32:
190:
582:
Knaus WA, Wagner DP, Draper EA, Zimmerman JE, Bergner M, Bastos PG, Sirio CA, Murphy DJ, Lotring T, Damiano A, et al. (1991). "The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults".
408:
In the original research paper that described the APACHE II score, patient prognosis (specifically, predicted mortality) was computed based on the patient's APACHE II score in combination with the principal diagnosis at admission.
218:
by editing this article to remove any non-free copyrighted content and attributing free content correctly, or flagging the content for deletion. Please be sure that the supposed source of the copyright violation is not itself a
386:
class IV heart failure, severe respiratory disease, dialysis dependent) or is immunocompromised (i.e. due to chemotherapy, radiation, high dose steroid therapy, or advanced leukemia, lymphoma or AIDS) assign points as follows:
151:(ICU): an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death. The first APACHE model was presented by Knaus et al. in 1981.
627:
Zimmerman JE, Kramer AA, McNair DS, Malila FM, et al. (2006). "Acute
Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today's critically ill patients".
405:
The score is not recalculated during the stay. It is by definition an admission score. If a patient is discharged from the ICU and subsequently readmitted, a new APACHE II score is calculated.
468:
APACHE IV, published in 2006, is the latest version. The model was developed using data from 104 intensive care units (ICUs) in 45 U.S. hospitals and could be recommended to use in U.S. ICUs.
1320:
951:
446:, major organ involved, and distinction between surgical/medical categories); age, sex, race and preexisting comorbidities; and location prior to ICU admission (operating room, recovery or
159:
APACHE II was designed to measure the severity of disease for adult patients admitted to intensive care units. It has not been validated for use in children or young people aged under 16.
176:
Even though newer scoring systems, such as APACHE III, have replaced APACHE II in many places, APACHE II continues to be used extensively because so much documentation is based on it.
383:
536:
Knaus WA, Zimmerman JE, Wagner DP, Draper EA, Lawrence DE (1981). "APACHE-acute physiology and chronic health evaluation: a physiologically based classification system".
711:
442:
Adds additional variables to the APACHE III Score including the primary reason for ICU admission (from a reference list of 212 conditions classified according to
200:
1394:
989:
240:
The point score is calculated from 12 admission physiologic variables comprising the Acute
Physiology Score, the patient's age, and chronic health status:
215:
477:
817:
704:
53:
912:
897:
837:
1310:
1007:
75:
420:
The score was validated on the dataset from 17,440 adult medical/surgical intensive care unit (ICU) admissions at 40 US hospitals.
697:
1153:
1012:
945:
249:
1284:
220:
791:
774:
768:
1194:
1128:
46:
40:
786:
731:
457:
To evaluate the severity of disease 20 physiologic variables are measured, compared to 12 variables for APACHE II.
169:
APACHE II score can be used to describe the morbidity of a patient when comparing the outcome with other patients.
1315:
1111:
1106:
1057:
57:
500:
Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985). "APACHE II: a severity of disease classification system".
106:
382:
If the patient has a history of severe organ system insufficiency (i.e. liver cirrhosis, portal hypertension,
1399:
1209:
1052:
1037:
720:
20:
1289:
454:
When possible, the time between the patient's arrival at the hospital and their ICU admission is recorded.
208:
1091:
308:
269:
1294:
1215:
125:
1146:
966:
447:
685:
Commonly used website to calculate APACHE II score with visual representation of predicted mortality
172:
Predicted mortalities are averaged for groups of patients in order to specify the group's morbidity.
1189:
1096:
907:
902:
892:
845:
762:
746:
148:
141:
1238:
1069:
1002:
919:
880:
855:
780:
652:
608:
561:
313:
432:
Provides an initial risk classification of severely ill hospitalized patients in defined groups.
