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properties of aminopolycarboxylates can be engineered by varying the groups linking the nitrogen atoms so as to increase selectivity for a particular metal ion. The number of carbon atoms between the nitrogen and carboxyl group can also be varied and substituents can be placed on these carbon atoms.
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when it binds calcium. This reagent provides a means of determining the calcium content in intra-cellular fluid. Details concerning applications of the following examples can be found in the individual articles and/or reference. The aminopolycarboxylate
129:, NTA, which is a tetradentate ligand. These compounds can be described as aminopolycarboxylates. Related ligands can be derived from other amino acids other than glycine, notably
392:"Critical evaluation of stability constants of metal complexes of complexones for biomedical and environmental applications* (IUPAC Technical Report)"
75:
ions. This property makes aminopolycarboxylic acids useful complexone in a wide variety of chemical, medical, and environmental applications.
339:
502:
Curie, C.; Cassin, G.; Couch, D.; Divol, F.; Higuchi, K.; Le Jean, M.; Misson, J.; Schikora, A.; Czernic, P.; Mari, S. (2009).
557:
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504:"Metal movement within the plant: contribution of nicotianamine and yellow stripe 1-like transporters"
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contains two IDA units with the nitrogen atoms linked by two methylene groups and is hexadentate.
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110:, binding the metal centre through the nitrogen and one of two carboxylate oxygen atoms, to form
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bridges linking three nitrogen atoms and is octadentate. TTHA has ten potential donor atoms.
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Replacement of a hydrogen atom on the nitrogen of glycine by another acetate residue, –CH
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Higher density is achieved by linking two or more glycinate or IDA units together.
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is noteworthy as it combines two functionalities: it has high selectivity for
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Anderegg, G.; Arnaud-Neu, F.; Delgado, R.; Felcman, J.; Popov, K. (2005).
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is widespread in plants, where it is used to transport iron.
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is an aminodicarboxylic acid and precursor to other ligands.
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Altogether this allows for a vast range of possibilities.
468:"Critical survey of stability constants of NTA complexes"
185:and it has a substituent which makes the complex
436:Schwarzenbach, G. (1952). "Der Chelateffekt".
140:a metal complex with the iminodiacetate anion
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83:The parent of this family of ligands is the
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63:groups. Aminopolycarboxylates that have
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98:COOH, in which the amino group, NH
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114:complexes of metal ions.
20:a metal complex with the
450:10.1002/hlca.19520350721
55:atoms connected through
41:aminopolycarboxylic acid
485:10.1351/pac198254122693
409:10.1351/pac200577081445
51:containing one or more
43:(sometimes abbreviated
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558:Equilibrium chemistry
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127:nitrilotriacetic acid
59:atoms to two or more
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466:Anderegg, G (1982).
419:20.500.11850/423005
65:lost acidic protons
520:10.1093/aob/mcn207
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123:iminodiacetic acid
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478:(12): 2693–2758.
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49:chemical compound
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563:Chelating agents
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508:Annals of Botany
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444:(7): 2344–2359.
438:Helv. Chim. Acta
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348:Nicotianamine
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192:nicotianamine
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131:aspartic acid
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33:Aspartic acid
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164:Applications
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67:form strong
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514:(1): 1–11.
187:fluorescent
121:COOH gives
552:Categories
366:References
152:has two CH
85:amino acid
230:glycinate
183:magnesium
170:chelating
79:Structure
69:complexes
538:18977764
61:carboxyl
53:nitrogen
529:2707284
179:calcium
112:chelate
88:glycine
47:) is a
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175:Fura-2
108:ligand
57:carbon
353:EDDHA
314:NOTA
310:BAPTA
181:over
73:metal
71:with
24:anion
534:PMID
358:EDDS
318:DOTA
280:EGTA
275:DTPA
270:EDTA
168:The
150:DTPA
146:EDTA
45:APCA
22:EDTA
524:PMC
516:doi
512:103
491:pdf
480:doi
446:doi
425:pdf
414:hdl
404:doi
240:NTA
235:IDA
94:NCH
90:, H
39:An
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374:^
156:CH
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158:2
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