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The eye findings of
Parinaud's syndrome generally improve slowly over months, especially with resolution of the causative factor; continued resolution after the first 3–6 months of onset is uncommon. However, rapid resolution after normalization of intracranial pressure following placement of a
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234:
should elevate the eyes, but eventually all upward gaze mechanisms fail. In the extreme form, conjugate down gaze in the primary position, or the "setting-sun sign" is observed. Neurosurgeons see this sign most commonly in patients with hydrocephalus.
782:
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249:: Attempts at upward gaze often produce this phenomenon. On fast up-gaze, the eyes pull in and the globes retract. The easiest way to bring out this reaction is to ask the patient to follow down-going stripes on an
192:
840:
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422:
Diagnosis can be made via combination of physical exam, particularly deficits of the relevant cranial nerves. Confirmation can be made via imaging, such as CT scan or MRI.
153:
Dorsal midbrain syndrome, vertical gaze palsy, upward gaze palzy, sunset sign, setting-sun sign, sun-setting sign, sunsetting sign, sunset eye sign, setting-sun phenomenon
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is a constellation of neurological signs indicating injury to the dorsal midbrain. More specifically, compression of the vertical gaze center at the
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is essential to rule out anatomic lesions or other causes of this syndrome. Visually significant upgaze palsy can be relieved with bilateral
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Treatment is primarily directed towards etiology of the dorsal midbrain syndrome. A thorough workup, including
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recessions. Retraction nystagmus and convergence movement are usually improved with this procedure as well.
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Parinaud's syndrome is a cluster of abnormalities of eye movement and pupil dysfunction, characterized by:
1273:
1227:
1098:
1006:
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199:
633:
H. Parinaud. Paralysie des mouvements associés des yeux. Archives de neurologie, Paris, 1883, 5: 145-172.
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279:) or slower movements of the abducting eye than the adducting eye during horizontal saccades, see-saw
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Aguilar-Rebolledo F, Zárate-Moysén A, Quintana-Roldán G (1998). "Parinaud's syndrome in children".
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Waga S, Okada M, Yamamoto Y (1979). "Reversibility of
Parinaud syndrome in thalamic hemorrhage".
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398:
Vertical supranuclear ophthalmoplegia has also been associated with metabolic disorders, such as
366:
379:
However, any other compression, ischemia or damage to this region can produce these phenomena:
242:: Accommodative paresis ensues, and pupils become mid-dilated and show light-near dissociation.
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Paralysis of upwards gaze: Downward gaze is usually preserved. This vertical palsy is
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Parinaud's syndrome results from injury, either direct or compressive, to the dorsal
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MPH, Eudocia Quant Lee, MD; MD, David Schiff; MD, Patrick Y. Wen (2011-09-28).
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315:. The area affected in Parinaud's syndrome is indicated by the striped region.
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Disorders of ocular muscles, binocular movement, accommodation and refraction
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on attempted upward gaze, pseudoabducens palsy (also known as thalamic
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594:"Sunset eye sign | Radiology Reference Article | Radiopaedia.org"
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Biglan, Albert W. (January 1984). "Setting Sun Sign in
Infants".
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Waterston, Tony; Helms, Peter; Ward-Platt, Martin (2016-07-06).
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nuclei, causing dysfunction to the motor function of the eye.
193:
rostral interstitial nucleus of medial longitudinal fasciculus
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Classically, it has been associated with three major groups:
470:
565:
Paediatrics: A Core Text on Child Health, Second
Edition
323:. Specifically, compression or ischemic damage of the
473:. Springer Science & Business Media. p. 202.
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have also been associated with the midbrain syndrome.
1117:
Upper dorsal pontine syndrome/Raymond–Céstan syndrome
271:. It has less commonly been associated with spasm of
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210:(1844–1905), considered to be the father of French
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67:. Unsourced material may be challenged and removed.
283:and associated ocular motility deficits including
391:infection. Neoplasms and giant aneurysms of the
267:It is also commonly associated with bilateral
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8:
547:: CS1 maint: multiple names: authors list (
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524:Neurologic Complications of Cancer Therapy
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527:. Demos Medical Publishing. p. 383.
127:Learn how and when to remove this message
459:
1284:Syndromes affecting the nervous system
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27:Inability to move the eyes up and down
1082:Lateral medullary syndrome/Wallenberg
7:
65:adding citations to reliable sources
385:cerebral arteriovenous malformation
1094:Medial medullary syndrome/Dejerine
655:"Convergence-retraction nystagmus"
198:It is a group of abnormalities of
32:Parinaud's oculoglandular syndrome
25:
41:
863:associated with lesions of the
52:needs additional citations for
508:10.1080/0065955X.1984.11981637
1:
206:dysfunction and is named for
1155:Internuclear ophthalmoplegia
643:Neuro-Ophthalmic Examination
365:Women in their 20s-30s with
297:internuclear ophthalmoplegia
1300:
568:. CRC Press. p. 149.
496:American Orthoptic Journal
449:ventriculoperitoneal shunt
29:
1253:Upper motor neuron lesion
371:Older patients following
157:
18:Nothnagel's syndrome
1122:Lateral pontine syndrome
30:Not to be confused with
1160:One and a half syndrome
1136:Millard–Gubler syndrome
1132:Medial pontine syndrome
387:, trauma and brainstem
383:, midbrain hemorrhage,
362:, causing hydrocephalus
245:Convergence-retraction
240:Argyll Robertson pupils
1228:Alternating hemiplegia
467:Larner, A. J. (2001).
