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91:. Because of this, researchers had a difficult time concluding that type of tumor has a mesothelial origin. Immunohistochemistry staining of tumor samples show that it is indeed positive for mesothelial-markers (calretinin, WT1, and CK6). It is the most common extratesticular neoplasm after lipoma, and accounts for 30% of these masses. On the other hand, adenomatoid tumors are the most common tumors of testicular adnexa. Although they are more common to be found in the paratesticular region they are sometimes found in the intratesticular region. It also has been found in other organs such as the
61:
29:
252:
222:. Ultrasonically can help identify if it fits this category or not. This specific characteristic in adenomatoid tumors is variable and can determine whether or not ultrasound is the right technique for the job. Having other options available to identify the tumor helps fill in the gap when ultrasound is not possible. MRI and CT imaging are usually helpful when scanning the adrenal gland for tumors.
142:
111:. Most adenomatoid tumors do not cause much pain and can go unnoticed for a long time. Of course, there are a few exceptions to this absence of pain. An example of this is when adenomatoid tumors grow too close to testicular adnexal structures. Tumors of this kind are usually found to be asymptomatic and easily treatable.
119:
While adenomatoid tumors are present in both the various body areas of males and females, one study discovered that these tumors were more likely to occur in
Caucasian males. Adenomatoid tumors can be found in a widespread age of people ranging from 18 to 79 years old. Most of these tumors are not
217:
scans are all used to identify whether a patient has adenomatoid tumors. The shape, location, and activity of the tumor are all important information to attain. Each imaging modality has its own strengths and weaknesses. Dynamic contrast enhanced MRI can differentiate tumors from disorders in the
130:
120:
spotted until about the 30s. This asymptomatic nature is due to the fact that a majority of adenomatoid tumors grow silently and are sometimes dormant without causing any pain. This is what contributes to the difficulty of catching adenomatoid tumors.
123:
These benign tumors can grow up to 5.0 centimeters (most of them range around to 2.0 cm). Although adenomatoid tumors are not known to infiltrate surrounding tissues, it is possible that there are multiple adenomatoid tumors in the same area.
336:
235:
is usually done on the patient. Though this can be used as both a diagnostic and removal procedure, it has proven to be effective. Successful procedures results in a tumor free area that is not prone recur.
230:
If located in the testes region, removal of the tumor must be handled with great care to prevent damage to testosterone production and keep the patient fertile. If removal of the tumor is necessary then an
218:
testicular region. Misdiagnosing something can sometimes cause more damage then doing nothing. One weakness of adenomatoid tumor ultrasound imaging is that it is only possible if the tumor is
768:
1303:
656:
Garg, Karuna; Lee, Peng; Ro, J.Y.; Qu, Zhenhong; Troncoso, Patricia; Ayala, Alberto G. (February 2005). "Adenomatoid tumor of the adrenal gland: a clinicopathologic study of 3 cases".
365:
Cassidy, Fiona Hughes; Ishioka, Kevin M.; McMahon, Colm J.; Chu, Pauline; Sakamoto, Kyoko; Lee, Karen S.; Aganovic, Lejla (May 2010). "MR Imaging of
Scrotal Tumors and Pseudotumors".
203:
In order to see adenomatoid tumors multiple imaging modalities are used. These tumors appear to be small, solid, and circumscribed with a color that usually ranges from white to tan.
344:
710:
1323:
308:
1439:
761:
148:
High magnification of the same case, showing the typical features of tubular spaces of varying size composed of flattened cells resembling endothelium.
754:
565:
187:
Adenomatoid tumors of the female and male genital tract are characterized by somatic missense mutations in the TRAF7 gene, which leads to aberrant
179:
pathway activation, has been shown to be expressed in adenomatoid tumors (and negative in other benign mesothelial tissues and mesothelioma).
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879:
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507:
Huang CC, Chang DY, Chen CK, Chou YY, Huang SC (Sep 1995). "Adenomatoid tumor of the female genital tract".
1173:
1024:
981:
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28:
83:, which arise from the lining of organs. It mainly presents in the genital tract, in regions such as the
573:
402:"Adenomatoid tumor of the pancreas: a case report with comparison of histology and aspiration cytology"
239:
When used as a diagnosis tool, the excision biopsy can collect a tissue sample from the tumor. Through
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1205:
929:
857:
136:
An adenomatoid tumor of the fallopian tube, low magnification, displaying infiltrative-like borders.
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Given their mesothelial origin, the cells lining the spaces are positive for cytokeratins,
1229:
1057:
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pathway activation. Unlike some malignant mesotheliomas, adenomatoid tumors do not harbor
1365:
1390:
1380:
1298:
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1047:
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Gynecologic pathology : a volume in the series
Foundations in diagnostic pathology
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1408:
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Williams SB, Han M, Jones R, Andrawis R (2004). "Adenomatoid tumor of the testes".
