142:
wind-zone of the building exterior. External pressure and the cascaded negative pressure zones are measured and maintained in real time by electronic sensors, electronically controlled supply and exhaust air handling systems and purpose developed predictive logic controllers in support of management protocols to manage air locks, access and services to prevent loss or ingress of potentially contaminated gases, solids or liquids . Supply air is protected by two 0.001 HEPA filters in tandem, (series mounted) with appropriate pre-filters in purpose designed individual housings. Filters and housings in pairs are then mounted as multiples in parallel according to airflow and volume requirement. This configuration allows the de-contamination, testing and/or replacement of any individual filter without the need to shut down operation. For exhaust air, similar filtration hardware and management arrangements apply. However, at least one stage of exhaust protection of a method not relying on filtration is provided. In the case of AAHL, the system adopted by CSIRO was "air incineration" at 1000 C and a retention/dwell time of more than 4 seconds at that temperature. Liquid scrubbing to prevent escape of formaldehyde is fitted after the afterburner for protection of the environment. Waste liquids can be dosed chemically in steam jacketed stainless steel tanks as the first barrier, followed by heating under pressure and maintained at elevated temperature for an appropriate time. Multiple tanks can be configured in tandem or in parallel according to need.
22:
85:
138:
adoption of one of them by
Australian authorities. The review was carried out by CSIRO AAHL Project Manager Bill Curnow and CSIRO Engineer Arthur Jenkins. They drafted outcomes for each of the levels of security. AAHL was notionally classified as "substantially beyond P4". These were adopted by the Australian Academy of Science and became the basis for Australian Legislation.
145:
AAHL was designed and built before there were any regulations covering bio-containment. The later regulations were written by AAHL personnel. AAHL Staff were at pains to ensure that AAHL could contain any known or yet to be discovered organism. Politically there was opposition to the notion of having
137:
In 1977, Jim
Peacock of the Australian Academy of Science asked Bill Snowdon, then Chief CSIRO AAHL if he could have the newly released USA NIH and the British equivalent requirements for the development of infrastructure for bio-containment reviewed by AAHL personnel with a view to recommending the
141:
The
Australian Centre for Disease Preparedness was commissioned in 1985 as the Australian Animal Health Laboratory, includes a number of laboratories and animal house facilities capable of operating at three steps of negative pressure below the lowest pressure within any part of the extramural
149:
Innovation in the design delivered cost savings of between $ 30M and $ 50M so the design team felt that it was better to err on the safe side than to face the prospect of an angry PM. AAHL was very cost effective and safe as a result. The
Australian Animal Health Laboratory is a Class 4/ P4
102:
184:
300:
305:
146:
the facility at all. The Prime
Minister Malcolm Fraser, although in favor of the project, threatened serious consequences for management if the design team "got it wrong".
315:
340:
325:
310:
335:
320:
261:
202:
169:
188:
124:
106:
217:
95:
42:
67:
In
November 2012 it delivered an experimental vaccine to help protect horses against the deadly
253:
16:
High security laboratory, run by the CSIRO for exotic animal disease diagnosis and research.
153:
The facility was renamed to the
Australian Centre for Disease Preparedness in April 2020.
54:
330:
185:"Vaccine arrives to boost the frontline fight against Hendra virus « News @ CSIRO"
21:
294:
68:
84:
61:
276:
263:
46:
53:
for exotic animal disease diagnosis and research. The lab is one of four
37:), formerly known as the Australian Animal Health Laboratory (AAHL), in
109: in this section. Unsourced material may be challenged and removed.
38:
50:
78:
246:
203:"CSIRO: Geelong - Australian Animal Health Laboratory"
170:"CSIRO: Geelong - Australian Animal Health Laboratory"
60:It opened in 1985 costing $ 185 million, built on
8:
301:Scientific organizations established in 1985
306:Buildings and structures completed in 1985
49:is a high security laboratory, run by the
31:Australian Centre for Disease Preparedness
25:Australian Centre for Disease Preparedness
125:Learn how and when to remove this message
20:
161:
218:"Nation's disease response bolstered"
7:
254:Australian Science at Work Registrar
107:adding citations to reliable sources
316:Buildings and structures in Geelong
14:
183:Andrew Warren (1 November 2012).
341:Veterinary medicine in Australia
326:Research institutes in Australia
311:1985 establishments in Australia
83:
94:needs additional citations for
336:Biosafety level 4 laboratories
321:Veterinary research institutes
1:
357:
57:-4 labs in the country.
26:
24:
103:improve this article
273: /
191:on 2 November 2012.
277:38.151°S 144.389°E
27:
135:
134:
127:
348:
288:
287:
285:
284:
283:
282:-38.151; 144.389
278:
274:
271:
270:
269:
266:
250:
249:
247:Official website
233:
232:
230:
228:
213:
207:
206:
199:
193:
192:
187:. Archived from
180:
174:
173:
166:
130:
123:
119:
116:
110:
87:
79:
356:
355:
351:
350:
349:
347:
346:
345:
291:
290:
281:
279:
275:
272:
267:
264:
262:
260:
259:
245:
244:
241:
236:
226:
224:
215:
214:
210:
201:
200:
196:
182:
181:
177:
168:
167:
163:
159:
131:
120:
114:
111:
100:
88:
77:
55:Biosafety Level
17:
12:
11:
5:
354:
352:
344:
343:
338:
333:
328:
323:
318:
313:
308:
303:
293:
292:
257:
256:
251:
240:
239:External links
237:
235:
234:
208:
194:
175:
160:
158:
155:
133:
132:
91:
89:
82:
76:
73:
15:
13:
10:
9:
6:
4:
3:
2:
353:
342:
339:
337:
334:
332:
329:
327:
324:
322:
319:
317:
314:
312:
309:
307:
304:
302:
299:
298:
296:
289:
286:
255:
252:
248:
243:
242:
238:
223:
219:
212:
209:
204:
198:
195:
190:
186:
179:
176:
171:
165:
162:
156:
154:
151:
147:
143:
139:
129:
126:
118:
108:
104:
98:
97:
92:This section
90:
86:
81:
80:
74:
72:
70:
65:
63:
58:
56:
52:
48:
44:
40:
36:
32:
23:
19:
258:
225:. Retrieved
222:www.csiro.au
221:
211:
197:
189:the original
178:
164:
152:
150:Laboratory.
148:
144:
140:
136:
121:
112:
101:Please help
96:verification
93:
69:Hendra virus
66:
59:
34:
30:
28:
18:
280: /
268:144°23′20″E
295:Categories
265:38°09′04″S
157:References
115:April 2020
62:Corio Oval
47:Australia
43:Victoria
227:4 April
216:CSIRO.
75:History
39:Geelong
331:CSIRO
51:CSIRO
229:2020
35:ACDP
29:The
105:by
297::
220:.
71:.
64:.
45:,
41:,
231:.
205:.
172:.
128:)
122:(
117:)
113:(
99:.
33:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
