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Verrucous carcinoma

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210: 198: 73: 46: 240:, but display a blunt papillary/pebbly surface and keratin-filled crypts extending deep into the connective tissue. These keratin-filled crypts resemble rabbit burrows. It is located almost exclusively on the foot, but at least 50 oral locations have also been observed. 179:. The oral cavity is the most common site of this tumor. The ages range from 50 to 80 years with a male predominance and a median age of 67 years. VC may grow large in size, resulting in the destruction of adjacent tissue, such as bone and cartilage. 209: 197: 151:
This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer". Chewing betel nuts is an additional risk factor commonly seen in Taiwan.
664:- "This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited." 406:
Yeudall WA, Torrance LK, Elsegood KA, Speight P, Scully C, Prime SS (January 1993). "Ras gene point mutation is a rare event in premalignant tissues and malignant cells and tissues from oral mucosal lesions".
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to distant parts of the body is rare. Patients with oral verrucous carcinoma may be at greater risk of a second oral squamous cell carcinoma, for which the prognosis is worse.
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Kuo MY, Jeng JH, Chiang CP, Hahn LJ (February 1994). "Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan".
164:, while betel nut is an additional factor in Taiwan. Different gene mutation sites in head and neck cancer between western countries and Taiwan have been reported. 1952: 928: 3562: 2910: 1564: 3537: 2735: 2686: 251:
Surgical excision alone is effective for controlling VC, but elective neck dissection is not necessary even in patients in the advanced stages.
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Surgery is considered the treatment of choice, but the extent of surgical margin and the adjuvant radiotherapy are still controversial.
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Medina JE, Dichtel W, Luna MA (July 1984). "Verrucous-squamous carcinomas of the oral cavity. A clinicopathologic study of 104 cases".
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Surgeons must provide adequate specimens including the full thickness of the tumors and adjacent uninvolved mucosa for correct
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High magnification. There is prominent acanthosis. The tumor front is broad-based and pushes the subepithelial tissues.
3162: 3125: 2855: 2136: 2048: 1442: 1359: 992: 298: 236:) is a subtype of verrucous carcinoma, characterized by well-differentiated epithelial cells which lack cytological 3172: 3120: 2927: 2860: 2629: 2129: 2124: 2075: 1499: 1481: 1391: 1342: 203:
Low-magnification micrograph of penile verrucous carcinoma. The tumor is characterized by prominent papillomatosis.
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Kang CJ, Chang JT, Chen TM, Chen IH, Liao CT (November 2003). "Surgical treatment of oral verrucous carcinoma".
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Most patients with verrucous carcinoma have a good prognosis. Local recurrence is not uncommon, but
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Xu J, Gimenez-Conti IB, Cunningham JE, Collet AM, Luna MA, Lanfranchi HE, et al. (July 1998).
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Verrucous carcinoma may occur in various head and neck locations, as well as in the genitalia or
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It can rapidly become fixed with underlying periosteum and cause gradual destruction of jaw bone.
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The presentation of VC originated from exposure to different carcinogens may not be the same.
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Saranath D, Chang SE, Bhoite LT, Panchal RG, Kerr IB, Mehta AR, et al. (April 1991).
113: 94: 1198: 490: 730:"An unusual case of bilateral verrucous carcinoma of the foot (epithelioma cuniculatum)" 583:
McDonald JS, Crissman JD, Gluckman JL (1982). "Verrucous carcinoma of the oral cavity".
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It is a slow growing, diffuse, exophytic lesion usually covered by leukoplakic patches.
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Koch BB, Trask DK, Hoffman HT, Karnell LH, Robinson RA, Zhen W, Menck HR (July 2001).
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orally, so much so that it is sometimes referred to as "Snuff dipper's cancer".
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Lesion shows painful multiple rugae-like folds and deep clefts between them.
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10.1002/(sici)1097-0142(19980715)83:2<204::aid-cncr2>3.0.co;2-q
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10.1002/1097-0142(20010701)92:1<110::aid-cncr1298>3.0.co;2-k
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Philippou P, Kitsios C, Miliatou M, Poullou C, Konstantinou P (2019).
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Ridge JA, Glisson BS, Lango MN, Feigenberg S, Horwitz EM (2008).
