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Acute panmyelosis with myelofibrosis

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Thiele J, Kvasnicka HM, Zerhusen G, et al. (August 2004). "Acute panmyelosis with myelofibrosis: a clinicopathological study on 46 patients including histochemistry of bone marrow biopsies and follow-up".
1026: 399: 506: 947: 657: 610: 511: 435: 806: 516: 208:"Long-term follow-up of autologous peripheral blood stem cell transplantation in the treatment of a patient with acute panmyelosis with myelofibrosis" 927: 583: 942: 667: 428: 1149: 932: 843: 672: 1016: 130: 784: 645: 543: 1124: 1059: 595: 521: 1109: 890: 826: 774: 762: 533: 501: 421: 1021: 836: 788: 727: 448: 118: 912: 878: 578: 605: 51:) is a poorly defined disorder that arises as either a clonal disorder, or following toxic exposure to the 1082: 868: 752: 717: 635: 568: 491: 331: 207: 114: 1119: 72: 1041: 1031: 937: 238: 388: 986: 900: 310: 266: 167:"Acute panmyelosis with myelofibrosis: an entity distinct from acute megakaryoblastic leukemia" 1036: 991: 302: 258: 219: 188: 27: 413: 294: 250: 178: 1097: 393: 1143: 692: 624: 341: 64: 270: 1007: 996: 314: 87: 79: 254: 976: 462: 336: 52: 378: 298: 183: 166: 68: 32: 78:
Clinically, patients present with reduction in the count of all blood cells (
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Ngirabacu MC, Ravoet C, Dargent JL, et al. (December 2006).
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Autologous stem cell transplantation has been used in treatment.
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Controversy remains today whether this disorder is a subtype of
94: 417: 82:), very few blasts in the peripheral blood, and no or little 1027:
Adult type of generalized eruption of cutaneous mastocytosis
121:; however, it is currently classified as a form of AML. 237:
Thiele J, Kvasnicka HM, Schmitt-Graeff A (April 2004).
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Orazi A, O'Malley DP, Jiang J, et al. (May 2005).
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Hoffman R, Benz E, Shattil S, Furie B, Cohen H (2004).
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Churchill Livingstone. 7: 1093:Acute panmyelosis with myelofibrosis 943:Paroxysmal nocturnal haemoglobinuria 45:Acute panmyelosis with myelofibrosis 22:Acute panmyelosis with myelofibrosis 14: 668:Juvenile myelomonocytic leukemia 933:Chromosome 5q deletion syndrome 844:Acute megakaryoblastic leukemia 673:Chronic myelomonocytic leukemia 584:Myeloid dendritic cell leukemia 1017:Diffuse cutaneous mastocytosis 131:List of hematologic conditions 1: 785:Chronic eosinophilic leukemia 544:Chronic neutrophilic leukemia 1125:Biphenotypic acute leukaemia 1060:Xanthelasmoidal mastocytosis 255:10.1080/10428190310001625692 502:Acute myeloblastic leukemia 63:Bone biopsy shows abnormal 1166: 1022:Erythrodermic mastocytosis 837:Essential thrombocythaemia 789:Hypereosinophilic syndrome 449:haematological malignancy 299:10.1007/s00277-004-0881-8 184:10.1038/modpathol.3800348 119:myelodysplastic syndromes 606:Philadelphia chromosome 101:Prognosis and treatment 1150:Acute myeloid leukemia 332:Acute myeloid leukemia 115:acute myeloid leukemia 1120:Primary myelofibrosis 1052:Systemic mastocytosis 997:Systemic mastocytosis 1042:Solitary mastocytoma 1032:Urticaria pigmentosa 938:Sideroblastic anemia 218:(12 Suppl): ECR53. 