46:
33:
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channels, which are potassium channels critical to maintaining normal electrical activities in the heart, but showed no effects on various other potassium channels tested. Inhibitors of sodium channels have also been found in this venom. MeuNaTxa-12 and MeuNaTxa-13 can affect cloned mammalian Nav
376:
contains various neurotoxic proteins that interact specifically with ion channels. A number of unique proteins in this scorpion's venom have been identified, cloned and investigated for clinical applications. For instance,
368:
is not as potent as that of other dangerous buthid species. Victims of stings feel intense pain, hyperemia, swelling and a burning sensation in the affected area, while numbness and itching were also reported in some cases.
1312:
Zhu, Limei; Peigneur, Steve; Gao, Bin; Tytgat, Jan; Zhu, Shunyi (1 September 2013). "Two recombinant α-like scorpion toxins from
Mesobuthus eupeus with differential affinity toward insect and mammalian Na+ channels".
387:, potently inhibits rKv1.1, rKv1.2 and hKv1.3 channels but does not affect rKv1.4, rKv1.5, hKv3.1, rKv4.3, and hERG channels even at high concentrations. In contrast, BeKm-1 specifically inhibits
1397:
Gao, B; Xu, J; Rodriguez Mdel, C; Lanz-Mendoza, H; Hernández-Rivas, R; Du, W; Zhu, S (2010). "Characterization of two linear cationic antimalarial peptides in the scorpion
Mesobuthus eupeus".
411:
effects on bacteria, fungi and yeasts. Furthermore, Meucin-24 and Meucin-25, first identified from genetic sequences expressed in their venom gland, were shown to selectively kill
1611:
1350:"Structural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides"
1624:
768:
1585:
352:
is very rare in this species. They do not dig burrows and prefer using natural spaces and burrows under stones and other objects. They have slender
396:
assays showed that these two toxins have potential to be insecticidal agents, with MeuNaTxa-12 having 5-fold higher toxicity than MeuNaTxa-13.
249:
can reach a size of 4 to 5 centimetres (1.6 to 2.0 in) in length. The entire body is yellow to yellowish brown. The dorsal segments (
427:
parasites, but do not harm mammalian cells. These two venom-derived proteins are therefore attractive candidates for the development of
1236:
Gao, B; Zhu, L; Zhu, S (2011). "A naturally-occurring carboxyl-terminally truncated α-scorpion toxin is a blocker of sodium channels".
1680:
549:
615:
596:
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553:
1144:
Korolkova, YV; Kozlov, SA; Lipkin, AV; Pluzhnikov, KA; Hadley, JK; Filippov, AK; Brown, DA; Angelo, K; et al. (2001).
1106:
Gao, B; Peigneur, S; Tytgat, J; Zhu, S (2010). "A potent potassium channel blocker from
Mesobuthus eupeus scorpion venom".
575:
1520:
1564:
918:
45:
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have a maximum of ten diagonal rows of granules on the fixed finger and eleven on the movable finger. The pedipalp
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719:
383:
759:
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Sanguinetti MC, Tristani-Firouzi M (March 2006). "hERG potassium channels and cardiac arrhythmia".
726:
32:
814:
Cheng-Min Shi; Zu-Shi Huang; Lei Wang; Li-Jun He; Yue-Ping Hua; Liang Leng; De-Xing Zhang (2007).
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820:(Scorpiones, Buthidae) in China: insights from systematic field surveys and predictive models"
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often have longitudinal irregular stripes that are black to dark brown. They exhibit
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261:, the adult females being generally larger than males but have a lower number of
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280:(pincers) are wider than the patella (segment IV). The segments of the
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Omid
Mirshamsi; Alireza Sari; Elahe Elahi; Shidokht Hosseinie (2011).
990:
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67:
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973:(Scorpiones: Buthidae) in China, with description of a new species"
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subtypes rNav1.1, rNav1.2, rNav1.4 and mNav1.6, but not rNav1.5.
1551:
479:
475:
443:
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1471:
229:. It is thought to be the most widely dispersed species of the
1438:(Scorpiones: Buthidae) from Iran: a polytypic species complex"
525:
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so they usually rely on their stings for killing their prey.
1271:
Possani, LD; Becerril, B; Delepierre, M; Tytgat, J (1999).
1348:
Gao, B.; Sherman, P.; Luo, L.; Bowie, J.; Zhu, S. (2008).
1146:"An ERG channel inhibitor from the scorpion Buthus eupeus"
911:(Kock, 1939) from Western Turkey (Scorpiones: Buthidae)"
450:. Its geographical distributions consists of eastern
1480:
1238:
888:
881:(C.L. Koch, 1839) (Scorpiones: Buthidae) in Turkey"
556:. Unsourced material may be challenged and removed.