3511: 3410: 3334: 3092: 2971: 2757: 2547: 2185: 1848: 1788: 1676: 1584: 1546: 910: 1586: 301:. In Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (eds.). 89:. This form of cancer is often seen in those who chew 839: 723: 721: 1517: 1490: 1467: 1428: 1417: 1381: 1333: 1310: 1299: 1264: 1207: 1170: 1142: 1061: 1047: 1038: 1006: 954: 945: 880: 843: 676:
Andrews' Diseases of the Skin: Clinical Dermatology
60: 38: 2986:Jaw joints, chewing muscles and bite abnormalities 728:Suen K, Wijeratne S, Patrikios J (December 2012). 160:The major risk factors are cigarette smoking and 616: 614: 3341:Teeth, jaws, tongue and associated soft tissues 303:Cancer Management: A Multidisciplinary Approach 1953:Hereditary benign intraepithelial dyskeratosis 112:Site – gingiva, buccal mucosa, 106:Age – usually over 60 years old 2911:Neuralgia-inducing cavitational osteonecrosis 1558: 922: 8: 777: 775: 773: 788:Journal of Clinical and Diagnostic Research 700:Rapini RP, Bolognia JL, Jorizzo JL (2007). 510: 508: 3508: 3407: 3331: 3089: 2968: 2754: 2544: 2182: 1845: 1785: 1673: 1581: 1565: 1551: 1543: 1425: 1307: 1058: 1044: 951: 929: 915: 907: 840: 71: 44: 35: 807: 782:Datar UV, Kale A, Mane D (January 2017). 753: 648: 638: 559: 382: 333: 137:Regional lymph nodes tender and enlarged. 109:Sex – males are more prone 444:Journal of Oral Pathology & Medicine 3538:Oral manifestations of systemic disease 2687:Acute necrotizing ulcerative gingivitis 289: 193: 2724:As a manifestation of systemic disease 125:Invasive lesions quickly invade bones. 7: 3563:Epidermal nevi, neoplasms, and cysts 2570:Gums and tooth-supporting structures 674:James W, Berger T, Elston D (2005). 491:10.1001/archotol.1984.00800330019003 278:List of verrucous carcinoma subtypes 29:List of verrucous carcinoma subtypes 3221:Papillary cystadenoma lymphomatosum 3064:Temporomandibular joint dysfunction 1404:Papillary serous cystadenocarcinoma 140:Pain and difficulty in mastication. 2338:Maxillary lateral incisor agenesis 1822:Inflammatory papillary hyperplasia 973:Combined small-cell lung carcinoma 456:10.1111/j.1600-0714.1994.tb00259.x 409:European Journal of Cancer, Part B 25: 3440:Cutaneous sinus of dental origin 3377:Obesity hypoventilation syndrome 3372:Central hypoventilation syndrome 3254:Carcinoma ex pleomorphic adenoma 2682:Necrotizing periodontal diseases 2662:Hereditary gingival fibromatosis 1574:Oral and maxillofacial pathology 734:Journal of Surgical Case Reports 208: 196: 3286:Chronic sclerosing sialadenitis 2923:Osteoporotic bone marrow defect 2377:Keratocystic odontogenic tumour 1291:Syringocystadenoma papilliferum 85:(VC) is an uncommon variant of 3271:Sclerosing polycystic adenosis 3106:Benign lymphoepithelial lesion 1079:Familial adenomatous polyposis 131:Enlarged regional lymph nodes. 1: 3465:Melkersson–Rosenthal syndrome 3414:Soft tissues around the mouth 3111:Ectopic salivary gland tissue 1454:Paget's disease of the breast 1396:Pancreatic serous cystadenoma 2635:Gingival cyst of the newborn 2244:Failure of eruption of teeth 1948:Hand, foot and mouth disease 1933:Focal epithelial hyperplasia 1871:Angina bullosa haemorrhagica 1817:Palatal cysts of the newborn 1740:Transient lingual papillitis 1458:Extramammary Paget's disease 1185:Multiple endocrine neoplasia 800:10.7860/JCDR/2017/23437.9226 421:10.1016/0964-1955(93)90012-4 273:List of cutaneous conditions 3163:Salivary gland diverticulum 3126:Necrotizing sialometaplasia 2137:Smokeless tobacco keratosis 2049:Basaloid squamous carcinoma 1443:Pancreatic ductal carcinoma 1360:Mucinous cystadenocarcinoma 993:Transitional cell carcinoma 678:(10th ed.). Saunders. 