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79: 25: 138:. It is reportedly 7-10 times as strong as steel if compared for the same weight, and can stretch up to 20 times its unaltered size without losing its strength properties. It also has very high resistance to extreme temperatures, not losing any of its properties within −20 to 330 degrees Celsius (−4 to 626 degrees Fahrenheit). 224:
Potential applications of artificial spider silk biopolymers include using it for the coating of implants and medical products as well as for artificial ligaments and tendons, due to its elastic tendencies and also since it is a natural product which will synthesize well with the body. Other
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and the milk of recombinant goats, however, no one has been able to produce the silk in commercial quantities thus far. The company was founded in 1993 by Dr. Jeffrey Turner and Paul Ballard and was sold in 2005 to Pharmathene.
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Nexia is the only company that has successfully produced fibers from spider silk expressed in goat's milk. The Lewis lab has produced fibers from recombinant spider silk protein and synthetic spider silk proteins and
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Lazaris, A.; Arcidiacono, S.; Huang, Y.; Zhou, J.; Duguay, F.; Chretien, N.; Welsh, E.; Soares, J.; Karatzas, C. (2002). "Spider Silk Fibers Spun from Soluble Recombinant Silk Produced in Mammalian Cells".
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The purified silk proteins could be dried, dissolved using solvents (DOPE formation) and transformed into microfibers using wet-spinning fiber production methods. The spun fibers were reported to have
217:. He was also able to successfully breed "spider goats" in order to create artificial silk. As of 2012, there are about 30 of the goats at a university-run farm. The 336:
Biopolymer, Volume 8 Polyamides and Complex Proteinaceous Materials II, edited by S.R. Fahnestock & A. Steinbuchel, 2003 Wiley-VCH Verlag, pages 97-117
155:, the golden orb weaver, MaSp1 and MaSp2 When the female goats lactate, the milk, containing the recombinant DNA silk, was to be harvested and subjected to 428: 341: 35: 60: 381: 423: 362: 167: 163: 210: 203: 214: 135: 131: 130:, made by defunct Montreal-based company Nexia Biotechnologies, and later by the Randy Lewis lab of the 352:
Thesis Submitted to the Faculty of Drexel University by Milind Ramesh Gandhi, December 2006, CHAPTER 7
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has plans to turn this silk into a tool for stopping vessels by entangling their propellers.
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potential uses for artificial silk biopolymers include personal care products and textiles.
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Please help update this article to reflect recent events or newly available information.
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Service, R. F. (2002). "MATERIALS SCIENCE: Mammalian Cells Spin a Spidery New Yarn".
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may be in need of reorganization to comply with Knowledge (XXG)'s
127: 213:, a professor formerly at the University of Wyoming and now at 72: 18: 382:"Bridges made of spider silk? You can thank goats for that" 116:
name for a high-strength fiber-based material made of the
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techniques to purify the recombinant silk proteins.
141:The company had created lines of goats to produce 363:"'Spider goats' display angers Ottawa professor" 202:In 2009, two transgenic goats were sold to the 209:Research has since continued with the help of 45:to make improvements to the overall structure. 8: 206:after Nexia Biotechnologies went bankrupt. 123:-like protein extracted from the milk of 61:Learn how and when to remove this message 406:. Utah State University. June 22, 2018. 234: 166:in the range of 2 - 3 grams/denier and 7: 14: 77: 23: 429:Genetically modified organisms 1: 256:10.1126/science.295.5554.419b 194:produced in both recombinant 174:" had been transformed into 445: 384:. Berkeley Science Review 204:Canada Agriculture Museum 170:of 25-45%. The "Biosteel 86:This article needs to be 308:10.1126/science.1065780 424:Biotechnology products 215:Utah State University 136:Utah State University 132:University of Wyoming 369:. CBC. Mar 29, 2012. 300:2002Sci...295..472L 250:(5554): 419b–4421. 43:editing the article 16:Protein-based fiber 342:978-3-527-30223-9 294:(5554): 472–476. 107: 106: 71: 70: 63: 36:layout guidelines 436: 408: 407: 400: 394: 393: 391: 389: 377: 371: 370: 359: 353: 350: 344: 334: 328: 327: 282: 276: 275: 239: 192:genetic chimeras 168:elongation range 152:Nephila clavipes 145:versions of two 102: 99: 93: 81: 80: 73: 66: 59: 55: 52: 46: 27: 26: 19: 444: 443: 439: 438: 437: 435: 434: 433: 414: 413: 412: 411: 402: 401: 397: 387: 385: 379: 378: 374: 367:CBCnews website 361: 360: 356: 351: 347: 335: 331: 284: 283: 279: 241: 240: 236: 231: 184:electrospinning 157:chromatographic 103: 97: 94: 91: 82: 78: 67: 56: 50: 47: 41:Please help by 40: 28: 24: 17: 12: 11: 5: 442: 440: 432: 431: 426: 416: 415: 410: 409: 395: 380:Boatman, Liz. 372: 354: 345: 329: 277: 233: 232: 230: 227: 105: 104: 85: 83: 76: 69: 68: 31: 29: 22: 15: 13: 10: 9: 6: 4: 3: 2: 441: 430: 427: 425: 422: 421: 419: 405: 399: 396: 383: 376: 373: 368: 364: 358: 355: 349: 346: 343: 339: 333: 330: 325: 321: 317: 313: 309: 305: 301: 297: 293: 289: 281: 278: 273: 269: 265: 261: 257: 253: 249: 245: 238: 235: 228: 226: 222: 220: 216: 212: 207: 205: 200: 197: 193: 187: 185: 181: 177: 173: 169: 165: 160: 158: 154: 153: 148: 144: 139: 137: 133: 129: 126: 122: 119: 115: 111: 101: 89: 84: 75: 74: 65: 62: 54: 44: 38: 37: 32:This article 30: 21: 20: 398: 386:. Retrieved 375: 366: 357: 348: 332: 291: 287: 280: 247: 243: 237: 223: 208: 201: 188: 161: 150: 140: 109: 108: 95: 87: 57: 48: 33: 211:Randy Lewis 186:technique. 143:recombinant 121:spider silk 118:recombinant 418:Categories 388:18 October 229:References 182:using the 180:nanomeshes 176:nanofibers 172:biopolymer 164:tenacities 125:transgenic 98:March 2022 219:U.S. Navy 147:spidroins 114:trademark 51:July 2016 316:11799236 272:46425258 264:11799209 110:BioSteel 324:9260156 296:Bibcode 288:Science 244:Science 196:E. coli 88:updated 340:  322:  314:  270:  262:  112:was a 320:S2CID 292:48848 268:S2CID 149:from 128:goats 390:2012 338:ISBN 312:PMID 260:PMID 178:and 134:and 304:doi 252:doi 248:295 420:: 365:. 318:. 310:. 302:. 290:. 266:. 258:. 246:. 392:. 326:. 306:: 298:: 274:. 254:: 100:) 96:( 90:. 64:) 58:( 53:) 49:( 39:.

Index

layout guidelines
editing the article
Learn how and when to remove this message
trademark
recombinant
spider silk
transgenic
goats
University of Wyoming
Utah State University
recombinant
spidroins
Nephila clavipes
chromatographic
tenacities
elongation range
biopolymer
nanofibers
nanomeshes
electrospinning
genetic chimeras
E. coli
Canada Agriculture Museum
Randy Lewis
Utah State University
U.S. Navy
doi
10.1126/science.295.5554.419b
PMID
11799209

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