1146:, and abortion services. Since the late 1990s, due to rights given by specific policies, the dispensation of emergency contraceptives on issues of religious and moral objections of providing care has extended from doctors, nurses, and hospitals to pharmacies and individual pharmacists. Furthermore, many states have insurance policies that cover contraceptives alongside all other prescription drugs, but may have exemptions for employers or private insurers on religious grounds. Different state legislatures have taken different routes in broadening access to emergency contraceptives. In some states, if a woman has been sexually assaulted, it is mandatory to provide her access to EC. In other states, women have been allowed various amounts of access, including the ability to access EC without a prescription from a physician, creation of policies limiting the ability of pharmacists to deny EC on religious and moral grounds, and creation of policies discouraging pharmacists from denying to fill contraceptive prescriptions. One state even requires all pharmacies to stock and fill every method of contraception. However, other states have restricted access of emergency contraception from state
1158:
cost to the people. In
October 2017, however, the Trump administration made it easier for employers that offer health care plans to exclude contraceptive coverage. The two regulations that allow employers to reject contraceptive coverage are religious and moral objection, but the courts have blocked the enforcement of these regulations. As of today, 29 states require that if insurance covers prescription drugs, it has to provide FDA-approved prescription contraceptive drugs and devices. 10 states prohibit the restriction and delay by insurers or medical management techniques to access contraceptives, and 8 states do not permit refusal on religious or moral grounds by any employers or insurerers. However, 21 states do allow the refusal to comply with the contraceptive coverage mandates, and 14 states prohibit cost sharing for contraceptives.
1167:
religious or moral beliefs, it can affect public health and set a dangerous precedent with respect to "critical, life-saving preventative care". The court denied the claim, stating that all pharmacies, even if the owner has a religious objection, must provide all prescribed medication, including EC. The pharmacy in question tried to appeal the case to the
Supreme Court, but the appeal was rejected, leaving the lower court's ruling in place. Wal-Mart, the third largest U.S. pharmacy chain, refused to carry EC from 1997 to 2006, which shows that accessibility may still be an issue in areas dependent on single pharmacies with no alternatives.
4290:
contribute to efficacy... The pharmacodynamics of ulipristal acetate depends on the timing of administration in the menstrual cycle. Administration in the mid-follicular phase causes inhibition of folliculogenesis and reduction of estradiol concentration. Administration at the time of the luteinizing hormone peak delays follicular rupture by 5 to 9 days. Dosing in the early luteal phase does not significantly delay endometrial maturation but decreases endometrial thickness by 0.6 ± 2.2 mm (mean ± SD).
402:(in the United States) but were withdrawn after more effective dedicated progestin-only (levonorgestrel) emergency contraceptive pills with fewer side effects became available. If other more effective dedicated emergency contraceptive pills (levonorgestrel, ulipristal acetate, or mifepristone) are not available, specific combinations of regular combined oral contraceptive pills can be taken in split doses 12 hours apart (the Yuzpe regimen), effective up to 72 hours after intercourse.
47:
523:, thus delaying menstruation by a few days. Mifepristone, if taken before ovulation, may delay ovulation by 3–4 days (delayed ovulation may result in a delayed menstruation). These disruptions only occur in the cycle in which ECPs were taken; subsequent cycle length is not significantly affected. If a woman's menstrual period is delayed by two weeks or more, it is advised that she take a
375:(also known as RU-486) is available in five countries as a low-dose or mid-dose emergency contraceptive tablet, effective up to 120 hours after intercourse. Low-dose mifepristone ECPs are available by prescription in Armenia, Russia, Ukraine, and Vietnam and from a pharmacist without a prescription in China. Mid-dose mifepristone ECPs are available by prescription in China and Vietnam.
3821:
effective than the single 1.5 mg dose of levonorgestrel when used within 72 hours after sexual intercourse and even between 72 h and 120h. ... Progesterone receptor modulators like ulipristal acetate and mifepristone suppress ovarian follicular growth and also delay endometrial maturation, manifested in a delay in menstruation after treatment. Ovulation can be temporarily postponed.
665:(AAP) stated: "Despite multiple studies showing no increased risk behaviour and evidence that hormonal emergency contraception will not disrupt an established pregnancy, public and medical discourse reflects that personal values of physicians and pharmacists continue to affect emergency-contraception access, particularly for adolescents."
3811:
dose of levonorgesterel administered postcoitally once fertilization had occurred. The evidence indicates that a postfertilization effect does not contribute to the efficacy of emergency contraception. Clinicians, pharmacists, and patients can be reassured that treatment with emergency contraception is not an abortifacient.
429:... these numbers do not translate into a pregnancy rate of 25 percent. Rather, they mean that if 1,000 women have unprotected intercourse in the middle two weeks of their menstrual cycles, approximately 80 will become pregnant. Use of emergency contraceptive pills would reduce this number by 75 percent, to 20 women.
357:(OTC) in many countries (e.g. Australia, Bangladesh, Bulgaria, Canada, Cyprus, Czech Republic, Denmark, Estonia, India, Malta, Netherlands, Norway, Portugal, Romania, Slovakia, South Africa, Sweden, United States), from a pharmacist without a prescription, and available with a prescription in some other countries.
4722:"Since the United Kingdom approved emergency contraceptive pills in 1984, more than 4 million prescriptions have been recorded. However, the actual use is much greater because providers have found it less expensive to provide tablets of identical drugs taken from products packaged as combined oral contraceptives."
815:
and had been withdrawn from marketing in New
Zealand in 1997 to prevent it being sold over-the-counter. Regular combined oral contraceptive pills (which were less expensive and more widely available) were more commonly used for the Yuzpe regimen even in countries where dedicated products were available.
4289:
When taken immediately before ovulation is to occur, ella postpones follicular rupture. The likely primary mechanism of action of ulipristal acetate for emergency contraception is therefore inhibition or delay of ovulation; however, alterations to the endometrium that may affect implantation may also
3952:
The precise mode of action of
Levonelle One Step is not known. At the recommended regimen, levonorgestrel is thought to work mainly by preventing ovulation and fertilisation if intercourse has taken place in the preovulatory phase when the likelihood of fertilisation is the highest. It may also cause
1411:
To make an informed choice, women must know that ECPs—like the birth control pill, patch, ring, shot, and implant, and even like breastfeeding—prevent pregnancy primarily by delaying or inhibiting ovulation and inhibiting fertilization, but may at times inhibit implantation of a fertilized egg in the
3810:
There is strong evidence that treatment with emergency contraception acts primarily by preventing or delaying ovulation and by preventing fertilization. Studies have indicated that emergency contraception does not prevent implantation. Experiments in monkeys and rats could detect no effect of a high
1406:
When used as a regular or emergency method of contraception, copper-releasing IUCs act primarily to prevent fertilization. Emergency insertion of a copper IUC is significantly more effective than the use of ECPs, reducing the risk of pregnancy following unprotected intercourse by more than 99%. This
971:
a manufacturer obtained an approved ANDA that provided patient labeling and special packaging as set out in a FDA final rule published in
February 1975. To discourage off-label use of DES as a postcoital contraceptive, in February 1975 the FDA ordered DES 25 mg (and higher) tablets removed from
747:
is to prevent fertilization by inhibition or delay of ovulation. One clinical study found that post-ovulatory administration of ulipristal acetate altered the endometrium, but whether the changes would inhibit implantation is unknown. The
European EMA-approved labels for ulipristal acetate emergency
622:
Insertion of an IUD is more effective than the use of emergency contraceptive pills – pregnancy rates when used as emergency contraception are the same as with normal IUD use. Unlike emergency contraceptive pills, which work by delaying ovulation, the copper-T IUD works by interfering
413:
of certain brands of regular combined oral contraceptive pills in 1997. As of 2014, there are 26 brands of regular combined oral contraceptive pills containing levonorgestrel or norgestrel available in the United States that can be used in the emergency contraceptive Yuzpe regimen, when none of
3129:
LNG ECPs do not interrupt an established pregnancy or harm a developing embryo. The evidence available to date shows that LNG ECP use does not prevent a fertilized egg from attaching to the uterine lining. The primary mechanism of action is to stop or disrupt ovulation; LNG ECP use may also prevent
984:
was sent to all U.S. physicians and pharmacists which said: "FDA has not yet given approval for any manufacturer to market DES as a postcoital contraceptive. The Agency, however, will approve this indication for emergency situations such as rape or incest if a manufacturer provides patient labeling
809:
The Yuzpe regimen became the standard course of treatment for postcoital contraception in many countries in the 1980s. The first prescription-only combined estrogen-progestin dedicated product, Schering PC4 (ethinylestradiol and norgestrel), was approved in the UK in
January 1984 and first marketed
448:
For 10 mg of mifepristone taken up to 120 hours (5 days) after intercourse, the combined estimate from three trials was an effectiveness of 83%. A review found that a moderate dose of mifepristone is better than LNG or Yuzpe, with delayed return of menstruation being the main adverse effect of
4263:
Ulipristal acetate is an orally-active synthetic selective progesterone receptor modulator which acts via high-affinity binding to the human progesterone receptor. The primary mechanism of action is inhibition or delay of ovulation. Pharmacodynamic data show that even when taken immediately before
3864:
It is believed that the main mechanism of action of high-dose progestin emergency contraception is inhibition of ovulation, but other mechanisms may be involved... Taken together, these data are highly supportive of the concept that levonorgestrel emergency contraception has little or no effect on
3820:
Ulipristal
Acetate. Ulipristal acetate (ellaOne) has similar biologic effects as mifepristone and is approved for emergency contraception in Europe and is expected to become available in the U.S.in a single oral dose of 30 mg. Randomized trials demonstrated that ulipristal acetate is slightly more
2556:
Copper-bearing intrauterine device (Cu-IUD). Copper is toxic to the ovum and sperm and thus the copper-bearing intrauterine device (Cu-IUD) is effective immediately after insertion and works primarily by inhibiting fertilisation. A systematic review on mechanisms of action of IUDs showed that both
857:
Early studies of emergency contraceptives did not attempt to calculate a failure rate; they simply reported the number of women who became pregnant after using an emergency contraceptive. Since 1980, clinical trials of emergency contraception have first calculated probable pregnancies in the study
814:
dedicated prescription-only combined products had been approved in only 9 countries: the UK (Schering PC4), New
Zealand (Schering PC4), South Africa (E-Gen-C), Germany (Tetragynon), Switzerland (Tetragynon), Denmark (Tetragynon), Norway (Tetragynon), Sweden (Tetragynon) and Finland (Neoprimavlar);
673:
Beginning in the 1960s, women who had been sexually assaulted were offered diethylstilbestrol (DES). Currently, the standard of care is to offer ulipristal or prompt placement of a copper IUD which is the most effective form of EC. However, adherence to these best practices varies by the emergency
452:
HRA Pharma changed its packaging information for
Norlevo (levonorgestrel 1.5 mg, which is identical to many other EHCs) in November 2013 warning that according to studies the drug loses effectiveness in women who weigh more than 75 kg (165 lb) and is completely ineffective for women
352:
Progestin-only emergency contraceptive pills contain levonorgestrel, either as a single tablet (or historically, as a split dose of two tablets taken 12 hours apart), effective up to 72 hours after intercourse. Progestin-only ECPs are sold under many different brand names. Progestin-only
3871:
Ulipristal, also known as CDB-2914, has been studied as an emergency contraceptive pill... In 2009, European regulatory approval was granted for a 30-mg tablet of ulipristal (under the brand name of EllaOne) as an emergency contraceptive pill for use up to 5 days after unprotected intercourse. An
3825:
Another method of emergency contraception is the insertion of a copper IUD, anytime during the preovulatory phase of the menstrual cycle and up to 5 days after ovulation. The failure rate (in a small number of studies) is very low, 0.1%. This method definitely prevents implantation, but it is not
1157:
of 2010 has guaranteed coverage of contraceptives, applying to most private health plans nationwide. The provision has also specifically required coverage for 18 methods of contraception used by women, related counselling and services, and requires the coverage provided not to be an out-of-pocket
1166:
challenged Washington state regulations on providing all lawfully prescribed pharmaceuticals, including EC. They were challenging Washington state regulations on providing all lawfully prescribed pharmaceuticals. Courts have been warned that if pharmacists are allowed to deny EC prescriptions on
1161:
Emergency contraceptives are the most common prescription drug denied due to of religious or moral beliefs. There have been cases where hormones, drugs and devices used to treat human immunodeficiency virus and diabetic medication have also been denied. This topic continues to be fought upon on
3979:
The precise mode of action of Norlevo 1.5 mg is not known. At the used regimen, levonorgestrel is believed to suppress ovulation thus preventing fertilization if the intercourse has taken place in the preovulatory phase when the likelihood of fertilization is the highest. It could also prevent
437:
In 1999, a meta-analysis of eight studies of the combined (Yuzpe) regimen concluded that the best point estimate of effectiveness was 74%. A 2003 analysis of two of the largest combined (Yuzpe) regimen studies, using a different calculation method, found effectiveness estimates of 47% and 53%.
4001:
Emergency contraceptive pills are not effective if a woman is already pregnant. Plan B One-Step is believed to act as an emergency contraceptive principally by preventing ovulation or fertilization (by altering tubal transport of sperm and/or ova). In addition, it may inhibit implantation (by
707:
changes that discourage implantation. Daily use of regular oral contraceptive pills can alter the endometrium (although this has not been proven to interfere with implantation), but the isolated use of a levonorgestrel emergency contraceptive pill does not have time to alter the endometrium.
3817:
Mifepristone. In randomized trials, 10 mg mifepristone was as effective as 25, 50, or 600 mg. preventing about 80–85% of expected pregnancies (the same efficacy and side effects as with the levonorgestrel method), with a slight decrease in efficacy when treatment was delayed to 5 days after
848:
In 2020, Japan announced it would consider easing regulations on the sale of emergency contraceptive pills without a prescription. Non-profit groups submitted a petition to the health ministry calling for prescription-free access to the pill. They had collected more than 100,000 signatures.
