71:
103:). All ATL cells contain integrated HTLV-1 provirus further supporting that causal role of the virus in the cause of the neoplasm. A small amount of HTLV-1 individuals progress to develop ATL with a long latency period between infection and ATL development. ATL is categorized into 4 subtypes: acute, smoldering, lymphoma-type, chronic. Acute and Lymphoma-type are known to particularly be aggressive with poorer prognosis.
43:
291:. The overall incidence of ATL is estimated at 1 per 1,500 adult HTLV-1 carriers per year. Those cases that have been reported have occurred mostly among persons from the Caribbean or African Americans from the Southeast United States (National Institutes of Health, unpublished data). There appears to be a long latent period between
204:
lymphoma, chronic, smoldering. Normally, identification of at least 5 percent of tumor cells in peripheral blood and confirmation of human T-lymphotropic virus type-1 are sufficient for diagnosis of acute, chronic, and smoldering types. For the lymphoma type, histopathologic examination by biopsy of lymph nodes may be needed.
110:
Current treatment regiments for ATL are based on clinical subtype and response to initial therapy. Some therapy modalities for treatment may not available in all countries therefore strategies differ across the world. All patients are referred to clinical trials if available. Beyond clinical trials,
163:
induced bone disease is that the bone lesions are predominantly osteolytic with little associated osteoblastic activity. In patients with ATL, elevated serum levels of IL-1, TGFβ, PTHrP, macrophage inflammatory protein (MIP-1α), and receptor activator of nuclear factor-κB ligand (RANKL) have been
203:
Diagnosis is made based on the combination of clinical features, characteristic morphologic and immunophenotypic changes of malignant cells. As clinical features and prognosis can be diverse, the disease is subtype-classified into four categories according to the
Shimoyama classification: acute,
106:
Globally, the retrovirus HTLV-1 is estimated to infect 20 million people per year with the incidence of ATL approximately 0.05 per 100,000 per year with endemic regions such as regions of Japan, as high as 27 per 100,000 per year. However, cases have increased in non-endemic regions with highest
107:
incidence of HTLV-1 in southern/northern islands of Japan, Caribbean, Central and South
America, intertropical Africa, Romania, northern Iran. ATL normally occurs around the age of 62 years but median age at diagnosis does depend on prevalence of the HTLV-1 infection in the geographic location.
228:
has also been investigated. Recently, it has been reported that the traditional glucocorticoid-based chemotherapy toward ATL are largely mediated by thioredoxin binding protein-2 (TBP-2/TXNIP/VDUP1), suggesting the potential use of a TBP-2 inducer as a novel therapeutic target.
164:
associated with hypercalcemia. Immunodeficient mice that received implants with leukemic cells from patients with ATL or with HTLV-1–infected lymphocytes developed hypercalcemia and elevated serum levels of PTHrP. Most patients die within one year of diagnosis.
1384:
1365:
1195:
Campuzano-Zuluaga, G; Pimentel, A; Diaz, L; Chapman-Fredricks, J; and Ramos, J (2013). "CD30 Expression Is
Associated With Decreased Survival In Patients With Acute and Unfavorable Chronic Types Of Adult T-Cell Leukemia-Lymphoma"
155:, features of bone metastases, commonly occur in the setting of advanced solid tumors, such as breast, prostate, and lung cancers, but are less common in hematologic malignancies. However, patients with HTLV-1–induced ATL and
207:
The immunophenotype of ATLL includes positive markers such as CD2, CD3, CD4, CD5, and CD25, with negative markers for CD7, CD8, and cytotoxic markers. Additionally, there is partial positivity for CD30, CCR4, and FOXP3.
2379:
1115:
Chen, Z; Yoshihara E (2010). "Differential roles of
Annexin A1 (ANXA1/lipocortin-1/lipomodulin) and thioredoxin binding protein-2 (TBP-2/VDUP1/TXNIP) in glucocorticoid signaling of HTLV-I-transformed T cells".
2123:
259:
data exist, the prevalence of infection is thought to be highest among
African-Americans living in the Southeast. A prevalence rate of 30% has been found among African-American intravenous drug users in
239:
At a medical conference in
December 2013, researchers reported anywhere from 21 to 50% of ATL patients have disease expressing CD30. Although not FDA approved, treatment with CD30-targeting
1677:
3416:
1270:
Franchini, Genoveffa; Nicot, Christophe; Johnson, Julie M. (2003). "Seizing of T Cells by Human T-Cell
Leukemia/Lymphoma Virus Type 1". In Vande Woude, George F.; Klein, George (eds.).
3854:
1794:
1403:
936:"A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303: A New G-CSF-Supported Chemotherapy for ATL"
2384:
2193:
778:
2839:
2407:
1759:
2149:
3430:
1488:
268:. It is possible that the prevalence of infection is increasing in this risk group. Studies of HTLV-1 antibody indicate that the virus is endemic in southern
111:
treatments are centered on multiagent chemotherapy, zidovudine plus interferon a (AZT/IFN), and allogenic hematopoietic stem cell transplantation (alloHSCT).
1839:
2352:
3096:
2391:
1937:
1682:
2927:
1816:
2967:
1917:
1715:
2341:
2015:
1569:
2188:
2832:
2460:
2007:
1558:
1289:
671:
Ishida, T; Joh, T; Uike, N; Yamamoto, K; Utsunomiya, A; Yoshida, S; Saburi, Y; Miyamoto, T; Takemoto, S; Suzushima, H; Tsukasaki, K (2012).
3060:
2336:
1027:"Pralatrexate-induced tumor cell apoptosis in the epidermis of a patient with HTLV-1 adult T-cell lymphoma/leukemia causing skin erosions"
139:
causes ATL. This evidence includes the frequent isolation of HTLV-1 from patients with this disease and the detection of HTLV-1 proviral
3839:
3117:
2292:
1912:
1710:
1594:
1068:"Thioredoxin-binding protein-2 (TBP-2/VDUP1/TXNIP) regulates T-cell sensitivity to glucocorticoid during HTLV-I-induced transformation"
2183:
3436:
2962:
2919:
1481:
1209:
Cook, L; Fuji, S; Hermine, O; Bazarbachi, A; Ramos, J; Ratner, L; Horwitz, S; Fields, P; Tanase, A; Bumbea, H; Cwynarski, K (2019).
3351:
934:
Yamada, Y; Tomonaga, M; Fukuda, H; Hanada, S; Utsunomiya, A; Tara, M; Sano, M; Ikeda, S; Takatsuki, K; Kozuru, M; Araki, K (2001).