987:Mast cell leukemia 901:Polycythaemia vera 879:Erythroleukemia/M6 763:Acute eosinophilic 93:Cells are usually 59:Signs and symptoms 1137: 1136: 1133: 1132: 1068: 1067: 1037:Mast cell sarcoma 992:Mast cell sarcoma 960: 959: 956: 955: 923:Refractory anemia 852: 851: 801: 800: 797: 796: 736: 735: 701: 700: 681: 680: 619: 618: 552: 551: 411: 410: 42: 41: 16:Medical condition 1157: 1113: 1086: 1077: 1073:Multiple/unknown 1053: 1010: 980: 971: 916: 894: 872: 863: 830: 821: 812: 778: 756: 747: 728:Acute basophilic 721: 712: 661: 639: 630: 599: 572: 563: 537: 495: 486: 477: 468: 438: 431: 424: 415: 353: 319: 318: 281: 275: 274: 234: 228: 227: 203: 197: 196: 186: 162: 156: 155: 147: 19: 1165: 1164: 1160: 1159: 1158: 1156: 1155: 1154: 1140: 1139: 1138: 1129: 1107: 1102: 1098:Myeloid sarcoma 1080: 1064: 1051: 1046: 1006: 1001: 974: 952: 910: 905: 888: 883: 866: 848: 824: 793: 772: 767: 750: 732: 715: 697: 677: 655: 650: 633: 615: 593: 588: 566: 548: 531: 526: 489: 460: 451: 442: 412: 407: 406: 364: 350: 328: 323: 322: 283: 282: 278: 236: 235: 231: 205: 204: 200: 164: 163: 159: 149: 148: 144: 139: 127: 111: 103: 61: 17: 12: 11: 5: 1163: 1161: 1153: 1152: 1142: 1141: 1135: 1134: 1131: 1130: 1128: 1127: 1122: 1116: 1114: 1104: 1103: 1101: 1100: 1095: 1089: 1087: 1074: 1070: 1069: 1066: 1065: 1063: 1062: 1056: 1054: 1048: 1047: 1045: 1044: 1039: 1034: 1029: 1024: 1019: 1013: 1011: 1003: 1002: 1000: 999: 994: 989: 983: 981: 968: 962: 961: 958: 957: 954: 953: 951: 950: 945: 940: 935: 930: 925: 919: 917: 907: 906: 904: 903: 897: 895: 885: 884: 882: 881: 875: 873: 860: 854: 853: 850: 849: 847: 846: 840: 839: 833: 831: 818: 809: 803: 802: 799: 798: 795: 794: 792: 791: 781: 779: 769: 768: 766: 765: 759: 757: 744: 738: 737: 734: 733: 731: 730: 724: 722: 709: 703: 702: 699: 698: 696: 695: 689: 687: 683: 682: 679: 678: 676: 675: 670: 664: 662: 652: 651: 649: 648: 642: 640: 627: 621: 620: 617: 616: 614: 613: 608: 602: 600: 590: 589: 587: 586: 581: 575: 573: 560: 554: 553: 550: 549: 547: 546: 540: 538: 528: 527: 525: 524: 519: 514: 509: 504: 498: 496: 483: 474: 465: 453: 452: 443: 441: 440: 433: 426: 418: 409: 408: 405: 404: 396: 381: 365: 360: 359: 357: 356:Classification 349: 348:External links 346: 345: 344: 339: 334: 327: 324: 321: 320: 276: 243:Leuk. Lymphoma 229: 198: 157: 141: 140: 138: 135: 134: 133: 126: 123: 110: 107: 102: 99: 65:megakaryocytes 60: 57: 40: 39: 30: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1162: 1151: 1148: 1147: 1145: 1126: 1123: 1121: 1118: 1117: 1115: 1112: 1111: 1105: 1099: 1096: 1094: 1091: 1090: 1088: 1085: 1084: 1078: 1075: 1071: 1061: 1058: 1057: 1055: 1049: 1043: 1040: 1038: 1035: 1033: 1030: 1028: 1025: 1023: 1020: 1018: 1015: 1014: 1012: 1009: 1004: 998: 995: 993: 990: 988: 985: 984: 982: 979: 978: 972: 969: 967: 963: 949: 946: 944: 941: 939: 936: 934: 931: 929: 926: 924: 921: 920: 918: 915: 914: 908: 902: 899: 898: 896: 893: 892: 886: 880: 877: 876: 874: 871: 870: 864: 861: 859: 855: 845: 842: 841: 838: 835: 834: 832: 829: 828: 822: 819: 817: 813: 810: 808: 804: 790: 786: 