53:Verrucous carcinoma on the 3594: 3173:Salivary gland hyperplasia 3121:HIV salivary gland disease 2630:Gingival cyst of the adult 2076:Oral florid papillomatosis 1500:Medullary breast carcinoma 1482:Invasive lobular carcinoma 1392:Ovarian serous cystadenoma 1343:Signet ring cell carcinoma 517:Chang Gung Medical Journal 479:Archives of Otolaryngology 26: 3518: 3507: 3420: 3412:Orofacial soft tissues – 3406: 3347: 3330: 3178:Salivary gland hypoplasia 3101: 3088: 2992: 2967: 2906:Bisphosphonate-associated 2800:Idiopathic osteosclerosis 2775: 2753: 2576: 2543: 2271:Dentinogenesis imperfecta 2207: 2181: 1861: 1844: 1797: 1784: 1735:Median rhomboid glossitis 1685: 1672: 1593: 1580: 1477:Lobular carcinoma in situ 1400:Serous cystadenocarcinoma 1237:Clear-cell adenocarcinoma 1026:Bartholin gland carcinoma 937:Glandular and epithelial 702:Dermatology: 2-Volume Set 363:British Journal of Cancer 52: 43: 3485:Orofacial granulomatosis 3264:Mucoepidermoid carcinoma 3249:Adenoid cystic carcinoma 3183:Salivary gland neoplasms 2974:Temporomandibular joints 2945:Periapical periodontitis 2677:Linear gingival erythema 2445:Regional odontodysplasia 2291:Enamel hypocalcification 1505:Medullary thyroid cancer 1438:Mammary ductal carcinoma 1373:Mucoepidermoid carcinoma 1227:Adenoid cystic carcinoma 1194:Adrenocortical carcinoma 1134:Hepatocellular carcinoma 3382:Obstructive sleep apnea 3148:Salivary duct stricture 2928:Paget's disease of bone 2425:Pulp canal obliteration 2266:Dentin hypersensitivity 2212:Amelogenesis imperfecta 2064:Squamous cell carcinoma 2044:Adenosquamous carcinoma 2031:Squamous cell papilloma 2008:Melanocytic oral lesion 983:Squamous-cell carcinoma 627:Case Reports in Urology 585:Head & Neck Surgery 226:Epithelioma cuniculatum 119:Clinical presentation: 87:squamous cell carcinoma 3573:Oral mucosal pathology 3528:Hemifacial hypertrophy 3495:Pyostomatitis vegetans 3168:Salivary gland fistula 3158:Salivary gland atresia 3153:Salivary gland aplasia 3007:Mandibular dislocation 2978:muscles of mastication 2856:Calcifying odontogenic 2485:Vertical root fracture 2480:Cracked tooth syndrome 2455:Shovel-shaped incisors 2350:Wisdom tooth impaction 2232:Early childhood caries 2098:Benign mucous membrane 2059:Spindle cell carcinoma 1968:Intraoral dental sinus 1886:Burning mouth syndrome 1366:Pseudomyxoma peritonei 1190:Adrenocortical adenoma 1130:Hepatocellular adenoma 597:10.1002/hed.2890050106 299:"Head and Neck Tumors" 3337:Stomatognathic system 3239:Acinic cell carcinoma 2861:Glandular odontogenic 2013:Molluscum contagiosum 1528:Acinic cell carcinoma 1252:Papillary hidradenoma 835:eMedicine.com article 230:Carcinoma cuniculatum 18:Carcinoma cuniculatum 3480:Oral Crohn's disease 3435:Basal cell carcinoma 3074:Condylar hyperplasia 3059:Maxillary hypoplasia 2625:Gingival enlargement 2558:periodontal ligament 2164:Verruciform xanthoma 1896:Condyloma acuminatum 1356:Mucinous cystadenoma 1215:Neuroendocrine tumor 1152:Renal cell carcinoma 988:Basal-cell carcinoma 968:Small-cell carcinoma 704:. St. Louis: Mosby. 640:10.1155/2019/1537379 375:10.1038/bjc.1991.133 3490:Perioral dermatitis 3226:Pleomorphic adenoma 3206:Monomorphic adenoma 3196:Canalicular adenoma 3069:Condylar hypoplasia 3002:Condylar resorption 2846:Lateral periodontal 2805:Mandibular fracture 2704:Periodontal abscess 2301:Turner's hypoplasia 2069:Verrucous carcinoma 2018:Morsicatio buccarum 1998:Lupus erythematosus 1911:Erythema multiforme 1827:Stomatitis nicotina 1492:Medullary carcinoma 978:Verrucous carcinoma 746:10.1093/jscr/rjs020 162:alcohol consumption 83:Verrucous carcinoma 39:Verrucous carcinoma 3533:Facial hemiatrophy 3387:Periodic breathing 3318:Sjögren's syndrome 3191:Basal cell adenoma 2955:Torus mandibularis 2933:Periapical abscess 2916:Osteoradionecrosis 2841:Buccal bifurcation 2820:Intraosseous cysts 2709:Periodontal trauma 2613:Pyogenic granuloma 2460:Supernumerary root 2413:Pulp calcification 2401:Premature eruption 2372:Odontogenic tumors 2169:White sponge nevus 2142:Submucous fibrosis 2086:Smoker's melanosis 1973:Irritation fibroma 1812:High-arched palate 1720:Foliate papillitis 1710:Cunnilingus tongue 1695:Black hairy tongue 1625:Congenital lip pit 1325:Cystadenocarcinoma 1157:Endometrioid tumor 1120:Cholangiocarcinoma 1008:Complex epithelial 998:Inverted papilloma 881:External resources 101:Signs and symptoms 