2144:
1332:
3422:
2825:
673:"Defucosylated anti-CCR4 monoclonal antibody (KW-0761) for relapsed adult T-cell leukemia-lymphoma: a multicenter phase II study"
1025:
Marneros, A; Grossman, M; Silvers, D; Husain, S; Nuovo, G; Macgregor-Cortelli, B; Neylon, E; Patterson, M; O'Connor, O (2009).
3844:
3007:
2469:
2374:
2366:
2042:
2028:
1922:
1863:
1700:
1626:
770:
2422:
2332:
2282:
2178:
1907:
1691:
847:
159:
are predisposed to the development of tumor-induced osteolysis and hypercalcemia. One of the striking features of ATL and
191:
is believed to occur from mother to child; by sexual contact; and through exposure to contaminated blood, either through
3226:
3220:
3131:
3125:
3015:
2538:
2314:
2220:
2203:
2011:
1565:
1474:
3589:
3515:
3509:
3182:
2764:
2718:
2255:
2128:
1834:
1309:"Adult T-cell leukemia/lymphoma associated with human T-lymphotropic virus type I (HTLV-I) infection--North Carolina"
2170:
3646:
3253:
2806:
2453:
2058:
1899:
1821:
120:
3355:
3267:
3172:
3002:
2975:
2947:
2880:
2502:
2260:
2088:
1414:
975:
Chavez, Julio C.; Flores, Laura E.; Khouri, Ricardo; Martin, Arthur; Campos, Leonardo; Castillo, Jorge (2023).
324:
Yodoi, J; Takatsuki, K; Masuda, T (1974). "Letter: Two cases of T-cell chronic lymphocytic leukemia in Japan".
135:
with an irregular nuclear contour (leukemic cells) are frequently seen. Several lines of evidence suggest that
1726:
803:
Taylor, G; Matsuoka, M (2005). "Natural history of adult T-cell leukemia/lymphoma and approaches to therapy".
722:"HTLV-1 Tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition"
616:"Increase in incidence of adult T-cell leukemia/lymphoma in non-endemic areas of Japan and the United States"
3151:
2519:
3345:
2941:
2277:
1828:
3545:
3523:
3402:
3398:
3394:
3390:
3283:
3177:
3138:
2567:
2154:
2133:
2047:
1454:
303:
Novel approaches to the treatment of PTCL in the relapsed or refractory setting are under investigation.
3849:
3530:
3111:
2981:
2713:
2592:
2531:
2507:
2286:
1876:
1770:
870:
2952:
1849:
1672:
1161:
Subramaniam, J; Whiteside, G; McKeage, K; Croxtall, J (2012). "Mogamulizumab: first global approval".
976:
3794:
3626:
3261:
3090:
2706:
2672:
2562:
2446:
2083:
1695:
1606:
3212:
2933:
2514:
2498:
2491:
1883:
1667:
1637:
1388:
240:
221:
70:
3315:
3071:
2555:
2543:
2347:
916:
593:
535:
477:
425:
2817:
614:
Chihara, D; Ito, H; Katanoda, K; Shibata, A; Matsuda, T; Tajima, K; Sobue, T; Matsuo, K (2012).
3859:
3779:
3730:
3711:
3692:
3482:
3478:
3474:
3470:
3387:
3292:
2996:
2874:
2694:
2427:
2097:
2078:
2067:
1857:
1747:
1662:
1425:
1320:
1295:
1285:
1248:
1230:
1178:
1143:
1097:
1048:
1004:
996:
957:
908:
900:
820:
751:
702:
694:
653:
635:
585:
577:
527:
519:
469:
417:
382:
341:
192:
55:
1197:
3754:
3464:
3144:
3076:
2957:
2888:
2197:
1976:
1844:
1743:
1466:
1277:
1238:
1222:
1170:
1133:
1125:
1087:
1079:
1038:
988:
947:
890:
882:
812:
741:
733:
684:
643:
627:
569:
511:
459:
409:
372:
333:
160:
156:
3678:
3606:
3601:
3583:
3503:
3492:
3363:
3327:
3247:
3033:
2894:
2650:
1970:
1965:
1774:
1658:
1524:
1519:
1308:
2438:
2914:
2587:
2417:
1408:
1243:
1210:
1092:
1067:
746:
721:
648:
615:
1397:
1393:
1281:
500:"Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation"
3833:
2909:
2904:
2852:
2660:
2655:
2324:
2023:
1932:
1888:
1705:
1579:
1174:
952:
935:
886:
631:
277:
252:
233:
144:
17:
920:
597:
481:
42:
3770:
3620:
3298:
3159:
2778:
2744:
2680:
1927:
1589:
539:
429:
304:
225:
176:
168:
720:
Gao, L; Deng, H; Zhao, H; Hirbe, A; Harding, J; Ratner, L; Weilbaecher, K (2005).
1419:
1043:
1026:
3810:
3759:
3747:
3742:
3735:
3723:
3718:
3697:
3667:
3569:
3408:
3320:
3303:
3238:
2899:
2783:
2689:
2665:
1601:
1129:
377:
360:
337:
265:
148:
1430:
1211:"Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report"
839:
737:
3660:
3444:
3201:
2802:
2759:
2730:
2725:
2612:
2604:
1497:
992:
573:
413:
400:
Yodoi, J; Maeda, M (2011). "The discovery of ATL: an odyssey in restrospect".
261:
217:
152:
143:
in ATL leukemic cells. ATL is frequently accompanied by visceral involvement,
132:
124:
64:
1234:
1000:
904:
698:
689:
672:
639:
581:
523:
3705:
3686:
3653:
3641:
3635:
3614:
3560:
3488:
3459:
3382:
3374:
3336:
3105:
3084:
2990:
2868:
2860:
2848:
2797:
2526:
2486:
1378:
1374:
557:
273:
256:
243:
in CD 30+ cases may be beneficial and supported by current NCCN guidelines.
128:
1299:
1252:
1182:
1147:
1101:
1052:
1008:
961:
912:
824:
816:
755:
706:
657:
589:
531:
473:
421:
1324:
345:
307:
is one compound currently under investigations for the treatment of PTCL.
3803:
3450:
3192:
3048:
2635:
2579:
2550:
2478:
2412:
2240:
1951:
1514:
1501:
1449:
1226:
1083:
499:
386:
172:
60:
3556:
2617:
1138:
895:
1357:
464:
447:
361:"Adult T-cell leukemia: Clinical and hematologic features of 16 cases"
3165:
2701:
1960:
1369:
292:
288:
281:
188:
140:
136:
100:
96:
92:
1271:
515:
448:"Current views in HTLV-I-associated adult T-cell leukemia/lymphoma"
3816:
3575:
3207:
2627:
1783:
1648:
1632:
359:
Uchiyama, T; Yodoi, J; Sagawa, K; Takatsuki, K; Uchino, H (1977).
