:  1406:flow. 1101:defect 1088:defect 1032:Sepsis 914:artery 868:Trauma 745:Stroke 704:Factor 647:Causes 546:Stroke 540:Stroke 517:artery 501:squint 446:, and 405:stroke 387:kidney 323:shunts 131:fibrin 123:artery 121:or an 5659:head 5294:Clots 4930:Other 4763:Veins 4613:torso 4555:Other 4324:671.9 4320:671.5 4312:437.6 4048:S2CID 4016:SHOCK 4012:(PDF) 3987:S2CID 3890:S2CID 3811:S2CID 3753:S2CID 3673:(PDF) 3651:S2CID 3578:Chest 3472:S2CID 3379:Blood 3258:S2CID 3163:S2CID 3036:Blood 2962:S2CID 2853:S2CID 2782:S2CID 2623:Abele 2289:S2CID 2238:From 2216:(PDF) 2036:S2CID 1503:lumen 1113:PAI-1 816:Shock 707:Notes 349:liver 147:veins 111:blood 94: 5555:C/XI 5550:B/IX 5167:and 4864:head 4394:and 4330:MeSH 4307:9-CM 4208:ISBN 4189:ISBN 4170:ISBN 4151:ISBN 4132:ISBN 4105:PMID 4087:ISSN 4040:PMID 4032:ISSN 3979:PMID 3971:ISSN 3936:PMID 3928:ISSN 3882:PMID 3874:ISSN 3840:2020 3803:PMID 3745:PMID 3695:PMID 3643:PMID 3594:PMID 3534:PMID 3464:PMID 3456:ISSN 3415:PMID 3397:ISSN 3356:PMID 3348:ISSN 3307:PMID 3299:ISSN 3250:PMID 3214:PMID 3155:PMID 3147:ISSN 3110:ISBN 3054:PMID 3013:PMID 2954:PMID 2946:ISSN 2910:PMID 2892:ISSN 2845:PMID 2837:ISSN 2805:help 2774:PMID 2743:2016 2721:help 2695:help 2629:help 2607:help 2571:help 2529:PMID 2511:ISSN 2499:2016 2469:help 2450:help 2428:help 2368:PMID 2324:PMID 2281:PMID 2273:ISSN 2257:JAMA 2199:2015 2169:PMID 2132:2019 2107:link 2089:PMID 2028:PMID 1983:2021 1954:PMID 1946:ISSN 1919:PMID 1901:ISSN 1860:ISBN 1837:PMID 1685:and 1671:are 1667:and 1554:and 1495:scar 1145:VIII 479:and 317:and 224:clot 169:and 119:vein 5447:TTP 5430:ITP 5272:DIC 4511:LDL 4316:453 4303:ICD 4297:I82 4293:I80 4284:ICD 4259:at 4095:PMC 4079:doi 4024:doi 3963:doi 3920:doi 3916:357 3866:doi 3793:hdl 3785:doi 3781:372 3735:hdl 3727:doi 3723:210 3717:". 3685:doi 3681:379 3635:doi 3621:146 3586:doi 3582:126 3524:doi 3446:doi 3405:PMC 3387:doi 3383:111 3338:doi 3289:doi 3242:doi 3204:PMC 3194:doi 3139:doi 3044:doi 3040:128 3003:PMC 2993:doi 2938:doi 2934:271 2900:PMC 2884:doi 2829:doi 2766:doi 2519:PMC 2503:doi 2358:doi 2316:doi 2312:366 2265:doi 2261:325 2159:doi 2079:PMC 2071:doi 2020:doi 1909:PMC 1893:doi 1829:doi 1825:359 1533:or 1449:or 1362:or 1011:Age 663:. 491:or 419:or 363:or 280:or 274:arm 234:. 5766:: 5442:TM 5428:: 4615:: 4598:/ 4389:, 4333:: 4322:, 4318:, 4314:, 4310:: 4291:: 4288:10 4103:. 4093:. 4085:. 4075:38 4073:. 4069:. 4046:. 4038:. 4030:. 4020:53 4018:. 4014:. 3999:^ 3985:. 3977:. 3969:. 3959:10 3957:. 