878:
Calculation of effectiveness, and particularly the denominator of the fraction, involves many assumptions that are difficult to validate. The risk of pregnancy for women requesting ECPs appears to be lower than assumed in the estimates of ECP efficacy, which are consequently likely to be
4049:• The fact that LNG ECPs have no demonstrated effect on implantation explains why they are not 100% effective in preventing pregnancy and are less effective the later they are taken. Women should be given a clear message that LNG ECPs are more effective the sooner they are taken.
1041:
On March 23, 2009, a US judge ordered the FDA to allow 17-year-olds to acquire Plan B without a prescription. This now changes the August 24, 2006, ruling and Plan B is now available "behind the counter" for men and women. There is a prescription method available for girls under
2244:
WHO Task Force on Postovulatory Methods of Fertility Regulation (August 1998). "Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Task Force on Postovulatory Methods of Fertility Regulation".
826:, "played a pioneering role in emergency contraception" by "confirming the effectiveness of levonorgestrel." After the WHO conducted a large trial comparing Yuzpe and levonorgestrel in 1998, combined estrogen-progestin products were gradually withdrawn from some markets (
345:. Combined estrogen and progestin pills are no longer recommended as dedicated emergency contraceptive pills (because this regimen is less effective and caused more nausea), but certain regular combined oral contraceptive pills (taken 2–5 at a time in what was called "the
2553:
In 2002, a judicial review ruled that pregnancy begins at implantation, not fertilisation. The possible mechanisms of action should be explained to the patient as some methods may not be acceptable, depending on individual beliefs about the onset of pregnancy and
433:
The progestin-only regimen (using levonorgestrel) has an 89% effectiveness. As of 2006, the labeling on the U.S. brand Plan B explained this effectiveness rate by stating, "Seven out of every eight women who would have gotten pregnant will not become pregnant."
3826:
suitable for women who are not candidates for intrauterine contraception, e.g., multiple sexual partners or a rape victim. The use of a copper IUD for emergency contraception is expensive, but not if it is retained as an ongoing method of contraception.
674:
department. Before these EC options were available (in 1996), pregnancy rates among females of child-bearing age who had been raped were around 5%. Although EC is recommended following sexual assault, room for improvement in clinical practice remains.
261:
measure taken to reduce the risk of pregnancy following unprotected sexual intercourse or when other regular contraceptive measures have not worked properly or have not been used correctly. It is intended to be used occasionally and is not the same as
623:
with sperm motility. Therefore, the copper IUD is equally effective as emergency contraception at all weight ranges. IUDs may be left in place following the subsequent menstruation to provide ongoing contraception for as long as desired (12+ years).
944:
In September 1973, the FDA published a proposed rule specifying patient labeling and special packaging requirements for any manufacturer seeking FDA approval to market DES as a postcoital contraceptive, inviting manufacturers to submit abbreviated
682:
The primary mechanism of action of progestogen-only emergency contraceptive pills is to prevent fertilization by inhibition of ovulation. The best available evidence is that they do not have any post-fertilization effects such as the prevention of
1030:
On August 24, 2006, the FDA approved nonprescription behind-the-counter access to Plan B from pharmacies staffed by a licensed pharmacist for women 18 or older; a prescription-only form of Plan B was made available for younger females aged 17 and
657:
Making ECPs more widely available does not increase sexual risk-taking. While they are effective for individuals who use them in a timely fashion, the availability of EC pills does not appear to decrease abortion rates at the population level.
1414:
ECPs do not cause abortion or harm an established pregnancy. Pregnancy begins with implantation according to medical authorities such as the US FDA, the National Institutes of Health and the American College of Obstetricians and Gynecologists
861:
Placebo-controlled trials that could give a precise measure of the pregnancy rate without treatment would be unethical, so the effectiveness percentage is based on estimated pregnancy rates. These are currently estimated using variants of the
1009:
saying it had concluded that the Yuzpe regimen was safe and effective for off-label use as postcoital EC, was prepared to accept NDAs for COCPs labeled as ECPs, and listed 6 then available COCPs (there are now 22) that could be used as
249:(IUDs) – usually used as a primary contraceptive method – are sometimes used as the most effective form of emergency contraception. However, the use of IUDs for emergency contraception is relatively rare.
932:
was sent to all U.S. physicians and pharmacists that said the FDA had approved, under restricted conditions, postcoital contraceptive use of DES. (In February 1975, the FDA Commissioner testified that the only error in the May 1973
4923:
Espinós JJ, Rodríguez-Espinosa J, Senosiain R, Aura M, Vanrell C, Gispert M, et al. (October 1999). "The role of matching menstrual data with hormonal measurements in evaluating effectiveness of postcoital contraception".
549:(AAP) and experts on emergency contraception have concluded that progestin-only ECPs are preferable to combined ECPs containing estrogen for all women, and particularly those with a history of blood clots, stroke, or migraine.
956:, the largest U.S. manufacturer of DES, discontinued its DES 25 mg tablets and in March 1974 sent a letter to all U.S. physicians and pharmacists telling them it did not recommend use of DES as a postcoital contraceptive.
511:. Side effects generally resolve within 24 hours, although temporary disruption of the menstrual cycle is commonly experienced. If taken before ovulation, the high doses of progestogen in levonorgestrel treatments may induce
715:(FIGO) issued a statement that: "review of the evidence suggests that LNG ECPs cannot prevent implantation of a fertilized egg. Language on implantation should not be included in LNG ECP product labeling." In June 2012, a
1134:
allowed women to have parental control over childrearing, including the use of contraception for reproductive autonomy. After this, women became more informed about contraceptives and began requesting them more often.
4152:
483:
is much less common and unusual with levonorgestrel-only ECPs (5.6% of levonorgestrel-only users vs 18.8% of 979 Yuzpe regimen users in 1998 WHO trial; 1.4% of 2,720 levonorgestrel-only users in the 2002 WHO trial).
2361:
von Hertzen H, Piaggio G, Ding J, Chen J, Song S, Bártfai G, et al. (December 2002). "Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial".
1909:
966:
In February 1975, the FDA said it had not yet approved DES as a postcoital contraceptive, but would after March 8, 1975, permit marketing of DES for that indication in emergency situations such as rape or incest
3867:
Intrauterine insertion of a copper IUD within 5 to 10 days of midcycle coitus is a very effective method of preventing continuation of the pregnancy... The LNG-IUS should not be used for emergency contraception.
976:
BE USED AS A POSTCOITAL CONTRACEPTIVE" in block capital letters on the first line of the physician prescribing information package insert and in a prominent and conspicuous location of the container and carton
4018:
787:
monkeys, respectively. A few different drugs were studied, with a focus on high-dose estrogens, and it was originally hoped that postcoital contraception would prove viable as an ongoing contraceptive method.
5042:
Regulation of diethylstilbestrol (DES), 1975: Joint Hearing before the Subcommittee on Health and the Subcommittee on Administrative Practice and Procedure, 94th Congress, 1st Session on S. 963, February 27,
1076:
On June 10, 2013, the Obama administration ceased trying to block over-the-counter availability of the pill. With this reversal it means that any person will be able to purchase the Plan B One-Step without a
518:
One study found that about half of women who used levonorgestrel ECPs experienced bleeding within 7 days of taking the pills. If levonorgestrel is taken after ovulation, it may increase the length of the
763:. The very high effectiveness of copper-releasing IUDs as emergency contraceptives implies that they must also prevent some pregnancies by post-fertilization effects such as prevention of implantation.
1412:
endometrium. However, women should also be informed that the best available evidence indicates that ECPs prevent pregnancy by mechanisms that do not involve interference with post-fertilization events.
534:
in terms of safety, as there is no known harm to the woman, the course of her pregnancy, or the fetus if progestin-only or combined emergency contraception pills are accidentally used, but EC is not
425:
The effectiveness of emergency contraception is expressed as a percentage reduction in pregnancy rate for a single use of EC. Using an example of "75% effective", the effectiveness calculation thus:
4073:
The F.D.A. now acknowledges that the emerging data suggest the morning-after pill, often called Plan B, does not inhibit implantation. It should remove that unsupported suggestion from the label.
1013:
On September 1, 1998, the FDA approved the prescription Yuzpe regimen Preven Emergency Contraception Kit (which contained a urine pregnancy test and 4 COCPs). Preven was discontinued in May 2004.
748:
contraceptive pills do not mention an effect on implantation, but the U.S. FDA-approved label says: "alterations to the endometrium that may affect implantation may also contribute to efficacy."
325:) pills. Progestin-only and anti-progestin pills are available as specifically packaged pills for use as emergency contraceptive pills. Emergency contraceptive pills originally contained higher
949:(ANDAs) for that indication, and notifying manufacturers that the FDA intended to order the withdrawal of DES 25 mg tablets (which were being used off-label as postcoital contraceptives).
1575:
Vlad S, Boucoiran I, St-Pierre ÉR, Ferreira E (June 2022). "Mifepristone-Misoprostol Use for Second- and Third-Trimester Medical Termination of Pregnancy in a Canadian Tertiary Care Centre".
5549:
635:
pills was marketed as an ongoing method of postcoital contraception. However, with typical use, failure rates are expected to be higher than with the use of other birth control methods.
4240:
360:
The antiprogestin ulipristal acetate is available as a micronized emergency contraceptive tablet, effective up to 120 hours after intercourse. Ulipristal acetate ECPs developed by
3891:"How the morning-after pill works (interview with Kristina Gemzell-Danielsson, MD, Professor and Chair, Division of Obstetrics and Gynecology, Karolinska Institute, Stockholm, Sweden)"
1038:
announced that its subsidiary, Duramed Pharmaceuticals, had initiated shipment of dual-label Plan B OTC/Rx and it would be available in pharmacies across the U.S. by mid-November 2006.
488:
are not routinely recommended with levonorgestrel-only ECPs. If a woman vomits within 2 hours of taking a levonorgestrel-only ECP, she should take a further dose as soon as possible.
4108:
649:
is torn during sex. However, for women facing reproductive coercion, who are not able to use regular birth control, repeated use of EC pills may be the most viable option available.
985:
and special packaging. To discourage 'morning after' use of DES without patient labeling, FDA has removed from the market the 25 mg tablets of DES, formerly used for this purpose."
879:
overestimates. Yet, precise estimates of efficacy may not be highly relevant to many women who have had unprotected intercourse, since ECPs are often the only available treatment.
4014:
1116:
resulted in the U.S. Supreme Court's 1973 ruling to legalize abortion, both Federal and State laws were created to allow medical professionals and institutions the right to deny
712:
5485:
4047:• Review of the evidence suggests that LNG ECPs cannot prevent the implantation of a fertilized egg. Language on implantation should not be included in LNG ECP product labeling.
1420:
One study has demonstrated that UP can delay ovulation.... Another study found that UPA altered the endometrium, but whether this change would inhibit implantation is unknown.
721:
editorial called on the FDA to remove from the label the unsupported suggestion that levonorgestrel emergency contraceptive pills inhibit implantation. In November 2013, the
457:, the statement was deleted from the leaflet. The agency communicated that levonorgestrel is safe and effective method of emergency contraception, regardless of body weight.
441:
For both the progestin-only and Yuzpe regimens, the effectiveness of emergency contraception is highest when taken within 12 hours of intercourse and declines over time. The
1913:
6237:
4087:"New birth control label counters lawsuit claim; European authorities found that a drug like Plan B One-Step cannot prevent fertilized eggs from implanting in the womb"
5743:
3865:
postovulation events but is highly effective when taken before ovulation. Levonorgestrel emergency contraception does not affect implantation and is not abortifacient.
3525:
3484:
1150:
family planning eligibility expansions or contraceptive coverage mandates, or by allowing the refusal of providing contraceptive services by healthcare professionals.
619:
was as effective at emergency contraception as the copper IUD, though it is not offered by clinicians at the moment due to the lack of research done into the subject.
2574:
5262:
4022:
818:
Over time, interest in progestin-only treatments increased. The Special Program on Human Reproduction (HRP), an international organization whose members include the
5803:
5437:
4133:
4051:• LNG ECPs do not interrupt a pregnancy (by any definition of the beginning of pregnancy). However, LNG ECPs can prevent abortions by reducing unwanted pregnancies.
1965:"Status of Emergency Contraceptives in Europe One Year after the European Medicines Agency's Recommendation to Switch Ulipristal Acetate to Non-Prescription Status"
1087:
972:
the market and ordered the labeling of lower doses (5 mg and lower) of DES still approved for other indications be changed to state: "THIS DRUG PRODUCT SHOULD
4156:
3962:
2559:
Levonorgestrel (LNG). The precise mode of action of levonorgestrel (LNG) is incompletely understood but it is thought to work primarily by inhibition of ovulation.
5951:
3843:
Jensen JT, Mishell Jr DR (2012). "Family planning: contraception, sterilization, and pregnancy termination". In Lentz GM, Lobo RA, Gershenson DM, Katz VL (eds.).
3708:
Holmes MM, Resnick HS, Kilpatrick DG, Best CL (August 1996). "Rape-related pregnancy: estimates and descriptive characteristics from a national sample of women".
3365:
4226:
in endometrial thickness from a baseline of 10.2 ± 3.2 mm to 11.5 ± 4.1 mm with placebo administration) which the authors hypothesized could hamper implantation.
2607:
810:
in October 1984. Schering introduced a second prescription-only combined product, Tetragynon (ethinylestradiol and levonorgestrel) in Germany in 1985. By 1997,
2202:
Trussell J, Ellertson C, von Hertzen H, Bigrigg A, Webb A, Evans M, et al. (April 2003). "Estimating the effectiveness of emergency contraceptive pills".