269:
1273:
Seizing of T Cells by Human T-Cell
Leukemia⧸Lymphoma Virus Type 1
2246:
2140:
2119:
2037:
1779:
1754:
1734:
1730:
1617:
1535:
1530:
2821:
2442:
1470:
236:
was approved for relapsed/refractor treatment of ATL in Japan.
3042:
2640:
1986:
1981:
1871:
1276:. Advances in Cancer Research. Vol. 89. pp. 69–132.
127:
appearance except for a diffuse pattern and a mature T-cell
2124:
Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
771:"Treatment and prognosis of adult T cell leukemia-lymphoma"
99:
caused by human T cell leukemia/lymphotropic virus type 1 (
1198:
https://ash.confex.com/ash/2013/webprogram/Paper64702.html
264:, and a rate of 49% has been found in a similar group in
558:"Adult T Cell Leukemia-Lymphoma (ATL): State of the Art"
1333:
Human
Retroviral Diseases: Pathogenesis and Prevention
287:
ATL is relatively uncommon among those infected with
1347:
171:, probably occurs for life and can be inferred when
3793:
3769:
3677:
3600:
3555:
3544:
3373:
3335:
3314:
3282:
3237:
3191:
3070:
3059:
3032:
2859:
2741:
2626:
2603:
2578:
2477:
2400:
2365:
2323:
2305:
2269:
2239:
2212:
2167:
2112:
2066:
2057:
1997:
1959:
1950:
1898:
1808:
1769:
1725:
1647:
1616:
1578:
1557:
1546:
1513:
1440:
1351:
54:
35:
2194:Peripheral T-cell lymphoma not otherwise specified
1337:
2016:Precursor T acute lymphoblastic leukemia/lymphoma
1570:Precursor B acute lymphoblastic leukemia/lymphoma
167:Infection with HTLV-1, like infection with other
840:"HTLV-1: CLINICAL IMPACT OF A CHRONIC INFECTION"
1760:Nodular lymphocyte predominant Hodgkin lymphoma
1020:
1018:
798:
796:
216:Treatment options that have been tried include
441:
439:
2833:
2454:
2150:Secondary cutaneous CD30+ large-cell lymphoma
1482:
8:
3855:Sexually transmitted diseases and infections
1840:Post-transplant lymphoproliferative disorder
1795:immunoproliferative immunoglobulin disorders
977:"How I treat adult T-cell leukemia/lymphoma"
151:, and lytic bone lesions. Bone invasion and
2353:Diffuse infiltrative lymphocytosis syndrome
3552:
3332:
3097:Progressive multifocal leukoencephalopathy
3067:
2840:
2826:
2818:
2461:
2447:
2439:
2392:Jessner lymphocytic infiltrate of the skin
2063:
1994:
1956:
1938:Primary cutaneous follicle center lymphoma
1683:Primary cutaneous follicle center lymphoma
1554:
1543:
1510:
1489:
1475:
1467:
1348:
1307:Centers for Disease Control (CDC) (1987).
981:Surgical Oncology Clinics of North America
69:
41:
32:
2968:Extranodal NK/T-cell lymphoma, nasal type
1242:
1137:
1091:
1042:
951:
894:
745:
688:
647:
463:
376:
1918:Primary cutaneous marginal zone lymphoma
1716:Primary cutaneous marginal zone lymphoma
2380:with bandlike and perivascular patterns
2342:Autoimmune lymphoproliferative syndrome
1338:International Retrovirology Association
316:
2189:Enteropathy-associated T-cell lymphoma
562:Current Hematologic Malignancy Reports
1313:Morbidity and Mortality Weekly Report
7:
2337:X-linked lymphoproliferative disease
609:
607:
551:
549:
493:
491:
255:appears to be rare. Although little
195:or sharing of contaminated needles.
3118:Subacute sclerosing panencephalitis
2293:Large granular lymphocytic leukemia
1913:Intravascular large B-cell lymphoma
402:International Journal of Hematology
119:ATL is usually a highly aggressive
175:against HTLV-1 is detected in the
25:
3437:Severe acute respiratory syndrome
2963:Follicular dendritic cell sarcoma
2765:Pelvic inflammatory disease (PID)
556:Phillips, A; Harewood, J (2018).
3423:Middle East respiratory syndrome
1331:Genoveffa Franchini's NCI page:
1175:10.2165/11631090-000000000-00000
1066:Chen, Z; Lopez-Ramos, D (2011).
953:10.1046/j.1365-2141.2001.02737.x
887:10.1179/102453312X13336169155330
871:"Adult T-cell leukemia–lymphoma"
838:Gotuzzo, E; Verdonck, K (2004).
632:10.1111/j.1349-7006.2012.02373.x
295:infection and the start of ATL.
2807:Non-gonococcal urethritis (NGU)
2470:Sexually transmitted infections
2145:CD30+ cutaneous T-cell lymphoma
850:from the original on 2020-02-22
781:from the original on 2012-07-23
769:Matsuoka, M; Suzuki, R (2020).
326:New England Journal of Medicine
3022:Adult T-cell leukemia/lymphoma
3008:Splenic marginal zone lymphoma
2375:Cutaneous lymphoid hyperplasia
2367:Cutaneous lymphoid hyperplasia
2226:Adult T-cell leukemia/lymphoma
2104:Adult T-cell leukemia/lymphoma
2043:Anaplastic large-cell lymphoma
1923:Primary cutaneous immunocytoma
1864:Splenic marginal zone lymphoma
940:British Journal of Haematology
498:Matsuoka, M; Jeang, K (2007).
452:American Journal of Hematology
81:Adult T-cell leukemia/lymphoma
36:Adult T-cell leukemia/lymphoma
1:
2423:Lymphoproliferative disorders
2333:Lymphoproliferative disorders
2283:Extranodal NK-T-cell lymphoma
2155:Lymphomatoid papulosis type A
2134:Lymphomatoid papulosis type B
2048:Lymphomatoid papulosis type A
1908:Diffuse large B-cell lymphoma
1282:10.1016/S0065-230X(03)01003-0
3227:Tropical spastic paraparesis
3132:Lymphocytic choriomeningitis
2539:Mycoplasma hominis infection
2315:Acute biphenotypic leukaemia
2204:Subcutaneous T-cell lymphoma
1215:Journal of Clinical Oncology
1044:10.1182/blood-2009-03-210989
677:Journal of Clinical Oncology
3590:Cytomegalovirus esophagitis
3510:Human parainfluenza viruses
3183:Ramsay Hunt syndrome type 2
2256:Aggressive NK-cell leukemia
2129:Pleomorphic T-cell lymphoma
1835:Lymphomatoid granulomatosis
1130:10.1016/j.imlet.2010.04.003
378:10.1182/blood.V50.3.481.481
338:10.1056/NEJM197403072901018
3876:
3840:Acute lymphocytic leukemia
738:10.1182/blood-2005-04-1730
446:Nicot, Christophe (2005).