3550: 3549: 3546: 3545: 3503: 3502: 3402: 3401: 3326: 3325: 3231:Sebaceous adenoma 3084: 3083: 2963: 2962: 2874:Median mandibular 2869:Nasopalatine duct 2785:Alveolar osteitis 2749: 2748: 2736:Perio-endo lesion 2618:Congenital epulis 2539: 2538: 2296:Enamel hypoplasia 2177: 2176: 2152:Riga–Fede disease 2003:Melanocytic nevus 1943:Hairy leukoplakia 1906:Epulis fissuratum 1840: 1839: 1780: 1779: 1730:Geographic tongue 1668: 1667: 1540: 1539: 1536: 1535: 1513: 1512: 1469:Lobular carcinoma 1413: 1412: 1260: 1259: 1034: 1033: 904: 903: 711:978-1-4160-2999-1 80: 79: 33:Medical condition 16:(Redirected from 3585: 3509: 3408: 3332: 3201:Ductal papilloma 3090: 2969: 2866:Non-odontogenic: 2851:Globulomaxillary 2790:Buccal exostosis 2755: 2699:Peri-implantitis 2545: 2261:Dentin dysplasia 2183: 2159:Verruca vulgaris 2054:Mucosal melanoma 1901:Darier's disease 1876:Behçet's disease 1846: 1802:Bednar's aphthae 1786: 1674: 1660:Trumpeter's wart 1582: 1567: 1560: 1553: 1544: 1460: 1430:Ductal carcinoma 1426: 1406: 1362: 1348:Krukenberg tumor 1308: 1162:Renal oncocytoma 1074:Linitis plastica 1063:Gastrointestinal 1059: 1045: 952: 931: 924: 917: 908: 841: 822: 821: 811: 794:(1): ZD37–ZD39. 779: 768: 767: 757: 725: 716: 715: 697: 691: 689: 671: 665: 662: 652: 642: 618: 609: 608: 580: 574: 573: 563: 539: 533: 532: 512: 503: 502: 474: 468: 467: 439: 433: 432: 403: 397: 396: 386: 354: 348: 347: 337: 313: 307: 306: 305:(11th ed.). 294: 212: 200: 177:sole of the foot 76: 75: 48: 36: 21: 3593: 3592: 3588: 3587: 3586: 3584: 3583: 3582: 3553: 3552: 3551: 3542: 3514: 3499: 3455:Ludwig's angina 3416: 3398: 3357:Mouth breathing 3343: 3322: 3143:Pneumoparotitis 3116:Frey's syndrome 3097: 3095:Salivary glands 3080: 2988: 2959: 2938:Phoenix abscess 2771: 2767:hard tissues – 2745: 2667:Hypercementosis 2586:Cementoblastoma 2572: 2535: 2249:Dens evaginatus 2203: 2173: 2125:Denture-related 2110:Plasmoacanthoma 2036:Keratoacanthoma 1857: 1855:Lining of mouth 1836: 1832:Torus palatinus 1793: 1776: 1757:Lingual thyroid 1715:Fissured tongue 1705:Crenated tongue 1681: 1664: 1650:Nasolabial cyst 1635:Herpes labialis 1589: 1576: 1571: 1541: 1532: 1509: 1486: 1463: 1452: 1448:Comedocarcinoma 1421: 1419: 1409: 1390: 1377: 1354: 1329: 1303: 1301: 1295: 1266: 1256: 1203: 1166: 1138: 1111:Somatostatinoma 1054:adenocarcinomas 1052: 1030: 1016:Warthin's tumor 1002: 941: 935: 905: 900: 899: 876: 875: 852: 831: 826: 825: 781: 780: 771: 727: 726: 719: 712: 699: 698: 694: 686: 673: 672: 668: 663: 620: 619: 612: 582: 581: 577: 541: 540: 536: 523:(11): 807–812. 514: 513: 506: 476: 475: 471: 441: 440: 436: 405: 404: 400: 356: 355: 351: 315: 314: 310: 296: 295: 291: 286: 269: 257: 246: 228:(also known as 223: 216: 213: 204: 201: 185: 173: 158: 149: 114:alveolar mucosa 103: 70: 34: 31: 23: 22: 15: 12: 11: 5: 3591: 3589: 3581: 3580: 3578:Oral neoplasia 3575: 3570: 3565: 3555: 3554: 3548: 3547: 3544: 3543: 3541: 3540: 3535: 3530: 3525: 3523:Eagle syndrome 3519: 3516: 3515: 3512: 3505: 3504: 3501: 3500: 3498: 3497: 3492: 3487: 3482: 3477: 3472: 3467: 3462: 3457: 3452: 3447: 3445:Cystic hygroma 3442: 3437: 3432: 3427: 3421: 3418: 3417: 3411: 3404: 3403: 3400: 3399: 3397: 3396: 3391: 3390: 3389: 3384: 3379: 3374: 3369: 3359: 3354: 3348: 3345: 3344: 3335: 3328: 3327: 3324: 3323: 3321: 3320: 3315: 3313:Sialolithiasis 3310: 3305: 3300: 3295: 3290: 3289: 3288: 3283: 3273: 3268: 3267: 3266: 3261: 3256: 3251: 3246: 3244:Adenocarcinoma 3241: 3233: 3228: 3223: 3218: 3213: 3211:Myoepithelioma 3208: 3203: 3198: 3193: 3180: 3175: 3170: 3165: 3160: 3155: 3150: 3145: 3140: 3139: 3138: 3128: 3123: 3118: 3113: 3108: 3102: 3099: 3098: 3093: 3086: 3085: 3082: 3081: 3079: 3078: 3077: 3076: 3071: 3061: 3056: 3055: 3054: 3049: 3044: 3039: 3034: 3029: 3024: 3019: 3009: 3004: 2999: 2993: 2990: 2989: 2972: 2965: 2964: 2961: 2960: 2958: 2957: 2952: 2947: 2942: 2941: 2940: 2930: 2925: 2920: 2919: 2918: 2913: 2908: 2898: 2893: 2888: 2887: 2886: 2884:Traumatic bone 2881: 2879:Median palatal 2876: 2871: 2863: 2858: 