858:
group if no treatment were given. The effectiveness is calculated by dividing observed pregnancies by the estimated number of pregnancies without treatment.
6112:
2480:
2405:
Piaggio G, Heng Z, von Hertzen H, Bilian X, Linan C (December 2003). "Combined estimates of effectiveness of mifepristone 10 mg in emergency contraception".
2139:
5673:
Brief of American Academy of Pediatrics in Support of Respondents, Zubik v Burwell (Nos. 14–1418, 14–1453, 14–1505, 15–35, 15–105, 15–119, and 15-191) 2016.
2664:
Raymond EG, Goldberg A, Trussell J, Hays M, Roach E, Taylor D (April 2006). "Bleeding patterns after use of levonorgestrel emergency contraceptive pills".
2557:
pre- and postfertilisation effects contribute to efficacy. If fertilisation has already occurred, it is accepted that there is an anti-implantation effect,
913:
870:) must be excluded from such calculations. Even for women included in the calculation, the limitations of calendar methods of fertility determination have
645:
ECPs are generally recommended for backup or "emergency" use – for example, if a woman has forgotten to take a birth control pill or when a
575:
by preventing pregnancies and there is no increase in the relative risk of ectopic pregnancy in women who become pregnant after using progestin-only ECPs.
802:
in 1974; progestin-only postcoital contraception was investigated (1975); and the copper IUD was first studied for use as emergency contraception (1975).
4218:
Post-ovulatory early luteal phase administration of 10–100 mg of ulipristal acetate resulted in a statistically significant dose-dependent 0.6 ± 2.2 mm
3869:
A study by the WHO reported that use of a single tablet of 10 mg of mifepristone was an effective emergency contraceptive with a pregnancy rate of 1.2%.
5761:
5683:
5167:
FDA (February 5, 1975). "Certain estrogens for oral use or parenteral use. Drugs for human use; drug efficacy study implementation; follow-up notice".
3916:
2319:
5984:
5714:
1446:
736:
4618:
4592:
3928:
732:
Progestogen-only emergency contraceptive does not appear to affect the function of the fallopian tubes or increase the rate of ectopic pregnancies.
1093:
1069:
one-pill levonorgestrel emergency contraceptives and all two-pill levonorgestrel emergency contraceptives will remain restricted to sale from a
4247:
1181:
3192:
231:
There are different forms of EC. Emergency contraceptive pills (ECPs), sometimes simply referred to as emergency contraceptives (ECs), or the
6230:
6004:
5776:
5277:
5245:
5214:
5132:
4302:
3852:
3794:
2986:
2619:
2586:
2167:
Trussell J, Rodríguez G, Ellertson C (March 1999). "Updated estimates of the effectiveness of the Yuzpe regimen of emergency contraception".
1530:
1376:
842:
in France) in favor of progestin-only EC, although prescription-only dedicated Yuzpe regimen products are still available in some countries.
5524:
3236:"Science Update: Hormonal IUD as effective as a copper IUD at emergency contraception and with less discomfort, NICHD-funded study suggests"
6149:
5857:
615:. Some studies have found it to be effective up to 10 days after unprotected intercourse to prevent pregnancy. A 2021 study found that the
4664:
1427:
Early treatment with ECPs containing only the progestin levonorgestrel has been shown to impair the ovulatory process and luteal function.
422:
Ulipristal acetate, and mid-dose mifepristone are both more effective than levonorgestrel, which is more effective than the Yuzpe method.
5650:
3116:
UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP) (March 25, 2010).
1941:
6641:
5827:
5796:
4845:
Dixon GW, Schlesselman JJ, Ory HW, Blye RP (September 1980). "Ethinyl estradiol and conjugated estrogens as postcoital contraceptives".
1367:
Trussell J, Schwarz EB (2011). "Emergency contraception". In Hatcher RA, Trussell J, Nelson AL, Cates W Jr, Kowal D, Policar MS (eds.).
2132:
3341:
1488:
1434:
Several clinical studies have shown that combined ECPs containing ethinylestradiol and levonorgestrel can inhibit or delay ovulation.
5961:
2458:
1873:. Princeton: Office of Population Research at Princeton University, Association of Reproductive Health Professionals. Archived from
1783:. Princeton: Office of Population Research at Princeton University, Association of Reproductive Health Professionals. Archived from
1407:
very high level of effectiveness implies that emergency insertion of a copper IUC must prevent some pregnancies after fertilization.
364:
are available over the counter in Europe and by prescription in over 50 countries under the brand names ellaOne, ella (marketed by
5378:
5346:
3472:
3415:
963:, ever submitted (in January 1974) an ANDA for use of DES as an emergency postcoital contraceptive, and the FDA never approved it.
491:
Other common side effects (each reported by less than 20% of levonorgestrel-only users in both the 1998 and 2002 WHO trials) were
6223:
5946:
4799:
3953:
endometrial changes that discourage implantation. Levonelle One Step is not effective once the process of implantation has begun.
1669:"Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions"
700:
342:
200:
Yuzpe regimen (combined estrogen/progestin pills at higher doses) is no longer recommended unless other options are not available
4086:
2440:
599:) may reduce the effectiveness of ECP, and a larger dose may be required, especially in women who weigh more than 165 lbs.
6636:
5847:
3947:
899:
568:
are conditions where the advantages of using emergency contraceptive pills generally outweigh the theoretical or proven risks.
293:
Emergency contraceptive pills (ECPs) are sometimes referred to as emergency hormonal contraception (EHC). They are taken after
4694:
3743:
Stewart FH, Trussell J (November 2000). "Prevention of pregnancy resulting from rape: a neglected preventive health measure".
1867:
806:
was tested in the early 1980s in the hopes that it would have fewer side effects than Yuzpe, but was found to be ineffective.
5976:
5789:
3509:
1777:
1667:
Cumpston M, Li T, Page MJ, Chandler J, Welch VA, Higgins JP, Thomas J, et al. (Cochrane Editorial Unit) (October 2019).
1046:
991:
DES is no longer commercially available in the U.S.; Eli Lilly, the last U.S. manufacturer, ceased production in spring 1997.
662:
639:
546:
145:
2592:
5308:
5078:
FDA (February 26, 1975). "Estrogens for oral or parenteral use. Drugs for human use; drug efficacy study; amended notice".
3379:
Gottardi G, Spreafico A, de Orchi L (December 1986). "The postcoital IUD as an effective continuing contraceptive method".
309:
A variety of emergency contraceptive pills are available, including combined estrogen and progestin pills; progestin-only (
5966:
5735:
5283:
3517:
924:
In May 1973, in an attempt to restrict off-label use of DES as a postcoital contraceptive to emergency situations such as
5441:
4137:
4124:
NorLevo works by stopping your ovaries from releasing an egg. It cannot stop a fertilized egg from attaching to the womb.
3966:
266:. Emergency contraception is offered to women who do not wish to conceive but have had unprotected sex on any day of the
5415:
5383:
5316:
5205:
Hatcher, Robert A.; Stewart, Gary K.; Stewart, Felicia; Guest, Felicia; Schwartz, David W.; Jones, Stephanie A. (1980).
4672:
3785:
Speroff L, Darney P (2011). "Special uses of oral contraception: emergency contraception, the progestin-only minipill".
688:
565:
406:
5097:
FDA (September 26, 1973). "Certain estrogens for oral use. Notice of withdrawal of approval of new drug applications".
2091:
6560:
4064:
2625:
684:
5749:
2941:
5620:
3008:
2639:
278:. Emergency contraception measures include tablets taken by mouth or the insertion of a copper intrauterine device.
6171:
6136:
5578:
2575:"Question 20. What can a woman do to prevent nausea and vomiting when taking emergency contraceptive pills (ECPs)?"
561:
2476:
921:, led to off-label use of DES as a postcoital contraceptive becoming prevalent at many university health services.
6049:
5994:
5503:"FDA approves Plan B One-Step emergency contraceptive without a prescription for women 15 years of age and older"
2315:
1262:"The efficacy of intrauterine devices for emergency contraception: a systematic review of 35 years of experience"
1163:
823:
722:
692:
545:(WHO) lists no medical condition for which the risks of emergency contraceptive pills outweigh the benefits. The
542:
454:
442:
4880:
Trussell J, Ellertson C, Stewart F (1996). "The effectiveness of the Yuzpe regimen of emergency contraception".
6421:
6392:
6275:
5902:
5550:"Emergency contraception sales fall by more than 50% as pandemic causes 'disruption' to sexual health services"
4712:
FDA (February 25, 1997). "Certain combined oral contraceptives for use as postcoital emergency contraception".
2008:
1139:
1049:' Plan B One-Step for sale without a prescription to anyone age 15 or over who can show proof of age such as a
988:
In the 1980s, off-label use of the Yuzpe regimen superseded off-label use of DES for postcoital contraception.
638:
Like all hormonal methods, postcoital high-dose progestin-only oral contraceptive pills do not protect against
611:(IUD) which is generally recommended up to 5 days after unprotected intercourse or up to 5 days after probable
538:
for a woman with a known or suspected pregnancy because it is not effective in women who are already pregnant.
2561:
Ulipristal acetate (UPA). UPA's primary mechanism of action is thought to be inhibition or delay of ovulation.
159:
ECP may disrupt next menstrual period by a couple of days. IUDs may make menstruation heavier and more painful
4281:
4180:"Endometrial effects of a single early luteal dose of the selective progesterone receptor modulator CDB-2914"
4019:"Mechanism of action: How do levonorgestrel-only emergency contraceptive pills (LNG ECPs) prevent pregnancy?"
2335:
6064:
5230:
Hatcher, Robert A.; Stewart, Gary K.; Stewart, Felicia; Guest, Felicia; Josephs, Nancy; Dale, Janet (1982).
3890:
1130:
780:
5711:
5502:
866:. Women with irregular cycles for any reason (including recent hormone use such as oral contraceptives and
445:(WHO) suggested that reasonable effectiveness may continue for up to 120 hours (5 days) after intercourse.
6591:
6387:
6270:
6246:
6144:
5936:
5927:
5891:
5599:
1309:
Leung VW, Levine M, Soon JA (February 2010). "Mechanisms of action of hormonal emergency contraceptives".
918:
871:
783:, reported the successful use of oral high-dose estrogen pills as post-coital contraceptives in women and
4596:
4264:
ovulation is scheduled to occur, ulipristal acetate is able to postpone follicular rupture in some women.
3993:
6550:
6026:
5989:
5883:
953:
883:
In 1999, hormonal assay was suggested as a more accurate method of estimating fertility for EC studies.
535:
354:
334:
5727:
4528:"Copper IUD, inserted after coitus averts pregnancy and provides continuing contraceptive protection".
4665:"Medical Officer Review of NDA 21,045: Levonorgestrel 0.75 mg tablets (2) for Emergency Contraception"
1525:(80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. pp. 838–839.
1096:
was reported to have caused "significant disruption" to contraceptive services in the United Kingdom.
6054:
5739:
4474:
Yuzpe AA, Thurlow HJ, Ramzy I, Leyshon JI (August 1974). "Post coital contraception--A pilot study".
3521:
3480:
1035:
946:
776:
584:
4619:"Effect of various 6-hydroxydopamine treatments during development on growth and ingestive behavior"
6516:
6506:
6372:
6318:
6313:
6179:
6154:
5956:
5868:
5056:
FDA (September 26, 1973). "Diethylstilbestrol. Use as postcoital contraceptive; patient labeling".
4045:• Inhibition or delay of ovulation is LNG ECPs principal and possibly the only mechanism of action.
3211:
2971:
2608:"Question 21. What can a woman do if she vomits after taking emergency contraceptive pills (ECPs)?"
2522:
1154:
1117:
1050:
608:
386:) pills used to be available as dedicated emergency contraceptive pills under several brand names:
326:
246:
240:
4310:
1549:
46:
6586:
6323:
6308:
6298:
6204:
6159:
6079:
5832:
5148:
FDA (February 5, 1975). "Diethylstilbestrol as postcoital oral contraceptive; patient labeling".
4897:
4781:
4646:
4545:
4448:
3948:"Summary of Product Characteristics: Levonelle One Step 1500 mcg; 5.1 Pharmacodynamic properties"
3435:
3359:
2919:
2387:
2270:
1839:
1600:
1334:
1176:
904:
792:
772:
744:
717:
496:
318:
221:
5237:
5231:
4134:"NorLevo 1.5 mg tablet Summary of Product Characteristics: 5.1 Pharmacodynamic properties (SPC)"
3235:
4677:
3256:
Turok DK, Gero A, Simmons RG, Kaiser JE, Stoddard GJ, Sexsmith CD, et al. (January 2021).
2750:"Mechanisms of action of mifepristone and levonorgestrel when used for emergency contraception"
6565:
6215:
6184:
5657:
5273:
5241:
5210:
5128:
5017:
4976:
4941:
4905:
4862:
4773:
4638:
4553:
4510:
4483:
4456:
4413:
4378:
4340:
4222:
in endometrial thickness from a baseline of 10.3 ± 2.3 mm to 9.7 ± 1.8 mm (vs. a 1.3 ± 2.3 mm
4209:
3848:
3790:
3760:
3725:
3690:
3641:
3614:
3573:
3443:
3396:
3347:
3337:
3287:
3203:
3173:
3093:
3055:
2982:
2911:
2871:
2817:
2771:
2730:
2681:
2615:
2582:
2533:
2422:
2379:
2327:
2297:
2262:
2219:
2184:
2103:
2072:
1986:
1831:
1722:
1698:
1649:
1592:
1526:
1494:
1484:
1390:
1382:
1372:
1326:
1291:
1237:
1054:
572:
553:
5684:"Beyond the Issue of Pharmacist Refusals: Pharmacies That Won't Sell Emergency Contraception"
3191:
RCOG Faculty of Sexual; Reproductive Healthcare; Clinical Effectiveness Unit (January 2012).