3254:Cytomegalovirus retinitis
1509:
993:10.1016/j.soc.2023.01.001
574:10.1007/s11899-018-0458-6
414:10.1007/s12185-011-0957-x
49:
40:
3356:Infectious mononucleosis
3173:Chandipura vesiculovirus
3003:Hepatocellular carcinoma
2948:Nasopharyngeal carcinoma
2881:Hepatocellular carcinoma
2503:lymphogranuloma venereum
2408:Hematological malignancy
2261:Blastic NK cell lymphoma
2089:Granulomatous slack skin
1845:Classic Hodgkin lymphoma
1744:Classic Hodgkin lymphoma
690:10.1200/JCO.2011.37.3472
251:HTLV-1 infection in the
3152:Encephalitis lethargica
2853:viral systemic diseases
2520:Klebsiella granulomatis
123:with no characteristic
95:of the immune system's
3524:Human orthopneumovirus
3178:Herpesviral meningitis
3139:Arbovirus encephalitis
2568:Ureaplasma urealyticum
817:10.1038/sj.onc.1208979
121:non-Hodgkin's lymphoma
3845:Animal viral diseases
2982:Merkel-cell carcinoma
2714:Molluscum contagiosum
2593:Trichomonas vaginalis
2532:Neisseria gonorrhoeae
2508:Chlamydia trachomatis
2287:Angiocentric lymphoma
1877:AIDS-related lymphoma
1701:Splenic marginal zone
869:Tsukasaki, K (2012).
504:Nature Reviews Cancer
18:Adult T-cell lymphoma
3627:Adenovirus infection
3091:Human polyomavirus 2
2920:Oropharyngeal cancer
2674:Human papillomavirus
2563:Ureaplasma infection
2385:with nodular pattern
2084:Pagetoid reticulosis
1696:marginal zone B-cell
1227:10.1200/JCO.18.00501
1084:10.1038/leu.2010.286
50:Human T-cell(normal)
3213:Post-polio syndrome
2849:Infectious diseases
2492:Haemophilus ducreyi
1884:Helicobacter pylori
1711:Nodal marginal zone
1638:Hairy cell leukemia
1504:and related disease
241:brentuximab vedotin
3346:Epstein–Barr virus
3316:Respiratory system
2953:Burkitt's lymphoma
2556:Treponema pallidum
2544:Mycoplasma hominis
2428:Lymphoid leukemias
2348:Leukemoid reaction
2184:Angioimmunoblastic
1850:Burkitt's lymphoma
1441:External resources
1319:(49): 804–6, 812.
1118:Immunology Letters
115:Signs and symptoms
3827:
3826:
3789:
3788:
3540:
3539:
3471:Influenza virus A
3388:Human coronavirus
3278:
3277:
3268:Herpes of the eye
2815:
2814:
2707:HSV-1 & HSV-2
2695:Hepatitis B virus
2436:
2435:
2361:
2360:
2301:
2300:
2235:
2234:
2163:
2162:
2079:Mycosis fungoides
1946:
1945:
1804:
1803:
1748:Nodular sclerosis
1663:follicular B cell
1464:
1463:
1291:978-0-12-006689-6
881:(sup1): s32–s35.
626:(10): 1857–1860.
465:10.1002/ajh.20307
193:blood transfusion
78:
77:
30:Medical condition
16:(Redirected from
3867:
3553:
3548:digestive system
3465:Orthomyxoviridae
3431:SARS coronavirus
3417:MERS coronavirus
3333:
3145:Orthomyxoviridae
3068:
3034:Immune disorders
2958:Hodgkin lymphoma
2934:Kaposi's sarcoma
2842:
2835:
2828:
2819:
2794:
2775:
2756:
2463:
2456:
2449:
2440:
2198:Lennert lymphoma
2064:
1995:
1957:
1822:Primary effusion
1555:
1544:
1511:
1491:
1484:
1477:
1468:
1349:
1328:
1303:
1257:
1256:
1246:
1206:
1200:
1193:
1187:
1186:
1158:
1152:
1151:
1141:
1112:
1106:
1105:
1095:
1063:
1057:
1056:
1046:
1022:
1013:
1012:
972:
966:
965:
955:
931:
925:
924:
898:
866:
860:
859:
857:
855:
835:
829:
828:
800:
791:
790:
788:
786:
766:
760:
759:
749:
732:(13): 4294–302.
717:
711:
710:
692:
668:
662:
661:
651:
611:
602:
601:
553:
544:
543:
495:
486:
485:
467:
443:
434:
433:
397:
391:
390:
380:
356:
350:
349:
321:
187:Transmission of
161:multiple myeloma
157:multiple myeloma
74:
73:
45:
33:
21:
3875:
3874:
3870:
3869:
3868:
3866:
3865:
3864:
3830:
3829:
3828:
3823:
3785:
3765:
3673:
3647:Gastroenteritis
3605:
3602:Gastroenteritis
3596:
3584:Cytomegalovirus
3547:
3536:
3504:Paramyxoviridae
3493:Avian influenza
3369:
3364:Cytomegalovirus
3328:viral pneumonia
3326:
3323:nasopharyngitis
3322:
3319:
3310:
3274:
3248:Cytomegalovirus
3233:
3187:
3075:
3062:
3055:
3028:
2895:Cervical cancer
2855:
2846:
2816:
2811:
2790:
2771:
2752:
2743:
2737:
2681:Genital warts (
2622:
2599:
2574:
2473:
2467:
2437:
2432:
2396:
2357:
2319:
2307:
2297:
2265:
2244:
2231:
2208:
2169:
2159:
2108:
2053:
2001:
1999:
1974:
1969:
1963:
1942:
1894:
1800:
1777:
1765:
1721:
1659:germinal center
1643:
1612:
1574:
1550:
1548:
1528:
1523:
1517:
1505:
1495:
1465:
1460:
1459:
1436:
1435:
1360:
1346:
1306:
1292:
1269:
1266:
1264:Further reading
1261:
1260:
1208:
1207:
1203:
1194:
1190:
1160:
1159:
1155:
1114:
1113:
1109:
1065:
1064:
1060:
1037:(25): 6338–41.