2853: 2848: 2843: 2838: 2833: 2817: 2812: 2807: 2802: 2797: 2792: 2787: 2782: 2776: 2773: 2772: 2758: 2751: 2750: 2747: 2746: 2744: 2743: 2738: 2733: 2732: 2731: 2726: 2721: 2711: 2706: 2701: 2696: 2691: 2690: 2689: 2679: 2674: 2672:Hypocementosis 2669: 2664: 2659: 2658: 2657: 2652: 2647: 2637: 2632: 2627: 2622: 2621: 2620: 2615: 2605: 2600: 2595: 2594: 2593: 2583: 2577: 2574: 2573: 2548: 2541: 2540: 2537: 2536: 2534: 2533: 2532: 2531: 2526: 2521: 2516: 2506: 2505: 2504: 2494: 2493: 2492: 2487: 2482: 2477: 2467: 2462: 2457: 2452: 2447: 2442: 2437: 2432: 2427: 2422: 2421: 2420: 2410: 2409: 2408: 2406:Neonatal teeth 2398: 2393: 2392: 2391: 2381: 2380: 2379: 2369: 2364: 2359: 2354: 2353: 2352: 2342: 2341: 2340: 2330: 2325: 2320: 2315: 2310: 2305: 2304: 2303: 2293: 2288: 2286:Ectopic enamel 2283: 2278: 2273: 2268: 2263: 2258: 2257: 2256: 2246: 2241: 2236: 2235: 2234: 2224: 2219: 2214: 2208: 2205: 2204: 2186: 2179: 2178: 2175: 2174: 2172: 2171: 2166: 2161: 2156: 2155: 2154: 2144: 2139: 2134: 2133: 2132: 2127: 2122: 2112: 2107: 2102: 2101: 2100: 2090: 2089: 2088: 2081:Oral melanosis 2078: 2073: 2072: 2071: 2066: 2061: 2056: 2051: 2046: 2038: 2033: 2020: 2015: 2010: 2005: 2000: 1995: 1990: 1985: 1980: 1975: 1970: 1965: 1960: 1955: 1950: 1945: 1940: 1935: 1930: 1929: 1928: 1918: 1913: 1908: 1903: 1898: 1893: 1888: 1883: 1881:Bohn's nodules 1878: 1873: 1868: 1866:Amalgam tattoo 1862: 1859: 1858: 1849: 1842: 1841: 1838: 1837: 1835: 1834: 1829: 1824: 1819: 1814: 1809: 1804: 1798: 1795: 1794: 1789: 1782: 1781: 1778: 1777: 1775: 1774: 1769: 1764: 1759: 1754: 1749: 1744: 1743: 1742: 1737: 1732: 1722: 1717: 1712: 1707: 1702: 1697: 1692: 1686: 1683: 1682: 1677: 1670: 1669: 1666: 1665: 1663: 1662: 1657: 1652: 1647: 1642: 1637: 1632: 1627: 1622: 1617: 1616: 1615: 1610: 1605: 1594: 1591: 1590: 1585: 1578: 1577: 1572: 1570: 1569: 1562: 1555: 1547: 1538: 1537: 1534: 1533: 1531: 1530: 1524: 1522: 1515: 1514: 1511: 1510: 1508: 1507: 1502: 1496: 1494: 1488: 1487: 1485: 1484: 1479: 1473: 1471: 1465: 1464: 1462: 1461: 1450: 1445: 1440: 1434: 1432: 1423: 1415: 1414: 1411: 1410: 1408: 1407: 1387: 1385: 1379: 1378: 1376: 1375: 1370: 1369: 1368: 1352: 1351: 1350: 1339: 1337: 1331: 1330: 1328: 1327: 1317: 1315: 1305: 1297: 1296: 1294: 1293: 1288: 1287: 1286: 1281: 1270: 1268: 1267:skin appendage 1262: 1261: 1258: 1257: 1255: 1254: 1249: 1244: 1239: 1234: 1229: 1224: 1223: 1222: 1211: 1209: 1208:Other/multiple 1205: 1204: 1202: 1201: 1196: 1187: 1182: 1176: 1174: 1168: 1167: 1165: 1164: 1159: 1154: 1148: 1146: 1140: 1139: 1137: 1136: 1127: 1125:Klatskin tumor 1122: 1116: 1115: 1114: 1113: 1108: 1103: 1098: 1093: 1082: 1081: 1076: 1067: 1065: 1056: 1042: 1036: 1035: 1032: 1031: 1029: 1028: 1023: 1018: 1012: 1010: 1004: 1003: 1001: 1000: 995: 990: 985: 980: 975: 970: 964: 962: 949: 943: 942: 936: 934: 933: 926: 919: 911: 902: 901: 898: 897: 885: 884: 882: 878: 877: 874: 873: 862: 853: 848: 847: 845: 844:Classification 838: 837: 830: 829:External links 827: 824: 823: 769: 740:(12): rjs020. 717: 710: 692: 684: 666: 610: 575: 554:(1): 110–120. 534: 504: 485:(7): 437–440. 469: 434: 398: 369:(4): 573–578. 349: 328:(2): 204–212. 308: 288: 287: 285: 282: 281: 280: 275: 268: 265: 256: 253: 245: 242: 234:Ackerman tumor 222: 219: 218: 217: 214: 207: 205: 202: 195: 189:histopathology 184: 181: 172: 169: 157: 154: 148: 145: 144: 143: 142: 141: 138: 135: 132: 129: 126: 123: 117: 110: 107: 102: 99: 78: 77: 64: 58: 57: 50: 49: 41: 40: 32: 24: 14: 13: 10: 9: 6: 4: 3: 2: 3590: 3579: 3576: 3574: 3571: 3569: 3566: 3564: 3561: 3560: 3558: 3539: 3536: 3534: 3531: 3529: 3526: 3524: 3521: 3520: 3517: 3510: 3506: 3496: 3493: 3491: 3488: 3486: 3483: 3481: 3478: 3476: 3473: 3471: 3468: 3466: 3463: 3461: 3458: 3456: 3453: 3451: 3448: 3446: 3443: 3441: 3438: 3436: 3433: 3431: 3428: 3426: 3425:Actinomycosis 3423: 3422: 3419: 3415: 3409: 3405: 3395: 3392: 3388: 3385: 3383: 3380: 3378: 3375: 3373: 3370: 3368: 3365: 3364: 3363: 3360: 3358: 3355: 3353: 3350: 3349: 3346: 3342: 3338: 