Knowledge (XXG)

ALCAT test

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39:"These findings reject the null hypothesis and show that a diet guided by leucocyte activation testing results in demonstrable clinical improvement in IBS. These clinical results, associated with a reduction in plasma neutrophil elastase, have implications for better understanding the role of food intolerance and the pathophysiology of IBS." 74:"These results have been shown to not be reproducible, give different results when duplicate samples are analysed blindly, don't correlate with those from conventional testing, and 'diagnose' food hypersensitivity in subjects with conditions where food allergy is not considered to play a pathogenic role." 24:) is one that claims to measure adverse reactions to dietary substances. It was created by American Medical Testing Laboratories and is now marketed by Cell Science Systems (also known as ALCAT Diagnostic Systems) of 332: 63: 389: 58:
Research published up to 2010 did not support the test or provide evidence that it was a reliable medical diagnostic tool; since it had not been
340: 48: 59: 237:"Non-conventional approaches to allergy testing: reconciling patient autonomy with medical practitioners' concerns" 43:
A study conducted in 2014 demonstrated reactions identified as "severe" were associated with the up-regulation of
33: 25: 144:"Food reactivity on the ALCAT leukocyte activation test is associated with upregulation of CD11b on T cells" 29: 96:"Efficacy of individualised diets in patients with irritable bowel syndrome: a randomised controlled trial" 384: 236: 368: 264: 67: 339:. Australasian Society of Clinical Immunology and Allergy (ASCIA). November 2007. Archived from 333:"Unorthodox Techniques for the Diagnosis and Treatment of allergy, Asthma and Immune Disorders" 314: 287: 256: 217: 183: 125: 248: 115: 107: 52: 44: 252: 120: 95: 32:
published in BMJ Open Gastroenterology in 2017 demonstrated improvement for those with
378: 143: 268: 94:
Ali A, Weiss TR, McKee D, Scherban A, Khan S, Fields MR, et al. (2017-09-01).
168: 111: 318: 291: 260: 221: 187: 129: 202: 55:, suggesting a basis for further research into the mechanisms alleged. 176:
Journal of Investigational Allergology & Clinical Immunology
66:
classified the ALCAT with other forms of cytotoxic tests as
363: 284:
Rinsho Byori. The Japanese Journal of Clinical Pathology
64:
Australasian Society of Clinical Immunology and Allergy
201:Gerez IF, Shek LP, Chng HH, Lee BW (January 2010). 235:Mullins RJ, Heddle RJ, Smith P (August 2005). 8: 282:Yasuhara A, Yamazaki D (October 2003). "". 169:"Unproven techniques in allergy diagnosis" 89: 87: 119: 83: 390:Alternative medical diagnostic methods 7: 203:"Diagnostic tests for food allergy" 253:10.5694/j.1326-5377.2005.tb06986.x 14: 241:The Medical Journal of Australia 62:. In a position statement, the 18:antigen leukocyte antibody test 1: 369:Food allergy vs. intolerance 305:Ito K (November 2008). "". 112:10.1136/bmjgast-2017-000164 406: 28:. Researched conducted at 210:Singapore Medical Journal 100:BMJ Open Gastroenterology 337:ASCIA Position Statement 34:irritable bowel syndrome 26:Deerfield Beach, Florida 30:Yale School of Medicine 364:ALCAT official website 76: 41: 72: 37: 286:. Suppl 127: 73–8. 167:Wüthrich B (2005). 68:inappropriate tests 397: 352: 351: 349: 348: 329: 323: 322: 302: 296: 295: 279: 273: 272: 232: 226: 225: 207: 198: 192: 191: 173: 164: 158: 157: 155: 154: 140: 134: 133: 123: 91: 70:, saying of them 405: 404: 400: 399: 398: 396: 395: 394: 375: 374: 360: 355: 346: 344: 331: 330: 326: 313:(11): 1109–16. 304: 303: 299: 281: 280: 276: 234: 233: 229: 205: 200: 199: 195: 171: 166: 165: 161: 152: 150: 142: 141: 137: 93: 92: 85: 81: 12: 11: 5: 403: 401: 393: 392: 387: 377: 376: 373: 372: 366: 359: 358:External links 356: 354: 353: 324: 297: 274: 227: 193: 159: 135: 106:(1): e000164. 82: 80: 77: 13: 10: 9: 6: 4: 3: 2: 402: 391: 388: 386: 383: 382: 380: 370: 367: 365: 362: 361: 357: 343:on 2012-09-08 342: 338: 334: 328: 325: 320: 316: 312: 308: 301: 298: 293: 289: 285: 278: 275: 270: 266: 262: 258: 254: 250: 246: 242: 238: 231: 228: 223: 219: 215: 211: 204: 197: 194: 189: 185: 181: 177: 170: 163: 160: 149: 145: 139: 136: 131: 127: 122: 117: 113: 109: 105: 101: 97: 90: 88: 84: 78: 75: 71: 69: 65: 61: 56: 54: 50: 46: 40: 36: 35: 31: 27: 23: 19: 345:. Retrieved 341:the original 336: 327: 310: 306: 300: 283: 277: 247:(4): 173–4. 244: 240: 230: 213: 209: 196: 182:(2): 86–90. 179: 175: 162: 151:. Retrieved 148:ResearchGate 147: 138: 103: 99: 73: 57: 53:CD8+ T cells 42: 38: 21: 17: 15: 385:Allergology 379:Categories 347:2012-10-09 216:(1): 4–9. 153:2017-11-22 79:References 22:ALCAT test 60:validated 319:19052505 292:14653218 269:30242205 261:16097911 222:20200768 188:16047707 130:29018540 371:(WebMD) 307:Arerugi 121:5628288 317:  290:  267:  259:  220:  186:  128:  118:  51:+ and 265:S2CID 206:(PDF) 172:(PDF) 45:CD11b 315:PMID 288:PMID 257:PMID 218:PMID 184:PMID 126:PMID 16:The 249:doi 245:183 116:PMC 108:doi 49:CD4 47:on 381:: 335:. 311:57 309:. 263:. 255:. 243:. 239:. 214:51 212:. 208:. 180:15 178:. 174:. 146:. 124:. 114:. 102:. 98:. 86:^ 350:. 321:. 294:. 271:. 251:: 224:. 190:. 156:. 132:. 110:: 104:4 20:(

Index

Deerfield Beach, Florida
Yale School of Medicine
irritable bowel syndrome
CD11b
CD4
CD8+ T cells
validated
Australasian Society of Clinical Immunology and Allergy
inappropriate tests


"Efficacy of individualised diets in patients with irritable bowel syndrome: a randomised controlled trial"
doi
10.1136/bmjgast-2017-000164
PMC
5628288
PMID
29018540
"Food reactivity on the ALCAT leukocyte activation test is associated with upregulation of CD11b on T cells"
"Unproven techniques in allergy diagnosis"
PMID
16047707
"Diagnostic tests for food allergy"
PMID
20200768
"Non-conventional approaches to allergy testing: reconciling patient autonomy with medical practitioners' concerns"
doi
10.5694/j.1326-5377.2005.tb06986.x
PMID
16097911

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