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respiratory tract and the digestive tract to other cats. However, studies suggest that a cat cannot transfer the virus to a dog, and vice versa, while sharing a food bowl. Though there is no concrete evidence, there is a potential link between the transfer of the virus between poultry, wild birds, and humans.
19:
exhibit symptoms that can result in death. The viruses cats may get include H5N1 or H7N2, which are subtypes of avian influenza. In order to get the virus, cats need to be in contact with waterfowl, poultry, or uncooked poultry that are infected. Two of the main organs that the virus affects are the
163:
Researchers have given tigers an antiviral treatment of
Oseltamivir with a dose of 75 mg/60 kg two times a day. The specific dosage was extrapolated from human data, but there hasn't been any data to suggest protection. As with many antiviral treatments, the dosage depends on the species.
54:
H5N1 was first discovered in domestic and wild cats in Asia, specifically in 2003 in the Thai zoo where two tigers and two leopards died. In 2004, the Thai zoo had 147 tigers that died or were euthanized. This was then followed by an outbreak in
Germany in 2006, where three stray cats were found to
159:
If a cat is exhibiting symptoms, they should be put into isolation and kept indoors. Then they should be taken to a vet to get tested for the presence of H5N1. If there is a possibility that the cat has Avian
Influenza, then there should be extra care when handling the cat. Some of the precautions
100:
as the H5N1 virus, and therefore worked on preventing death from two different strains of the virus, HPAIV A/Vietnam/1194/2004 and HPAIV A/Indonesia/05/2005. However, some of the cats that were vaccinated did exhibit hyperthermia and weight loss, and all of the cats did have some disease change
66:
The most common way a cat can obtain H5N1 is by consuming an infected bird. This has been studied in the 2006 and 2007 cases in
Germany and Austria where the strains between the cat and the infected birds were not different between the species. A cat is able to then transfer the virus via the
85:
One epidemiological study that was performed in
Germany and Austria on 171 cats found that less than 1.8% of this population had H5N1. In this same sample population of cats, less than 2.6% had antibodies to H5N1. Even though Germany and Austria are among the countries that have had naturally
692:
Stittelaar, Koert J.; Lacombe, Valérie; van
Lavieren, Rob; van Amerongen, Geert; Simon, James; Cozette, Valérie; Swayne, David E.; Poulet, Hervé; Osterhaus, Albert D.M.E. (1 July 2010). "Cross-clade immunity in cats vaccinated with a canarypox-vectored avian influenza vaccine".
125:. In a case in February 2004, a 2-year-old male cat was panting and convulsing on top of having a fever two days prior to death. This cat also had lesions that were identified as renal congestion, pulmonary congestion,
93:, specifically CD4 and CD8, in the cat after viral infection. Though the mechanism is not fully known, there seems to be an inverse relationship with the amount of T cells present and the amount of infected cells.
34:
The H5N1 virus has been found in China, Thailand, Vietnam, Indonesia, Iraq, Austria, Germany, and Poland. Besides being found in domestic cats, the virus has infected a variety of wild cats such as the
211:
Thiry, Etienne; Addie, Diane; Belák, Sándor; Boucraut-Baralon, Corine; Egberink, Herman; Frymus, Tadeusz; Gruffydd-Jones, Tim; Hartmann, Katrin; Hosie, Margaret J.; Lloret, Albert (1 July 2009).
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include avoiding all direct contact with the cat by wearing gloves, masks, and goggles. Whatever surfaces the cat comes in contact with should be disinfected with standard household cleaners.
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be either dying or dead during the peak time of the virus outbreak. Currently, as of June 2023, there is an ongoing outbreak in Poland with at least 9 confirmed cases and multiple deaths.
148:
However, a cat that is infected with a low dose of the virus may not necessarily show symptoms. Though they may be asymptomatic, they can still transfer small amounts of the virus.
665:
Giese, Matthias; Harder, Timm C.; Teifke, Jens P.; Mettenleiter, Thomas C.; Vahlenkamp, Thomas W. (1 March 2009). "The role of T cells in avian influenza H5N1 infected cats".