566:"Fallopian tubes & broad ligament - Fallopian tube tumors - Adenomatoid tumor"
286:
41:
723:
1400:
1238:
1112:
1107:
1007:
781:
219:
77:
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Pathology and genetics of tumours of the urinary system and male genital organs
1345:
1194:
206:
168:
88:
37:
642:
475:
1271:
1214:
1163:
729:
551:"Testicular Adenomatoid Tumor Pathology: Definition, Epidemiology, Etiology"
240:
171:. They are negative for MOC31, BerEP4, and vascular markers (CD31 or CD34).
677:
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427:
386:
294:
528:
784:
378:
92:
54:
467:
867:
840:
788:
623:
World Health
Organization. International Academy of Pathology. (2004).
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expression is retained. L1 cell adhesion molecule (L1CAM), a marker of
702:
593:
591:
1103:
1003:
995:
232:
192:
104:
84:
74:
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Overstreet K, Wixom C, Shabaik A, Bouvet M, Herndier B (Jun 2003).
1190:
585:
Topic
Completed: 1 September 2013. Minor changes: 13 December 2019
250:
188:
176:
96:
80:
734:
172:
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evaluation the lesion can be categorized in the patients.
1304:
Multiple cutaneous and uterine leiomyomatosis syndrome
103:. In the female, it has been found in the body of the
337:"Adenomatoid Tumor - American Urological Association"
692:
1399:
1336:
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1172:
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1038:
994:
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48:
21:
450:Amin, Waqas; Parwani, Anil V. (January 2009).
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8:
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836:
827:
769:
755:
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693:
59:
27:
18:
483:
417:
265:
126:
309:"Adenomatoid tumor of the epididymis"
7:
1440:Connective and soft tissue neoplasms
598:Nucci, Marisa R. (3 February 2020).
445:
443:
441:
439:
437:
331:
329:
255:Adenomatoid tumour of the epididymis
808:Desmoplastic small-round-cell tumor
14:
885:Aggressive infantile fibromatosis
670:10.1053/j.anndiagpath.2004.10.003
419:10.1097/01.MP.0000072803.37527.C8
1376:Clear-cell sarcoma of the kidney
602:(Second ed.). p. 490.
141:
129:
1144:Intradermal spindle cell lipoma
853:Dermatofibrosarcoma protuberans
972:Malignant fibrous histiocytoma
920:Infantile digital fibromatosis
905:Familial myxovascular fibromas
900:Diffuse infantile fibromatosis
658:Annals of Diagnostic Pathology
564:Nicole Riddle, Jamie Shutter.
1:
1018:Superficial acral fibromyxoma
925:Juvenile hyaline fibromatosis
452:"Adenomatoid Tumor of Testis"
287:10.1016/j.urology.2003.11.035
1319:Solitary cutaneous leiomyoma
1309:Multiple cutaneous leiomyoma
1030:Ossifying fibromyxoid tumour
521:10.1016/0020-7292(95)02453-J
456:Clinical Medicine. Pathology
967:Benign fibrous histiocytoma
1456:
1247:Embryonal rhabdomyosarcoma
823:Connective tissue neoplasm
1371:Malignant rhabdoid tumour
1338:Complex mixed and stromal
1267:
1259:Alveolar rhabdomyosarcoma
40:of an adenomatoid tumor.
35:
26:
910:Fibroma of tendon sheath
940:Oral submucous fibrosis
880:Aggressive fibromatosis
796:Not otherwise specified
195:deleterious mutations.