1024:
1023:
1016:
974:
973:
969:
933:
932:
928:
868:
867:
863:
853:
851:
837:
836:
832:
811:(39): 6047–57.
802:
801:
794:
784:
782:
768:
767:
763:
719:
718:
714:
670:
669:
665:
613:
612:
605:
555:
554:
547:
516:10.1038/nrc2111
497:
496:
489:
445:
444:
437:
399:
398:
394:
358:
357:
353:
323:
322:
318:
313:
301:
249:
214:
201:
185:
117:
68:
31:
28:
23:
22:
15:
12:
11:
5:
3873:
3871:
3863:
3862:
3857:
3852:
3847:
3842:
3832:
3831:
3825:
3824:
3822:
3821:
3820:
3819:
3807:
3799:
3797:
3791:
3790:
3787:
3786:
3784:
3783:
3775:
3773:
3767:
3766:
3764:
3763:
3751:
3739:
3727:
3715:
3708:
3702:
3701:
3689:
3683:
3681:
3675:
3674:
3672:
3671:
3664:
3657:
3650:
3638:
3632:
3631:
3630:
3629:
3617:
3611:
3609:
3598:
3597:
3595:
3594:
3593:
3592:
3580:
3579:
3578:
3565:
3563:
3550:
3542:
3541:
3538:
3537:
3535:
3534:
3527:
3520:
3519:
3518:
3498:
3497:
3496:
3495:
3456:
3455:
3454:
3453:
3441:
3440:
3439:
3427:
3426:
3425:
3413:
3412:
3411:
3379:
3377:
3371:
3370:
3368:
3367:
3360:
3359:
3358:
3341:
3339:
3330:
3312:
3311:
3309:
3308:
3307:
3306:
3301:
3288:
3286:
3284:Cardiovascular
3280:
3279:
3276:
3275:
3273:
3272:
3271:
3270:
3258:
3257:
3256:
3243:
3241:
3235:
3234:
3232:
3231:
3230:
3229:
3217:
3216:
3215:
3210:
3197:
3195:
3189:
3188:
3186:
3185:
3180:
3175:
3170:
3169:
3168:
3156:
3155:
3154:
3141:
3136:
3135:
3134:
3122:
3121:
3120:
3108:
3102:
3101:
3100:
3099:
3087:
3081:
3079:
3065:
3063:nervous system
3057:
3056:
3054:
3053:
3052:
3051:
3038:
3036:
3030:
3029:
3027:
3026:
3025:
3024:
3012:
3011:
3010:
3005:
2993:
2987:
2986:
2985:
2984:
2972:
2971:
2970:
2965:
2960:
2955:
2950:
2938:
2937:
2936:
2924:
2923:
2922:
2917:
2915:Vaginal cancer
2912:
2907:
2902:
2897:
2885:
2884:
2883:
2871:
2865:
2863:
2857:
2856:
2847:
2845:
2844:
2837:
2830:
2822:
2813:
2812:
2810:
2809:
2800:
2795:
2787:
2786:
2781:
2776:
2768:
2767:
2762:
2757:
2749:
2747:
2739:
2738:
2736:
2735:
2723:
2711:
2710:
2709:
2702:Herpes simplex
2699:
2687:
2678:
2670:
2669:
2668:
2663:
2658:
2653:
2645:
2632:
2630:
2624:
2623:
2621:
2620:
2615:
2609:
2607:
2601:
2600:
2598:
2597:
2588:Trichomoniasis
2584:
2582:
2576:
2575:
2573:
2572:
2560:
2548:
2536:
2524:
2512:
2496:
2483:
2481:
2475:
2474:
2468:
2466:
2465:
2458:
2451:
2443:
2434:
2433:
2431:
2430:
2425:
2420:
2418:Leukemia cutis
2415:
2410:
2404:
2402:
2398:
2397:
2395:
2394:
2389:
2388:
2387:
2382:
2371:
2369:
2363:
2362:
2359:
2358:
2356:
2355:
2350:
2345:
2339:
2329:
2327:
2321:
2320:
2318:
2317:
2311:
2309:
2303:
2302:
2299:
2298:
2296:
2295:
2290:
2273:
2271:
2267:
2266:
2264:
2263:
2258:
2252:
2250:
2237:
2236:
2233:
2232:
2230:
2229:
2216:
2214:
2210:
2209:
2207:
2206:
2201:
2191:
2186:
2181:
2175:
2173:
2165:
2164:
2161:
2160:
2158:
2157:
2152:
2147:
2137:
2136:
2131:
2126:
2116:
2114:
2110:
2109:
2107:
2106:
2098:Sézary disease
2092:
2091:
2086:
2081:
2072:
2070:
2061:
2055:
2054:
2052:
2051:
2045:
2033:
2032:
2029:Prolymphocytic
2019:
2005:
2003:
1992:
1991:
1990:
1984:
1954:
1948:
1947:
1944:
1943:
1941:
1940:
1935:
1930:
1925:
1920:
1915:
1910:
1904:
1902:
1896:
1895:
1893:
1892:
1880:
1868:
1867:
1866:
1854:
1853:
1852:
1847:
1842:
1837:
1825:
1812:
1810:
1806:
1805:
1802:
1801:
1799:
1798:
1789:
1787:
1767:
1766:
1764:
1763:
1751:
1740:
1738:
1723:
1722:
1720:
1719:
1713:
1708:
1703:
1687:
1686:
1680:
1675:
1670:
1654:
1652:
1645:
1644:
1642:
1641:
1629:
1627:Prolymphocytic
1623:
1621:
1614:
1613:
1611:
1610:
1598:
1585:
1583:
1576:
1575:
1573:
1563:
1561:
1552:
1541:
1540:
1539:
1507:
1506:
1496:
1494:
1493:
1486:
1479:
1471:
1462:
1461:
1458:
1457:
1445:
1444:
1442:
1438:
1437:
1434:
1433:
1422:
1411:
1400:
1381:
1361:
1356:
1355:
1353:
1352:Classification
1345:
1344:External links
1342:
1341:
1340:
1335:
1329:
1304:
1290:
1265:
1262:
1259:
1258:
1221:(8): 677–687.
1201:
1188:
1153:
1107:
1058:
1014:
987:(3): 525–543.
967:
946:(2): 375–382.
926:
861:
830:
792:
761:
712:
683:(8): 837–842.
663:
620:Cancer Science
603:
568:(4): 300–307.
545:
510:(4): 270–280.
