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of myeloma cast nephropathy. Myelomatous casts are PAS negative (left of image). Hyaline casts are PAS positive (right of image).
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Myeloma cast nephropathy is considered to be a medical emergency because if untreated, it leads to irreversible kidney failure.
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In myeloma cast nephropathy, filtered Îș or λ light chains that bind to
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and low fluid intake contribute to the development of casts.
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It is diagnosed by histological examination of kidney
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Pocket
Companion to Brenner and Rector's The Kidney
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