982:Solitary fibrous tumor
977:Atypical fibroxanthoma
256:
1356:Mixed Müllerian tumor
509:Int J Gynaecol Obstet
254:
1361:Mesoblastic nephroma
930:Plantar fibromatosis
858:Desmoplastic fibroma
379:10.1148/rg.303095049
159:Immunohistochemistry
1351:Pleomorphic adenoma
1159:Spindle cell lipoma
959:histiocytic sarcoma
935:Pleomorphic fibroma
895:Collagenous fibroma
890:Aponeurotic fibroma
803:Soft-tissue sarcoma
468:10.4137/cpath.s3091
36:High-magnification
1314:Neural fibrolipoma
1289:Angiolipoleiomyoma
1252:Sarcoma botryoides
1149:Pleomorphic lipoma
1118:Myxoid liposarcoma
1082:Clear-cell sarcoma
915:Fibromatosis colli
570:Pathology Outlines
257:
183:Molecular analysis
71:Adenomatoid tumors
1422:
1421:
1414:Adenomatoid tumor
1386:Pancreatoblastoma
1332:
1331:
1294:Genital leiomyoma
1154:Lipoblastomatosis
1090:
1089:
990:
989:
945:Pachydermodactyly
744:
743:
609:978-0-323-35909-2
247:Additional images
154:Ancillary Studies
99:, mesocolon, and
68:
67:
22:Adenomatoid tumor
16:Medical condition
1447:
1435:Benign neoplasms
1243:rhabdomyosarcoma
1232:
1208:
1184:
1179:
1139:Chondroid lipoma
1077:Synovial sarcoma
1013:Cutaneous myxoma
837:
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572:. Archived from
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343:. Archived from
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311:. Archived from
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31:
19:
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1230:Skeletal muscle
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1058:Phyllodes tumor
1040:Fibroepithelial
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233:excision biopsy
228:
201:
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137:
134:
117:
58:
17:
12:
11:
5:
1453:
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1437:
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1420:
1419:
1417:
1416:
1411:
1405:
1403:
1397:
1396:
1394:
1393:
1391:Carcinosarcoma
1388:
1383:
1381:Hepatoblastoma
1378:
1373:
1368:
1363:
1358:
1353:
1348:
1342:
1340:
1334:
1333:
1330:
1329:
1327:
1326:
1321:
1316:
1311:
1306:
1301:
1299:Leiomyosarcoma
1296:
1291:
1286:
1284:Angioleiomyoma
1281:
1280:
1279:
1268:
1265:
1264:
1262:
1261:
1256:
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1235:
1233:
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1219:leiomyosarcoma
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1167:
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1130:Angiomyolipoma
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1048:Brenner tumour
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697:Classification
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689:External links
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627:. IARC Press.
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373:(3): 665–683.
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109:fallopian tube
101:adrenal glands
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634:92-832-2412-4
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576:on 2021-10-18
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553:. 2019-11-26.
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515:(3): 275–80.
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367:RadioGraphics
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347:on 2020-07-16
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315:on 2007-06-15
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281:(4): 779–81.
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167:, D2-40, and
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73:are rare and
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56:
53:
51:
47:
43:
42:H&E stain
39:
34:
30:
25:
20:
1413:
1409:Mesothelioma
1366:Wilms' tumor
1053:Fibroadenoma
955:Histiocytoma
872:fibromatosis
845:fibrosarcoma
813:Skin sarcoma
728:
717:
709:
664:(1): 11–15.
661:
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624:
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599:
578:. Retrieved
574:the original
569:
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508:
502:
459:
455:
412:(6): 613–7.
409:
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349:. Retrieved
345:the original
340:
317:. Retrieved
313:the original
303:
278:
274:
268:
241:histological
238:
229:
205:
202:
186:
162:
122:
118:
70:
69:
1401:Mesothelial
1239:Rhabdomyoma
1113:Myelolipoma
1108:liposarcoma
1025:Angiomyxoma
1008:myxosarcoma
832:Fibromatous
782:soft tissue
406:Mod. Pathol
220:hyperechoic
78:mesothelial
1429:Categories
1346:Adenomyoma
1195:myosarcoma
1096:Lipomatous
996:Myxomatous
778:Connective
580:2020-10-16
351:2020-04-24
319:2007-12-15
260:References
207:Ultrasound
169:calretinin
89:epididymis
38:micrograph
1277:Cutaneous
1272:Leiomyoma
1215:Leiomyoma
1174:Myomatous
1164:Hibernoma
730:SNOMED CT
643:934111854
476:1178-1181
462:: 17–22.
226:Treatment
115:Pathology
50:Specialty
1068:Synovial
789:sarcomas
714:: 9054/0
678:15692945
537:39868984
494:21151545
428:12808068
387:20462987
295:15072910
107:and the
93:pancreas
55:Oncology
1183:General
868:Fibroma
841:Fibroma
735:2348006
724:D018254
529:8543111
485:2990235
275:Urology
199:Imaging
1125:PEComa
1104:Lipoma
1004:Myxoma
785:tumors
676:
641:
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474:
426:
385:
293:
213:, and
193:CDKN2A
105:uterus
85:testis
81:tumors
75:benign
57:
1324:STUMP
1191:Myoma
1070:-like
711:ICD-O
533:S2CID
189:NF-kB
177:NF-kB
97:liver
787:and
719:MeSH
674:PMID
639:OCLC
629:ISBN
604:ISBN
525:PMID
490:PMID
472:ISSN
424:PMID
383:PMID
291:PMID
173:BAP1
87:and
666:doi
517:doi
480:PMC
464:doi
414:doi
375:doi
283:doi
211:MRI
165:WT1
1431::
1245::
733::
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637:.
590:^
568:.
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523:.
513:50
511:.
488:.
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436:^
422:.
410:16
408:.
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381:.
371:30
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328:^
289:.
279:63
277:.
215:CT
209:,
95:,
1241:/
1217:/
1193:/
1106:/
1006:/
957:/
870:/
843:/
780:/
770:e
763:t
756:v
703:D
680:.
668::
662:9
645:.
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583:.
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466::
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416::
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285::
44:.
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