199:
MJ, Bhagani S, Ahn MY, Sanyal AJ, Huhn G, Marty FM; GS-US-540-5774 Investigators. Effect of
Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial. JAMA. 2020 Sep 15;324(11):1048-1057. doi: 10.1001/jama.2020.16349. PMID 32821939; PMCID: PMC7442954.
210:
Kambutse I, Igiraneza G, Ogbuagu O. Perceptions of HIV transmission and pre-exposure prophylaxis among health care workers and community members in Rwanda. PLoS One. 2018 Nov 26;13(11):e0207650. doi: 10.1371/journal.pone.0207650. Erratum in: PLoS One. 2019 Feb 22;14(2):e0212933. PMID 30475841; PMCID:
176:
In 2014 and in 2019, he received the Gerald H. Friedland prize for outstanding international research presentation by the
Connecticut Infectious Diseases Society. On February 18, 2020, he also received an award from the Rwanda College of Physicians for his contribution in the fight against infectious
23:
in New Haven, CT and is the director of the Yale AIDS Program clinical trials unit. His research contributions have focused on HIV/AIDS prevention and COVID-19 vaccination and treatment clinical trials. He switched his focus at the beginning of the 2019 COVID pandemic and participated as a principal
32:
SIMPLE trial in 2020 and 2021. In pursuit of his global health component of his career, Ogbuagu also supports postgraduate physician medical education programs in low and middle income countries in sub-Saharan Africa in Rwanda (2013–2018) and
Liberia (2017 to date) as well as HIV treatment programs
198:
Spinner CD, Gottlieb RL, Criner GJ, Arribas López JR, Cattelan AM, Soriano
Viladomiu A, Ogbuagu O, Malhotra P, Mullane KM, Castagna A, Chai LYA, Roestenberg M, Tsang OTY, Bernasconi E, Le Turnier P, Chang SC, SenGupta D, Hyland RH, Osinusi AO, Cao H, Blair C, Wang H, Gaggar A, Brainard DM, McPhail
142:
At the beginning of the COVID-19 pandemic, Ogbuagu shifted his focus from AIDS/HIV research and patient care to lead vaccine trials for COVID-19 at the Yale Center for
Clinical Investigation where he was a PI on the Pfizer-BioNtech COVID-19 mRNA vaccine trial arms at Yale in adults as well as the
190:
Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez JL, Pérez Marc G, Moreira ED, Zerbini C, Bailey R, Swanson KA, Roychoudhury S, Koury K, Li P, Kalina WV, Cooper D, Frenck RW Jr, Hammitt LL, Türeci Ö, Nell H, Schaefer A, Ünal S, Tresnan DB, Mather S, Dormitzer PR, Şahin U,
133:
since 2012, where he mentors medical residents and junior faculty and assists them in conducting clinical research projects that have local importance such as HIV/AIDS and antimicrobial resistance. In
Liberia, he is program director of Yale's Office of Global Health's efforts to support Internal
202:
Ogbuagu O, Marshall BDL, Tiberio P, Ogunbajo A, Barakat L, Montgomery M, Almonte A, Wray T, Williams EC, Edelman EJ, Chan PA. Prevalence and
Correlates of Unhealthy Alcohol and Drug Use Among Men Who Have Sex with Men Prescribed HIV Pre-exposure Prophylaxis in Real-World Clinical Settings. AIDS
194:
Edelman EJ, Moore BA, Calabrese SK, Berkenblit G, Cunningham CO, Ogbuagu O, Patel VV, Phillips KA, Tetrault JM, Shah M, Blackstock O. Preferences for implementation of HIV pre-exposure prophylaxis (PrEP): Results from a survey of primary care providers. Prev Med Rep. 2019 Oct 21;17:101012. doi:
110:
Ogbuagu is an HIV/AIDS physician and leads a clinical trials program at Yale that conducts research on infectious diseases. He has been the principal investigator on pharmacokinetic, phase 2 and 3 safety and efficacy trials of novel antiviral compounds for HIV in addition to his recent work on
93:
Ogbuagu completed an infectious diseases fellowship at Yale School of
Medicine in 2012 and assumed a faculty position as an assistant professor in the same year. Currently, he is an associate professor of medicine in the Department of Internal Medicine, Section of Infectious Diseases.
206:
Rutledge R, Madden L, Ogbuagu O, Meyer JP. HIV Risk perception and eligibility for pre-exposure prophylaxis in women involved in the criminal justice system. AIDS Care. 2018 Oct;30(10):1282-1289. doi: 10.1080/09540121.2018.1447079. Epub 2018 Mar 11. PMID 29527934; PMCID:
1065:
Spinner, Christoph D.; Gottlieb, Robert L.; Criner, Gerard J.; Arribas López, José Ramón; Cattelan, Anna Maria; Soriano
Viladomiu, Alex; Ogbuagu, Onyema; Malhotra, Prashant; Mullane, Kathleen M.; Castagna, Antonella; Chai, Louis Yi Ann (2020-09-15).
