554:
98:
Mean systemic pressure increases if there is an increase in blood volume or if there is a decrease in venous compliance (where blood is shifted from the veins to the arteries). An increase in mean systemic pressure is reflected in a shift of the vascular function curve to the right. Mean systemic
70:
MSP is measured in two ways experimentally, and as a result has two alternative naming conventions. MSFP is measured after clamping the aortic root and the great veins at point of entry to right atrium. On the other hand, MCFP is measured experimentally by briefly inducing
99:
pressure is decreased by a decrease in blood volume or by an increase in venous compliance (where blood is shifted from the arteries to the veins). A decrease in mean systemic pressure is reflected in a shift of the vascular function curve to the left.
300:
163:
52:
when there is no blood motion. The value of MSP in animal experimental models is approximately 7 mm Hg. It is an indicator of how full the circulatory system is (i.e. the
216:
595:
450:
619:
509:
Rothe CF, CF; Maass-Moreno R (Mar 1994). "Gastrointestinal hemodynamics during compensation for hemorrhage and measurement of P
588:
399:
Tabrizchi, R; Pang CC (May 1992). "Effects of drugs on body venous tone, as reflected by mean circulatory filling pressure".
107:
Mean systemic pressure is defined by the stressed volume in the cardiovascular system and the overall systemic capacitance:
83:
using a series of inspiratory holds when a patient is on a mechanical ventilator. It can be used to demonstrate effects of
307:
56:
in the system compared to the capacity of the system), and is influenced by the volume of circulating blood and the
581:
470:"Propofol-induced increase in vascular capacitance is due to inhibition of sympathetic vasoconstrictive activity"
334:
241:
344:
113:
339:
316:
232:
88:
174:
614:
84:
561:
45:
33:
530:
491:
416:
381:
565:
522:
481:
408:
373:
49:
29:
364:
Rothe, CF (Feb 1993). "Mean circulatory filling pressure: its meaning and measurement".
322:
76:
72:
526:
87:
on the venous tone while the circulating blood volume remains constant, or to measure
608:
486:
469:
223:
57:
53:
377:
60:
451:"ICU Physiology in 1000 Words: The Mean Systemic Filling Pressure – Part 2"
412:
553:
534:
495:
420:
385:
92:
41:
17:
168:
Mean systemic pressure is involved in the following calculations:
64:
468:
Hoka, S; Yamaura K; TAkenaka T; Takahashi S (Dec 1998).
79:
once the blood redistributes. It may also be estimated
569:
244:
177:
116:
294:
210:
157:
67:(which determines the capacity of the system).
36:when there is no blood motion. A similar term,
589:
8:
596:
582:
485:
295:{\displaystyle SVR={\frac {MSP-RAP}{CO}}}
257:
243:
176:
129:
115:
356:
158:{\displaystyle MSP={\frac {Vs}{Csys}}}
7:
550:
548:
568:. You can help Knowledge (XXG) by
14:
527:10.1152/ajpheart.1994.266.3.H1242
38:mean circulatory filling pressure
552:
487:10.1097/00000542-199812000-00028
211:{\displaystyle VR\simeq MSP-RAP}
40:, (MCFP) is defined as the mean
26:mean systemic filling pressure
1:
312:MSP = Mean systemic pressure
308:Systemic vascular resistance
228:MSP = Mean systemic pressure
44:that exists in the combined
32:pressure that exists in the
620:Cardiovascular system stubs
434:Boron and Boulpaep (2009).
378:10.1152/jappl.1993.74.2.499
636:
547:
103:Calculations involving MSP
335:Critical closing pressure
28:(MSFP) is defined as the
449:Kenny, JE (June 2017).
345:Central venous pressure
340:Mean arterial pressure
296:
212:
159:
22:mean systemic pressure
562:cardiovascular system
317:Right atrial pressure
297:
233:Right atrial pressure
213:
160:
521:(3 pt 2): H1242–50.
413:10.1093/cvr/26.5.443
242:
175:
114:
89:haemodynamic changes
75:or naturally during
63:in the walls of the
436:Medical Physiology
292:
208:
155:
46:circulatory system
34:circulatory system
577:
576:
290:
153:
627:
598:
591:
584:
556:
549:
539:
538:
506:
500:
499:
489:
480:(6): 1495–1500.
