224:
118:
29:
133:
108:
examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral (arising in one ovary, the other is unaffected). The tumours can vary in size from less than 1 centimetre (0.39 in) to 30 centimetres (12 in). Borderline and malignant
Brenner tumours are
184:
Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, without the characteristic stromal/epithelial pattern of a
Brenner tumour.
533:
223:
637:
370:
Ahr A, Arnold G, Göhring UJ, Costa S, Scharl A, Gauwerky JF (July 1997). "Cytology of ascitic fluid in a patient with metastasizing malignant
Brenner tumor of the ovary. A case report".
1172:
548:
1192:
1315:
172:
The coffee bean nuclei are the nuclear grooves exceptionally pathognomonic to the sex cord stromal tumour, the ovarian granulosa cell tumour, with the fluid-filled spaces
630:
1679:
587:
623:
286:
Green GE, Mortele KJ, Glickman JN, Benson CB (October 2006). "Brenner tumors of the ovary: sonographic and computed tomographic imaging features".
1755:
1664:
1308:
1745:
1636:
498:
1473:
993:
840:
1435:
348:
1674:
1391:
676:
1659:
1760:
1702:
1301:
753:
1803:
1359:
1244:
66:
1798:
1012:
721:
1453:
788:
773:
768:
192:
of the testes and ovarian stromal Leydig cell tumours (ovarian hyperandrogenism and virilization) both have characteristic
886:
793:
1641:
1416:
1187:
1177:
898:
132:
1354:
835:
259:
Marwah N, Mathur SK, Marwah S, Singh S, Karwasra RK, Arora B (April 2005). "Malignant
Brenner tumour--a case report".
205:
1376:
1115:
691:
209:
407:"Rare case of occult testosterone-producing ovarian tumor that was diagnosed by selective venous hormone sampling"
1808:
1239:
1127:
908:
599:
454:
Lamping JD, Blythe JG (September 1977). "Bilateral
Brenner tumors: a case report and review of the literature".
1631:
778:
556:
1723:
1224:
208:(1877–1969), a German surgeon who characterized it in 1907. The term "Brenner tumour" was first used by
1829:
1783:
1669:
1206:
964:
808:
748:
700:
606:
158:
1506:
1042:
893:
850:
845:
173:
1793:
1559:
1463:
1381:
1229:
1074:
798:
726:
1501:
1448:
1219:
1145:
1027:
827:
803:
763:
758:
671:
537:
321:
Caccamo D, Socias M, Truchet C (May 1991). "Malignant
Brenner tumor of the testis and epididymis".
1750:
1626:
1618:
1443:
1411:
1386:
1182:
1157:
1120:
1017:
986:
950:
783:
610:
233:
189:
85:
1545:
1567:
1328:
1282:
1254:
1162:
1022:
813:
646:
567:
494:
471:
436:
387:
356:
330:
303:
268:
117:
45:
37:
615:
1398:
1336:
1111:
1007:
945:
881:
595:
463:
426:
418:
379:
295:
1718:
1697:
1651:
1598:
1537:
1525:
1496:
1483:
1098:
926:
193:
1293:
1234:
1737:
1603:
1581:
1511:
1345:
1259:
1249:
1167:
1152:
1087:
998:
936:
431:
406:
70:
28:
467:
1823:
1775:
1765:
1520:
542:
1491:
1277:
921:
823:
740:
713:
681:
405:
Kuno Y, Baba T, Kuroda T, Teramoto M, Hirokawa N, Endo T, Saito T (October 2018).
237:
147:
125:
561:
1269:
1107:
981:
976:
876:
650:
299:
166:
142:
50:
572:
1608:
1590:
1214:
1063:
229:
196:. The same crystals were also noted under high-power view in Brenner tumours.
162:
121:
89:
1140:
1083:
1032:
154:
105:
78:
440:
307:
272:
525:
391:
334:
92:. Brenner tumours very rarely can occur in other locations, including the
1788:
1689:
1516:
653:
475:
54:
1468:
1458:
736:
709:
657:
422:
383:
972:
872:
864:
93:
74:
1324:
1059:
131:
116:
1297:
619:
236:, the entity Brenner tumours are thought to arise from.
