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for a nested gene differs greatly from the coding sequence for its external host gene. Typically, nested genes and their host genes encode functionally unrelated proteins, and have different
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contains a relatively high proportion of nested intronic genes. It is predicted to contain at least 158 functional intronic nested genes, with an additional 212
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genomes. As with intronic nested genes, nonintronic nested genes typically do not share functions or expression patterns with their host genes.
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Genes nested opposite the coding sequences of their host genes are very rare, and have been observed in
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75:. Because only eukaryotic DNA contains intronic regions, this type of gene does not occur in
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genes nested in intronic regions. These genes seem to be distributed randomly across all
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of a larger gene, and occurs relatively frequently, especially in the introns of
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Yu P.; Ma D.; Xu M. (October 2005). "Nested genes in the human genome".
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whose entire coding sequence lies within the bounds (between the
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126:. These non-intronic nested genes remain to be identified in
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genes which lie opposite the coding sequence of a larger gene
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180:"An Overview of Nested Genes in Eukaryotic Genomes"
63:A nested intronic gene lies within the non-coding
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43:There are two categories of nested genes:
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106:Genes nested opposite coding sequences
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32:) of a larger external gene. The
114:, and more recently, in yeast (
178:Kumar, Anuj (September 2009).
1:
242:10.1016/j.ygeno.2005.06.008
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374:Sister chromatid exchange
369:Horizontal gene transfer
299:homologous recombination
303:mobile genetic elements
123:Tetrahymena thermophila
47:genes nested within an
354:Chromosomal crossover
59:Nested intronic genes
155:Alternative splicing
196:10.1128/EC.00143-09
38:expression patterns
433:Molecular genetics
428:Molecular biology
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140:Overlapping gene
51:of a larger gene
40:in an organism.
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397:Antigenic shift
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359:Gene conversion
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184:Eukaryotic Cell
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65:intronic region
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34:coding sequence
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330:Transformation
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260:External links
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190:(9): 1321–29.
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236:(4): 414–22.
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117:S. cerevisiae
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402:Reassortment
349:Transfection
325:Transduction
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150:RNA splicing
145:Genetic code
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88:human genome
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15:
407:Viral shift
364:Fusion gene
320:Conjugation
312:prokaryotic
112:prokaryotes
100:chromosomes
92:pseudogenes
71:and higher
26:start codon
18:nested gene
422:Categories
379:Transposon
341:eukaryotes
339:Occurs in
310:Primarily
161:References
94:and three
73:eukaryotes
30:stop codon
120:) and in
69:metazoans
295:Genetics
250:16084061
230:Genomics
214:19542305
134:See also
128:metazoan
77:bacteria
28:and the
205:2747821
81:archaea
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96:snoRNA
49:intron
389:Viral
20:is a
246:PMID
210:PMID
86:The
22:gene
238:doi
200:PMC
192:doi
79:or
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301:/
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234:86
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168:^
83:.
16:A
287:e
280:t
273:v
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188:8
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