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Fraction of inspired oxygen

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966: 569:, is a comparison between the oxygen level in the blood and the oxygen concentration that is breathed. This helps to determine the degree of any problems with how the lungs transfer oxygen to the blood. A sample of arterial blood is collected for this test. With a normal P 304: 759: 149: 1087:
Allardet-Servent J, Forel JM, Roch A, Guervilly C, Chiche L, Castanier M, et al. (2009). "FIO2 and acute respiratory distress syndrome definition during lung protective ventilation".
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in the inhaled gas. Medical patients experiencing difficulty breathing are provided with oxygen-enriched air, which means a higher-than-atmospheric
961:{\displaystyle P_{A}{\ce {O2}}=F_{I}{\ce {O2}}(PB-P{\ce {H2O}})-P_{A}{\ce {CO2}}\left(F_{I}{\ce {O2}}+{\frac {1-F_{I}{\ce {O2}}}{R}}\right)} 635: 631: 627: 1242: 451: 1213: 299:{\displaystyle P_{A}{\ce {O2}}={\frac {P_{E}{\ce {O2}}-P_{I}{\ce {O2}}{\frac {V_{D}}{V_{t}}}}{1-{\frac {V_{D}}{V_{t}}}}}} 661: 120:
is used to represent the percentage of oxygen participating in gas-exchange. If the barometric pressure changes, the
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Tietz NW (Ed): Clinical Guide to Laboratory Tests, 3rd ed. W. B. Saunders, Philadelphia, PA, 1995.
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is found to be 100 mmHg. Since the patient is receiving oxygen-saturated air resulting in a
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are the partial pressures of oxygen in alveolar, expired, and inspired gas, respectively, and
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risk score for intensive respiratory or vasopressor support in community-acquired pneumonia.
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Mason, R. Murray and Nadel's Textbook of Respiratory Medicine, 5th ed. Philadelphia, PA 2010
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Toy P, Popovsky MA, Abraham E, Ambruso DR, Holness LG, Kopko PM, et al. (2005).
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is the following formula, used to calculate the partial pressure of alveolar gas:
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ratio less than or equal to 250 mmHg is one of the minor criteria for severe
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is typically maintained below 0.5 even with mechanical ventilation, to avoid
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ratio less than or equal to 200 mmHg is necessary for the diagnosis of
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ratio less than or equal to 333 mmHg is one of the variables in the
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Volumetric proportion of oxygen to other constituents in a breathing gas
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value should be used in the APACHE II score calculation. Otherwise, the
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American Journal of Physiology. Lung Cellular and Molecular Physiology
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is the assumed percentage of oxygen concentration participating in
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After drawing an arterial blood gas sample from a patient the P
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ratio would be 100 mmHg/0.50 = 200 mmHg.
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is the ratio of physiologic dead space over tidal volume.
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of oxygen changes with the change in barometric pressure.