156:
Cats can be protected from H5N1 if they are given a vaccination, as mentioned above. However, it was also found that cats can still shed some of the virus but in low numbers.
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Starick, E.; Beer, M.; Hoffmann, B.; Staubach, C.; Werner, O.; Globig, A.; Strebelow, G.; Grund, C.; Durban, M.; Conraths, F.J.; Mettenleiter, T.; Harder, T. (1 April 2008).
373:
Philippa J, Baas C, Beyer W, et al. (May 2007). "Vaccination against highly pathogenic avian influenza H5N1 virus in zoos using an adjuvanted inactivated H5N2 vaccine".
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Once the cat is infected, after an incubation period of 2 to 3 days, the virus can be found in the respiratory tissues, attached to the type II pneumocytes and alveolar
448:"Phylogenetic analyses of highly pathogenic avian influenza virus isolates from Germany in 2006 and 2007 suggest at least three separate introductions of H5N1 virus"
96:
Another study to test whether the ALVAC recombinant canarypox virus could prime the immune system in cats was performed. This vaccine has the same
74:, as well as the intestinal tissues. There have also been some cases where the virus has been found in the brain and other systems in the body.
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447:
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Because the virus infects the lungs of cats, it is one of the preferred model animals to study the effects of H5N1 in humans.
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As of right now the H5N1 virus has not adapted to transfer in between mammals, but there is a fear that this can occur.
608:"Prevalence of influenza A H5N1 virus in cats from areas with occurrence of highly pathogenic avian influenza in birds"
606:
Marschall, J; Schulz, B; Harderprivdoz, T; Vahlenkampprivdoz, T; Huebner, J; Huisinga, E; Hartmann, K (1 August 2008).
101:(assuming lesions) in their lungs. All of the cats, except one, still excreted the virus even after being vaccinated.
183:"Outbreak of Influenza A(H7N2) Among Cats in an Animal Shelter With Cat-to-Human Transmission—New York City, 2016"
97:
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121:. There have even been recorded cases where a cat has neurological symptoms such as circling or
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Cardona CJ, Xing Z, Sandrock CE, Davis CE (July 2009). "Avian influenza in birds and mammals".
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Yee KS, Carpenter TE, Cardona CJ (July 2009). "Epidemiology of H5N1 avian influenza".
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Harder TC, Vahlenkamp TW (March 2010). "Influenza virus infections in dogs and cats".
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occurring cases, this study shows that very few cats have contracted the disease.
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490:"Polish officials probe H5N1 avian flu link to cat deaths"
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133:. Upon inspection, the cat also had cerebral congestion,
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559:"H5N1 pathogenesis studies in mammalian models"
515:Kalthoff D, Globig A, Beer M (January 2010).
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89:There have also been studies looking at the
265:"Avian influenza A H5N1 infections in cats"
263:Marschall, J; Hartmann, K (1 August 2008).
30:Global spread of H5N1 § Felidae (cats)
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612:Journal of Feline Medicine & Surgery
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557:Belser JA, Tumpey TM (February 2013).
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181:Lee, Christopher T (28 July 2017).
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496:. University of Minnesota
143:serosae of the intestines
17:Cats with avian influenza
152:Treatment and prevention
455:Veterinary Microbiology
81:Studies done with cats
488:Schnirring, Lisa.
37:Asiatic golden cat
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168:References
28:See also:
563:Virus Res
131:pneumonia
764:Category
750:18485480
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644:18640861
635:10832910
593:23458998
541:19782482
475:18031958
430:18448168
395:17403559
353:19896216
307:29347001
299:18619884
290:10832898
247:19481042
115:lethargy
105:Symptoms
49:leopards
695:Vaccine
652:6326717
584:5858902
500:28 June
375:Vaccine
238:7128855
141:in the
119:dyspnea
91:T cells
24:History
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648:S2CID
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303:S2CID
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111:fever
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