487:
435:
392:
351:
315:
314:
312:
309:
300:
297:
248:
245:
213:
210:
200:
197:
184:
181:
131:. Circulating
116:
113:
76:
75:
58:
52:
51:
47:
46:
38:
37:
29:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3872:
3861:
3858:
3856:
3853:
3851:
3848:
3846:
3843:
3841:
3838:
3837:
3835:
3818:
3815:
3814:
3813:
3812:
3808:
3806:
3805:
3801:
3800:
3798:
3796:
3792:
3782:
3781:
3777:
3776:
3774:
3772:
3768:
3761:
3757:
3756:
3752:
3749:
3745:
3744:
3740:
3737:
3733:
3732:
3728:
3725:
3721:
3720:
3716:
3714:
3713:
3709:
3707:
3704:
3703:
3699:
3695:
3694:
3690:
3688:
3685:
3684:
3682:
3680:
3676:
3670:
3669:
3665:
3663:
3662:
3658:
3656:
3655:
3651:
3648:
3644:
3643:
3639:
3637:
3634:
3633:
3628:
3625:
3624:
3623:
3622:
3618:
3616:
3613:
3612:
3610:
3608:
3603:
3599:
3591:
3588:
3587:
3586:
3585:
3581:
3577:
3574:
3573:
3572:
3571:
3567:
3566:
3564:
3562:
3558:
3554:
3551:
3549:
3543:
3533:
3532:
3528:
3526:
3525:
3521:
3517:
3516:Parainfluenza
3514:
3513:
3512:
3511:
3506:
3505:
3500:
3499:
3494:
3490:
3487:
3486:
3485:
3484:
3480:
3476:
3472:
3467:
3466:
3461:
3458:
3457:
3452:
3449:
3448:
3447:
3446:
3442:
3438:
3435:
3434:
3433:
3432:
3428:
3424:
3421:
3420:
3419:
3418:
3414:
3410:
3407:
3406:
3405:
3404:
3400:
3396:
3392:
3389:
3384:
3381:
3380:
3378:
3376:
3372:
3366:
3365:
3361:
3357:
3353:
3352:EBV infection
3350:
3349:
3348:
3347:
3343:
3342:
3340:
3338:
3334:
3331:
3329:
3324:
3317:
3313:
3305:
3302:
3300:
3297:
3296:
3295:
3294:
3290:
3289:
3287:
3285:
3281:
3269:
3266:
3265:
3264:
3263:
3259:
3255:
3252:
3251:
3250:
3249:
3245:
3244:
3242:
3240:
3236:
3228:
3225:
3224:
3223:
3222:
3218:
3214:
3211:
3209:
3208:Poliomyelitis
3206:
3205:
3204:
3203:
3199:
3198:
3196:
3194:
3190:
3184:
3181:
3179:
3176:
3174:
3171:
3167:
3164:
3163:
3162:
3161:
3157:
3153:
3150:
3149:
3147:
3146:
3142:
3140:
3137:
3133:
3130:
3129:
3128:
3127:
3123:
3119:
3116:
3115:
3114:
3113:
3109:
3107:
3104:
3103:
3098:
3095:
3094:
3093:
3092:
3088:
3086:
3083:
3082:
3080:
3078:
3073:
3069:
3066:
3064:
3058:
3050:
3047:
3046:
3045:
3044:
3040:
3039:
3037:
3035:
3031:
3023:
3020:
3019:
3018:
3017:
3013:
3009:
3006:
3004:
3001:
3000:
2999:
2998:
2994:
2992:
2989:
2988:
2983:
2980:
2979:
2978:
2977:
2973:
2969:
2966:
2964:
2961:
2959:
2956:
2954:
2951:
2949:
2946:
2945:
2944:
2943:
2939:
2935:
2932:
2931:
2930:
2929:
2925:
2921:
2918:
2916:
2913:
2911:
2910:Vulvar cancer
2908:
2906:
2905:Penile cancer
2903:
2901:
2898:
2896:
2893:
2892:
2891:
2890:
2886:
2882:
2879:
2878:
2877:
2876:
2872:
2870:
2867:
2866:
2864:
2862:
2858:
2854:
2850:
2843:
2838:
2836:
2831:
2829:
2824:
2823:
2820:
2808:
2804:
2801:
2799:
2796:
2793:
2789:
2788:
2785:
2782:
2780:
2777:
2774:
2770:
2769:
2766:
2763:
2761:
2758:
2755:
2751:
2750:
2748:
2746:
2740:
2733:
2732:
2727:
2724:
2721:
2720:
2715:
2712:
2708:
2705:
2704:
2703:
2700:
2697:
2696:
2691:
2688:
2686:
2684:
2679:
2677:
2675:
2671:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2648:
2646:
2643:
2642:
2637:
2634:
2633:
2631:
2629:
2625:
2619:
2616:
2614:
2611:
2610:
2608:
2606:
2602:
2595:
2594:
2589:
2586:
2585:
2583:
2581:
2577:
2570:
2569:
2564:
2561:
2558:
2557:
2552:
2549:
2546:
2545:
2540:
2537:
2534:
2533:
2528:
2525:
2522:
2521:
2516:
2513:
2510:
2509:
2504:
2500:
2497:
2494:
2493:
2488:
2485:
2484:
2482:
2480:
2476:
2471:
2464:
2459:
2457:
2452:
2450:
2445:
2444:
2441:
2429:
2426:
2424:
2421:
2419:
2416:
2414:
2411:
2409:
2406:
2405:
2403:
2399:
2393:
2390:
2386:
2383:
2381:
2378:
2377:
2376:
2373:
2372:
2370:
2368:
2364:
2354:
2351:
2349:
2346:
2343:
2340:
2338:
2334:
2331:
2330:
2328:
2326:
2325:Lymphocytosis
2322:
2316:
2313:
2312:
2310:
2304:
2294:
2291:
2288:
2284:
2280:
2279:
2275:
2274:
2272:
2268:
2262:
2259:
2257:
2254:
2253:
2251:
2248:
2242:
2238:
2227:
2223:
2222:
2218:
2217:
2215:
2211:
2205:
2202:
2199:
2195:
2192:
2190:
2187:
2185:
2182:
2180:
2179:Hepatosplenic
2177:
2176:
2174:
2172:
2166:
2156:
2153:
2151:
2148:
2146:
2142:
2139:
2138:
2135:
2132:
2130:
2127:
2125:
2121:
2118:
2117:
2115:
2111:
2105:
2102:
2101:
2100:
2099:
2096:
2090:
2087:
2085:
2082:
2080:
2077:
2074:
2073:
2071:
2069:
2065:
2062:
2060:
2056:
2049:
2046:
2044:
2040:
2039:
2035:
2034:
2030:
2026:
2025:
2024:prolymphocyte
2021:
2020:
2017:
2013:
2009:
2006:
2004:
1996:
1993:
1988:
1985:
1983:
1980:
1979:
1978:
1972:
1967:
1962:
1958:
1955:
1953:
1949:
1939:
1936:
1934:
1933:Plasmacytosis
1931:
1929:
1926:
1924:
1921:
1919:
1916:
1914:
1911:
1909:
1906:
1905:
1903:
1901:
1897:
1890:
1889:MALT lymphoma
1886:
1885:
1881:
1878:
1874:
1873:
1869:
1865:
1862:
1861:
1860:
1859:
1855:
1851:
1848:
1846:
1843:
1841:
1838:
1836:
1833:
1832:
1831:
1830:
1826:
1823:
1819:
1818:
1814:
1813:
1811:
1807:
1797:
1796:
1791:
1790:
1788:
1785:
1781:
1776:
1772:
1768:
1761:
1757:
1756:
1752:
1749:
1745:
1742:
1741:
1739:
1736:
1732:
1728:
1724:
1717:
1714:
1712:
1709:
1707:
1704:
1702:
1698:
1697:
1693:
1692:marginal zone
1689:
1688:
1684:
1681:
1679:
1676:
1674:
1671:
1669:
1665:
1664:
1660:
1656:
1655:
1653:
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1646:
1639:
1635:
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1628:
1625:
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1577:
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1564:
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1537:
1534:
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1526:
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1516:
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1508:
1503:
1499:
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1487:
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1478:
1473:
1472:
1469:
1456:
1452:
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1447:
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1443:
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1432:
1428:
1427:
1423:
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1417:
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1406:
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1401:
1399:
1395:
1391:
1390:
1386:
1382:
1380:
1376:
1372:
1371:
1367:
1363:
1362:
1359:
1354:
1350:
1343:
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1330:
1326:
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1318:
1314:
1310:
1305:
1301:
1297:
1293:
1287:
1283:
1279:
1275:
1274:
1268:
1267:
1263:
1254:
1250:
1245:
1240:
1236:
1232:
1228:
1224:
1220:
1216:
1212:
1205:
1202:
1199:
1192:
1189:
1184:
1180:
1176:
1172:
1169:(9): 1293–8.
1168:
1164:
1157:
1154:
1149:
1145:
1140:
1135:
1131:
1127:
1123:
1119:
1111:
1108:
1103:
1099:
1094:
1089:
1085:
1081:
1077:
1073:
1069:
1062:
1059:
1054:
1050:
1045:
1040:
1036:
1032:
1028:
1021:
1019:
1015:
1010:
1006:
1002:
998:
994:
990:
986:
982:
978:
971:
968:
963:
959:
954:
949:
945:
941:
937:
930:
927:
922:
918:
914:
910:
906:
902:
897:
892:
888:
884:
880:
876:
872:
865:
862:
849:
845:
841:
834:
831:
826:
822:
818:
814:
810:
806:
799:
797:
793:
780:
776:
772:
765:
762:
757:
753:
748:
743:
739:
735:
731:
727:
723:
716:
713:
708:
704:
700:
696:
691:
686:
682:
678:
674:
667:
664:
659:
655:
650:
645:
641:
637:
633:
629:
625:
621:
617:
610:
608:
604:
599:
595:
591:
587:
583:
579:
575:
571:
567:
563:
559:
552:
550:
546:
541:
537:
533:
529:
525:
521:
517:
513:
509:
505:
501:
494:
492:
488:
483:
479:
475:
471:
466:
461:
457:
453:
449:
442:
440:
436:
431:
427:
423:
419:
415:
411:
407:
403:
396:
393:
388:
384:
379:
374:
371:(3): 481–92.
370:
366:
362:
355:
352:
347:
343:
339:
335:
332:(10): 572–3.
331:
327:
320:
317:
310:
308:
306:
298:
296:
294:
290:
285:
283:
279:
278:South America
275:
271:
267:
263:
258:
254:
253:United States
246:
244:
242:
237:
235:
234:mogamulizumab
230:
227:
223:
219:
211:
209:
205:
198:
196:
194:
190:
182:
180:
178:
174:
170:
165:
162:
158:
154:
150:
146:
145:hypercalcemia
142:
138:
134:
130:
126:
122:
114:
112:
108:
104:
102:
98:
94:
90:
86:
82:
72:
66:
62:
59:
57:
53:
48:
44:
39:
34:
27:Human disease
19:
3850:Rare cancers
3809:
3802:
3778:
3771:Pancreatitis
3753:
3741:
3729:
3717:
3710:
3691:
3666:
3659:
3652:
3640:
3619:
3582:
3568:
3529:
3522:
3508:
3502:
3469:
3463:
3443:
3429:
3415:
3386:
3362:
3344:
3299:Pericarditis
3291:
3260:
3246:
3219:
3200:
3158:
3143:
3124:
3110:
3089:
3072:Encephalitis
3041:
3021:
3014:
2995:
2974:
2940:
2926:
2887:
2873:
2791:
2779:Epididymitis
2772:
2753:
2745:inflammation
2729:
2717:
2693:
2682:
2673:
2639:
2591:
2566:
2554:
2542:
2530:
2518:
2506:
2490:
2276:
2225:
2219:
2213:By infection
2103:
2094:
2093:
2075:
2036:
2022:
2000:development/
1928:Plasmacytoma
1882:
1870:
1856:
1827:
1815:
1809:By infection
1792:
1753:
1690:
1657:
1631:
1600:
1590:naive B cell
1588:
1549:development/
1448:
1424:
1413:
1402:
1383:
1364:
1316:
1312:
1272:
1218:
1214:
1204:
1191:
1166:
1162:
1156:
1124:(1): 11–18.
1121:
1117:
1110:
1078:(3): 440–8.
1075:
1071:
1061:
1034:
1030:
984:
980:
970:
943:
939:
929:
878:
874:
864:
852:. Retrieved
843:
833:
808:
804:
783:. Retrieved
774:
764:
729:
725:
715:
680:
676:
666:
623:
619:
565:
561:
507:
503:
458:(3): 232–9.
455:
451:
408:(5): 423–8.