3333: 3329: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3303:Sialodochitis 3301: 3299: 3296: 3294: 3291: 3287: 3284: 3282: 3279: 3278: 3277: 3274: 3272: 3269: 3265: 3262: 3260: 3257: 3255: 3252: 3250: 3247: 3245: 3242: 3240: 3237: 3234: 3232: 3229: 3227: 3224: 3222: 3219: 3217: 3214: 3212: 3209: 3207: 3204: 3202: 3199: 3197: 3194: 3192: 3189: 3186: 3185: 3184: 3181: 3179: 3176: 3174: 3171: 3169: 3166: 3164: 3161: 3159: 3156: 3154: 3151: 3149: 3146: 3144: 3141: 3137: 3134: 3133: 3132: 3129: 3127: 3124: 3122: 3119: 3117: 3114: 3112: 3109: 3107: 3104: 3103: 3100: 3096: 3091: 3087: 3075: 3072: 3070: 3067: 3066: 3065: 3062: 3060: 3057: 3053: 3050: 3048: 3045: 3043: 3040: 3038: 3035: 3033: 3030: 3028: 3025: 3023: 3020: 3018: 3015: 3014: 3013: 3010: 3008: 3005: 3003: 3000: 2998: 2995: 2994: 2991: 2987: 2983: 2982:malocclusions 2979: 2975: 2970: 2966: 2956: 2953: 2951: 2950:Stafne defect 2948: 2946: 2943: 2939: 2936: 2935: 2934: 2931: 2929: 2926: 2924: 2921: 2917: 2914: 2912: 2909: 2907: 2904: 2903: 2902: 2901:Osteonecrosis 2899: 2897: 2896:Osteomyelitis 2894: 2892: 2889: 2885: 2882: 2880: 2877: 2875: 2872: 2870: 2867: 2864: 2862: 2859: 2857: 2854: 2852: 2849: 2847: 2844: 2842: 2839: 2837: 2834: 2832: 2829: 2827: 2823: 2822: 2821: 2818: 2816: 2813: 2811: 2808: 2806: 2803: 2801: 2798: 2796: 2793: 2791: 2788: 2786: 2783: 2781: 2778: 2777: 2774: 2770: 2769:Bones of jaws 2766: 2762: 2756: 2752: 2742: 2739: 2737: 2734: 2730: 2727: 2725: 2722: 2720: 2717: 2716: 2715: 2714:Periodontitis 2712: 2710: 2707: 2705: 2702: 2700: 2697: 2695: 2694:Pericoronitis 2692: 2688: 2685: 2684: 2683: 2680: 2678: 2675: 2673: 2670: 2668: 2665: 2663: 2660: 2656: 2653: 2651: 2650:Granulomatous 2648: 2646: 2643: 2642: 2641: 2638: 2636: 2633: 2631: 2628: 2626: 2623: 2619: 2616: 2614: 2611: 2610: 2609: 2606: 2604: 2603:Eruption cyst 2601: 2599: 2596: 2592: 2589: 2588: 2587: 2584: 2582: 2579: 2578: 2575: 2571: 2567: 2563: 2559: 2555: 2551: 2546: 2542: 2530: 2527: 2525: 2522: 2520: 2517: 2515: 2512: 2511: 2510: 2507: 2503: 2500: 2499: 2498: 2495: 2491: 2488: 2486: 2483: 2481: 2478: 2476: 2473: 2472: 2471: 2468: 2466: 2463: 2461: 2458: 2456: 2453: 2451: 2448: 2446: 2443: 2441: 2438: 2436: 2433: 2431: 2430:Pulp necrosis 2428: 2426: 2423: 2419: 2416: 2415: 2414: 2411: 2407: 2404: 2403: 2402: 2399: 2397: 2394: 2390: 2389:Dens in dente 2387: 2386: 2385: 2382: 2378: 2375: 2374: 2373: 2370: 2368: 2365: 2363: 2360: 2358: 2355: 2351: 2348: 2347: 2346: 2343: 2339: 2336: 2335: 2334: 2331: 2329: 2326: 2324: 2321: 2319: 2316: 2314: 2311: 2309: 2306: 2302: 2299: 2298: 2297: 2294: 2292: 2289: 2287: 2284: 2282: 2281:Discoloration 2279: 2277: 2274: 2272: 2269: 2267: 2264: 2262: 2259: 2255: 2252: 2251: 2250: 2247: 2245: 2242: 2240: 2237: 2233: 2230: 2229: 2228: 2225: 2223: 2220: 2218: 2215: 2213: 2210: 2209: 2206: 2201: 2197: 2193: 2189: 2184: 2180: 2170: 2167: 2165: 2162: 2160: 2157: 2153: 2150: 2149: 2148: 2145: 2143: 2140: 2138: 2135: 2131: 2128: 2126: 2123: 2121: 2118: 2117: 2116: 2113: 2111: 2108: 2106: 2103: 2099: 2096: 2095: 2094: 2091: 2087: 2084: 2083: 2082: 2079: 2077: 2074: 2070: 2067: 2065: 2062: 2060: 2057: 2055: 2052: 2050: 2047: 2045: 2042: 2039: 2037: 2034: 2032: 2029: 2026: 2025: 2024: 2021: 2019: 2016: 2014: 2011: 2009: 2006: 2004: 2001: 1999: 1996: 1994: 1991: 1989: 1988:Lichen planus 1986: 1984: 1981: 1979: 1976: 1974: 1971: 1969: 1966: 1964: 1963:Herpes zoster 1961: 1959: 1956: 1954: 1951: 1949: 1946: 1944: 1941: 1939: 1938:Fordyce spots 1936: 1934: 1931: 1927: 1924: 1923: 1922: 1919: 1917: 1916:Erythroplakia 1914: 1912: 1909: 1907: 1904: 1902: 1899: 1897: 1894: 1892: 1889: 1887: 1884: 1882: 1879: 1877: 1874: 1872: 1869: 1867: 1864: 1863: 1860: 1856: 1852: 1847: 1843: 1833: 1830: 1828: 1825: 1823: 1820: 1818: 1815: 1813: 1810: 1808: 1805: 1803: 1800: 1799: 1796: 1792: 1787: 1783: 1773: 1770: 1768: 1765: 1763: 1760: 1758: 1755: 1753: 1750: 1748: 1745: 1741: 1738: 1736: 1733: 1731: 1728: 1727: 1726: 1723: 1721: 1718: 1716: 1713: 1711: 1708: 1706: 1703: 1701: 