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BAPTA is a component of some fluorescent calcium ion indicators such as
Calcium Green and Oregon Green 488 BAPTA-1 and -2 (OGB-1, OGB2). These indicators change their fluorescence intensity and fluorescence lifetime depending on the calcium ion concentration.
477:
makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions. Due to its properties, it is used in research to chelate
588:
388:
258:
InChI=1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
268:
InChI=1/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
97:
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There is a range of reported values for the dissociation constant of BAPTA, though 0.2 μM appears consistently. The rate constant for calcium binding is 500 μM s.
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541:"The endogenous calcium buffer and the time course of transducer adaptation in auditory hair cells"
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589:"Fluorescent Ca2+ Indicators Excited with Visible Light—Section 19.3"
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Except where otherwise noted, data are given for materials in their
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177 to 179 °C (351 to 354 °F; 450 to 452 K)
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O=C(O)CN(c2ccccc2OCCOc1ccccc1N(CC(=O)O)CC(=O)O)CC(=O)O
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261:Key: FTEDXVNDVHYDQW-UHFFFAOYSA-N
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271:Key: FTEDXVNDVHYDQW-UHFFFAOYAD
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557:10.1523/JNEUROSCI.18-20-08261.1998
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369:(at 25 °C , 100 kPa).
50:2,2′,2′′,2′′′-tetraacetic acid
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593:The Molecular Probes Handbook
545:The Journal of Neuroscience
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468:aminopolycarboxylic acid
470:. The presence of four
339:476.433
46:Preferred IUPAC name
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817:Never to phase III
396:Infobox references
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644:chelation therapy
475:functional groups
404:Chemical compound
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214:CompTox Dashboard
98:Interactive image
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850:Chelating agents
845:Carboxylic acids
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741:Prussian blue
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665:Penicillamine
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693:Deferoxamine
596:. Retrieved
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57:Identifiers
803:from market
721:Dexrazoxane
688:Deferiprone
683:Deferasirox
349:1.494 g/cm
301:Properties
156:100.157.377
118:CHEBI:60888
834:Categories
598:2024-01-22
523:References
466:-specific
460:cetic acid
335:Molar mass
202:K22DDW77C0
129:ChemSpider
85:3D model (
74:85233-19-8
64:CAS Number
813:Phase III
801:Withdrawn
650:, others)
840:Anilines
733:Thallium
501:See also
575:9763471
566:6792854
464:calcium
462:) is a
389:what is
387: (
345:Density
329:
169:PubChem
796:WHO-EM
657:Copper
573:
563:
517:Fura-2
433:ethane
429:henoxy
384:verify
381:
285:SMILES
182:104751
40:Names
17:BAPTA
762:BAPTA
750:Other
648:V03AC
410:(1,2-
408:BAPTA
250:InChI
138:94562
109:ChEBI
87:JSmol
782:EGTA
777:DTPA
772:DMSA
767:DMPS
716:EDTA
703:Lead
675:Iron
571:PMID
512:EGTA
507:EDTA
488:EDTA
486:and
484:EGTA
455:etra
423:mino
193:UNII
757:ALA
711:BAL
561:PMC
553:doi
490:.
414:is(
219:EPA
172:CID
836::
809::
642:/
591:.
569:.
559:.
549:18
547:.
543:.
531:^
480:Ca
449:N′
445:N′
327:10
319:24
315:22
646:(
632:e
625:t
618:v
601:.
577:.
555::
458:a
453:t
451:-
447:,
443:,
441:N
439:,
437:N
435:-
431:)
427:p
421:a
418:-
416:o
412:b
379:N
325:O
323:2
321:N
317:H
313:C
221:)
217:(
89:)
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