1173:
Multiple cutaneous and uterine leiomyomatosis syndrome
515:
1774:
1736:
1711:
1688:
1650:
1617:
1589:
1580:
1558:
1536:
1482:
1434:
1369:
1353:
1344:
1335:
1268:
1205:
1096:
1072:
1050:
1041:
963:
935:
907:
863:
822:
735:
708:
699:
690:
664:
519:
44:
21:
323:Archives of Pathology & Laboratory Medicine
84:They are most frequently found incidentally on
261:Indian Journal of Pathology & Microbiology
1309:
631:
8:
493:. Carnforth, Lancs: Parthenon. p. 586.
165:) cells with longitudinal nuclear grooves (
1586:
1366:
1350:
1341:
1316:
1302:
1294:
1047:
705:
696:
638:
624:
616:
516:
169:nuclei) lying in abundant fibrous stroma.
27:
18:
491:The history of obstetrics and gynaecology
430:
1756:Clear-cell adenocarcinoma of the vagina
251:
219:
1746:Squamous-cell carcinoma of the vagina
1637:Endometrial intraepithelial neoplasia
353:University of Virginia Medical School
7:
1474:Sex cord tumour with annular tubules
1392:Papillary serous cystadenocarcinoma
677:Desmoplastic small-round-cell tumor
136:High magnification micrograph of a
1660:Cervical intraepithelial neoplasia
1632:Uterine papillary serous carcinoma
14:
1761:Vaginal intraepithelial neoplasia
1703:Gestational trophoblastic disease
754:Aggressive infantile fibromatosis
411:Reproductive Medicine and Biology
288:Journal of Ultrasound in Medicine
67:surface epithelial-stromal tumour
1804:Vulvar intraepithelial neoplasia
1245:Clear-cell sarcoma of the kidney
222:
1013:Intradermal spindle cell lipoma
722:Dermatofibrosarcoma protuberans
65:are an uncommon subtype of the
841:Malignant fibrous histiocytoma
789:Infantile digital fibromatosis
774:Familial myxovascular fibromas
769:Diffuse infantile fibromatosis
489:Philipp EE, O'Dowd MJ (2000).
1:
1680:Villoglandular adenocarcinoma
887:Superficial acral fibromyxoma
794:Juvenile hyaline fibromatosis
468:10.1016/S0046-8177(77)80117-2
176:between the granulosa cells.
1799:Extramammary Paget's disease
1642:Uterine clear-cell carcinoma
1417:Ovarian clear-cell carcinoma
1188:Solitary cutaneous leiomyoma
1178:Multiple cutaneous leiomyoma
899:Ossifying fibromyxoid tumour
294:(10): 1245–51, quiz 1252–4.
109:possible but each are rare.
836:Benign fibrous histiocytoma
300:10.7863/jum.2006.25.10.1245
140:showing the characteristic
1846:
1599:Uterine fibroids/leiomyoma
1454:Sertoli–Leydig cell tumour
1377:Ovarian serous cystadenoma
1116:Embryonal rhabdomyosarcoma
692:Connective tissue neoplasm
36:A Brenner tumor of ovary (
1809:Bartholin gland carcinoma
1751:Botryoid rhabdomyosarcoma
1407:
1240:Malignant rhabdoid tumour
1207:Complex mixed and stromal
1136:
1128:Alveolar rhabdomyosarcoma
35:
26:
1436:Sex cord–gonadal stromal
1355:Glandular and epithelial
779:Fibroma of tendon sheath
809:Oral submucous fibrosis
749:Aggressive fibromatosis
665:Not otherwise specified
159:transitional epithelial
1507:Endodermal sinus tumor
851:Solitary fibrous tumor
846:Atypical fibroxanthoma
378:(4 Suppl): 1299–1304.
151:
129:
1794:Papillary hidradenoma
1724:Mixed MĂĽllerian tumor
1675:Glassy-cell carcinoma
1464:Granulosa cell tumour
1225:Mixed MĂĽllerian tumor
157:, there are nests of
135:
124:of a Brenner tumour.
120:
1665:Clear-cell carcinoma
1382:Mucinous cystadenoma
1230:Mesoblastic nephroma
799:Plantar fibromatosis
727:Desmoplastic fibroma
1502:Embryonal carcinoma
1449:Sertoli cell tumour
1360:surface epithelial-
1220:Pleomorphic adenoma
1028:Spindle cell lipoma
828:histiocytic sarcoma
804:Pleomorphic fibroma
764:Collagenous fibroma
759:Aponeurotic fibroma
672:Soft-tissue sarcoma
359:on 4 February 2006.