284:are thick and have eight keels (octocarinate). The
782:
780:
381:, structurally related to BmKTX (α-KTx3.6) from
1139:
1137:
754:
752:
317:of scorpions, the thick-tailed scorpion family
407:. Meucin-13 and Meucin-18 exhibited extensive
816:"Geographical distribution of two species of
769:National Center for Biotechnology Information
265:(16 to 23, as opposed to 22 to 28 in males).
8:
875:Ayşegül Karataş & Ahmet Karataş (2003).
1273:"Scorpion toxins specific for Na+-channels"
1468:
1018:scorpionism in Sanliurfa region of Turkey"
309:in 1839. It is classified under the genus
288:is subglobose with a flat dorsal surface.
31:
20:
1365:
1288:
1161:
1036:
616:Learn how and when to remove this message
870:
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866:
446:or semi-arid habitats with little or no
748:
238:, perhaps even of the family Buthidae.
1025:J. Venom. Anim. Toxins Incl. Trop. Dis
967:Dong Sun & Zhen-Ning Sun (2011).
809:
807:
805:
403:have also been found in the venom of
7:
1578:970b6b2b-0e74-45ec-b2e6-2f437779469f
554:adding citations to reliable sources
372:As in other scorpions, the venom of
1150:The Journal of Biological Chemistry
1012:Ozkan, O.; Kat, I. (Oct 30, 2005).
14:
700:Mesobuthus eupeus philippovitschi
1290:10.1046/j.1432-1327.1999.00625.x
1277:European Journal of Biochemistry
530:
44:
1038:10.1590/S1678-91992005000400008
672:Mesobuthus eupeus mesopotamicus
642:Mesobuthus eupeus barszczewskii
541:needs additional citations for
417:and inhibit the development of
919:Revista Ibérica de Aracnología
340:feed on small insects such as
1:
666:Mesobuthus eupeus kirmanensis
1411:10.1016/j.biochi.2010.01.011
1327:10.1016/j.biochi.2013.05.009
1120:10.1016/j.biochi.2010.08.003
682:Mesobuthus eupeus mongolicus
648:Mesobuthus eupeus bogdoensis
299:were first described by the
214:belonging to the well-known
706:Mesobuthus eupeus thersites
688:Mesobuthus eupeus pachysoma
313:and belongs to the largest
1702:
1250:10.1016/j.bbrc.2011.06.178
694:Mesobuthus eupeus persicus
654:Mesobuthus eupeus haarlovi
636:Mesobuthus eupeus afghanus
321:. Currently, more than 23
1681:Animals described in 1839
1459:10.11646/zootaxa.2929.1.1
1072:(Lesser Asian scorpion) (
183:
175:
156:
149:
41:Scientific classification
39:
30:
23:
905:Teruel, Rolando (2002).
790:(Lesser Asian scorpion)
660:Mesobuthus eupeus iranus
630:Mesobuthus eupeus eupeus
435:Habitat and distribution
221:. Commonly known as the
1068:"Results for organism:"
1163:10.1074/jbc.M005973200
978:Journal of Arachnology
828:Journal of Arachnology
510:, Australia, southern
401:antimicrobial peptides
414:Plasmodium falciparum
223:lesser Asian scorpion
1573:Fauna Europaea (new)
1367:10.1096/fj.08-122317
969:"Notes on the genus
720:Mesobuthus martensii
550:improve this article
1207:10.1038/nature04710
1199:2006Natur.440..463S
727:Hottentotta tamulus
565:"Mesobuthus eupeus"
429:anti-malarial drugs
16:Species of scorpion
1086:UniProt Consortium
708:(C. L. Koch, 1839)
632:(C. L. Koch, 1839)
522:List of subspecies
420:Plasmodium berghei
1686:Scorpions of Asia
1663:
1662:
1638:Open Tree of Life
1512:Mesobuthus eupeus
1482:Mesobuthus eupeus
1474:Taxon identifiers
1436:Mesobuthus eupeus
1354:The FASEB Journal
1076:) " in UniProtKB"
1074:Mesobuthus eupeus
1016:Mesobuthus eupeus
991:10.1636/Ha10-36.1
948:Mesobuthus eupeus
926:(31–VII): 75–76.
909:Mesobuthus eupeus
907:"First Record of
879:Mesobuthus eupeus
799:Taxonomy database
788:Mesobuthus eupeus
762:Mesobuthus eupeus
626:
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600:
440:Mesobuthus eupeus
259:sexual dimorphism
201:Mesobuthus eupeus
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160:Mesobuthus eupeus
25:Mesobuthus eupeus
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1321:(9): 1732–1740.
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442:mostly lives in
329:are recognized.