375:of the upper brainstem
327:tectum, including the
316:
310:
76:"Parinaud's syndrome"
722:10.1212/wnl.29.3.407
665:on 14 September 2016
400:Niemann-Pick disease
350:Young patients with
232:doll's head maneuver
61:improve this article
1248:Pseudobulbar affect
1202:Parinaud's syndrome
1193:ventral tegmentum,
1007:Parkinson's disease
926:Hemispatial neglect
451:has been reported.
329:superior colliculus
189:Parinaud's syndrome
145:Parinaud's syndrome
1180:ventral peduncle,
1150:Locked-in syndrome
1140:Foville's syndrome
1040:Dysdiadochokinesia
951:Cortical blindness
931:Gerstmann syndrome
906:Expressive aphasia
857:Signs and symptoms
689:Rev. Invest. Clin.
367:multiple sclerosis
317:
218:Signs and symptoms
1261:
1260:
1236:
1235:
1212:Claude's syndrome
1189:Benedikt syndrome
1055:Cerebellar ataxia
1014:Thalamic syndrome
971:Cortical deafness
946:Bálint's syndrome
921:Receptive aphasia
823:
822:
592:Gaillard, Frank.
575:978-1-138-03131-9
534:978-1-61705-019-0
480:978-1-4020-0042-3
311:Cross section of
186:
185:
139:Medical condition
137:
136:
129:
111:
16:(Redirected from
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1176:Weber's syndrome
1072:
1045:Intention tremor
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843:
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661:. Archived from
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404:Wilson's disease
341:Edinger-Westphal
289:oculomotor nerve
251:optokinetic drum
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942:Occipital lobe
876:Cerebral cortex
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681:Further reading
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393:posterior fossa
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293:trochlear nerve
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993:Basal ganglia
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967:Temporal lobe
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956:Anton syndrome
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917:Parietal lobe
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754:Classification
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746:External links
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691:(in Spanish).
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502:(1): 114–116.
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285:skew deviation
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261:Collier's sign
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208:Henri Parinaud
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1274:Medical signs
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976:Prosopagnosia
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936:Astereognosis
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902:Frontal lobe
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695:(3): 217–20.
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623:Who Named It?
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389:toxoplasmosis
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381:hydrocephalus
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337:cranial nerve
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325:mesencephalic
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273:accommodation
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212:ophthalmology
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117:February 2015
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78: –
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73:
72:Find sources:
66:
62:
56:
55:
50:This article
48:
44:
39:
38:
33:
19:
1201:
893:PCA syndrome
888:MCA syndrome
883:ACA syndrome
807:
796:
781:
766:
716:(3): 407–9.
713:
709:
692:
688:
667:. Retrieved
663:the original
658:
649:
638:
629:
616:
612:
601:. Retrieved
597:
564:
557:
523:
516:
499:
495:
489:
469:
462:
445:
432:neuroimaging
429:
421:
397:
378:
356:pineal gland
352:brain tumors
345:
318:
266:
259:retraction (
228:supranuclear
221:
200:eye movement
197:
188:
187:
123:
114:
104:
97:
90:
83:
71:
59:Please help
54:verification
51:
1128:) (lateral)
961:Pure alexia
659:www.aao.org
598:Radiopaedia
412:barbiturate
408:kernicterus
335:(origin of
269:papilledema
150:Other names
1268:Categories
1024:Cerebellum
809:DiseasesDB
603:2020-01-05
455:References
414:overdose.
333:oculomotor
295:palsy and
87:newspapers
1067:Brainstem
1035:Dysmetria
987:Subcortex
869:brainstem
861:syndromes
710:Neurology
618:synd/1906
543:cite book
442:Prognosis
426:Treatment
418:Diagnosis
339:III) and
331:adjacent
281:nystagmus
277:esotropia
247:nystagmus
195:(riMLF).
173:Neurology
168:Specialty
1169:Midbrain
1031:Lateral
1002:Dystonia
738:42247406
669:17 March
360:midbrain
321:midbrain
313:midbrain
1144:basilar
1075:Medulla
1051:Medial
898:Aphasia
803:D015835
701:9763886
354:in the
291:palsy,
238:Pseudo-
101:scholar
997:Chorea
911:Abulia
859:, and
792:378.81
736:
730:571990
728:
699:
572:
531:
477:
410:, and
373:stroke
303:Causes
257:Eyelid
175:
103:
96:
89:
82:
74:
1241:Other
1221:Other
865:brain
814:32982
777:G46.3
734:S2CID
230:, so
204:pupil
108:JSTOR
94:books
1126:AICA
1110:Pons
1087:PICA
867:and
798:MeSH
787:9-CM
726:PMID
697:PMID
671:2020
570:ISBN
549:link
529:ISBN
475:ISBN
202:and
80:news
1195:PCA
1182:PCA
1099:ASA
783:ICD
768:ICD
718:doi
621:at
504:doi
358:or
63:by
1270::
812::
801::
790::
775::
772:10
732:.
724:.
714:29
712:.
693:50
657:.
596:.
584:^
545:}}
541:{{
500:34
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402:,
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673:.
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506::
483:.
263:)
253:.
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124:(
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115:(
105:·
98:·
91:·
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