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OpenBiome

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510: 135:. It is the first public stool bank, and was founded to facilitate use of FMT. The logistical burdens associated with screening and processing fecal material have made it difficult for clinicians to offer FMT to patients with recurrent 125:, a lower-concentration "FMP 250" for delivery via the lower gastrointestinal tract, and, as of October 2015, a capsule formulation. As of March 2017, OpenBiome had provided over 20,000 treatments to 50 states and 7 countries. 554: 128:
In 2015, OpenBiome announced the launch of PersonalBiome, a stool banking program through which individuals could store their stool for future use in fecal transplantation after microbial dysbiosis.
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Magill, SS; Edwards, JR; Bamberg, W; Beldavs, ZG; Dumyati, G; Kainer, MA; Lynfield, R; Maloney, M; McAllister-Hollod, L; Nadle, J; Ray, SM; Thompson, DL; Wilson, LE; Fridkin, SK (27 Mar 2014).
205: 320: 230: 544: 559: 121:(FMT) therapies. OpenBiome can provide clinicians with three different formulations: a high-concentration "FMP 30" formulation for delivery via the upper 539: 549: 426: 371: 421: 132: 245: 114: 131:
OpenBiome was founded in 2012 by Mark Smith, a microbiology student at MIT, and James Burgess, an MBA student at the
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in the U.S. OpenBiome provides frozen preparations of screened and filtered human stool for use in
438: 453: 406: 224: 186: 380: 176: 168: 92: 401: 534: 181: 156: 528: 416: 45: 448: 109: 411: 469: 396: 190: 172: 157:"Multistate point-prevalence survey of health care-associated infections" 104: 28: 349: 91:, which operates a public stool bank and supports research on the 353: 71: 344: 272:"Student-led Project Banks on Promise of Fecal Transplants" 555:
Medical and health organizations based in Massachusetts
483: 462: 387: 66: 54: 34: 24: 321:"Fecal transplant safety is goal of stool bank" 365: 8: 19: 244:Velasquez-Manoff, Moises (9 October 2015). 229:: CS1 maint: numeric names: authors list ( 372: 358: 350: 18: 246:"Opinion - Should We Bank Our Own Stool?" 180: 204:Gastroenterology, Healio; January 2017. 107:and clinics to support the treatment of 147: 222: 545:Health charities in the United States 7: 560:2012 establishments in Massachusetts 274:. The Chronicle for Higher Education 293:Smith, Peter Andrey (17 Feb 2014). 113:, the most common pathogen causing 103:OpenBiome distributes material to 14: 540:Organizations established in 2012 550:Charities based in Massachusetts 509: 508: 319:Johnson, Carolyn (24 Feb 2014). 119:fecal microbiota transplantation 295:"A New Kind of Transplant Bank" 87:is a nonprofit organization in 133:MIT Sloan School of Management 1: 270:Glenn, David (3 Feb 2014). 115:hospital-acquired infection 576: 504: 89:Somerville, Massachusetts 491:Human Microbiome Project 259:– via NYTimes.com. 463:Disorders and therapies 206:"Onsite with OpenBiome" 427:In bacterial vaginosis 123:gastrointestinal tract 16:Nonprofit organization 173:10.1056/NEJMoa1306801 21: 323:. The Boston Globe 299:The New York Times 250:The New York Times 522: 521: 167:(13): 1198–1208. 