190:Leydig cell tumours
73:. The majority are
1627:Endometrioid tumor
1444:Leydig cell tumour
1412:Endometrioid tumor
1387:Cystadenocarcinoma
1183:Neural fibrolipoma
1158:Angiolipoleiomyoma
1121:Sarcoma botryoides
1018:Pleomorphic lipoma
987:Myxoid liposarcoma
951:Clear-cell sarcoma
784:Fibromatosis colli
611:University of Utah
423:10.1002/rmb2.12213
349:"Pathology Thread"
234:Walthard cell nest
180:Similar conditions
152:
130:
86:pelvic examination
77:, but some can be
1817:
1816:
1732:
1731:
1576:
1575:
1568:Adenomatoid tumor
1554:
1553:
1430:
1429:
1329:urogenital system
1291:
1290:
1283:Adenomatoid tumor
1255:Pancreatoblastoma
1201:
1200:
1163:Genital leiomyoma
1023:Lipoblastomatosis
959:
958:
859:
858:
814:Pachydermodactyly
582:
581:
500:978-1-85070-040-1
384:10.1159/000333524
216:Additional images
174:Call–Exner bodies
71:ovarian neoplasms
60:
59:
16:Medical condition
1837:
1587:
1497:Nongerminomatous
1399:Krukenberg tumor
1367:
1351:
1342:
1318:
1311:
1304:
1295:
1112:rhabdomyosarcoma
1101:
1077:
1053:
1048:
1008:Chondroid lipoma
946:Synovial sarcoma
882:Cutaneous myxoma
706:
697:
640:
633:
626:
617:
603:
598:. Archived from
588:"Brenner tumour"
517:
505:
504:
486:
480:
479:
451:
445:
444:
434:
402:
396:
395:
367:
361:
360:
355:. Archived from
345:
339:
338:
318:
312:
311:
283:
277:
276:
256:
226:
204:It is named for
188:Histologically,
31:
19:
1845:
1844:
1840:
1839:
1838:
1836:
1835:
1834:
1820:
1819:
1818:
1813:
1770:
1728:
1719:Uterine sarcoma
1707:
1698:Choriocarcinoma
1684:
1646:
1613:
1572:
1550:
1546:Meigs' syndrome
1532:
1526:Choriocarcinoma
1478:
1426:
1403:
1361:
1358:
1331:
1322:
1292:
1287:
1264:
1197:
1132:
1099:Skeletal muscle
1097:
1092:
1073:
1068:
1051:
1037:
955:
931:
927:Phyllodes tumor
909:Fibroepithelial
903:
855:
818:
731:
686:
660:
644:
586:
583:
578:
577:
528:
514:
509:
508:
501:
488:
487:
483:
456:Human Pathology
453:
452:
448:
404:
403:
399:
372:Acta Cytologica
369:
368:
364:
347:
346:
342:
320:
319:
315:
285:
284:
280:
258:
257:
253:
248:
241:
227:
218:
202:
194:Reinke crystals
182:
115:
102:
63:Brenner tumours
17:
12:
11:
5:
1843:
1841:
1833:
1832:
1830:Ovarian cancer
1822:
1821:
1815:
1814:
1812:
1811:
1806:
1801:
1796:
1791:
1786:
1780:
1778:
1772:
1771:
1769:
1768:
1763:
1758:
1753:
1748:
1742:
1740:
1734:
1733:
1730:
1729:
1727:
1726:
1721:
1715:
1713:
1709:
1708:
1706:
1705:
1700:
1694:
1692:
1686:
1685:
1683:
1682:
1677:
1672:
1667:
1662:
1656:
1654:
1648:
1647:
1645:
1644:
1639:
1634:
1629:
1623:
1621:
1615:
1614:
1612:
1611:
1606:
1604:Leiomyosarcoma
1601:
1595:
1593:
1584:
1578:
1577:
1574:
1573:
1571:
1570:
1564:
1562:
1560:Fallopian tube
1556:
1555:
1552:
1551:
1549:
1548:
1542:
1540:
1534:
1533:
1531:
1530:
1529:
1528:
1523:
1514:
1512:Gonadoblastoma
1509:
1504:
1494:
1488:
1486:
1480:
1479:
1477:
1476:
1471:
1466:
1461:
1456:
1451:
1446:
1440:
1438:
1432:
1431:
1428:
1427:
1425:
1424:
1422:Brenner tumour
1419:
1414:
1408:
1405:
1404:
1402:
1401:
1396:
1395:
1394:
1384:
1379:
1373:
1371:
1364:
1348:
1339:
1333:
1332:
1327:of the female
1323:
1321:
1320:
1313:
1306:
1298:
1289:
1288:
1286:
1285:
1280:
1274:
1272:
1266:
1265:
1263:
1262:
1260:Carcinosarcoma
1257:
1252:
1250:Hepatoblastoma
1247:
1242:
1237:
1232:
1227:
1222:
1217:
1211:
1209:
1203:
1202:
1199:
1198:
1196:
1195:
1190:
1185:
1180:
1175:
1170:
1168:Leiomyosarcoma
1165:
1160:
1155:
1153:Angioleiomyoma
1150:
1149:
1148:
1137:
1134:
1133:
1131:
1130:
1125:
1124:
1123:
1104:
1102:
1094:
1093:
1091:
1090:
1088:leiomyosarcoma
1080:
1078:
1070:
1069:
1067:
1066:
1056:
1054:
1045:
1039:
1038:
1036:
1035:
1030:
1025:
1020:
1015:
1010:
1004:
1003:
1002:
1001:
999:Angiomyolipoma
991:
990:
989:
984:
969:
967:
961:
960:
957:
956:
954:
953:
948:
942:
940:
933:
932:
930:
929:
924:
919:
917:Brenner tumour
913:
911:
905:
904:
902:
901:
896:
891:
890:
889:
884:
869:
867:
861:
860:
857:
856:
854:
853:
848:
843:
838:
832:
830:
820:
819:
817:
816:
811:
806:
801:
796:
791:
786:
781:
776:
771:
766:
761:
756:
751:
745:
743:
733:
732:
730:
729:
724:
718:
716:
703:
694:
688:
687:
685:
684:
679:
674:
668:
666:
662:
661:
645:
643:
642:
635:
628:
620:
614:
613:
604:
602:on 2012-02-05.
592:Medcyclopaedia
580:
579:
576:
575:
564:
553:
545:
529:
524:
523:
521:
520:Classification
513:
512:External links
510:
507:
506:
499:
481:
462:(5): 583–585.
446:
417:(4): 504–508.
397:
362:
340:
329:(5): 524–527.
313:
278:
267:(2): 251–252.
250:
249:
247:
244:
243:
242:
228:
221:
217:
214:
201:
198:
181:
178:
155:Histologically
138:Brenner tumour
114:
111:
101:
98:
58:
57:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1842:
1831:
1828:
1827:
1825:
1810:
1807:
1805:
1802:
1800:
1797:
1795:
1792:
1790:
1787:
1785:
1782:
1781:
1779:
1777:
1773:
1767:
1766:Vaginal cysts
1764:
1762:
1759:
1757:
1754:
1752:
1749:
1747:
1744:
1743:
1741:
1739:
1735:
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1717:
1716:
1714:
1710:
1704:
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1622:
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1616:
1610:
1607:
1605:
1602:
1600:
1597:
1596:
1594:
1592:
1588:
1585:
1583:
1579:
1569:
1566:
1565:
1563:
1561:
1557:
1547:
1544:
1543:
1541:
1539:
1535:
1527:
1524:
1522:
1521:Struma ovarii
1518:
1515:
1513:
1510:
1508:
1505:
1503:
1500:
1499:
1498:
1495:
1493:
1490:
1489:
1487:
1485:
1481:
1475:
1472:
1470:
1467:
1465:
1462:
1460:
1457:
1455:
1452:
1450:
1447:
1445:
1442:
1441:
1439:
1437:
1433:
1423:
1420:
1418:
1415:
1413:
1410:
1409:
1406:
1400:
1397:
1393:
1390:
1389:
1388:
1385:
1383:
1380:
1378:
1375:
1374:
1372:
1368:
1365:
1363:
1362:stromal tumor
1356:
1352:
1349:
1347:
1343:
1340:
1338:
1334:
1330:
1326:
1319:
1314:
1312:
1307:
1305:
1300:
1299:
1296:
1284:
1281:
1279:
1276:
1275:
1273:
1271:
1267:
1261:
1258:
1256:
1253:
1251:
1248:
1246:
1243:
1241:
1238:
1236:
1233:
1231:
1228:
1226:
1223:
1221:
1218:
1216:
1213:
1212:
1210:
1208:
1204:
1194:
1191:
1189:
1186:
1184:
1181:
1179:
1176:
1174:
1171:
1169:
1166:
1164:
1161:
1159:
1156:
1154:
1151:
1147:
1144:
1143:
1142:
1139:
1138:
1135:
1129:
1126:
1122:
1119:
1118:
1117:
1113:
1109:
1106:
1105:
1103:
1100:
1095:
1089:
1085:
1082:
1081:
1079:
1076:
1075:Smooth muscle
1071:
1065:
1061:
1058:
1057:
1055:
1049:
1046:
1044:
1040:
1034:
1031:
1029:
1026:
1024:
1021:
1019:
1016:
1014:
1011:
1009:
1006:
1005:
1000:
997:
996:
995:
992:
988:
985:
983:
980:
979:
978:
974:
971:
970:
968:
966:
962:
952:
949:
947:
944:
943:
941:
938:
934:
928:
925:
923:
920:
918:
915:
914:
912:
910:
906:
900:
897:
895:
892:
888:
885:
883:
880:
879:
878:
874:
871:
870:
868:
866:
862:
852:
849:
847:
844:
842:
839:
837:
834:
833:
831:
829:
825:
821:
815:
812:
810:
807:
805:
802:
800:
797:
795:
792:
790:
787:
785:
782:
780:
777:
775:
772:
770:
767:
765:
762:
760:
757:
755:
752:
750:
747:
746:
744:
742:
738:
734:
728:
725:
723:
720:
719:
717:
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206:Fritz Brenner
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22:Brenner tumor
20:
1492:Dysgerminoma
1421:
1278:Mesothelioma
1235:Wilms' tumor
922:Fibroadenoma
916:
824:Histiocytoma
741:fibromatosis
714:fibrosarcoma
682:Skin sarcoma
600:the original
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357:the original
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210:Robert Meyer
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106:pathological
103:
100:Presentation
83:
62:
61:
1619:Endometrium
1270:Mesothelial
1108:Rhabdomyoma
982:Myelolipoma
977:liposarcoma
894:Angiomyxoma
877:myxosarcoma
701:Fibromatous
651:soft tissue
212:, in 1932.
167:coffee bean
143:coffee bean
51:Gynaecology
1609:Adenomyoma
1591:Myometrium
1215:Adenomyoma
1064:myosarcoma
965:Lipomatous
865:Myxomatous
647:Connective
568:DiseasesDB
246:References
230:Micrograph
163:urothelial
122:Micrograph
90:laparotomy
1484:Germ cell
1146:Cutaneous
1141:Leiomyoma
1084:Leiomyoma
1043:Myomatous
1033:Hibernoma
607:Histology
113:Diagnosis
104:On gross
79:malignant
69:group of
46:Specialty
1824:Category
1789:Melanoma
1690:Placenta
1517:Teratoma
937:Synovial
658:sarcomas
441:30377407
308:16998096
273:16758686
146:nuclei.
55:oncology
1712:General
1538:Fibroma
1469:Luteoma
1459:Thecoma
1346:Ovaries
1052:General
737:Fibroma
710:Fibroma
562:D001948
432:6194242
392:9990262
335:2021324
40:image).
1738:Vagina
1652:Cervix
1582:Uterus
1337:Adnexa
1325:Tumors
994:PEComa
973:Lipoma
873:Myxoma
654:tumors
552:: 9000
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476:903146
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200:Eponym
94:testes
88:or at
75:benign
1776:Vulva
1193:STUMP
1060:Myoma
939:-like
573:33431
549:ICD-O
232:of a
38:gross
1370:CMS:
656:and
557:MeSH
538:9-CM
495:ISBN
472:PMID
437:PMID
388:PMID
331:PMID
304:PMID
269:PMID
1784:SCC
1670:SCC
609:at
543:220
534:ICD
464:doi
427:PMC
419:doi
380:doi
327:115
296:doi
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