3117:
3014:. London: Royal College of Obstetricians and Gynaecologists. pp. 107–115. Archived from
2521:
RCOG Faculty of Sexual; Reproductive Healthcare; Clinical Effectiveness Unit (January 2012).
755:(IUDs) as emergency contraceptives is to prevent fertilization because of copper toxicity to
6328:
5007:
4968:
4933:
4889:
4854:
4825:
4765:
4630:
4537:
4440:
4405:
4370:
4199:
4191:
3752:
3717:
3680:
3672:
3604:
3563:
3427:
3388:
3277:
3269:
3163:
3155:
3085:
2907:
2903:
2861:
2853:
2807:
2761:
2720:
2712:
2673:
2414:
2371:
2254:
2211:
2176:
2143:
2062:
2054:
1976:
1823:
1688:
1680:
1639:
1631:
1620:"Medical regimens for abortion at 12 weeks and above: a systematic review and meta-analysis"
1584:
1318:
1281:
1273:
1227:
1219:
1125:
1005:
845:
In 2002, China became the first country in which mifepristone was registered for use as EC.
588:
531:
379:
282:
263:
31:
5410:
3118:"Fact sheet on the safety of levonorgestrel-alone emergency contraceptive pills (LNG ECPs)"
1023:
On July 28, 1999, the FDA approved the prescription progestin-only Plan B (two 750 μg
6265:
5731:
5718:
4753:
4002:
altering the endometrium). It is not effective once the process of implantation has begun.
3661:"Testing and Treatment After Adolescent Sexual Assault in Pediatric Emergency Departments"
908:
863:
799:
752:
552:
There are no medical conditions in which progestin-only ECPs are contraindicated. Current
314:
294:
267:
5438:"Barr Launches Plan B OTC/Rx Dual-Label Product; Awarded 3 Years New Product Exclusivity"
3659:
Schilling S, Samuels-Kalow M, Gerber JS, Scribano PV, French B, Wood JN (December 2015).
4287:. Silver Spring, Md.: FDA Center for Drug Evaluation and Research (CDER). pp. 4–5.
4017:(FIGO) and International Consortium for Emergency Contraception (ICEC) (April 4, 2011).
2716:
2677:
1693:
1668:
6596:
6439:
6434:
6426:
6382:
6084:
5910:
5463:
5388:
5353:
5121:
5012:
4995:
4204:
4179:
3992:
Duramed Pharmaceuticals/Barr Pharmaceuticals (now Teva Women's Health) (July 9, 2010).
3685:
3660:
3609:
3592:
3488:
3451:
3282:
3257:
3168:
3143:
2866:
2841:
2725:
2700:
2067:
2042:
1912:. New York: International Consortium for Emergency Contraception (ICEC). Archived from
1644:
1619:
1286:
1261:
1232:
1207:
1143:
1024:
791:
The first widely used methods were five-day treatments with high-dose estrogens, using
784:
632:
592:
524:
492:
310:
4937:
4769:
4732:
3756:
3721:
3392:
2418:
2375:
2258:
2215:
2180:
6630:
6094:
6039:
5842:
5812:
5752:
Educational web site with information for women who need emergency contraception now.
4634:
4409:
4195:
4178:
Stratton P, Levens ED, Hartog B, Piquion J, Wei Q, Merino M, Nieman LK (April 2010).
3999:. Silver Spring, Md.: FDA Center for Drug Evaluation and Research (CDER). p. 4.
1604:
1483:. Cleland, K; Schwarz, EB (21st ed.). New York: Ardent Media. pp. 329–356.
1112:
867:
831:
557:
410:
346:
258:
217:
5486:"Plan B will be available to 15-year-olds, but they might need a passport to get it"
4785:
4650:
3963:"Summary of Product Characteristics: NorLevo 1.5 mg; 5.1 Pharmacodynamic properties"
3632:
Diamond EF (March 1978). "Physician notes hazards of DES use to prevent pregnancy".
2923:
2391:
2274:
1843:
1723:"Certain combined oral contraceptives for use as postcoital emergency contraception"
1338:
6611:
6606:
6581:
6555:
6534:
6526:
6521:
6479:
6469:
6402:
6397:
6338:
6089:
6044:
6012:
5872:
4698:
4241:"Summary of Product Characteristics: ellaOne 30 mg; 5.1 Pharmacodynamic properties"
3789:(5th ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 153–166.
2058:
1874:
1066:
1062:
960:
756:
740:
616:
520:
475:
The most common side effect reported by users of emergency contraceptive pills was
372:
322:
3529:
1784:
285:, which is a drug regimen administered to terminate pregnancies in any trimester.
17:
3159:
2812:
2795:
1827:
1223:
6511:
6464:
6377:
6367:
6348:
6117:
6104:
5773:
5321:
4374:
3009:"UK medical eligibility criteria for contraceptive use: Emergency contraception"
1106:
811:
704:
512:
275:
5774:
Use of Emergency Contraception Among Women Aged 15–44, United States, 2006–2010
4959:
Kuchera LK (October 1971). "Postcoital contraception with diethylstilbestrol".
4571:
4021:. London: International Federation of Gynecology and Obstetrics. Archived from
3591:
Glover D, Gerety M, Bromberg S, Fullam S, DiVasto P, Kaufman A (October 1976).
3308:
1814:
Gemzell-Danielsson K, Rabe T, Cheng L (March 2013). "Emergency contraception".
1635:
1588:
1208:"Emergency contraception review: evidence-based recommendations for clinicians"
874:. In their February 2014 emergency review article, Trussell and Raymond note:
6601:
6444:
6280:
6074:
5877:
4277:
4236:
4129:
4104:
3958:
3351:
2701:"Menstrual bleeding patterns following levonorgestrel emergency contraception"
2320:"Levonorgestrel is more effective, has fewer side-effects, than Yuzpe regimen"
2012:
2004:
1684:
1498:
1070:
819:
596:
485:
383:
361:
4858:
4756:(August 1998). "Time for emergency contraception with levonorgestrel alone".
3980:
implantation. It is not effective once the process of implantation has begun.
3207:
3089:
3040:
2537:
1394:
1386:
6498:
6474:
6333:
6303:
5916:
5887:
5768:
3258:"Levonorgestrel vs. Copper Intrauterine Devices for Emergency Contraception"
2766:
2749:
2111:
1277:
1045:
On April 30, 2013, the FDA approved (with three-year marketing exclusivity)
699:) levonorgestrel emergency contraceptive pills (based on labels for regular
612:
508:
504:
470:
466:
338:
236:
225:
66:
5021:
4972:
4945:
4557:
4514:
4417:
4344:
4213:
3764:
3694:
3676:
3577:
3568:
3551:
3291:
3177:
3097:
3076:
Davidoff F, Trussell J (October 2006). "Plan B and the politics of doubt".
3059:
2915:
2875:
2857:
2821:
2775:
2734:
2685:
2426:
2383:
2331:
2301:
2223:
2188:
2107:
2076:
1990:
1835:
1702:
1653:
1596:
1330:
1295:
1241:
1073:—without a prescription to anyone age 17 or over who can show proof of age.
4980:
4909:
4866:
4800:"Japan considers making morning-after pill available without prescription"
4777:
4487:
4460:
4382:
3729:
3618:
3447:
3400:
3273:
3144:"Ectopic pregnancy and emergency contraceptive pills: a systematic review"
2266:
1322:
959:
Only one pharmaceutical company, Tablicaps, Inc., a small manufacturer of
903:
editorial calling attention to previously published studies on the use of
349:") have also been shown to be effective as emergency contraceptive pills.
6290:
6254:
5837:
3645:
3015:
2935:
2933:
1147:
1058:
500:
480:
479:
14 to 23% of levonorgestrel-only users and 50.5% of Yuzpe regimen users;
271:
5781:
5764:
by the Adolescent Medicine Committee, Canadian Pediatric Society (CPS),
2840:
American Academy of Pediatrics Committee on Adolescence (October 2005).
2606:
WHO Department of Reproductive Health and Research (December 31, 2004).
2573:
WHO Department of Reproductive Health and Research (December 31, 2004).
1778:"Emergency contraception: a last chance to prevent unintended pregnancy"
5505:. Silver Spring, Md.: U.S. Food and Drug Administration. April 30, 2013
5270:
Late lessons from early warnings: the precautionary principle 1896–2000
4901:
4642:
4549:
4452:
3815:
The use of progesterone receptor modulators for emergency contraception
3439:
803:
365:
330:
82:
2947:. Beltsville, Md.: Food and Drug Administration. pp. 32–7, 133–77
2036:
2034:
1981:
1964:
6034:
4155:. London: European Medicines Agency. January 24, 2014. Archived from
4136:. Dublin: Irish Pharmaceutical Healthcare Association. Archived from
3965:. Dublin: Irish Pharmaceutical Healthcare Association. Archived from
646:
476:
298:
4893:
4541:
4444:
3994:"Prescribing information: Plan B One-Step; 12.1 Mechanism of action"
3431:
2016:
795:(DES) in the US and ethinylestradiol in the Netherlands by Haspels.
5712:
Emergency Contraceptive Pills Medical and Service Delivery Guidance
4695:"Emergency Contraception: Using emergency contraceptives worldwide"
3416:"History and efficacy of emergency contraception: beyond Coca-Cola"
1371:(20th revised ed.). New York: Ardent Media. pp. 113–145.
5209:(10th ed.). New York: Irvington Publishers. pp. 128–33.
3193:"Clinical guidance: drug interactions with hormonal contraception"
1944:. New York: European Consortium for Emergency Contraception (ECEC)
1618:
Whitehouse K, Brant A, Fonhus MS, Lavelanet A, Ganatra B (2020).
571:
ECPs, like all other contraceptives, reduce the absolute risk of
3847:(6th ed.). Philadelphia: Mosby Elsevier. pp. 215–272.
2894:
Grimes DA, Raymond EG (August 2002). "Emergency contraception".
2794:
American College of Obstetricians and Gynecologists (May 2010).
2699:
Gainer E, Kenfack B, Mboudou E, Doh AS, Bouyer J (August 2006).
1260:
Cleland K, Zhu H, Goldstuck N, Cheng L, Trussell J (July 2012).
925:
760:
167:
IUDs may be subsequently left in place for ongoing contraception
6219:
5785:
5268:. In in Harremoës, Poul; Gee, David; Vaz, Sofia Guedes (eds.).
3041:"U S. Medical Eligibility Criteria for Contraceptive Use, 2010"
2981:(4th ed.). Geneva: World Health Organization. p. 63.
2940:
FDA Center for Drug Evaluation and Research (August 22, 2006).
414:
the more effective and better-tolerated options are available.
135:
Consider need for STI screening and ongoing birth control needs
4246:. London: European Medicines Agency. p. 7. Archived from
3872:
application for approval in the United States is under review.
3334:
Contraceptive technology—Chapter 5—Intrauterine Devices (IUDs)
3142:
Cleland K, Raymond E, Trussell J, Cheng L, Zhu H (June 2010).
1206:
Cleland K, Raymond EG, Westley E, Trussell J (December 2014).
1124:
caused a historical survey to be conducted and concluded that
368:
in the United States), Duprisal 30, Ulipristal 30, and UPRIS.
5746:. Information for women who need emergency contraception now.
5347:"Pharmacists protocol for dispensing emergency contraception"
5272:. Copenhagen: European Environmental Agency. pp. 84–92.
3202:. London: Royal College of Obstetricians and Gynaecologists.
2532:. London: Royal College of Obstetricians and Gynaecologists.
607:
An effective emergency contraception measure is the copper-T
4595:. UK Family Planning Association. April 2006. Archived from
3950:. London: electronic Medicines Compendium (eMC), Datapharm.
1120:
services without financial, professional, or legal penalty.
2970:
WHO Department of Reproductive Health and Research (2009).
2441:"Morning-after pill doesn't work for women over 176 pounds"
729:
saying it cannot prevent implantation of a fertilized egg.
453:
who weigh over 80 kg (176 lb). After a review by
5755:
5724:
5236:(11th ed.). New York: Irvington Publishers. pp.
4041:• May possibly prevent the sperm and the egg from meeting.
2041:
Shen J, Che Y, Showell E, Chen K, Cheng L (January 2019).
1809:
1807:
1805:
4356:
4354:
4282:"Prescribing information: Ella; 12.1 Mechanism of action"
4109:"NorLevo 1.5 mg tablet Patient Information Leaflet (PIL)"
3303:
3301:
2796:"ACOG Practice Bulletin No. 112: Emergency contraception"
1479:
Trussell J (2019). "Chapter 10 Emergency Contraception".
739:
emergency contraceptive pills like low-dose and mid-dose
270:, from day 21 after giving birth, or from day five after
3007:
RCOG Faculty of Sexual; Reproductive Healthcare (2009).
1721:
Food and Drug Administration (FDA) (February 25, 1997).
5263:"The DES story: long-term consequences of prenatal use"
4431:
Johnson JH (1984). "Contraception--the morning after".
2612:
Selected practice recommendations for contraceptive use
2579:
Selected practice recommendations for contraceptive use
1910:"EC pill types and countries of availability, by brand"
917:
on the use of DES as a postcoital contraceptive at the
798:
In the early 1970s, the Yuzpe regimen was developed by
127:
Pregnancy test required if no period seen after 3 weeks
5479:
5477:
725:(EMA) approved a change to the label for HRA Pharma's
5651:"Stormans, Inc. v. John Wiesman – Dissenting Opinion"
5525:"U.S. Drops Bid to Limit Sales of Morning-After Pill"
4826:"Calls rise for prescription-free morning-after pill"
4015:
International Federation of Gynecology and Obstetrics
3593:"Diethylstilbestrol in the treatment of rape victims"
1866:
Trussell, James; Cleland, Kelly (February 13, 2013).