721:
Spinner, Christoph D.; Gottlieb, Robert L.; Criner, Gerard J.; Arribas López, José Ramón; Cattelan, Anna Maria; Soriano
Viladomiu, Alex; Ogbuagu, Onyema; Malhotra, Prashant; Mullane, Kathleen M.; Castagna, Antonella; Chai, Louis Yi Ann (2020-09-15).
424:
Spinner, Christoph D.; Gottlieb, Robert L.; Criner, Gerard J.; Arribas López, José Ramón; Cattelan, Anna Maria; Soriano Viladomiu, Alex; Ogbuagu, Onyema; Malhotra, Prashant; Mullane, Kathleen M.; Castagna, Antonella; Chai, Louis Yi Ann (2020-09-15).
186:
Tuan J, Spichler-Moffarah A, Ogbuagu O. A new positive SARS-CoV-2 test months after severe COVID-19 illness: reinfection or intermittent viral shedding? BMJ Case Rep. 2021 Feb 4;14(2):e240531. doi: 10.1136/bcr-2020-240531. PMID 33542020; PMCID:
191:
Jansen KU, Gruber WC; C4591001 Clinical Trial Group. Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine. N Engl J Med. 2020 Dec 31;383(27):2603-2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10. PMID 33301246; PMCID: PMC7745181.
258:
Sopeyin, Anuoluwapo; Hornsey, Emilio; Okwor, Tochi; Alimi, Yewande; Raji, Tajudeen; Mohammed, Abdulaziz; Moges, Hiwot; Onwuekwe, Ezinne V C.; Minja, Frank J.; Gon, Giorgia; Ogbuagu, Onyema; Ogunsola, Folasade; Paintsil, Elijah (2020).
64:, respectively, when their twins were born. The couple had graduated in the 1974 from the University of Nigeria, Nsukka, where Stella was valedictorian. The family returned to Nigeria when Onyema and Chibuzo were five years old.
968:
366:
Polack, Fernando P.; Thomas, Stephen J.; Kitchin, Nicholas; Absalon, Judith; Gurtman, Alejandra; Lockhart, Stephen; Perez, John L.; Pérez Marc, Gonzalo; Moreira, Edson D.; Zerbini, Cristiano; Bailey, Ruth (2020-12-31).
308:
Frenck, Robert W.; Klein, Nicola P.; Kitchin, Nicholas; Gurtman, Alejandra; Absalon, Judith; Lockhart, Stephen; Perez, John L.; Walter, Emmanuel B.; Senders, Shelly; Bailey, Ruth; Swanson, Kena A. (2021-07-15).
623:
44:. He has been a co-author on 43 scholarly articles, according to the National Library of Medicine. According to Google Scholar, one article he co-authored on Remdesivir and its use for Covid that appeared in
19:(born June 20, 1978) is an American-born infectious diseases physician, educator, researcher, and clinical trial investigator, who was raised and educated in Nigeria. He is an associate professor at
161:
Previous to this clinical trial work, he researched pharmacokinetic, phase 2 and 3 safety and efficacy trials of novel antiviral compounds (HIV), and conducted HIV prevention trials.
78:, and obtained his secondary education at Federal Government College, Okigwe, Imo State, Nigeria (1988 to1994), graduating at 15. He graduated from the College of Medical Sciences,
1174:
860:
Barakat, Lydia Aoun; Dunne, Dana W.; Tetrault, Jeanette M.; Soares, Sarita; Chia, David; Ogbuagu, Onyema E.; Moriarty, John P.; Huot, Stephen J.; Green, Michael L. (November 2018).
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pediatric studies for12-15 year-olds and 6 month to 11 year olds. The adult Pfizer BioNtech vaccine received emergency use authorization in the United States from the
1189:
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173:. In 2017, He received the Steve Huot Faculty Award for Dedication and Excellence from Yale School of Medicine's Internal Medicine Primary Care Program.
1194:
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novel COVID-19 vaccination candidate. He was also the Yale site PI for COVID treatment studies including the Remdesivir SIMPLE moderate and Severe trials.
553:
969:"Research by Young ISN Members Highlights the Importance of Sub-tertiary Hospital Capacity to Manage Kidney Disease in Low- and Middle-income Countries"
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787:
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261:"Transmission risk of respiratory viruses in natural and mechanical ventilation environments: Implications for SARS-CoV-2 transmission in Africa"
56:
Onyema Ogbuagu and an identical twin brother, Chibuzo Ogbuagu II, were born to Chibuzo and Stella Ogbuagu. Nigerian doctoral students attending
835:
1184:
943:
491:
25:
577:
1068:"Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial"
724:"Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial"
427:"Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial"
170:
86:
Teaching Hospital in Abakaliki, Nigeria. He then returned to the United States, where he interned at the Elmhurst campus of
130:
102:
Ogbuagu is married to Grace Igiraneza Ogbuagu. She is a nephrologist and member of the International Nephrology Society.
144:
673:
71:, Nigeria, and his mother was a professor of sociology and a former deputy vice-chancellor of the same institution.
61:
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was cited 504 times. Ogbuagu was selected as the commencement speaker for Yale School of Medicine's class of 2021.
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20:
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Julia Hollingsworth, Adam Renton, Emma Reynolds, Nada Bashir, Melissa Macaya and Meg Wagner (2020-12-10).