3934:. 3926:. 3914:. 3888:. 3880:. 3872:. 3862:81 3860:. 3848:^ 3831:. 3809:. 3801:. 3791:. 3779:. 3775:. 3751:. 3743:. 3733:. 3721:. 3693:. 3679:. 3675:. 3649:. 3641:. 3633:. 3619:. 3592:. 3580:. 3576:. 3564:^ 3553:. 3532:. 3520:28 3518:. 3514:. 3502:^ 3491:. 3470:. 3462:. 3454:. 3442:91 3440:. 3436:. 3413:. 3403:. 3395:. 3381:. 3377:. 3354:. 3346:. 3334:24 3332:. 3328:. 3305:. 3297:. 3283:. 3279:. 3256:. 3248:. 3238:12 3236:. 3212:. 3202:. 3190:12 3188:. 3184:. 3161:. 3153:. 3145:. 3135:20 3133:. 3094:^ 3066:^ 3052:. 3038:. 3034:. 3011:. 3001:. 2989:39 2987:. 2983:. 2960:. 2952:. 2944:. 2932:. 2908:. 2898:. 2890:. 2878:. 2874:. 2851:. 2843:. 2835:. 2825:72 2823:. 2780:. 2772:. 2760:. 2703:^ 2637:^ 2615:^ 2579:^ 2541:^ 2527:. 2517:. 2509:. 2497:. 2493:. 2477:^ 2436:^ 2380:^ 2366:. 2352:. 2348:. 2322:. 2310:. 2287:. 2279:. 2271:. 2259:. 2247:^ 2167:. 2155:36 2153:. 2149:. 2123:. 2103:}} 2099:{{ 2087:. 2077:. 2067:49 2065:. 2061:. 2034:. 2026:. 2018:. 2006:21 2004:. 2000:. 1974:. 1952:. 1942:88 1940:. 1917:. 1907:. 1899:. 1889:32 1887:. 1883:. 1835:. 1823:. 1720:. 1626:, 1525:. 1485:. 1465:. 1445:. 1332:, 1153:XI 1151:, 1149:IX 1147:, 1143:, 691:). 643:. 628:. 582:, 527:. 507:. 499:, 487:. 442:, 417:CT 389:. 367:. 359:, 355:, 325:. 313:, 142:. 68:, 64:, 5156:e 5149:t 5142:v 4792:/ 4602:/ 4370:e 4363:t 4356:v 4305:- 4295:- 4286:- 4276:D 4216:. 4197:. 4178:. 4159:. 4140:. 4111:. 4081:: 4054:. 4026:: 3993:. 3965:: 3942:. 3922:: 3896:. 3868:: 3842:. 3817:. 3795:: 3787:: 3759:. 3737:: 3729:: 3701:. 3687:: 3657:. 3637:: 3588:: 3540:. 3526:: 3478:. 3448:: 3421:. 3389:: 3362:. 3340:: 3313:. 3291:: 3285:8 3264:. 3244:: 3220:. 3196:: 3169:. 3141:: 3118:. 3060:. 3046:: 3019:. 2995:: 2968:. 2940:: 2916:. 2886:: 2880:8 2859:. 2831:: 2807:) 2788:. 2768:: 2762:3 2745:. 2723:) 2697:) 2631:) 2625:. 2609:) 2573:) 2535:. 2505:: 2471:) 2452:) 2430:) 2374:. 2360:: 2354:9 2330:. 2318:: 2295:. 2267:: 2218:. 2201:. 2175:. 2161:: 2134:. 2109:) 2095:. 2073:: 2022:: 1985:. 1960:. 1925:. 1895:: 1868:. 1843:. 1831:: 1058:S 666:" 157:( 149:( 25:.

Index

Thrombosis (journal)

Cyanosis
Specialty
Vascular surgery
internal medicine
pulmonology
Symptoms
Ancient Greek
blood clot
blood vessel
blood
circulatory system
vein
artery
platelets
fibrin
blood clot
embolus
veins
venous thrombosis
arteries
arterial thrombosis
deep vein thrombosis
ischemia
necrosis
embolus
embolism
thromboembolism
pulmonary embolism

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