1700:Caviar tongue 1698: 1696: 1693: 1691: 1690:Ankyloglossia 1688: 1687: 1684: 1680: 1675: 1671: 1661: 1658: 1656: 1655:Sun poisoning 1653: 1651: 1648: 1646: 1643: 1641: 1638: 1636: 1633: 1631: 1628: 1626: 1623: 1621: 1618: 1614: 1611: 1609: 1606: 1604: 1601: 1600: 1599: 1596: 1595: 1592: 1588: 1583: 1579: 1575: 1568: 1563: 1561: 1556: 1554: 1549: 1548: 1545: 1529: 1526: 1525: 1523: 1520: 1516: 1506: 1503: 1501: 1498: 1497: 1495: 1493: 1489: 1483: 1480: 1478: 1475: 1474: 1472: 1470: 1466: 1459: 1455: 1451: 1449: 1446: 1444: 1441: 1439: 1436: 1435: 1433: 1431: 1427: 1424: 1422:and medullary 1416: 1405: 1401: 1397: 1393: 1389: 1388: 1386: 1384: 1380: 1374: 1371: 1367: 1364: 1363: 1361: 1357: 1353: 1349: 1346: 1345: 1344: 1341: 1340: 1338: 1336: 1332: 1326: 1322: 1319: 1318: 1316: 1313: 1309: 1306: 1298: 1292: 1289: 1285: 1282: 1280: 1277: 1276: 1275: 1272: 1271: 1269: 1263: 1253: 1250: 1248: 1245: 1243: 1240: 1238: 1235: 1233: 1230: 1228: 1225: 1221: 1218: 1217: 1216: 1213: 1212: 1210: 1206: 1200: 1197: 1195: 1191: 1188: 1186: 1183: 1181: 1178: 1177: 1175: 1173: 1169: 1163: 1160: 1158: 1155: 1153: 1150: 1149: 1147: 1145: 1141: 1135: 1131: 1128: 1126: 1123: 1121: 1118: 1117: 1112: 1109: 1107: 1104: 1102: 1099: 1097: 1094: 1092: 1089: 1088: 1087: 1084: 1083: 1080: 1077: 1075: 1072: 1069: 1068: 1066: 1064: 1060: 1057: 1055: 1050: 1046: 1043: 1041: 1037: 1027: 1024: 1022: 1019: 1017: 1014: 1013: 1011: 1009: 1005: 999: 996: 994: 991: 989: 986: 984: 981: 979: 976: 974: 971: 969: 966: 965: 963: 961: 957: 953: 950: 948: 944: 940: 932: 927: 925: 920: 918: 913: 912: 909: 896: 892: 891: 887: 886: 883: 879: 872: 868: 867: 863: 860: 859: 855: 854: 851: 846: 842: 836: 833: 832: 828: 819: 815: 810: 805: 801: 797: 793: 789: 785: 778: 776: 774: 770: 765: 761: 756: 751: 747: 743: 739: 735: 731: 724: 722: 718: 713: 707: 703: 696: 693: 687: 685:0-7216-2921-0 681: 677: 670: 667: 660: 656: 651: 646: 641: 636: 632: 628: 624: 617: 615: 611: 606: 602: 598: 594: 590: 586: 579: 576: 571: 567: 562: 557: 553: 549: 545: 538: 535: 530: 526: 522: 518: 511: 509: 505: 500: 496: 492: 488: 484: 480: 473: 470: 465: 461: 457: 453: 449: 445: 438: 435: 430: 426: 422: 418: 414: 410: 402: 399: 394: 390: 385: 380: 376: 372: 368: 364: 360: 353: 350: 345: 341: 336: 331: 327: 323: 319: 312: 309: 304: 300: 293: 290: 283: 279: 276: 274: 271: 270: 266: 264: 262: 254: 252: 249: 243: 241: 239: 235: 231: 227: 220: 211: 206: 199: 194: 192: 190: 182: 180: 178: 170: 168: 165: 163: 155: 153: 146: 139: 136: 133: 130: 127: 124: 121: 120: 118: 115: 111: 108: 105: 104: 100: 98: 96: 92: 88: 84: 74: 68: 65: 63: 59: 56: 51: 47: 42: 37: 30: 19: 3413: 3340: 3276:Sialadenitis 3235: 3187: 3052:Scissor bite 3047:Retrognathia 3032:Overeruption 3012:Malocclusion 2985: 2865: 2824: 2815:Micrognathia 2768: 2759:Periapical, 2645:Desquamative 2569: 2550:Periodontium 2524:Acid erosion 2465:Taurodontism 2396:Open contact 2308:Enamel pearl 2276:Dilaceration 2239:Concrescence 2068: 2040: 2027: 1854: 1807:Cleft palate 1767:Microglossia 1762:Macroglossia 1747:Glossoptosis 1645:Microcheilia 1640:Macrocheilia 1279:Hidrocystoma 1273: 1199:HĂĽrthle cell 1180:Prolactinoma 1085: 1070: 977: 888: 864: 856: 791: 787: 737: 733: 701: 695: 675: 669: 630: 626: 591:(1): 22–28. 588: 584: 578: 551: 547: 537: 520: 516: 482: 478: 472: 450:(2): 70–74. 447: 443: 437: 415:(1): 63–67. 412: 408: 401: 366: 362: 352: 325: 321: 311: 302: 292: 258: 250: 247: 233: 229: 225: 224: 186: 174: 166: 159: 156:Risk factors 150: 82: 81: 3470:Microstomia 3460:Macrostomia 3450:Gnathophyma 3367:Catathrenia 3362:Sleep apnea 3293:Sialectasis 2836:Dentigerous 2826:Odontogenic 2655:Plasma cell 2591:Gigantiform 2367:Microdontia 2357:Macrodontia 2328:Hyperdontia 2023:Oral cancer 1983:Leukoplakia 1891:Candidiasis 1851:Oral mucosa 1772:Rhabdomyoma 1752:Hypoglossia 1613:Plasma cell 1321:Cystadenoma 1274:sweat gland 1265:Adnexal and 1096:Glucagonoma 633:: 1537379. 191:diagnosis. 