783: 782: 780: 777: 776: 770: 764: 761: 760: 758: 755: 754: 748: 745: 743: 739: 729: 726: 725: 723: 720: 719: 713: 710: 708: 704: 694: 693:Histiocytosis 691: 690: 688: 684: 674: 671: 669: 666: 665: 663: 660: 659: 653: 647: 644: 643: 641: 638: 637: 631: 628: 626: 625:Myelomonocyte 622: 612: 609: 607: 604: 603: 601: 598: 597: 591: 585: 582: 580: 577: 576: 574: 571: 570: 564: 561: 559: 555: 545: 542: 541: 539: 536: 535: 529: 523: 520: 518: 515: 513: 510: 508: 505: 503: 500: 499: 497: 494: 493: 487: 484: 482: 478: 475: 473: 469: 466: 464: 458: 454: 450: 446: 439: 434: 432: 427: 425: 420: 419: 416: 402: 401: 397: 395: 391: 390: 386: 382: 380: 376: 375: 371: 367: 366: 363: 358: 354: 347: 343: 342:Myelofibrosis 340: 338: 335: 333: 330: 329: 325: 316: 312: 308: 304: 300: 296: 293:(8): 513–21. 292: 288: 280: 277: 272: 268: 264: 260: 256: 252: 248: 244: 240: 233: 230: 225: 221: 217: 213: 212:Haematologica 209: 202: 199: 194: 190: 185: 180: 177:(5): 603–14. 176: 172: 168: 161: 158: 153: 146: 143: 136: 132: 129: 128: 124: 122: 120: 116: 108: 106: 100: 98: 96: 91: 89: 86:enlargement ( 85: 81: 76: 74: 73:myelofibrosis 70: 66: 58: 56: 54: 50: 46: 38: 34: 31: 29: 25: 20: 1108: 1092: 1081: 1008:Mastocytosis 975: 911: 889: 867: 825: 773: 751: 716: 656: 634: 594: 567: 532: 490: 463:granulocytes 398: 383: 368: 290: 287:Ann. Hematol 286: 279: 249:(4): 681–7. 246: 242: 232: 215: 211: 201: 174: 170: 160: 151: 145: 112: 104: 92: 88:splenomegaly 80:pancytopenia 77: 62: 48: 44: 43: 977:Mastocytoma 337:Panmyelosis 171:Mod. Pathol 109:Terminology 53:bone marrow 461:and other 137:References 97:positive. 69:neutrophil 33:Hematology 481:Myelocyte 447:-related 28:Specialty 1144:Category 966:CFU-Mast 707:CFU-Baso 558:Monocyte 403:: 9931/3 326:See also 307:15173958 271:20626984 263:15160939 224:17194659 193:15578075 125:See also 37:oncology 816:CFU-Meg 742:CFU-Eos 579:AMoL/M5 445:Myeloid 315:2422812 522:APL/M3 472:CFU-GM 457:CFU-GM 394:238.79 313:  305:  269:  261:  222:  191:  84:spleen 858:CFU-E 686:Other 658:MD-MP 400:ICD-O 379:C94.4 311:S2CID 267:S2CID 389:9-CM 303:PMID 259:PMID 220:PMID 189:PMID 95:CD34 49:APMF 1083:AML 869:AML 807:MEP 753:AML 718:AML 636:AML 596:CML 569:AML 492:AML 385:ICD 370:ICD 295:doi 251:doi 179:doi 117:or 90:). 75:). 1146:: 1110:MP 913:MD 891:MP 827:MP 775:MP 646:M4 534:MP 517:M2 512:M1 507:M0 392:: 377:: 374:10 309:. 301:. 291:83 289:. 265:. 257:. 247:45 245:. 241:. 216:91 214:. 210:. 187:. 175:18 173:. 169:. 55:. 35:, 787:/ 459:/ 437:e 430:t 423:v 387:- 372:- 362:D 317:. 297:: 273:. 253:: 226:. 195:. 181:: 47:(

Index

Specialty
Hematology
oncology
bone marrow
megakaryocytes
neutrophil
myelofibrosis
pancytopenia
spleen
splenomegaly
CD34
acute myeloid leukemia
myelodysplastic syndromes
List of hematologic conditions
"Acute panmyelosis with myelofibrosis: an entity distinct from acute megakaryoblastic leukemia"
doi
10.1038/modpathol.3800348
PMID
15578075
"Long-term follow-up of autologous peripheral blood stem cell transplantation in the treatment of a patient with acute panmyelosis with myelofibrosis"
PMID
17194659
"Acute panmyelosis with myelofibrosis"
doi
10.1080/10428190310001625692
PMID
15160939
S2CID
20626984
doi

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