1341:
1087:
887:
865:
850:
741:
644:
600:
553:
517:
1199:
870:
636:
592:
545:
509:
284:
263:
189:
1225:
1123:
997:
402:
values and limiting the number of options so that data fits on a single-sheet paper form.
144:
166:
Some procedures or some medicine is only given to patients with a certain APACHE II score
1336:
1179:
956:
640:
1388:
1064:
1047:
549:
513:
656:
565:
1373:
1274:
1141:
1133:
1079:
1017:
981:
971:
875:
832:
612:
289:
684:
112:
1356:
1279:
860:
417:
A method to compute a refined score known as APACHE III was published in 1991.
1363:
1346:
1258:
1174:
1118:
924:
674:
303:
297:
279:
596:
1351:
1169:
648:
689:
679:
604:
557:
521:
1253:
1204:
1184:
1042:
961:
736:
526:(This is the first published description of the APACHE II scoring system)
443:
274:
99:
1368:
1248:
399:
827:
822:
675:
APACHE II calculator script in Python 3.4. (licensed under GPL 3.0)
140:") is a severity-of-disease classification system, one of several
120:
391:
a. for nonoperative or emergency postoperative patients: 5 points
244:
A. Acute
Physiology Score (measured within 24 hours of admission)
1243:
929:
257:
253:
147:. It is applied within 24 hours of admission of a patient to an
693:
183:
25:
1321:
European
Society of Paediatric and Neonatal Intensive Care
398:
The method is optimized for manual calculation, by using
450:, transfer or readmission from another hospital or ICU).
162:
This scoring system is used in many ways which include:
952:
Critical illness–related corticosteroid insufficiency
680:
Microsoft Excel function to calculate APACHE II score
423:
The prognostic system of APACHE III has two options:
1329:
1303:
1267:
1224:
1162:
1078:
1030:
980:
938:
807:
800:
755:
119:
105:
95:
90:
138:Acute Physiology and Chronic Health Evaluation II
394:b. for elective postoperative patients: 2 points
16:Classification of disease severity used in ICUs
705:
577:
575:
495:
493:
19:"APACHE" redirects here. For other uses, see
8:
300:(Double point score for acute renal failure)
804:
712:
698:
690:
478:ASA physical status classification system
76:Learn how and when to remove this message
324:
39:This article includes a list of general
489:
460:APACHE III scores range from 0 to 299.
87:
7:
1200:Recombinant activated protein C
913:Multiple organ dysfunction syndrome
898:Acute respiratory distress syndrome
838:Multiple organ dysfunction syndrome
1395:Diagnostic intensive care medicine
641:10.1097/01.CCM.0000215112.84523.F0
209:Knowledge (XXG)'s copyright policy
45:it lacks sufficient corresponding
14:
1311:Society of Critical Care Medicine
1008:Ventilator-associated lung injury
550:10.1097/00003246-198108000-00008
514:10.1097/00003246-198510000-00009
188:
30:
1013:Ventilator-associated pneumonia
946:Critical illness polyneuropathy
437:APACHE III predictive equation
260:≥0.5 or <0.5, respectively)
1:
792:Geriatric intensive-care unit
775:Pediatric intensive care unit
214:Please review the source and
1195:Neuromuscular-blocking drugs
1138:Nutritional supplementation
769:Neonatal intensive care unit
1295:Water-electrolyte imbalance
1129:Early goal-directed therapy
1416:
1147:Total parenteral nutrition
1080:Life-supporting treatments
787:Critical illness insurance
18:
1316:Surviving Sepsis Campaign
1112:Ventricular assist device
1107:Intra-aortic balloon pump
1058:Pulmonary artery catheter
727:
597:10.1378/chest.100.6.1619
378:C. Chronic health points
197:This article or section
1210:Stress ulcer prevention
1154:Therapeutic hypothermia
1053:Central venous catheter
721:Intensive care medicine
203:from another location,
60:more precise citations.