65:. Natural air includes 21% oxygen, which is equivalent to 943: 906: 876: 842: 812: 784: 233: 205: 174: 762: 664:(i.e., possible indication for inpatient treatment). 152: 577:of 60–100 mmHg and an oxygen content of 1120: 1118: 960: 496:per the American-European Consensus Conference on 298: 634:. The more recent Berlin criteria defines mild 607:ratio ranges between 300 and 500 mmHg. A P 87:than 0.21; up to 1.00 which means 100% oxygen. 1082: 1080: 561:and fraction of inspired oxygen, known as the 8: 1035:"Bench-to-bedside review: oxygen as a drug" 76:of 0.21. Oxygen-enriched air has a higher 1060: 1050: 1001: 942: 937: 932: 926: 913: 905: 900: 895: 889: 875: 870: 865: 859: 841: 836: 831: 811: 806: 801: 795: 783: 778: 773: 767: 761: 450:values equal to or greater than 0.5, the 285: 275: 269: 253: 243: 237: 232: 227: 222: 216: 204: 199: 194: 188: 181: 173: 168: 163: 157: 151: 50:, is the molar or volumetric fraction of 976: 638:at a ratio of less than 300 mmHg. 511:has been shown to alter the ratio of P 7: 46:), correctly denoted with a capital 628:acute respiratory distress syndrome 1169:10.1097/01.ccm.0000159849.94750.51 25: 1224:by common oxygen deliver systems. 144:Abbreviated alveolar air equation 559:partial pressure arterial oxygen 984:Wagner, Peter D. (2021-03-01). 588:of 0.21 of room air, a normal P 849: 816: 716:of 50% oxygen his calculated P 131:may remain constant while the 1: 1101:10.1097/CCM.0b013e31819261db 662:community acquired pneumonia 492:is used as an indicator of 31:Fraction of inspired oxygen 1259: 1003:10.1152/ajplung.00610.2020 452:alveolar–arterial gradient 1211:FiO2 by Delivery Device 1243:Mechanical ventilation 962: 300: 963: 751:alveolar air equation 745:Alveolar air equation 301: 1033:Bitterman H (2009). 760: 150: 945: 908: 878: 844: 814: 786: 740:Related mathematics 694:Example calculation 437:intensive care unit 235: 207: 176: 1216:2015-09-20 at the 1095:(1): 202–7, e4-6. 958: 933: 896: 866: 832: 802: 774: 465:The ratio between 296: 223: 195: 164: 1126:"APACHE II Score" 951: 936: 899: 869: 847: 835: 805: 777: 393:In medicine, the 294: 291: 259: 226: 198: 167: 16:(Redirected from 1250: 1199: 1196: 1190: 1187: 1181: 1180: 1148: 1142: 1141: 1139: 1137: 1122: 1113: 1112: 1084: 1075: 1074: 1064: 1054: 1030: 1024: 1023: 1005: 981: 967: 965: 964: 959: 957: 953: 952: 947: 946: 944: 941: 934: 931: 930: 914: 909: 907: 904: 897: 894: 893: 879: 877: 874: 867: 864: 863: 848: 845: 843: 840: 833: 815: 813: 810: 803: 800: 799: 787: 785: 782: 775: 772: 771: 467:partial pressure 384: 383: 381: 380: 370: 367: 352: 337: 322: 305: 303: 302: 297: 295: 293: 292: 290: 289: 280: 279: 270: 261: 260: 258: 257: 248: 247: 238: 236: 234: 231: 224: 221: 220: 208: 206: 203: 196: 193: 192: 182: 177: 175: 172: 165: 162: 161: 133:partial pressure 21: 1258: 1257: 1253: 1252: 1251: 1249: 1248: 1247: 1228: 1227: 1223: 1218:Wayback Machine 1207: 1202: 1197: 1193: 1188: 1184: 1150: 1149: 1145: 1135: 1133: 1124: 1123: 1116: 1086: 1085: 1078: 1032: 1031: 1027: 983: 982: 978: 974: 922: 915: 885: 884: 880: 855: 791: 763: 758: 757: 747: 742: 734: 729: 723: 719: 715: 710: 704: 700: 685: 680: 674: 670: 659: 654: 648: 644: 625: 620: 614: 610: 606: 601: 595: 591: 587: 582: 576: 572: 555: 552: 547: 541: 537: 529: 524: 518: 514: 510: 505: 491: 486: 461: 449: 444: 431:is used in the 430: 425: 418: 403: 398: 391: 379: 371: 368: 366: 358: 357: 355: 354: 351: 347: 339: 336: 332: 324: 321: 317: 309: 281: 271: 262: 249: 239: 212: 184: 183: 153: 148: 147: 141: 130: 125: 119: 114: 100:oxygen toxicity 97: 92: 86: 81: 75: 70: 64: 59: 44: 39: 28: 23: 22: 15: 12: 11: 5: 1256: 1254: 1246: 1245: 1240: 1230: 1229: 1226: 1225: 1221: 1206: 1205:External links 1203: 1201: 1200: 1191: 1182: 1143: 1114: 1076: 1052:10.1186/cc7151 1025: 975: 973: 970: 969: 968: 956: 950: 940: 929: 925: 921: 918: 912: 903: 892: 888: 883: 873: 862: 858: 854: 851: 839: 830: 827: 824: 821: 818: 809: 798: 794: 790: 781: 770: 766: 746: 743: 741: 738: 737: 736: 732: 727: 721: 717: 713: 708: 702: 698: 695: 683: 678: 672: 668: 657: 652: 646: 642: 623: 618: 612: 608: 604: 599: 593: 589: 585: 580: 574: 570: 563:Horowitz index 554: 550: 545: 539: 535: 532: 527: 522: 516: 512: 508: 503: 489: 484: 475:arterial blood 462:will suffice. 