465:
459:
458:
446:
440:
439:
431:
425:
424:
396:
390:
389:
361:
301:
299:
298:
293:
291:
289:
281:
258:
217:
215:
214:
209:
164:
162:
161:
156:
154:
152:
138:
130:
50:pulmonary system
635:
634:
630:
629:
628:
626:
625:
624:
605:
604:
603:
602:
545:
543:
542:
512:
508:
507:
503:
467:
466:
462:
448:
447:
443:
438:(2nd ed.).
433:
432:
428:
401:Cardiovasc. Res
398:
397:
393:
363:
362:
358:
353:
331:
282:
259:
240:
239:
173:
172:
139:
131:
112:
111:
105:
54:volume of blood
12:
11:
5:
633:
631:
623:
622:
617:
607:
606:
601:
600:
593:
586:
578:
575:
574:
557:
541:
540:
510:
501:
474:Anesthesiology
460:
441:
426:
391:
372:(2): 499–509.
366:J Appl Physiol
355:
354:
352:
349:
348:
347:
342:
337:
330:
327:
326:
325:
323:Cardiac output
319:
313:
310:
303:
302:
288:
285:
280:
277:
274:
271:
268:
265:
262:
256:
253:
250:
247:
236:
235:
229:
226:
219:
218:
207:
204:
201:
198:
195:
192:
189:
186:
183:
180:
166:
165:
151:
148:
145:
142:
137:
134:
128:
125:
122:
119:
104:
101:
77:cardiac arrest
73:cardiac arrest
13:
10:
9:
6:
4:
3:
2:
632:
621:
618:
616:
613:
612:
610:
599:
594:
592:
587:
585:
580:
579:
573:
571:
567:
564:article is a
563:
558:
555:
551:
546:
536:
532:
528:
524:
520:
516:
505:
502:
497:
493:
488:
483:
479:
475:
471:
464:
461:
456:
452:
445:
442:
437:
430:
427:
422:
418:
414:
410:
406:
402:
395:
392:
387:
383:
379:
375:
371:
367:
360:
357:
350:
346:
343:
341:
338:
336:
333:
332:
328:
324:
320:
318:
314:
311:
309:
305:
304:
286:
283:
278:
275:
272:
269:
266:
263:
260:
254:
251:
248:
245:
238:
237:
234:
230:
227:
225:
224:Venous return
221:
220:
205:
202:
199:
196:
193:
190:
187:
184:
181:
178:
171:
170:
169:
149:
146:
143:
140:
135:
132:
126:
123:
120:
117:
110:
109:
108:
102:
100:
96:
94:
90:
86:
82:
78:
74:
68:
66:
65:venous system
62:
59:
58:smooth muscle
55:
51:
47:
43:
39:
35:
31:
27:
23:
19:
570:expanding it
559:
544:
518:
515:Am J Physiol
514:
504:
477:
473:
463:
454:
444:
435:
429:
407:(5): 443–8.
404:
400:
394:
369:
365:
359:
167:
106:
97:
80:
69:
37:
25:
21:
15:
93:haemorrhage
615:Physiology
609:Categories
351:References
270:−
197:−
185:≃
24:(MSP) or
329:See also
42:pressure
18:medicine
535:8160829
496:9856725
455:PulmCCM
421:1446314
386:8458763
91:during
81:in vivo
533:
494:
419:
384:
315:RAP =
306:SVR =
231:RAP =
48:&
20:, the
560:This
321:CO =
222:VR =
85:drugs
566:stub
531:PMID
492:PMID
417:PMID
382:PMID
61:tone
30:mean
523:doi
519:266
513:".
511:mcf
482:doi
409:doi
374:doi
16:In
611::
529:.
517:.
490:.
478:89
476:.
472:.
453:.
415:.
405:26
403:.
380:.
370:74
368:.
95:.
597:e
590:t
583:v
572:.
537:.
525::
498:.
484::
457:.
423:.
411::
388:.
376::
287:O
284:C
279:P
276:A
273:R
267:P
264:S
261:M
255:=
252:R
249:V
246:S
206:P
203:A
200:R
194:P
191:S
188:M
182:R
179:V
150:s
147:y
144:s
141:C
136:s
133:V
127:=
124:P
121:S
118:M
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.