21:Apache (disambiguation)
1285:Level of consciousness
1092:mechanical ventilation
990:Methicillin-resistant
629:Critical Care Medicine
538:Critical Care Medicine
502:Critical Care Medicine
309:white blood cell count
270:mean arterial pressure
221:Knowledge (XXG) mirror
992:Staphylococcus aureus
316:(15 minus actual GCS)
967:Stress hyperglycemia
808:Organ system failure
742:Medical specialities
448:emergency department
1330:Related specialties
1290:Acid–base imbalance
1226:ICU scoring systems
1097:Tracheal intubation
908:Respiratory failure
903:Acute liver failure
893:Acute renal failure
763:Intensive care unit
747:Respiratory therapy
149:intensive care unit
1239:Glasgow Coma Scale
1190:Intravenous fluids
1070:Screening cultures
1038:Arterial blood gas
1003:Refeeding syndrome
920:Neonatal infection
881:Vasodilatory shock
856:Distributive shock
781:Coronary care unit
314:Glasgow Coma Scale
1382:
1381:
1342:Internal medicine
1088:Airway management
1026:
1025:
866:Obstructive shock
851:Cardiogenic shock
375:
374:
238:
237:
201:copied and pasted
131:
130:
86:
85:
78:
1407:
1103:Cardiac devices
957:Decubitus ulcers
871:Neurogenic shock
805:
714:
707:
700:
691:
662:
660:
624:
618:
616:
579:
570:
569:
533:
527:
525:
497:
427:APACHE III Score
325:
285:respiratory rate
264:body temperature
233:
230:
224:
207:in violation of
192:
184:
115:
88:
81:
74:
70:
67:
61:
56:this article by
47:inline citations
34:
33:
26:
1415:
1414:
1410:
1409:
1408:
1406:
1405:
1404:
1385:
1384:
1383:
1378:
1325:
1299:
1263:
1220:
1180:Antithrombotics
1158:
1142:Enteral feeding
1124:Kidney dialysis
1074:
1022:
998:Oxygen toxicity
976:
934:
796:
751:
723:
718:
671:
666:
665:
635:(5): 1297–310.
626:
625:
621:
581:
580:
573:
535:
534:
530:
499:
498:
491:
486:
474:
466:
415:
294:serum potassium
234:
228:
225:
213:
193:
182:
157:
145:scoring systems
111:
82:
71:
65:
62:
52:Please help to
51:
35:
31:
24:
17:
12:
11:
5:
1413:
1411:
1403:
1402:
1400:Medical scales
1397:
1387:
1386:
1380:
1379:
1377:
1376:
1371:
1366:
1361:
1360:
1359:
1354:
1349:
1339:
1337:Anesthesiology
1333:
1331:
1327:
1326:
1324:
1323:
1318:
1313:
1307:
1305:
1301:
1300:
1298:
1297:
1292:
1287:
1282:
1277:
1271:
1269:
1265:
1264:
1262:
1261:
1256:
1251:
1246:
1241:
1236:
1234:APACHE II
1230:
1228:
1222:
1221:
1219:
1218:
1213:
1207:
1202:
1197:
1192:
1187:
1182:
1177:
1172:
1166:
1164:
1160:
1159:
1157:
1156:
1151:
1150:
1149:
1144:
1136:
1131:
1126:
1121:
1116:
1115:
1114:
1109:
1101:
1100:
1099:
1084:
1082:
1076:
1075:
1073:
1072:
1067:
1065:Blood cultures
1062:
1061:
1060:
1055:
1050:
1040:
1034:
1032:
1028:
1027:
1024:
1023:
1021:
1020:
1015:
1010:
1005:
1000:
995:
986:
984:
978:
977:
975:
974:
969:
964:
959:
954:
949:
942:
940:
936:
935:
933:
932:
927:
922:
916:
915:
910:
905:
900:
895:
890:
884:
883:
878:
873:
868:
863:
858:
853:
848:
841:
840:
835:
830:
825:
820:
815:
814:Shock sequence
811:
809:
802:
798:
797:
795:
794:
789:
784:
778:
772:
766:
759:
757:
753:
752:
750:
749:
744:
739:
734:
732:Health science
728:
725:
724:
719:
717:
716:
709:
702:
694:
688:
687:
682:
677:
670:
669:External links
667:
664:
663:
619:
591:(6): 1619–36.