3557:Categories 3430:Angioedema 3236:Malignant: 3216:Oncocytoma 3042:Prognathia 2831:periapical 2810:Microgenia 2761:mandibular 2719:Aggressive 2640:Gingivitis 2581:Cementicle 2519:Abfraction 2509:Tooth wear 2502:Edentulism 2497:Tooth loss 2450:Resorption 2435:Pulp polyp 2418:Pulp stone 2362:Meth mouth 2333:Hypodontia 2323:Gemination 2254:Talon cusp 2147:Ulceration 2115:Stomatitis 2093:Pemphigoid 2041:Malignant: 1993:Linea alba 1978:Leukoedema 1958:Herpangina 1926:Giant-cell 1304:and serous 1247:Cylindroma 1232:Oncocytoma 1144:Urogenital 1101:Gastrinoma 1091:Insulinoma 947:Epithelium 284:References 261:metastasis 27:See also: 3568:Carcinoma 3298:Sialocele 3281:Parotitis 3022:Open bite 3017:Crossbite 2795:Cherubism 2765:maxillary 2598:Cementoma 2529:Attrition 2345:Impaction 2313:Fluorosis 2222:Anodontia 2217:Ankylosis 2105:Pemphigus 1725:Glossitis 1620:Cleft lip 1598:Cheilitis 1302:mucinous, 1284:Syringoma 1220:Carcinoid 1172:Endocrine 960:carcinoma 956:Papilloma 890:eMedicine 861:: M8051/3 255:Prognosis 244:Treatment 183:Diagnosis 171:Locations 62:Specialty 3308:Sialosis 3259:Lymphoma 3131:Mucocele 3027:Overbite 2780:Agnathia 2741:Teething 2566:alveolus 2562:cementum 2514:Abrasion 2490:Occlusal 2475:Avulsion 2440:Pulpitis 2384:Odontoma 2130:Herpetic 2120:Aphthous 1630:Eclabium 1420:lobular, 1335:Mucinous 1086:pancreas 1049:Adenomas 895:derm/452 818:28274074 764:24968418 659:30918740 570:11443616 529:14765750 267:See also 221:Subtypes 67:Oncology 3394:Snoring 3352:Bruxism 3188:Benign: 3037:Overjet 2997:Bruxism 2891:Osteoma 2729:Chronic 2554:gingiva 2028:Benign: 1921:Fibroma 1608:Angular 1603:Actinic 1418:Ductal, 1314:general 1300:Cystic, 1242:Apudoma 1021:Thymoma 871:D018289 809:5324519 755:3855215 650:6408996 605:6757186 499:6732584 464:8164156 429:8180579 393:2021541 384:1972357 344:9669801 93:or use 91:tobacco 3136:Ranula 2608:Epulis 2470:Trauma 2318:Fusion 2227:Caries 2200:enamel 2196:dentin 1791:Palate 1679:Tongue 1519:Acinar 1383:Serous 1312:Cystic 1106:VIPoma 1071:tract: 1040:Glands 939:cancer 816:  806:  762:  752:  708:  682:  657:  647:  603:  568:  548:Cancer 527:  497:  462:  427:  391:  381:  342:  322:Cancer 238:atypia 232:, and 69:  3513:Other 2188:Teeth 858:ICD-O 147:Cause 95:snuff 55:penis 3475:Noma 2980:and 2763:and 2568:) – 2192:pulp 1587:Lips 1521:cell 866:MeSH 814:PMID 760:PMID 738:2012 706:ISBN 680:ISBN 655:PMID 631:2019 601:PMID 566:PMID 525:PMID 495:PMID 460:PMID 425:PMID 389:PMID 340:PMID 804:PMC 796:doi 750:PMC 742:doi 645:PMC 635:doi 593:doi 556:doi 487:doi 483:110 452:doi 417:doi 413:29B 379:PMC 371:doi 330:doi 3559:: 3339:– 2984:– 2976:, 2564:, 2560:, 2556:, 2198:, 2194:, 1853:– 1456:/ 1402:/ 1398:/ 1394:/ 1358:/ 893:: 869:: 812:. 802:. 792:11 790:. 786:. 772:^ 758:. 748:. 736:. 732:. 720:^ 653:. 643:. 629:. 625:. 613:^ 599:. 587:. 564:. 552:92 550:. 546:. 521:26 519:. 507:^ 493:. 481:. 458:. 448:23 446:. 423:. 411:. 387:. 377:. 367:63 365:. 361:. 338:. 326:83 324:. 320:. 2828:: 2552:( 2202:) 2190:( 1566:e 1559:t 1552:v 1323:/ 1192:/ 1132:/ 1051:/ 958:/ 930:e 923:t 916:v 850:D 820:. 798:: 766:. 744:: 714:. 690:. 688:. 661:. 637:: 607:. 595:: 589:5 572:. 558:: 531:. 501:. 489:: 466:. 454:: 431:. 419:: 395:. 373:: 346:. 332:: 20:)

Index

Carcinoma cuniculatum
List of verrucous carcinoma subtypes

penis
Specialty
Oncology
Edit this on Wikidata
squamous cell carcinoma
tobacco
snuff
alveolar mucosa
alcohol consumption
sole of the foot
histopathology
Low-magnification micrograph of penile verrucous carcinoma. The tumor is characterized by prominent papillomatosis.
High magnification. There is prominent acanthosis. The tumor front is broad-based and pushes the subepithelial tissues.
atypia
metastasis
List of cutaneous conditions
List of verrucous carcinoma subtypes
"Head and Neck Tumors"
"Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use"
doi
10.1002/(sici)1097-0142(19980715)83:2<204::aid-cncr2>3.0.co;2-q
PMID
9669801
"High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India"
doi
10.1038/bjc.1991.133
PMC

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