1003:
On February 25, 1997, the FDA posted a notice in the
713:
International Federation of Gynecology and Obstetrics
194:
Ulipristal acetate or mifepristone pill within 5 days
27:
Birth control measures taken after sexual intercourse
5756:
International Consortium for Emergency Contraception
5725:
The Emergency Contraception Website (not-2-late.com)
5123:
Worse than the disease: pitfalls of medical progress
4996:"Selected items from the FDA drug bulletin-may 1973"
2748:
Gemzell-Danielsson K, Marions L (July–August 2004).
6574:
6543:
6488:
6453:
6411:
6356:
6347:
6289:
6253:
6197:
6168:
6133:
6126:
6103:
6063:
6025:
6003:
5975:
5935:
5926:
5901:
5856:
5820:
5758:
Policy-oriented web site directed at professionals.
5035:
5033:
5031:
4617:Breese, G. R.; Smith, R. D.; Cooper, B. R. (1975).
2614:(2nd ed.). Geneva: World Health Organization.
2581:(2nd ed.). Geneva: World Health Organization.
1868:"Dedicated emergency contraceptive pills worldwide"
1776:Trussell J, Raymond EG, Cleland K (February 2014).
527:. (Earlier testing may not give accurate results.)
179:
171:
163:
155:
144:
139:
131:
123:
118:
106:
96:
91:
81:
73:
61:
56:
39:
5345:California Board of Pharmacy (December 22, 2004).
5120:
4396:"FDA considers DES safe as 'morning-after' pill".
4037:Levonorgestrel-only emergency contraceptive pills:
2979:Medical eligibility criteria for contraceptive use
2288:"Counsel women to take ECPs as soon as possible".
1138:Almost all 50 states have implemented policies on
5186:FDA (March–April 1978). "DES and Breast Cancer".
3039:CDC Division of Reproductive Health (June 2010).
2459:"FYI: Why Doesn't Plan B Work For Heavier Women?"
1771:
1769:
1767:
1765:
1763:
5744:Association of Reproductive Health Professionals
5073:
5071:
4361:Demers LM (May 1971). "The morning-after pill".
3910:
3908:
3906:
3904:
3526:Association of Reproductive Health Professionals
3485:Association of Reproductive Health Professionals
3071:
3069:
2479:. European Medicines Agency. 17 September 2018.
1942:"Emergency contraception availability in Europe"
1861:
1859:
1857:
1855:
1853:
1761:
1759:
1757:
1755:
1753:
1751:
1749:
1747:
1745:
1743:
4035:
3929:"Drug's nickname may have aided politicization"
3860:
3802:
3780:
3778:
3776:
3774:
3125:
2965:
2963:
2961:
2659:
2657:
2549:
2516:
2514:
2512:
2510:
2508:
2506:
2504:
2502:
2500:
2498:
1400:
1362:
1360:
1358:
1356:
1354:
1352:
1350:
1348:
1088:Emergency contraceptive availability by country
876:
427:
235:, are medications intended to disrupt or delay
5464:"F.D.A. Easing Access to 'Morning After' Pill"
3917:"No abortion role seen for morning-after pill"
3884:
3882:
3880:
3002:
3000:
2998:
2889:
2887:
2885:
941:approved postcoital contraceptive use of DES).
6231:
5797:
3710:American Journal of Obstetrics and Gynecology
1425:Progestin-only emergency contraceptive pills.
8:
5261:Ibarreta, Dolores; Swain, Shanna H. (2001).
4153:"Review of emergency contraceptives started"
3336:(21st ed.). New York, NY. p. 159.
2789:
2787:
2785:
2523:"Clinical guidance: emergency contraception"
1935:
1933:
1931:
1903:
1901:
1899:
1897:
1895:
1577:Journal of Obstetrics and Gynaecology Canada
6247:Active molecules in hormonal contraceptives
3510:"Effectiveness of Emergency Contraceptives"
3111:
3109:
3107:
2835:
2833:
2831:
2356:
2354:
2352:
2239:
2237:
2235:
2233:
2047:The Cochrane Database of Systematic Reviews
2043:"Interventions for emergency contraception"
1673:The Cochrane Database of Systematic Reviews
1544:
1542:
6353:
6238:
6224:
6216:
6130:
5932:
5838:Preventing sexually-transmitted infections
5804:
5790:
5782:
5114:
5112:
4039:• Interfere with the process of ovulation;
3550:Committee on Adolescence (December 2012).
3364:: CS1 maint: location missing publisher (
1716:
1714:
1712:
695:-approved labels (except for HRA Pharma's
281:Emergency contraception is not related to
45:
5436:Barr Pharmaceuticals (November 6, 2006).
5127:. Cambridge: Cambridge University Press.
5011:
4593:"Contraception: past, present and future"
4503:Aggiornamenti in Ostetricia e Ginecologia
4203:
3838:
3836:
3834:
3684:
3608:
3567:
3281:
3167:
2942:"Plan B Rx to OTC switch Medical Reviews"
2865:
2811:
2765:
2724:
2066:
1980:
1692:
1643:
1285:
1255:
1253:
1251:
1231:
1201:
1199:
1197:
838:in the UK discontinued October 2001, and
4623:Pharmacology, Biochemistry, and Behavior
5594:
5592:
5590:
5588:
5573:
5571:
4303:"Birth Control: The Morning-After Pill"
3745:American Journal of Preventive Medicine
2908:10.7326/0003-4819-137-3-200208060-00010
2324:Progress in Human Reproduction Research
1516:
1514:
1512:
1510:
1508:
1432:Combined emergency contraceptive pills.
1193:
1094:COVID-19 pandemic in the United Kingdom
5645:
5643:
5641:
5621:"Insurance Coverage of Contraceptives"
5615:
5613:
5611:
5609:
3357:
2972:"Emergency contraceptive pills (ECPs)"
2009:"Countries where ellaOne was launched"
1182:Reproductive Health Supplies Coalition
1153:Under federal law, a provision of the
515:a few days after the pills are taken.
36:
5777:National Center for Health Statistics
5579:"Refusing to Provide Health Services"
4065:"How morning-after pills really work"
753:copper-releasing intrauterine devices
243:, which are necessary for pregnancy.
7:
5843:Over-the-counter oral contraceptives
5523:Shear MD, Belluck P (10 June 2013).
5045:. Washington: U.S. Govt. Print. Off.
4530:International Family Planning Digest
4476:The Journal of Reproductive Medicine
3309:"Copper IUD as EC | Beyond the Pill"
3123:. Geneva: World Health Organization.
1474:
1472:
1470:
1468:
1466:
5828:Comparison of birth control methods
4363:The New England Journal of Medicine
3514:The Emergency Contraception Website
3479:. Office of Population Research at
3477:The Emergency Contraception Website
3262:The New England Journal of Medicine
2717:10.1016/j.contraception.2006.02.009
2678:10.1016/j.contraception.2005.10.006
2483:from the original on 4 October 2018
751:The primary mechanism of action of
735:The primary mechanism of action of
382:) and progestin (levonorgestrel or
6205:Male contraceptives in development
5233:Contraceptive Technology 1982–1983
5207:Contraceptive Technology 1980–1981
4276:Watson Pharma (under license from
3804:Emergency postcoital contraception
3787:A clinical guide for contraception
3473:"What is Emergency Contraception?"
3426:(2). Guttmacher Institute: 44–48.
1212:Clinical Obstetrics and Gynecology
111:
87:Emergency postcoital contraception
25:
3895:Talk of the Nation Science Friday
3048:MMWR. Recommendations and Reports
2142:. August 24, 2006. Archived from
911:, and a large study published in
907:as a postcoital contraceptive at
343:combined oral contraceptive pills
197:Levonorgestrel pill within 3 days
4410:10.1001/jama.1973.03220260003002
4196:10.1016/j.fertnstert.2008.12.057
3414:Ellertson C (March–April 1996).
5848:Oral contraceptive formulations
4114:. Dublin: Irish Medicines Board
4085:Belluck P (November 26, 2013).
3597:The Western Journal of Medicine
3528:. November 2006. Archived from
3487:. November 2006. Archived from
3130:the sperm and egg from meeting.
3127:Can LNG ECPs cause an abortion?
2290:Contraceptive Technology Update
1162:different levels; for example,
1027:pills) emergency contraceptive.
900:New England Journal of Medicine
737:progesterone receptor modulator
640:sexually transmitted infections
513:progestogen withdrawal bleeding
51:An emergency contraception pill
6383:Norethisterone (norethindrone)
2059:10.1002/14651858.CD001324.pub6
1047:Teva Pharmaceutical Industries
691:-approved labels and European
663:American Academy of Pediatrics
547:American Academy of Pediatrics
295:unprotected sexual intercourse
191:Copper IUD within 5 to 10 days
1:
5736:Office of Population Research
5462:Gardiner H (April 22, 2009).
4938:10.1016/S0010-7824(99)00090-6
4770:10.1016/S0140-6736(98)22032-0
4043:Implications of the research:
3927:Belluck, Pam (June 6, 2012).
3915:Belluck, Pam (June 6, 2012).
3757:10.1016/S0749-3797(00)00243-9
3722:10.1016/S0002-9378(96)70141-2
3518:Office of Population Research
3393:10.1016/S0010-7824(86)80011-7
2419:10.1016/S0010-7824(03)00110-0
2376:10.1016/S0140-6736(02)11767-3
2259:10.1016/S0140-6736(98)05145-9
2216:10.1016/S0010-7824(02)00535-8
2181:10.1016/S0010-7824(99)00018-9
2090:Weismiller DG (August 2004).
1409:Emergency contraceptive pills
471:Progestin § Mood changes
467:Progestin § Side effects
289:Emergency contraceptive pills
257:Emergency contraception is a
5766:Paediatrics and Child Health
5750:Planned Parenthood web site.
5656:. 2016-06-28. Archived from
5416:Food and Drug Administration
5384:Food and Drug Administration
5317:Food and Drug Administration
4882:Family Planning Perspectives
4673:Food and Drug Administration
4635:10.1016/0091-3057(75)90023-4
4536:(3): 11–12. September 1975.
4433:Family Planning Perspectives
4404:(12): 1581–1582. June 1973.
4331:"Postcoital contraception".
4309:. 1966-05-06. Archived from
3420:Family Planning Perspectives
3160:10.1097/AOG.0b013e3181dd22ef
2813:10.1097/AOG.0b013e3181deff2a
2140:Food and Drug Administration
1828:10.3109/09513590.2013.774591
1521:"7. Genito-urinary System".
1224:10.1097/GRF.0000000000000056
566:acute intermittent porphyria
530:Existing pregnancy is not a
407:Food and Drug Administration
341:, or both) found in regular
140:Advantages and disadvantages
6561:Medroxyprogesterone acetate
6532:Spironolactone derivatives:
6155:Fertility awareness methods
4375:10.1056/NEJM197105062841813
3332:Dean G, Schwarz EB (2019).
2896:Annals of Internal Medicine
1816:Gynecological Endocrinology
6658:
6642:Intrauterine contraception
4063:editorial (June 9, 2012).
3889:Flatow I (June 15, 2012).
3603:(4). West J Med: 331–334.
2477:"Emergency contraceptives"
2133:"Plan B label information"
1963:Italia S, Brand H (2016).
1636:10.1016/j.conx.2020.100037
1589:10.1016/j.jogc.2021.12.010
1085:
653:High-risk sex and abortion
583:The herbal preparation of
562:inflammatory bowel disease
464:
69:or others) or intrauterine
29:
6150:Calendar (rhythm) methods
5734: – by the
5600:"Emergency Contraception"
5411:"Plan B information page"
5379:"Plan B approval package"
5309:"Preven approval package"
5307:FDA (September 1, 1998).
5119:Dutton, Diana B. (1988).
4824:NHK (December 26, 2020).
3552:"Emergency contraception"
3148:Obstetrics and Gynecology
2842:"Emergency contraception"
2800:Obstetrics and Gynecology
2754:Human Reproduction Update
2096:American Family Physician
2092:"Emergency contraception"
1685:10.1002/14651858.ED000142
1550:"Emergency contraception"
1447:"Emergency Contraception"
1418:Ulipristal acetate (UPA).
853:Calculating effectiveness
824:World Health Organization
723:European Medicines Agency
543:World Health Organization
455:European Medicines Agency
443:World Health Organization
184:
44:
6422:Norethisterone enanthate
6393:Norethisterone enanthate
6276:Testosterone undecanoate
4859:10.1001/jama.244.12.1336
3946:Bayer (March 22, 2010).
3845:Comprehensive gynecology
3090:10.1001/jama.296.14.1775
1481:Contraceptive technology
1369:Contraceptive technology
701:oral contraceptive pills
627:As regular contraception
556:, current or history of
188:Use as soon as possible.
30:Not to be confused with
6065:Emergency Contraception
5762:Emergency contraception
5484:Kliff S (May 1, 2013).
5409:FDA (August 24, 2006).
4184:Fertility and Sterility
3862:Emergency contraception
2296:(7): 75–77. July 1999.
1164:Stormans, Inc v Wiesman
1131:Griswold v. Connecticut
834:discontinued May 2004,
781:Yale School of Medicine
210:Emergency contraception
92:Failure rates (per use)
40:Emergency contraception
6637:Hormonal contraception
6592:Algestone acetophenide
6388:Norethisterone acetate
6271:Testosterone buciclate
5985:Multi-month injections
5928:Hormonal contraception
5892:Levonorgestrel implant
5858:Long-acting reversible
5554:Pharmaceutical Journal
4973:10.1001/jama.218.4.562
4053:
3874:
3828:
3808:Mechanism and efficacy
3677:10.1542/peds.2015-2093
3569:10.1542/peds.2012-2962
3313:beyondthepill.ucsf.edu
3132:
2858:10.1542/peds.2005-1877
2563:
1969:Public Health Genomics
1822:(Supplement 1): 1–14.