571:
528:
508:(10): 818–29.
488:
487:
485:
482:
481:
480:
473:
470:
465:
462:
452:
451:
439:
438:
434:
433:
429:
428:
414:
411:
396:
395:
392:
380:
379:
373:
372:
369:
365:
364:
361:
357:
356:
353:
349:
348:
345:
341:
340:
337:
333:
332:
329:
323:
322:
318:
317:
311:
306:
301:
295:
292:
287:
282:
277:
272:
267:
261:
246:
245:
236:
235:
199:may have been
196:
194:
187:
181:
178:
174:
173:
170:
167:
156:
153:
129:
128:
123:
117:
116:
109:
103:
102:
97:
93:
92:
84:
83:
38:
36:
29:
15:
13:
10:
9:
6:
4:
3:
2:
1412:
1401:
1398:
1396:
1393:
1392:
1390:
1375:
1372:
1370:
1367:
1365:
1362:
1358:
1355:
1353:
1350:
1348:
1345:
1344:
1343:
1340:
1338:
1335:
1334:
1332:
1328:
1322:
1319:
1317:
1314:
1312:
1309:
1308:
1306:
1304:Organisations
1302:
1296:
1293:
1291:
1288:
1286:
1283:
1281:
1278:
1276:
1273:
1272:
1270:
1266:
1260:
1257:
1255:
1254:SAPS III
1252:
1250:
1247:
1245:
1242:
1240:
1237:
1235:
1232:
1231:
1229:
1227:
1223:
1217:
1214:
1211:
1208:
1206:
1203:
1201:
1198:
1196:
1193:
1191:
1188:
1186:
1183:
1181:
1178:
1176:
1173:
1171:
1168:
1167:
1165:
1161:
1155:
1152:
1148:
1145:
1143:
1140:
1139:
1137:
1135:
1132:
1130:
1127:
1125:
1122:
1120:
1117:
1113:
1110:
1108:
1105:
1104:
1102:
1098:
1095:
1094:
1093:
1089:
1086:
1085:
1083:
1081:
1077:
1071:
1068:
1066:
1063:
1059:
1056:
1054:
1051:
1049:
1048:Arterial line
1046:
1045:
1044:
1041:
1039:
1036:
1035:
1033:
1029:
1019:
1016:
1014:
1011:
1009:
1006:
1004:
1001:
999:
996:
994:
993:
988:
987:
985:
983:
979:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
947:
944:
943:
941:
939:Complications
937:
931:
928:
926:
923:
921:
918:
917:
914:
911:
909:
906:
904:
901:
899:
896:
894:
891:
889:
888:Organ failure
886:
885:
882:
879:
877:
874:
872:
869:
867:
864:
862:
859:
857:
854:
852:
849:
847:
843:
842:
839:
836:
834:
831:
829:
828:Severe sepsis
826:
824:
821:
819:
816:
813:
812:
810:
806:
803:
799:
793:
790:
788:
785:
782:
779:
776:
773:
770:
767:
764:
761:
760:
758:
756:General terms
754:
748:
745:
743:
740:
738:
735:
733:
730:
729:
726:
722:
715:
710:
708:
703:
701:
696:
695:
692:
686:
683:
681:
678:
676:
673:
672:
668:
658:
654:
650:
646:
642:
638:
634:
630:
623:
620:
614:
610:
606:
602:
598:
594:
590:
586:
578:
576:
572:
567:
563:
559:
555:
551:
547:
543:
539:
532:
529:
523:
519:
515:
511:
507:
503:
496:
494:
490:
483:
479:
476:
475:
471:
469:
463:
461:
458:
455:
449:
445:
441:
440:
436:
435:
431:
430:
426:
425:
424:
421:
418:
412:
410:
406:
403:
401:
393:
390:
389:
388:
385:
377:
376:
370:
367:
366:
362:
359:
358:
354:
351:
350:
346:
343:
342:
338:
335:
334:
330:
327:
326:
321:B. Age points
320:
319:
315:
312:
310:
307:
305:
302:
299:
296:
293:
291:
288:
286:
283:
281:
278:
276:
273:
271:
268:
265:
262:
259:
255:
251:
248:
247:
243:
242:
241:
232:
229:December 2022
222:
217:
211:
210:
206:
202:
195:
191:
186:
185:
179:
177:
171:
168:
165:
164:
163:
160:
154:
152:
150:
146:
143:
139:
135:
127:
124:
122:
118:
114:
110:
108:
104:
101:
98:
94:
89:
80:
77:
69:
59:
55:
49:
48:
42:
37:
28:
27:
22:
1374:Traumatology
1275:Hemodynamics
1249:SAPS II
1233:
1216:Vasopressors
1134:Induced coma
991:
982:Iatrogenesis
972:Stress ulcer
876:Spinal shock
833:Septic shock
632:
628:
622:
588:
584:
544:(8): 591–7.
541:
537:
531:
505:
501:
467:
459:
456:
453:
422:
419:
416:
407:
404:
397:
381:
290:serum sodium
239:
226:
204:
198:
175:
161:
158:
137:
133:
132:
72:
66:October 2010
63:
44:
1357:Pulmonology
1280:Hypotension
1175:Antibiotics
1018:Dialytrauma
861:Anaphylaxis
216:remedy this
180:Calculation
155:Application
58:introducing
1389:Categories
1364:Pediatrics
1347:Cardiology
1268:Physiology
1170:Analgesics
1119:Chest tube
948:/ myopathy
925:Polytrauma
801:Conditions
484:References
413:APACHE III
304:hematocrit
298:creatinine
280:heart rate
96:Calculator
41:references
1352:Neurology
1205:Sedatives
1185:Inotropes
1031:Diagnosis
464:APACHE IV
328:AGE (yrs)
134:APACHE II
91:APACHE II
1043:Catheter
962:Fungemia
737:Medicine
657:34985998
649:16540951
566:44301003
472:See also
444:etiology
275:blood pH
266:(rectal)
205:possibly
1369:Surgery
613:1848227
605:1959406
558:7261642
522:3928249
400:integer
331:Points
113:D018806
54:improve
844:Other
823:Sepsis
777:(PICU)
771:(NICU)
655:
647:
611:
603:
564:
556:
520:
126:9264-3
100:MDCalc
43:, but
1212:drugs
1163:Drugs
846:shock
783:(CCU)
765:(ICU)
653:S2CID
609:S2CID
585:Chest
562:S2CID
360:65-74
352:55-64
344:45-54
256:(for
250:AaDO2
121:LOINC
1259:SOFA
1244:PIM2
1090:and
930:Coma
818:SIRS
645:PMID
601:PMID
554:PMID
518:PMID
384:NYHA
258:FiO2
254:PaO2
107:MeSH
637:doi
593:doi
589:100
546:doi
510:doi
368:≥75
336:≤44
252:or
142:ICU
1391::
651:.
643:.
633:34
631:.
607:.
599:.
587:.
574:^
560:.
552:.
540:.
516:.
506:13
504:.
492:^
371:6
363:5
355:3
347:2
339:0
136:("
713:e
706:t
699:v
661:.
659:.
639::
617:.
615:.
595::
568:.
548::
542:9
524:.
512::
231:)
227:(
223:.
212:.
79:)
73:(
68:)
64:(
50:.
23:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