405:
401:
395:
368:
364:
354:
329:
325:
319:
305:Pralatrexate
302:
286:
250:
247:Epidemiology
238:
231:
226:Pralatrexate
215:
206:
202:
186:
183:Transmission
169:retroviruses
166:
149:skin lesions
118:
109:
105:
91:) is a rare
88:
84:
80:
79:
3668:Coronavirus
3409:Common cold
3321:acute viral
3304:Myocarditis
3148:(probable)
2900:Anal cancer
2784:Prostatitis
2690:Hepatitis B
2641:HIV-1/HIV-2
2515:Donovanosis
2095:aggressive:
2068:MF+variants
1607:Mantle cell
1602:mantle zone
1139:2433/126715
896:10069/28943
266:New Orleans
133:lymphocytes
3834:Categories
3795:Urogenital
3661:Astrovirus
3621:Adenovirus
3445:SARS-CoV-2
3202:Poliovirus
3077:meningitis
2803:Urethritis
2760:Cervicitis
2731:Zika virus
2726:Zika fever
2613:Crab louse
2171:peripheral
1668:Follicular
1498:Leukaemias
1426:DiseasesDB
875:Hematology
311:References
262:New Jersey
218:zidovudine
153:osteolysis
125:histologic
65:hematology
3706:RNA virus
3687:DNA virus
3679:Hepatitis
3654:Norovirus
3642:Rotavirus
3636:RNA virus
3615:DNA virus
3561:Esophagus
3489:Influenza
3375:RNA virus
3337:DNA virus
3106:RNA virus
3085:DNA virus
2991:RNA virus
2869:DNA virus
2861:Oncovirus
2798:Proctitis
2683:condyloma
2605:Parasitic
2580:Protozoal
2527:Gonorrhea
2499:Chlamydia
2487:Chancroid
2479:Bacterial
2306:Lymphoid+
2076:indolent:
2059:Cutaneous
1900:Cutaneous
1678:GCB DLBCL
1673:Burkitt's
1502:lymphomas
1235:1527-7755
1001:0893-3952
905:1607-8454
699:1527-7755
640:1349-7006
582:1558-822X
524:1474-175X
280:, and in
274:Caribbean
272:, in the
257:serologic
232:In 2021,
224:regimen.
212:Treatment
199:Diagnosis
129:phenotype
56:Specialty
3860:Lymphoma
3804:BK virus
3607:diarrhea
3451:COVID-19
3193:Myelitis
2651:cervical
2551:Syphilis
2413:leukemia
1971:leukemia
1966:lymphoma
1525:leukemia
1520:lymphoma
1450:Orphanet
1300:14587871
1253:30657736
1183:22686619
1148:20398702
1102:21151022
1072:Leukemia
1053:19389878
1009:36925193
962:11380402
921:40003053
913:22507774
848:Archived
825:16155611
805:Oncogene
779:Archived
775:UpToDate
756:16118323
707:22312108
658:22738276
598:51719877
590:30047026
532:17384582
482:30160899
474:15726602
422:22068231
299:Research
220:and the
173:antibody
61:Oncology
3557:Pharynx
3061:Central
2742:General
2647:Cancer
2618:Scabies
2401:General
2308:myeloid
2270:T or NK
2241:NK cell
1595:CLL/SLL
1420:D015459
1409:M9827/3
1325:2891025
1244:6494249
1093:3072512
854:22 July
785:27 July
747:1895233
649:7659271
540:7824653
430:9299403
346:4544052
97:T-cells
3221:HTLV-I
3166:Rabies
3016:HTLV-I
2792:either
2754:female
2661:penile
2656:vulvar
2245:(most
2221:HTLV-1
2113:Non-MF
2002:marker
1975:(most
1961:T cell
1633:CD11c+
1551:marker
1529:(most
1515:B cell
1323:
1298:
1288:
1251:
1241:
1233:
1181:
1146:
1100:
1090:
1051:
1007:
999:
960:
919:
911:
903:
823:
754:
744:
705:
697:
656:
646:
638:
596:
588:
580:
538:
530:
522:
480:
472:
428:
420:
387:301762
385:
344:
293:HTLV-1
289:HTLV-1
282:Africa
189:HTLV-1
141:genome
137:HTLV-1
101:HTLV-1
93:cancer
67:
3817:Mumps
3576:Mumps
3546:Human
2976:MCPyV
2676:(HPV)
2628:Viral
2472:(STI)
2168:Other
2038:CD30+
1784:CD138
1755:CD20+
1649:CD79a
1455:86875
1431:29486
1404:ICD-O
1398:208.9
1394:204.0
1163:Drugs
1031:Blood
917:S2CID
726:Blood
594:S2CID
536:S2CID
478:S2CID
426:S2CID
365:Blood
270:Japan
177:serum
3531:hMPV
3403:OC43
3399:HKU1
3395:NL63
3391:229E
3049:AIDS
2928:KSHV
2773:male
2666:anal
2636:AIDS
2247:CD56
2141:CD30
2120:CD30
2008:TdT+
1952:T/NK
1817:KSHV
1793:see
1780:CD38
1771:PCDs
1735:CD30
1731:CD15
1706:MALT
1618:CD22
1559:TdT+
1536:CD20
1531:CD19
1415:MeSH
1389:9-CM
1321:PMID
1296:PMID
1286:ISBN
1249:PMID
1231:ISSN
1179:PMID
1144:PMID
1098:PMID
1049:PMID
1005:PMID
997:ISSN
958:PMID
909:PMID
901:ISSN
856:2013
844:NCBI
821:PMID
787:2012
752:PMID
703:PMID
695:ISSN
654:PMID
636:ISSN
586:PMID
578:ISSN
528:PMID
520:ISSN
470:PMID
418:PMID
383:PMID
342:PMID
222:CHOP
89:ATLL
3811:MuV
3780:CBV
3755:HEV
3743:HDV
3731:HCV
3719:HAV
3712:CBV
3693:HBV
3570:MuV
3501:V,
3293:CBV
3262:HSV
3239:Eye
3126:LCV
3112:MeV
3043:HIV
2997:HCV
2942:EBV
2889:HPV
2875:HBV
2719:MCV
2278:EBV
2143:+:
2122:-:
2012:ALL
1987:CD8
1982:CD4
1977:CD3
1872:HIV
1858:HCV
1829:EBV
1733:+,
1580:CD5
1566:ALL
1385:ICD
1379:C88
1375:C83
1366:ICD
1278:doi
1239:PMC
1223:doi
1171:doi
1134:hdl
1126:doi
1122:131
1088:PMC
1080:doi
1039:doi
1035:113
989:doi
948:doi
944:113
891:hdl
883:doi
813:doi
742:PMC
734:doi
730:106
685:doi
644:PMC
628:doi
624:103
570:doi
512:doi
460:doi
410:doi
373:doi
334:doi
330:290
87:or
85:ATL
3836::
3507::
3468::
3462:,
3385::
3383:IV
3160:RV
2851:–
2501:,
2010::
1998:By
1786:+)
1782:+/
1775:PP
1737:+)
1727:RS
1547:By
1500:,
1453::
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3722:(
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3698:B
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3483:D
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3479:C
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
