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Chattopadhyay M, Kodela R, Olson KR, Kashfi K (March 2012). "NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model".
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cell lines, were effective in inhibiting the growth of these cell lines. NOSH-1 was also devoid of any cellular toxicity, and was comparable to aspirin in its
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Chemical structure of NOSH-Aspirin, with highlighted acetylsalicylic acid (green), sulfide-releasing (yellow), and nitric oxide-releasing (blue) groups.
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109:"NOSH-Aspirin: A Novel Nitric Oxide–Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals"
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S)- releasing areas. Preliminary studies have found that four NOSH variants, evaluated in eleven different human
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Kodela, Ravinder; Chattopadhyay, Mitali; Kashfi, Khosrow (8 March 2012).
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