1436:
919:University of Michigan
881:
771:In 1966, gynecologist
554:venous thromboembolism
431:
366:Watson Pharmaceuticals
6551:Chlormadinone acetate
6113:Vaginal pH modulation
6090:Low-dose mifepristone
5990:Progestogen-only pill
5884:Contraceptive implant
5377:FDA (July 28, 1999).
4333:IPPF Medical Bulletin
3274:10.1056/NEJMoa2022141
2767:10.1093/humupd/dmh027
1790:on September 23, 2010
1404:Copper-releasing IUCs
1323:10.1592/phco.30.2.158
1278:10.1093/humrep/des140
1034:On November 6, 2006,
947:new drug applications
937:was that the FDA had
703:) say they may cause
669:EC and sexual assault
297:or the breakage of a
112:Effectiveness of ECPs
100:ECP: see article text
6145:Breastfeeding method
6055:Contraceptive sponge
5939:estrogen–progestogen
5888:Etonogestrel implant
5740:Princeton University
5688:Guttmacher Institute
5625:Guttmacher Institute
5359:on December 11, 2006
5040:U.S. Senate (1975).
4501:Valle G (1975). "".
3522:Princeton University
3481:Princeton University
2640:"Morning-after pill"
1036:Barr Pharmaceuticals
872:long been recognized
777:Gertrude Van Wagenen
409:(FDA) approved this
247:Intrauterine devices
220:measure, used after
6517:Nomegestrol acetate
6507:Segesterone acetate
6373:Etynodiol diacetate
6319:Estradiol enanthate
6314:Estradiol cypionate
6180:Non-penetrative sex
6172:vaginal intercourse
6137:vaginal intercourse
5957:Contraceptive patch
5952:Extended cycle Pill
5869:Intrauterine device
5833:Male contraceptives
5000:California Medicine
4994:FDA (August 1973).
2465:. 27 November 2013.
2370:(9348): 1803–1810.
1402:Mechanism of action
1155:Affordable Care Act
1118:reproductive health
711:In March 2011, the
678:Mechanism of action
609:intrauterine device
603:Intrauterine device
378:Combined estrogen (
353:ECPs are available
110:% (please see
6587:Ulipristal acetate
6454:Third generation (
6357:First generation (
6324:Estradiol valerate
6309:Estradiol benzoate
6299:Diethylstilbestrol
6080:Ulipristal acetate
6068:(Post-intercourse)
5962:Monthly injections
5730:2021-04-26 at the
5717:2022-05-05 at the
5529:The New York Times
5468:The New York Times
4239:(March 15, 2012).
4091:The New York Times
4069:The New York Times
3933:The New York Times
3921:The New York Times
3671:(6): e1495–e1503.
1556:. 30 December 2016
1266:Human Reproduction
1177:Rape crisis center
793:diethylstilbestrol
773:John McLean Morris
745:ulipristal acetate
371:The antiprogestin
319:ulipristal acetate
313:, LNG) pills; and
233:morning-after pill
222:sexual intercourse
18:Morning-after pill
6624:
6623:
6620:
6619:
6566:Megestrol acetate
6489:Fourth generation
6412:Second generation
6213:
6212:
6193:
6192:
6021:
6020:
5279:978-92-9167-323-0
5247:978-0-8290-0705-3
5216:978-0-8290-0084-9
5134:978-0-521-34023-6
4853:(12): 1336–1339.
4764:(9126): 416–417.
4735:. Fertility. 2002
4369:(18): 1034–1036.
4280:) (May 2, 2012).
4159:on March 27, 2014
4132:(November 2013).
4107:(November 2013).
3961:(July 19, 2011).
3854:978-0-323-06986-1
3796:978-1-60831-610-6
3634:Hospital Progress
3200:Clinical Guidance
3084:(14): 1775–1778.
2988:978-92-4-156388-8
2621:978-92-4-156284-3
2588:978-92-4-156284-3
2551:How does EC work?
2530:Clinical Guidance
2253:(9126): 428–433.
1982:10.1159/000444686
1532:978-0-85711-369-6
1378:978-1-59708-004-0
1055:birth certificate
982:FDA Drug Bulletin
980:In March 1978, a
935:FDA Drug Bulletin
930:FDA Drug Bulletin
573:ectopic pregnancy
509:breast tenderness
207:
206:
16:(Redirected from
6649:
6354:
6329:Ethinylestradiol
6240:
6233:
6226:
6217:
6131:
5977:Progestogen-only
5933:
5806:
5799:
5792:
5783:
5699:
5698:
5696:
5695:
5680:
5674:
5671:
5665:
5664:
5662:
5655:
5647:
5636:
5635:
5633:
5632:
5617:
5604:
5603:
5602:. 14 March 2016.
5596:
5583:
5582:
5581:. 14 March 2016.
5575:
5566:
5565:
5563:
5561:
5546:
5540:
5539:
5537:
5535:
5520:
5514:
5513:
5511:
5510:
5499:
5497:
5496:
5481:
5472:
5471:
5459:
5453:
5452:
5450:
5449:
5440:. Archived from
5433:
5427:
5426:
5424:
5423:
5406:
5400:
5399:
5397:
5396:
5387:. Archived from
5374:
5368:
5367:
5365:
5364:
5358:
5352:. Archived from
5351:
5342:
5336:
5335:
5333:
5332:
5326:
5320:. Archived from
5313:
5304:
5298:
5297:
5295:
5294:
5288:
5282:. Archived from
5267:
5258:
5252:
5251:
5227:
5221:
5220:
5202:
5196:
5195:
5183:
5177:
5176:
5164:
5158:
5157:
5145:
5139:
5138:
5126:
5116:
5107:
5106:
5094:
5088:
5087:
5075:
5066:
5065:
5064:(186): 26809–11.
5053:
5047:
5046:
5037:
5026:
5025:
5015:
4991:
4985:
4984:
4956:
4950:
4949:
4920:
4914:
4913:
4888:(2): 58–64, 87.
4877:
4871:
4870:
4842:
4836:
4835:
4833:
4832:
4821:
4815:
4814:
4812:
4811:
4796:
4790:
4789:
4750:
4744:
4743:
4741:
4740:
4729:
4723:
4721:
4709:
4703:
4702:
4697:. Archived from
4691:
4685:
4684:
4682:
4676:. Archived from
4669:
4661:
4655:
4654:
4629:(6): 1097–1106.
4614:
4608:
4607:
4605:
4604:
4589:
4583:
4582:
4580:
4579:
4574:. Medscape. 2002
4568:
4562:
4561:
4525:
4519:
4518:
4498:
4492:
4491:
4471:
4465:
4464:
4428:
4422:
4421:
4393:
4387:
4386:
4358:
4349:
4348:
4328:
4322:
4321:
4319:
4318:
4313:on April 8, 2008
4299:
4293:
4292:
4286:
4273:
4267:
4266:
4260:
4258:
4252:
4245:
4233:
4227:
4217:
4207:
4190:(6): 2035–2041.
4175:
4169:
4168:
4166:
4164:
4149:
4147:
4145:
4140:on March 5, 2014
4126:
4121:
4119:
4113:
4101:
4099:
4097:
4082:
4076:
4075:
4060:
4054:
4034:
4032:
4030:
4025:on July 20, 2022
4011:
4005:
4004:
3998:
3989:
3983:
3982:
3976:
3974:
3969:on June 15, 2012
3955:
3943:
3937:
3936:
3924:
3912:
3899:
3898:
3897:. New York: NPR.
3886:
3875:
3858:
3840:
3829:
3800:
3782:
3769:
3768:
3740:
3734:
3733:
3705:
3699:
3698:
3688:
3656:
3650:
3649:
3629:
3623:
3622:
3612:
3588:
3582:
3581:
3571:
3562:(6): 1174–1182.
3547:
3541:
3540:
3538:
3537:
3506:
3500:
3499:
3497:
3496:
3469:
3463:
3462:
3460:
3459:
3450:. Archived from
3411:
3405:
3404:
3376:
3370:
3369:
3363:
3355:
3329:
3323:
3322:
3320:
3319:
3305:
3296:
3295:
3285:
3253:
3247:
3246:
3244:
3243:
3232:
3226:
3225:
3223:
3222:
3216:
3210:. Archived from
3197:
3188:
3182:
3181:
3171:
3154:(6): 1263–1266.
3139:
3133:
3124:
3122:
3113:
3102:
3101:
3073:
3064:
3063:
3045:
3036:
3030:
3029:
3027:
3026:
3020:
3013:
3004:
2993:
2992:
2976:
2967:
2956:
2955:
2953:
2952:
2946:
2937:
2928:
2927:
2891:
2880:
2879:
2869:
2852:(4): 1026–1035.
2837:
2826:
2825:
2815:
2806:(5): 1100–1109.
2791:
2780:
2779:
2769:
2745:
2739:
2738:
2728:
2696:
2690:
2689:
2661:
2652:
2651:
2649:
2647:
2636:
2630:
2629:
2624:. Archived from
2603:
2597:
2596:
2591:. Archived from
2570:
2564:
2547:
2545:
2544:
2527:
2518:
2493:
2492:
2490:
2488:
2473:
2467:
2466:
2455:
2449:
2448:
2437:
2431:
2430:
2402:
2396:
2395:
2358:
2347:
2346:
2344:
2343:
2334:. Archived from
2312:
2306:
2305:
2285:
2279:
2278:
2241:
2228:
2227:
2199:
2193:
2192:
2164:
2158:
2157:
2155:
2154:
2148:
2137:
2129:
2123:
2122:
2120:
2119:
2110:. Archived from
2087:
2081:
2080:
2070:
2038:
2029:
2028:
2026:
2024:
2019:on July 28, 2013
2015:. Archived from
2001:
1995:
1994:
1984:
1960:
1954:
1953:
1951:
1949:
1937:
1926:
1925:
1923:
1921:
1916:on April 5, 2016
1905:
1890:
1889:
1887:
1885:
1880:on March 4, 2016
1879:
1872:
1863:
1848:
1847:
1811:
1800:
1799:
1797:
1795:
1789:
1782:
1773:
1738:
1737:
1736:(37): 8610–8612.
1730:Federal Register
1727:
1718:
1707:
1706:
1696:
1679:(10): ED000142.
1664:
1658:
1657:
1647:
1615:
1609:
1608:
1572:
1566:
1565:
1563:
1561:
1554:womenshealth.gov
1546:
1537:
1536:
1518:
1503:
1502:
1476:
1461:
1460:
1458:
1457:
1443:
1437:
1398:
1364:
1343:
1342:
1306:
1300:
1299:
1289:
1272:(7): 1994–2000.
1257:
1246:
1245:
1235:
1203:
1126:right to privacy
1061:to a drug store
1051:driver's license
1006:Federal Register
532:contraindication
380:ethinylestradiol
355:over-the-counter
283:medical abortion
264:medical abortion
49:
37:
32:medical abortion
21:
6657:
6656:
6652:
6651:
6650:
6648:
6647:
6646:
6627:
6626:
6625:
6616:
6570:
6539:
6484:
6449:
6407:
6343:
6285:
6266:Dimethandrolone
6249:
6244:
6214:
6209:
6189:
6170:
6164:
6135:
6122:
6099:
6067:
6059:
6040:Internal condom
6035:External condom
6027:Barrier Methods
6017:
5999:
5971:
5938:
5922:
5897:
5859:
5852:
5816:
5810:
5732:Wayback Machine
5719:Wayback Machine
5708:
5703:
5702:
5693:
5691:
5682:
5681:
5677:
5672:
5668:
5660:
5653:
5649:
5648:
5639:
5630:
5628:
5619:
5618:
5607:
5598:
5597:
5586:
5577:
5576:
5569:
5559:
5557:
5548:
5547:
5543:
5533:
5531:
5522:
5521:
5517:
5508:
5506:
5501:
5500:
5494:
5492:
5483:
5482:
5475:
5461:
5460:
5456:
5447:
5445:
5435:
5434:
5430:
5421:
5419:
5408:
5407:
5403:
5394:
5392:
5376:
5375:
5371:
5362:
5360:
5356:
5349:
5344:
5343:
5339:
5330:
5328:
5324:
5311:
5306:
5305:
5301:
5292:
5290:
5286:
5280:
5265:
5260:
5259:
5255:
5248:
5229:
5228:
5224:
5217:
5204:
5203:
5199:
5185:
5184:
5180:
5166:
5165:
5161:
5147:
5146:
5142:
5135:
5118:
5117:
5110:
5105:(186): 26824–6.
5096:
5095:
5091:
5077:
5076:
5069:
5055:
5054:
5050:
5039:
5038:
5029:
4993:
4992:
4988:
4958:
4957:
4953:
4922:
4921:
4917:
4894:10.2307/2136125
4879:
4878:
4874:
4844:
4843:
4839:
4830:
4828:
4823:
4822:
4818:
4809:
4807:
4804:The Japan Times
4798:
4797:
4793:
4752:
4751:
4747:
4738:
4736:
4731:
4730:
4726:
4711:
4710:
4706:
4693:
4692:
4688:
4680:
4667:
4663:
4662:
4658:
4616:
4615:
4611:
4602:
4600:
4591:
4590:
4586:
4577:
4575:
4570:
4569:
4565:
4542:10.2307/2948217
4527:
4526:
4522:
4500:
4499:
4495:
4473:
4472:
4468:
4445:10.2307/2134916
4430:
4429:
4425:
4395:
4394:
4390:
4360:
4359:
4352:
4330:
4329:
4325:
4316:
4314:
4301:
4300:
4296:
4284:
4275:
4274:
4270:
4256:
4254:
4250:
4243:
4235:
4234:
4230:
4177:
4176:
4172:
4162:
4160:
4151:
4150:
4143:
4141:
4128:
4127:
4117:
4115:
4111:
4103:
4102:
4095:
4093:
4084:
4083:
4079:
4071:. p. A20.
