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In 2022, a retrospective study conducted on 82 eyes with OOKP using original
Strampelli technique, showed an anatomical survival of 94% up to 30 years of follow-up. The same study also reported a visual acuity better than 1.00 logMAR (or 20/200 Snellen) at 10 years in 81% of the eyes, and a visual
485:
Iannetti L, Liberali M, Armentano M, Alisi L, Visioli G, Mastromarino D, Edoardo B, Iannetti G (May 2022). "Osteo-odonto-keratoprosthesis according to
Strampelli original technique: A retrospective study with up to 30 years of follow-up".
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is cut from the tooth and a hole is drilled perpendicular to the lamina. The hole is then fitted with a cylindrical lens. The lamina is grown in the patients' cheek for a period of months and then is implanted upon the eye.
214:, Benedetto Strampelli held the chair of ophthalmic surgery at Rome's Ospedale di San Giovanni in Laterano where he was one of the first surgeons in Italy to transplant cornea. In 1953 he was the first Italian to implant
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Falcinelli G, Falsini B, Taloni M, Colliardo P, Falcinelli G (October 2005). "Modified osteo-odonto-keratoprosthesis for treatment of corneal blindness: long-term anatomical and functional outcomes in 181 cases".
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Liu C, Okera S, Tandon R, Herold J, Hull C, Thorp S (September 2008). "Visual rehabilitation in end-stage inflammatory ocular surface disease with the osteo-odonto-keratoprosthesis: results from the UK".
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Another, bigger study comparing OOKP with the lesser known osteo-keratoprosthesis (OKP) in 145 and 82 patients and follow-up terms up to 10 years yielded the following statistics:
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Michael R, Charoenrook V, de la Paz MF, Hitzl W, Temprano J, Barraquer RI (August 2008). "Long-term functional and anatomical results of osteo- and osteoodonto-keratoprosthesis".
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60:, is a medical procedure to restore vision in the most severe cases of corneal and ocular surface patients. It includes removal of a tooth from the patient or a donor.
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At the end of the procedure, light can now enter through the plastic cylinder, and the patient is able to see through this cylinder with good vision.
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The procedure was pioneered by the
Italian ophthalmic surgeon Professor Benedetto Strampelli in the early 1960s. Strampelli was a founder-member of
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There is a significant risk of anatomical failure of lamina in the long term, estimated at 19% in a small study, with the main risks being laminar
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The tooth-bone-cylinder complex is removed from the cheek and inserted into the eye, the mucosal cheek lining is replaced over the implant.
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Viitala R, Franklin V, Green D, Liu C, Lloyd A, Tighe B (January 2009). "Towards a synthetic osteo-odonto-keratoprosthesis".
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The procedure was pioneered by the
Italian ophthalmic surgeon Professor Benedetto Strampelli in Rome in the early 1960s.
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10-year functional survival (visual acuity better than 1.30 logMAR or 20/400 Snellen): 38% for OOKP and 17% for OKP
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2-year functional survival (visual acuity better than 1.30 logMAR or 20/400 Snellen): 63% for OOKP and 49% for OKP
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A bolt-shaped structure is fashioned from the tooth-bone complex which is fitted with a plastic optical cylinder
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The eye is opened up and the entire inner surface of the eyelids, corneal surface and all scar tissue is removed
543:"Strampelli's osteo-odonto-keratoprosthesis. Clinical and histological long-term features of three prostheses"
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Another long-term study of 181 patients puts the chances of retaining an intact OOKP after 18 years at 85%.
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The tooth-bone-cylinder complex is implanted into the patient's cheek to grow a new blood supply
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The cheek mucosal lining over the eye is opened and the inner contents of the eye are removed
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National Dental Centre – 25 May 2005 Tooth-in-eye (OOKP) Surgery Help 8 Regain Sight
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Ricci R, Pecorella I, Ciardi A, Della Rocca C, Di Tondo U, Marchi V (April 1992).
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Inner mucosal lining of the cheek is transplanted onto the new surface of the eye
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Blind man has sight restored by having tooth implanted in his eye
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tooth and part of the adjacent bone and ligaments are removed
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10-year anatomical survival: 66% for OOKP and 47% for OKP
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acuity of 1.21 logMAR (or 20/324 Snellen) at 30 years.
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An operation to graft the OOKP is undertaken in severe
264:"Tooth-in-eye (OOKP) Surgery Help 8 Regain Sight"
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157:of the surgery involves five separate procedures:
603:– story about blind man receiving this procedure
597:– Article about a man receiving this procedure
218:which were manufactured to his own design by
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222:in UK. Strampelli was a founder-member with
228:the International Intra-Ocular Implant Club
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210:The son of the geneticist and agronomist
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407:Graefes Arch. Clin. Exp. Ophthalmol.
283:"Son's tooth helps save dad's sight"
281:Guidera, Anita (28 February 2008).
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632:Surgical procedures and techniques
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266:. www.ndc.com.sg. Archived from
151:OOKP is a two-stage operation:
63:After removal, a longitudinal
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50:Osteo-odonto-keratoprosthesis
22:Osteo-odonto-keratoprosthesis
16:Medical procedure for the eye
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93:Stevens–Johnson syndrome
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58:"tooth in eye" surgery
617:Dentistry procedures
561:10.1136/bjo.76.4.232
308:4 March 2008 at the
226:and Peter Choyce of
212:Nazareno Strampelli
601:Yeshiva World News
245:Refractive surgery
114:, particularly in
452:Arch. Ophthalmol.
287:Irish Independent
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251:References
116:allografts
112:resorption
85:pemphigoid
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147:Procedure
107:failure.
28:Specialty
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306:Archived
234:See also
173:premolar
120:glaucoma
97:trachoma
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186:Stage 2
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341:PMID
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