307:Carl Ludwig Koch
227:mottled scorpion
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1193:(7083): 463–9.
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1156:(13): 9868–76.
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1114:(12): 1847–53.
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956:. 28 June 2006.
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792:(Buthus eupeus)
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1360:(4): 1230–45.
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1283:(2): 287–300.
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1031:(4): 479–491.
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835:(2): 215–226.
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733:Scorpion toxin
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702:(Birula, 1905)
697:
696:(Pocock, 1899)
691:
690:(Birula, 1900)
685:
684:(Birula, 1911)
679:
669:
668:(Birula, 1900)
663:
662:(Birula, 1917)
657:
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650:(Birula, 1896)
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644:(Birula, 1904)
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638:(Pocock, 1889)
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263:pectinal teeth
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142:M. eupeus
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1070:Buthus eupeus
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561:Find sources:
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539:This article
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364:The venom of
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151:Binomial name
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1405:(4): 350–9.
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1276:
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1244:(4): 673–8.
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1089:. Retrieved
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1050:. Retrieved
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1007:
985:(1): 59–75.
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738:Deathstalker
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656:Vachon, 1958
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548:Please help
543:verification
540:
492:Turkmenistan
439:
438:
418:
412:
404:
399:A number of
398:
393:
384:M. martensii
382:
373:
371:
365:
363:
337:
336:
326:
310:
296:
295:
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267:
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245:
233:
226:
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198:
186:
159:
157:
141:
140:
128:
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18:
1599:iNaturalist
1506:Wikispecies
484:Afghanistan
470:, northern
466:, southern
350:Cannibalism
346:cockroaches
242:Description
206:polymorphic
88:Chelicerata
84:Subphylum:
1670:Categories
971:Mesobuthus
818:Mesobuthus
744:References
606:March 2018
576:newspapers
508:Kazakhstan
504:Tajikistan
500:Kyrgyzstan
496:Uzbekistan
474:, eastern
460:Azerbaijan
448:vegetation
323:subspecies
311:Mesobuthus
235:Mesobuthus
190:Koch, 1839
129:Mesobuthus
108:Scorpiones
78:Arthropoda
1399:Biochimie
1315:Biochimie
1108:Biochimie
1081:UniProtKB
1047:1678-9199
932:1576-9518
409:cytolytic
405:M. eupeus
374:M. eupeus
366:M. eupeus
354:pedipalps
344:or small
338:M. eupeus
327:M. eupeus
297:M. eupeus
274:M. eupeus
270:pedipalps
253:) of the
247:M. eupeus
136:Species:
98:Arachnida
64:Kingdom:
58:Eukaryota
1676:Buthidae
1617:11467514
1497:Q3015100
1491:Wikidata
1453:: 1–21.
1419:20097251
1384:13235803
1376:19088182
1335:23743216
1299:10491073
1258:21763288
1215:16554806
1172:11136720
1128:20713119
999:84331221
950:feeding"
849:25067833
713:See also
512:Mongolia
488:Pakistan
342:crickets
319:Buthidae
292:Taxonomy
282:metasoma
255:mesosoma
251:tergites
219:Buthidae
209:scorpion
177:Synonyms
118:Buthidae
114:Family:
74:Phylum:
68:Animalia
54:Domain:
1653:5538346
1591:4553855
1552:3195237
1446:Zootaxa
1195:Bibcode
1091:Sep 18,
1052:Sep 20,
954:YouTube
857:7105197
797:UniProt
678:, 1912)
676:Penther
590:scholar
464:Georgia
456:Armenia
425:malaria
423:, both
394:In vivo
333:Ecology
225:or the
212:species
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170:, 1839)
124:Genus:
104:Order:
94:Class:
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468:Russia
452:Turkey
379:MeuKTX
315:family
301:German
286:telson
278:chelae
216:family
1630:34648
1612:IRMNG
1539:3ZZWF
1441:(PDF)
1380:S2CID
1219:S2CID
1021:(PDF)
995:S2CID
914:(PDF)
884:(PDF)
853:S2CID
845:JSTOR
823:(PDF)
597:JSTOR
583:books
516:China
472:Syria
360:Venom
231:genus
204:is a
1625:NCBI
1586:GBIF
1521:BOLD
1451:2929
1415:PMID
1372:PMID
1331:PMID
1295:PMID
1254:PMID
1211:PMID
1168:PMID
1124:PMID
1093:2011
1054:2011
1043:ISSN
928:ISSN
569:news
480:Iran
476:Iraq
444:arid
389:hERG
268:The
168:Koch
1547:EoL
1534:CoL
1455:doi
1407:doi
1362:doi
1323:doi
1285:doi
1281:264
1246:doi
1242:411
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