459: 447: 442: 439:patients. For 428: 423: 417: 414: 401: 396: 390: 387: 375: 362: 349: 343: 334: 328: 319: 313: 307: 306: 288: 284: 278: 274: 268: 265: 256: 252: 246: 242: 230: 219: 215: 211: 202: 191: 187: 180: 171: 160: 156: 145: 140: 137: 128: 123: 117: 112: 105:Often used in 95: 90: 84: 79: 73: 68: 62: 57: 42: 37: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 1255: 1244: 1241: 1239: 1236: 1235: 1233: 1219: 1215: 1212: 1209: 1208: 1204: 1195: 1192: 1186: 1183: 1178: 1174: 1170: 1166: 1162: 1158: 1157:Crit Care Med 1154: 1147: 1144: 1131: 1127: 1121: 1119: 1115: 1110: 1106: 1102: 1098: 1094: 1090: 1089:Crit Care Med 1083: 1081: 1077: 1072: 1068: 1063: 1058: 1053: 1048: 1044: 1040: 1036: 1029: 1026: 1021: 1017: 1013: 1009: 1004: 999: 995: 991: 987: 980: 977: 971: 954: 948: 938: 927: 923: 919: 916: 910: 901: 890: 886: 881: 871: 860: 856: 852: 837: 828: 825: 822: 819: 807: 796: 792: 788: 779: 768: 764: 756: 755: 754: 752: 744: 739: 730: 711: 696: 693: 692: 691: 689: 681: 665: 663: 655: 639: 637: 633: 632:AECC criteria 629: 621: 602: 583: 568: 567:Carrico index 564: 560: 557:The ratio of 548: 533: 531: 525: 506: 499: 495: 487: 480: 476: 472: 468: 463: 457: 453: 445: 438: 434: 426: 415: 413: 411: 407: 399: 388: 386: 378: 374: 365: 361: 346: 342: 331: 327: 316: 312: 286: 282: 276: 272: 266: 263: 254: 250: 244: 240: 228: 217: 213: 209: 200: 189: 185: 178: 169: 158: 154: 146: 143: 142: 138: 136: 134: 126: 115: 108: 103: 101: 93: 82: 71: 60: 53: 49: 45: 40: 32: 19: 1194: 1185: 1163:(4): 721–6. 1160: 1156: 1146: 1136:21 September 1134:. 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MDCalc 1109:19050631 1071:19291278 1020:33750222 389:Medicine 107:medicine 1062:2688103 630:by the 410:alveoli 408:in the 382:⁠ 356:⁠ 1175:  1107:  1069:  1059:  1018:  1010:  481:) and 471:oxygen 338:, and 109:, the 52:oxygen 553:ratio 1173:PMID 1138:2017 1105:PMID 1067:PMID 1016:PMID 1008:ISSN 749:The 636:ARDS 479:PaO2 420:The 416:Uses 18:FiO2 1165:doi 1097:doi 1057:PMC 1047:doi 998:doi 994:320 667:A P 641:A P 565:or 473:in 469:of 1234:: 1171:. 1161:33 1159:. 1155:. 1128:. 1117:^ 1103:. 1093:37 1091:. 1079:^ 1065:. 1055:. 1043:13 1041:. 1037:. 1014:. 1006:. 992:. 988:. 868:CO 530:. 456:Pa 412:. 323:, 1222:2 1179:. 1167:: 1140:. 1111:. 1099:: 1073:. 1049:: 1022:. 1000:: 955:) 949:R 939:2 935:O 928:I 924:F 917:1 911:+ 902:2 898:O 891:I 887:F 882:( 872:2 861:A 857:P 850:) 846:O 838:2 834:H 829:P 823:B 820:P 817:( 808:2 804:O 797:I 793:F 789:= 780:2 776:O 769:A 765:P 733:2 731:O 728:I 726:F 724:/ 722:2 720:O 718:a 714:2 712:O 709:I 707:F 703:2 701:O 699:a 684:2 682:O 679:I 677:F 675:/ 673:2 671:O 669:a 658:2 656:O 653:I 651:F 649:/ 647:2 645:O 643:a 624:2 622:O 619:I 617:F 615:/ 613:2 611:O 609:a 605:2 603:O 600:I 598:F 596:/ 594:2 592:O 590:a 586:2 584:O 581:I 579:F 575:2 573:O 571:a 551:2 549:O 546:I 544:F 542:/ 540:2 538:O 536:a 534:P 528:2 526:O 523:I 521:F 519:/ 517:2 515:O 513:a 509:2 507:O 504:I 502:F 490:2 488:O 485:I 483:F 477:( 460:2 458:O 448:2 446:O 443:I 441:F 429:2 427:O 424:I 422:F 402:2 400:O 397:I 395:F 377:t 373:V 369:/ 364:D 360:V 350:2 348:O 345:I 341:P 335:2 333:O 330:E 326:P 320:2 318:O 315:A 311:P 287:t 283:V 277:D 273:V 264:1 255:t 251:V 245:D 241:V 229:2 225:O 218:I 214:P 201:2 197:O 190:E 186:P 179:= 170:2 166:O 159:A 155:P 129:2 127:O 124:I 122:F 118:2 116:O 113:I 111:F 96:2 94:O 91:I 89:F 85:2 83:O 80:I 78:F 74:2 72:O 69:I 67:F 63:2 61:O 58:I 56:F 48:I 43:2 41:O 38:I 36:F 33:( 20:)

Index

FiO2
oxygen
oxygen toxicity
medicine
partial pressure
gas exchange
alveoli
APACHE II
intensive care unit
alveolar–arterial gradient
partial pressure
oxygen
arterial blood
PaO2
hypoxemia
lung injury
partial pressure arterial oxygen
Horowitz index
acute respiratory distress syndrome
AECC criteria
ARDS
community acquired pneumonia
SMART-COP
alveolar air equation
"i stands for internet (and other things), not for inspired O 2 concentration"
doi
10.1152/ajplung.00610.2020
ISSN
1040-0605
PMID

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