4062:
4061:
4057:
4050:
4048:
4046:
4044:
4042:
4040:
4038:
4028:
4026:
4013:
4012:
4008:
3996:
3991:
3990:
3986:
3972:
3970:
3957:
3956:
3945:
3944:
3940:
3926:
3925:
3914:
3913:
3902:
3888:
3887:
3878:
3870:
3868:
3866:
3863:
3855:
3842:
3841:
3832:
3824:
3822:
3819:
3816:
3814:
3812:
3809:
3807:
3805:
3797:
3784:
3783:
3772:
3742:
3741:
3737:
3707:
3706:
3702:
3658:
3657:
3653:
3631:
3630:
3626:
3590:
3589:
3585:
3549:
3548:
3544:
3535:
3533:
3508:
3507:
3503:
3494:
3492:
3471:
3470:
3466:
3457:
3455:
3432:10.2307/2136122
3413:
3412:
3408:
3378:
3377:
3373:
3356:
3344:
3331:
3330:
3326:
3317:
3315:
3307:
3306:
3299:
3255:
3254:
3250:
3241:
3239:
3234:
3233:
3229:
3220:
3218:
3214:
3195:
3190:
3189:
3185:
3141:
3140:
3136:
3128:
3120:
3115:
3114:
3105:
3075:
3074:
3067:
3043:
3038:
3037:
3033:
3024:
3022:
3018:
3011:
3006:
3005:
2996:
2989:
2974:
2969:
2968:
2959:
2950:
2948:
2944:
2939:
2938:
2931:
2893:
2892:
2883:
2839:
2838:
2829:
2793:
2792:
2783:
2747:
2746:
2742:
2698:
2697:
2693:
2663:
2662:
2655:
2645:
2643:
2638:
2637:
2633:
2622:
2605:
2604:
2600:
2589:
2572:
2571:
2567:
2560:
2558:
2555:
2552:
2542:
2540:
2525:
2520:
2519:
2496:
2486:
2484:
2475:
2474:
2470:
2457:
2456:
2452:
2439:
2438:
2434:
2404:
2403:
2399:
2360:
2359:
2350:
2341:
2339:
2314:
2313:
2309:
2287:
2286:
2282:
2243:
2242:
2231:
2201:
2200:
2196:
2166:
2165:
2161:
2152:
2150:
2146:
2135:
2131:
2130:
2126:
2117:
2115:
2089:
2088:
2084:
2053:(1): CD001324.
2040:
2039:
2032:
2022:
2020:
2003:
2002:
1998:
1962:
1961:
1957:
1947:
1945:
1939:
1938:
1929:
1919:
1917:
1907:
1906:
1893:
1883:
1881:
1877:
1870:
1865:
1864:
1851:
1813:
1812:
1803:
1793:
1791:
1787:
1780:
1775:
1774:
1741:
1725:
1720:
1719:
1710:
1666:
1665:
1661:
1617:
1616:
1612:
1574:
1573:
1569:
1559:
1557:
1548:
1547:
1540:
1533:
1520:
1519:
1506:
1491:
1478:
1477:
1464:
1455:
1453:
1445:
1444:
1440:
1430:
1428:
1423:
1421:
1416:
1413:
1410:
1408:
1405:
1403:
1379:
1366:
1365:
1346:
1311:Pharmacotherapy
1308:
1307:
1303:
1259:
1258:
1249:
1205:
1204:
1195:
1190:
1173:
1102:
1090:
1084:
1020:
1000:
909:Yale University
894:
889:
864:calendar method
855:
800:A. Albert Yuzpe
769:
680:
671:
655:
629:
605:
593:anticonvulsants
589:enzyme-inducing
581:
473:
463:
420:
307:
291:
268:menstrual cycle
255:
203:
101:
52:
35:
28:
23:
22:
15:
12:
11:
5:
6655:
6653:
6645:
6644:
6639:
6629:
6628:
6622:
6621:
6618:
6617:
6615:
6614:
6609:
6604:
6599:
6597:Dydrogesterone
6594:
6589:
6584:
6578:
6576:
6572:
6571:
6569:
6568:
6563:
6558:
6553:
6547:
6545:
6541:
6540:
6538:
6537:
6529:
6524:
6519:
6514:
6509:
6501:
6492:
6490:
6486:
6485:
6483:
6482:
6477:
6472:
6467:
6461:
6459:
6451:
6450:
6448:
6447:
6442:
6440:Norelgestromin
6437:
6435:Levonorgestrel
6429:
6427:Norgestrienone
6424:
6415:
6413:
6409:
6408:
6406:
6405:
6400:
6395:
6390:
6385:
6380:
6375:
6370:
6364:
6362:
6351:
6345:
6344:
6342:
6341:
6336:
6331:
6326:
6321:
6316:
6311:
6306:
6301:
6295:
6293:
6287:
6286:
6284:
6283:
6278:
6273:
6268:
6259:
6257:
6251:
6250:
6245:
6243:
6242:
6235:
6228:
6220:
6211:
6210:
6208:
6207:
6201:
6199:
6195:
6194:
6191:
6190:
6188:
6187:
6182:
6176:
6174:
6166:
6165:
6163:
6162:
6157:
6152:
6147:
6141:
6139:
6128:
6124:
6123:
6121:
6120:
6115:
6109:
6107:
6101:
6100:
6098:
6097:
6092:
6087:
6085:Levonorgestrel
6082:
6077:
6071:
6069:
6061:
6060:
6058:
6057:
6052:
6047:
6042:
6037:
6031:
6029:
6023:
6022:
6019:
6018:
6016:
6015:
6009:
6007:
6001:
6000:
5998:
5997:
5992:
5987:
5981:
5979:
5973:
5972:
5970:
5969:
5964:
5959:
5954:
5949:
5943:
5941:
5930:
5924:
5923:
5921:
5920:
5914:
5911:Tubal ligation
5907:
5905:
5899:
5898:
5896:
5895:
5881:
5875:
5865:
5863:
5854:
5853:
5851:
5850:
5845:
5840:
5835:
5830:
5824:
5822:
5821:Related topics
5818:
5817:
5811:
5809:
5808:
5801:
5794:
5786:
5780:
5779:
5771:
5759:
5753:
5747:
5722:
5707:
5706:External links
5704:
5701:
5700:
5675:
5666:
5663:on 2022-05-02.
5637:
5605:
5584:
5567:
5556:. 29 June 2020
5541:
5515:
5473:
5454:
5428:
5401:
5369:
5337:
5299:
5278:
5253:
5246:
5222:
5215:
5197:
5178:
5159:
5140:
5133:
5108:
5089:
5067:
5048:
5027:
4986:
4967:(4): 562–563.
4951:
4932:(4): 243–247.
4915:
4872:
4837:
4816:
4791:
4745:
4724:
4704:
4701:on 2007-05-22.
4686:
4683:on 2004-02-27.
4656:
4609:
4584:
4563:
4520:
4509:(3): 127–128.
4493:
4466:
4439:(6): 266–270.
4423:
4388:
4350:
4339:(4): 3. 1967.
4323:
4294:
4268:
4253:on May 3, 2012
4228:
4170:
4077:
4055:
4006:
3984:
3938:
3935:. p. A14.
3900:
3876:
3853:
3830:
3806:Levonorgestrel
3795:
3770:
3751:(4): 228–229.
3735:
3700:
3651:
3624:
3583:
3542:
3501:
3464:
3406:
3387:(6): 549–558.
3371:
3343:978-1732055605
3342:
3324:
3297:
3268:(4): 335–344.
3248:
3227:
3183:
3134:
3103:
3065:
3054:(RR-4): 1–86.
3031:
2994:
2987:
2957:
2929:
2902:(3): 180–189.
2881:
2827:
2781:
2760:(4): 341–348.
2740:
2711:(2): 118–124.
2691:
2672:(4): 376–381.
2653:
2631:
2628:on 2009-01-13.
2620:
2598:
2595:on 2009-01-13.
2587:
2565:
2494:
2468:
2450:
2432:
2413:(6): 439–446.
2397:
2348:
2307:
2280:
2229:
2210:(4): 259–265.
2194:
2175:(3): 147–151.
2159:
2124:
2102:(4): 707–714.
2082:
2030:
2007:(March 2013).
1996:
1975:(4): 203–210.
1955:
1927:
1891:
1849:
1801:
1739:
1708:
1659:
1610:
1583:(6): 683–689.
1567:
1538:
1531:
1504:
1490:978-1732055605
1489:
1462:
1438:
1377:
1344:
1317:(2): 158–168.
1301:
1247:
1218:(4): 741–750.
1192:
1191:
1189:
1186:
1185:
1184:
1179:
1172:
1169:
1144:contraceptives
1128:cases such as
1101:
1098:
1086:Main article:
1083:
1080:
1079:
1078:
1074:
1043:
1039:
1032:
1028:
1025:levonorgestrel
1019:
1016:
1015:
1014:
1011:
999:
996:
995:
994:
993:
992:
986:
978:
964:
957:
952:In late 1973,
950:
942:
922:
893:
890:
888:
885:
854:
851:
785:rhesus macaque
775:and biologist
768:
765:
718:New York Times
679:
676:
670:
667:
654:
651:
633:levonorgestrel
628:
625:
604:
601:
585:St John's wort
580:
577:
525:pregnancy test
493:abdominal pain
462:
459:
449:most regimes.
419:
416:
311:levonorgestrel
306:
303:
290:
287:
254:
251:
205:
204:
202:
201:
198:
195:
192:
189:
185:
182:
181:
177:
176:
175:As per methods
173:
169:
168:
165:
161:
160:
157:
153:
152:
149:
142:
141:
137:
136:
133:
129:
128:
125:
124:User reminders
121:
120:
116:
115:
108:
104:
103:
98:
94:
93:
89:
88:
85:
79:
78:
75:
71:
70:
63:
59:
58:
54:
53:
50:
42:
41:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
6654:
6643:
6640:
6638:
6635:
6634:
6632:
6613:
6610:
6608:
6605:
6603:
6600:
6598:
6595:
6593:
6590:
6588:
6585:
6583:
6580:
6579:
6577:
6575:Miscellaneous
6573:
6567:
6564:
6562:
6559:
6557:
6554:
6552:
6549:
6548:
6546:
6542:
6536:
6533:
6530:
6528:
6525:
6523:
6520:
6518:
6515:
6513:
6510:
6508:
6505:
6504:Norpregnanes:
6502:
6500:
6497:
6494:
6493:
6491:
6487:
6481:
6478:
6476:
6473:
6471:
6468:
6466:
6463:
6462:
6460:
6457:
6452:
6446:
6443:
6441:
6438:
6436:
6433:
6430:
6428:
6425:
6423:
6420:
6417:
6416:
6414:
6410:
6404:
6401:
6399:
6396:
6394:
6391:
6389:
6386:
6384:
6381:
6379:
6376:
6374:
6371:
6369:
6366:
6365:
6363:
6360:
6355:
6352:
6350:
6346:
6340:
6337:
6335:
6332:
6330:
6327:
6325:
6322:
6320:
6317:
6315:
6312:
6310:
6307:
6305:
6302:
6300:
6297:
6296:
6294:
6292:
6288:
6282:
6279:
6277:
6274:
6272:
6269:
6267:
6264:
6261:
6260:
6258:
6256:
6252:
6248:
6241:
6236:
6234:
6229:
6227:
6222:
6221:
6218:
6206:
6203:
6202:
6200:
6196:
6186:
6183:
6181:
6178:
6177:
6175:
6173:
6167:
6161:
6158:
6156:
6153:
6151:
6148:
6146:
6143:
6142:
6140:
6138:
6132:
6129:
6125:
6119:
6116:
6114:
6111:
6110:
6108:
6106:
6102:
6096:
6095:Yuzpe regimen
6093:
6091:
6088:
6086:
6083:
6081:
6078:
6076:
6073:
6072:
6070:
6066:
6062:
6056:
6053:
6051:
6048:
6046:
6043:
6041:
6038:
6036:
6033:
6032:
6030:
6028:
6024:
6014:
6011:
6010:
6008:
6006:
6002:
5996:
5993:
5991:
5988:
5986:
5983:
5982:
5980:
5978:
5974:
5968:
5965:
5963:
5960:
5958:
5955:
5953:
5950:
5948:
5945:
5944:
5942:
5940:
5934:
5931:
5929:
5925:
5918:
5915:
5912:
5909:
5908:
5906:
5904:
5903:Sterilization
5900:
5893:
5889:
5885:
5882:
5879:
5876:
5874:
5870:
5867:
5866:
5864:
5861:
5860:contraception
5855:
5849:
5846:
5844:
5841:
5839:
5836:
5834:
5831:
5829:
5826:
5825:
5823:
5819:
5814:
5813:Birth control
5807:
5802:
5800:
5795:
5793:
5788:
5787:
5784:
5778:
5775:
5772:
5770:
5767:
5763:
5760:
5757:
5754:
5751:
5748:
5745:
5741:
5737:
5733:
5729:
5726:
5723:
5720:
5716:
5713:
5710:
5709:
5705:
5689:
5685:
5679:
5676:
5670:
5667:
5659:
5652:
5646:
5644:
5642:
5638:
5626:
5622:
5616:
5614:
5612:
5610:
5606:
5601:
5595:
5593:
5591:
5589:
5585:
5580:
5574:
5572:
5568:
5555:
5551:
5545:
5542:
5530:
5526:
5519:
5516:
5504:
5491:
5487:
5480:
5478:
5474:
5469:
5465:
5458:
5455:
5444:on 2018-11-03
5443:
5439:
5432:
5429:
5418:
5417:
5412:
5405:
5402:
5391:on 2006-10-11
5390:
5386:
5385:
5380:
5373:
5370:
5355:
5348:
5341:
5338:
5327:on 2006-10-11
5323:
5319:
5318:
5310:
5303:
5300:
5289:on 2006-11-21
5285:
5281:
5275:
5271:
5264:
5257:
5254:
5249:
5243:
5239:
5235:
5234:
5226:
5223:
5218:
5212:
5208:
5201:
5198:
5193:
5189:
5188:FDA Drug Bull
5182:
5179:
5174:
5170:
5163:
5160:
5156:(25): 5351–5.