82: 81: 61:Carolyn Edelstein 567: 512: 511: 381:Human microbiota 374: 367: 360: 351: 345:Official Website 333: 332: 330: 328: 316: 310: 309: 307: 305: 290: 284: 283: 281: 279: 267: 261: 260: 258: 256: 241: 235: 234: 228: 220: 218: 216: 201: 195: 194: 184: 152: 93:human microbiome 78: 75: 73: 22: 575: 574: 570: 569: 568: 566: 565: 564: 525: 524: 523: 518: 500: 479: 475:Faecal transfer 458: 383: 378: 341: 336: 326: 324: 318: 317: 313: 303: 301: 292: 291: 287: 277: 275: 269: 268: 264: 254: 252: 243: 242: 238: 221: 214: 212: 203: 202: 198: 154: 153: 149: 145: 101: 70: 57: 50: 17: 12: 11: 5: 573: 571: 563: 562: 557: 552: 547: 542: 537: 527: 526: 520: 519: 517: 516: 505: 502: 501: 499: 498: 493: 487: 485: 481: 480: 478: 477: 472: 466: 464: 460: 459: 457: 456: 451: 446: 441: 436: 431: 430: 429: 424: 414: 409: 404: 399: 393: 391: 385: 384: 379: 377: 376: 369: 362: 354: 348: 347: 340: 339:External links 337: 335: 334: 311: 285: 262: 236: 210:www.healio.com 196: 146: 144: 141: 100: 97: 80: 79: 68: 64: 63: 58: 55: 52: 51: 49: 48: 38: 36: 32: 31: 26: 15: 13: 10: 9: 6: 4: 3: 2: 572: 561: 558: 556: 553: 551: 548: 546: 543: 541: 538: 536: 533: 532: 530: 515: 507: 506: 503: 497: 494: 492: 489: 488: 486: 482: 476: 473: 471: 468: 467: 465: 461: 455: 452: 450: 447: 445: 442: 440: 437: 435: 432: 428: 425: 423: 420: 419: 418: 415: 413: 410: 408: 405: 403: 400: 398: 395: 394: 392: 390: 386: 382: 375: 370: 368: 363: 361: 356: 355: 352: 346: 343: 342: 338: 322: 315: 312: 300: 296: 289: 286: 273: 266: 263: 251: 247: 240: 237: 232: 226: 211: 207: 200: 197: 192: 188: 183: 178: 174: 170: 166: 162: 158: 151: 148: 142: 140: 138: 134: 129: 126: 124: 120: 116: 112: 111: 106: 98: 96: 94: 90: 86: 77: 69: 65: 62: 59: 53: 47: 46:Massachusetts 43: 40: 39: 37: 33: 30: 27: 23: 495: 449:Human virome 422:In pregnancy 325:. Retrieved 314: 302:. Retrieved 298: 288: 276:. Retrieved 265: 253:. Retrieved 249: 239: 213:. Retrieved 209: 199: 164: 161:N Engl J Med 160: 150: 139:infections. 137:C. difficile 136: 130: 127: 110:C. difficile 108: 102: 84: 83: 389:Human flora 529:Categories 255:13 January 215:13 January 143:References 74:.openbiome 56:Key people 42:Somerville 496:OpenBiome 470:Dysbiosis 454:Mycobiota 105:hospitals 85:OpenBiome 20:OpenBiome 514:Category 444:Salivary 434:Placenta 225:cite web 191:24670166 35:Location 484:Related 327:14 July 304:14 July 278:14 July 182:4648343 99:History 67:Website 439:Uterus 417:Vagina 189:  179:  29:Health 535:Feces 407:Mouth 25:Focus 412:Skin 402:Lung 329:2014 306:2014 280:2014 257:2019 231:link 217:2019 187:PMID 76:.org 397:Gut 177:PMC 169:doi 165:370 72:www 531:: 297:. 248:. 227:}} 223:{{ 208:. 185:. 175:. 163:. 159:. 95:. 44:, 373:e 366:t 359:v 331:. 308:. 282:. 233:) 219:. 193:. 171::

Index

Health
Somerville
Massachusetts
Carolyn Edelstein
www.openbiome.org
Somerville, Massachusetts
human microbiome
hospitals
C. difficile
hospital-acquired infection
fecal microbiota transplantation
gastrointestinal tract
MIT Sloan School of Management
"Multistate point-prevalence survey of health care-associated infections"
doi
10.1056/NEJMoa1306801
PMC
4648343
PMID
24670166
"Onsite with OpenBiome"
cite web
link
"Opinion - Should We Bank Our Own Stool?"
"Student-led Project Banks on Promise of Fecal Transplants"
"A New Kind of Transplant Bank"
"Fecal transplant safety is goal of stool bank"
Official Website
v
t

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