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He is a clinician at Yale Medicine, the medical practice of Yale School of Medicine, and sees patients at
79:
68:
1154:
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918:"Yale physician, daughter share message about COVID vaccination as pediatric hospitalizations surge"
147:
in 2020 and full FDA approval in 2021. There were approximately 150 sites for the Pfizer BioNtech
899:
862:"The Changing Face of HIV Care: Expanding HIV Training in an Internal Medicine Residency Program"
203:
Behav. 2019 Jan;23(1):190-200. doi: 10.1007/s10461-018-2260-9. PMID 30145707; PMCID: PMC7020905.
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600:"Large U.S. covid-19 vaccine trials are halfway enrolled, but lag on participant diversity"
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624:"Connecticut's Shot in the Arm: State leaders, health officials discuss COVID-19 vaccine"
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In his role as public health educator, he has worked to increase public understanding of
1017:
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Medicine residency training. He trained the first infectious disease fellow in Liberia.
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836:"PROFILE: Meet Onyema Ogbuagu, UNICAL graduate leading COVID-19 vaccine research in US"
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492:"Pfizer principal investigator "very optimistic" about positive news after FDA meeting"
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311:"Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents"
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788:"MD Class of 2021 Selects Associate Professor Onyema Ogbuagu as Commencement Speaker"
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1125:"COVID-19 Clinical Trials for Treatment and Prevention - Learning from Successes"
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812:"Meet Onyema Ogbuagu, di Nigerian inside Pfizer Covid-19 vaccine breakthrough"
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90:. Ogbuagu completed his residency and chief residency at Mount Sinai in 2010.
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Academic Medicine: Journal of the Association of American Medical Colleges
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554:"Low public trust could hurt vaccine distribution in minority communities"
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Onyema Ogbuagu attended Auntie Margaret International Primary School in
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Before their recent retirement, Onyema's father was vice-chancellor of
1018:"Onyema E. Ogbuagu, MD Infectious Disease of Yale New Haven Hospital"
126:
944:"Vaccine Clinic Offers Choice and Reassurance to New Haven Children"
530:"Video: What you need to know about COVID-19 vaccine distribution"
649:"T.D. Jakes Hosts Conversation with COVID-19 Vaccine Scientists"
45:
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10.1016/j.pmedr.2019.101012. PMID 31890474; PMCID: PMC6926349.
82:, Nigeria in 2014. He completed his medical internship at the
579:
New Pfizer trial shows vaccine 100% effective in teens 12-15
369:"Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine"
994:"Yale investigates potential treatments for COVID-19"
1129:Columbia Alumni Association of Fairfield County
674:"COVID Vaccines and the Return to Life: Part 1"
154:Ogbuagu was also a PI for the second Phase 2b
1175:Fellows of the American College of Physicians
151:trial, each led by a principal investigator.
8:
514:: CS1 maint: multiple names: authors list (
169:In 2015, Ogbuagu elected as a Fellow of the
698:"Onyema Ogbuagu - Search Results - PubMed"
129:. He has been a visiting professor to the
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1165:21st-century African-American scientists
111:COVID-19 vaccinations and therapeutics.
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88:Icahn School of Medicine at Mount Sinai
1190:American infectious disease physicians
598:Johnson, Carolyn Y. (27 August 2020).
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40:. Ogbuagu has also worked to decrease
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235:"Onyema Ogbuagu, MBBCh, FACP, FIDSA"
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1195:American people of Nigerian descent
973:International Society of Nephrology
373:The New England Journal of Medicine
315:The New England Journal of Medicine
145:Food and Drug Administration (FDA)
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1123:Nneji, Bernard (April 29, 2021).
28:COVID-19 vaccine trials and the
1170:21st-century American physicians
1210:21st-century American academics
1180:Yale School of Medicine faculty
992:Horowitch, Rose (2020-04-06).
171:American College of Physicians
138:COVID-19 and HIV/AIDS research
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131:National University of Rwanda
121:Ogbuagu trains physicians in
1185:University of Calabar alumni
967:Parmar, Reema (2020-05-12).
879:10.1097/ACM.0000000000002317
33:in Liberia (2018 to date).
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62:University of Pennsylvania
17:Onyema Eberechukwu Ogbuagu
277:10.1136/bmjgh-2020-003522
24:investigator (PI) on the
942:Lucci-Canapari, Jeanna.
156:Sanofi-Glaxo Smith Klein
118:'s Nathan Smith Clinic.
52:Early life and education
1084:10.1001/jama.2020.16349
740:10.1001/jama.2020.16349
443:10.1001/jama.2020.16349
116:Yale New Haven Hospital
84:Ebonyi State University
21:Yale School of Medicine
385:10.1056/NEJMoa2034577
327:10.1056/NEJMoa2107456
80:University of Calabar
69:Abia State University
678:The Aspen Institute
653:www.prnewswire.com
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265:BMJ Global Health
239:medicine.yale.edu
42:vaccine hesitancy
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1155:1978 births
211:PMC6261021.
207:PMC6085161.
187:PMC8098910.
1149:Categories
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1051:2021-06-17
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