5155:
5151:
5144:
5141:
5136:
5130:
5125:
5124:
5115:
5113:
5109:
5104:
5100:
5093:
5090:
5085:
5081:
5074:
5072:
5068:
5063:
5059:
5052:
5049:
5044:
5036:
5034:
5032:
5028:
5023:
5019:
5014:
5009:
5005:
5001:
4997:
4990:
4987:
4982:
4978:
4974:
4970:
4966:
4962:
4955:
4952:
4947:
4943:
4939:
4935:
4931:
4927:
4926:Contraception
4919:
4916:
4911:
4907:
4903:
4899:
4895:
4891:
4887:
4883:
4876:
4873:
4868:
4864:
4860:
4856:
4852:
4848:
4841:
4838:
4827:
4820:
4817:
4806:. Oct 9, 2020
4805:
4801:
4795:
4792:
4787:
4783:
4779:
4775:
4771:
4767:
4763:
4759:
4755:
4749:
4746:
4734:
4728:
4725:
4719:
4715:
4708:
4705:
4700:
4696:
4690:
4687:
4679:
4675:
4674:
4666:
4660:
4657:
4652:
4648:
4644:
4640:
4636:
4632:
4628:
4624:
4620:
4613:
4610:
4599:on 2006-09-28
4598:
4594:
4588:
4585:
4573:
4567:
4564:
4559:
4555:
4551:
4547:
4543:
4539:
4535:
4531:
4524:
4521:
4516:
4512:
4508:
4504:
4497:
4494:
4489:
4485:
4481:
4477:
4470:
4467:
4462:
4458:
4454:
4450:
4446:
4442:
4438:
4434:
4427:
4424:
4419:
4415:
4411:
4407:
4403:
4399:
4392:
4389:
4384:
4380:
4376:
4372:
4368:
4364:
4357:
4355:
4351:
4346:
4342:
4338:
4334:
4327:
4324:
4312:
4308:
4304:
4298:
4295:
4291:
4283:
4279:
4272:
4269:
4265:
4249:
4242:
4238:
4232:
4229:
4225:
4221:
4215:
4211:
4206:
4201:
4197:
4193:
4189:
4185:
4181:
4174:
4171:
4158:
4154:
4139:
4135:
4131:
4125:
4110:
4106:
4092:
4088:
4081:
4078:
4074:
4070:
4066:
4059:
4056:
4052:
4024:
4020:
4016:
4010:
4007:
4003:
3995:
3988:
3985:
3981:
3968:
3964:
3960:
3954:
3949:
3942:
3939:
3934:
3930:
3923:. p. A1.
3922:
3918:
3911:
3909:
3907:
3905:
3901:
3896:
3892:
3885:
3883:
3881:
3877:
3873:
3856:
3850:
3846:
3839:
3837:
3835:
3831:
3827:
3823:Other methods
3798:
3792:
3788:
3781:
3779:
3777:
3775:
3771:
3766:
3762:
3758:
3754:
3750:
3746:
3739:
3736:
3731:
3727:
3723:
3719:
3715:
3711:
3704:
3701:
3696:
3692:
3687:
3682:
3678:
3674:
3670:
3666:
3662:
3655:
3652:
3647:
3643:
3639:
3635:
3628:
3625:
3620:
3616:
3611:
3606:
3602:
3598:
3594:
3587:
3584:
3579:
3575:
3570:
3565:
3561:
3557:
3553:
3546:
3543:
3532:on 2018-07-04
3531:
3527:
3523:
3519:
3515:
3511:
3505:
3502:
3491:on 2018-07-19
3490:
3486:
3482:
3478:
3474:
3468:
3465:
3454:on 2007-03-13
3453:
3449:
3445:
3441:
3437:
3433:
3429:
3425:
3421:
3417:
3410:
3407:
3402:
3398:
3394:
3390:
3386:
3382:
3381:Contraception
3375:
3372:
3367:
3361:
3353:
3349:
3345:
3339:
3335:
3328:
3325:
3314:
3310:
3304:
3302:
3298:
3293:
3289:
3284:
3279:
3275:
3271:
3267:
3263:
3259:
3252:
3249:
3237:
3231:
3228:
3217:on 2012-05-26
3213:
3209:
3205:
3201:
3194:
3187:
3184:
3179:
3175:
3170:
3165:
3161:
3157:
3153:
3149:
3145:
3138:
3135:
3131:
3119:
3112:
3110:
3108:
3104:
3099:
3095:
3091:
3087:
3083:
3079:
3072:
3070:
3066:
3061:
3057:
3053:
3049:
3042:
3035:
3032:
3021:on 2016-03-03
3017:
3010:
3003:
3001:
2999:
2995:
2990:
2984:
2980:
2973:
2966:
2964:
2962:
2958:
2943:
2936:
2934:
2930:
2925:
2921:
2917:
2913:
2909:
2905:
2901:
2897:
2890:
2888:
2886:
2882:
2877:
2873:
2868:
2863:
2859:
2855:
2851:
2847:
2843:
2836:
2834:
2832:
2828:
2823:
2819:
2814:
2809:
2805:
2801:
2797:
2790:
2788:
2786:
2782:
2777:
2773:
2768:
2763:
2759:
2755:
2751:
2744:
2741:
2736:
2732:
2727:
2722:
2718:
2714:
2710:
2706:
2705:Contraception
2702:
2695:
2692:
2687:
2683:
2679:
2675:
2671:
2667:
2666:Contraception
2660:
2658:
2654:
2642:. Mayo Clinic
2641:
2635:
2632:
2627:
2623:
2617:
2613:
2609:
2602:
2599:
2594:
2590:
2584:
2580:
2576:
2569:
2566:
2562:
2539:
2535:
2531:
2524:
2517:
2515:
2513:
2511:
2509:
2507:
2505:
2503:
2501:
2499:
2495:
2482:
2478:
2472:
2469:
2464:
2460:
2454:
2451:
2446:
2442:
2436:
2433:
2428:
2424:
2420:
2416:
2412:
2408:
2407:Contraception
2401:
2398:
2393:
2389:
2385:
2381:
2377:
2373:
2369:
2365:
2357:
2355:
2353:
2349:
2338:on 2007-04-22
2337:
2333:
2329:
2325:
2321:
2318:/HRP (1999).
2317:
2311:
2308:
2303:
2299:
2295:
2291:
2284:
2281:
2276:
2272:
2268:
2264:
2260:
2256:
2252:
2248:
2240:
2238:
2236:
2234:
2230:
2225:
2221:
2217:
2213:
2209:
2205:
2204:Contraception
2198:
2195:
2190:
2186:
2182:
2178:
2174:
2170:
2169:Contraception
2163:
2160:
2149:on 2007-01-24
2145:
2141:
2134:
2128:
2125:
2114:on 2007-09-29
2113:
2109:
2105:
2101:
2097:
2093:
2086:
2083:
2078:
2074:
2069:
2064:
2060:
2056:
2052:
2048:
2044:
2037:
2035:
2031:
2018:
2014:
2010:
2006:
2000:
1997:
1992:
1988:
1983:
1978:
1974:
1970:
1966:
1959:
1956:
1943:
1940:ECEC (2014).
1936:
1934:
1932:
1928:
1915:
1911:
1908:ICEC (2014).
1904:
1902:
1900:
1898:
1896:
1892:
1876:
1869:
1862:
1860:
1858:
1856:
1854:
1850:
1845:
1841:
1837:
1833:
1829:
1825:
1821:
1817:
1810:
1808:
1806:
1802:
1786:
1779:
1772:
1770:
1768:
1766:
1764:
1762:
1760:
1758:
1756:
1754:
1752:
1750:
1748:
1746:
1744:
1740:
1735:
1731:
1724:
1717:
1715:
1713:
1709:
1704:
1700:
1695:
1690:
1686:
1682:
1678:
1674:
1670:
1663:
1660:
1655:
1651:
1646:
1641:
1637:
1633:
1629:
1625:
1624:Contraception
1621:
1614:
1611:
1606:
1602:
1598:
1594:
1590:
1586:
1582:
1578:
1571:
1568:
1555:
1551:
1545:
1543:
1539:
1534:
1528:
1524:
1517:
1515:
1513:
1511:
1509:
1505:
1500:
1496:
1492:
1486:
1482:
1475:
1473:
1471:
1469:
1467:
1463:
1452:
1448:
1442:
1439:
1435:
1433:
1426:
1419:
1396:
1392:
1388:
1384:
1380:
1374:
1370:
1363:
1361:
1359:
1357:
1355:
1353:
1351:
1349:
1345:
1340:
1336:
1332:
1328:
1324:
1320:
1316:
1312:
1305:
1302:
1297:
1293:
1288:
1283:
1279:
1275:
1271:
1267:
1263:
1256:
1254:
1252:
1248:
1243:
1239:
1234:
1229:
1225:
1221:
1217:
1213:
1209:
1202:
1200:
1198:
1194:
1187:
1183:
1180:
1178:
1175:
1174:
1170:
1168:
1165:
1159:
1156:
1151:
1149:
1145:
1141:
1140:sterilization
1136:
1133:
1132:
1127:
1123:
1119:
1115:
1114:
1113:Doe v. Bolton
1109:
1108:
1100:United States
1099:
1097:
1095:
1089:
1081:
1077:prescription.
1075:
1072:
1068:
1064:
1060:
1056:
1052:
1048:
1044:
1040:
1037:
1033:
1029:
1026:
1022:
1021:
1017:
1012:
1008:
1007:
1002:
1001:
997:
990:
989:
987:
983:
979:
975:
970:
965:
962:
961:generic drugs
958:
955:
951:
948:
943:
940:
936:
931:
927:
923:
920:
916:
915:
910:
906:
902:
901:
896:
895:
891:
887:United States
886:
884:
880:
875:
873:
869:
868:breastfeeding
865:
859:
852:
850:
846:
843:
841:
837:
833:
832:United States
829:
825:
821:
816:
813:
807:
805:
801:
796:
794:
789:
786:
782:
778:
774:
766:
764:
762:
758:
754:
749:
746:
742:
738:
733:
730:
728:
724:
720:
719:
714:
709:
706:
702:
698:
694:
690:
686:
677:
675:
668:
666:
664:
659:
652:
650:
648:
643:
641:
636:
634:
631:One brand of
626:
624:
620:
618:
614:
610:
602:
600:
598:
594:
590:
586:
578:
576:
574:
569:
567:
563:
559:
558:breast cancer
555:
550:
548:
544:
539:
537:
533:
528:
526:
522:
516:
514:
510:
506:
502:
498:
494:
489:
487:
482:
478:
472:
468:
460:
458:
456:
450:
446:
444:
439:
435:
430:
426:
423:
418:Effectiveness
417:
415:
412:
411:off-label use
408:
403:
401:
397:
393:
389:
385:
381:
376:
374:
369:
367:
363:
358:
356:
350:
348:
347:Yuzpe regimen
344:
340:
336:
332:
328:
324:
320:
316:
315:antiprogestin
312:
304:
302:
300:
296:
288:
286:
284:
279:
277:
273:
269:
265:
260:
259:birth control
252:
250:
248:
244:
242:
241:fertilization
238:
234:
229:
227:
223:
219:
218:birth control
215:
211:
199:
196:
193:
190:
187:
186:
183:
180:Medical notes
178:
174:
170:
166:
162:
158:
154:
150:
147:
143:
138:
134:
132:Clinic review
130:
126:
122:
117:
113:
109:
105:
102:IUD: under 1%
99:
95:
90:
86:
84:
80:
76:
72:
68:
64:
60:
55:
48:
43:
38:
33:
19:
6612:Proligestone
6607:Progesterone
6582:Mifepristone
6556:Medrogestone
6535:Drospirenone
6531:
6527:Trimegestone
6522:Promegestone
6503:
6495:
6480:Norgestimate
6470:Etonogestrel
6455:
6431:
6418:
6403:Quingestanol
6398:Noretynodrel
6358:
6349:Progestogens
6339:Ormeloxifene
6262:
6198:Experimental
6045:Cervical cap
6013:Ormeloxifene
5995:Vaginal ring
5967:Vaginal ring
5873:Hormonal IUD
5765:
5692:. Retrieved
5690:. 2005-07-28
5687:
5678:
5669:
5658:the original
5629:. Retrieved
5627:. 2016-03-14
5624:
5558:. Retrieved
5553:
5544:
5532:. Retrieved
5528:
5518:
5507:. Retrieved
5493:. Retrieved
5489:
5467:
5457:
5446:. Retrieved
5442:the original
5431:
5420:. Retrieved
5414:
5404:
5393:. Retrieved
5389:the original
5382:
5372:
5361:. Retrieved
5354:the original
5340:
5329:. Retrieved
5322:the original
5315:
5302:
5291:. Retrieved
5284:the original
5269:
5256:
5232:
5225:
5206:
5200:
5191:
5187:
5181:
5172:
5168:
5162:
5153:
5149:
5143:
5122:
5102:
5098:
5092:
5083:
5079:
5061:
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